ライフサイエンスコーパス: N-terminally

1 cetylase (Nt-acetylase) and therefore cannot N-terminally acetylate a majority of normally N-terminal

2 lpha-synuclein (alphaS) has been shown to be N terminally acetylated in its physiological state.

3 Although many eukaryotic proteins are amino (N)-terminally acetylated, structural mechanisms by which

4 strated that the physiological form of AS is N-terminally acetylated (AcAS).

5 (Met) residue of a nascent protein is often N-terminally acetylated (Nt-acetylated).

6 the acetylated proteins yields a mixture of N-terminally acetylated (true N-terminal) and non-acetyl

7 Furthermore, the novel BOG-bound state of N-terminally acetylated alpha-synuclein may serve as a m

8 has an N-terminal amphipathic helix that is N-terminally acetylated and mediates association with th

9 le from those recorded for the corresponding N-terminally acetylated and nonacetylated 15-residue syn

10 We obtained curated N-terminally acetylated and unacetylated sequences from

11 Thus, the naturally occurring N-terminally acetylated form of alpha-synuclein exhibits

12 ilure of Der1, a Hrd1 complex subunit, to be N-terminally acetylated in NatB mutant yeast.

13 cal oligomeric forms of alpha-synuclein, the N-terminally acetylated protein adopts a novel conformat

14 -terminally acetylate a majority of normally N-terminally acetylated proteins, including Hsp90 and mo

15 We chemically synthesized the N-terminally acetylated psoriasin of 100 amino acid resi

16 , for which data could not be obtained, were N-terminally acetylated, and all beta-crystallins lacked

17 Parkinson disease protein alpha-synuclein is N-terminally acetylated, but most in vitro studies have

18 lpha-syn from Escherichia coli, which is not N-terminally acetylated.

19 d that the native and expressed proteins are N-terminally acetylated.

20 e prepared by solid phase synthesis and were N-terminally acylated with 6-azidohexanoic acid.

21 N-terminally anchored constructs tethered only if the C

22 Cytochromes P450 are monotopic hemoproteins N-terminally anchored to the ER membrane with their prot

23 , we generated T7 phage display libraries of N-terminally and C-terminally truncated FGF-BP1 fragment

24 Complexes containing a series of N-terminally and C-terminally truncated Swr1 subunits re

25 mer's disease-associated fragment of APP, is N-terminally arginylated in the brains of 5xFAD mice and

26 molecules in which this core region extends N-terminally as far as to residue approximately 145, and

27 We then synthesized N-terminally biotinylated peptidyl phosphonates to ident

28 ubiquitination, we generated lysine-less and N-terminally blocked versions of one substrate, the poly

29 be2w can ubiquitinate a lysine-less, but not N-terminally blocked, ataxin-3.

30 dentify a heretofore unknown modification-an N-terminally bound glyoxylyl group-in the poorly charact

31 mponent RcoM transcription factor couples an N-terminally bound heme cofactor with a C-terminal "LytT

32 icelles, the transmembrane domain is flanked N-terminally by an alpha-helix that forms a ring around

33 expressing Foxp3 species engineered to mimic N-terminally, C-terminally, or N- and C-terminally cleav

34 f a H-bond observed in crystal structures of N-terminally capped peptides.

35 The N-terminally cleaved Bim(EL) became hyperactive in induc

36 nship between cellular SUMO-modified Sp1 and N-terminally cleaved Sp1.

37 lude hyperphosphorylated, ubiquitinated, and N-terminally cleaved TDP-43.

38 ally ubiquitinated, hyperphosphorylated, and N-terminally cleaved to generate C-terminal fragments (C

39 In vivo Sp1 was determined to be N-terminally cleaved, while Sp1(K16R) could not be cleav

40 We previously discovered that an N-terminally-cleaved form of RXRalpha (tRXRalpha), produ

41 shaped dimer in the apo state and a twisted, N-terminally closed dimer with ATP.

42 cation of the minority of clones that encode N-terminally-complete proteins.

43 ataset resulted in the identification of 352 N-terminally-complete, putative secreted proteins.

44 e consistent with the destabilization of the N-terminally coordinated structure due to the increasing

45 In contrast to several other N-terminally deleted forms of PrP, the C1 fragment does

46 on is highlighted by the observation that an N-terminally deleted mutant of RalGDS that retains the a

47 PG deletion mutants restored adhesion, only N-terminally deleted PG, but not C-terminally deleted PG

48 dence indicates that DeltaNp63 proteins, the N-terminally deleted versions of p63, are essential for

49 o circumvent this problem, multiply charged, N-terminally derivatized peptides were subjected to elec

50 e position, and in polyubiquitin chains, the N-terminally derived fragments from each constituent mon

51 f these co-chaperones bind preferentially to N-terminally dimerized Hsp90, the buffering effect of th

52 PDAPP transgenic mice were treated with the N-terminally directed 3D6 antibody, whereas mice treated

53 Thus, these N-terminally directed antibodies can differentially reco

54 yses demonstrated that the 3D6 and 10D5, two N-terminally directed antibodies, bound with high affini

55 To resolve this paradox, N-terminally epitope-tagged beta and beta' were expresse

56 Activator BH3s remain associated with the N-terminally exposed BAX through the BH1 domain to drive

57 Novel exon 1 protein-coding regions N-terminally extend human KCNE3 and KCNE4.

58 After recently uncovering novel, N-terminally extended (L) KCNE3 and KCNE4 isoforms and d

59 eoprotein (NP) 383-391 epitope is made as an N-terminally extended 14-mer before it is trimmed by ERA

60 ulation was elicited with specificity for an N-terminally extended epitope.

61 However, N-terminally extended forms of Abeta (NTE-Abeta) were re

62 analyses of mouse brain extracts identified N-terminally extended forms of Hp containing either thre

63 f oxyntomodulin, GLP-1, truncated GLP-1, and N-terminally extended GLP-2.

64 ERAP1 and ERAP2 heterodimers (ERAP1/2), and N-terminally extended model and natural peptides in thei

65 However, mutant N-terminally extended peptides exhibited significantly i

66 ass spectrometry approach, a whole family of N-terminally extended peptides in addition to RVD-Hpalph

67 ; however, such binding is not restricted to N-terminally extended peptides, suggesting that the resu

68 ction of the mutgp100209-217 epitope and its N-terminally extended peptides.

69 (hsp60) molecule that has been shown to bind N-terminally extended precursors of OVA-derived SIINFEKL

70 postproteasomal step: hsp90 associates with N-terminally extended precursors of the SIINFEHL epitope

71 ion, this treatment induced the synthesis of N-terminally extended proteins and elevated stop codon r

72 ed the larger molecular weight isoform as an N-terminally extended SK2 protein.

73 ian aspartic protease, is also stimulated by N-terminally extended substrates.

74 matic capabilities of different truncated or N-terminally extended variants of nsP2 revealed that the

75 nucleation, elongation) are reduced for the N-terminally extended variants.

76 a wider CD8(+) T cell response also towards N-terminally extended versions of the minimal epitope.

77 We called the N-terminally extended XLalphas extra-extra-long Gsalpha,

78 sfected bovine aortic endothelial cells with N-terminally FLAG-tagged MGP and used immunoprecipitatio

79 g the protease with 4 residues (SFNF) of its N-terminally flanking sequence in the Gag-Pol precursor

80 N-terminally formylated signal peptide fragments with va

81 g effect of Arg(19) substitution propagating N-terminally from position 19 to the pentaglycine linker

82 region of F1L spanning residues 1-50 located N-terminally from the Bcl-2 fold is an intrinsically uns

83 C-terminally fused (gp20-GFP, gp20-HOC) and N-terminally fused (GFP-gp20 and HOC-gp20) portal fusion

84 mutation in dfer (dfergof) that expresses an N-terminally fused form of the protein, similar to oncog

85 ic yellow fluorescent protein (mCitrine) was N-terminally fused to a small (approximately 6 kD) membr

86 ue light photoreceptor domain, PYP, which is N-terminally fused to the bacteriophytochrome domain (Bp

87 zed as preproteins, carrying signal peptides N-terminally fused to their mature domains.

88 f enhanced green fluorescent proteins (eGFP) N-terminally fused with KISD in HEK293T cells indicates

89 aliana ARF1, and find that the half-lives of N-terminally HA-tagged ARF1 and C-terminally luciferase-

90 A purified N-terminally hexahistidinyl-tagged AtPCS1 truncate conta

91 oxygenase was purified as a stable colorless N-terminally His-tagged protein.

92 The crystal structure of the N-terminally histidine-tagged epoxidase component of thi

93 a small residue preceding the cleavage site N-terminally (i.e., at the P1 position) and a hydrophobi

94 N-terminally labeled proteins can be selectively conjuga

95 Real-time changes in FRET between N-terminally labeled SNAP-25 and VAMP reported a reorien

96 ariant of an evolved sortase A (SrtA 7M) was N-terminally labeled with lithocholic acid (LA)-an inexp

97 Cleavage yielded 12 N-terminally labelled GAP-43 fragments that could be res

98 eins that are anchored to a cell membrane by N-terminally linked fatty acids.

99 The artificial beta-sheet consists of two N-terminally linked peptide strands that are linked with

100 owever, while NudC and NudCL dimerize via an N-terminally located coiled coil, the smaller NudCL2 lac

101 ing A1 domain of VWF is connected to the VWF N-terminally located D'D3 domain through a relatively un

102 ally located transmembrane helix and in more N-terminally located helices can be detected already at

103 The N-terminally longer proteins may play regulatory roles.

104 All fungal and animal N-terminally methylated proteins contain a unique N-term

105 ainly composed of intact ADan-(1-34) and its N-terminally modified (pyroglutamate) counterpart togeth

106 eceptor (PTHR) are N-terminally truncated or N-terminally modified analogs of PTH(1-34) or PTHrP(1-34

107 zed using the L209A mutant of P450 2B1 in an N-terminally modified construct with a C-terminal His ta

108 ircumvent these problems, two novel acylated N-terminally modified GIP analogues, N-pGluGIP(LysPAL(16

109 f the nitroxide when compared to that of the N-terminally modified Proxyl-Gtalpha(340-350) analogue.

110 However, PFA1 binds the toxic N-terminally modified pyroglutamate peptide pyro-Glu3-Ab

111 vitro was drastically decreased for both the N-terminally mutated and dimethylated variants, and both

112 Immunological analyses using an N-terminally myc-tagged mK44 construct demonstrated endo

113 Membrane targeting is mediated by the N-terminally myristoylated matrix (MA) domain of Gag and

114 l-(4,5)-bisphosphate (PI(4,5)P(2)) and Gag's N-terminally myristoylated matrix (MA) domain.

115 dependent on calcium and is mediated by the N-terminally myristoylated matrix (myr(+)MA) domain.

116 (3) N-Terminally myristoylated NCS-1 dimerizes in a calcium-

117 e stages of the HIV-1 replication cycle, the N-terminally myristoylated p17 domain targets the Gag po

118 ic cleavage in mu1 allows the release of its N-terminally myristoylated peptide, mu1N (4 kDa), which

119 Previous findings showed that N-terminally myristoylated peptides constituting a recep

120 In most retroviruses, retroviral MAs are N-terminally myristoylated.

121 an inhibitory segment that flanks the kinase N-terminally (N-linker) and that acts synergistically wi

122 tigated systems, nucleotides can bind to the N-terminally open and closed state without strictly forc

123 during cerebellar development, and identify N-terminally phosphorylated c-Jun as an important substr

124 ein levels of the Fbw7 substrates Notch1 and N-terminally phosphorylated c-Jun were upregulated in fb

125 Bag1-L preferentially interacts with N-terminally phosphorylated c-Jun, and Bag1-L greatly au

126 Here we show that unphosphorylated, but not N-terminally phosphorylated c-Jun, interacts with Mbd3 a

127 the transcription factors active Notch1 and N-terminally phosphorylated c-Jun.

128 We show that axin, APC2, GSK-3beta and N-terminally phosphorylated forms of beta-cat can locali

129 NAc-O-Thr, whereas ppGalNAc T3 and T6 prefer N-terminally placed GalNAc-O-Thr.

130 rthermore, the findings demonstrate that the N-terminally placed signaling helix domain is not requir

131 For N-terminally placed tags, lipophilicity promoted liver u

132 nd specifically to telomeric DNA using their N-terminally positioned myb-like domain of the same type

133 psid protein and the scaffolding protein are N-terminally processed in both 80alpha and SaPI1 procaps

134 rozoite invasion, we show that native CSP is N-terminally processed in the mosquito host and undergoe

135 lular LOXL2 (~75-kDa) is nonglycosylated and N-terminally processed, and is primarily associated with

136 s study, we show that the ATPase activity of N-terminally purified Drs2p associates primarily with a

137 Extending mutagenesis N-terminally revealed a second functionally critical reg

138 e additionally use CRISPR/Cas9 technology to N-terminally tag Rab8, which is then used to address end

139 D into bacterial or mitochondrial membranes, N-terminally tagged AIF and AMID displayed substantial N

140 Overexpressing N-terminally tagged AIF and AMID enhanced the growth of

141 tagged AIF and NADH-binding site mutants of N-terminally tagged AIF and AMID failed to show both NAD

142 prisingly found that the redox activities of N-terminally tagged AIF and AMID were sensitive to roten

143 While the N-terminally tagged ICP27 virus behaved like wild-type H

144 SP5 dramatically increased the solubility of N-terminally tagged NSP5 and prevented NSP5 hyperphospho

145 , GFP fluorescence, and activity relative to N-terminally tagged Rem (GFPRem).

146 Moreover, after SigT was N-terminally tagged with 3xFLAG and C-terminally tagged

147 ly-UBQ gene encoding ubiquitin (Ub) monomers N-terminally tagged with hexahistidine.

148 proteoliposomes reconstituted with purified, N-terminally TAP-tagged Drs2p, both ATPase and flippase

149 btained by prior host-guest techniques or in N-terminally templated helices and peptides bearing long

150 interacts with Mcm1p through a motif located N terminally to its homeodomain.

151 bait of wild-type small T antigen (sT) fused N terminally to the DNA-binding domain of Gal4.

152 n physiologic substrate for APCE, is cleaved N-terminally to Asn-alpha(2)AP that is rapidly cross-lin

153 protein fusion consisting of ubiquitin fused N-terminally to RalA) leads to RalA enrichment at the pl

154 ibrils contain an altered beta-core extended N-terminally to residue approximately 106, encompassing

155 ELR CXC chemokines CXCL1, -2, -3, -5, and -8 N-terminally to the ELR motif, thereby generating agonis

156 ons between basic (Arg/Lys) residues located N-terminally to the phosphorylated Ser/Thr residues in t

157 N-terminally truncated (96-585) GAD65 (tGAD65) autoantib

158 640R) in the context of both full-length and N-terminally truncated (DeltaNT) G1.

159 Multiple Msp2(P44) and N-terminally truncated 25- to 27-kDa isoforms having var

160 As a consequence, N-terminally truncated Abeta will accelerate fiber forma

161 N-terminally truncated Abeta(11-40) and Abeta(11-42) mak

162 Naturally occurring N-terminally truncated Abeta(11-40/42) is found in the c

163 al fragments and secreting intact as well as N-terminally truncated Abeta.

164 Intact, native alpha-defensins, N-terminally truncated alpha-defensins, and alpha-defens

165 Here we report an N-terminally truncated alternative splice variant of Chk

166 Thus, we compared the accumulation of N-terminally truncated amyloid-beta and full-length amyl

167 fraction, cerebrospinal fluid largely lacked N-terminally truncated amyloid-beta species and exhibite

168 across disease stages and brain areas, while N-terminally truncated amyloid-beta40 and full-length am

169 N-terminally truncated amyloid-beta42 accumulation showe

170 by APOE) were more strongly correlated with N-terminally truncated amyloid-beta42 accumulation than

171 Cortical N-terminally truncated amyloid-beta42 accumulation was i

172 We observed that N-terminally truncated amyloid-beta42 and full-length am

173 clinical records showed that accumulation of N-terminally truncated amyloid-beta42 in cortical areas

174 Collectively, N-terminally truncated amyloid-beta42 species have spati

175 ss spectrometry analysis showed that several N-terminally truncated amyloid-beta42 species, represent

176 Moreover, N-terminally truncated amyloid-beta42 were more likely t

177 The resultant eIF4A protein is N-terminally truncated and acts as eIF4A inhibitor.

178 Although both N-terminally truncated and full-length MCL1 contain sequ

179 N-terminally truncated and pyroglutamated Abeta peptides

180 peptides, including full-length p19(Arf) and N-terminally truncated and unstable p15(smArf) ("small m

181 0-kDa protein and a constitutively expressed N-terminally truncated approximately 110-kDa protein.

182 hosphatidyl inositol 3,4,5-trisphosphate and N-terminally truncated Arf6-GTP reveals a large conforma

183 Coexpression of AtPRK2a with an N-terminally truncated AtRopGEF12 did not induce isotrop

184 um-mediated transient expression analysis of N-terminally truncated AvrRPS4 mutants revealed that the

185 uding alternative splicing that produces the N-terminally truncated BAD(S).

186 Lef-1 FL) while decreasing expression of the N-terminally truncated beta-catenin-independent isoform.

187 Most of the proteins were N-terminally truncated by endoproteases or exopeptidases

188 mplex between the full-length protein and an N-terminally truncated C-terminal cell wall binding doma

189 FE65, p97FE65) can be converted to a 65-kDa N-terminally truncated C-terminal fragment (p65FE65) via

190 N-terminally truncated CAF-1 p150 was deficient in proli

191 Autoactivation of N-terminally truncated cationic trypsinogen is stimulate

192 autoinhibitory region is deleted, to give an N-terminally truncated CAX (sCAX), or altered through sp

193 In addition, N-terminally truncated CCL15/MIP-1delta and CCL23/CKbeta

194 We solved the 2.0 A crystal structure of N-terminally truncated CofB, revealing a pilin-like prot

195 cause of weakened microtubule binding, as an N-terminally truncated complex with similar binding affi

196 In the present studies, C-terminally and N-terminally truncated constructs were characterized in

197 ant betaA3- and betaB1-crystallins and their N-terminally truncated counterparts (betaA3DeltaN30 and

198 In addition, N-terminally truncated cytoplasmic isoforms of LANA, res

199 ed via the cag pathogenicity island, induces N-terminally truncated Delta133p53 and Delta160p53 isofo

200 ing functions: the full-length TAp73 and the N-terminally truncated DeltaNp73.

201 s of proteins: the full-length TAp73 and the N-terminally truncated DeltaNp73.

202 elastase (ELANE) result in the production of N-terminally truncated elastase, which mislocates to the

203 sion results in expression of full-length or N-terminally truncated ERG protein in prostate epithelia

204 t when expressed in stable S2 cell lines, an N-terminally truncated ESC (FLAG-ESC61-425), like full-l

205 However, incorporation of this N-terminally truncated ESC into E(Z) complexes prevents

206 kinase activity, c-Src is associated with an N-terminally truncated estrogen receptor alpha variant (

207 N-terminally truncated EYFP-CENH3(C) is deposited to and

208 In contrast, the N-terminally truncated form of Abeta, known as "p3," for

209 ne that encodes ICP22, produces an in-frame, N-terminally truncated form of ICP22, known as US1.5.

210 cultures, inhibition of IKK activity with an N-terminally truncated form of IKKgamma blocks mutant Ht

211 The N-terminally truncated form of MCL1 was expressed to var

212 tion-dependent manner with MrpC or MrpC2, an N-terminally truncated form of MrpC.

213 nsmissible disease in mice overexpressing an N-terminally truncated form of PrP(C).

214 Tg(PrPDelta32-134) mice, which express an N-terminally truncated form of PrP, spontaneously develo

215 LPS also induces expression of Ron and an N-terminally truncated form of Ron, Sf-Ron, in primary m

216 We have previously reported an N-terminally truncated form of tau in human brain that i

217 We have expressed and purified an N-terminally truncated form of the 580-residue UL25 prot

218 n in the colons of mutant mice expressing an N-terminally truncated form of ZBP-89 was not observed a

219 f p63 expressed in SCC is DeltaNp63alpha, an N-terminally truncated form which functions as a key SCC

220 nd p63, express multiple splice variants and N-terminally truncated forms initiated from an alternati

221 the six most abundant known Crps, as well as N-terminally truncated forms of each, and that the pepti

222 mechanism of translocation, we characterized N-terminally truncated forms of the PA63-binding domain

223 In the absence of N-terminally truncated forms, blocking Nix-mediated mito

224 levant signals in GADA RBAs and suggest that N-terminally truncated GAD labels will enable more speci

225 ull-length GAD, suggesting that assays using N-terminally truncated GAD should be used to select part

226 ily study were reassayed with full-length or N-terminally truncated GAD using the National Institute

227 This finding prompted development of an N-terminally truncated GAD65 radiolabel, (35)S-GAD65(96-

228 to assay type and indicated that the use of N-terminally truncated GAD65 radiolabels in GADA radiobi

229 In the same assays, the N-terminally truncated GAIP/RGS19 did not distinguish OR

230 t both full-length/glycosylated beta1ARs and N-terminally truncated glycosylation-defective beta1ARs

231 all angle x-ray scattering experiments on an N-terminally truncated Gt CsoR (Delta2-10) reveal that t

232 The complex comprises one subunit each of an N-terminally truncated Ino80, actin, Arp4, Arp5, Arp8, I

233 s of p73 and reduced levels of the oncogenic N-terminally truncated isoform DeltaNp73 in Aldefluor(+)

234 Moreover, the accumulation of StpX and an N-terminally truncated isoform is differentially coordin

235 ly, we along with others have found that the N-terminally truncated isoform of p73, DeltaNp73, has po

236 DeltaNp73alpha is an N-terminally truncated isoform of p73.

237 ly, inhibition of hair follicle formation by N-terminally truncated Lef1 results in upregulation of C

238 A full-length pre-protein (66 kDa) and an N-terminally truncated mature form (55 kDa) have been de

239 response to UV light appears to be normal in N-terminally truncated mcm10 mutants, we propose that Mc

240 As a consequence, N-terminally truncated Mdm2 binds p53 and promotes its s

241 id not seem to affect the association of the N-terminally truncated minireceptors with WT-M, except t

242 We report here that human p75(MDM2) is an N-terminally truncated mixture of protein isoforms produ

243 ed into transgenic (Tg) 9949 mice expressing N-terminally truncated MoPrP(Delta23-88) and WT FVB mice

244 ere involved in this regulation, a series of N-terminally truncated mutants were constructed which co

245 Pan-neuronal expression of full-length or N-terminally truncated mutHtt recapitulates sleep phenot

246 mutant/mutant (NBS1m/m) mice that express an N-terminally truncated NBS1 at lower levels.

247 An N-terminally truncated NKCC1 (nttNKCC1), in which the fi

248 The N-terminally truncated NS1 encoded by the H1N1 PR8 strai

249 -related protein (PTHrP) receptor (PTHR) are N-terminally truncated or N-terminally modified analogs

250 expression of full-length P protein (P1) and N-terminally truncated P proteins (tPs), designated P2,

251 d C-terminal transmembrane domain, and is an N-terminally truncated paralog of two other EFC proteins

252 Here we report the crystal structure of an N-terminally truncated PCV2 virus-like particle at 2.3-A

253 nd telcagepant (K(D) < 0.02 muM), as well as N-terminally truncated peptides and peptide analogues (1

254 The four N-terminally truncated peptides showed increased oligome

255 ion to Abeta n-40 and Abeta n-42, as well as N-terminally truncated peptides, suggesting anomalous pr

256 garnered no information on the import of an N-terminally truncated PEX5 (PEX5C) receptor construct o

257 ocesses it to a unique, triple-sulfated, and N-terminally truncated product distinct from intestinal

258 in translation re-start and production of a N-terminally truncated protein (p.M1_E165del) that is un

259 eurons (MN-1), and is predicted to encode an N-terminally truncated protein isoform.

260 er bisindoylmaleimide I and was absent in an N-terminally truncated protein that lacks the first 21 r

261 g full-length PrP (residues 23-231, FL_PrP), N-terminally truncated PrP (residues 90-231, T_PrP), and

262 In contrast, the appearance of the N-terminally truncated PrP species coincides with the pr

263 ed, full-length PrP species and the aberrant N-terminally truncated PrP species may be important in t

264 glycosylated, full-length PrP species and an N-terminally truncated PrP species that are not detectab

265 The levels of the N-terminally truncated PrP species vary depending on PrP

266 In contrast, coexpression of N-terminally truncated PrP(Delta23-88) did not affect di

267 N-terminally truncated PrP(Sc), denoted PrP 27-30, retai

268 able to the presence of miniscule amounts of N-terminally truncated PrPs, where a PrP encompassing re

269 The N-terminally truncated PTBP3 isoforms lack nuclear local

270 deposition both in vitro and in vivo Because N-terminally truncated pyroglutamate (pE)-modified Abeta

271 Here, we show that M. genitalium expresses N-terminally truncated RecA isoforms via alternative tra

272 ost factor required for the activation of an N-terminally truncated recombinant TBSV RdRp.

273 inant mouse PrP [denoted recPrP(23-230)] and N-terminally truncated recPrP(89-230), as well as their

274 d in the same reading frame and MCM3AP is an N-terminally truncated region of GANP.

275 ately 50% of LANA1 is naturally generated as N-terminally truncated shoulder proteins that are detect

276 S and FTLD-U, aggregated, ubiquitinated, and N-terminally truncated TDP-43 can be isolated from brain

277 hereas the more distal disulfide bond of the N-terminally truncated Topo70-clamp(499) did not.

278 N-terminally truncated TPC2 (TPC2delN), which is targete

279 ceptor potential melastatin-8 (TRPM8) and an N-terminally truncated TRPM8 variant (TRPM8-Delta801) ar

280 lobulin (hbeta2m) can co-polymerize with its N-terminally truncated variant (DeltaN6) in vitro to for

281 ength GAIP/RGS19 was more effective than the N-terminally truncated variant and was more selective in

282 sphate dehydrogenase (G6PDH) by ClpB and its N-terminally truncated variant ClpBDeltaN in the presenc

283 the 2.0 A resolution crystal structure of an N-terminally truncated variant of EpsH, a minor pseudopi

284 ometry, and this complex is not formed by an N-terminally truncated variant of gp42.

285 pH 7.7, but not at pH 5.5 or 2.5, while both N-terminally truncated variants can form fibrils at thes

286 Either the full-length CRD-BP or the N-terminally truncated version can rescue the clonogenic

287 We found that an N-terminally truncated version of FOG1 is produced from

288 Similarly, both an N-terminally truncated version of Gag that is missing th

289 his study, we examined a naturally occurring N-terminally truncated version of UL12 called UL12.5.

290 ated fibres consist almost completely of the N-terminally truncated version, suggesting that the prot

291 The great majority of AD plaque consists of N-terminally truncated versions of Abeta(1-40/1-42), wit

292 ng the Galpha portion, but not Gsalpha or an N-terminally truncated XLalphas mutant unable to interac

293 Notably, N-terminally truncated YscF induced significantly higher

294 cases and often lead to the expression of an N-terminally truncated, 30 kDa isoform, C/EBPalphap30, f

295 ography to delineate molecular models of the N-terminally truncated, disease-causing isoform (PrP(Sc)

296 A major fraction of secreted FGE is N-terminally truncated, lacking residues 34-72.

297 he reproductive and gestational tissues were N-terminally truncated, similar to urine PrP.

298 We fused N-terminally truncated, stabilised beta-catenin to the l

299 nd 136-158 grafts was mutated, scrambled, or N-terminally truncated.

300 ned with cerulean fluorescent protein tagged N-terminally with a GAP43 motif and C-terminally with a