ライフサイエンスコーパス: change of

1 higher weighted mean difference (WMD) of BMD change of 0.01 (95% CI: 0.01, 0.02) than the control.

2 ictor of overall survival (HR for a two-fold change of 1.23, 95% CI 1.13-1.34; p<0.0001) and non-rela

3 mortality (cause-specific HR for a two-fold change of 1.24, 1.12-1.38; p<0.0001).

4 Mini-Mental State Examination (MMSE) rate of change of +1.8 points per year, whereas patients in the

5 ame hemifield that showed progression with a change of -1 dB/year or more (P < 0.01) for inner points

6 Our results are based on the areal changes of 121 deltas since the 1940s, assessed using ne

7 Here, we investigate whether changes of (13)C/(12)C, (2)H/(1)H, and (15)N/(14)N ratio

8 ry alloys were capable of generating entropy changes of 14 J kg(-1) K(-1) or 22 J kg (-1) K(-1), and

9 Detecting a population change of 15% or less requires a large number of sites t

10 Sepsis-3 Criteria emphasized the value of a change of 2 or more points in the Sequential [Sepsis-rel

11 shold of pFDR < 0.05, 3 RNAs exceeded a fold change of 2.

12 42 sites showed significant DNA methylation changes of 2% or greater.

13 range of temperatures, hydrostatic pressure changes of 2.5 kbar yield large and reversible barocalor

14 ually divergent results with an MMSE rate of change of -3.2 points per year.

15 eline competition were associated with price changes of -31.7% (95% CI, -34.4% to -28.9%), -11.8% (CI

16 The shape-change of 3D printed smart materials adds an active dime

17 re variable, with a mean relative percentage change of 94.7% (SD= 195.7; range, 4.3-1155.4%) from pre

18 tures by utilising the liquid to solid phase change of a composite hydrogel (CH) ink.

19 norhabditis elegans In in vitro experiments, change of a conserved lysine (K) that is involved in ATP

20 most existing methods only model the overall change of a gene set, yet completely overlooked heteroge

21 ivery system was mediated by physicochemical changes of a spiropyran-merocyanine photochromic dyad, w

22 The method is based on the intensity changes of a tethered fluorophore, diffusing in the expo

23 es it possible to monitor the conformational changes of a translational molecular machine during its

24 nano-ablation, we assess the spatiotemporal changes of actomyosin-dependent force and stiffness alon

25 cal stimulus involving the protonation state change of adamantane carboxylate at pH 5.8, and (3) by a

26 targets were detected by measuring the color change of AgNPs, giving detection limits of 1.53 (MERS-C

27 report for the first time the physiological changes of algal cells in response to a novel form of me

28 d in accelerated growth, along with anabolic changes of an altered metabolome.

29 The observed time-dependent light-induced changes of an avoided level crossing resonance demonstra

30 edistribute to daughter cells was not due to changes of anaphase duration or nuclear shape but solely

31 The changes of aNPP and Rs in response to drought indicated

32 s, leading to widespread relative expression changes of APA isoforms.

33 cal system theory, we investigated stability changes of APs observed in a paced human ventricular myo

34 ic pressure was used to probe conformational changes of Aquifex aeolicus dihydroorotase (DHO), which

35 The change of Asn at position 460 to His, which corresponds

36 observational phase, remission rates before change of assigned treatment were 24 of 37 (64.9%) and 1

37 However, rapid changes of astrocyte neurotransmitter uptake and morphol

38 y bias to threat in addition to a subsequent change of attention allocation.

39 olved in the repetitive movements and limbic changes of autism.

40 mia, and that VRCs provide a method to study changes of axonal membrane potential of human sympatheti

41 dinal analysis showed no overall significant change of BCVA within 12 months, but the rate of BCVA ch

42 ool to study interactions and conformational changes of biological molecules in the distance range fr

43 inetics of very short DNA and conformational changes of biomolecules with much improved temporal reso

44 c measures.No significant differences in the change of BMD, BMC, or bone area for the total-body radi

45 standardized by the amount of precipitation change) of BNPP was similar under precipitation addition

46 In rare cases, changes of body length may occur in response to harsh en

47 ion, its efficacy for clinical symptoms, and changes of brain functional imaging in SCA38 patients.

48 s knowledge by demonstrating more widespread changes of brain network organization elicited by early-

49 The study failed to detect median change of CAL-V from 1 to 5 years after surgery (median:

50 h molecular factors including conformational changes of CAMs and cellular factor including fluctuatio

51 water extracts (BE and WE) to study dynamic changes of carbonaceous, nitrogenous, and oxygenated DBP

52 he population-weighted median annual rate of change of catastrophic payment incidence was positive wh

53 e in the SR, under control of conformational changes of CaV1.1, located approximately 12 nm away in t

54 lock measuring and responding to the rate of change of cellular sucrose.

55 eral dynamic microglial processes, including changes of cellular morphology, surface phenotype, secre

56 h correlating measured ORR activity with the change of chemical bonds in precursors during thermal ac

57 crospectral images revealed the distribution changes of chemical components on the fiber bundle surfa

58 ents had a wide range of individual rates of change of choroidal thickness, from -20.00 to 17.09 mum/

59 Our results reveal dynamic changes of chromatin accessibility in adult mammalian br

60 e I hypersensitive site sequencing) to study changes of chromatin accessibility in euchromatic and he

61 D We used RNA sequencing to study expression changes of circulating microRNAs in a discovery sample o

62 to climate change alone and due to combined changes of climate and the growth form and biomass of ve

63 int of a 20% improvement in slope in rate of change of Clinical Dementia Rating Scale sum of boxes ha

64 and high pressure homogenization on quality changes of cloudy apple juice using a multivariate appro

65 a home-made experimental apparatus based on changes of CO2 partial pressures.

66 uity tomato note" with relatively percentage change of compounds; and Fractions 3 and 4 were describe

67 tivity, supported additionally by widespread changes of corresponding metabolites and an increased se

68 More interestingly, a change of coupling between both variables is observed du

69 is crucial to understanding the evolutionary changes of craniofacial biomechanics and the interaction

70 nfirm that geochemistry can be used to track changes of crustal thickness changes in ancient collisio

71 ce measurement (FBRM) to analyze the in-line changes of crystal size distribution during the crystall

72 is suspected that reversible conformational changes of CSP are required for infection of the mammali

73 In multivariate analysis, the dynamic change of CTC with ALK-CNG was the strongest factor asso

74 g cytokine milieu that drives the phenotypic changes of CTCLs.

75 Notably, the incremental change of daily death rate was most prominent during the

76 ts appeared to be correlated with functional changes of DAT.

77 Grade-related changes of DCIS detection are suggestive of distinct dyn

78 parameter, DeltaC1/2%, we compared relative changes of denaturation between peptides.

79 s exposure, nor qualitative and quantitative changes of detected molecules were observed as a functio

80 Purpose To determine the changes of diffusion-tensor imaging (DTI) and tractograp

81 how that Pc detected and localized temporary changes of diffusive behavior both in time and in space.

82 od particularly suitable to study diagenetic changes of dissolved lignin in small-scale laboratory or

83 sented here revealed either no or only minor changes of distance distributions upon Pr-to-Pfr photoco

84 monstrated here in a study of conformational changes of DNA upon binding of the minor groove binder n

85 mphasize the importance of understanding the changes of dominant species for accurately predicting co

86 biotic regimens often include the sequential changing of drugs to limit the development and evolution

87 This study found that changes of dust activity in the U.S. in the recent decad

88 clinical diagnostic dilemma because retinal changes of early stages are often subtle.

89 There was no significant change of either hand grip strength or leg extension pow

90 ld indicate that CD74 NTF-induced structural changes of endosomes are not directly involved in these

91 ltaneous depiction of 3D micro-architectural changes of endplate with aging and interaction with IVD

92 The frequency change of ENSO and WWV were linked to a westward shift o

93 ctional histidine kinases in response to the change of environmental pH.

94 sion modulation ("hierarchical control") and changes of enzyme activities through metabolite-enzyme i

95 ms is regulated through two main mechanisms: changes of enzyme capacities as a consequence of gene ex

96 be insufficient to describe microstructural changes of fat blends with high solid fat content.

97 We report change-of-function SRSF2 mutations.

98 r, shifting AS modes may contribute to rapid changes of gene expression during fruit set.

99 process that results in heritable epigenetic changes of gene regulation and trans-homologue interacti

100 der (PTSD), this study examined longitudinal changes of genome-wide blood DNA methylation profiles in

101 in the news during the 20th century and the change of geographic focus for various concepts.

102 For rat Glut5, a change of glutamine to glutamic acid at codon 166 (p.Q16

103 course of the improvement is mirrored by the change of glutamine/glutamate ratio and if such effects

104 tion measurements were obtained; attenuation change of greater than or equal to 15 HU was considered

105 ficantly differed (P < .05) with a log2 fold change of >/= 1.0 between patient groups were interrogat

106 We sought to test whether the change of gut microbiota with the broad spectrum antibio

107 ther socio-demographic factors influence the changes of health-related quality of life (HRQOL) among

108 Whether there is a change of hepatocellular carcinoma (HCC) incidence in ch

109 Those expression changes of HIF proteins in the process of in-vitro syncy

110 cantly associated with the relative temporal changes of hs-cTnT (p < 0.01, corrected for multiple com

111 eir temporal correlation with the behavioral changes of IJs towards the infected hosts.

112 evaluates the resultant conformation/dynamic change of IL-6R.

113 efit photosynthetic organisms but expression changes of in hospite Symbiodinium in response to acidif

114 tment of insulin secretion to compensate for changes of insulin sensitivity that result from alterati

115 These defects preferentially associate with changes of intragenic H3K4me3 and at lesser extent of H3

116 n to be capable of following the cytoplasmic changes of iron concentration dynamics and we have demon

117 tor fluorophore on a DNA tether are due to a change of its average position in the evanescent field o

118 Long-term changes of its architecture and function on the network

119 e top of a melting wood alloy to examine the changes of its inductance during solidification process.

120 s is attributed to the reversible structural changes of kerogens.

121 ntly, both behavioral defects and structural changes of L5 PNs are prevented by selective pharmacogen

122 ersus 7.4 [15.8], P=0.02) and no significant change of left ventricular ejection fraction in the cell

123 en test for differences in sensitivities, or changes of log lambdas to changes in autocorrelation amo

124 he viscosity of the polymer, the orientation change of LSPR may respond to a wide range of stresses.

125 When sampling coarse-mode aerosol, mass changes of <10 pg can be detected by the sampling drople

126 hanges may render the channel insensitive to changes of luminal Ca(2+) that occur through the cardiac

127 Salinity increase resulted in significant changes of macro and micro-nutrients content (nutritiona

128 ly evaluation of response often results in a change of management in GIST patients harboring the non-

129 myelokathexis, which describes degenerative changes of mature neutrophils and hyperplasia of bone ma

130 nder unit preference leads concurrently to a change of mechanism in which chain extension with fluori

131 rstanding of DNA methylation and the dynamic changes of methylomes during disease onset and progressi

132 ed this noncanonical autophagy, resulting in changes of mitochondrial homeostasis and alterations in

133 y (XANES) suggested a formal oxidation state change of Mn(II)2 in 1 to Mn(II) Mn(III) for 2.

134 of the film to allow for moisture-dependent changes of modulus and swelling degree.

135 In patients with long-term aspirin use, the changes of molecular events in AM but not IM may be an i

136 hat block Qbeta lysis and the conformational changes of MurA that facilitate A2 binding were found to

137 To understand the conformational changes of mushroom PPO, the secondary structural change

138 l biochemical assays for checking phenotypic changes of mutants require a large volume of starting ma

139 her, these results indicate that the rate of change of network-level responses to temperature differe

140 Structural changes of nisin induced by complexation with pectin or

141 NA replication is essential for the rhythmic changes of nucleosome composition at the frq promoter.

142 s chromatin via conformational or positional changes of nucleosomes, thereby altering the access of t

143 Our goal was to quantify the morphological changes of ocular tissues caused by formalin fixation an

144 :4:1+1% citric acid) on the physico-chemical changes of oil used continuously for deep-fat frying of

145 tely switches the reaction course due to the change of one of the reaction centers in the 2-cyanothio

146 mewhat subjective describing and naming main changes of oocytes, have been criticized for confusing a

147 Change of option set size demonstrated choice optimality

148 ving a better understanding of the occurring changes of organic matter during ozonation.

149 metabolite quantities were not the result of changes of other carotenoid concentration, but were more

150 roundings, with concurrently occurring major changes of parasite cell architecture.

151 Diffusometry is sensitive to geometric changes of particles.

152 MT mice.In DYT1 transgenic mice, the inverse changes of PDE10A in striatoentopeduncular and striatopa

153 Similar changes of PDE10A occur in hWT mice, but such changes ar

154 sorbance data with the presence of shifts or changes of peak shapes in spectroscopic analysis.

155 eld dependence of inductance arises from the change of permeability, which correlates with the stress

156 Moreover, the change of PGRN levels led to a cell-type-specific increa

157 inding capacities of albumin by biochemical (changing of pH) and physical (changing of temperature) m

158 ion protocol to simultaneously determine the changes of pHi and [Cl(-)]i in response to hypercapnia a

159 We report that changes of phosphodiesterase-10A (PDE10A) can map widesp

160 m anoxia exposure for 16h on physicochemical changes of 'Phulae' pineapple fruit stored at ambient te

161 A capsize, namely a drastic change of polarization to the perpendicular direction is

162 ates is achieved through the stimuli-induced change of position of the macrocycle on the rotaxane thr

163 values were obtained when pulses with bigger change of potential were used although the best results

164 The change of precipitation decreases with elevation, relief

165 ration and its interaction with the hormonal changes of pregnancy and postpartum.

166 tle is known about the genetic structure and changes of prehistoric populations in different geograph

167 contraction to maintain cardiac output under changes of preload and afterload.

168 e [2Fe-2S] cluster, indicating that a subtle change of protein structure may switch mitoNEET and Mine

169 are drastically altered, resulting in major changes of protein conformation that impacts its biologi

170 in conformations to respond to obstacles and changes of protein density, while maintaining a protecti

171 he monitoring in situ of the microstructural changes of protein gels during simulated gastric digesti

172 esentation as it neglects the conformational changes of proteins which may lead to different interact

173 dohydrolase induced hemodynamic and vascular changes of pulmonary hypertension in rats (n=8) and elev

174 Incremental changes of RA gradient slopes establish a continuum of a

175 er was found to be associated with increased change of refractive error during follow-up years.

176 sm was found to be associated with increased change of refractive error during follow-up years.

177 GaSb sample and explained the discontinuous change of resistivity after metallization.

178 her dispersal ability influences the rate of change of SADs as a function of sample size.

179 However, it implies an artificial change of sample composition with a risk of losing impor

180 The primary endpoint was the change of serum bilirubin, creatinine and serum BUN leve

181 ive experimental insight into the structural changes of silicate glasses as analogue materials for si

182 ore by ions allows monitoring conformational changes of single and native substrate-binding domains (

183 We measured either volume changes of single hypocotyl protoplasts or hypocotyl gro

184 This work shows that morphological changes of solid-state syndiotactic polymers, driven by

185 f nitrogen and phosphorus, and concentration changes of soluble ions.

186 r other tools that measure the concentration change of solutions.

187 y with lipid enrichment, but also with zonal changes of specific lipids and their associated metaboli

188 inference is associated with the structural changes of specific social brain regions in late adolesc

189 versal of ferroelectric polarization with no change of spin-helicity, and present a phenomenological

190 rein, we report light-induced conformational changes of SPs based on the 1D exotic stacking of hydrog

191 sts that Sec3 binding induces conformational changes of Sso2 that are crucial for the relief of its a

192 This study investigated specific changes of suicidal ideation in functional connectivity

193 60 [3.6] versus 5.01 [4.3], P=0.32; absolute changes of summed difference score: -1.38 [5.2] versus -

194 olled, smart films that undergo simultaneous changes of surface color and morphology upon infrared (I

195 y biochemical (changing of pH) and physical (changing of temperature) modulation of the dialysate.

196 Moreover, the colorimetric change of the assemblies could be well-retained after th

197 we model the effect of the mutation and the change of the association strength, which could explain

198 ent definitions used to identify progressive change of the average peripapillary retinal nerve fiber

199 ression of the active site, a conformational change of the carboxylate side chain metal ligand to all

200 tion suggest that reversible hydration-level change of the cavity can indeed be a key factor that reg

201 CDW) phase and associated with a concomitant change of the CCDW order parameter in the interfacial re

202 The main endpoint was the change of the central foveal thickness (CFT) obtained by

203 al data, an unrealistically large structural change of the channel is required.

204 The rate of change of the clinical and cognitive scores varied depen

205 in which TRIP8b inhibits the conformational change of the CNBD associated with cAMP regulation and a

206 cal Mean Field Theory, which can predict the change of the crystal structure across the MIT at finite

207 The semiquantitative method, eg, the change of the difference of maximum standardized uptake

208 The change of the DRIL extent following the first 3 monthly

209 es of mushroom PPO, the secondary structural change of the enzyme during thermosonication treatment a

210 at D-serine rapidly induces a conformational change of the GluN1 subunit intracellular C-terminus dom

211 The observed resistance change of the graphene temperature sensors are explained

212 a dynamical phase transition after a sudden change of the Hamiltonian, in a regime in which conventi

213 ct the onset of seizures) and with the power change of the high-gamma rhythm.

214 The change of the inductive voltage near the destructive int

215 gation kinetics suggests that conformational change of the light chain is rate-limiting for these pro

216 se, the mean +/- SD post-arrival incremental change of the ln-transformed troponin-T at 72 h was 0.79

217 cently, an alternative pathway involving the change of the magnetic state (ferromagnet to antiferroma

218 tration, an increase of product price, and a change of the market share of high-sugar, mid-sugar, and

219 a point of the Brillouin zone resulting in a change of the nature of the fundamental band gap from in

220 stigating how thermal variation results in a change of the operation state of a micrometer sized elec

221 The color change of the optode is recorded via an iPhone camera an

222 of the inductive voltage, as well as in the change of the output phase.

223 ief of the contact quenching, resulting in a change of the PA signal ratio at 780/725 nm.

224 ely fast), and the subsequent conformational change of the protein (charge-independent, relatively sl

225 usted for age and sex, and the relative area change of the pulmonary artery.

226 In some cases, the change of the ratio of amine to alcohol improves the con

227 the ligand associated with a conformational change of the receptor.

228 ated across participants with the respective change of the RPE signal in the nucleus accumbens.

229 This strategy allows a remarkable change of the secondary structure via a small modificati

230 To characterize the change of the shape of the SADs we use the moments of th

231 A drastic change of the shell morphology was observed by changing

232 We suggest that the conformational change of the syntaxin-1 linker region induced by Munc13

233 c quantum criticality is avoided either by a change of the transition order, becoming of the first or

234 (95% CI 0.16-0.66) reduction in the rate of change of the Unified Huntington's Disease Rating Scale

235 inetics and conformational and morphological changes of the Abeta peptide are poorly defined.

236 on temperature could be shifted by adiabatic changes of the ambient temperature, and the magnitude of

237 This identifies a novel mechanism by which changes of the amplitude of the systolic Ca transient co

238 ld, n = 246), we characterized developmental changes of the amygdala-vmPFC subregion functional and s

239 ssDNA aptamers and subsequent conformational changes of the aptamer probe which affect the electron t

240 es not inevitably lead to the conformational changes of the beta2 subunit.

241 ents an endogenous mechanism that translates changes of the brain state into a shift of the regime of

242 rate specificity by concerted conformational changes of the central beta hairpin and the C-terminal e

243 To identify biomechanical and topographic changes of the cornea during pregnancy and the postpartu

244 the profile of carotenoids with fundamental changes of the deposition state of carotenoids in goji b

245 t interpretation of artifacts resulting from changes of the detection geometry in the investigation o

246 Here we characterize spatiotemporal changes of the elastic stiffness of the injured rat neoc

247 er, few studies have investigated the global changes of the entire organism with respect to antibioti

248 o and the product type affected, significant changes of the flows occur over time, driven by the grow

249 Changes of the fluorescence indexes related to tyrosine-

250 Changes of the fluorescence indexes that correspond to a

251 This postural evolution included anatomical changes of the foot and ankle, altering the moment arms

252 erol metabolism by the host for diet-induced changes of the gut microbiota and energy metabolism.

253 0, and protein uS2, involving conformational changes of the head as well as surface regions that coul

254 ith time-dependent mechanical and histologic changes of the healing tendon in a transected rabbit mod

255 ed comprehensive details of 3D morphological changes of the IVD and canal network in the endplate and

256 ge-clamp fluorometry to track conformational changes of the KCNQ3 voltage-sensing domains (VSDs) in r

257 t solvent-induced spectral and photophysical changes of the labels, leads to deviations of up to 4 A

258 earning techniques to convert the expression changes of the landmark genes into a perturbation barcod

259 e interphase cannot match the dynamic volume changes of the Li anode, resulting in side reactions, de

260 ult in changes in plasma membrane targeting, changes of the localization pattern, and of the diffusio

261 describe objectively the possible structural changes of the macula and optic nerve head in the free e

262 We have assessed the structural changes of the Nav voltage sensor domain using lanthanid

263 and will pave the way for observing dynamic changes of the objects such as deformation or change in

264 etween functional vision loss and structural changes of the optic nerve head and retinal ganglion cel

265 t with reduced speed and transient curvature changes of the parasite.

266 bility of EEM-PARAFAC to monitor the dynamic changes of the primary pollutant sources.

267 adsorption and could promote conformational changes of the proteins and subsequent abnormal biologic

268 tions resulting in structural and functional changes of the proteins involved.

269 To quantify the microstructural changes of the retina in CZS and compare these changes w

270 iffness of the DNA layer is measured through changes of the sensor resonance frequency upon hybridiza

271 he large and highly nonlinear conformational changes of the sheath whose elastic energy drives the in

272 fusion and deformation-related morphological changes of the sintering particles.

273 enerally achieved by head movements or shape changes of the sound-emitting mouth or nose.

274 Genome editing is expected to result in changes of the spectrum of model organisms, a reason to

275 Expression changes of the TGF-beta1 active dimer and ENG were analy

276 In model neurons, such changes of the weight dependence of heterosynaptic plast

277 y spectrometers (FAIMS) separate them by the change of their ion mobility at high fields.

278 challenging because it requires a continuous change of thermal properties in materials, for one speci

279 ations without greatly affecting the rate of change of these representations.

280 r long-term changes compared with short-term changes of these outcomes.

281 ke of AM did not significantly influence the changes of these parameters.

282 Compositional and functional changes of this microbial ecosystem are correlated with

283 d delta (15)N we investigated potential diet changes of three commercially exploited species across t

284 ystolic Ca transient, such that there was no change of time-averaged [Ca(2+) ]i .

285 is a powerful tool to study the coordinative change of time-course data.

286 this end, we documented whole transcriptome changes of tomato elicited by the application of the mos

287 te matter signal abnormalities can mimic the changes of toxic leukoencephalopathy.

288 ure by histone modifications and recruitment changes of transcriptional factor complex in the ERalpha

289 The conformational change of triazole polypeptides in response to the donor

290 contributor to the intermodel spread in the changes of tropical-mean outgoing longwave radiation (OL

291 The distinct structural changes of troponin C in the thin filaments and myosin r

292 depletion evokes a C-terminal conformational change of TRPC5 proteins leading to dynamic dissociation

293 s per year (95% CI 0.06-0.18) in the rate of change of UHDRS Total Functional Capacity score.

294 different time scale for the UFG cores with changes of up to 80 years.

295 n accounted for 54% of the variation in fold changes of urinary PAH metabolites (p < 0.002).

296 ene insertion was associated with structural changes of variable complexity, illustrating the importa

297 ansmission, motor impairment, and measurable change of VMAT2 in the absence of cell loss.

298 This study first reports the dynamic changes of volatiles and phenols that occur during skin

299 ve mass spectrometry to compare the proteome changes of wild type UA159 and lrgAB mutant strains in r

300 Fluoroscopy time, PCI procedure complexity, change of x-ray equipment, and other patient- and proced