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1 th the human STAGA (SPT3-TAF-GCN5 acetylase) coactivator complex.
2 transcription factor and its cognate, OCA-S coactivator complex.
3 RIP150, a subunit of the multimeric Mediator coactivator complex.
4 nguishable from our previously isolated CRSP coactivator complex.
5 y linked to selective recruitment of a Tip60 coactivator complex.
6 t also with the H3K4 methyltransferase KMT2D coactivator complex.
7 as part of the SAGA (SPT-ADA-GCN5 acetylase) coactivator complex.
8 a human thyroid hormone receptor-associated coactivator complex.
9 , GRIP-1, and DRIP205, a subunit of the DRIP coactivator complex.
10 ctivators and autoregulation by the receptor-coactivator complex.
11 ys a central role in creating a multisubunit coactivator complex.
12 an H3K27me3 demethylase Jmjd3/Kdm6b-centred coactivator complex.
13 colon cancer cells by recruiting EZH2 to the coactivator complex.
14 n the assembly of the active ligand.receptor.coactivator complex.
15 ates hormone signaling by disassembly of the coactivator complex.
16 iates transcriptional activation by the p160 coactivator complex.
17 ximal promoter, and (d) assembles a distinct coactivator complex.
18 ion promotes dissociation of the SRC-3/CARM1 coactivator complex.
19 for disassembly of the SRC-3 transcriptional coactivator complex.
20 ionally depends on the multiprotein Mediator coactivator complex.
21 ix1/Eya bipartite transcription (DNA binding/coactivator) complex.
22 one in deciphering the mechanism of multiple coactivator complexes.
23 into the interaction of diverse proteins in coactivator complexes.
24 nduce transcription through association with coactivator complexes.
25 stimulating the exchange of corepressor for coactivator complexes.
26 pecific role in substrate recognition by APC-coactivator complexes.
27 the relative affinities for corepressor and coactivator complexes.
28 tion is not driven by a random mixture of ER-coactivator complexes.
29 cruitment of one or more recently identified coactivator complexes.
30 tial recruitment of SRC-1 and PBP-containing coactivator complexes.
31 hanisms, and link the complex to other human coactivator complexes.
32 ed disruption of activator interactions with coactivator complexes.
33 e component of COMPASS-like nuclear receptor coactivator complexes.
34 tress-specific regulation of transcriptional coactivator complexes.
35 mediate assembly of these two very different coactivator complexes.
36 vated Stat3-mediated recruitment of distinct coactivator complexes.
37 ch was reported to be a component of the SRC.coactivator complexes.
40 )-associated transcriptional corepressor and coactivator complexes allow for the precise regulation o
41 receptor-associated proteins) transcription coactivator complex (also known as Mediator) was first i
42 inctive interface for a transcription factor-coactivator complex and demonstrates a functional role f
43 o alter the conformation and activity of the coactivator complex and regulate estrogen receptor-media
44 ssion and may be components of both a common coactivator complex and separate complexes with distinct
45 recruitment of the Mediator transcriptional coactivator complex and transcriptional activation, but
46 tes with components of the Mediator and p160 coactivator complexes and is recruited to endogenous NR
47 sociate the repressing complexes and recruit coactivator complexes and RNA polymerase II, thereby ind
48 steroid receptors elicit precise assembly of coactivator complexes and the way the steroid activation
49 r-specific and ligand-specific assembly of a coactivator complex, and that these recognition motifs u
50 tion through action on the MTA1/STAT3/Pol II coactivator complex, and, in turn, on the expression and
51 s a component of two different transcription coactivator complexes, and recent work indicates that di
52 r phosphorylation has been shown to regulate coactivator complex assembly, but the mechanisms by whic
53 s represent unique mechanisms for regulating coactivator complex assembly, conformation, and function
54 irm that a nuclear receptor employs distinct coactivator complexes at different target genes, and pro
56 ed coactivator complex with the PBP-anchored coactivator complex but differentially modulates coactiv
57 or is a conserved, essential transcriptional coactivator complex, but its in vivo functions have rema
59 we find that the stability of multi-subunit coactivator complexes can be compromised by loss of a si
62 ent of histone acetyl transferase containing coactivator complexes conserved from yeast to human.
63 two activators differentially recruited the coactivator complexes, consistent with specific activato
64 ne-occupied PR forms a multisubunit receptor-coactivator complex containing two previously described
65 activator complex with other coactivators or coactivator complexes containing actin or actin-like pro
68 ferences in configuration and content of the coactivator complex dictate requirements for specific ac
69 histone H3 and also dictates the subsequent coactivator complex disassembly by methylation of the st
70 e previously identified a novel multisubunit coactivator complex, DRIP (VDR-interacting proteins), re
71 ecently observed that VDR binds to two major coactivator complexes, DRIP (VDR-interacting protein) an
72 insights into how the multisubunit Mediator coactivator complex dynamically links enhancer-bound act
73 al, ligand-dependent recruitment of multiple coactivator complexes (e.g., SRC complexes and Mediator)
76 l as well as participating in formation of a coactivator complex essential for transactivation of MT-
81 The Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator complex hyperacetylates histone tails in viv
84 tact with DRIP150 and implicate the Mediator coactivator complex in IFN-activated gene regulation.
85 00/CBP and SRC proteins are part of the same coactivator complex in vivo during post-embryonic develo
88 omponent of the SAGA and ADA transcriptional coactivator complexes in budding yeast, suggests an imme
89 d "molecular adaptor" actions of corepressor/coactivator complexes in integrating signal-dependent pr
91 ion protein to components of three different coactivator complexes in Saccharomyces cerevisiae cell e
92 e evolutionarily conserved hADA3 in multiple coactivator complexes, inactivation of its function may
95 the cell uses several classes of regulatory coactivator complexes including two central players, TFI
96 hree components of the p160 nuclear receptor coactivator complex, including CARM1, p300/CBP, and GRIP
97 ctionally require distinct components of the coactivator complex, including CREB-binding protein (CBP
98 ion to Hog1, specific components of the SAGA coactivator complex, including Spt20 and Sgf73, are also
99 sociated with enhanced promoter occupancy of coactivator complexes, including SAGA, Mediator, chromat
100 F9-ADA-GCN5 acetyltransferase) transcription coactivator complex, interacts directly with the GCN5 hi
101 ADA2 or GCN5, encoding components of the ADA coactivator complex involved in histone acetylation, sev
102 and PBP (PPARgamma-binding protein)-anchored coactivator complexes involved in the transcriptional ac
103 nd PBP (PPAR gamma-binding protein)-anchored coactivator complexes involved in the transcriptional ac
108 by the Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator complex is regulated by a recently discovere
109 Thus, we propose that a CBP/p300-containing coactivator complex is the E1A-sensitive factor importan
112 rginine methyltransferase activity to the ER-coactivator complex, it also alters the structural organ
113 es have implicated the multisubunit Mediator coactivator complex (Med) as a critical component of the
114 lase PCAF has been suggested to be part of a coactivator complex mediating transcriptional activation
116 tion of a number of critical subunits of the coactivator complex Mediator alters only a few MAPK-resp
117 d Tra1, which are subunits of four conserved coactivator complexes, Mediator, SAGA, TFIID, and NuA4.
118 D), belong to two homologous transcriptional coactivator complexes, named MLL3 and MLL4 complexes, re
119 recruited a limited set of chromatin-related coactivator complexes, namely the chromatin remodeler Sw
122 nuclear receptors determines the assembly of coactivator complexes on target promoters to mediate spe
123 irects the recruitment of mutually exclusive coactivator complexes on the p53 response elements in th
124 recruiting transcriptional corepressors and coactivator complexes onto neuroectoderm, mesoderm, and
125 ucers, which act in vivo either as part of a coactivator complex or downstream of a coactivator compl
126 n and stability of transcriptional activator-coactivator complexes, perhaps in part due to the often
129 d by human mediator, another transcriptional coactivator complex potentially implicated in activator
130 ubunit of the plant Mediator transcriptional coactivator complex regulates cold-responsive gene expre
131 tor (ARC), a family of large transcriptional coactivator complexes related to the yeast Mediator, was
132 tigate the mechanisms by which transcription coactivator complexes relieve chromatin repression in vi
133 cognition motifs underlie the recruitment of coactivator complexes required for nuclear receptor func
134 venting the assembly of CBP-nuclear receptor coactivator complexes, revealing differences in required
137 enzyme is found in two functionally distinct coactivator complexes, SAGA (Spt Ada Gcn5 acetyltransfer
139 n assay to discover a multisubunit stem cell coactivator complex (SCC) that is selectively required f
142 itamin D receptor interacting protein (DRIP) coactivator complex shares components with the RNA polym
143 hich encodes a polypeptide unique to the ADA coactivator complex, stimulates Gal4-final sigma(54)-med
144 cription factors make weak interactions with coactivator complexes, such as Mediator, to stimulate tr
145 (54) is TATA-dependent and requires the SAGA coactivator complex, suggesting that Gal4-final sigma(54
146 nd the role of core promoter recognition and coactivator complex switching in cellular differentiatio
149 ediator complex is a central transcriptional coactivator complex that acts as a bridge between transc
152 nd mediates the assembly of a Cti6-Cyc8-Tup1 coactivator complex that functions to recruit the SAGA c
153 accharomyces cerevisiae is a multifunctional coactivator complex that has been shown to regulate tran
154 ort we demonstrate that NF-kappaB recruits a coactivator complex that has striking similarities to th
155 elease the corepressor complex and recruit a coactivator complex that includes multiple histone acety
156 ity chromatography, we have isolated a human coactivator complex that interacts directly with the C-t
158 of posttranscriptional modification of a NR-coactivator complex that is important for NR signaling.
159 r activators (p53 and VP16) through a common coactivator complex that is likely to target RNA polymer
160 y of Gcn4p to interact with several distinct coactivator complexes that are physically and geneticall
161 our results establish hAda3, a component of coactivator complexes that include histone acetyltransfe
162 ependent recruitment of a series of specific coactivator complexes that prove necessary for Cyclin D2
163 other component of the p160 nuclear receptor coactivator complex, the coiled-coil coactivator (CoCoA)
165 nscription is driven by dynamic multiprotein coactivator complexes, the composition of which is thoug
166 scription activators contact the same set of coactivator complexes, the mechanism and specificity of
167 physically interact to stabilize the ERalpha-coactivator complex, thereby permitting other signal tra
170 mediation of transcription factor binding to coactivator complexes through multiple interactions.
171 f a receptor kinase recruits a transcription coactivator complex to a specific chromosomal locus to m
172 oid response, by recruiting the p300/CBP/SRC coactivator complex to an FKH factor site in the IGFBP-1
173 t-Ada-Gcn5-acetyltransferase transcriptional coactivator complex to catalyze histone acetylation at t
174 ural information on the full-length receptor-coactivator complex to complement preexisting and someti
175 of a coactivator complex or downstream of a coactivator complex to modulate transcriptional activity
176 the ligand-dependent recruitment of the DRIP coactivator complex to VDR and to the ability of the rec
177 regulates the assembly and activity of bHLH-coactivator complexes to promote neuronal differentiatio
180 Ada3p, suggesting that recruitment of these coactivator complexes to the promoter is a cardinal func
181 cription through the recruitment of multiple coactivator complexes to the promoter regions of target
182 ctivate transcription by recruiting multiple coactivator complexes to the promoters of target genes.
183 merase II transcription machinery, conserved coactivator complexes, transcription activation domains,
186 n depleted extracts showed that the Mediator coactivator complex, which controls PIC assembly, is als
188 receptor-associated protein (TRAP)/Mediator coactivator complex, which interacts with ERalpha and ER
189 an important component of the plant mediator coactivator complex, which links promoter-bound transcri
190 ind general transcription factors and larger coactivator complexes, which position RNA polymerase II
191 -dependent interactions of this multisubunit coactivator complex with nuclear receptors through their
192 Fli-I may facilitate interaction of the p160 coactivator complex with other coactivators or coactivat
193 eraction of the MTA1.RNA polymerase II.c-Jun coactivator complex with the HMMR promoter to stimulates
194 gest that PIMT bridges the CBP/p300-anchored coactivator complex with the PBP-anchored coactivator co
195 g stimulates association of the beta-catenin coactivator complex with two Wnt responsive enhancers (W
196 icoid receptor-interacting protein 1 (GRIP1) coactivator complexed with the ligands OBCP-3M, OBCP-2M,
198 copy to determine atomic structures of APC/C-coactivator complexes with either Emi1 or a UbcH10-ubiqu
200 stic formation of transient nuclear receptor-coactivator complexes with its molecular dynamics and ce
201 LL motif and disrupts the association of HAT coactivator complexes with promoter-bound estrogen recep
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