ライフサイエンスコーパス: PND

1 PND occurs in nearly one fifth of patients with intracer

2 o the dorsal hippocampus of postnatal day 2 (PND 2) Ts65Dn pups to explore the feasibility of early p

3 rom gestational day 12 to post-natal day 20; PND 20).

4 but becomes impassable by postnatal day 30 (PND 30).

5 ded from hippocampus of pre-pubertal (~28-32 PND) and pubertal (~35-44 PND) female wild-type or alpha

6 eyes but were younger than postnatal day 35 (PND 35) exhibited modestly increased direction selectivi

7 elopment and into adulthood (PND 16-25, 35%; PND 35-80, 54%; PND 80-120, 66%; PND 175-225, 73%), prov

8 e-pubertal (~28-32 PND) and pubertal (~35-44 PND) female wild-type or alpha4-/- mice.

9 predominantly microglia at postnatal day 5 (PND 5) to predominantly oligodendrocytes by PND 30.

10 o adulthood (PND 16-25, 35%; PND 35-80, 54%; PND 80-120, 66%; PND 175-225, 73%), providing evidence t

11 16-25, 35%; PND 35-80, 54%; PND 80-120, 66%; PND 175-225, 73%), providing evidence that synaptic circ

12 ally (0, 100, 300 or 1000 microg/day; GD 9 - PND 21) to assess activity and anxiety-like behaviors.

13 Morphine administration typically abolished PND and reduced the discharge rate of most ccRTN neurons

14 ticle, we review some classic concepts about PND and recent clinical and immunological developments,

15 nt [postnatal day (PND) 28], mid-adolescent (PND 35), or adult male rats (PND 70) were surgically imp

16 ually during development and into adulthood (PND 16-25, 35%; PND 35-80, 54%; PND 80-120, 66%; PND 175

17 Even after PND 15,D-betaHB blocked morphological changes produced b

18 types prior to (PND 5 and PND 15) and after (PND 30 and PND 60) the period when pathway receptivity i

19 At later ages (PNDs 12 and 15), a clear patchy distribution of intrinsi

20 fluoride levels were determined on ED 20 and PND 11.

21 sion in the visual cortex between PND 28 and PND 49, and 3) an increased ratio of vimentin:GFAP-label

22 to (PND 5 and PND 15) and after (PND 30 and PND 60) the period when pathway receptivity is lost.

23 levels are significantly lower at PND 4 and PND 12 than in adult animals.

24 target tissue phenotypes prior to (PND 5 and PND 15) and after (PND 30 and PND 60) the period when pa

25 ed to posit common causes of early birth and PND other than the study exposure.

26 ncreases in direction selectivity in animals PND 35 or older were explained by decreases in responses

27 ore slowly than the complexes formed by anti-PND IgG.

28 Pretreatment of the anti-PND IgG with a haptenic electrophilic phosphonate compou

29 At PND 15, adding D-betaHB to the media allowed robust long

30 At PND 15, some oligodendrocytes in the subcortical white m

31 At PND 30, vimentin, collagen IV, and fibronectin were abse

32 At PND 5, microglia are found throughout gray and white mat

33 At PND 5-15, both tissues also expressed vimentin, collagen

34 At PND 55-62, the animals were tested in an interchangeable

35 At PND 62, the only remaining loss was of the dendritic mar

36 at Ucn 1-immunoreactivity (ir) was absent at PND 1, while CART-ir was already apparent in pIIIu at bi

37 nucleus and posterodorsal medial amygdala at PND 20 and 25, respectively.

38 ratio of vimentin:GFAP-labeled astrocytes at PND 49 with reduced GFAP cell body area.

39 ) mice displayed 1) evidence of blindness at PND 49, with visual deficits detected at PND 35, 2) redu

40 alpha mRNA expression in the mouse cortex at PND 25 was significantly reduced as compared to PND 1 (p

41 wed by the secondary somatosensory cortex at PND 7.

42 at PND 49, with visual deficits detected at PND 35, 2) reduced GFAP mRNA expression in the visual co

43 status and became significantly different at PND 16.

44 ERbeta mRNA expression at PND 25 was significantly increased as compared to PND 1

45 ncreased during ontogeny and was greatest at PND 20.

46 measured together is significantly higher at PND 60 in kat2-/- mice than those of wild-type mice indi

47 g preexposure impairs contextual learning at PND 23.

48 reased with age, approaching adult levels at PND 16.

49 Ucn 1 mRNA levels are significantly lower at PND 4 and PND 12 than in adult animals.

50 ic currents measured in layer 2/3 neurons at PND 8, just after these neurons ceased to migrate, revea

51 y but not completely co-localized in pIII at PND 24.

52 was absent in CART-positive cells of pIII at PND 4 and that Ucn 1 and CART are strongly but not compl

53 exposed to PPD had reduced levels of PPI at PND 56, but not PND 35, suggesting the emergence of a se

54 Starting at PND 90, behaviour was assessed at weekly intervals in th

55 ound to be not long lasting; rats trained at PND 60, after neonatally receiving the original high dos

56 ch day on PNDs 2-14 and recorded in vitro at PNDs 15-21.

57 ing circuit, which are not functional before PND 18-25.

58 mRNA expression in the visual cortex between PND 28 and PND 49, and 3) an increased ratio of vimentin

59 in sensitivity to MK-801 were found between PND 21 and 30.

60 a similar shift of the relationship between PND and end-tidal CO(2).

61 l ischemia were observed in all mice at both PND-17 and -20.

62 ion activated the ccRTN neurons normally but PND activation and the central respiratory modulation of

63 By PND 2, ARC ERalpha and Kiss1 levels were abundant, sexua

64 By PND 30, the predominant ferritin-containing cell type wi

65 ices became more intense and well defined by PND 9.

66 (PND 5) to predominantly oligodendrocytes by PND 30.

67 rrangement of connections had taken place by PND 6.

68 5; center-to-center approximately 750 pm) by PND 6.

69 th higher levels in females, but reversed by PND 4 due to declining levels in females.

70 t 2DG uptake contralateral to stimulation by PND 6, followed by the secondary somatosensory cortex at

71 which antigen-specific T cell stimulation by PND APCs triggers IFNgamma, followed by CXCL10 productio

72 PAR) paradigm, young rats at post-natal day (PND) 16 were found to exhibit a performance deficit that

73 e prepared from rat brains at postnatal day (PND) 0-2 and were cultured for up to 60 d in vitro (DIV)

74 From postnatal day (PND) 1 to 14, litters were separated from the dam, but n

75 ue taken from C57BL/6 mice on postnatal day (PND) 1, 4, 10, 18 and 25 and expression levels were dete

76 ygdala lesions made at either Postnatal Day (PND) 10 or PND40 were tested on a series of reversal tas

77 Six female C57BL/6 mice at postnatal day (PND) 10 were administered a single gavage dose of alpha-

78 By postnatal day (PND) 12, communities separated based on exposure status

79 ission electron microscopy of postnatal day (PND) 14 Rho(P23H/+) mouse retina revealed disordered sag

80 age: it is most marked before postnatal day (PND) 14.

81 restored EPSPs in slices from postnatal day (PND) 15 rats but not in slices from PND 30 or 120 rats.

82 were killed 48 hours later on postnatal day (PND) 15, 20, and 25.

83 from embryonic day (ED) 6 to postnatal day (PND) 15.

84 he somatosensory cortex, from postnatal day (PND) 16 to PND 25 spine retractions exceeded additions,

85 fference that persisted until postnatal day (PND) 19 except in the ARC.

86 throughout development, from postnatal day (PND) 21 to adult (N=174 reliable observations).

87 ) 6 until pups were weaned on postnatal day (PND) 21.

88 D) 9 to birth and from GD9 to postnatal day (PND) 21.

89 the stress of handling) from Postnatal Day (PND) 22 to PND 40 and determined the effects of daily lo

90 required by weanling rats at postnatal day (PND) 23 to demonstrate contextual fear conditioning.

91 In the present study, we fed postnatal day (PND) 24 weanling female rats an SPI diet for 30 d [short

92 using the forced-swim test on postnatal day (PND) 25 in rats either weaned on PND 21, or left with th

93 Early adolescent [postnatal day (PND) 28], mid-adolescent (PND 35), or adult male rats (P

94 cnn1b-Tg(+)) mice to SHS from postnatal day (PND) 3-21 and lung phenotypes were examined at PND22.

95 of the parental generation to postnatal day (PND) 6 of the F2 generation to a realistically proportio

96 expression starts as early as postnatal day (PND) 7 and peaks in adult.

97 the LE and developing GE from postnatal day (PND) 7 to PND 56.

98 oved from the F1 offspring on postnatal day (PND)-1 and various analyses were performed.

99 ted to 75% to 85% oxygen from postnatal day (PND)-7 to -12 and then were abruptly placed in room air.

100 clc gene neared completion by postnatal day (PND)14, and loss of GCLC protein was complete by PND21.

101 rom gestational day 8 through postnatal day (PND)16.

102 e upper lip in neonatal rats (postnatal day [PND] 1-30).

103 vehicle) twice/day for 11 consecutive days (PND 45-55).

104 ions in the visual cortex of postnatal days (PND) 1 and 21 rats.

105 .1 to 5,000 mug BPA/kg BW on postnatal days (PND) 1, 3, and 5.

106 cal and apoptotic changes on postnatal days (PND) 1, 3, and 7.

107 and brains were collected at postnatal days (PND) 1, 4, 8, 12, 16, 24 and 45.

108 ere depleted of serotonin on postnatal days (PND) 10-20 by treating with the tryptophan hydroxylase i

109 diation during infancy, from postnatal days (PND) 2-11 in the rat, results in severe hippocampal gran

110 On postnatal days (PND) 21, 26, or 30, rats were trained on spatial discrim

111 On postnatal days (PND) 3-15, male and female Long-Evans rats underwent 3 h

112 The pups were tested at postnatal days (PND) 35 and 56 for PPI.

113 indlimb extensors of rats on Postnatal Days (PND) 5, 10, 15, or 20, during episodes of coordinated L-

114 pups were injected daily on postnatal days (PND) 7-19, with MK-801 (MK+) or the less active isomer o

115 (5-7/group) were assessed on postnatal days (PNDs) 0, 2, 4, 7, and 19 for ER alpha (ERalpha; Esr1), b

116 Subjects were tested at postnatal days (PNDs) 0-9 and 21.

117 On postnatal days (PNDs) 1 and 3, a diffuse distribution of axons and label

118 s.c.) on alternate days from postnatal days (PNDs) 3-13 and killed on PNDs 15, 30 and 60.

119 System or to filtered air on postnatal days (PNDs) 4-7 and 10-13, and the animals were euthanized eit

120 tional age-specific risk of perinatal death (PND) can be decomposed as the product of the gestational

121 Promoted NOx decomposition (PND) technology for real-world automotive applications i

122 e paraneoplastic neurological degenerations (PNDs) are remarkable examples of naturally occurring tum

123 env chimeric clone with a partially deleted PND and did not altered the fitness of the virus in vivo

124 tract at area postrema level desynchronized PND from ventilation, eliminated the lung inflation-sync

125 d with prehospital neurologic deterioration (PND) are unknown.

126 g to the principal neutralizing determinant (PND) of human immunodeficiency virus type-1 (HIV) gp120

127 n in adults and animals late in development (PND 30-89).

128 ve in animals lesioned later in development (PND 30-89).

129 critical period of hippocampal development (PNDs 2-14).

130 d as a cause of permanent neonatal diabetes (PND).

131 rd genetics, interest in prenatal diagnosis (PND) for deafness, and preference for having deaf or hea

132 piratory responses [phrenic nerve discharge (PND) and AP] caused by injecting dl-homocysteic acid (DL

133 SND, phrenic nerve discharge (PND) and putative sympathoexcitatory vasomotor neurons o

134 rst just before the phrenic nerve discharge (PND) and rebound after inspiration (pre-I neurons).

135 sed blood pressure, phrenic nerve discharge (PND) and the firing rate of ccRTN neurons in isoflurane-

136 imol eliminated the phrenic nerve discharge (PND) at rest, during hyperoxic hypercapnia (10% CO(2)),

137 nstantly eliminated phrenic nerve discharge (PND) but normal PND could usually be elicited by strong

138 eded to inhibit the phrenic nerve discharge (PND).

139 nchronized with the phrenic nerve discharge (PND).

140 ic SNA, and rate of phrenic nerve discharge (PND; P<0.05).

141 pected paraneoplastic neurological disorder (PND) may be difficult because of the limitations of conv

142 The paraneoplastic neurologic disorders (PND) are a rare group of neurologic syndromes that arise

143 Paraneoplastic neurologic disorders (PND) are autoimmune diseases associated with cancer and

144 ment of paraneoplastic neurologic disorders (PND) include the detection of new antineuronal antibodie

145 Paraneoplastic neurologic disorders (PNDs) are believed to be autoimmune neuronal degeneratio

146 Paraneoplastic neurologic disorders (PNDs) offer an uncommon opportunity to study human tumor

147 ber concentrations (PNCs) and distributions (PNDs) in the 5-1000 nm range close to a busy roadside, c

148 acids) in the principal neutralizing domain (PND) of gp90 during the third febrile episode.

149 heterologous principal neutralizing domains (PND).

150 HIV complexes formed by anti-E-PND IgG dissociated noticeably more slowly than the comp

151 log containing electrophilic phosphonates (E-PND) neutralized a homologous HIV strain (MN) approximat

152 utralizing domain variants of groups 1 (EIAV(PND-1)) and 5 (EIAV(PND-5)), respectively; however, the

153 riants of groups 1 (EIAV(PND-1)) and 5 (EIAV(PND-5)), respectively; however, the neutralization-resis

154 ; however, the neutralization-resistant EIAV(PND-5) variant was less infectious in single-round repli

155 01 (MK-) (0.25 mg/kg), and trained at either PND 22 or 60.

156 ocked the sympathetic baroreflex, eliminated PND at rest and during chemoreceptor stimulation but did

157 tzinger region, also called CVLM) eliminated PND while increasing the stimulatory effect of CO(2) on

158 rostral ventral respiratory group eliminated PND but did not change RTN neuron response to either lun

159 roventricular (i.c.v.) kynurenate eliminated PND and the response of RTN neurons to lung inflation bu

160 atory column 1.5 mm caudal to RTN eliminated PND and the respiratory modulation of RTN neurons.

161 patient antisera to clone the genes encoding PND antigens has led to new insight into the mechanism o

162 oteins have been cloned using antiserum from PND patients.

163 ne glycol-400 (PEG-400) was given daily from PND-14 to -16, and mice were killed on PND-17 to form gr

164 (100 mg/kg) or PEG-400 was given daily from PND-17 to -19, and mice were killed on PND-20.

165 the PMCo, ERalpha expression decreased from PND 2 and remained low through PND 19.

166 atal life (PND 1-21) or throughout life from PND 1 until the end of the study.

167 tal day (PND) 15 rats but not in slices from PND 30 or 120 rats.

168 otypic explant cultures of cortex taken from PND 3 mice.

169 cipants said that they would consider having PND, and, of these, 29% said that they would prefer to h

170 h neutralizing activity against heterologous PND variants can prevent lentivirus infection and clinic

171 In PND patients, common tumors such as breast, ovarian and

172 te hypoxia promoted exaggerated increases in PND amplitude after CIH (P<0.05).

173 e effect of FK506 on CSF chemokine levels in PND patients.

174 onide were quantitated in sera of individual PND 3 pups collected 1 hr postexposure utilizing ultra-h

175 HD, before Ritalin, on PSA, after infantile (PND 2-15) exposure to x-irradiation.

176 50 mg Mn/kg/day during early postnatal life (PND 1-21) or throughout life from PND 1 until the end of

177 ted phrenic nerve discharge (PND) but normal PND could usually be elicited by strong peripheral chemo

178 an familiar shaving odors on PND 10, but not PND 14.

179 had reduced levels of PPI at PND 56, but not PND 35, suggesting the emergence of a sensorimotor gatin

180 utations are the second most common cause of PND and a rare cause of MODY.

181 tilely evoked cerebellar field potentials of PND 30-40 animals compared with neonates and adults, sug

182 We sought to determine the prevalence of PND among patients with intracerebral hemorrhage during

183 l age-specific risk of birth and the risk of PND conditional on birth at a given gestational age.

184 On PND 40, locomotor activity levels were not significantly

185 On PND's 30 and 62, animals were perfused for immunodensito

186 t for 30 d [short-term SPI (ST-SPI)], and on PND 55, we switched SPI diet to control Cas diet until a

187 the central nucleus of the amygdala (CeA) on PND 198.

188 ary tract nucleus (commNTS) had no effect on PND or SND activation by CO(2).

189 x difference was lost and then re-emerged on PND 19, with females having more than males.

190 both synaptic markers in the hippocampus on PND 30.

191 from PND-14 to -16, and mice were killed on PND-17 to form group A.

192 from PND-17 to -19, and mice were killed on PND-20.

193 ession of ERbeta in the MePD was observed on PND 0, with higher levels in females, but reversed by PN

194 cage nest to clean familiar shaving odors on PND 10, but not PND 14.

195 slower in performing the righting reflex on PND 4 and negative geotaxis compared with WKY and Spragu

196 maternal bonding in a return to dam task on PND 17 (p<0.05).

197 Rats treated with MK+ or MK- and trained on PND 22 were significantly impaired in PSA when compared

198 tnatal day (PND) 25 in rats either weaned on PND 21, or left with their mother until PND 25 (non-wean

199 n clusters than in the intercluster zones on PND 6.

200 we separated pups from dams once each day on PNDs 2-14 and recorded in vitro at PNDs 15-21.

201 rom postnatal days (PNDs) 3-13 and killed on PNDs 15, 30 and 60.

202 time with the dam during the active phase on PNDs 15-17 (p<0.05) and experienced decreased maternal b

203 Peak PNDs appeared at approximately 12 nm, showing an unusual

204 Preweanling (PND 17-18) rats, which suffer such hippocampal granule-c

205 Young Sprague Dawley rats (PND 21) were assigned to environmentally enriched, pair-

206 mid-adolescent (PND 35), or adult male rats (PND 70) were surgically implanted with a guide cannula a

207 rapezoid nucleus (RTN) eliminated or reduced PND, respectively, but did not change the effect of CO(2

208 bryo lacking all GPI-linked proteins rescues PND migration in a dose-dependent fashion, (2) showing t

209 erebral hemorrhage, 22 patients (22%) showed PND during Emergency Medical Services transport, with a

210 tes of 43 unselected patients with suspected PND referred for FDG-PET scanning to determine how usefu

211 of small tumours in patients with suspected PND.

212 irection selectivity in animals younger than PND 35 were explained by increases in responses to the p

213 Here we report that PND patients harbor high levels of the chemokine CXCL10

214 These data suggest that PND pathfinding is accomplished by migration up a gradie

215 al in SAP- and SSP-SAP-treated rats, but the PND rate was slightly elevated in SSP-SAP-treated rats.

216 es regions, V1 to V8, with V3 containing the PND region.

217 F-binding activity, and (3) showing that the PND will migrate toward a GDNF-soaked bead in vivo, but

218 Abs from mice immunized with the PND analog containing electrophilic phosphonates (E-PND)

219 25, 0.05, 0.1, 0.15, and 0.20 mg/kg) through PND days 22-25.

220 ecreased from PND 2 and remained low through PND 19.

221 nsory cortex, from postnatal day (PND) 16 to PND 25 spine retractions exceeded additions, resulting i

222 of handling) from Postnatal Day (PND) 22 to PND 40 and determined the effects of daily low-dose admi

223 developing GE from postnatal day (PND) 7 to PND 56.

224 25 was significantly reduced as compared to PND 1 (p<0.01).

225 5 was significantly increased as compared to PND 1 (p<0.05).

226 thway and target tissue phenotypes prior to (PND 5 and PND 15) and after (PND 30 and PND 60) the peri

227 Kiss1 was not detectable until PND 11 in the anterior hypothalamus, but expression leve

228 N ERbeta levels were higher in females until PND 19.

229 Separate cohorts were maintained until PND 50 and tested for learning and memory using Morris w

230 d on PND 21, or left with their mother until PND 25 (non-weaned).

231 Animals that had opened their eyes and were PND 35 or older exhibited increased direction selectivit

232 With PND, EGR is no longer needed.

233 vident herniation seem to be associated with PND.

234 ly than control Abs from mice immunized with PND.

235 Patients with PND harbor high-titer antibodies and T cells in their se

236 In 279 patients with PND, the frequency of KCNJ11, ABCC8, and INS gene mutati

237 so activated SND in bursts synchronized with PND.

238 artment among both patients with and without PND.