ライフサイエンスコーパス: coinfection

1 10 with HCV and human immunodeficiency virus coinfection).

2 ents tested positive for 2 or all 3 viruses (coinfections).

3 (VL) and human immunodeficiency virus (HIV) coinfection.

4 HIV)-infected cohorts, including 1 with KSHV coinfection.

5 patients with hepatitis C virus (HCV)/HIV-1 coinfection.

6 ates of fibrosis in individuals with HIV-HCV coinfection.

7 line was not modified by virus type, load or coinfection.

8 V-induced immunosuppression and Pneumocystis coinfection.

9 ontext of human immunodeficiency virus (HIV) coinfection.

10 treatment strategies in persons with HIV/HCV coinfection.

11 activation during HCV infection and HCV-HIV coinfection.

12 cella-zoster virus or herpes-simplex virus 1 coinfection.

13 .0276), particularly in TB patients with HIV coinfection.

14 ects of treating HCV in individuals with HIV coinfection.

15 es and significant liver fibrosis in HIV-HCV coinfection.

16 protein, and BaMV RNA are recruited with HV coinfection.

17 ulates Mtb-specific responses in helminth-TB coinfection.

18 deficiency virus (SIV), recapitulating human coinfection.

19 activity is not required for invasion during coinfection.

20 (cART) in up to 25% of patients with HIV/TB coinfection.

21 tly blocks initiation of this pathway during coinfection.

22 es in mosquitoes are only mildly affected by coinfection.

23 of both organisms to the bloodstream during coinfection.

24 tect WT animals from influenza and S. aureus coinfection.

25 significantly improved animal survival from coinfection.

26 al transmission without the effects of viral coinfection.

27 dence of a synergistic effect due to HIV/HCV coinfection.

28 standard for assessing prognosis in HIV/HCV coinfection.

29 irth, tribal scarring, and hepatitis B virus coinfection.

30 of MACV and LASV were not affected by virus coinfection.

31 recombinants following in vitro and in vivo coinfection.

32 heimia corymbifera, and Saksenaea vasiformis coinfection.

33 n HIV-positive individuals with active GBV-C coinfection.

34 with odds 90% higher in the presence of HIV coinfection.

35 evaluation in patients with HIV/tuberculosis coinfection.

36 urosepsis, and human immunodeficiency virus coinfection.

37 outcomes (PROs) in individuals with HIV/HCV coinfection.

38 ficiency virus (HIV)/hepatitis C virus (HCV) coinfection.

39 A minority (15%) also had urethral chlamydia coinfection.

40 tients without evidence of tuberculosis (TB) coinfection.

41 en Brucella and Legionella during macrophage coinfection.

42 sity was more limited following heterologous coinfection.

43 leaf miner infestation, bleeding canker, or coinfection.

44 nts, up to one-third of these have bacterial coinfection.

45 of inflammatory conditions seen with HIV/HCV coinfection.

46 abolome promotes susceptibility to bacterial coinfection.

47 ntial negative consequences of HIV/T. gondii coinfection.

48 fection to determine if IL-18 increases with coinfection.

49 o +1.7) and was similar with and without HBV coinfection.

50 paradigm for the study of other vector-borne coinfections.

51 tagenomic methods identified human pegivirus coinfections.

52 apeutic strategies to combat viral-bacterial coinfections.

53 t proportion of Ebola virus-malaria parasite coinfections.

54 ly depend on the age at primary exposure and coinfections.

55 detailed epidemiological data of interacting coinfections.

56 interventions that mitigate the severity of coinfections.

57 indow for genome reassortment from same-cell coinfections.

58 with diarrhea both as monoinfections and as coinfections.

59 Severity of diarrhea was not affected by coinfections.

60 : 57 with HCV monoinfection, 70 with HIV/HCV coinfection, 122 with HIV monoinfection, and 107 with ne

61 Eighteen men (27.3%) had acute HCV and HIV coinfection, 22 (33.3%) had chronic HCV infection and HI

62 (19.3%), hepatitis B (19%), and hepatitis C coinfection (3.3%), with more than one pathology in 16.2

63 ll drug-susceptible cases and those with HIV coinfection (54% and 52%, respectively, successfully com

64 ong 43 men (1.9%, 43/2228) with oral-genital coinfection, 60.5% (26/43) harbored an identical HPV typ

65 as identified in 22 of 25 children with MRSA coinfection (9 died) and 22 patients with MSSA coinfecti

66 ficiency virus (HIV)/hepatitis C virus (HCV) coinfection accelerates progressive liver fibrosis; howe

67 o this hypothesis, our results indicate that coinfection achieved through transmission supports high

68 was a significant risk for oral-genital HPV coinfection (Adjusted OR = 2.6, 95% CI: 1.0-7.0; 2 partn

69 infection (9 died) and 22 patients with MSSA coinfection (all survived).

70 In subanalyses accounting for coinfections, all associations were stronger and statist

71 n-Barr virus (EBV) and Plasmodium falciparum coinfection, although how P. falciparum exposure affects

72 y in a macaque model of sexually transmitted coinfection, although the infection of 2 macaques signal

73 acute febrile illness and identification of coinfections, although targeted arbovirus screening may

74 apparent approximately 60% prevalence of HDV coinfection among these HBV-infected Mongolian subjects,

75 nodeficiency virus (HIV) and hepatitis virus coinfection amplify and accelerate hepatic injury.

76 ion was stratified by viral hepatitis B or C coinfection and computer-generated.

77 HIV/HCV coinfection and elevated interleukin (IL)-18 levels are

78 , <40% of vaccinated mice survived bacterial coinfection and FcR-dependent clearance of antibody-opso

79 t also enhances C. albicans pathogenicity in coinfection and induces extrusion of the swimbladder.

80 automatic HCV RNA for Ab-positive patients, coinfection and liver health tests, vibration-controlled

81 Coinfection and passage of these SAT isolates in goat an

82 cine responses, increasing susceptibility to coinfection and potentially reducing tumor immunosurveil

83 each organism appears to be enhanced by some coinfections and weakened by others.

84 22 (33.3%) had chronic HCV infection and HIV coinfection, and 26 (39.4%) had chronic HCV monoinfectio

85 y in outcome, the probability of acquiring a coinfection, and the use of new therapeutic strategies t

86 for studies of HCV pathogenesis, lentivirus coinfection, and vaccine development.

87 esistance, may simplify therapy regimens for coinfections, and facilitates management of emerging vir

88 ly elevated during symptomatic and/or lethal coinfections, and hypothermia strongly correlated with m

89 ned for the presence of uncommon viruses and coinfections, and that most cases of indeterminate ALF i

90 Malaria and schistosomiasis coinfections are common, and chronic schistosomiasis has

91 roposed that reduced T cell responses during coinfections are due to diminished recruitment of naive

92 In conclusion, coinfections are frequent, and the pathogenicity of each

93 Coinfections are increasingly recognized as important dr

94 These coinfections are not independent processes or benign.

95 ng HCV infection, HIV infection, and HCV-HIV coinfection, as well as in uninfected controls, before a

96 blocked the MACV-triggered IFN response in a coinfection assay.

97 hin a coinfected cell and, given synchronous coinfection at moderate or high doses, can give rise to

98 us reassortment, including the likelihood of coinfection at the host and cellular levels, mixing and

99 ents with human immunodeficiency virus (HIV) coinfection, barriers to LT exist.

100 on for HIV-infected patients with HBV or HCV coinfection but undetectable HCV RNA.

101 Reinfection may be higher in HIV-HCV coinfection, but prior studies have considered small sel

102 munodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are

103 hin hosts, parasite growth was influenced by coinfections, but coinfections were often prevented by p

104 rticles are recovered from a single round of coinfection by AD169 and Towne strain viruses, consisten

105 Coinfection by HBoV1 and AAV2 rescued AAV2 replication i

106 Coinfection by HIV-1 promotes the aggressive growth of K

107 een immune responses elicited during chronic coinfection by multiple herpesviruses.

108 ess the effects of airway insults, including coinfections by recognized respiratory pathogens.

109 Coinfections by Streptococcus pneumoniae and nontypeable

110 th death warrants increased awareness of IPD coinfection caused by two or more serotypes.

111 commensal colonization, and influenza virus coinfection caused S. pneumoniae NP density to increase,

112 F0/F1 to F4, without liver complications or coinfections, chronically infected by HCV, and treated w

113 ir/sofosbuvir, respectively, to the Canadian Coinfection Cohort, representing approximately 23% of th

114 Thus, our results suggest that HIV coinfection compromises CD8+ T-cell functions in latent

115 ortant genotypes produced under single-cycle coinfection conditions showed a strong preference for ho

116 Human studies suggest that helminth coinfections contribute to increased TB susceptibility a

117 populations, including patients with HIV/HCV coinfection, decompensated cirrhosis, liver and kidney t

118 Because HIV coinfection does not affect SVR rates or toxicity with D

119 nsight into the mechanisms by which helminth coinfections drive increased susceptibility, disease pro

120 Our findings suggest that H. pylori coinfection effectuates a systemic immune modulatory eff

121 HIV coinfection enhanced C4 activation and consumption in pa

122 These coinfection events were experimentally demonstrated to o

123 Coinfection experiments revealed that LASV could potentl

124 In addition, during coinfection experiments with Legionella pneumophila, we

125 with human immunodeficiency virus (HIV)-HCV coinfection given SL8 in a real-world setting.

126 was not associated with severe disease, ADV coinfection had increased odds of life-threatening disea

127 4; 95% CI, 1.6-7.2; P = .001), and influenza coinfection had increased odds of life-threatening disea

128 Patients with HBV coinfection had survival of 80% at 1, 3, and 5 years aft

129 Among patients with HCV coinfection, HCV RNA replication status at retransplanta

130 uded those with human immunodeficiency virus coinfection, hepatitis B surface antigen positivity, cir

131 d without human immunodeficiency virus (HIV) coinfection; however, in the ION-4 study, black patients

132 diversity was observed among progeny of both coinfections; however, diversity was more limited follow

133 idence interval [CI], 1.41-1.52) and HIV/HCV coinfection (HR 2.62, 95% CI, 2.06-3.33) were associated

134 With simultaneous coinfection, HSV-2 significantly stimulated HIV-1 DNA pr

135 ic propagation in the context of synergistic coinfections if the strength of the coupling matches tha

136 otential effect of Acanthamoeba-endosymbiont coinfection in a human corneal tissue model representing

137 nsoni attenuates the severity of P. knowlesi coinfection in baboons by mechanisms that may enhance in

138 Helicobacter pylori coinfection in human immunodeficiency virus (HIV) patien

139 data support an increase in the frequency of coinfection in human patients, raising the likelihood th

140 t, including pre-exposure prophylaxis of HBV coinfection in the HIV infected.

141 ce of HEV/human immunodeficiency virus (HIV) coinfection in U.S.

142 supports a potential independent role of CMV coinfection in vascular/degenerative organ disorders in

143 pathogens and assessed interactions between coinfections in additive and multiplicative models.

144 cy virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and

145 patients with HCV of any genotype and HIV-1 coinfection, including those with compensated cirrhosis.

146 We aimed to determine whether viral coinfections increased life-threatening disease in a lar

147 Together, our data indicate that helminth coinfection induces arginase-1-expressing type 2 granulo

148 r coinfection occurring in patients, and how coinfections influence the outcome of leishmaniasis is p

149 ynx (NP) colonization density during a viral coinfection initiates pathogenesis.

150 onoinfection and HIV/hepatitis C virus (HCV) coinfection is associated with an enhanced liver fibrosi

151 e that the inefficacy of antibiotics against coinfection is attributable to oxidative stress-associat

152 HIV/hepatitis C virus (HCV) coinfection is frequent, but evidence supporting similar

153 ted cytokine responses in S. stercoralis-LTB coinfection is reversible (for the most part) by anthelm

154 cute genotype 1 or 4 HCV infection and HIV-1 coinfection is similar to historic rates with interferon

155 HIV coinfection is the most prominent risk factor for progre

156 lpha-toxin in pediatric staphylococcal-viral coinfection is unclear.

157 Accordingly, HEV-HIV coinfection leads to accelerated liver cirrhosis and inc

158 Older age, intravenous drug use, hepatitis C coinfection, lower baseline eGFR, female gender, lower C

159 Although TB-NTM coinfection may have been underdiagnosed, our results su

160 esult in similar clinical presentations, and coinfections may be relatively common.

161 Among 463 patients analyzed (61 with HBV coinfection), median age was 35 years, 53.7% were women,

162 In the mouse coinfection model this was accompanied by increased fung

163 A murine helminth/RSV coinfection model was developed.

164 ure of the disease, there is a high risk for coinfection occurring in patients, and how coinfections

165 ortant viruses were generated during natural coinfection of a patient with pandemic H1N1 (2009) and s

166 ics of multiple diseases interacting through coinfection of a single individual, two problems typical

167 to examine norovirus recombination following coinfection of an animal and suggests that the exchange

168 However, the potential for coinfection of dogs and possible reassortment of human a

169 ited by other herpesviruses and the frequent coinfection of HIV-positive individuals by KSHV, we soug

170 fluenza A viruses is readily observed during coinfection of host animals and in vitro; however, repor

171 Further, LCMV coinfection of IFN-gamma-deficient mice promoted parasit

172 We investigated whether coinfection of macaques with Chlamydia trachomatis and T

173 Remarkably, LCMV coinfection of mice that had healed from L. guyanensis i

174 sequence rare recombinants arising from the coinfection of mice with two distinct strains of murine

175 Finally, we demonstrated that coinfection of mouse footpads or rabbit eyes with rAAV v

176 Following coinfection of naive African buffaloes with isolates of

177 We develop a mean-field model of coinfection of two diseases following susceptible-infect

178 Coinfections of identical HPV types were rare, suggestin

179 pressed the replication of vac2, as shown by coinfections of interferon-incompetent lymphatic cells w

180 Aside from CHIKV and ZIKV, coinfections of other viral pathogens were not detected.

181 Chronic coinfections of Staphylococcus aureus and Pseudomonas ae

182 A total of 306 participants (62% with HIV-1 coinfection, of whom 71% received antiretroviral therapy

183 nts with and without hepatitis B virus (HBV) coinfection on antiretroviral therapy (ART) in Zambia.

184 paryphium sp.), we examined the influence of coinfection on disease outcomes.

185 The impact of coinfection on the ability of relevant vector species to

186 To define the effect of HIV coinfection on the anti-HCV antibody response, we measur

187 to reverse the negative effects of helminth coinfection on the CD8 T cell response.

188 r fibrosis severity in patients with HIV/HCV coinfection, on chromosome 3p25, a finding that was repl

189 b infection, we demonstrated that S. mansoni coinfection or immunization with S. mansoni egg antigens

190 IV monoinfection, HCV monoinfection, HIV/HCV coinfection, or people who inject drugs with neither inf

191 contribution of enhanced urease activity to coinfection pathogenesis, and screened for enhanced urea

192 Virus load, age, and malaria parasite coinfection play a role in the outcome of EVD.

193 Increased age, male sex, and HBV coinfection predicted significant fibrosis/cirrhosis at

194 rence occurs (i.e., HIV or hepatitis D virus coinfection, preexisting drug resistance), those with a

195 Human immunodeficiency virus coinfection (prevalence ratio [PR] = 0.63; 95% confidenc

196 er BMI, IV drug use, lower baseline CD4, HCV coinfection, prior osteonecrosis, prior fracture, cardio

197 risk, likely due to high human herpesvirus 8 coinfection rates.

198 in pregnant HIV-infected women with helminth coinfections receiving ART.

199 tation corresponding to these two CHIKV/ZIKV coinfections reflected infection by the virus present at

200 ther adjustment for liver stiffness, HIV/HCV coinfection remained associated with 6% higher levels (9

201 actors and for inflammatory markers, HIV/HCV coinfection remained associated with a 9% higher ELF sco

202 HCV monoinfection and HIV/HCV coinfection remained strongly associated with lower LFF

203 Multidrug-resistant TB and HIV coinfection represent severe threats to TB control effec

204 Multicycle coinfection results corroborated these findings and reve

205 HIV/HCV coinfection results in significantly elevated serum IL-1

206 s acute lung injury and primes for bacterial coinfections revealing potential insights into the patho

207 When such exposure led to coinfection, robust reassortment was typically seen, wit

208 may be warranted to further understand this coinfection scenario, improve cervical health, and reduc

209 th suspected ZIKV infection for dengue virus coinfection should be considered in dengue-endemic count

210 pies to inhibit HIV-1 infection during HSV-2 coinfection should contribute to reducing HIV-1 transmis

211 Stratified by HBV coinfection status (hepatitis B surface antigen positive

212 Coinfection studies determined that the presence of thes

213 he need to consider this inequality in human coinfection studies.

214 these changes influence B cell responses to coinfections such as malaria is poorly understood.

215 ungal, bacterial, and immune dynamics during coinfection suggest that enhanced morbidity is associate

216 regarding treatment of persons with HIV/HCV coinfection suggest that HCV treatment should be a prior

217 rus, mean viremia was significantly lower in coinfections than in monoinfections.

218 s of liver fibrosis in patients with HIV/HCV coinfection that may help define new targets for drug de

219 We show by coinfection that the C-defective phenotype is dominant.

220 Among men with acute HCV and HIV coinfection, the median HCV RNA level in blood specimens

221 s) from persons with HIV and M. tuberculosis coinfection, those with HIV monoinfection, and those wit

222 hesis that reassortment efficiency following coinfection through transmission would be reduced compar

223 They provide insight into coinfection timing, the heterogeneity in outcome, the pr

224 HDV requires a hepatitis B virus (HBV) coinfection to provide HDV with HBV surface antigen enve

225 Patients with HIV/HCV coinfection tolerate interferon-free sofosbuvir-based an

226 atening disease in RSV-ADV and RSV-influenza coinfection warrants further study.

227 In the first, coinfection was achieved by exposing a naive guinea pig

228 Coinfection was associated with increased spontaneous pr

229 However, Nox2-induced lung damage during coinfection was not associated with aggravated inflammat

230 Virus type or coinfection was not associated with disease severity.

231 RSV and any other viral coinfection was not associated with severe disease, ADV

232 HIV coinfection was present in 34% of samples, and 25% were

233 HCV/HIV coinfection was the main factor associated with hepatic

234 Hepatitis C virus (HCV) coinfection was the main factor associated with nADEs in

235 Prevalence of coinfections was 58.1% in cases and 40.4% in controls.

236 two murine norovirus (MNV) strains to model coinfection, we developed a microfluidic platform to amp

237 human immunodeficiency virus type 1 (HIV-1) coinfection, we measured the plasma levels of 22 cytokin

238 onoinfection, HCV monoinfection, and HIV/HCV coinfection were associated with 19% (95% confidence int

239 V-nontransmitting women with chronic CMV/HIV coinfection were evaluated for the ability to predict th

240 treatment guidelines regarding SCD with HIV coinfection were identified.

241 g children aged 5-14 years, malaria parasite coinfection were independent determinants of a poor EVD

242 iants (RAVs), mixed HCV genotypes, and other coinfections were compared using a panel of samples with

243 amydia trachomatis and Mycoplasma genitalium coinfections were evaluated using nucleic acid amplifica

244 e growth was influenced by coinfections, but coinfections were often prevented by priority effects am

245 IL-15) were found to be elevated in HIV/HCV coinfection when compared to both monoinfections.

246 on models have depended on influenza A virus coinfection, which greatly enhances pneumococcal sheddin

247 CMV coinfection, which represents a potential target for the

248 In contrast, coinfection with a C-protein-expressing virus did not co

249 us, and productive AAV2 replication requires coinfection with a helper virus (e.g., adenovirus or her

250 ual's fever remains unknown due to potential coinfection with a non-malarial febrile illness.

251 Coinfection with a secreted aspartyl protease (sap) muta

252 nation, and in most cases, it is reported as coinfection with A. marginale without characterization o

253 IFIT1 sensitivity of PIV5 was not rescued by coinfection with an IFIT1-resistant virus (PIV3), demons

254 RSV coinfection with any respiratory virus is not associated

255 s, reservoir hosts, and humans indicate that coinfection with B. burgdorferi and B. microti is common

256 Coinfection with genetic variants of human cytomegalovir

257 opes from the immediate early 1 gene of CMV, coinfection with genetically distinct variants of CMV wa

258 survival defects of H. parainfluenzae during coinfection with H. influenzae are topics for future wor

259 The results showed that coinfection with H. influenzae promoted clearance of H.

260 es simplex virus type 1, including 1 case of coinfection with HBV, and 1 case each of HBV, parvovirus

261 Coinfection with hepatitis C virus (HCV) is a particular

262 Coinfection with HIV is the single greatest risk factor

263 addition to clinico-demographic predictors, coinfection with HIV was associated with PRO impairment

264 Therefore, we examined the effects of coinfection with HIV-1 and HSV-2 on monocyte-derived DCs

265 es were compared to those obtained following coinfection with homologous, genetically tagged, pH1N1 v

266 Coinfection with human immunodeficiency virus (HIV) and

267 us viral elements (dsRNA/LRV1), or exogenous coinfection with IFN-inducing viruses, are able to syner

268 Coinfection with influenza A virus, which also expresses

269 that it is not a redundant bystander during coinfection with influenza A virus.

270 Thus, one might predict that coinfection with LCMV, which induces a strong systemic t

271 After coinfection with NC/02 or MN/99 plus TX/96, H1/H3 double

272 Coinfection with neuraminidase-expressing influenza viru

273 After adjustment for HPV31 lineages, coinfection with other oncogenic types, and the timing o

274 on in cattle trachea, which could facilitate coinfection with other pathogens, and in doing so, predi

275 We previously demonstrated that coinfection with P. mirabilis and P. stuartii increased

276 and resulted in lower numbers in response to coinfection with P. yoelii.

277 M. tuberculosis infection and untreated HIV coinfection with preserved CD4+ T-cell counts.

278 Their role in coinfection with respiratory viruses is not clear.

279 insic lipopolysaccharide stimulation or upon coinfection with Salmonella enterica serovar Typhimurium

280 in why HIV-1 acquisition is increased during coinfection with sexually transmitted infections.

281 n addition our analysis provide evidence for coinfection with Streptococcus (S.) pneumoniae.

282 In this study, we investigated the impact of coinfection with T. gondii on the innate virus-directed

283 The association of HIV and HIV/HCV coinfection with the ELF score was evaluated using multi

284 ow-fidelity variants retained fitness during coinfection with the wild-type virus.

285 Using coinfection with two natural mouse pathogens, Heligmosom

286 Using coinfection with two natural mouse pathogens, Heligsomos

287 B. neotomae were significantly stimulated by coinfection with wild-type but not T4SS mutant L. pneumo

288 role in the impaired Th1 responses observed coinfection with worms.

289 igh prevalence in African AGMs, and frequent coinfections with as many as 11 distinct variants.

290 , from April 2015 to January 2016 identified coinfections with chikungunya virus (CHIKV) in 2 of 15 Z

291 rial TcPAb preparations can be used to treat coinfections with divergent pathogens, demonstrating tha

292 Our study reveals a high level of enteric coinfections with diverse viruses in a captive rhesus ma

293 Coinfections with members of up to six viral families we

294 ates of Mycoplasma genitalium infections and coinfections with other sexually transmitted organisms a

295 ium single infections, a lower prevalence of coinfections with other sexually transmitted organisms,

296 al virus (RSV) or rhinovirus (RV), including coinfections with other viruses.

297 Results of heterologous coinfections with pH1N1 and H3N2 viruses were compared t

298 Safety and efficacy against coinfections with soil-transmitted helminths and Opistho

299 cts with human immunodeficiency virus type 1 coinfection without documented opportunistic infections.

300 n two immune responses during a simultaneous coinfection would significantly alter CD8 T cell memory