ライフサイエンスコーパス: NA

1 NA displays sialidase activity by cleaving off the termi

2 NA is applicable to many fields, including computational

3 NA is important as it releases progeny viruses from the

4 NA mutations previously known to confer oseltamivir resi

5 d or highly reduced inhibition by at least 1 NA inhibitor; half of them caused reduced inhibition or

6 s critical for the NA activity of pH1N1low-1 NA, although 19M or 248D in conjunction with 66Y was req

7 We identified 16 NA substitutions conferring NAI resistance in the tested

8 Conversely, when segment 6 (NA) or segment 8 (NS) carried modified packaging signals

9 Peanut allergy can be established in a NA hosts with B220(+) cells from PA donors and CD4(+) ce

10 ed from improved working memory with the a2A-NA agonist Guanfacine.

11 assays may be useful for estimating abiotic NA rates of contaminants in groundwater.

12 For example, although natural Abs (NA) and complement are key components of the innate immu

13 exposed to N-acetoxy-2-acetylaminofluorene (NA-AAF), which generates bulky DNA adducts that block RN

14 uinolone antibiotics such as nalidixic acid (NA) and flumequine (FLU), but also salicylic acid (SA),

15 that whole OSPW containing naphthenic acid (NA) concentrations ranging from 12 to 18 mg/L, significa

16 oatomic (sulfur-containing) naphthenic acid (NA) species from unprocessed and ozone-treated oil sands

17 Here we report that nicotinic acid (NA), an essential vitamin, inhibits glioma cell invasion

18 We have analysed nucleic acid (NA) binding and processing by full-length hUPF1.

19 s (PN), polysaccharides (PS), nucleic acids (NA) and humic-like substances (HS) in the STAD system wi

20 Naphthenic acids (NAs) and thousands of bitumen-derived organics were char

21 64.0% and 78.4% removal of naphthenic acids (NAs) at the dose of 200 mg/L and 400 mg/L Fe(VI) respect

22 Naphthenic acids (NAs) removals in the UV-NTA-Fenton process (98.4%, 86.0%

23 ses involve the stretching of nucleic acids (NAs).

24 symptoms, smoking urge, and negative affect (NA)) followed by an analog smoking reinstatement task fo

25 .0% at 12 and 24 months, respectively, after NA discontinuation without being affected by the duratio

26 t 12, 24, and 36 months, respectively, after NA discontinuation, being relatively higher in initially

27 Network alignment (NA) aims to find a node mapping that conserves similar r

28 step may be modeled as a network alignment (NA) problem.

29 hibition or highly reduced inhibition by all NA inhibitors.

30 Although NA is immunologically subdominant to HA, and clinical st

31 emissions from dairy cows in North America (NA), Europe (EU), and Australia and New Zealand (AUNZ) a

32 st Asia (EA), Europe (EU) and North America (NA).

33 ime after cessation of nucleos(t)ide analog (NA) treatment in patients with chronic hepatitis B (CHB)

34 ection (CHB) with the nucleos(t)ide analogs (NAs) entecavir or tenofovir.

35 with off-treatment nucleos(t)ide analogues (NA) in chronic hepatitis B patients (CHB) is unclear.

36 ical treatment with nucleos(t)ide analogues (NA) may suppress HBV replication with little or no impac

37 s, and 33% received nucleos(t)ide analogues (NAs) only.

38 atitis B (CHB) with nucleos(t)ide analogues (NAs) suppresses hepatitis B virus (HBV) DNA production b

39 Changes in hemagglutinin (HA) binding and NA specificity in reassortant viruses may be related to

40 f CYP2A13 and CYP2F1 in NA bioactivation and NA-induced respiratory tract toxicity in mouse models.

41 se in AF and OIS compared to BRAO, CRAO, and NA-AION (p<0.0001).

42 igens, particularly antibodies to the HA and NA glycoproteins.

43 te both proteins being raft resident, HA and NA occupy distinct but adjacent membrane domains.

44 This is complicated by HA and NA residing in lipid raft-like domains, whereas M2, alth

45 HA and NA, while raft associated, reside in distinct domains, r

46 Then PN, PS and NA gradually decreased, while HS showed only minor decea

47 is known that beta-adrenergic receptors and NA can boost LTP maintenance by regulating translation.

48 ficantly slower rates than native virus, and NA-lacking pseudoparticles exhibiting the slowest fusion

49 ed NAs with one additional oxygen atom), and NAs + 2O (oxidized NAs with two additional oxygen atoms)

50 0 mg/L and 400 mg/L Fe(VI) respectively, and NAs with high carbon number and ring number were removed

51 m nucleus laminaris (NL), nucleus angularis (NA), and regio intermedius (RI) in the brainstem, innerv

52 roadly neutralizing anti-neuraminidase (anti-NA) mAb also required FcgammaRs to provide protection in

53 otection in vivo, but a strain-specific anti-NA mAb did not.

54 trate the concept, a 0.5 numerical aperture (NA) confocal fluorescence microscope is prototyped with

55 on imaging requires high numerical aperture (NA) lenses, which are bulky and expensive.

56 ing very close to a high numerical-aperture (NA) benchtop microscope that is corrected for color dist

57 port resistance testing in cases of apparent NA therapy failure.

58 s can be optimized with any state-of-the-art NA method and not just MAGNA++.

59 In addition, at NA concentrations of 10 mg/L, whole OSPW but not the OSP

60 ogically negative for HBeAg and viral DNA at NA cessation.

61 demonstrate that exposure to whole OSPW (at NA doses ranging from 10 to 20 mg/L), but not the OSPW-O

62 ival was 16 months (95% CI 13-not available [NA]).

63 ir) as determined using a fluorescence-based NA inhibition assay.

64 us erythematosus and a Syk inhibitor blocked NA-TLR localization with FcgammaRIIIa.

65 Blocking NA abolished the effects of EMs on the vividness of emot

66 We predicted that blocking NA would abolish the memory degrading effects of EMs.

67 r therapeutic efficacy can be compromised by NA changes that emerge naturally and/or following antivi

68 c) and N-glycolylneuraminic acid (Neu5Gc) by NA in H9 virus replication was observed by reverse genet

69 mbrane that solves this problem by capturing NAs with high sensitivity in a short time period, follow

70 We show that in CD4(+) T cells, NA-TLRs, TLR3, TLR8, and TLR9 are upregulated by Fcgamma

71 ocess (98.4%, 86.0%, and 81.0% for classical NAs, NAs + O (oxidized NAs with one additional oxygen at

72 under experimentally short winter conditions NA species required 84% more spring warming for bud brea

73 l, aromatic, oxidized, and sulfur-containing NA compounds were eluted into individual SPE fractions.

74 matitis (AD), and nonatopic healthy control (NA) subjects were enrolled.

75 hosphorylation on Y397 of FAK promotes dense NA formation but is dispensable for transient NA stabili

76 We design NA-electrode sensing system based on C-, N-doped NiO bro

77 Cohort Collaboration on Research and Design (NA-ACCORD).

78 these needs, but they are not able to detect NAs present in zeptomolar concentrations in short time f

79 cal relapses in CHB patients who discontinue NA treatment.

80 This proof-of-concept dynamic NA method is an extension of a state-of-the-art static N

81 purpose, we introduce the first ever dynamic NA method, DynaMAGNA ++.

82 We confirm our hypothesis that dynamic NA is superior to static NA, on synthetic and real-world

83 2K (N2 numbering), were introduced into each NA gene for comparison.

84 Our results demonstrate that each NA subtype possesses unique NAI resistance markers, and

85 Elevated NA concentrations and bitumen-derived organics were dete

86 or pandemic (H1N1) influenza virus, elicited NA-specific antibody and T cell responses, which conferr

87 hat substrate binding via this site enhances NA catalytic activity.

88 Existing NA methods can only align static networks.

89 s 5 recombinant vaccine candidate expressing NA (PIV5-NA) from a pandemic influenza (pdmH1N1) virus o

90 These findings indicate that PIV5 expressing NA may be effective as a broadly protective vaccine agai

91 5), a promising live viral vector expressing NA from avian (H5N1) or pandemic (H1N1) influenza virus,

92 tion of the three-coordinate imido ((Ar)L)Fe(NAd) (5) with chlorotriphenylmethane afforded ((Ar)L)FeC

93 (S = 5/2), three-coordinate imidos ((Ar)L)Fe(NAd) and ((Ar)L)Fe(NMes), respectively, as determined by

94 tive with a variety of substrates: ((Ar)L)Fe(NAd) reacts with azide yielding a ferrous tetrazido ((Ar

95 lorotriphenylmethane afforded ((Ar)L)FeCl((*)NAd) (6) with concomitant expulsion of Ph3C(C6H5)CPh2.

96 indicating that the mechanism of action for NA in cell migration is evolutionarily conserved.

97 rotein and evaluate potential advantages for NA standardization in influenza vaccines has emerged.

98 ong the uncertainties in risk assessment for NA is whether human lung CYP2A13 and CYP2F1 can mediate

99 ement in binding capability of magnetite for NA is still observed in the presence of environmentally

100 ase showed similar adsorption properties for NA or FLU.

101 ty of the NA tetramer and, subsequently, for NA enzymatic activity.

102 ty of the NA tetramer and, subsequently, for NA enzymatic activity.

103 thout the requirement of pre-methylation for NAs.

104 surements (g per lactating cow per day) from NA, EU, and AUNZ, respectively.

105 s and software provide guidelines for future NA method development and evaluation.

106 ing sequences of the influenza glycoproteins NA and HA also function as translational regulatory elem

107 nations and general preferences for the H3N2 NA, pH1N1 M, and H3N2 PB2 except when paired with the pH

108 Some proteins, like hemagglutinin (HA), NA, and M2, are integral membrane proteins.

109 Individually, HA, NA, M1, M2, and NP were shown to self-associate in or on

110 te with six gene segments (PB2, PB1, PA, HA, NA, and NS) sharing >99% sequence identity with those of

111 ery broad, with recognition of the viral HA, NA, M1, NS1, and NP proteins, and that total reactivity

112 Pseudoparticles harboring mismatched HA-NA pairings fuse at significantly slower rates than nati

113 High NA concentrations and bitumen-derived organics were also

114 e ability to tightly focus it through a high NA lens allowed precise, rapid targeting of subsets of c

115 January 2009 to December 2011, we identified NA-naive patients who were at least 20 years of age diag

116 e paired mutation of residues 356 and 431 in NA was necessary for the viral replication in duck intes

117 in OIS, 22% in BRAO, 21% in CRAO, and 6% in NA-AION patients.

118 e widespread assumption that such changes in NA are obtained only after acquisition of functional cha

119 he in vivo function of CYP2A13 and CYP2F1 in NA bioactivation and NA-induced respiratory tract toxici

120 iol was associated with greater decreases in NA.

121 iol was associated with greater decreases in NA.

122 echanistically separable functions of FAK in NA are required for cells to distinguish distinct proper

123 ce 1900, STV has been consistently higher in NA than in EU and EA, and under experimentally short win

124 predictor variables, were ranked highest in NA (RMSPE = 13.1% and CCC = 0.78).

125 dy does not result in the transfer of PNA in NA recipients, demonstrating that anti-CD20 antibody tre

126 s were associated with greater reductions in NA.

127 ough effects on focal adhesions, its role in NA formation and lamellipodial dynamics is unclear.

128 d mice, where they play significant roles in NA-induced respiratory tract toxicity.

129 New vaccination strategies incorporating NA, including PIV5-NA, could improve seasonal influenza

130 a valuable method for extracting individual NA species that are of great interest for environmental

131 During infection, NA is important for the release of influenza virions fro

132 taining a clade IV-A HA gene, a 2002-lineage NA gene, an M-pdm09 gene, and remaining gene segments of

133 e molecular determinants associated with low NA activity as potential markers of aerosol transmission

134 Here we report an updated webserver for mCSM-NA, the only scalable method we are aware of capable of

135 er human lung CYP2A13 and CYP2F1 can mediate NA's respiratory tract toxicity.

136 Mervish NA, Pajak A, Teitelbaum SL, Pinney SM, Windham GC, Kushi

137 Rates of microsomal NA bioactivation and the effects of an anti-CYP2A antibo

138 FcgammaRIIIa-pSyk cosignaling in modulating NA-TLR responses in human CD4(+) T cells by affecting th

139 ths) versus 9.3 months (95% CI: 6.21 months, NA; p < 0.016); odds ratio: 0.11 (95% CI: 0.03 to 0.37;

140 stance, we measured the activities of mutant NA proteins transiently expressed in 293 cells after pH

141 Therefore, 66Y in the stalk domain of N1 NA was critical for the stability of the NA tetramer and

142 Vaccination with PIV5-N1 NA provided cross-protection against challenge with a he

143 domain, where 66Y was highly conserved in N1 NAs.

144 resistance in AIVs of the N4, N5, N6, and N8 NA subtypes using gene-fragmented random mutagenesis.

145 NAI resistance in AIVs of N4, N5, N6, and N8 NA subtypes, random mutations within the target gene wer

146 N9 NA has previously been shown to have receptor binding pr

147 substitutions in AIVs of the N3, N7, and N9 NA subtypes.

148 We also show that the N9 NA can also contribute to receptor binding due to unusua

149 This study investigated the N9 NA from a zoonotic H7N9 virus strain in order to determi

150 We demonstrate that this N9 NA has an active Hb site which binds to sialic acid, whi

151 he potential carcinogenicity of naphthalene (NA), a ubiquitous environmental pollutant, in human resp

152 (98.4%, 86.0%, and 81.0% for classical NAs, NAs + O (oxidized NAs with one additional oxygen atom),

153 Neuraminidase (NA) activity facilitates the release of viruses from cel

154 Neuraminidase (NA) inhibitors are the recommended antiviral medications

155 Neuraminidase (NA) is a sialidase expressed on the surface of influenza

156 Neuraminidase (NA) is a sialidase that is one of the major surface glyc

157 Although neuraminidase (NA) inhibitors (NAIs) are the only class of antiviral dr

158 ptor binding domain (RBD) and neuraminidase (NA) catalytic site were identified.

159 RG) viruses expressing HA and neuraminidase (NA) from 3 different H7 viruses [A/Shanghai/2/2013(H7N9)

160 of the hemagglutinin (HA) and neuraminidase (NA) genes of this seal influenza A(H10N7) virus revealed

161 oteins hemagglutinin (HA) and neuraminidase (NA) with the cell surface receptor sialic acid.

162 or IAV surface glycoproteins, neuraminidase (NA) and M2 ion channel, is essential for the replication

163 ized with hemagglutinin (HA), neuraminidase (NA) and the extracellular domain of matrix protein 2 (M2

164 combinant hemagglutinin (HA), neuraminidase (NA), and nucleoprotein (NP) proteins.

165 reness of the contribution of neuraminidase (NA) to influenza virus vaccine efficacy.

166 nterest in the development of neuraminidase (NA)-specific methods to characterize the glycoprotein an

167 rporated increased numbers of neuraminidase (NA).

168 n (HA) glycoprotein, with the neuraminidase (NA) glycoprotein being responsible for cleaving the rece

169 The neuraminidase (NA) inhibitor, oseltamivir, is a widely used anti-influe

170 The neuraminidase (NA) surface glycoprotein, while diverse, has a conserved

171 ) (H5N1), with its unmodified neuraminidase (NA) gene; this virus was designated Egy/09 ca The second

172 s may be attributed to a weak neuraminidase (NA) cleavage of carbon-6-linked sialic acid (Sia) rather

173 segments (hemagglutinin [HA], neuraminidase [NA], and matrix [M]) of seasonal influenza A and B virus

174 ow that the corresponding N9 neuraminidases (NAs) display equal enzymatic activities on a soluble mon

175 rteritic anterior ischemic optic neuropathy (NA-AION) and amaurosis fugax (AF).

176 ental health (MH) disorders or nonadherence (NA) may be barriers to completing the work-up (WU) and/o

177 Noradrenaline (NA) strengthens memory (re)consolidation.

178 mine neurotransmitter such as noradrenaline (NA) in living cells with simple, sensitive and selective

179 he Egypt H5N1 viruses, and contained a novel NA subtype for humans.

180 ance were mainly categorized as either novel NA subtype specific (G/N147V/I, A246V, and I427L) or pre

181 Position 223 of NA is located adjacent to a hydrophobic portion of oselt

182 CRAO and 53% of BRAO compared to only 3% of NA-AION patients (p<0.0001).

183 in 17% of OIS, 11% of AF, 7% of CRAO, 6% of NA-AION, and 3% of BRAO patients.

184 II) = 0.40) led to similar sorbed amounts of NA, FLU, SA, silicates or HA as compared to the stoichio

185 the plasma membrane; however, in the case of NA and M2, clustering depends upon the expression system

186 ass spectrometry (MS/MS) characterization of NA compounds due to the removal of matrix and a simplifi

187 ter surfaces for ultrasensitive detection of NA in living cells such as PC12.

188 long-term stability during the detection of NA may open their practical, in-vitro application for ex

189 V without the stalk and catalytic domains of NA as a live attenuated vaccine was shown to confer a st

190 a valuable tool for assessing the effect of NA changes on drug susceptibility of emerging influenza

191 y, enhanced kinetics for electrooxidation of NA, and fast electron-transfer between electrode-electro

192 The free energy of NA folding therefore depends on the interactions of this

193 The extent of NA respiratory toxicity was compared among wild-type, Cy

194 3/2F1-humanized mice; however, the extent of NA-induced lung injury (shown as volume fraction of dama

195 Glycosylation of NA in the stalk region affects its structure, activity,

196 Similarly, patients with a history of NA had a 21% lower hazard of completing the WU (hazard r

197 In this study, we address the involvement of NA and the complement system in the activation of innate

198 Subcellular location of NA-TLRs is a key determinant in discriminating self vers

199 These data suggest that movement of NA and NS segments between the human H3N2 and H1N1 linea

200 Here, we report profiles of NA substitutions that confer NAI resistance in AIVs of t

201 enza A virus; however, the key properties of NA for viral infection in duck are not well understood.

202 in, but also on the functional properties of NA.

203 Direct LC-MS/MS quantification of NA-released sialic acid provides precise measurement of

204 g the ER-targeting sequence coding region of NA into different 5' UTRs confirmed that NS1 can promote

205 owed evidence of monitoring and screening of NA released from PC12 cells under K(+) ion-extracellular

206 all results indicated that the separation of NA species using Ag-ion SPE is a valuable method for ext

207 hat are found in the 2nd SIA-binding site of NA proteins of avian-derived IAVs that became human pand

208 Studies of NA stability and molecular modeling revealed that 66Y li

209 n the OM, at 2 or 20 hr after termination of NA exposure, in humanized mice.

210 The unique features of CNNB in terms of NA-selectivity among multi-competitive components, long-

211 nding, RNA folding and the polymer nature of NAs.

212 a force induces changes in the structure of NAs at the atomic level is a challenge.

213 VR > 24 months offers higher chances of off-NA VR in patients with HBeAg-negative chronic hepatitis

214 of real-world selection pressures acting on NA.

215 ceptor-binding properties have been based on NA was developed for the first time.

216 systematically reviewed the existing data on NA discontinuation in this setting and tried to identify

217 n interaction between Patch and estradiol on NA.

218 ionship between a history of MH disorders or NA and the likelihood of completing the WU or undergoing

219 ation between the history of MH disorders or NA and the time from referral to WU completion or KT wer

220 gs suggest that a history of MH disorders or NA is a potential barrier to KT.

221 A history of MH disorders or NA was present in 24% and 18%, respectively.

222 luster, but the association of M1 with HA or NA is dependent upon the means of expression.

223 toward H7N9 NP, as compared with H7N9 HA or NA proteins, and correlated strongly with ADCC-Abs titer

224 ADCC-Abs titers directed against H7N9 HA or NA proteins.

225 oparticles was higher than in mismatching or NA-lacking pseudoparticles.

226 pean CHB patients have been exposed to other NAs, which are associated with therapy failure and resis

227 itional oxygen atom), and NAs + 2O (oxidized NAs with two additional oxygen atoms), respectively) und

228 d 81.0% for classical NAs, NAs + O (oxidized NAs with one additional oxygen atom), and NAs + 2O (oxid

229 ssed five H7N8-like gene segments (PB2, PB1, NA, MP, and NS; >98% sequence identity).

230 3 virus reassorted efficiently with the PB2, NA, and M segments from the 2009 pandemic H1N1 (PH1N1) v

231 ) reassortant viruses revealed that the PB2, NA, or M segments from PH1N1 largely do not attenuate th

232 from PA donors and CD4(+) cells from peanut-NA donors.

233 strategies incorporating NA, including PIV5-NA, could improve seasonal influenza virus vaccine effic

234 binant vaccine candidate expressing NA (PIV5-NA) from a pandemic influenza (pdmH1N1) virus or highly

235 The iron(IV) imide complexes, (Me2IPr)-R2Fe=NAd (R = (neo)Pe (3a), 1-nor (3b)) undergo migratory ins

236 Moreover, separated NA species facilitated the tandem mass spectrometry (MS/

237 y 6nM and reproducibility of broccoli-shaped NA-electrodes.

238 Similarly, NA transiently inhibits neural crest migration in Xenopu

239 Disease Control and Prevention standardized NA inhibition (NI) assay with oseltamivir, zanamivir, pe

240 is an extension of a state-of-the-art static NA method, MAGNA++.

241 thesis that dynamic NA is superior to static NA, on synthetic and real-world networks, in computation

242 lternatively, hUPF1 binds to single-stranded NAs (ssNA) with apparent affinity increasing with substr

243 In summary, NA- and M2e-based immunity can protect against challenge

244 nano-tubular arrangements enabled to tailor NA biosensor design.

245 ortion of patients who discontinue long-term NA therapy; on-therapy VR > 24 months offers higher chan

246 a stronger decrease in the HBV RNA load than NA monotherapy, and this decline was more pronounced in

247 The results confirm that NA algorithms may be applied in cases of atlas-free parc

248 We demonstrate that NA, although binding to PapMV, are not involved in its r

249 dness of emotional memories, indicating that NA is crucial for EMDR effectiveness and possibly streng

250 We further show that NA injection blocks the infiltration of tumor cells into

251 These results suggest that NA treatment may be developed into a potential therapy f

252 The NA assay revealed that the activity of Dk78/Eng62N2 almo

253 acid to allow virus internalization and the NA is a sialidase responsible for cleaving sialic acid t

254 152K, a naturally occurring variation at the NA catalytic residue of A(H7N9) viruses, conferred reduc

255 Restoration of 66Y was critical for the NA activity of pH1N1low-1 NA, although 19M or 248D in co

256 gions of the Ov proper mostly arise from the NA-recipient zone of MLd.

257 an arterial blood pressure was normal in the NA group; severe hypotension and high mortality were obs

258 ruses with amino acids (38KQ) deleted in the NA stalk, and changing the amino acid at position 431 fr

259 acid substitutions were introduced into the NA of A/Shanghai/2/2013(H7N9).

260 excess: the number of ions present near the NA in excess of the bulk concentration.

261 aging signals on the HA segment, but not the NA or NS segments, restricted IAV reassortment.

262 N1 NA was critical for the stability of the NA tetramer and, subsequently, for NA enzymatic activity

263 d that was critical for the stability of the NA tetramer and, subsequently, for NA enzymatic activity

264 th (lambdaa = lambdaprobe/2n) and not on the NA of the optics allowing sub-optical wavelength acousti

265 Overall, the NA processing activities of hUPF1 are consistent with it

266 ling revealed that 66Y likely stabilized the NA homotetramer.

267 In vitro studies indicated that the NA bioactivation activities in OM and lung of the CYP2A1

268 ates for purified protein and virus that the NA of the zoonotic H7N9 viruses has a binding capacity v

269 Previous studies showed that the NA proteins of the N9 subtype can bind sialic acid via a

270 complexation modeling, it was shown that the NA-magnetite complexation constant does not vary with Fe

271 ified 37 amino acid substitutions within the NA gene, 16 of which (4 in N4, 4 in N5, 4 in N6, and 4 i

272 Therefore, NA might either play no significant role or serve to str

273 Continued use of these NAs needs to be reconsidered at a pan-European level.

274 o changes in the sugar pucker angle of these NAs.

275 are recognized by nucleic acid-sensing TLRs (NA-TLRs).

276 ntibody transfer indicate that antibodies to NA have an important role in protection.

277 This can be attributed to NA's ability to facilitate the ubiquitination and degrad

278 ntly higher in OIS, AF, and CRAO compared to NA-AION (p=0.002, p=0.003, and p=0.0003, respectively).

279 osphorylated in non-cycling cells exposed to NA-AAF in a manner largely dependent on ATR kinase activ

280 ction, which promotes Arp2/3 localization to NA and reduces FAK activity.

281 enzymatic activity but confer resistance to NA inhibitors have been characterized; however, the impo

282 erely abrogated ATR signaling in response to NA-AAF and camptothecin.

283 humanized mice showed greater sensitivity to NA than Cyp2abfgs-null mice, with greater depletion of n

284 Both CYP2A13 and CYP2F1 are active toward NA in the CYP2A13/2F1-humanized mice, where they play si

285 In contrast, transient NA stabilization and advance of the cell edge requires F

286 A formation but is dispensable for transient NA stabilization and leading edge advance.

287 There exist two NA categories: local (LNA) and global (GNA).

288 charide tested contained both undersulfated (NA) domains and highly sulfated (NS) domains as well as

289 /2012 (pH1N1low-2), with almost undetectable NA enzymatic activity compared to that of the highly hom

290 HA, and clinical studies have shown variable NA responses to vaccination, in this study, we show that

291 in gut tissue from patients with EGID versus NA subjects.

292 elds, including computational biology, where NA can guide the transfer of biological knowledge from w

293 However, it is unclear whether NA can additionally engage epigenetic mechanisms to regu

294 Treatment of the U251 glioma cells with NA in vitro results in reduced invasion, which is accomp

295 study consists of a cohort of 266 eyes with NA-AION, 203 with CRAO, 127 with BRAO, 80 with OIS and 5

296 e fabricated and designed as metalenses with NA = 0.8.

297 ints less frequently than those treated with NA (P = 0.02; HR, 4.0) or untreated patients (P = 0.05;

298 Treatment of HepG2-2.2.15 cells with NAs for 9 days reduced HBV DNA levels (by 1.98 log10 cop

299 All patients received a 3-year NA treatment and 1 year off-treatment follow-up; the ini

300 nrolled CHB patients who discontinued 3 year-NA treatment.