ライフサイエンスコーパス: N terminus

1 domain during degradation initiated from the N terminus.

2 C terminus and a potential KH domain in its N terminus.

3 lytic domain in the C terminus of A3G to its N terminus.

4 ional states of the hydrophobic core and the N terminus.

5 cardiolipin via an amphipathic helix on its N terminus.

6 he N terminus and at 100 and 220 nm from the N terminus.

7 SdGluc5_26A and of a mutant truncated at the N terminus.

8 ved structural elements in the intracellular N terminus.

9 wice and is myristoylated at its cytoplasmic N terminus.

10 ATR-activating domain (AAD) located near its N terminus.

11 by N-methylation of the mature (pseudo)pilin N terminus.

12 two conserved Trp(1)-Cys(2) residues at the N terminus.

13 hydrophobic signal sequence near the protein N terminus.

14 at TF palmitoylation occurs primarily in the N terminus.

15 teolytic conditions in absence of the 20 kDa N-terminus.

16 identified an Snx3 sorting motif in the Neo1 N-terminus.

17 peptide retention when located closer to the N-terminus.

18 associated with processing bodies via their N-terminus.

19 idues at designed i and i+4 positions of its N-terminus.

20 n interacts, while Zn(2+) interacts near the N-terminus.

21 ached to cysteine has been introduced at its N-terminus.

22 of TRPM1, Gbetagamma interacts only with the N-terminus.

23 sidue at the C-terminus and a glycine at the N-terminus.

24 single leucine-rich repeat (LRR) within its N-terminus.

25 nes using an amphipathic helix at its unique N-terminus.

26 nto the flagella in the absence of the IFT46 N-terminus.

27 growth factor receptor at tyrosine 88 in its N-terminus.

28 ly dependent on the effector function of the N-terminus.

29 ed that FBXO32 physically interacts with the N-terminus (1-60 aa) of KLF4 via its C-terminus (228-355

30 eterminants within PopZ include 24 aa at the N terminus, a 32-aa region near the C-terminal homo-olig

31 Ubiquitination of GABARAP occurs in the N terminus, a domain associated with ATG8-family-specifi

32 ntified a nuclear export signal (NES) at the N terminus (AAs 176-192) that contributes to CASZ1 nucle

33 on, we define a critical region at the CASZ1 N terminus (AAs 23-40) that mediates the CASZ1b nuclear

34 ndings are consistent with a model where the N terminus acts as a lever to support amphetamine-induce

35 ed Lys-72 as an acetylation site in the ERK1 N terminus, adjacent to Lys-71, which binds to ATP, sugg

36 Our observations show that the N terminus affords the switch between transport modes.

37 ructural alterations that propagate from the N terminus all the way to the C terminus, without destab

38 he WCC and FRQ A V142G substitution near the N-terminus also alters FRQ and WCC binding to FRH, but p

39 ORRM4 contains an RRM domain at the N terminus and a Gly-rich domain at the C terminus.

40 s along the collagen type I molecule, at the N terminus and at 100 and 220 nm from the N terminus.

41 ils including pyroglutamic acid at the beta2 N terminus and bending within the EGF1 domain.

42 was observed in helix 1, which contains the N terminus and His-3, and has been associated with cogna

43 -length ARTEMIS resulted in unmasking of the N terminus and in increased ARTEMIS activity in cellular

44 ut also permissive communication of the Orai N terminus and loop2 in an isoform-specific manner.

45 To mimic interactions between the N terminus and loop2 in full-length Orai1 channels, we i

46 channels, we induced close proximity of the N terminus and loop2 via cysteine cross-linking, which a

47 Nesprin-2G engaged actin through its N terminus and microtubules through a novel dynein inter

48 main binds to two sites in Orai1, one in the N terminus and one in the C terminus.

49 o-transmembrane domain topology with a large N terminus and short C terminus oriented toward the outs

50 CXCL11 depends on the ACKR3 N terminus and some extracellular loop (ECL) positions f

51 d five basic residues distributed across the N terminus and the 30s and 50s loops of the chemokine do

52 opes governing the interaction between HuPrP N terminus and the second module of the NCAM fibronectin

53 sical interaction between the autoinhibitory N terminus and the TIR domain of SARM1, revealing a prev

54 eptor conserved disulfide bridge between the N terminus and TMVII is needed only for chemokines.

55 ase, which leads to the repositioning of the N terminus and transition to an inward-open state.

56 on of the ligand's ammonium group toward the N-terminus and (B) to the lack of a helical kink upon li

57 main were critical to recruitment, while the N-terminus and a functional ATPase domain played a minor

58 his weaker activation was mapped to the ETS2 N-terminus and a specific interaction with the co-repres

59 e demonstrate that substitutions at both the N-terminus and C-terminus of Cl-amidine result in >100-f

60 Mutations near the N-terminus and C-terminus of PZase were associated with

61 loops extending out the beta-barrel at both N-terminus and C-terminus, which is distinct to those of

62 ultiple residues in SMA clustered around the N-terminus and CDR loops experience considerable conform

63 This effect requires the N-terminus and coiled-coil domain (C-C) as mutations wit

64 the maltose binding protein (MBP) tag at the N-terminus and expressed it as a soluble protein in the

65 e (T) residues within the Presenilin 1 (PS1) N-terminus and in the large hydrophilic loop region sugg

66 d the WCC through interactions involving its N-terminus and KOW module.

67 nding domain is mediated by sequences in the N-terminus and mutations to this part of the protein hav

68 ARM1-specific inhibitors should focus on its N-terminus and predict that other PRMTs may employ simil

69 cial low-affinity interactions between Orai1 N-terminus and Stim1.

70 WT domain, dynamic flexibility occurs at the N-terminus and the first alpha-helix that connects the H

71 3-285] was formed by truncation of AP at the N-terminus and the minor catabolite [29-270] by truncati

72 7A at Tyr(334) (in the newly exposed deltaKD N terminus), and this (or an S359A substitution) rescues

73 djacent cluster of basic residues within the N terminus, and a potential network of salt bridges that

74 rafficking, depending on the presence of the N terminus, and differentially alter signaling to distin

75 se through a highly conserved motif at their N terminus, and mutation of this motif leads to their st

76 TF modulates the palmitoylation of TF at the N terminus, and palmitoylated TF is preferentially traff

77 alpha-helix in its aggregation-accelerating N terminus, and semi-rigid polyproline II helices in the

78 transport complex A binding to the TULP3/TUB N terminus, and subsequent release into PI(4,5)P2-defici

79 um and a homology model of the human tuberin N terminus are presented.

80 ved, truncated leucine zipper motif near the N terminus as well as a strictly conserved arginine resi

81 al analysis identified E17 within the PSD-95 N-terminus as important for binding to Ca(2+)/CaM by int

82 co-evolving regions, CENP-A L1 and the CAL1 N terminus, as critical for lineage-specific CENP-A inco

83 occupied N-linked glycosylation site at the N terminus at position 1 (equivalent to Asp-221 in the F

84 The extended Cdc3 N terminus autoinhibits Cdc3 association with Cdc10 homo

85 ation) "undocks" and repositions the cofilin N terminus away from the filament axis, which compromise

86 ich motif termed the P-motif, located in the N-terminus between serines 73 and 90, controls release o

87 Finally, we demonstrated that UL46 via its N terminus binds to STING and, via its C terminus, to TB

88 ghly basic amino acid residues either at the N-terminus (BMP2) or C-terminus (HA).

89 ty is due to residues in the bacterial cyt c N terminus, but the molecular basis is unknown.

90 hly conserved MacroD-type macrodomain at the N terminus, but the roles of nsP3 and the macrodomain in

91 About 70% of alpha2AP is cleaved at the N terminus by antiplasmin-cleaving enzyme (or soluble fi

92 and showed that VHL was first cleaved at the N-terminus by chymotrypsin C before being directed for p

93 in the C-terminal part of the extracellular N terminus can activate all GPHRs in vitro and in GPHR-e

94 CHMP7's N terminus comprises tandem Winged-Helix domains [6], an

95 The conserved cleavage site, close to the L2 N terminus, confounds observation and quantification of

96 ise manner, in which the individual domains (N terminus containing 17 amino acids (N17), polyQ, and p

97 DNedd4Lo has a unique N-terminus containing a Pro-rich region.

98 The N terminus contains an eag domain (eagD) that contains a

99 hat cognate metal binding to RcnR orders its N terminus, decreases helix 1 flexibility, and induces c

100 Deletion of the distal N-terminus (Delta2-135) accelerated off-gating current,

101 A truncation mutant lacking the N terminus (DeltaN) was found to alter TCL plasma membra

102 elta20 IFITM2) lacking 20 amino acids at the N terminus differentially restricts X4 and R5 HIV-1.

103 post-translational modifications on the UNG2 N-terminus disrupt formation of the PCNA-UNG2-RPA protei

104 in which the beta1 and beta2 strands of the N terminus domain of two adjacent monomers swap.

105 nded conformation with stable matrix-binding N-terminus, extended central array of 11 calcium-binding

106 inus facing the mitochondrial matrix and the N-terminus facing the intermembrane space.

107 I) first rapidly interacts reversibly at the N terminus followed by a slower, first order irreversibl

108 erminal domain positions the disordered MAD2 N-terminus for engagement by the TRIP13 "pore loops", wh

109 ed by the ubiquitin-proteasome system and an N-terminus fragment remains in the cytoplasm where it as

110 ential biomarker applications, electrophilic N-terminus functionalization is likely to impair GSH hom

111 y and egress, the late domain within the p12 N terminus functions to bind host vesicle release factor

112 Fusion of a small protein domain to the N terminus greatly facilitates direct visualization of t

113 to and exit from a CymA channel in which the N-terminus has been deleted.

114 (ZnCl2) and the subsequent immobilization of N-terminus his-tagged peptide, NFO4.

115 ance by binding in the aqueous pore near the N-terminus, however, significantly modifies the tetramer

116 In contrast, CIA2A bound to viperin's N terminus in a CIA1-, CIA2B-, and MMS19-independent fas

117 ing 50 commencing with amino acids MG at the N-terminus in one or more of the T. cruzi genomes.

118 Substitution of the N-terminus in the most potent compound for a more solubl

119 Ordering of the ArfA N-terminus in the second state rearranges RF2 into an ex

120 with fast-exchanging segments located in the N terminus, in helix 1 (residues 14-24), and at the C te

121 expressed in somatic cells, which lacks the N terminus including the CXXC domain, a DNA-binding modu

122 eta1AR at five residues in the extracellular N terminus, including the Ser-49 residue at the location

123 Biochemical assays confirm that the Cut7 N terminus increases Cut7 occupancy by binding directly

124 lar path in conjunction with protease domain N terminus insertion, suggesting a more complete molecul

125 We show that S2's extended N terminus inside the tunnel is converted into a helix b

126 Here we show that the TSC2 N terminus interacts with the TSC1 C terminus to mediate

127 HABP2, suggesting impaired insertion of the N terminus into the G221E protease domain, with a concom

128 ain could sterically hinder insertion of the N terminus into the HABP2 protease domain, helping to ex

129 PDZ (PSD-95/Dlg/ZO-1) domain located at its N terminus involved in subcellular targeting.

130 eting ADAPT6 labeled with radiometals at the N terminus is able to image HER2 expression in xenograft

131 onclusion, the conserved portion of the Orai N terminus is essential for STIM1, as it fine-tunes the

132 ored C terminus, whereas the surface-exposed N terminus is highly variable, a feature used for identi

133 , the main coupling site for STIM1, the Orai N terminus is indispensable for Orai channel gating.

134 wed that in stably transformed plants, Toc75 N terminus is located on the intermembrane space side, n

135 acidic residues Asp and Glu near the peptide N-terminus is by far the most prominent among them.

136 vity of SWR, whereas an acidic region at the N-terminus is required for optimal SWR function.

137 acid residues and an anionic pyranine at the N-terminus is triggered upon addition of a supramolecula

138 work on PNAs fluorinated in backbone and at N-terminus, it is evident that the fluorinated PNAs have

139 becomes more efficient after removal of the N terminus, leading to faster crosslinking of alpha2AP t

140 tended polyglutamine (polyQ) sequence at the N terminus leads to neuronal degeneration both in a cell

141 um pharmacophore and its modification at the N-terminus leads to selective KOR antagonists.

142 of GAPDH1 with the cortex is mediated by the N-terminus, likely palmitoylation.

143 tep in pore formation, mediated by the nisin N-terminus-lipid II pentapeptide hydrogen bond.

144 We propose that the UNG2 N-terminus may serve as a flexible scaffold to tether PC

145 show that WRN possesses two KBMs; one at the N terminus next to the exonuclease domain and one at the

146 The amino- (N-) terminus (Nt) of a protein can undergo a diverse arr

147 We conclude that the IFT46 N-terminus, ODA16, and outer arm dynein interact for IFT

148 brillize, deletions of ten residues from the N terminus of Abeta have little impact on its ability to

149 e activity produces Cys-sulfinic acid at the N terminus of an ERF-VII peptide, which then undergoes e

150 e findings shed light on the function of the N terminus of BRCA2 and have implications for the evalua

151 Here, we identify a region in the N terminus of BRCA2 that exhibits DNA binding activity (

152 ored RII subunits directing the myristylated N terminus of catalytic subunits toward the membrane for

153 Including a palmitoylation motif at the N terminus of CaV2.2 I-II loop was insufficient to targe

154 cated in the membrane-proximal region of the N terminus of chECL1, suggesting that the binding site o

155 Here we show that the N terminus of CHMP7 acts as a novel membrane-binding mod

156 RPK1 interacts with an RS-like domain in the N terminus of CLK1 to facilitate the release of phosphor

157 Here we demonstrate that the N terminus of E3 is necessary to inhibit an IFN-primed v

158 The N terminus of Ets-1 interacts with a part of the ERK2 D-

159 We conclude that the N terminus of F1L is not involved in apoptosis inhibitio

160 udies indicate that the beta-9 sheet and the N terminus of FGF14 are well positioned targets for drug

161 Within the complex, the N terminus of FLASH interacts with the N terminus of the

162 bodies reacted with linear epitopes near the N terminus of gH, exhibited strain specificity, and neut

163 luTR-binding protein (GBP) interact with the N terminus of GluTR Loss-of function mutants of ClpR2 an

164 phosphodiester backbone of bound DNA and the N terminus of helix H1.

165 ificity of the PHD domain for the unmodified N terminus of histone H3 and of the BRD domain for H3 ac

166 inker, which resemble the positively charged N terminus of histone H3, reduce the binding affinity of

167 fusing an extra phluorin-tagged helix to the N terminus of human Kv7.3.

168 Overexpression of the N terminus of mammalian homologue of Drosophila Pins (LG

169 owever, when a GFP moiety is appended to the N terminus of MJ0366, ClpXP releases intact GFP with a 4

170 e pan-opioid sequence Tyr-Gly-Gly-Phe at the N terminus of most endogenous opioid peptides (EOPs).

171 3 is important for Top2 to interact with the N terminus of Mus101, which contains the BRCT1/2 domains

172 t exploits the scaffolding properties of the N terminus of p120RasGAP to tightly regulate netrin-1/DC

173 iption, suggesting that the highly conserved N terminus of PilA was the regulatory signal.

174 he binding of a novel conserved motif in the N terminus of PilM, and binding PilN abrogates this bind

175 PilM binds to the N terminus of PilN, and we hypothesize that this interac

176 omponents in the cavity of hexon-the cleaved N terminus of precursor protein VI (pVIn), the cleaved N

177 of precursor protein VI (pVIn), the cleaved N terminus of precursor protein VII (pVIIn2), and mature

178 covalent attachment of myristic acid to the N terminus of proteins in eukaryotic cells.

179 serovar Typhimurium displaying the variable N terminus of PspA (alpha1alpha2) for intranasal vaccina

180 The zf-MYND-like domain at the N terminus of rice CCR4 and the PXLXP motif of rice CAF1

181 Since the N terminus of S2 is initially in an extended conformatio

182 edox active cysteine pair C52 and C57 in the N terminus of Sil1 results in the Doa10-dependent ERAD o

183 CML36 interacts directly with the regulative N terminus of the Arabidopsis plasma membrane Ca(2+)-ATP

184 Conserved basic residues at the N terminus of the channel are important for activation b

185 ,5-bisphosphate (PtdIns(3,5)P2) binds to the N terminus of the channel-distal from the pore-and the h

186 monstrated that Oct1p directly processes the N terminus of the CoQ-related methyltransferase, Coq5p,

187 creasing sarcomere length or by deleting the N terminus of the cRLC.

188 hat clamps the internal fusion loop with the N terminus of the ebolavirus glycoproteins (GPs) and pot

189 prising 15 to 20 hydrophobic residues at the N terminus of the Env-gp41 subunit, is a critical compon

190 In the presence of ceramide, the N terminus of the first transmembrane domain of TM4SF20

191 f prior to secretion by the pathogen and the N terminus of the mature effector was found likely to be

192 nto an array without any need to protect the N terminus of the peptide.

193 g possible distinct regulatory roles for the N terminus of the protein.

194 ote cohesion is mediated by sequences in the N terminus of the protein.

195 hat the Salmonella adaptor ClpS binds to the N terminus of the regulatory protein PhoP, resulting in

196 er demonstrate that a conserved motif at the N terminus of the ruler protein interacts with the T3SS

197 ing for envelope (Env) protein segments: the N terminus of the surface subunit and the cytoplasmic ta

198 , the N terminus of FLASH interacts with the N terminus of the U7 snRNP protein Lsm11, and together t

199 These data demonstrate that the N terminus of the VACV E3 protein prevents DAI-mediated

200 e topology of the VEGF-binding domain at the N terminus of VEGFR2.

201 C2 phosphorylates serine 26 at the cytosolic N terminus of xCT, inhibiting its activity.

202 ce, and two partial gamma rotations lock the N terminus of zeta in an "inhibition-general core region

203 he enzyme first removes 10 residues from the N-terminus of a 35-residue substrate.

204 The N-terminus of a precursor peptide (BtmD) is converted in

205 attached the complementary DNA strand to the N-terminus of a protein.

206 es a central tryptophan within SST14 and the N-terminus of Abeta1-42.

207 reduces conformational heterogeneity at the N-terminus of alpha1 but does not affect structure at th

208 Finally, we demonstrate that the N-terminus of CARM1 is involved in substrate recognition

209 ive deaminase domain, presence of CD1 on the N-terminus of CD2 enhances the deaminase activity by ove

210 ensitive cysteine and lysine residues within N-terminus of channel protein.

211 t the C-terminus of aspartic acid and at the N-terminus of cysteine.

212 oses, and that specific amino acids near the N-terminus of DnaC interact with a site in DnaB's C-term

213 Thus, the N-terminus of DPPA3 has a significant role in cytoplasmi

214 terminal domain and its interaction with the N-terminus of eRF3a.

215 single chain variable fragment (scFv) at the N-terminus of gD failed to mediate entry, even though th

216 We found that the N-terminus of gD tolerates long insertions, whereas resi

217 By tethering these proteins to the N-terminus of GLUT1 and performing saturation BRET analy

218 tance of various modes of interaction of the N-terminus of hDAT in controlling the pathways of releas

219 en a functional hotspot on ubiquitin and the N-terminus of histone H2A.

220 lipids are extracted from the bilayer by the N-terminus of IAPP, and integrated into amyloid aggregat

221 The N-terminus of IQGAP1 associated with the C-terminus of I

222 Moreover, the N-terminus of LIMCH1 binds to the head region of NM-IIA.

223 The N-terminus of MerA is able to extract the bound Pb(VI) b

224 The N-terminus of MLL and MLL-fusions form a complex with le

225 An Ile1Trp mutation of the N-terminus of nisin has been modelled and docked onto li

226 signalling by identifying a C2 domain at the N-terminus of Notch ligands, which has both lipid- and r

227 To understand the importance of the N-terminus of Orb2A and its relation to the fibril core,

228 These data show that the N-terminus of Orb2A not only promotes the formation of f

229 n transduction domain (PTD) was fused to the N-terminus of p38.

230 t cleave single amino acid residues from the N-terminus of peptide substrates.

231 a(2+)/calmodulin (Ca(2+)/CaM) binding to the N-terminus of PSD-95 mediates postsynaptic loss of PSD-9

232 r, we report that 3E10 directly binds to the N-terminus of RAD51, sequesters RAD51 in the cytoplasm,

233 r protein processing and secretion, with the N-terminus of radical fringe (a Golgi-resident protein).

234 ts revealed that the Mynd-like domain at the N-terminus of rice CCR4 proteins and the PXLXP motif at

235 ore, we show that INPP5E associates with the N-terminus of RPGR and trafficking of INPP5E to cilia is

236 Adding a transmembrane anchor to the N-terminus of Sec17 bypasses this requirement for apolar

237 in which a single Ub moiety is fused at the N-terminus of SMN(K0) and thereby mimicking SMN monoubiq

238 In vitro studies showed the acidic N-terminus of Swc5 preferentially binds to the H2A-H2B d

239 The N-terminus of the A isoform (Orb2A) that precedes its Q-

240 els in the intermembrane space are high, the N-terminus of the amphipathic alpha-helix is bound to a

241 tion function-1 (AF-1) domain located in the N-terminus of the androgen receptor (AR) is an attractiv

242 diated loss of inhibitory domains within the N-terminus of the BRAF protein.

243 olving beta-carbon attack at the much harder N-terminus of the gamma-glutamyl (Glu) unit of GSH.

244 A disordered region at the N-terminus of the glucocorticoid receptor can fine tune

245 for GLP-1R, GCGR, and GIPR were fused to the N-terminus of the heavy chain or light chain of an antib

246 The region around the N-terminus of the heavy chain, the Na(+)-binding loop, a

247 panded polyglutamine (polyQ) domain near the N-terminus of the huntingtin (htt) protein.

248 n and bind to a basic region adjacent to the N-terminus of the kinase.

249 yotes and occurs co-translationally when the N-terminus of the nascent polypeptide is still attached

250 main 2 (Ubl2) is immediately adjacent to the N-terminus of the papain-like protease (PLpro) domain in

251 Positioning the aromatic units close to the N-terminus of the peptide backbone near the hydrophobic

252 s formed by an isopeptide bond attaching the N-terminus of the peptide to a side chain carboxylate.

253 cular interactions involving the hydrophilic N-terminus of the peptide, and water-mediated interactio

254 sense EIF1AX mutations were clustered at the N-terminus of the protein in a region associated with it

255 iodurans membrane fraction suggests that the N-terminus of the protein interacts with the membrane.

256 enzyme N-myristoyltransferase to modify the N-terminus of the protein of interest with an azido fatt

257 Treatment with recombinant domain 1, 1+2 (N terminus), or 4 (C terminus) independently activated m

258 es in protoplasts revealed that, with a free N terminus, PGD1 and PGD3 accumulate in the cytosol and

259 roteins and the PXLXP motif at the rice CAF1 N-terminus play critical roles in OsCCR4-OsCAF1 interact

260 proteins as a putative binding site; 3) the N-terminus rather than the C-terminus occupies the site

261 connected by a flexible linker, whereas the N-terminus remains unstructured.

262 ays a major role in aggregation, whereas the N-terminus retains most of its solvent-accessibility dur

263 tides with an (S)-beta-Caa(l) monomer at the N-terminus revealed a right-handed 10/12-mixed helix.

264 e peptide backbone structure, the protonated N-terminus serves to stabilize the beta-hairpin by posit

265 When bound to CaM, the probe nearest RyRp's N-terminus shows rapid rotational motion consistent with

266 , we found that the 2nd position towards the N-terminus side of the HA PCS (P2 position) avoided hydr

267 At its N terminus, SLP-76 has three key tyrosines (Tyr-113, Tyr

268 lobular parts in the absence of the flexible N terminus, specifically the hydrophobic domain (HD) or

269 g excited state ensemble was an unstructured N-terminus stabilized by non-native contacts in a confor

270 s consistently replaced: one at the envelope N terminus that alters receptor choice and one in the R

271 protein, which share a conserved hydrophobic N terminus that is a curved extended alpha-helix, alpha1

272 ced bulky hydrophobic nature to the AbetapE3 N terminus that might explain the enhanced aggregation p

273 Key molecular determinants within the Orai N terminus that together with STIM1 maintained the typic

274 One isoform, Orb2A, has a unique N-terminus that has been shown to be important for the f

275 t it is the protonation/deprotonation of the N-terminus that is responsible for the switch with pH.

276 nhanced toxicity in Alzheimer's disease: the N-terminus, the central salt bridge, and the C-terminus.

277 phorylated on two specific residues near its N terminus, then binds to the F-box protein 3 (FBXO3) E3

278 e metal binding altered flexibility from the N terminus through helix 1 and modulated the RcnR-DNA in

279 ive aromatic cage in one Fab and the histone N terminus to a pocket in the other, thereby rationalizi

280 W41 ensures proton conduction only from the N terminus to the C terminus and prevents reverse curren

281 3T cells, FRET efficiencies from the alpha1S N terminus to the II-III and III-IV loops and the C-term

282 irA, a protein that utilizes residues in its N-terminus to directly target Domain I of the bacterial

283 tiple locations, including the extracellular N-terminus, transmembrane domains, and transmembrane 3-t

284 In addition, linkage in the mobile Bak N-terminus (V61C) specifically quantified association be

285 sing membranes: in the absence of Na(+), the N terminus was rapidly digested.

286 -specific dsDNA binding protein Sso7d in the N-terminus was designed.

287 ADAPT6, having the (HE)3DANS sequence at the N terminus were produced and site-specifically labeled u

288 riant far more rapidly when pulling from the N terminus, whereas translocation speed is reduced only

289 e available for Sirt1 and exploit its unique N-terminus, whereas drug-like activators for Sirt2-7 are

290 ined by the efficiency of proteolysis of the N terminus, which is regulated by allosteric binding sit

291 depends on a proline-rich sequence near the N terminus, which is unique among HOX genes and highly c

292 bly activated by proteolytic cleavage of the N terminus, which unmasks a tethered peptide ligand that

293 This efflux was proposed to rely on the N terminus, which was suggested to adopt different confo

294 urface of the beta1AR, but the extracellular N-terminus, which is a target for post-translational mod

295 s with drastically different conformation of N-terminus, which is also a key difference between Dark

296 between the DRVIA7 light-chain CDR1 and the N terminus with N276 and V5 glycans of gp120.

297 Replacing the DAT N terminus with that of SERT had no effect on DA transpo

298 tors is driven by interaction of the peptide N terminus with the receptor core.

299 that is initiated by interaction of the ICP0 N-terminus with PML.

300 show that DPP9 cleaves Syk to produce a neo N-terminus with serine in position 1.