ライフサイエンスコーパス: a switch from @3 to

1 imidine tract-binding protein (PTB) mediates a switch from exon 8 to 8a splicing.

2 tivated macrophages, which is accompanied by a switch from a chronic to a progressive pulmonary crypt

3 Nitrosative stress induced a switch from a contractile to a synthetic phenotype in

4 bditis elegans Par-1, in MDCK cells promotes a switch from a direct to a transcytotic mode of apical

5 The APOE pathway mediated a switch from a homeostatic to a neurodegenerative micro

6 obtained at the peak of the JHR demonstrated a switch from a mild lymphophilia to a moderate neutroph

7 Kingdom in 1988, there appears to have been a switch from a predominant genotype to a heterogeneous

8 n distribution of topoisomers, demonstrating a switch from a processive to a distributive mode of act

9 these studies show that macrophages undergo a switch from a proinflammatory to a trophic phenotype t

10 ires disease, has a biphasic life cycle with a switch from a replicative to a transmissive phenotype.

11 uggesting that immunosuppression may involve a switch from a Th1 to a Th2 alloresponse.

12 videnced by reduced T-cell proliferation and a switch from a Th1 to a Th2 phenotype.

13 ment with IL-4 prevented disease and induced a switch from a Th1-type to a Th2-type response.

14 or GAP mutant was invariably accompanied by a switch from an abnormally elongated to a more normal b

15 eractions in the solid state and resulted in a switch from an aryl sulphone to a 3-cyanopyridyl motif

16 e to placement at the second position, while a switch from an l-Lys to a d-Lys typically resulted in

17 p21(WAF-1) up-regulation is associated with a switch from methylated to acetylated histone H3 on p21

18 f MEF2A at serine-408 and, thereby, promoted a switch from sumoylation to acetylation at lysine-403,

19 A switch from quiescence to activation abolishes this co

20 catenin expression in mesenchymal cells with a switch from myogenesis to adipogenesis in vivo.

21 degradation, suppressed traction, and caused a switch from osteogenesis to adipogenesis in the absenc

22 Although there was a switch from fetal to adult HgbA0 in all populations an

23 transcription at 7-7.5 months gestation; and a switch from fetal to adult transcription, where transc

24 A switch from human fetal (gamma)-to adult (beta)-globin

25 A "switch" from oxidative phosphorylation (OXPHOS) to ae

26 rom patients with idiopathic PAH, confirming a switch from oxidative phosphorylation to aerobic glyco

27 vage of VEGFR1 occurs at valine 767 and that a switch from valine to alanine at this position prevent

28 In conclusion, cultured human HSCs undergo a switch from a fibrogenic to an inflammatory phenotype,

29 r demonstrate that neural induction triggers a switch from a poised to an active chromatin state at G

30 High extracellular osmolarity results in a switch from an adaptive to an inflammatory gene expres

31 Reduction of cellular BH4 levels resulted in a switch from an eNOS dimer to an eNOS monomer.

32 We found that a switch from an M1- to an M2-dominant response occurred

33 5.5 days postcoitum embryo cultures leads to a switch from AVE to an extraembryonic visceral endoderm

34 eduction in TCA cycle activity and indicated a switch from aerobic to anaerobic glucose metabolism in

35 dulates STAT3 and TBK1 signaling, triggering a switch from proinflammatory to anti-inflammatory respo

36 This effect is possibly due to a switch from necrotic to apoptotic cell death, ultimate

37 tical impact (CCI) injury in mice results in a switch from neuronal to astrocytic d-serine release.

38 noise in the stimuli was increased, showing a switch from direction repulsion to attraction (i.e. sm

39 is of urea displays feedback that results in a switch from acid (pH ~3) to base (pH ~9) after a contr

40 rs secreted by BM stromal cells and involved a switch from BCL2 to BCLXL-dependent cell survival.

41 A switch from red- to blueshift of the absorption freque

42 A switch from BRM to BRG1 on the alkaline phosphatase pr

43 n the thalamus and their activation promotes a switch from tonic to burst firing in vitro.

44 . bronchiseptica than B. pertussis following a switch from Bvg(-) to Bvg(+) phase conditions.

45 g the process of transformation, we observed a switch from Mad1/Max to c-Myc/Max binding to oligonucl

46 Conclusion: Toxic bile acid induces a switch from Nrf2 to c-Maf/MafG ARE nuclear binding, wh

47 Ca(2+) measurements demonstrated a switch from SR-driven to Ca(2+) influx-driven Ca(2+) t

48 rotein receptor-related protein), triggering a switch from cell adhesion to cell detachment.

49 governing histone modifications that promote a switch from cell proliferation to cell death.

50 ause their sympathetic innervation undergoes a switch from a nonadrenergic to cholinergic and peptide

51 ways and resulted in elevated serum IgE, and a switch from alternative to classical activation of mac

52 hrough G1, S and G2 phases, concomitant with a switch from coactivator to corepressor recruitment.

53 nce to AZ628 in these cells, associated with a switch from BRAF to CRAF dependency in tumor cells.

54 globin gene expression is not solely due to a switch from primitive to definitive erythropoiesis.

55 ation of Myosin-II and, in parallel, induces a switch from Arp2/3 to Diaphanous-mediated cortical act

56 lts in clones expressing both genes, whereby a switch from proliferation to differentiation can be mo

57 causes extensive mitotic defects, including a switch from monomethyl to dimethyl lysine 20 of histon

58 A switch from nocturnal to diurnal activity rhythms was

59 Here, we report a switch from nocturnal to diurnal entrainment of circad

60 de lock between two YFP proteins resulted in a switch from monovalent to divalent ferrocene interacti

61 Mutations in this promoter that cause a switch from utilization of CTP to either ATP or GTP as

62 an epithelial to mesenchymal transition and a switch from dependency on FGFR3 to ERBB family members

63 antiestrogen resistance can be conferred by a switch from predominantly ERalpha to ERbeta expression

64 ines with pyrimidines in the ESE resulted in a switch from exon inclusion to exon skipping in vivo an

65 ests that BEND3 is a key factor in mediating a switch from constitutive to facultative heterochromati

66 ablish Prox1 ablation as sufficient to cause a switch from a slow- to fast-twitch muscle phenotype.

67 Consistent with a switch from glucose to fatty acid oxidation that occur

68 brown adipose tissue and was accompanied by a switch from glycolysis to fatty acid oxidation as a so

69 A switch from expression of FGFR2IIIb to FGFR2IIIc accom

70 otch signaling and increase in PTEN promoted a switch from myoblast to fibroblast lineage, and a loss

71 Participants were patients for whom a switch from natalizumab to fingolimod was planned.

72 ng forest, with fire exclusion often causing a switch from savanna to forest.

73 ates transcriptional activation of EZH1, and a switch from GATA2 to GATA1 controls the developmental

74 the decay time of synaptic currents, whereas a switch from GluR2-lacking to GluR2-containing receptor

75 lycolysis, increased glycogen synthesis, and a switch from glucose to glutamine as the major substrat

76 gic ionotropic receptor subunits, confirming a switch from Glyalpha2 to Glyalpha1 for IPSCs and incre

77 metabolism, lipolysis, glyceroneogenesis and a switch from lactate to glycerol as substrate for gluco

78 livers exhibited reduced amino acid uptake, a switch from gluconeogenesis to glycolysis, and a decre

79 namate (CHC) or siRNA in these cells induced a switch from lactate-fueled respiration to glycolysis.

80 In vitro hyperglycemia resulted in a switch from oxidative phosphorylation to glycolysis, a

81 tive changes in cell metabolism that include a switch from oxidative phosphorylation to glycolysis, i

82 tor enriched in fast-twitch muscle, promotes a switch from oxidative to glycolytic myofiber type thro

83 Resistant cells exhibited a switch from steroid-responsive growth to growth factor

84 c mice using a neutralizing antibody induced a switch from proinflammatory to healing-associated macr

85 rs improved healing of these wounds, induced a switch from proinflammatory to healing-associated Mp p

86 Thus, HAF, by causing a switch from a HIF-1alpha- to HIF-2alpha-dependent resp

87 During postnatal development there is a switch from predominantly VGLUT2 expression to high VG

88 odel for how Hsp33 uses protein unfolding as a switch from self-recognition to high-affinity client b

89 oplasmic tyrosine phosphorylation and led to a switch from heterophilic to homophilic aggregation.

90 induced by drug exposure and was related to a switch from heterozygous to homozygous mutation of DCK

91 s) lacking TRF1, but they showed evidence of a switch from the NHEJ- to HR-mediated repair of uncappe

92 g in hippocampal pyramidal neurons undergoes a switch from depolarizing to hyperpolarizing during ear

93 Hypergammaglobulinemia was maintained with a switch from IgG2a to IgG1 predominance, but the dramat

94 A switch from cTNT exon skipping to inclusion tightly co

95 1 promonocytes that SirT1 and SirT 6 support a switch from increased glycolysis to increased fatty ac

96 ostnatal period, GABAergic responses undergo a switch from being excitatory to inhibitory.

97 (Accelerate 1) and 90% (Accelerate 2), with a switch from quinine to injectable artesunate for manag

98 We propose a complete model in which a switch from extrinsic signalling to intrinsic timing p

99 olecular orbital energy differences indicate a switch from normal to inverse electron demand upon nit

100 ng zebrafish caudal fin development, wherein a switch from allometric to isometric growth occurs.

101 the host response to infection and activate a switch from the early-to-late phase.

102 A switch from apical to lateral reproductive organ devel

103 in patients receiving prednisone may reflect a switch from carbohydrate to lipid metabolism resulting

104 acutely to altered melatonin secretion after a switch from short to long days.

105 Following a switch from high to low contrast, a neuron rapidly dec

106 y to resist detachment from the surface upon a switch from high to low flow.

107 A switch from high-fat to low-fat diet reversed these ou

108 n of exogenous Tas is sufficient to initiate a switch from latent to lytic replication.

109 sed expression of EBV BZLF1, which activates a switch from latent to lytic virus infection, and incre

110 We showed a switch from MAT1A to MAT2A expression at the transcrip

111 We showed a switch from MAT1A to MAT2A expression in human hepatoc

112 We showed a switch from MAT1A to MAT2A gene expression in human li

113 We have reported a switch from MAT1A to MAT2A gene expression in human li

114 tivation alone explains these T-cell losses, a switch from "naive" to "memory" phenotype, and certain

115 xpress FGFR2-IIIb by RNA interference caused a switch from the epithelial to mesenchymal isoform.

116 o "bipolar" diagnostic status corresponds to a switch from mono- to multistability of behavioural act

117 from hepatic induction of p53 and cyclin D1, a switch from Mnt to Myc nuclear binding to E-box, and h

118 A switch from myometrial quiescence to myometrial activa

119 interacting protein kinase 3 (RIP3) acts as a switch from apoptosis to necrosis (programmed necrosis

120 ural features of necrotic cell death suggest a switch from apoptosis to necrosis in affected neurons.

121 with the PI3K family inhibitors also led to a switch from NO-induced apoptosis to necrosis, which im

122 of the metacaspase-autophagy pathway induced a switch from vacuolar to necrotic death, resulting in f

123 A switch from net acid to net alkali secretion was seen

124 activity of Smad2/3 in late G1, resulting in a switch from endoderm to neuroectoderm potential in plu

125 For R6W Dyn A, this is likely because of a switch from opioid to NMDA- receptor signalling, while

126 ulation of PRC2 subunit composition leads to a switch from canonical silencing to non-canonical funct

127 o two cytochrome c molecules, thus mediating a switch from two-electron to one-electron transfer.

128 ring Ag, the cells become activated and make a switch from IgM to other Ig classes.

129 BLM10 expression is induced 25-fold upon a switch from fermentation to oxidative metabolism.

130 ons with permafrost thaw are associated with a switch from hydrogenotrophic to partly acetoclastic me

131 r, our results suggest that TNFalpha induced a switch from the PGD2 to PGE2 synthesis pathway by regu

132 the change in branch patterning results from a switch from developmental to physiological control of

133 with the proposal that Src activity promotes a switch from integrin binding to PIPKIgamma binding tha

134 rom attraction to repulsion is the result of a switch from Epac- to PKA-mediated signaling pathways.

135 n of undifferentiated neurites, and hence in a switch from unpolarized to polarized neuronal morpholo

136 his stalling at C:8-oxo-G can be overcome by a switch from pol delta to pols lambda, beta, or eta, al

137 A switch from estradiol negative to positive feedback in

138 d defects in thymocyte selection, leading to a switch from negative to positive selection in rlk(-)(/

139 This process requires a switch from reactive to predictive control modes, from

140 g mouse skin, where progenitor cells execute a switch from symmetric to predominantly asymmetric divi

141 the level of multicellular networks enabling a switch from baseline interneuron synchrony to propofol

142 ly transformed pre-B cells is accompanied by a switch from proteasome-dependent to proteasome-indepen

143 A switch from an antidepressant medication to psychother

144 territory underwent changes consistent with a switch from an r4 to r2 identity.

145 uggest that NMDA receptors help to implement a switch from precise firing to random firing during res

146 We conclude that secretory granules undergo a switch from unregulated to regulated secretory carrier

147 SIRT1 deacetylation of TopBP1, resulting in a switch from DNA replication to repair functions for th

148 n, resolution is known to be orchestrated by a switch from inflammatory to resolving lipid mediators.

149 n, and oxidative phosphorylation, leading to a switch from fermentation to respiration.

150 ya (Late Cretaceous) and was associated with a switch from bark to rock and from shady to sun-exposed

151 antidepressant nonresponders benefited from a switch from imipramine to sertraline, or vice versa, d

152 a bacterial signaling molecule that triggers a switch from motile to sessile bacterial lifestyles.

153 mpressive cases, absence of phoA resulted in a switch from asexual to sexual development (at pH 8), o

154 ts using this coreceptor was associated with a switch from NSI to SI phenotype, loss of sensitivity t

155 With M = Sr (21) or Eu (25), a switch from M-Co bonding to side-on (eta(2)) CO ligand

156 ic changes include a loss of cellularity and a switch from predominantly CD4+ CD8+ to single positive

157 Our results suggest that a switch from substrate to substrate adaptor ubiquitinat

158 In addition, a switch from Th1 to Th0 subtype was observed in prolife

159 o to mammary epithelial cells, which undergo a switch from Th1 to Th2 cytokine production upon the in

160 decrease in disease severity was not due to a switch from Th1 to Th2 predominance in rJ.M(Y135Q)-inf

161 ecular targeting of CD44 receptor to promote a switch from Th1/Th17 to Th2/regulatory T cell differen

162 This design feature promotes a switch from ferric import to the more physiological re

163 stem IIc, suggesting that Prp16p facilitates a switch from stem IIc to the mutually exclusive U2 stem

164 Nasopharyngeal colonization data showed that a switch from the ChoP(-) to the ChoP(+) phenotype was o

165 tein from Epstein-Barr virus (EBV) activates a switch from the latent to the lytic expression program

166 cur at the Ig heavy chain locus resulting in a switch from the membrane- to the upstream secretory-sp

167 tch pathway stops proliferation and promotes a switch from the mitotic cycle to the endocycle.

168 n) to compute the optimal target latency for a switch from the short- to the long-latency location.

169 iminated dendritic calcium spikes and caused a switch from regular bursting to tonic firing or irregu

170 minished down-regulatory factors rather than a switch from type 2 to type 1 immune responses.

171 ion of HIV disease is often characterized by a switch from R5 to X4 HIV type 1 (HIV-1) variants.

172 There is a switch from Broad complex Z2 to Z1 zinc-finger isoform