ライフサイエンスコーパス: coevolve

1 ion under conditions with which they did not coevolve.

2 d their opinions and the network connections coevolve.

3 lly dependent on each other that they had to coevolve.

4 That is, black holes and bulges coevolve.

5 ap initially, but gets costly when predators coevolve.

6 titutions at neighboring sites, residues can coevolve.

7 environment-dependent payoffs and strategies coevolve.

8 nication signals and perceptual systems have coevolved.

9 B and LanC enzymes appear to not always have coevolved.

10 he virus and the host's immune response have coevolved.

11 A56, indicating that these proteins may have coevolved.

12 es of terrestrial vertebrates with whom they coevolved.

13 hose motions are thermally coupled have also coevolved.

14 obe association that is both mutualistic and coevolved.

15 and suggests the N1 TMD and head domain have coevolved.

16 gumes and soil bacteria called rhizobia have coevolved a facultative nitrogen-fixing symbiosis.

17 Thus, yeast and Ty1 have coevolved a form of copy number control that is benefici

18 In the transmembrane region, sites that coevolved according to polarity and hydrophobicity rathe

19 nd female reproductive tract morphology have coevolved across species, postcopulatory sexual selectio

20 Creation of optimal coevolving active-site networks is therefore an importan

21 Predators coevolved alongside prey bacteria and so encode diverse

22 Analyses of coevolved amino acid positions suggest that structurally

23 natural proteins in which sparse networks of coevolving amino acids (termed sectors) comprise the ess

24 subset of the H7N9 HA sequences demarcating coevolving amino acids appears to be in the antigenic re

25 ypically coevolve, and the identification of coevolving amino acids can pinpoint residues required fo

26 ent a hypothesis that a network of conserved coevolving amino acids in inteins mediates these long-ra

27 ns in an evolutionarily conserved network of coevolving amino acids in the PDZ family (the sector) th

28 lyses of protein families reveal networks of coevolving amino acids that functionally link distantly

29 sparse networks of physically contiguous and coevolving amino acids underlie basic aspects of structu

30 The animal and bacterial kingdoms have coevolved and coadapted in response to environmental sel

31 Genes encode components of coevolved and interconnected networks.

32 mbers with a XX domain, the two modules have coevolved and that the length of a loop within the XX do

33 is, we identify and characterize clusters of coevolving and functionally linked residues within UbcH5

34 Interacting proteins typically coevolve, and the identification of coevolving amino aci

35 under which sequence, structure and function coevolve are not fully understood.

36 ts that the structural components of meiosis coevolve as adaptive modules that may change in primary

37 suggest that KIR and MHC class I genes have coevolved as an interacting system.

38 , a symbiotic host-microbial interaction has coevolved as bacteria make essential contributions to hu

39 sal ganglia and that the PPN appears to have coevolved as part of a mechanism for action selection co

40 productive mode and epistasis are allowed to coevolve, asexual reproduction outcompetes sexual reprod

41 dicate that the bacteria have an ancient and coevolved association with the ants, their fungal cultiv

42 Most studies involve non-coevolved associations, indicating that fitness alignmen

43 ingly diverse and specifically fitted set of coevolving attack and defense structures.

44 Animals are colonized by coevolved bacterial communities, which contribute to the

45 Our study shows how competition between coevolving bacterial strains can generate antibiotic res

46 thesize that larger brains and smaller teeth coevolved because behavioral changes associated with inc

47 gical function or if their expression levels coevolve between species.

48 , suggesting that reproductive molecules may coevolve between the sexes.

49 inding surface, indicative of a coordinated, coevolving binding surface.

50 ized that interacting residues might tend to coevolve, but it is not known whether such coevolution i

51 ls unanticipated evolutionary modularity and coevolving components.

52 that the Cbeta FG loop and CD3gamma subunit coevolved, consistent with this notion.

53 ons to incorporate costs and benefits of two coevolving costly traits: cooperative and local cohesive

54 , quantified by methane production, requires coevolved cross-feeding interactions between species [12

55 utter ants following full domestication of a coevolving cultivar 30-35 Mya after the first attine ant

56 Flowering plants might have coevolved double fertilization and imprinting to prevent

57 In many cases, host and pathogen have coevolved, each acquiring sophisticated ways of inducing

58 Together, these findings imply that coevolved ecological interactions in species-rich system

59 any invasive species are able to escape from coevolved enemies and thus enjoy a competitive advantage

60 scape can decouple and protect asexuals from coevolving enemies.

61 genomic heterogeneity within the coexisting, coevolving fer1(env) population.

62 ics, is but one of the challenges facing the coevolving fields of computational, evolutionary, and th

63 tural environment that is enriched by highly coevolving flexible residues.

64 Using replicate seminatural populations of a coevolving freshwater invertebrate-parasite system (host

65 However, because the coevolving genes are not necessarily in physical linkage

66 Distinct combinations of alleles in coevolving genes interact differently, conferring varyin

67 y among these is the disruption of favorable coevolved genetic interactions that can occur following

68 in Gag is as conserved as other collectively coevolving groups of sites in Gag.

69 hogens should be considered as two extensive coevolving groups rather than as individual host species

70 portunity to quantify selective impacts of a coevolved herbivore and calibrate rates of phytochemical

71 We have coevolved high activity and hyperstability in subtilisin

72 ll intestinal immune maturation depends on a coevolved host-specific microbiota.

73 its of resistance and virulence in a tightly coevolving host-pathogen pair.

74 persistence is due to robust, and sometimes coevolved, host-microbe and microbe-microbe interactions

75 tent with EAB being a secondary colonizer of coevolved hosts, drought stress decreased the resistance

76 lasmids evolved in H2 improved only in their coevolved hosts, not in the ancestral host.

77 odulated disease risk, and the disruption of coevolved human and H. pylori genomes can explain the hi

78 morphic, physically unlinked, and putatively coevolving human gamete-recognition genes ZP3 and ZP3R.

79 ounding microenvironment are hypothesized to coevolve in a manner that promotes tumor growth, invasiv

80 Thus, the splicing elements defining exons coevolve in a way that preserves overall exon strength,

81 ation are functionally related and do indeed coevolve in predictable ways.

82 Residue pairs that directly coevolve in protein families are generally close in prot

83 nteract in gene-for-gene (GFG) relationships coevolve in the familiar boom-and-bust cycle, in which r

84 ction regulation, and population frequencies coevolve in the simple case of two cell types producing

85 ntized native structure and stepwise folding coevolved in ancient repeat proteins and were retained a

86 using and +1 nucleosome positioning may have coevolved in animals.

87 thesis are both derived characters that have coevolved in anophelines, driving the adaptation of a fe

88 DNA binding preferences of nucleosomes have coevolved in different species.

89 vered that PCNA-partner interactions tightly coevolved in fungal species, leading to specific modes o

90 shows that CD4 T cell memory and lymph nodes coevolved in placental mammals.

91 to unique host and pathogen genes that have coevolved in response to host immunity.

92 w is that the ancestral alphaherpesvirus VZV coevolved in simians, apes, and hominins in Africa.

93 trans-regulatory elements within species had coevolved in such a way that changes in cis-regulatory e

94 lent health care-associated MRSA strains may coevolve innate host defense peptide and antibiotic resi

95 Coevolving interacting genes undergo complementary mutat

96 Using a coevolved interaction between a group of chrysomelid bee

97 These findings suggest that there is a coevolved interaction between the juxtatransmembrane ami

98 Here, I argue that the changing balance of coevolved interactions between hosts and their antagonis

99 ommunity might be co-selected as a result of coevolved interactions.

100 how allosteric activators and their targets coevolve is poorly understood.

101 on with the substrate are compensated by the coevolving L449F and S451N cleavage site mutations.

102 aptured through small modifications of these coevolving learning and data-acquisition mechanisms, who

103 Plants and their pathogens coevolve locally.

104 The model employs relatively simple coevolving mechanisms of learning and data acquisition t

105 alytic core C-terminal cysteine pairs of its coevolved MerA and by glutathione (GSH), the major compe

106 d by our increasing awareness of the role of coevolved microbial symbionts in health and disease.

107 ector targets in plants, support a model for coevolving molecular dialogs between effector repertoire

108 Our computational model simulates coevolving multitype virus and antibody populations.

109 egion and part of the capsid region from the coevolved mutant gag gene were sufficient to achieve ful

110 tely rescued by coexpressing the full-length coevolved mutant gag gene.

111 strate interactions reveal that compensatory coevolved mutations in the substrate do not restore inte

112 an additional constraint in the selection of coevolved mutations.

113 HIV-1 protease with p1-p6 substrates bearing coevolved mutations.

114 curring heterotrophic bacterium SAR11 form a coevolved mutualism that maximizes their collective meta

115 es a potent immunomodulatory function in the coevolved network of host-parasite relationships during

116 t noncatalytic sites that restore an optimal coevolving network and vice versa.

117 00-fold range by mutation of residues in the coevolving network.

118 een rhizobia and legume plants is a model of coevolved nutritional complementation.

119 ERalpha- and RAR-binding sites appear to be coevolved on a large scale throughout the human genome,

120 Therefore, black holes coevolve only with bulges.

121 ection for adjacent residues among predicted coevolving pairs in the surface region indicates that th

122 onformations and to the cooperativity of the coevolving pairs.

123 lity is rapidly extinguished by relentlessly coevolving parasites and pathogens.

124 Under the "Red Queen" hypothesis, coevolving parasites reduce the reproductive advantage o

125 he existence of hot spots and cold spots for coevolving parasites.

126 uppression methods, including the release of coevolved parasitoid species targeting invasives, have b

127 eriod prepares the animal to engage with the coevolved partner(s) with fidelity following birth or ha

128 a high-affinity, functional complex with its coevolved partner, TgRON2L1.

129 e antibiotics that specifically suppress the coevolving pathogen Escovopsis, which infects the ants'

130 s, consistent with the Red Queen hypothesis, coevolving pathogens can select for biparental sex.

131 ueen hypothesis proposes that selection from coevolving pathogens facilitates the persistence of outc

132 This naturally coevolving pathosystem contains an amazing level of gene

133 was correlated with the range of hosts that coevolved phage were able to infect.

134 which is consistent with the fact that both coevolved phenotypes resemble strains commonly found in

135 ,7), altered selective regimes could disrupt coevolved plant-pollinator interactions, weakening an im

136 ults demonstrate a significant potential for coevolved plant-pollinator relationships to be disrupted

137 is demonstrates that the highly variable but coevolving polar residues at the interface of dimeric bu

138 nism for this lectin complex formation where coevolving polar residues of high closeness are responsi

139 stic interactions between mutations from the coevolved populations.

140 ng selection dynamic; FSD) in experimentally coevolving populations of bacteria and viruses.

141 ely to be due to generalized transduction by coevolving populations of phages, which could efficientl

142 ion analysis and experimentation to identify coevolving positions and found that residues 35 and 39 a

143 Furthermore, in contrast to most coevolving protein residues that contribute to the same

144 ghtly coupled interaction involving a single coevolved R gene and effector pair.

145 h different progression driver mutations may coevolve rather than compete during clonal evolution.

146 mographic shifts have profoundly altered the coevolved relationship between host and microbiota, depl

147 nhabit mammalian body surfaces have a highly coevolved relationship with the immune system.

148 ies, their operations, and their dynamically coevolving relationships with the habitats they occupy w

149 acid (rTCA) cycle and clay mineral catalysts coevolved remains a mystery in the puzzle to understand

150 system-specific mathematical model and then coevolved replicate populations of the bacterium Pseudom

151 otein families, we find that 25% of directly coevolving residue pairs are separated by more than 5 A

152 The majority (91%) of directly coevolving residue pairs in the 5-15 A range are found t

153 Overall, the results suggest that directly coevolving residue pairs not in repeat proteins are spat

154 he exceptions to this general trend-directly coevolving residue pairs that are distant in protein str

155 The occurrence of coevolving residues at the DnaJ recognition region paral

156 Identification of coevolving residues further advances the protein structu

157 an phylogenetic approach to the detection of coevolving residues in protein families.

158 results, we demonstrate that a subset of the coevolving residues is sufficient, when mutated, to comp

159 ignments that was used to identify groups of coevolving residues termed "sectors".

160 brane region, although the distances between coevolving residues were greater.

161 In this paper, we identify groups of coevolving residues within HCV nonstructural protein 3 (

162 valuate how well methods developed to detect coevolving residues within proteins can be adapted for c

163 Here, using computational methods to predict coevolving residues, we identify a network of positions

164 to co-chaperone recognition and activity via coevolving residues, whereas interdomain allostery, crit

165 s to overcome the disruption of this tightly coevolving ribonucleoprotein.

166 In this work, the largest coevolving RNA/protein signatures in the bacterial 30S r

167 ssive infection, correcting for HLA bias and coevolving secondary mutations, a significant difference

168 innate immune and stress responses, and as a coevolved sensory stimulus that modulates neuronal signa

169 hat the interplay between the disruptions of coevolved sets of loci by outcrossing, the efficient pur

170 A bioinformatics study identified a coevolving signal-accepting network of 10 amino acids in

171 s diversifies into defence specialists, when coevolved simultaneously with a virus and a predatory pr

172 ic tools that provides methods for detecting coevolving sites from a multiple alignment of homologous

173 MM method can successfully detect nearly all coevolving sites when the model has been correctly speci

174 ve process where EBV and its human host have coevolved so as to minimize the virus's potential to con

175 Thus, the repressor-operator interface has coevolved so as to retain the interaction while altering

176 their host galaxies are generally thought to coevolve, so that the SMBH achieves up to about 0.2 to 0

177 er suppression documented here suggests that coevolving social strategies within natural populations

178 variable revealed that reassociation with a coevolved specialist in a nonindigenous area profoundly

179 body of work has explored what happens when coevolved species shift out of sync, but virtually no st

180 Reciprocal selective effects between coevolving species are often influenced by interactions

181 ukaryotic protein kinases (EPKs) feature two coevolved structural segments, the Activation segment, w

182 Many marine organisms have coevolved symbiotic relationships with nitrogen-fixing b

183 n as the kinetically favored pathway in this coevolved system.

184 orical host, further increasing risk in less coevolved systems.

185 Conversely, in Australia, where coevolved taxa are absent, R. marina largely fills its f

186 w intimately host pathogen interactions have coevolved through similar and divergent evolutionary str

187 drug resistance and immune escape mechanisms coevolve, thus increasing the likelihood of treatment fa

188 al or learned, because genes and culture may coevolve to determine variation in dietary habits.

189 Genes for receptors and ligands must coevolve to maintain coordinated gene expression and bin

190 sts that metazoan mucosal surfaces and phage coevolve to maintain phage adherence.

191 ions in only one env subunit, gp120 and gp41 coevolve to maximize viral fitness under sequential drug

192 We conclude that VAB and SN enhancement coevolved to compensate for loss of vision and to help b

193 hese two receptor systems suggests that they coevolved to constitute a highly sensitive and efficient

194 Among a number of mechanisms that coevolved to control adaptive immunity is anergy, the fu

195 falciparum, and the human immune system have coevolved to ensure that the parasite is not eliminated

196 2 and the composition of amniotic fluid have coevolved to ensure the formation of a functional barrie

197 Their energy landscapes are similar and have coevolved to facilitate competitive binding to the IL-1

198 suggests that both the protein and RNAs have coevolved to interact with each other such that a single

199 rt B domains and mitochondrial adaptors have coevolved to meet the unique requirements for mitochondr

200 that these functionally interacting proteins coevolved to optimize the gastric colonization capacity

201 tigate how certain domains of E1 and E2 have coevolved to optimize their interactions to promote effi

202 nervous and immune systems have, therefore, coevolved to permit effective immune surveillance while

203 mammals suggests that these paralogous genes coevolved to play cooperative roles during spermiogenesi

204 ed in a cultural niche and teaching-learning coevolved to transmit culture.

205 architecture of the SPP1 infectious particle coevolved toward high robustness.

206 ng interacting species and few species-level coevolved traits) does not provide unequivocal support f

207 mmalian immune system and the nervous system coevolved under the influence of infection and sterile i

208 uggesting that the driver and suppressor are coevolving under an evolutionary "arms race." None of th

209 ognate partners are rare because SK/RR pairs coevolve unique interfaces that dictate phosphotransfer

210 pecificity while relaxing the constraints on coevolving unique contact interfaces.

211 s mykiss (rainbow trout), with variants of a coevolved viral pathogen, infectious hematopoietic necro

212 dentity of mammals is defined in part by our coevolved virome, a concept with profound implications f

213 hether the nuclear and mitochondrial genomes coevolved will need a thorough investigation of the hund

214 How pathogens coevolve with and adapt to their hosts are critical to u

215 re conclusions about which parts of galaxies coevolve with black holes, possibly by being regulated b

216 global processes, so the biggest black holes coevolve with bulges, but growth of the latter is driven

217 Since centromeric histones coevolve with centromeric satellites, these proteins wou

218 ers, global partner switching preference can coevolve with cooperation.

219 th successive flexible lines of defense that coevolve with corresponding offensive lines of the paras

220 locally and stochastically, and they do not coevolve with disks and pseudobulges.

221 Evolutionary rates and selection pressure coevolve with macrostructural and microstructural change

222 ale preferences are thought to originate and coevolve with male traits.

223 Multicellular eukaryotes coevolve with microbial pathogens, which exert strong se

224 Occasionally, Gag sequences also coevolve with mutations at PR cleavage sites contributin

225 ndicative of constraints on their ability to coevolve with pathogen effectors.

226 rosomycin genes, suggesting that they do not coevolve with pathogens.

227 Occasionally, Gag sequences also mutate and coevolve with protease, contributing to maintenance of v

228 The ability of the immune system to coevolve with the microbiota during postnatal life allow

229 of RPS5, indicating that the LRR domain must coevolve with the NBS domain.

230 at which these pathways converge, appears to coevolve with the occurrence of trp and his genes.

231 We argue kinematics coevolve with the secondarily terrestrial lifestyle of t

232 e is known about whether such a capacity can coevolve with the social behavior it supports.

233 d not threonylate , suggesting that MST1 has coevolved with .

234 propose that cannabinoid receptors initially coevolved with a fatty acid ester ligand (akin to 2-AG)

235 The human host coevolved with a normal microbiota over millennia and de

236 Multiple gestations seem to have coevolved with a suite of reproductive adaptations, incl

237 ur data suggest that HPV58 variants may have coevolved with archaic hominins and dispersed across the

238 ht be key antiviral factors of bats and have coevolved with bat-borne viruses.

239 These genes created and coevolved with biogeochemical cycles and were passed fro

240 al proteins showing that the rRNA signatures coevolved with both domain-specific and universal riboso

241 witch-like assembly mechanisms that may have coevolved with branch-specific groups of cytoplasmic eff

242 x assembly >300 bp away and how coregulation coevolved with coding sequences.

243 Manchurian ash (Fraxinus mandshurica), which coevolved with EAB, is more resistant than evolutionaril

244 was far higher when both bacterium and phage coevolved with each other than when phage evolved agains

245 itted behavior observed in some primates has coevolved with enlarged brains, complex sociality, and e

246 sidues of the gp120 inner domain layers have coevolved with H375 in order to maintain its ability to

247 ted with helicases in the replisome may have coevolved with helicases to increase the unwinding proce

248 ted hosts does not imply that symbionts have coevolved with hosts, let alone that they have evolved f

249 Our immune system has coevolved with infectious agents.

250 and their host cells, the murine strain has coevolved with its murine host by producing a large toxi

251 consider that chlorophyll degradation likely coevolved with land plants.

252 cal agents of tuberculosis and leprosy, have coevolved with mammals for millions of years and have nu

253 rangements to indicate that somatic mutation coevolved with mechanisms that select B cells based upon

254 e sole vectors of African trypanosomes, have coevolved with mutualistic endosymbiont Wigglesworthia g

255 s have modified life on this planet and have coevolved with myriad other species, including microorga

256 appears that Mexican Solanum species, which coevolved with P. infestans and were previously known fo

257 Placental development and genomic imprinting coevolved with parental conflict over resource distribut

258 on of cooperation: conditional harm may have coevolved with recognition first, thereby helping to est

259 hether stimulation by the inhibitory protein coevolved with resistance or whether it was acquired aft

260 reliance on culturally transmitted behavior coevolved with sociality and extended lifespan in primat

261 e unusual bias against ACA in tmRNA may have coevolved with the acquisition of MazF.

262 Sexual reproduction in Volvocine algae coevolved with the acquisition of multicellularity.

263 ve traditionally been class specific, having coevolved with the antibiotics they inactivate.

264 SepSecS and PSTK coevolved with the archaeal and eukaryotic lineages, but

265 ins of life, and these regulatory mechanisms coevolved with the basal transcription machinery.

266 suggesting that the catalytic core may have coevolved with the C-tail in AGC kinases.

267 The human host has coevolved with the collective of bacteria species, terme

268 te ancestor, whereas combinatorial diversity coevolved with the complex translocon organization.

269 is that, in plants, this signaling mechanism coevolved with the embryophytic life cycle and the acqui

270 pore complexes (NPCs) and nuclear membranes coevolved with the endomembrane system, and that the las

271 us fraction of rare hematopoietic cells that coevolved with the formation of the adaptive immune syst

272 e gut, referred as the commensal microbiota, coevolved with the host and is essential for many host p

273 lectively known as the gut microbiota, which coevolved with the host in a mutually beneficial relatio

274 rich gastrointestinal microbiota, which has coevolved with the host over millennia and is essential

275 M. tuberculosis has coevolved with the human host to evade and exploit host

276 vities at one region per chromosome may have coevolved with the loss of a point centromere to safegua

277 that the architecture of piRNA clusters has coevolved with the transposons that they are tasked to c

278 at variation in bitter taste sensitivity has coevolved with the use of spices in cooking, which, in t

279 Gammaherpesviruses coevolved with the vertebrate immune systems, establishi

280 s (P < 0.01), suggesting that Polyomaviridae coevolved with their avian and mammal hosts.

281 ection in highly adapted pathogens that have coevolved with their host.

282 of the order Rickettsiales have inextricably coevolved with their various eukaryotic hosts, resulting

283 modification from guanosine to queuosine has coevolved with these genomic changes.

284 ies are revealing how the gut microbiota has coevolved with us and how it manipulates and complements

285 Our results show that phenotypic diversity coevolves with contingent cooperation under a wide range

286 Gecko adhesion coevolves with modified muscles, tendons, and reflexes.

287 ion, with a focus on immune programming that coevolves with the developing microbiome early in life.

288 esource partitioning, we found that cheating coevolves with the ecological specialization toward asso

289 ganic anions and determine how the structure coevolves with the emission properties using solution as

290 patterns, with callitrichine miniaturization coevolving with a series of reproductive adaptations.

291 of transcription factor amino acids that are coevolving with nucleotides in their DNA-binding targets

292 ommon, consistent with both of these regions coevolving with pathogens.

293 itive selection, suggesting that they may be coevolving with pathogens.

294 acterial generations, 25% of the populations coevolving with phages had evolved 10- to 100-fold incre

295 roups rather than as individual host species coevolving with single pathovars.

296 ssion of a single classical MHC class I gene coevolving with TAP transporters, whereas class I genes

297 rapidly, raising the possibility that it is coevolving with target RNA elements.

298 that there exists another orientation field coevolving with the cells and reinforcing their alignmen

299 X) resistance among garter snake populations coevolving with toxic newts.

300 cts in different fields-especially when they coevolve-within the same physical system.