ライフサイエンスコーパス: CLA

1 CLA and CNA significantly reduced body weight and fat ma

2 CLA and CNA significantly reduced serum leptin and tumou

3 CLA and OCS act non-additively to activate atNHE1, indic

4 CLA attenuated the increase in BMI (0.5 +/- 0.8) compare

5 CLA exerts its anti-carcinogenic effect by reducing VEGF

6 CLA expressed on CD43 was found exclusively on the high-

7 CLA has a wide range of biological effects, including bo

8 CLA significantly increased bone markers without major c

9 CLA supplementation for 7 +/- 0.5 mo decreased body fatn

10 CLA supplementation significantly prevented ovariectomy-

11 CLA treatment increased serum parathyroid hormone (PTH)

12 CLA was microencapsulated by spray drying in ten varied

13 CLA(+) is expressed on the surface of circulating CD45RO

14 CLA(+) TH2 T cells were markedly expanded in both childr

15 CLA+ and alpha4beta7+ memory T cells were isolated and c

16 CLA+ CD43 purified from human T cells supported tetherin

17 CLA-rich eggs and soy control eggs were produced by addi

18 CLA-yolk mayonnaise was more viscous, had greater storag

19 CLA/ESL mediates adhesion of T cells to inflamed vascula

20 CLA:M:PPC (1:1:3) microparticles demonstrated better mor

21 CLA:M:PPC (1:1:3) showed the most promising results, thu

22 had increased CLA(+) /CLA(-) Th2 (P < .007), CLA(+) Tc2 (P = .04), and CLA(+) Th22 (P < .05) frequenc

23 CD36 and LIMPII analog 1, CLA-1, and its splicing variant, CLA-2 (SR-BI and SR-BII

24 e members of the SR-B family, namely, CLA-1, CLA-2, and CD36, mediate recognition of bacteria not onl

25 t bacterial uptake that is enhanced by CLA-1/CLA-2 overexpression.

26 cytosolic accumulation of bacteria in CLA-1/CLA-2-overexpressing HeLa cells.

27 soy control eggs were produced by adding 10% CLA-rich soy oil or 10% of control unmodified soy oil to

28 from mountain areas showed average c-9, t-11 CLA content higher than those from prairie districts.

29 ilk yogurts showed lower values of c-9, t-11 CLA content on lipid basis compared to full-fat yogurts.

30 roducts naturally enriched in cis-9,trans-11 CLA (and trans-11 18:1) on the blood lipid profile, the

31 dairy products enriched with cis-9,trans-11 CLA and trans-11 18:1 did not significantly affect body

32 ducts naturally enriched with cis-9,trans-11 CLA and trans-11 18:1 do not appear to have a significan

33 erse association between the cis-9, trans-11 CLA in adipose tissue and diabetes risk is consistent wi

34 The cis-9, trans-11 CLA isomer was associated with a lower risk of diabetes.

35 determine the association between the 9c,11t-CLA isomer in adipose tissue and risk of MI.

36 Adipose tissue 9c,11t-CLA was associated with a lower risk of MI in basic and

37 9c,11t-CLA, which is present in meaningful amounts in the milk

38 The trans-10, cis-12 CLA isomer was not detected in adipose tissue.

39 The cis-9, trans-11 and trans-10, cis-12 CLA isomers in adipose tissue and 48 other fatty acids w

40 nflammatory proteins were increased by 10,12-CLA compared with bovine serum albumin vehicle in the ad

41 ns-10,cis-12-conjugated linoleic acid (10,12-CLA) activate the inflammatory signaling that promotes i

42 10,12-CLA-induced IL-8, IL-6, IL-1beta, and COX-2 mRNA levels

43 ized that they played the same role in 10,12-CLA-mediated inflammation.

44 Consistent with these data, 10,12-CLA-mediated secretions of IL-8 and IL-6 from AD50 cultu

45 d the inflammatory capacity of CM from 10,12-CLA-treated cultures.

46 We conclude that the CHO-131(+)CLA(+) T cell subset is enriched in P-selectin binding c

47 mory cell markers, CHO-131(+) and CHO-131(-) CLA(+) T cells have an overlapping skin-tropic and memor

48 inding capacity of CHO-131(+) and CHO-131(-) CLA(+) T cells revealed a significantly greater P-select

49 te supplementation in rodents elevates NO(2)-CLA levels in plasma, urine, and tissues, which in turn

50 erexpression abrogated cell surface HECA-452/CLA expression, reduced the number of rolling leukocytes

51 specially formulated diet consisting of 0.5% CLA for 24 days.

52 re randomly assigned to receive 3 g/d of 80% CLA (50:50 cis-9,trans-11 and trans-10,cis-12 isomers) o

53 with the phosphatase inhibitor calyculin-A (CLA) increase Na(+) transport capacity without affecting

54 Conjugated linoleic acid (CLA) and conjugated nonadecadienoic acid (CNA) have been

55 imental studies on conjugated linoleic acid (CLA) and insulin regulation suggested that CLA could be

56 of 2 dietary oils, conjugated linoleic acid (CLA) and safflower oil (SAF), on body weight and composi

57 ch in trans, trans conjugated linoleic acid (CLA) are significantly more viscous, have more phospholi

58 urally enriched in conjugated linoleic acid (CLA) exists.

59 Conjugated linoleic acid (CLA) has been shown to be an effective supplement for re

60 n for the elderly; conjugated linoleic acid (CLA) has been shown to improve overall bone mass when ca

61 Conjugated linoleic acid (CLA) has the unique property of inducing regression of p

62 tes the effects of conjugated linoleic acid (CLA) in preventing bone loss, using an ovariectomised mo

63 Many studies with conjugated linoleic acid (CLA) indicate that it has a protective effect against ma

64 Conjugated linoleic acid (CLA) is a family of positional and geometric isomers wit

65 Conjugated linoleic acid (CLA) is a supplemental dietary fatty acid that decreases

66 Conjugated Linoleic Acid (CLA) is fatty acid found endogenously in food sources th

67 Herein, conjugated linoleic acid (CLA) is identified as the primary endogenous substrate f

68 GC-FID), including conjugated linoleic acid (CLA) isomeric profile (Ag(+)-HPLC), and nutritional valu

69 identification of conjugated linoleic acid (CLA) isomers has been developed in which silver ion liqu

70 e development of a conjugated linoleic acid (CLA) oil-in-water beverage emulsion containing acacia gu

71 n the synthesis of conjugated linoleic acid (CLA) partial glycerides, which presented nutraceutical p

72 sity is to consume conjugated linoleic acid (CLA) supplements containing isomers cis-9, trans-11 and

73 aturated FA (UFA), conjugated linoleic acid (CLA), n-3 FA, and C18:1cis9 to C16 ratio.

74 ty acids including conjugated linoleic acid (CLA), polyunsaturated fatty acids C18:2(n-6) and C18:3(n

75 ration products of conjugated linoleic acid (CLA).

76 the main source of conjugated linoleic acid (CLA; 18:2n-7t), which is produced by the ruminal biohydr

77 id, docosapentaenoic acid, arachidonic acid, CLA:9c11t and gamma linolenic acid.

78 g more n-3 FA and conjugated linoleic acids (CLA) than conventionally produced dairy products.

79 either a study of skin lesions or activated CLA(+) T-cell subsets in peripheral blood.

80 ho were receiving either 4 g/d of 78% active CLA isomers (3.2 g/d: 39.2% cis-9,trans-11 and 38.5% tra

81 Chaperone-like activity (CLA) was evaluated by measuring the ability of alpha-cry

82 nd high levels of the skin-homing addressins CLA, CCR4, and CCR6.

83 ed to as cutaneous lymphocyte-associated Ag (CLA) T cells) correlates with E-selectin binding, yet wh

84 % of Treg expressed cutaneous lymphocyte Ag (CLA) and 73% expressed CCR6.

85 e not only the CLnA concentrations, but also CLA in egg-yolk lipids.

86 .001]), with less significant effects among CLA(+) T cells (IL-22: 11 vs 7.5, P = .04).

87 uencies, which were highly significant among CLA(-) cells (IL-22: 3.7 vs 1.7 [P < .001] and IL-17: 1.

88 group than in the PCV group (P = .014); and CLA was expressed more frequently in the pneumonia group

89 -) Th2 (P < .007), CLA(+) Tc2 (P = .04), and CLA(+) Th22 (P < .05) frequencies than controls.

90 7pA) competed with E. coli K12 for CLA-1 and CLA-2 binding.

91 l adhesion and cytosolic invasion, CLA-1 and CLA-2 may play an important role in infection and sepsis

92 and replicate intracellularly in CLA-1- and CLA-2-overexpressing HeLa, but both L-37pA and D-37pA pr

93 In this study, CLA-1- and CLA-2-stably transfected HeLa and HEK293 cells demonstra

94 gut (alpha4beta7, CCR6) and skin (CCR10 and CLA).

95 d the skin-homing receptors CCR4, CCR10, and CLA and migrated in response to CCL17/CCL27.

96 n of other skin addressins (CCR6, CCR10, and CLA).

97 tin and CD27 but strongly expressed CCR4 and CLA, a phenotype suggestive of skin resident effector me

98 d CD8(+) T cells were compared in CLA(-) and CLA(+) populations.

99 aneous lymphocyte antigen (CLA)-positive and CLA(-) T-cell subsets in patients with AD and control su

100 Cutaneous lymphocyte-associated antigen (CLA(+) ) T cells are specialized for skin homing and rep

101 hat cutaneous lymphocyte-associated antigen (CLA), a functional E-selectin ligand (ESL), is selective

102 med cutaneous lymphocyte-associated antigen (CLA), a skin-homing receptor, than do circulating HSV-sp

103 ope cutaneous lymphocyte-associated antigen (CLA).

104 CD)4+, CD45RO+, cutaneous leukocyte antigen (CLA)+ T cells that homes to the skin.

105 oming markers, cutaneous lymphocyte antigen (CLA) and alpha4beta7 integrin, are used to determine whe

106 high levels of cutaneous lymphocyte antigen (CLA) and chemokine receptor (CCR)4.

107 expression of cutaneous lymphocyte antigen (CLA) in ILCs.

108 -selectin, and cutaneous lymphocyte antigen (CLA) on S. pneumoniae-specific plasmablasts was examined

109 s positive for cutaneous lymphocyte antigen (CLA) were increased fourfold in all CD4+ and CD8+ T cell

110 T-cell, cutaneous lymphocyte antigen (CLA)(+) and CCR4(+) T-cell and cytokine responses were s

111 rities between cutaneous lymphocyte antigen (CLA)(+) polarized T-cell subsets in children versus adul

112 contained few cutaneous lymphocyte antigen (CLA)(+) T cells, the cell type thought to provide cutane

113 CXCR3, but not cutaneous lymphocyte antigen (CLA), on circulating T cell subsets was associated with

114 ubsets in both cutaneous lymphocyte antigen (CLA)-positive and CLA(-) T-cell subsets in patients with

115 mir1-mediated resistance to corn leaf aphid (CLA; Rhopalosiphum maidis), a phloem sap-sucking insect

116 These molecules were functional, as CLA+ Treg showed CD62E ligand activity and demonstrable

117 ng small interfering NFkappaB p65 attenuated CLA suppression of glucose transporter 4 and peroxisome

118 We further demonstrated that blood CLA+ Treg inhibited CD4+CD25- T cell proliferation induc

119 ain emphasized the divergent effects of both CLA isomers on different pathways, but also revealed a l

120 yvitamin D3 concentration was not changed by CLA.

121 pendent bacterial uptake that is enhanced by CLA-1/CLA-2 overexpression.

122 Furthermore, foliar feeding by CLA rapidly sends defensive signal(s) to the roots that

123 Feeding by CLA triggers the rapid accumulation of mir1 transcripts

124 We report circulating skin-homing CD22+CLA+B cells in healthy volunteers and melanoma patients

125 Circulating CLA(+) T cells may be a reliable surrogate marker of the

126 PTDM (N = 24), the frequency of circulating CLA(+) (skin-homing) Tregs was decreased (1.53% vs 3.99%

127 e latest advancements reached on circulating CLA(+) in AD and the great potential they harbor in unde

128 Isomerization of cis,trans and trans,cis CLA to trans,trans isomers was observed mainly for the m

129 e significantly higher in the trans10, cis12-CLA group, whereas plasma triglyceride, NEFA, glucose, a

130 rast, the treatment effect of trans10, cis12-CLA was mainly explained by up-regulation of key enzymes

131 of CLA, cis9, trans11-CLA and trans10, cis12-CLA, affected lipid and glucose metabolism, as well as h

132 AA patients had increased CLA(+) /CLA(-) Th2 (P < .007), CLA(+) Tc2 (P = .04), and CLA(+)

133 the analysis of CLA isomers in a commercial CLA supplement, milk fat, and the lipid extract from a L

134 single-isomer studies, and results comparing CLA isomers were inconclusive.

135 due to inflammatory signaling and considers CLA's linkage with lipogenesis, lipolysis, thermogenesis

136 The mobile phase containing CLA isomers eluting from the Ag(+)-LC column flows throu

137 djustment to the median dose of 3.2 g CLA/d, CLA was effective and produced a reduction in fat mass f

138 001) CONCLUSION: Given at a dose of 3.2 g/d, CLA produces a modest loss in body fat in humans.

139 The aim of our study was to determine CLA's effects on energy expenditure, macronutrient utili

140 The aim of this study was to determine CLA's efficacy with regard to change in fat and body mas

141 Dietary CLA and nitrite supplementation in rodents elevates NO(2

142 intravital microscopy, we show that, during CLA-induced regression of pre-established atherosclerosi

143 on of 113 liver cytosolic proteins by either CLA isomer.

144 was moderate, and the proportion expressing CLA was low.

145 nzymatic and cellular mechanisms account for CLA nitration, including reactions catalyzed by mitochon

146 pA and D-37pA) competed with E. coli K12 for CLA-1 and CLA-2 binding.

147 esented describe a novel functional role for CLA in the regulation of monocyte adhesion, polarization

148 itioned medium (CM) model, CM collected from CLA-treated AD50 but not AD0 cultures induced IL-8 and I

149 After adjustment to the median dose of 3.2 g CLA/d, CLA was effective and produced a reduction in fat

150 y 0.128-1.501, 0.405-1.250 and 0.433-0.976 g CLA/100 g fat.

151 loss compared with placebo was -0.024 kg x g CLA(-1) x wk(-1) (P=0.03).

152 P-selectin glycoprotein ligand-1 glycoform "CLA," and CD43.

153 n was reduced during sleep in the CLA group (CLA: -3.3 +/- 2.6%; placebo: 0.3 +/- 5.7%).

154 ine secretion in the order of CD36 > CLA-2 > CLA-1 in HEK293 cells.

155 of cytokine secretion in the order of CD36 > CLA-2 > CLA-1 in HEK293 cells.

156 After only 3h, OM-RML gave the highest CLA conversion (54% at 40 degrees C with 1:3M ratio of g

157 nt groups and Th2 skewing in the skin-homing CLA+ cells of peanut allergic patients.

158 roliferation predominates in the skin-homing CLA+ subset, whilst peanut-tolerant groups have a mixed

159 aimed to compare frequencies of skin homing (CLA(+) ) vs systemic (CLA(-) ) "polar" CD4(+) and CD8(+)

160 tion markers and frequencies of skin-homing (CLA(+)) versus systemic (CLA(-)) "polar" CD4 and CD8 T-c

161 vealed cytosolic accumulation of bacteria in CLA-1/CLA-2-overexpressing HeLa cells.

162 g CD4(+) and CD8(+) T cells were compared in CLA(-) and CLA(+) populations.

163 those in control subjects, but decreases in CLA(+) TH1 T-cell numbers were greater in children with

164 ke in adults, no imbalances were detected in CLA(-) T cells from pediatric patients with AD nor were

165 ol subjects, with significant differences in CLA(+) T-cell numbers (P < .01).

166 with AD, with no significant differences in CLA(-) T-cell numbers.

167 to survive and replicate intracellularly in CLA-1- and CLA-2-overexpressing HeLa, but both L-37pA an

168 ming growth factor beta are each involved in CLA expression by memory HSV type 2 (HSV-2)-specific CD4

169 sn-1 mono and sn-1,3 diacylglycerols rich in CLA, with a ratio of sn-1,3/sn-1,2 regioisomers of 21.8,

170 AA patients had increased CLA(+) /CLA(-) Th2 (P < .007), CLA(+) Tc2 (P = .04), and

171 ly, use of bifidobacteria slightly increased CLA relative content in the conventional fermented milks

172 g bacterial adhesion and cytosolic invasion, CLA-1 and CLA-2 may play an important role in infection

173 Mixed isomer CLA supplementation, but not placebo, positively altered

174 oxidative stability of conjugated linoleic (CLA) and linoleic (LA) acids in different chemical forms

175 g cis-9 trans-11, C18:2 conjugated linoleic (CLA-1.4 times), and alpha-linolenic acids (ALA-1.6 times

176 We recruited 23 subjects from our main CLA efficacy study who were receiving either 4 g/d of 78

177 od T cells expressing tissue homing markers (CLA, beta7, CD49d).

178 Meanwhile, CLA significantly reduced femur tartrate resistant acid

179 the sympathetic nervous system in mediating CLA's antiobesity properties.

180 , whilst peanut-tolerant groups have a mixed CLA/alpha4beta7 response (P = 0.008).

181 In model 1, a differentiation model, CLA activation of MAPK and induction of interleukin-8 (I

182 Pasture-grazing dairy cows have more CLA in their milk than do grain-fed cows.

183 at three members of the SR-B family, namely, CLA-1, CLA-2, and CD36, mediate recognition of bacteria

184 Nitro-conjugated linoleic acid (NO2-CLA) is preferentially formed, constitutes the most abun

185 y, human serum albumin was found to bind NO2-CLA both non-covalently and to form covalent adducts at

186 presence of two electrophilic centers in NO2-CLA located on the beta- and delta-carbons with respect

187 new insights into the chemical basis of NO2-CLA signaling actions.

188 this work, we examined the reactions of NO2-CLA with low molecular weight thiols (glutathione, cyste

189 pwise mechanisms with thiolate attack on NO2-CLA as rate-controlling step.

190 Moreover, we estimate that 98% of CLA(+) effector memory T cells are resident in normal sk

191 Although the ability of CLA to inhibit angiogenesis in the peripheral nervous sy

192 n (+/-SD) percentage of total fatty acids of CLA for the cis-9, trans-11 isomer in adipose tissue was

193 the study was to test whether the amount of CLA in adipose tissue is associated with risk of diabete

194 /O3-MS method was applied to the analysis of CLA isomers in a commercial CLA supplement, milk fat, an

195 However, causality of CLA-mediated responses to body fat loss, particularly th

196 tives were (1) compare the FA composition of CLA-rich yolk granules and plasma, relative to standard

197 The contents of CLA and n-3 FA in a serving of whole milk (3.25% fat) in

198 Nitroalkene derivatives of CLA and their metabolites are detected in the plasma of

199 sed for the direct and fast determination of CLA isomers at low concentrations and in complex lipid m

200 The effect of CLA in lowering BMI was detected during the last 8 wk of

201 to demonstrate the anti-angiogenic effect of CLA in the brain, and suggests that CLA be explored as a

202 This comparison indicated that the effect of CLA was linear for up to 6 mo and then slowly approached

203 However, potential effects of CLA and calcium on bone mass during a period of bone los

204 l models have reported beneficial effects of CLA on atherosclerosis.

205 investigation of the safety and efficacy of CLA supplementation in children is recommended.

206 ing in the skin, and thus, the evaluation of CLA(+) T cells in the blood may eliminate the need for s

207 Except of CLA(-) Tc1 cells (P = .03), IFN-gamma levels were mostly

208 The expansion of CLA-expressing effector memory CD8+ T cells in response

209 s develop strong and selective expression of CLA and E-selectin ligand while responding to HSV antige

210 s was observed mainly for the methyl form of CLA.

211 A significantly lower frequency of CLA(+) IFN-gamma-producing cells was observed in patient

212 In this way, de novo identification of CLA positional isomers, i.e. without requiring compariso

213 ic cells are particularly potent inducers of CLA on HSV-reactive CD4 T cells.

214 We explored how two isomers of CLA, cis9, trans11-CLA and trans10, cis12-CLA, affected

215 in resident T cells expressed high levels of CLA, CCR4, and CCR6, and a subset expressed CCR8 and CXC

216 Proposed antiobesity mechanisms of CLA include regulation of (a) adipogenesis, (b) lipid me

217 ation were measured before and after 6 mo of CLA supplementation by using whole-room indirect calorim

218 labeled dietary fat oxidation after 6 mo of CLA supplementation given with a breakfast meal.

219 had higher Bet v 1-specific proliferation of CLA(+) and CCR4(+) T cells compared with patients with b

220 ility (CLA isomer profile, quantification of CLA and volatile compounds by SPME coupled with CG-MS) d

221 E-selectin on tumor vessels, recruitment of CLA(+) CD8(+) T cells, and histological evidence of tumo

222 ts are the most important dietary sources of CLA, we have investigated the CLA concentrations and add

223 entifying these cells as possible sources of CLA-promoting cytokines.

224 did not influence the oxidative stability of CLA, however its presence improved physical-chemical cha

225 gs and (3) compare the emulsion stability of CLA-yolk mayonnaise.

226 Interestingly, CHO-131 stains a subset of CLA(+) T cells.

227 d, double-blind, placebo-controlled trial of CLA in 62 prepubertal children aged 6-10 y who were over

228 CELL." E-Ig reactivity was most prominent on CLA in mouse cells and on HCELL in human cells.

229 uencies of TH22 T cells within the CLA(+) or CLA(-) compartments.

230 l women with type 2 diabetes received SAF or CLA (8 g oil/d) during two 16-wk diet periods separated

231 < .0001), and frequencies of IL-13-producing CLA(+) cells were also correlated with IgE levels and SC

232 Based on homing receptor profile, CLA+ Treg should enter normal skin.

233 ocytes and dendritic cells from PBMC reduces CLA expression by HSV-2-responsive CD4 lymphoblasts, whi

234 gC tagged alphaB-crystallin displayed robust CLA.

235 e change in energy expenditure during sleep (CLA: 0 +/- 38 kcal; placebo: -43 +/- 90 kcal).

236 here were no differences in Bet v 1-specific CLA(+) and CCR4(+) proliferation and cytokine secretion

237 state of PA correlates with peanut-specific CLA responses, with tolerance associated with predominan

238 cal characteristics and oxidative stability (CLA isomer profile, quantification of CLA and volatile c

239 aled that it is possible to produce a stable CLA oil-in-water emulsion for using in beverages.

240 cts of the addition of CPP on the structure, CLA, and cell transduction properties of alphaB-crystall

241 In this study, CLA-1- and CLA-2-stably transfected HeLa and HEK293 cell

242 ies of skin-homing (CLA(+)) versus systemic (CLA(-)) "polar" CD4 and CD8 T-cell subsets in patients w

243 encies of skin homing (CLA(+) ) vs systemic (CLA(-) ) "polar" CD4(+) and CD8(+) and activated T-cell

244 c9,t11-CLA lowered triacylglycerol (P </= 0.01) and had no effe

245 and cell studies suggest that VA and c9,t11-CLA may be hypocholesterolemic and antiatherogenic, epid

246 -9,trans-11 conjugated linoleic acid (c9,t11-CLA), are less clear.

247 We determined the effects of VA, c9,t11-CLA, and iTFA, in the context of highly controlled diets

248 , with the requirement of VA, but not c9,t11-CLA, to be listed under TFA on the Nutrition Facts Panel

249 y 3% VA, approximately 3% iTFA, or 1% c9,t11-CLA.

250 g two months of storage at room temperature, CLA:PPC (1:4) was selected for comparisons.

251 In this study, we demonstrate that CLA inhibits CXCR4 expression, resulting in a failure of

252 tic-adhesion assay, we provide evidence that CLA prevents monocytes from binding to ICAM-1 and subseq

253 risk is consistent with the hypothesis that CLA may be involved in insulin regulation.

254 Our results indicate that CLA administration significantly reduces angiogenesis in

255 We show that CLA inhibits human peripheral blood monocyte cell adhesi

256 These data suggest that CLA instigates the release of inflammatory signals from

257 The data suggest that CLA, along with dietary calcium, has great potential to

258 (CLA) and insulin regulation suggested that CLA could be associated with risk of diabetes, but epide

259 ffect of CLA in the brain, and suggests that CLA be explored as a therapeutic treatment for cancer an

260 The CLA(+) TH1/TH2 and TC1/TC2 ratio was highly imbalanced i

261 The CLA, vaccenic acid, C18:39c12c15c, total C18:1 trans and

262 in the change in fat utilization between the CLA (4 +/- 8 g) and placebo (-7 +/- 11 g) groups during

263 However, feeding regimens that enhance the CLA content of milk also increase concentrations of tran

264 and produced a reduction in fat mass for the CLA group alone (0.05 +/- 0.05 kg/wk; P<0.001) and for t

265 e (0.05 +/- 0.05 kg/wk; P<0.001) and for the CLA group compared with placebo (0.09 +/- 0.08 kg/wk; P<

266 al body weight was smaller (P = 0.02) in the CLA group (-0.09 +/- 0.9%) than in the placebo group (0.

267 bsorptiometry was smaller (P = 0.001) in the CLA group (-0.5 +/- 2.1%) than in the placebo group (1.3

268 creased significantly more (P = 0.05) in the CLA group (-5.1 +/- 7.3 mg/dL) than in the placebo group

269 ineral accretion was lower (P = 0.04) in the CLA group (0.05 +/- 0.03 kg) than in the placebo group (

270 from protein was reduced during sleep in the CLA group (CLA: -3.3 +/- 2.6%; placebo: 0.3 +/- 5.7%).

271 subjects completed the trial (n = 28 in the CLA group, n = 25 in the placebo group).

272 ary sources of CLA, we have investigated the CLA concentrations and additionally the fatty acid profi

273 skin-resident T cells, while maintaining the CLA(+)CCR4(+) skin-homing phenotype as well as a diverse

274 The physical-chemical properties of the CLA microparticles were characterised by core retention,

275 The predominance of the CLA+ response to peanut in peanut allergic patients is c

276 y on T cells, can also be decorated with the CLA epitope and serve as an E-selectin ligand.

277 tered frequencies of TH22 T cells within the CLA(+) or CLA(-) compartments.

278 somers, i.e. without requiring comparison to CLA standards, was achieved.

279 40 degrees C with 1:3M ratio of glycerol to CLA).

280 eters aphid settling)-mediated resistance to CLA compared with B73 and Tx601 maize susceptible inbred

281 JA, contributed to heightened resistance to CLA in maize.

282 ir1-Cys Protease provides direct toxicity to CLA.

283 evated ratios of alpha(4)beta(7)(+) Tregs to CLA(+) Tregs (odds ratio, 18.1; P = .020).

284 The content of total CLA and the percentage of its t11,c13 isomer were higher

285 plored how two isomers of CLA, cis9, trans11-CLA and trans10, cis12-CLA, affected lipid and glucose m

286 ere significantly lower in the cis9, trans11-CLA group, compared with control mice consuming linoleic

287 al properties or emulsion stability by using CLA-rich eggs.

288 I analog 1, CLA-1, and its splicing variant, CLA-2 (SR-BI and SR-BII in rodents), are human high dens

289 ace method was used and 10% w/w AG, 3.5% w/w CLA and 0.3% w/w XG was introduced as the optimum formul

290 l properties are needed to establish whether CLA(+) memory subsets can be used as biomarkers and a su

291 This review examines whether CLA's antiobesity properties are due to inflammatory sig

292 ll characterized, it remains unknown whether CLA also affects vascular morphology in the central nerv

293 is a meta-analysis of human studies in which CLA was provided as a dietary supplement to test its eff

294 esulting search to identify studies in which CLA was provided to humans in randomized, double-blinded

295 e identified a novel mechanism through which CLA alters monocyte function.

296 Understanding the mechanisms through which CLA mediates its atheroprotective effect may help to ide

297 gical properties of mayonnaise prepared with CLA-rich eggs to control eggs and (3) compare the emulsi

298 Supplementation with CLA and SAF exerted different effects on BMI, total and

299 Supplementation with CLA reduced body mass index (BMI) (P = 0.0022) and total

300 aegypti mosquitoes infected with the wMelPop-CLA strain of Wolbachia and in Drosophila melanogaster a