ライフサイエンスコーパス: New World arenavirus

1 stinct from the one used by human-pathogenic New World arenaviruses.

2 ns, including LFV, Mobala virus, and clade C New World arenaviruses.

3 uence is highly conserved among both Old and New World arenaviruses.

4 ic choriomeningitis virus (LCMV) and clade C New World arenaviruses.

5 entical or similar sites utilized in several New World arenaviruses.

6 receptor usage and GP1 sequences of Old and New World arenaviruses.

7 tive against LASV, but not those specific to New World arenaviruses.

8 tically divergent from the classical Old and New World arenaviruses and also differ substantially fro

9 Our data show that these New World arenaviruses are specifically adapted to the T

10 cology and molecular and cellular biology of New World arenaviruses, as well as a discussion of the c

11 rther classified into OW (Old World) and NW (New World) arenaviruses based on their antigenicity, phy

12 All pathogenic New World arenaviruses bind to a common region of the ap

13 at the Z protein of Tacaribe virus (TACV), a New World arenavirus, buds efficiently from cells despit

14 e cycle can be specifically inhibited in the New World arenaviruses by the small-molecule compound ST

15 NV antisera against MACV.IMPORTANCE Multiple New World arenaviruses can cause severe disease in human

16 At least five New World arenaviruses cause severe human hemorrhagic fe

17 sative agent of AHF is Junin virus (JUNV); a New World arenavirus classified as a National Institute

18 sative agent of AHF is Junin virus (JUNV); a New World arenavirus classified as an NIAID/CDC category

19 Clade B of the New World arenaviruses contains both pathogenic and nonp

20 ntal approach to assess the compatibility of New World arenaviruses, endemic in rodents, with the hos

21 bundle and presents direct verification that New World arenaviruses exhibit class I viral membrane fu

22 Transmission of hemorrhagic fever New World arenaviruses from their rodent reservoirs to h

23 tivity against pseudoviruses bearing Old and New World arenavirus glycoproteins but not against virus

24 r and thus superinfection exclusion, whether New World arenaviruses have evolved such a mechanism rem

25 stroglycan as a cell-surface receptor, while New World arenaviruses hijack transferrin receptor.

26 hogenic Lassa fever virus (LFV), and clade C New World arenaviruses is alpha-dystroglycan (alpha-DG),

27 ccine that protects against a broad range of New World arenaviruses is desirable for purposes of simp

28 The situation with New World arenaviruses is less clear: previous studies d

29 The Junin virus, a member of the New World arenaviruses, is endemic to the pampas grassla

30 SVGP resembled those of the human-pathogenic New World arenavirus Junin virus (JUNV) and other envelo

31 The New World arenavirus Junin virus (JUNV) is the causative

32 The New World arenavirus Junin virus (JUNV) is the causative

33 ocytic choriomeningitis virus (LCMV) and the New World arenavirus Junin virus (JUNV) strain Candid #1

34 n-mediated endocytosis, which is used by the New World arenavirus Junin virus, and pathways used by o

35 The New World arenaviruses, Junin, Machupo, Guanarito, Sabia

36 Compared to the New World arenaviruses, Lassa and the other Old World ar

37 und that neutralizing antibodies against two New World arenaviruses, Machupo virus (MACV) and Junin v

38 lpha-DG as a major receptor, whereas, of the New World arenaviruses, only clade C viruses (i.e., Oliv

39 Infection of guinea pigs with the New World arenavirus Pichinde virus (PICV) has been used

40 aviruses LFV, Mopeia virus, and LCMV and the New World arenavirus Sabia virus bound at high affinity

41 omparison, we noted that eight Old World and New World arenaviruses share several amino acids with th

42 g of a panel of pathogenic and nonpathogenic New World arenaviruses, suggesting that GPC cleavage rep

43 This study uses the New World arenavirus Tacaribe, a neurotropic pathogen th

44 The ability of a New World arenavirus to use human TfR1 is absolutely pre

45 humans likely occurs because the pathogenic New World arenaviruses use human transferrin receptor 1

46 es activity against viruses with the Old and New World arenavirus viral glycoprotein complex but not

47 initial studies, several additional Old and New World arenaviruses were screened for entry into mous