ライフサイエンスコーパス: MDC

1 MDC are a large family of membrane-bound proteins contai

2 MDC blockade was deleterious in the survival of mice aft

3 MDC frequencies tended to be reduced in HIV infection (1

4 MDC mRNA and protein expression were markedly induced in

5 MDC-associated IL-12 production was markedly reduced in

6 MDC-enriched cells were either CD123(+) or CD123(-), but

7 MDC-expressing DCs specifically attracted T lymphocytes

8 MDC-L (ADAM 28), a member of the ADAM (a disintegrin and

9 MDC-staining and the GFP-AtATG8e fusion protein can now

10 MDCs activated with lactobacilli clearly skewed CD4(+) a

11 MDCs and PDCs exposed to either rAd5 or rAd35 encoding f

12 MDCs derived in vitro suppressed angiogenesis in vivo th

13 MDCs were more susceptible to both rAd35 and rAd5 than w

14 < .001), IL-10 (P = .01), IP-10 (P = .0001), MDC (P < .001), MIP-1alpha, (P < .001), MIP-1beta (P = .

15 of CC (I-309, Exodus-1, TARC, RANTES, MCP-1, MDC, and MIP-1 alpha and -1 beta), CXC (GRO-alpha, -beta

16 quence in the disintegrin domain of ADAM-15 (MDC-15; metargidin) highlighted ADAM-15 as a protein par

17 ADAM 28 (MDC-L) is expressed by human lymphocytes and contains a

18 participants (21/112) did not meet accepted MDC for Moebius syndrome because they had abduction defi

19 st a potential role for the lymphocyte ADAM, MDC-L, in the interaction of lymphocytes with alpha(4)be

20 Consistent with this finding, virtually all MDCs isolated from the tissues or draining lymph nodes o

21 30 cross-sectional subjects revealed that an MDC:PDC ratio more than or equal to 1.78 was associated

22 In summary, SDF-1 and MDC are platelet agonists that activate distinct intrace

23 Treatment of platelets with SDF-1 and MDC rapidly exposed P-selectin (CD62P) on the cell surfa

24 When SDF-1 and MDC were added together, full and brisk platelet aggrega

25 Of the chemokines tested, SDF-1 and MDC were the only 2 that activated platelets.

26 In contrast, TARC, MCP-1, and MDC were not induced, suggesting the existence of distin

27 Whereas ADAM8, ADAM15, and MDC-L (ADAM28) are expressed in specific cell types and

28 We found that ADAM8, ADAM15, and MDC-L, but not ADAM17, catalyzed ectodomain shedding of

29 es remotely the expression of TARC/CCL17 and MDC/CCL22 in the lungs.

30 ttern of CCR4 and its ligands TARC/CCL17 and MDC/CCL22 in the peripheral blood and skin of patients w

31 ssion of the two CCR4 ligands TARC/CCL17 and MDC/CCL22.

32 egulated chemokine; also known as CCL17) and MDC (macrophage-derived chemokine; CCL22).

33 ndicate that lymph node Langerhans cells and MDC are APC needed for induction of the protective respo

34 pes (interleukin-8, interleukin-12, GRO, and MDC).

35 determined in vitro, but only methylone and MDC (1, 3 mg/kg, iv) produced significant elevations in

36 or the PK study, we found that methylone and MDC peaked early (Tmax=15-45 min) and were short lived (

37 rea-under-the-curve values for methylone and MDC were greater than dose-proportional, suggesting non-

38 atic biopsies which correlated with TARC and MDC expression and airway obstruction.

39 ess CCR4 and respond to its ligands TARC and MDC, whereas Th1 lymphocytes express CXC chemokine recep

40 (LPS)-induced production of MCP-1, TARC, and MDC by DCs was clearly enhanced.

41 covery of both recipient MDSCs (P < .01) and MDCs (P < .01) is significantly increased when the alkyl

42 Intermediate monocytes and MDCs were highly frequent in the airways compared with p

43 As a result, both PDCs and MDCs preferentially transmitted HIV-1 to the responding

44 Soon after HIV-1 exposure, both PDCs and MDCs were able to transfer the virus to T cells in the a

45 nocytes and B cells or unstimulated PDCs and MDCs.

46 rin domain of MDC-L was inhibited by an anti-MDC-L monoclonal antibody (mAb), Dis1-1.

47 CLP, and neutralization of the MDC with anti-MDC Abs decreased CLP-induced recruitment of peritoneal

48 A positive association was observed between MDC-associated IL-12 production and HCV-specific T cell

49 T cells conditioned with the B7-H1-blocked MDCs had a more potent ability to inhibit autologous hum

50 g IAV infection, we stimulated primary blood MDCs and inflammatory monocyte-derived DCs (MDDCs) with

51 TLR ligand was observed to enhance both MDC and PDC activation of naive CD4 T cells.

52 However, COX-2 regulation in both MDC populations differs from monocytes, as IL-4 does not

53 C express COX-1, but, unlike monocytes, both MDC populations constitutively express COX-2.

54 Both MDCs and PDCs were found to express the primary receptor

55 lone is extensively metabolized in rats, but MDC is the only centrally active metabolite that could c

56 4(+) T cells in a dose-dependent manner, but MDCs stimulated the highest frequencies of pp65-specific

57 resection is inhibited by gamma-H2AX and by MDC-1 (mediator of DNA damage checkpoint 1), which binds

58 action between RhoA and ROCK-2 is blocked by MDC and TGaseM, indicating a role for transglutaminase a

59 also up-regulates DC-SIGN gene expression by MDC.

60 IL-12 production and CD80/CD86 expression by MDC/PDC mixtures was further enhanced by CD40L and ISS-O

61 Further, second-wave aggregation induced by MDC in platelet-rich plasma was inhibited by aspirin, AD

62 JAK2, and this interaction was inhibited by MDC.

63 Endogenous PG production by MDC does not regulate CD40, CD80, CD86, or HLA DR expres

64 The release of TR6 by MDC was dependent on the activation of p42/p44 mitogen-a

65 n of GM3 and attenuation of virus capture by MDCs.

66 oprotein-pseudotyped lentivirus particles by MDCs were severely attenuated upon depletion of GSLs fro

67 esence or absence of mono-dansyl cadaverine (MDC), a TG inhibitor.

68 Our data implicate TSLP, TARC/CCL17, MDC/CCL22, and IP-10/CXCL10 in asthma pathogenesis.

69 s expressing mRNA encoding TSLP, TARC/CCL17, MDC/CCL22, and IP-10/CXCL10, but not I-TAC/CXCL11 and I-

70 mucosa expressing mRNA for TSLP, TARC/CCL17, MDC/CCL22, and IP-10/CXCL10, but not I-TAC/CXCL11 and I-

71 venance of TSLP, Th2-attracting (TARC/CCL17, MDC/CCL22, I-309/CCL1), and Th1-attracting (IP-10/CXCL10

72 erum concentration of CXCL10 (IP-10), CCL22 (MDC), CCL17 (TARC), CCL-2 (MCP-1) and CCL-13 (MCP-4) in

73 in the local chemokine production of CCL22 (MDC) and CCL17 (TARC), two chemokines previously shown t

74 uniformly suppressed the production of CCL22/MDC, a chemokine associated with infiltration of T regul

75 established that both CCR3/eotaxin and CCR4/MDC axes contribute to the recruitment of Th2 cells to t

76 the functional role of CCR3/eotaxin and CCR4/MDC during the in vivo recruitment of Th2 cells, we have

77 cells respond to both CCR3/eotaxin and CCR4/MDC pathways initially, but that a progressive increase

78 ells results in the predominance of the CCR4/MDC axis in the long-term recruitment of Th2 cells in vi

79 n results in the predominant use of the CCR4/MDC pathway.

80 After TLI/ATS + BMT, Gr-1(low)CD11c(+) MDCs and Gr-1(high)CD11c(neg) myeloid-derived suppressor

81 ude non-DCs, Lin(-)HLA-DR(+)CD11c(+)CD123(-) MDCs and Lin(-)HLA-DR(+)CD11c(-)CD123(+) PDCs were ident

82 prevented in mice with myeloid-derived cell (MDC)-specific deletion of TNFR1.

83 Freshly purified myeloid dendritic cells (MDC) and plasmacytoid DC (PDC) obtained from subjects wi

84 Myeloid, CD1a-sorted dendritic cells (MDC) productively replicated human immunodeficiency viru

85 nocytes and myeloid-derived dendritic cells (MDC) released the protein exclusively following stimulat

86 unction of monocyte-derived dendritic cells (MDC).

87 n of human CD11c(+) myeloid dendritic cells (MDCs) and CD123(+) plasmacytoid dendritic cells (PDCs),

88 od monocyte-derived myeloid dendritic cells (MDCs) express B7-H1, a member of the B7 family, on the c

89 capture of HIV-1 by mature dendritic cells (MDCs) is mediated by an interaction between the glycosph

90 ansion of recipient myeloid dendritic cells (MDCs) that induce contact-dependent expansion of donor T

91 By contrast, myeloid dendritic cells (MDCs) were absent from malignant ascites.

92 Monocyte-derived cells (MDCs), including professional antigen-presenting cells s

93 Microbial desalination cells (MDCs) are an emerging concept for simultaneous wastewate

94 Microbial desalination cells (MDCs) are an emerging concept for simultaneous water/was

95 eases in total leukocytes, Langerhans cells, MDC, LDC, and activated CD4+ T cells in draining lymph n

96 e receptor for macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC

97 Macrophage-derived chemokine (MDC) is a potent chemoattractant for antigen-specific T

98 tralization of macrophage-derived chemokine (MDC) with Ab caused a significant reduction of CCR4-posi

99 ine (TARC) and macrophage-derived chemokine (MDC)), CD (10 proteins), and PS (kynureninase (KYNU)).

100 tional role of macrophage-derived chemokine (MDC), a potent mononuclear cell chemoattractant, during

101 Macrophage-derived chemokine (MDC), a recently identified CC chemokine, has been regar

102 r (TNF)-alpha, macrophage-derived chemokine (MDC), and C10, known to enhance bacterial clearance.

103 ctor (GM-CSF), macrophage-derived chemokine (MDC), and macrophage inflammatory protein 1alpha (MIP-1a

104 kines, RANTES, macrophage-derived chemokine (MDC), macrophage inflammatory protein-1beta (MIP-1beta),

105 orted that the macrophage-derived chemokine (MDC), thymus activation-regulated chemokine (TARC), and

106 ; in addition, macrophage-derived chemokine (MDC), thymus and activation-regulated chemokine (TARC),

107 ta chemokines [macrophage-derived chemokine (MDC), thymus and activation-regulated chemokine (TARC),

108 t (MCP-1, MCP-5, monocyte-derived chemokine (MDC), thymus and activation-related chemokine (TARC), C1

109 ine (TARC) and macrophage-derived chemokine (MDC).

110 ands eotaxin and monocyte-derived chemokine (MDC).

111 e receptor for macrophage-derived chemokine (MDC).

112 10)/CXCL10 and macrophage-derived chemokine (MDC)/CCL22 production were evaluated at the mRNA or at t

113 (TARC)/CCL17, macrophage-derived chemokine (MDC)/CCL22, I-309/CCL1) and Th1-attracting (IFN-gamma-in

114 rine (EPI) and macrophage-derived chemokine (MDC, CCL22).

115 MCP-3/CCL7) or macrophage-derived chemokine (MDC/CCL22), elicited anti-gp120 antibodies with high tit

116 ARC/CCL17) and macrophage-derived chemokine (MDC/CCL22), which preferentially attract type 2 T helper

117 or CCL17), and macrophage-derived chemokine (MDC; or CCL22).

118 le protein-10, macrophage-derived chemokine [MDC], and platelet factor-4 [PF-4]) to be expressed by C

119 and CCL22 (or macrophage-derived chemokine; MDC), in Th2-type cytokine-dominated responses in the lu

120 o induces the secretion of the CC-chemokines MDC and TARC.

121 OX40L, the production of the Th2-chemokines MDC (macrophage-derived chemokine/CCL22) and TARC (thymu

122 These findings suggest that the chemokines MDC, TARC, and SDF-1, which may be produced during infla

123 ferent from that of secretion of chemokines (MDC, I-309, MIP-1alpha, MIP-1beta, and RANTES), cytokine

124 curacy and minimum detectable concentration (MDC).

125 ecular Probes]), autophagic vacuole content (MDC), SA-beta-galactosidase (FDG), and cathepsin activit

126 In contrast, MDC, but not SDF-1, lead to Ca(++) mobilization by plate

127 In contrast, MDCs, which express TLR3, TLR4, and TLR7, responded to p

128 that networks within multiple-demand cortex (MDC) become active when diverse skills and behaviors are

129 ing, networks within multiple-demand cortex (MDC), which control higher cognitive functions, such as

130 oebius syndrome minimum diagnostic criteria (MDC) (congenital, nonprogressive facial palsy, and abduc

131 ted that degrakines based on SDF-1 (CXCL12), MDC (CCL22) and RANTES (CCL5) specifically inactivate th

132 assays showed that SDF-1, which binds CXCR4; MDC, which binds CCR4; and ELC, which binds CCR7, mediat

133 Myeloid CD11c DC (MDC), which may have inflammatory functions, and plasmac

134 Myeloid CD11c+ DC (MDC), which may have inflammatory functions, and plasmac

135 ells (DCs), we evaluated myeloid-derived DC (MDC) and plasmacytoid-derived DC (PDC) frequencies and f

136 based on phenotypic markers: the myeloid DC (MDC) and the plasmacytoid DC (PDC).

137 three subsets, Langerhans cells, myeloid DC (MDC), and lymphoid DC (LDC), based upon phenotypic and f

138 macytoid DCs (PDCs) 40-fold and myeloid DCs (MDCs) 20-fold less frequent in HIV(+) nodes than in cont

139 c cells (DCs); CD11c(+)CD123(-) myeloid DCs (MDCs) and CD11c(-)CD123(+) plasmacytoid DCs (PDCs).

140 ecies of Lactobacillus on human myeloid DCs (MDCs) and found that they modulated the phenotype and fu

141 how different subsets of human myeloid DCs (MDCs) involved in tissue inflammation are affected by in

142 Myeloid DCs (MDCs) were identified as CD1c(+)CD11c(+)CD14(-)HLA-DR(+)

143 acytoid DCs (PDCs) and CD11c(+) myeloid DCs (MDCs) were susceptible to both a CCR5- and a CXCR4-using

144 rformed to identify mature DCs, myeloid DCs (MDCs), and plasmacytoid DCs (PDCs) by using antibodies a

145 ed subpopulations of monocytes, myeloid DCs (MDCs), and plasmacytoid DCs in the lung mucosa.

146 asmacytoid DCs (PDCs), CD11c(+) myeloid DCs (MDCs), monocytes, and B cells.

147 a biotin-independent malonate decarboxylase (MDC), which allows them to use malonate as the sole carb

148 The key to developing MDCs is to understand fundamental problems, such as the

149 We conclude that an elevated MDC:PDC ratio associates with early small bowel allograf

150 We conclude that an elevated MDC:PDC ratio associates with liver graft rejection, whi

151 Endogenous MDC was detected in the peritoneum after CLP, and neutra

152 Blockade of B7-H1 enhanced MDC-mediated T-cell activation and was accompanied by do

153 PDCs to augment angiogenesis while excluding MDCs to prevent angiogenesis inhibition, demonstrating a

154 Lactobacillus-exposed MDCs up-regulated HLA-DR, CD83, CD40, CD80, and CD86 and

155 conversion of MDSCs to PD ligand-expressing MDCs, and increased donor naturally occurring Treg recov

156 n pediatric control muscle, there were fewer MDCs than PDCs, and the distributions of MDCs and PDCs w

157 e critical producers of cytokines (IL-12 for MDC and type I/II IFNs for PDC) and are functionally dif

158 l 3-kinase, signaling pathways important for MDC maturation and survival.

159 this study that CCR4 is a major receptor for MDC and TARC on T lymphocytes, as anti-CCR4 mAbs signifi

160 press CCR4, the common specific receptor for MDC and TARC.

161 his study, we demonstrate a pivotal role for MDC during experimental sepsis induced by cecal ligation

162 on or the number of PDC, suggests a role for MDC in viral control.

163 e infiltrating lymphocytes, and staining for MDC was present on scattered individual cells throughout

164 Furthermore, MDC dramatically ameliorated CLP-induced systemic tissue

165 Furthermore, MDC-mediated capture and transmission of MA mutant virus

166 .004) was associated with numerically higher MDC counts and significantly lower PDC frequencies (P=0.

167 Among rejectors, a significantly higher MDC:PDC ratio (P=0.004) was associated with numerically

168 sures analysis showed a significantly higher MDC:PDC ratio (P=0.043, F-test) among rejectors, compare

169 Our data show that different human MDC subsets may play distinct roles during IAV infection

170 dulated the phenotype and functions of human MDCs.

171 I-MDC undergoing maturation with soluble CD40 ligand (sCD4

172 8 significantly reduces CD83 expression in I-MDC matured with sCD40L/IFN-gamma.

173 Immature MDC (I-MDC) and mature MDC express COX-1, but, unlike monocytes

174 Blocking COX-2 reduces I-MDC secretion of IL-12p40, whereas it increases IL-12p40

175 By immunohistochemistry, we identified MDCs throughout different anatomical locations of the lu

176 Immature MDC (I-MDC) and mature MDC express COX-1, but, unlike mo

177 COX-2-mediated PG production impacts MDC function as maturing these cells in the presence of

178 COX-2 is functional in MDC as a specific inhibitor, NS-398, significantly reduc

179 dds ratio, 0.79; adjusted P=0.03) but not in MDC.

180 arameters to achieve optimal desalination in MDCs.

181 Cells enriched in MDCs expressed CD86, moderate CD80, and little CD40, but

182 hese results suggest that TNFR1 signaling in MDCs is a critical mediator of both the detrimental and

183 IL-12 was sustained in MDCs exposed to all three Lactobacillus species in the p

184 ignificantly, however, mice lacking TNFR1 in MDCs succumbed to listeria infection, although they disp

185 conversion of LC3-I to LC3-II and increased MDC-labeled autophagic vacuoles.

186 upernatant collected from long-term infected MDC, which had been exposed to an X4R5 virus 45 days ear

187 Interestingly, MDC-mediated capture of Nipah and Hendra virus (recently

188 ce given the nonprotective immunogen had LDC:MDC ratios similar to those of naive mice.

189 Draining lymph node LDC:MDC ratios induced by the protective immunogen were sign

190 In conclusion, in the human lung MDCs were twice as numerous and expressed higher levels

191 We propose that this causal role makes MDC candidate target for experimental therapeutics; for

192 Immature MDC (I-MDC) and mature MDC express COX-1, but, unlike monocytes, both MDC popul

193 ases IL-12p40 and p70 production by maturing MDC.

194 our unrelated participants, also not meeting MDC, had large-angle exotropia, vertical gaze deficiency

195 Three percent of participants (3/112) met MDC but also had restricted vertical gaze.

196 The remaining 88 participants (79%) met MDC and had full vertical gaze.

197 I metabolites: 3,4-methylenedioxycathinone (MDC), 3,4-dihydroxy-N-methylcathinone (HHMC), and 4-hydr

198 Methylone, MDC, and HHMC were substrate-type releasers at monoamine

199 which was correlated with plasma methylone, MDC, and HHMC concentrations.

200 Treatment with monodansylcadarevine (MDC), a selective TGase inhibitor or down-regulation of

201 D Western blotting and monodansylcadaverine (MDC) staining to detect autophagic vacuoles.

202 which is inhibited by monodansylcadaverine (MDC; an inhibitor of transglutaminase activity) and TGas

203 s, the fluorescent dye monodansylcadaverine (MDC) and a green fluorescent protein (GFP)-AtATG8e fusio

204 h the TGase inhibitor, monodansylcadaverine (MDC), converted RA from a differentiation factor to an a

205 Cs in 0.3 M sucrose or monodansylcadaverine (MDC), which both inhibit clathrin-coated pit formation,

206 d p62, GFP-LC3 puncta, monodansylcadaverine (MDC) staining, and transmission electron microscopy.

207 effects, we found that monodansylcadaverine (MDC), which binds to the enzyme (transamidase) active si

208 to block tTG function (monodansylcadaverine; MDC) or c-Src kinase activity (PP2) disrupted the format

209 CD11c(+)CD14(-) lineage-negative (MDC-enriched) LAF cells were isolated and shown to be mu

210 Interestingly, MDDCs but not MDCs were protected against IAV infection after LPS (TLR

211 DC from HCV-infected persons, the ability of MDC to activate naive CD4 T cells in the presence or abs

212 ults indicate novel regulatory activities of MDC in innate immunity during sepsis and suggest that MD

213 Data were obtained from 163 cases of MDC and 6214 cases of non-Meckelian ileal cancer, betwee

214 e report here that the disintegrin domain of MDC-L is recognized by the leukocyte integrin alpha(4)be

215 roteins possessing the disintegrin domain of MDC-L supported adhesion of the T-lymphoma cell line, Ju

216 of Jurkat cells to the disintegrin domain of MDC-L was inhibited by an anti-MDC-L monoclonal antibody

217 N in the WKY rat, and whether the effects of MDC were dependent on its receptor CCR4.

218 mice resulting from transgenic expression of MDC resulted in acceleration of clinical disease.

219 the absolute number and median frequency of MDC in HIV-infected individuals were similar to those ob

220 Blocking the function of MDC did not affect the developing of the disease from da

221 Furthermore, in vitro HIV infection of MDC from normal subjects cultured with cocaine and/or HI

222 tion, mice treated with an i.p. injection of MDC cleared bacteria more effectively than those in the

223 The interaction of MDC-L with alpha(4)beta(1) may potentially regulate meta

224 tion is available concerning the presence of MDC in the kidney or their role in renal pathophysiology

225 lucrin levels accumulated in the presence of MDC.

226 ia, thereby identifying the opposing role of MDC TNFR1 in autoimmunity and bacterial infection.

227 secreted cytokines and chemokines typical of MDC upon stimulation with a TLR-4 agonist and both subse

228 atical model to simulate dynamic behavior of MDCs for the first time through evaluating multiple fact

229 data highlight the functional capacities of MDCs and PDCs in naive as well as healthy, infected maca

230 wer MDCs than PDCs, and the distributions of MDCs and PDCs were similar in pediatric control skin sam

231 Formation of MDCs requires the import receptors Tom70/71, and failure

232 ty and thus has highlighted the potential of MDCs as an energy-efficient technology to address water-

233 re was increased CD83 and CD86 expression on MDC from HCV-infected persons, the ability of MDC to act

234 GM3 on virus particles and CD169/Siglec-1 on MDCs.

235 Therefore, upregulation of B7-H1 on MDCs in the tumor microenvironment downregulates T-cell

236 rontal midline node of the cingulo-opercular MDC affected learning rates specifically during the init

237 RNA did not detect the presence of SDF-1 or MDC.

238 into a mitochondrial-derived compartment, or MDC, followed by release through mitochondrial fission a

239 n with recombinant RABV expressing GM-CSF or MDC protected significantly more mice against intracereb

240 ibody blocked aggregation induced by TARC or MDC.

241 er of the molecular family known as ADAMs or MDCs.

242 Optimally TLR ligand-stimulated PDCs or MDCs exposed to CMV or HIV-1 Ags enhanced autologous CMV

243 nsduced dendritic cells (DCs) overexpressing MDC would enhance the T cell-mediated humoral immune res

244 r malignancies and in 13% of these patients, MDC was the first malignancy.

245 ma production induced by AT-2 SIV-presenting MDC/PDC-enriched mixtures.

246 HLA DR expression; however, it does promote MDC maturation, as NS-398 significantly reduces CD83 exp

247 st, stimulation with TLR7/8 ligand protected MDCs but not MDDCs from IAV infection.

248 esent the crystal structure of a Pseudomonas MDC and give insights into its catalytic mechanism and f

249 ther investigated the binding of recombinant MDC-L disintegrin domain (rDis-Fc) in solution.

250 ons were observed in the replication sample (MDC).

251 al data from both a bench- and a large-scale MDC system.

252 on the nature of hepatitis; the data specify MDCs as the essential cell type of TNFR1 function in T c

253 iduals from the Malmo Diet and Cancer study (MDC) into baseline cystatin C quintiles (n=4757).

254 n=1015) and the Malmo Diet and Cancer Study (MDC; n=746).

255 TARC, MDC, and SDF-1 increased intracellular calcium concentra

256 latory T cells (Tregs) that express the TARC/MDC-specific chemokine receptor CCR4, thus generating an

257 a TLR-7 agonist by secreting IFN-alpha than MDC-enriched cells.

258 an allogeneic mixed lymphocyte response than MDC matured without this inhibitor.

259 10-fold more proinflammatory cytokines than MDCs upon ex vivo stimulation.

260 and male human participants to confirm that MDC was most active in the initial stages of learning a

261 These studies demonstrate that MDC express both COX isoforms constitutively and produce

262 This observation demonstrated that MDC activity is important for learning.

263 In this study, we also found that MDC activity on M omicron/M phi in this GN was at least

264 rating characteristic analysis revealed that MDC:PDC ratio more than or equal to 1.52 was associated

265 These results suggest that MDC is critically involved in the development of anti-GB

266 nate immunity during sepsis and suggest that MDC may aid in an adjunct therapy in sepsis.

267 al of malignant T cells and demonstrate that MDCs are abundant within the tumor microenvironment of T

268 The MDC and TARC receptor CCR4 was expressed on platelets, a

269 The MDC generated higher current with higher salt concentrat

270 The MDC model will be helpful with determining operational p

271 y was achieved for phantom inserts above the MDC of 1 MBq/mL.

272 dding from the plasma membrane to access the MDC-dependent trans infection pathway.

273 l bias based on measurements found below the MDC were recorded.

274 ongitudinal and cross-sectional cohorts, the MDC:PDC ratio was higher and was associated with decreas

275 ermore, optimal operating conditions for the MDC used in this study were estimated to have an acetate

276 When fed with 4 M NaCl, the MDC achieve a current density of 300 A m(-3) (anode volu

277 e inverse association with viral load of the MDC number, but not of IFN-alpha secretion or the number

278 itoneum after CLP, and neutralization of the MDC with anti-MDC Abs decreased CLP-induced recruitment

279 It was able to predict the response of the MDC with time under various conditions, and also provide

280 Additionally, recognition of the MDC-L disintegrin domain required "activation" of lympho

281 pression of the glomerular expression of the MDC/CCL22 chemokine and down-regulation of MIP-1alpha/CC

282 IL-12, but the effects are dependent on the MDC maturation state.

283 tochondrial dysfunction, suggesting that the MDC pathway provides protection to mitochondria in times

284 opose adding "full vertical motility" to the MDC for Moebius syndrome.

285 Adhesion of Jurkat cells to the MDC-L disintegrin domain was specifically inhibited by a

286 HIV-1 exposure of the MDCs and PDCs did not inhibit their ability to present c

287 In addition, an antagonist to MDC may represent a prime drug target for therapeutic ap

288 ntly inhibit the migration of these cells to MDC and TARC.

289 rthermore, adhesion of various cell lines to MDC-L correlated with expression of the integrin alpha(4

290 ide evidence that noninvasive stimulation to MDC nodes can enhance learning rates, thereby demonstrat

291 Herein, a tubular MDC was operated under a wide range of salt concentratio

292 pression of TLR4, TRIF, and MyD88 in the two MDC subsets regulated the ability of the cells to enter

293 In vitro, MDC enhanced the phagocytic and killing activities of pe

294 nd COX-2 when activated, we examined whether MDC express these enzymes and produce prostanoids that a

295 MP) following prostaglandin (PG) I(2), while MDC had no effect.

296 ncoding gp120 either alone or as fusion with MDC.

297 Treatment with MDC or TGase-1 siRNA decreased Stat-3 but not Akt phosph

298 rmines the ability of HIV-1 to interact with MDCs.

299 resent study demonstrated that a node within MDC, located in midline frontal cortex, becomes active d

300 these cells in the presence of NS-398 yields MDC that stimulate significantly more IFN-gamma in an al