ライフサイエンスコーパス: casein

1 ere potent GLP-1 secretagogues (except kappa casein).

2 ein, 5 from alphaS2-casein, and 4 from kappa-casein.

3 ost 3.2 times more than A1A2 variant of beta-casein.

4 tection levels of 2microgmL(-1) for alpha-S1-casein.

5 ld not be detected from A2A2 variant of beta-casein.

6 e epitope in alphas1 -casein to 73% in kappa-casein.

7 ed, one from alphaS1-casein and 17 from beta-casein.

8 zed casein was negligible compared to native casein.

9 The fragment alphaS1-casein (1-23) is an immunomodulatory and antimicrobial p

10 n (193-202), alphas1-casein (85-91), alphas1-casein (1-9), as well as alphas2-casein (189-197) have a

11 ryptic digest with bovine serum albumin (BSA:casein, 100:1).

12 1), alphas1-casein (1-9), as well as alphas2-casein (189-197) have antihypertensive activity.

13 The peptides beta-casein (58-72), beta-casein (193-202), alphas1-casein (85-91), alphas1-casein

14 -casein, 4 from betaA2-casein, 4 from betaA3-casein, 25 from alphaS1-casein, 5 from alphaS2-casein, a

15 nt peptides; 74 of them originated from beta-casein, 4 from betaA2-casein, 4 from betaA3-casein, 25 f

16 m originated from beta-casein, 4 from betaA2-casein, 4 from betaA3-casein, 25 from alphaS1-casein, 5

17 asein, 4 from betaA3-casein, 25 from alphaS1-casein, 5 from alphaS2-casein, and 4 from kappa-casein.

18 The peptides beta-casein (58-72), beta-casein (193-202), alphas1-casein (8

19 Data for the baked cookies were as follows: casein, 84-90%; soy protein, 80-88%, and gluten, 80-90%.

20 sein (58-72), beta-casein (193-202), alphas1-casein (85-91), alphas1-casein (1-9), as well as alphas2

21 llowing recoveries based on soluble protein: casein, 95-107%; soy protein, 92-97%, and gluten, 96-99%

22 - 0.8 g/L and C1 = 2.0 +/- 0.7 g/L and kappa-casein A = 1.6 +/- 0.3 g/L and B = 1.1 +/- 0.2 g/L.

23 mount of each casein per allele was: alphas2-casein A = 2.9 +/- 0.8 g/L and F = 1.8 +/- 0.4 g/L; beta

24 sponding reduction in the production of beta-casein, a milk protein.

25 The relative sizes of the casein aggregates were governed by the concentration of

26 proteins present a physical barrier to para-casein aggregation.

27 f sodium caseinate (NaCN) and purified alpha-casein (alphas-CN) with an Aspergillus niger derived pro

28 hey proteins partially reassociated with the caseins, although a complex behaviour was observed at ap

29 f AI-ETD in localizing phosphosites in alpha-casein, an approximately 23.5 kDa phosphoprotein that sh

30 AcPs was preferentially active towards kappa-casein, analysed by Urea-PAGE and LC-ESI-MS, whereas the

31 d peptides were identified, one from alphaS1-casein and 17 from beta-casein.

32 diet with 20% casein (control group) or 15% casein and 5% of peptide fractions (treatment groups E1,

33 duplex ASV-QDs-based determination of bovine casein and bovine immunoglobulin G is carried out in mil

34 dissociation and the concentrations of kappa-casein and denatured whey protein in the serum, and a re

35 This resulted in different levels of casein and denatured whey proteins to be distributed bet

36 ein hydrolysates derived from tilapia mince, casein and pea protein, were investigated.

37 gene expression compared with non-hydrolyzed casein and pea protein.

38 Casein and soy protein HPDs did not induce inflammation,

39 d samples up to concentrations of 10 ppm for casein and soy protein, and 100 ppm for gluten.

40 of milk and its major components, alpha/beta-casein and whey acidic protein (WAP), is significantly r

41 uman jejunal digests after oral ingestion of casein and whey protein were collected by a nasogastric

42 t amount of iron due to the presence of both casein and whey protein.

43 or free oligosaccharides, fatty acids, major casein and whey proteins, and milk fat volatiles.

44 rgens (alphas1 -, alphas2 -, beta- and kappa-caseins and beta-lactoglobulin) in paired maternal and i

45 On acidification to pH 5.4, the serum phase caseins and denatured whey proteins partially reassociat

46 At pH below 5.4 the caseins and denatured whey proteins rapidly aggregated.

47 act simultaneously with phosphoserine on the caseins and inorganic phosphorus.

48 n this study, structural changes in micellar caseins and whey proteins due to high pressure--low temp

49 milk components (milk fat, xanthine oxidase, caseins and whey proteins) in pulsed electric field (PEF

50 quillaja saponin, Tween 80, whey protein and casein) and antioxidant type (EDTA, ascorbic acid, catec

51 t individual proteins (alpha, beta and kappa casein) and hydrolysates on an enteroendocrine cell line

52 n with enamel (e.g., compared with mucin and casein) and significantly reduced initial enamel erosion

53 sein, 25 from alphaS1-casein, 5 from alphaS2-casein, and 4 from kappa-casein.

54 , hemoglobin, bovine serum albumin, and beta-casein, and compare the results with enzymatic digestion

55 The enzyme hydrolyzed casein, and the hydrolysate inhibited the growth of Esch

56 lmost total degradation of alphas1- and beta-casein (approximately 90%).

57 to enteroendocrine cells, and alpha and beta casein are particularly beneficial stimulating prolifera

58 ate with iron in the presence and absence of caseins are postulated, and new mechanisms are proposed.

59 The current view is that caseins are secreted by exocytosis, whereas milk fat glo

60 d on the Michaelis-Menten plots, the Km with casein as substrate was 16.8muM and Vmax was 82.6muM/min

61 developed for allergens analysis using alpha-casein as the biomarker for cow's milk detection, to be

62 onstrated good selectivity towards the alpha-casein as the target analyte and adequate recoveries fro

63 red to whey proteins, with less digestion of casein at pH 3.0 than at pH 5.0.

64 during small-scale manufacture of semi-solid casein-based food matrices was investigated and found to

65 allow matrix formation during manufacture of casein-based food structures e.g. processed and analogue

66 n modulating hydration during manufacture of casein-based matrices than simply solubilising calcium o

67 main important result was obtained for kappa-casein because, till now, no data were available on quan

68 .9 +/- 0.8 g/L and F = 1.8 +/- 0.4 g/L; beta-casein C = 3.0 +/- 0.8 g/L and C1 = 2.0 +/- 0.7 g/L and

69 s2-casein genetic variants A and F, and beta-casein C and C1 with other previously described method.

70 e, and reductions in concentrations of serum casein, Ca and P.

71 down more slowly than the others because the caseins clotted at the gastric pH.

72 isolate (WPI), soy protein isolate (SPI) and casein (CN) and their binary mixtures, viz., WPI+SPI, WP

73 k proteins, beta-lactoglobulin (beta-LG) and casein (CN) was greatly diminished with gastric simulati

74 3 on heme and heme+purified animal protein (casein, collagen, albumin).

75 Study 3: casein, collagen, and albumin did not affect the bioavai

76 S, whereas the degradation of alpha and beta-casein components by AcPs proceeded slowly justifying it

77 obulin were found in the two PH formulas and casein components in one of the EH formulas.

78 One PH formula and the EH formula containing casein components showed remaining IgE reactivity, where

79 Pepsin diffusion in rennet gels depends on casein concentration and microstructure.

80 re measured in rennet gels across a range of casein concentrations allowing to form networks of prote

81 ein:casein (WP:CN) ratios (with standardised casein concentrations) were made from powders produced b

82 the late 1800s when it was demonstrated that casein contains phosphate.

83 ps of mice were fed a high-fat diet with 20% casein (control group) or 15% casein and 5% of peptide f

84 fed six protein diets for 14 days, including casein (control), and proteins isolated from soy, fish,

85 No separate aggregation of kappa-casein/denatured whey protein complexes or kappa-casein

86 in/denatured whey protein complexes or kappa-casein depleted micelles was observed.

87 The occurrence of the casein-derived angiotensin converting enzyme-inhibitor (

88 Other reports on the bioactivity of casein-derived peptides have shown that the beta-casein

89 Compared with the casein diet, the soy protein diet had a similar oxidatio

90 el CaCl2 solutions (50 mmol L(-1)) or rennet casein dispersions (15 g/100 g).

91 helating salt-calcium interactions in rennet casein dispersions.

92 pH before heat treatment led to increases in casein dissociation and the concentrations of kappa-case

93 ved at approximately pH 5.4 where additional casein dissociation occurred in some samples.

94 This study demonstrates and explains how casein-enriched retentates from microfiltration gel fast

95 Previous studies suggest that casein exerts various anti-diabetic effects.

96 mounts emptied faster than predominant whole casein feeds and one study found no difference in GE.

97 species of cytochrome C, lysozyme, and beta-casein formed during glycation with d-glucose were ident

98 administration of an extensively hydrolyzed casein formula (EHCF) containing the probiotic Lactobaci

99 Casein fractions were kept intact under a heat treatment

100 hosphate and the aggregates consisted of all casein fractions, even at the lowest level of ferric chl

101 in the hydrolysis of the alpha-s2 and kappa-casein fractions.

102 to be more efficiently digested compared to caseins from cow milk and peptide profiles from goat mil

103 Caseins from goat milk tended to be more efficiently dig

104 The yield of BCM-7 (0.20+/-0.02mg/g beta-casein) from A1A1 variant was observed to be almost 3.2

105 id chromatographic (HPLC) method to quantify casein genetic variants (alphas2-, beta-, and kappa-case

106 was found between the quantities of alphas2-casein genetic variants A and F, and beta-casein C and C

107 d highly suitable for quantification of goat casein genetic variants of homozygous individuals.

108 as to evaluate the effect of the presence of casein glycomacropeptide (CMP) on the in vitro digestibi

109 tein group showed lower Grx1 levels than the casein group and the beef protein group showed the highe

110 om +13 to +17 positive charges, whereas beta-casein had charge states up to +30.

111 mmuno-reactivity of whey protein isolate and casein has been studied.

112 ole of calcium chelating salts in modulating casein hydration and dispersion and gives an indication

113 Anti-inflammatory activity was observed in casein hydrolysate (CH) and pea protein hydrolysate (PPH

114 all cases) but entrapment was lower for the casein hydrolysate (circa 50%), possibly indicating a ph

115 confidence interval, 0.81-21.02) between the casein hydrolysate and cow's milk groups.

116 fants were randomly assigned to groups fed a casein hydrolysate formula (n = 113) or a conventional f

117 ), whey protein isolate (WPI), insulin and a casein hydrolysate were entrapped in chitosan-polyphosph

118 Peptides from casein hydrolysate were partially (circa 35%) but quickl

119 uring digestion of repolymerized thermolysin-casein hydrolysates had no immuno-reactivity.

120 Only pepsin-derived beta casein hydrolysates had significantly increased potency

121 tide, VLPVPQK (named peptide C) derived from casein hydrolysates was investigated along with extensiv

122 n these alternative hypotheses, we performed casein hydrolysis assays to measure the SpeB protease ac

123 The protease preparations displayed similar casein hydrolysis kinetics and were active in hydrolysin

124 e whey hydrolyzate (pHF-W, eHF-W), extensive casein hydrolyzate (eHF-C) or standard cow's milk formul

125 e sought to characterize immune responses to casein in children with FPIES caused by cow's milk (CM).

126 ess of the type of salt added, the amount of casein in milk serum decreased and the amount of calcium

127 tprandial chylomicron response compared with casein in persons with abdominal obesity, thereby indica

128 is hypothesised that the addition of iron to caseins in the presence of orthophosphate results in the

129 genetic variants (alphas2-, beta-, and kappa-casein) in milk of homozygous individuals of Girgentana

130 IL-4 synthesis when stimulated with casein increased significantly in subjects who are react

131 in hyperglycemia and glucose intolerance in casein-injected mice.

132 s, C2C12 myoblasts and 3T3-L1 adipocytes and casein injection in C57BL/6J mice to induce inflammatory

133 and hyperlipidemia regardless of exposure to casein injection, only the HFD+Casein mice showed increa

134 study evaluated the effects of intact whole casein, intact individual proteins (alpha, beta and kapp

135 food proteins, such as beta-lactoglobulin or caseins, intensely studied for bioactive peptide product

136 orthophosphate, causing re-dispersion of the casein-iron complexes.

137 entrations of orthophosphate solution to the casein-iron precipitates resulted in gradual adsorption

138 Casein-iron precipitates were formed by adding ferric ch

139 ored the interactions of orthophosphate with casein-iron precipitates.

140 The re-dispersed soluble complexes of casein-iron-orthophosphate generated using this process

141 formation of colloidal structures involving casein-iron-orthophosphate interactions.

142 g peptide, we established a pivotal role for casein kinase (CK)-2-mediated circadian BMAL1-Ser90 phos

143 y mechanistic target of rapamycin (mTOR) and casein kinase (CSNK)-2.

144 ubiquitylation were blocked by disruption of casein kinase 1 (CK1) activity, and mass spectrometry an

145 such as phosphorylation of clock proteins by casein kinase 1 (CK1) and glycogen synthase kinase 3 (GS

146 We also show casein kinase 1 (Hrr25) is a key kinase that phosphoryla

147 Strikingly, loss of casein kinase 1 activity causes constitutive activation

148 protein stability of FOXO3A is regulated by Casein Kinase 1 alpha (CK1alpha) in an oncogenic RAS-spe

149 Depletion of casein kinase 1 gamma (CSNK-1) in Caenorhabditis elegans

150 in 90 and glycogen synthase kinase 3 but not casein kinase 1 nor LATS in YAP-mediated TAZ loss.

151 iotic division is coordinated by a conserved casein kinase 1.

152 clock, a protein complex of frequency (FRQ), casein kinase 1a (CK1a), and the FRQ-interacting RNA Hel

153 t lenalidomide induces the ubiquitination of casein kinase 1A1 (CK1alpha) by the E3 ubiquitin ligase

154 and metastasis in vivo via downregulation of casein kinase 1alpha (CK1alpha), a suppressor of pro-met

155 Here we report that casein kinase 1alpha (CK1alpha), a ubiquitously expresse

156 nhibitor), adenomatous polyposis coli (APC), casein kinase 1alpha (CK1alpha), and glycogen synthase k

157 inc finger proteins 1 (IKZF1) and 3 (IKZF3), casein kinase 1alpha (CK1alpha), and the translation ter

158 IFN in the context of intestinal knockout of casein kinase 1alpha (CK1alpha), which controls the ubiq

159 mor suppressor adenomatous polyposis coli or casein kinase 1alpha uncovered new regulatory features a

160 Casein kinase 1delta (CK1delta) family members associate

161 89, while also enhancing Sid4's affinity for casein kinase 1delta (CK1delta).

162 ermined whether pharmacological targeting of casein kinase 1delta and epsilon (CK1delta/epsilon), key

163 Casein kinase 1delta/epsilon (CK1delta/epsilon) and thei

164 In the present study, we found that casein kinase 1epsilon (CK1epsilon) was increased signif

165 its vulnerability to degradation mediated by casein kinase 1epsilon (CSNK1E) is increased.

166 earing a short-period mutation in the enzyme casein kinase 1epsilon (tau mutation), which accelerates

167 Here, we show that fission yeast Cki3 (a casein kinase 1gamma homolog) is a critical regulator to

168 es with thapsigargin (10 mum), inhibition of casein kinase 2 (4,5,6,7-tetrabromobenzotriazole; 10 mum

169 effects of mutant M1 spastins on FAT involve casein kinase 2 (CK2) activation.

170 Casein kinase 2 (CK2) binds to the NHE3 C-terminus and c

171 7 -: tetrabromobenzotriazole (TBB), a potent casein kinase 2 (CK2) inhibitor, as a strong suppressor

172 The protein kinase casein kinase 2 (CK2) is a pleiotropic and constitutivel

173 Although protein kinase casein kinase 2 (CK2) is readily detected in MKs and pla

174 Previous research suggests that casein kinase 2 (CK2) may be a promising therapeutic tar

175 Previous in vitro studies indicated that casein kinase 2 (CK2) mediated the phosphorylation of NS

176 We have previously shown that casein kinase 2 (CK2) negatively regulates dopamine D1 a

177 The MRE11-PIH1D1 interaction is dependent on casein kinase 2 (CK2) phosphorylation of two acidic sequ

178 The Foxc2 amino terminus has a consensus casein kinase 2 (CK2) phosphorylation site at serine 124

179 and overexpression experiments, we show that casein kinase 2 (CK2) promotes stress granule dynamics.

180 ctivated through pharmacologic inhibition of casein kinase 2 (CK2) to eradicate disease in high-risk

181 ere, we report that Brg1 is also a target of casein kinase 2 (CK2), a serine/threonine kinase, in pro

182 wn previously to require the Cka2 subunit of casein kinase 2 (CK2), a ubiquitous enzyme with multiple

183 on was dependent on XRCC1 phosphorylation by casein kinase 2 (CK2), enhancing XRCC1's interaction wit

184 on events catalyzed first by MEK and then by casein kinase 2 (CK2), followed by interaction with impo

185 e, and this phosphorylation was catalyzed by casein kinase 2 (CK2), the levels of which were dramatic

186 We have also noted that casein kinase 2 (CK2)-directed phosphorylation of Pax7 a

187 various kinases, including GPCR kinases and casein kinase 2 (CK2).

188 Casein kinase 2 alpha phosphorylates PDCD5 at Ser-119 to

189 posttranslationally regulated by TNF-induced casein kinase 2 catalytic subunit (CK2alpha') phosphoryl

190 These data support a role for casein kinase 2 in regulation of protein synthesis by do

191 Upon hypertrophic stimuli, casein kinase 2 phosphorylates DPF3a at serine 348.

192 We also show that casein kinase 2 phosphorylates G3BP1 at serine 149 in vi

193 This activity, and the ability of casein kinase 2 to use GTP as a phosphate donor, may be

194 ine 424 by protein kinase CK2 (also known as casein kinase 2) activated the HDAC3 in vitro.

195 overed that murine Arl13b is a substrate for casein kinase 2, a contaminant in our preparation from h

196 ation of ErbB2 or loss of the betasubunit of casein kinase 2, shifted the whole population toward a f

197 uired Rab11-dependent trafficking and FAM20C/casein kinase 2-dependent C-terminal phosphorylation of

198 required for insulin induction of Sort1 in a casein kinase 2-dependent manner and that inhibition of

199 Casein kinase 2-mediated phosphorylation at VHL N-termin

200 e U.S. Food and Drug Administration-approved casein kinase activator, pyrvinium) in C57Bl/6J mice res

201 NUCKS1 (nuclear casein kinase and cyclin-dependent kinase substrate 1) i

202 Activating beta-catenin through Casein Kinase I inhibition or Wnt3A addition increased b

203 When HOPS is phosphorylated by the vacuolar casein kinase I, Yck3p, tethering only takes place when

204 Set8 for ubiquitination and degradation in a casein kinase I-dependent manner, which is activated by

205 Casein kinase Ialpha (CKIalpha) directly phosphorylated

206 Following these changes, loss of Casein kinase Ialpha and induction of chronic DNA damage

207 -dione derivatives were synthesized as human casein kinase II (CK2) inhibitors.

208 roaches, we have identified a novel role for casein kinase II (CKII) in the modification of the polym

209 ed the phosphorylation of Dgk1 DAG kinase by casein kinase II (CKII).

210 s work, we show that Pah1 is a substrate for casein kinase II (CKII); its phosphorylation was time- a

211 this repression by directly interacting with Casein Kinase II and preventing it from activating HDAC3

212 phosphatase calcineurin (TAX-6), and of the casein kinase II homologue KIN-10.

213 ously reported that the protein kinase C and casein kinase II substrate in neurons (PACSIN) forms a c

214 In this study, we determined the role of casein kinase-1 (CK1) in regulating NMDAR activity in th

215 Arsenite also recruited a TDP-43 kinase, casein kinase-1 (CK1), to GADD34.

216 ut not other PI3Kdelta inhibitors, inhibited casein kinase-1 epsilon (CK1epsilon).

217 We show that casein kinase-1 inhibition increases NMDA receptor activ

218 Our data indicate that casein kinase-1 tonically regulates NMDA receptor activi

219 liver nuclei all three PERs, both CRYs, and Casein Kinase-1delta (CK1delta) are present together in

220 Conversely, casein kinase-2 (CK2)-inhibitor increases Ikaros functio

221 s NMDA receptor activity by interacting with casein kinase-2 and protein phosphatases in the hypothal

222 clear translocation of PER2 are regulated by casein kinase.

223 ity 20C (Fam20C), is the physiological Golgi casein kinase.

224 Dual mutation of Ser1700 and a nearby casein-kinase II site (Thr1704) caused accelerated hyper

225 nase ataxia-telangiectasia-mutated (ATM) and casein kinase1 (CK1) and casein kinase2 (CK2) positively

226 a-mutated (ATM) and casein kinase1 (CK1) and casein kinase2 (CK2) positively and negatively regulates

227 The yeast casein kinases (Ycks) are key players in this pathway.

228 We report here that the redundant casein kinases Yck1p and Yck2p phosphorylate sites withi

229 We have addressed this question in the casein locus containing five mammary and two non-mammary

230 t only one out of the four CTCF sites in the casein locus had a measurable in vivo activity.

231 ult1d1 promoter and several enhancers in the casein locus.

232 Measurements of casein macro peptide release showed that native whey pro

233 isolate (WPI) solutions as well as micellar casein (MC) dispersions and mixtures were treated at 500

234 noblends were synthesized to detect micellar casein (MC), the main milk protein and an indicator of m

235 f exposure to casein injection, only the HFD+Casein mice showed increased hepatic vacuolar degenerati

236 hey protein in the serum, and a reduction in casein micelle size (P<.05).

237 tein with the casein micelle, an increase in casein micelle size, and reductions in concentrations of

238 sociation of denatured whey protein with the casein micelle, an increase in casein micelle size, and

239 was not different for vitamin D-re-assembled casein micelles and control fortified milks after 21days

240 erstand the physicochemical modifications of casein micelles induced by Ser2 and to confirm its impli

241 min D was retained in vitamin D-re-assembled casein micelles than control powders during storage, whi

242 In conclusion, re-assembled casein micelles with high loading efficiency show promis

243 fat-soluble vitamin loading in re-assembled casein micelles, and to evaluate vitamin D stability of

244 r network with the presence of aggregates of casein micelles.

245 ivity with alpha2-macroglobulin but not with casein or Cm-Tf.

246 s markedly defective in cleaving bovine beta-casein or the natural CTRC substrates human cationic try

247 (P = 0.034), beta-lactoglobulin (P = 0.010), casein (P = 0.047) and lactoferrin (P = 0.030) during tr

248 , particularly in areas of alpha-s- and beta-casein (P<.01, false discovery rate [FDR]<.1).

249 in-derived peptides have shown that the beta-casein peptide (193-209) exhibits immunomodulatory, anti

250 The amount of each casein per allele was: alphas2-casein A = 2.9 +/- 0.8 g/

251 new system was applied for the enrichment of casein phosphopeptides from a simulated tryptic digest w

252 ial of iron fortified goat and cow milks and casein phosphopeptides obtained from each species of mil

253 old sensor chip was used to immobilise alpha-casein-polyclonal antibody using EDC/NHS coupling proced

254 Combinatorial perturbations to dietary casein protein and psyllium fiber in parallel accounted

255 The extra-casein protein sample matrix broke down more slowly than

256 However, it is not known which casein proteins are bioactive, nor their effects on ente

257 In conclusion casein proteins are not detrimental to enteroendocrine c

258 vitro gastric digestion behavior of whey and casein proteins in a heat-treated semisolid real food.

259 s less phosphorus and potassium than soy and casein proteins, as a supplemental protein source for MH

260 Caseins reacted to pH changes differently compared to wh

261 moieties were observed for lysozyme and beta-casein, respectively in various heating conditions.

262 Furthermore, supplementation with casein resulted in a significant increase in the postpra

263 The results for beta-casein revealed favored cleavage of the Glu-X bond at su

264 differed only regarding protein source, with casein serving as reference.

265 The results for phosphoprotein beta-casein show that, under mild subcritical water condition

266 Beta casein significantly stimulated enteroendocrine cell pro

267 coveries of 91-108%, 88-127% and 85-108% for casein, soy protein and gluten, respectively.

268 eived a 3-wk isocaloric supplementation with casein, soy protein, or maltodextrin as a control.

269 il CD63 expression and histamine release and casein-specific CD4(+) regulatory T-cell proliferation.

270 Total IgE and IgM, CM-specific IgG, and casein-specific IgE, IgG, IgG4, and IgM levels, as well

271 We found low levels of CM and casein-specific IgG and casein-specific IgG4 in patients

272 low levels of CM and casein-specific IgG and casein-specific IgG4 in patients with CM-FPIES versus th

273 ion of IL-10 and higher secretion of IL-9 by casein-stimulated T cells were found in patients with CM

274 response and TH2 cytokines production after casein stimulation in children with CM-FPIES, results we

275 omplexation of C3G molecules in the internal casein structure.

276 Proliferating casein/T-effector cell counts were measured in children

277 ike protease that can generate peptides from casein that have a bacteriostatic effect.

278 were more resistant to pepsin digestion than caseins; this is related with a higher satiety capacity.

279 irs sharing at least one epitope in alphas1 -casein to 73% in kappa-casein.

280 evaluation of its ability to hydrolyze milk casein to generate antimicrobial peptides.

281 ics and were active in hydrolysing BODIPY-FL casein to varying extents at postmortem aging meat pH (5

282 beta-Casein variants (A1A1, A1A2 and A2A2) were isolated from

283 No intact casein was detected in the jejunal nor in the in vitro s

284 mic this dynamic passivation mechanism, beta-casein was encapsulated into GUVs, yielding a stable, hi

285 o-reactivity of hydrolyzed and repolymerized casein was negligible compared to native casein.

286 The degree of hydrolysis (DH) of casein was observed to be the highest throughout the cou

287 ore proteolytic than chymosin and that kappa-casein was proteolyzed.

288 ling revealed that the AcPs activity on milk casein was similar to that of a commercial milk coagulan

289 imal loading of vitamin D (1.38-1.46mg/100mg casein) was found at 4.9mM phosphate, 4.0mM citrate and

290 Using a model substrate (casein), we report cryo-electron microscopy structures a

291 s from bovine beta-lactoglobulin and alphaS1 casein were identified as suitable peptide markers of mi

292 o protein isolates; bovine serum albumin and casein were investigated for their available lysine cont

293 Caseins were hydrolyzed in the preferential order beta->

294 ry, numerous released peptides from the four caseins were identified at the end of storage.

295 d enteroendocrine cell proliferation and all caseins were potent GLP-1 secretagogues (except kappa ca

296 protein) on iron-induced aggregation of the caseins were studied at pH 6.8.

297 fraction B of A1A1 and A1A2 variants of beta-casein with elastase and leucine aminopeptidase revealed

298 Milks with a wide range of whey protein:casein (WP:CN) ratios (with standardised casein concentr

299 Casein zymography and Western blot of m-calpain were per

300 quid-liquid extraction technique followed by casein Zymography detection.