ライフサイエンスコーパス: allostimulatory

1 Moreover, their allostimulatory abilities are impaired compared with tho

2 kocyte reactions were performed to assess DC allostimulatory ability and also the function of putativ

3 transduced ODN DCs exhibit markedly impaired allostimulatory ability and promote apoptosis of activat

4 gel shift assay results, and showed reduced allostimulatory ability of the CsA-treated cells compare

5 , adenosine-differentiated DCs have impaired allostimulatory activity and express high levels of angi

6 They exhibit very poor allostimulatory activity and similar migration character

7 mined by flow cytometric analysis, and their allostimulatory activity assessed in primary mixed leuko

8 iated with marked impairment of their T-cell allostimulatory activity but with only modest prolongati

9 panded CD34+-selected cells showed increased allostimulatory activity compared to both cultured CD34+

10 0, CD80, CD86, and IAb, and augmented T cell allostimulatory activity compared with controls.

11 s) from PD-L1(-/-) mice exhibited a stronger allostimulatory activity compared with that in wild-type

12 ing DC differentiation significantly reduced allostimulatory activity in a MLR using naive CD4(+) T c

13 howed pronounced impairment (>80%) of T-cell allostimulatory activity in vitro.

14 In addition, PorB not only enhanced the allostimulatory activity of DC, but also augmented the a

15 nd CD86 expression and up-regulated the poor allostimulatory activity of the DCp assessed by MLR and

16 Allostimulatory activity of the gene-transduced DCp was

17 and costimulatory molecules and naive T cell allostimulatory activity than migratory wild-type (wt) C

18 costimulatory molecules (CD80 and CD86) and allostimulatory activity than those from controls.

19 Their allostimulatory activity was assessed in vitro by MLR an

20 Their allostimulatory activity was further diminished by addit

21 /CD14- cells, a 42-fold increase (median) of allostimulatory activity was observed as compared with s

22 nistration and the resulting augmentation of allostimulatory activity within host lymphoid tissue, is

23 ndocytosis properties, cell surface markers, allostimulatory activity, and cytokine production follow

24 acity to produce IL-12, did not acquire full allostimulatory activity, and rapidly underwent apoptosi

25 rIL-4 were functionally immature in terms of allostimulatory activity, but this activity increased af

26 immature phenotype was linked to poor T cell allostimulatory activity, indicative of DC progenitors.

27 immature DCs partially restored the reduced allostimulatory activity, whereas alcohol given only dur

28 There was impaired allostimulatory activity.

29 icient in IFN-gamma still exhibited vigorous allostimulatory activity.

30 deed, Stat4(-/-) DC similarly displayed poor allostimulatory activity.

31 uclear translocation of RelB, and developing allostimulatory activity.

32 sed the impact of transgene expression on DC allostimulatory activity.

33 g HLA-DR, CD1a, CD83, CD80, CD86, and potent allostimulatory activity.

34 They also possess substantial phagocytic and allostimulatory activity.

35 nd epidermal cell suspensions were devoid of allostimulatory activity.

36 tolerogenic role of immature DC, the T cell allostimulatory and Th1-biasing function of CD14+ LC pre

37 rAd-transduced DC exhibited increased allostimulatory capacity and levels of interleukin-6 (IL

38 crophages, but acquire, upon maturation, the allostimulatory capacity and surface phenotype of classi

39 from gammadelta-/- recipients exhibited less allostimulatory capacity compared to wt DCs after irradi

40 L-treated animals exhibited increased T cell allostimulatory capacity compared with controls.

41 nally by production of IL-12 and an enhanced allostimulatory capacity in a MLR.

42 Reduced allostimulatory capacity in HCV core- and NS3-treated im

43 of IL-10, during MLR ameliorated the reduced allostimulatory capacity of alcohol-treated DCs.

44 In summary, lack of CCR2 interferes with the allostimulatory capacity of DC and promotes the generati

45 on and G-CSF mainly acted on the suppressing allostimulatory capacity of DCs.

46 We have separated the allostimulatory capacity of endothelium from that of hem

47 lta T cells exacerbate GVHD by enhancing the allostimulatory capacity of host antigen-presenting cell

48 d NS3 (not E2) inhibited differentiation and allostimulatory capacity of immature DCs similar to defe

49 T-cell allostimulatory capacity of the DC, including DC exposed

50 cal to that of interdigitating DC and potent allostimulatory capacity were released from FSDDC-A with

51 d costimulatory molecule expression and poor allostimulatory capacity when interacting with T cells,

52 loci in germline configuration and show low allostimulatory capacity, but produce type I IFN upon vi

53 ich are markedly impaired in Foxp3(-) T cell allostimulatory capacity, to favor the stimulation of mu

54 oglobulin (Ig) production, and CD4(+) T-cell allostimulatory capacity.

55 mitigated the enhanced in vitro and in vivo allostimulatory capacity.

56 dy weight) in normal volunteers inhibited DC allostimulatory capacity.

57 ion of proinflammatory cytokines, and T-cell allostimulatory capacity.

58 edly lowered rate of Ag uptake and increased allostimulatory capacity.

59 (CD40, CD80, CD86), and MHC class II Ag, and allostimulatory capacity.

60 cipients of islet allografts, display lesser allostimulatory capacity.

61 es exhibited dendritic morphology and potent allostimulatory capacity.

62 tial augmentation of the number of potential allostimulatory cells in donor organs before transplanta

63 and CD40 cross-linking increased the T-cell allostimulatory function of BM DCs, only LPS stimulation

64 The allostimulatory function of DCs was assessed by mixed le

65 s C virus (HCV) has been shown to affect the allostimulatory function of DCs.

66 a time-dependent manner and were capable of allostimulatory function.

67 phenotype, and mixed lymphocyte reaction for allostimulatory function.

68 Consequently, the allostimulatory functions of DCs were impaired by TPT tr

69 PS was superior to CpG ODN in increasing the allostimulatory potential of lung DCs and their expressi

70 d CD80, and reduced the in vitro and in vivo allostimulatory responses induced by the DCs.

71 Thus, although normal livers provide allostimulatory signals sufficient to elicit an antidono

72 ory and maturation molecules induce a robust allostimulatory T-cell response.

73 These data suggest that some allostimulatory white cells are filter adherent, whereas