ライフサイエンスコーパス: comorbid

1 are typically chronic, disabling, and highly comorbid.

2 blic health burdens, and they are frequently comorbid.

3 the PSENEN mutation carriers presented with comorbid acne inversa (AI), an inflammatory hair follicl

4 [OR] 0.40, CI 0.28-0.57) and increased with comorbid acquired immunodeficiency syndrome (OR 4.52, CI

5 information is available on how primary and comorbid acute myocardial infarction contribute to the m

6 ith AD-only (n = 42), ADHD-only (n = 34) and comorbid AD + ADHD (n = 31) had significantly increased

7 To detect genetic risk variants for comorbid AD and MD and to determine whether polygenic ri

8 sociation study analyzed criterion counts of comorbid AD and MD in African American and European Amer

9 significantly and replicably associated with comorbid AD and MD in African American participants.

10 ment of medications and other treatments for comorbid AD and MD.

11 rican participants could be used to estimate comorbid AD and MD.

12 l characteristics of children with AD, ADHD, comorbid AD/ADHD and age-matched healthy controls and to

13 of people with bipolar disorder suffer from comorbid ADHD.

14 ars, P = 0.013) and were more likely to have comorbid allergic disease.

15 lergen sensitization and high frequencies of comorbid allergic diseases are characteristic of severe

16 miniAQLQ scores were worse in patients with comorbid allergy (P = 0.045) and chronic obstructive pul

17 ll survival in groups with varying levels of comorbid Alzheimer's disease pathology according to US N

18 eep disorders and substance abuse are highly comorbid and we have previously shown that methamphetami

19 DSM-5 DUD is a common, highly comorbid, and disabling disorder that largely goes untre

20 pting GPs to routinely screen for and manage comorbid anxiety and depression in patients presenting w

21 vs 65% of Subgroup A; chi(2)=3.89, p=0.049), comorbid anxiety diagnoses (42.9% of Subgroup B vs 17.5%

22 oman, higher parental education and having a comorbid anxiety disorder were protective factors.

23 Comorbid anxiety disorders were more likely in psychosis

24 After the exclusion of persons with comorbid anxiety disorders, depression, or substance use

25 Comorbid anxiety disorders, depression, or substance use

26 ildren with ADHD (n = 93), and children with comorbid ASD and ADHD (n = 66).

27 with CRS, both with and without polyps, and comorbid asthma completed the Mini Asthma QOL Questionna

28 4 years [9.4 years]; 34 men [56.7%]; 35 with comorbid asthma), 51 completed the study.

29 with chronic rhinosinusitis (CRS) often have comorbid asthma.

30 While there was no association with comorbid attention-deficit/hyperactivity disorder or IQ,

31 comparison models or after the exclusion of comorbid attention-deficit/hyperactivity disorder.

32 nclude that prenatal insults alone can cause comorbid autism and epilepsy but it requires a combinati

33 The risk was somewhat elevated for ADHD with comorbid autism spectrum disorder (OR, 1.76; 95% CI, 1.3

34 Exclusion of ADHD cases with comorbid autism spectrum disorder attenuated but did not

35 immune cells; antibodies, autoantibodies and comorbid autoimmune disorders; complement; oxidative str

36 After adjusting for year, age, and comorbid burden, males remained at 17% increased risk ve

37 ent facility location, travel distance), and comorbid (Charlson-Deyo score) factors and year of diagn

38 arly effective in people with depression and comorbid chronic physical conditions.

39 emonstrate a novel role for G9a in promoting comorbid cocaine addiction and anxiety and suggest that

40 Therefore, CKD remains an important comorbid condition in the HIV-positive population and an

41 only 2 conditions (presence of purulence and comorbid condition of asthma) were associated with signi

42 D), especially among those who also have the comorbid condition of epilepsy or intellectual disabilit

43 s management includes understanding HIV as a comorbid condition with a spectrum of impact that is uni

44 bid conditions or 32 or more with at least 1 comorbid condition) from a weight management program and

45 44 of 3478 [53.0%]), and individuals without comorbid conditions (1795 of 2464 [72.8%] vs 1978 of 302

46 CI, 1.03-1.06), increased number of chronic comorbid conditions (IRR, 1.12; 95% CI, 1.06-1.19), and

47 s, including cardiovascular risk factors and comorbid conditions (such as cancer, chronic kidney dise

48 After the age-sex-race adjustment, comorbid conditions and health-care utilization were sim

49 ite (29% vs 6%), with a higher prevalence of comorbid conditions and more frequent presentation with

50 plexity of sepsis syndromes in relation with comorbid conditions and raises the question of the relev

51 th events; however, in analyses adjusted for comorbid conditions and socioeconomic status, blacks had

52 ccumulated a significantly greater burden of comorbid conditions and suffered greater pain associated

53 We evaluated the association between common comorbid conditions and the development of peripheral ne

54 Comorbid conditions can be pulmonary or extrapulmonary.

55 Comorbid conditions can play a role in the reporting of

56 From those studies, we identified 428 comorbid conditions co-occurring in individuals with FAS

57 These patients had similar comorbid conditions compared with patients without infla

58 To estimate the pooled prevalence of comorbid conditions found to co-occur in individuals wit

59 The high prevalence of comorbid conditions in individuals with FASD highlights

60 Elderly patients with minimal comorbid conditions meeting the inclusion criteria of th

61 nts with CD have extra-intestinal autoimmune comorbid conditions more frequently than expected.

62 h FASD and estimate the pooled prevalence of comorbid conditions occurring in individuals with fetal

63 ; and preextracorporeal membrane oxygenation comorbid conditions of cardiac arrest, cancer, renal and

64 The comorbid conditions of patients with cancer affect treat

65 ght in meters squared] of 35 or more with no comorbid conditions or 32 or more with at least 1 comorb

66 the study include an inability to adjust for comorbid conditions or demographics known to impact fibr

67 initial treatment options and those who have comorbid conditions or psychological symptoms, a combina

68 The presence of comorbid conditions rather than valve performance affect

69 However, the pathogenesis of these comorbid conditions remains unclear and it remains diffi

70 Patients with comorbid conditions requiring warfarin were excluded.

71 Although some of these comorbid conditions share risk factors with IPF, the lik

72 The burden of comorbid conditions should be considered in developing e

73 with an ECOG PS >/= 3 and poorly controlled comorbid conditions should be offered cancer-directed th

74 d VTE, which is potentially mediated through comorbid conditions such as cancer, the modifiable tradi

75 e who did not die were younger and had fewer comorbid conditions than did those who died of causes ot

76 IBD patients had a higher prevalence of comorbid conditions than matched general population cont

77 We aimed to identify the comorbid conditions that co-occur in individuals with FA

78 ed and divided into five categories based on comorbid conditions that have been associated with music

79 the use of surrogate markers of frailty and comorbid conditions to identify patients at highest risk

80 includes the identification and treatment of comorbid conditions to optimise patient outcomes.

81 n, 3.7; range, 0-53), and the mean number of comorbid conditions was 3.3 (median, 2.8; range, 0-34).

82 odemographics, 2) behavioral factors, and 3) comorbid conditions were assessed using prevalence ratio

83 Most chronic comorbid conditions were musculoskeletal or ambulation (

84 The proportions of comorbid conditions were similar in male and female subj

85 The five comorbid conditions with the highest pooled prevalence (

86 justment for age, PSI score, and preexisting comorbid conditions).

87 te alcohol use, fewer prior surgeries, fewer comorbid conditions, absence of depression, and less sev

88 tinued morbidity, including a high degree of comorbid conditions, allergic sensitization, exacerbatio

89 were elderly (mean age, 71 years), often had comorbid conditions, and 16% had difficulty with >/=1 ac

90 nce with routine vaccinations, management of comorbid conditions, and adherence to treatment regimens

91 l-level risk factors included age, number of comorbid conditions, and antibiotic exposure.

92 (CIED) recipients are elderly, have multiple comorbid conditions, and are at increased risk of CIED i

93 s, donation service area, dialysis duration, comorbid conditions, and body mass index.

94 ts on NOACs or warfarin were older, had more comorbid conditions, and experienced more severe strokes

95 es a focus on the interaction between aging, comorbid conditions, and HIV-1.

96 n multivariable analysis, younger age, fewer comorbid conditions, and in-hospital procedures such as

97 ic regression models to adjust for age, sex, comorbid conditions, and stroke type and severity.

98 Baseline demographics, comorbid conditions, clinical risk scores, and renal fun

99 tion included male sex, increased age, fewer comorbid conditions, complicated biliary disease on init

100 In hypothesis-free exploration of comorbid conditions, disease-disease networks are usuall

101 tion of this substrate may vary depending on comorbid conditions, genetics, sex, and other factors.

102 After considering covariates, including comorbid conditions, having early AMD at any age or havi

103 umans but markedly elevated in patients with comorbid conditions, including diabetes mellitus and hyp

104 pment and neurotransmission, and may explain comorbid conditions, including gastrointestinal disorder

105 Is; skin and soft-tissue infections; chronic comorbid conditions, including neurologic and respirator

106 bis-dependent participants (CD), free of any comorbid conditions, including nicotine use.

107 regression models adjusted for demographics, comorbid conditions, lifestyle and disability indicators

108 Injury mechanism and severity, comorbid conditions, mental health disorders, and demogr

109 Injury mechanism and severity, comorbid conditions, mental health disorders, and demogr

110 nment for the development or perpetuation of comorbid conditions, or alternatively that they share ca

111 did not differ statistically with regard to comorbid conditions, sources of bacteremia, or numbers o

112 a relatively diverse phenotype and frequent comorbid conditions, such as anxiety and depression.

113 osis, most patients with IPF have associated comorbid conditions, which might negatively affect funct

114 including chronic inflammation and multiple comorbid conditions, which undoubtedly contribute to the

115 pes comprising subgraphs of highly connected comorbid conditions.

116 ortion of AIAN cancer patients with multiple comorbid conditions.

117 ire, and a review of current medications and comorbid conditions.

118 aroscopic procedures were younger with fewer comorbid conditions.

119 cade, despite increases in DM prevalence and comorbid conditions.

120 ed risk of thromboembolic and cardiovascular comorbid conditions.

121 lp with the early detection and treatment of comorbid conditions.

122 ich was mitigated by adjusting for increased comorbid conditions.

123 years, and 92% had CCI > 0, indicating >/=1 comorbid conditions.

124 dir CD4(+) T-cell count, zidovudine use, and comorbid conditions.

125 ographic characteristics, PTSD, and physical comorbid conditions.

126 l injury severity, head injury severity, and comorbid conditions.

127 approach needs to be tailored addressing all comorbid conditions.

128 year, socioeconomic status, age, parity, and comorbid conditions.

129 ion and lower hormone levels, independent of comorbid conditions.

130 nts was high and reflective of high rates of comorbid conditions.

131 460 residents (64.2%) had 4 or more chronic comorbid conditions.

132 nfounding by smoking, underlying illness, or comorbid conditions.

133 ificant increase in each of these associated comorbid conditions: diabetes (4.6%-7.8%), hypertension

134 95 years (n = 32), 44% of whom had 5 or more comorbid conditions; family members of patients (n = 30)

135 with PAD were older and more likely to have comorbid conditions; however, mean P2Y12 reaction units

136 iatal abnormalities in ADHD may be caused by comorbid conduct disorder rather than ODD.

137 f AF were older and were more likely to have comorbid congestive heart failure, cardiomyopathy, cereb

138 Comorbid coronary artery disease (CAD) was present in 24

139 ean [SD] age, 40.1 [10.7] years), the median comorbid criterion count was 6.2 (interquartile range, 2

140 Comorbid criterion counts (ranging from 0 to 14) for AD

141 exercise capacity was strongly influenced by comorbid defects.

142 o investigate biopsychological mechanisms of comorbid depression in OCD, we examined effective connec

143 larly high after stroke; among patients with comorbid depression or diabetes, immigrants, and those n

144 h Parkinson's disease (PD) often suffer from comorbid depression.

145 severity of PD, especially in the context of comorbid depression.

146 f treatment and prevention strategies across comorbid depressive and somatic illnesses.

147 f severe disease in infancy; the presence of comorbid developmental abnormalities; and the possible l

148 D may be at especially high risk for certain comorbid developmental conditions (i.e., autism spectrum

149 Comorbid diabetes mellitus (DM) increases tuberculosis (

150 rom 2006 to 2010 to identify all primary and comorbid diagnoses of acute myocardial infarction during

151 Patients with comorbid diagnoses of acute myocardial infarction had tw

152 ew, including 1 or more diagnoses, 2 or more comorbid diagnoses, major depressive episode (current an

153 ing understanding of the development, common comorbid diagnoses, prognosis and treatment of these dis

154 in a second or subsequent encounter), was a comorbid diagnosis in 12 118 (18%), and was not mentione

155 rventions targeting functioning, or who have comorbid difficulties preventing them from doing so.

156 DSM-5 criteria is a highly prevalent, highly comorbid, disabling disorder that often goes untreated i

157 ac complication that may lead to substantial comorbid disease and premature mortality.

158 ted in large improvements in obesity-related comorbid disease and sustained weight loss over a 5-year

159 To evaluate effect on comorbid disease and weight loss 5 years after Roux-en-Y

160 acute coronary syndrome, but they had lower comorbid disease burden and were less likely to receive

161 All comorbid disease conditions were coded according to the

162 mes and demonstrate outstanding reduction in comorbid disease following RYGB.

163 need for targeted improved primary care and comorbid disease management.

164 ghly significant decrease in obesity-related comorbid disease persisted at 10 years of follow-up afte

165 brainstem or lacunar infarct, a substantial comorbid disease, an inability to undergo an MRI scan, o

166 weight loss and treatment of obesity-related comorbid disease.

167 esity (6.5% vs 10.6%, P < .001), or multiple comorbid diseases (% of patients with >/=2 comorbidities

168 raphic location, operation type, and certain comorbid diseases also predicted OD (P < 0.05).

169 We found 2158 significantly comorbid diseases for the EA cohort, 3265 for AA and 672

170 Comorbid diseases were most strongly associated with CRS

171 ifferentially affect asthma and obesity, two comorbid diseases where polarized macrophages contribute

172 -up was 100% (9774 eligible individuals) for comorbid diseases.

173 remedication and who had similar rates of 13 comorbid diseases.

174 in demographics, risk factors for ARDS, and comorbid diseases.

175 esent nonimpairing cognitive fluctuations, a comorbid disorder, or the cognitive effects of substance

176 ociation has changed over time or relates to comorbid disorders (eg, conduct disorder [CD], oppositio

177 en earlier and adult-onset MDD with commonly comorbid disorders of schizophrenia, bipolar disorder, A

178 relative age effect was not accounted for by comorbid disorders such as CD, ODD, or LD.

179 r migraine but potentially also for migraine-comorbid disorders such as epilepsy, depression, and str

180 ression and type 2 diabetes (T2D) are highly comorbid disorders that carry a large public health burd

181 clinical response relevant to these commonly comorbid disorders.

182 Cocaine addiction and depression are comorbid disorders.

183 tly suffer from both psychiatric and somatic comorbid disorders.

184 reatment intensity suggest selection of less comorbid elderly patients, indicating possible rationing

185 (endophenotype) for addictive disorders and comorbid externalizing psychopathology, particularly in

186 ed by the presence of multiple premorbid and comorbid factors affecting cognitive reserve that influe

187 ogical confounds or schizophrenia-associated comorbid factors, not present in monkeys chronically exp

188 tal immune activation can also produce these comorbid features in mice.

189 Parkinson's disease (PD) is highly comorbid for a spectrum of sleep disorders and deep brai

190 defined as the proportion of life expectancy comorbid-free, and was adjusted on the probability of oc

191 revious Giardia infection can be ascribed to comorbid functional disorders.

192 d using linear mixed models, controlling for comorbid functional dyspepsia.

193 rnally transmitted phenotype, reminiscent of comorbid generalized anxiety/depression, to elementary b

194 etwork organisation was most variable in the comorbid group, followed by patients with LLD-only.

195 Early emergence of comorbid hallucinations and delusions were observed in 5

196 rs of clinical TMD were simple checklists of comorbid health conditions and nonpainful orofacial symp

197 gistic, often deleterious interactions among comorbid health conditions, especially under circumstanc

198 til now, syndemic theory has been applied to comorbid health problems in poor immigrant communities i

199 aring loss alone or in skin pathologies with comorbid hearing loss.

200 lloid was initiated significantly later with comorbid heart failure and renal failure, with absence o

201 lie the cognitive dysregulation reported for comorbid humans.

202 re more likely to be older, female, and have comorbid hypertension, diabetes mellitus, dyslipidemia,

203 : (1) does comprehensive risk adjustment for comorbid illness and frailty measures explain the higher

204 Changes in population demographics and comorbid illness prevalence, improvements in medical car

205 New York Heart Association class III/IV, and comorbid illnesses were associated with declines in KCCQ

206 in the regulation of anxiety, which is often comorbid in these disorders.

207 th severe atopic dermatitis with and without comorbid infections, we found eight individuals, from fo

208 truction; approximately 75% of patients have comorbid inflammatory bowel disease (IBD).

209 Management involves assessment for comorbid inflammatory bowel disease and exclusion of oth

210 h both severe cerebral bleeding disorder and comorbid Keutel syndrome, a nonbleeding malady caused by

211 Patients with comorbid major depression were nine times more likely th

212 Randomization stratified for comorbid major depression.

213 e of psychotropic medication and presence of comorbid major depressive disorder were important modera

214 but remained significant after adjusting for comorbid major depressive disorder, anxiety disorder, an

215 ing MDD PRS using MDD GWAS data sets without comorbid MDD-AD cases, significant evidence was observed

216 In humans, ASD is frequently associated with comorbid medical conditions including sleep disorders, m

217 behaviors, physical impairments, surgeries, comorbid medical conditions, medications, and MFS severi

218 effect is not secondary to medication use or comorbid medical illness.

219 and implicated in pathophysiology underlying comorbid medical illnesses.

220 of drugs for treatment of both seizures and comorbid memory impairments associated with epilepsy.

221 d treatment of most affected people who have comorbid mental and other drug use disorders.

222 health care costs and, when associated with comorbid mental health problems, it quadruples the costs

223 th ASD, 68 died (0.3%) (57 of 68 [83.8%] had comorbid mental/behavioral or neurologic disorders).

224 However, little is known about the effect of comorbid methamphetamine and tobacco use on human fetal

225 AE alone or influenza alone survived, 70% of comorbid mice died as a result of uncontrolled viral rep

226 is enhanced susceptibility, we established a comorbid model system in which mice with experimental au

227 SD 1.49) and 14 (88%) of the 16 patients had comorbid mood disorders, anxiety disorders, or both.

228 disorder (ADHD) - prevalent and often highly comorbid neurodevelopmental disorders - others have not

229 N: MCI diagnosis usually was associated with comorbid neuropathologies; less than one-quarter of MCI

230 eutic development that could improve several comorbid neuropsychiatric conditions.

231 exacerbated with the presence of secondary (comorbid) neuropsychiatric diagnoses, lower verbal and p

232 ants with TS (29.8%) may be accounted for by comorbid OCD (OR, 3.7; 95% CI, 2.9-4.8; P < .001).

233 ; 95% CI, 0.3-0.9; P = .02) independent from comorbid OCD and ADHD; however, high rates of mood disor

234 this study was to investigate the effect of comorbid ODD on cerebral volume and cortical thickness i

235 Remarkably, the impact of comorbid oppositional defiant disorder (ODD) (comorbidit

236 red with visits for patients with PAD alone, comorbid PAD and CAD were more likely to be prescribed a

237 riability in brain structure or to represent comorbid pathologic features rather than early emerging

238 mixed AD neuropathologic changes (ADNC; >/=1 comorbid pathology) were more frequent than "pure" ADNC

239 increasingly serve a population of multiply comorbid patients in an environment defined by organ sca

240 Comorbid patients presented decreased activity in the ci

241 Comorbid patients showed an abnormal frontal-greater-tha

242 y durable repair with low morbidity, even in comorbid patients with large defects.

243 2.29]), paranoid subtype (1.24 [1.13-1.37]), comorbid personality disorder (1.24 [1.11-1.39]), psycho

244 Having a comorbid personality or substance use disorder also incr

245 We searched for comorbid phenotypes with motion sickness, confirming ass

246 ted changes in connectivity in patients with comorbid posttraumatic stress disorder and MDD.

247 ly applicable to patients with AD, given the comorbid presentation of depression and cognitive defici

248 lus behavioral disorders was the most common comorbid profile among males, affecting 1 in 6.

249 Intersecting screens across comorbid proteinopathies thus reveal shared mechanisms a

250 ing the association between migraine and the comorbid psychiatric conditions and to determine the mos

251 amined the possible mediating role of common comorbid psychiatric conditions in this association.

252 ence diagnoses; 1 in 5 (20.1%) had 2 or more comorbid psychiatric diagnoses.

253 oup analysis, and excluded participants with comorbid psychiatric diagnoses.

254 history of hazardous alcohol use, and 57% a comorbid psychiatric diagnosis.

255 t influence results, nor did the presence of comorbid psychiatric disorders (all p>0.5).

256 of mental health, substance dependence, and comorbid psychiatric disorders in young transgender wome

257 adipokine concentrations, eating behaviors, comorbid psychiatric disorders or lifestyle factors.

258 iew of the link between migraine and several comorbid psychiatric disorders, including depression, an

259 Alcohol-dependent individuals with no comorbid psychiatric, medical, or drug abuse disorders w

260 were downregulated in cases with symptoms of comorbid PTSD and depression and consistently in cases w

261 nt of PPM1F, rs17759843, was associated with comorbid PTSD and depression and with PPM1F expression i

262 umans and found it to be lower in cases with comorbid PTSD and depression.

263 methods implies that biologically meaningful comorbid relations may be less frequent than earlier pai

264 , 2.45-17.51), of which 28% was explained by comorbid renal failure and hazardous alcohol use.

265 e more often younger, smokers, and with less comorbid risk factors compared with those with lower WBC

266 In addition to known demographic and comorbid risk factors for AKI, patients with longer AKI

267 Despite more comorbid risk factors in women, their nonculprit plaques

268 Comorbid-specific HALE was estimated from 20 years of ag

269 Since the comorbid spectrum of BBS phenotypes spans diabetes, rena

270 Understanding mPFC pathophysiology in this comorbid state has been hampered by the dearth of releva

271 or to understand the neural underpinnings of comorbid stress disorders and drug use by determining wh

272 Targeting of comorbid substance misuse would have particular effect o

273 s a novel treatment possibility for reducing comorbid SUDs in stress disorders.

274 lts suggest a higher benefit of hyperoxia in comorbid swine due to an increased susceptibility to hem

275 tent profile analysis identified profiles of comorbid symptoms, and multivariable multinomial logisti

276 nificantly associated with increased risk of comorbid symptoms.

277 ntervention strategies for this debilitating comorbid syndrome.

278 actors delineated a distinct biosignature in comorbid TBDM in this cohort.

279 lthough alcoholism and depression are highly comorbid, treatment options that take this into account

280 athology as evidenced by diseases exhibiting comorbid visceral and psychiatric symptoms.

281 V therapies, and the increased prevalence of comorbid, well-established risk factors for cancer, such

282 ed in several psychiatric disorders that are comorbid with alcoholism and involve amygdala dysfunctio

283 nction of peripheral perfusion and are often comorbid with altered cardiovascular responses to muscle

284 m in several rare monogenic syndromes highly comorbid with autism - fragile X and tuberous sclerosis

285 opioids, and previous history of drug abuse comorbid with chronic pain promotes higher rates of opio

286 ism for the attention and memory impairments comorbid with chronic pain.

287 Posttraumatic stress disorder is often comorbid with MDD, and symptoms of both disorders can be

288 ults provide evidence that hypercalcaemia is comorbid with migraine headache diagnoses, and that gene

289 Conditions recognised to be comorbid with migraine include asthma, anxiety, depressi

290 ait associated with eating disorders that is comorbid with mood and substance use disorders.

291 Cardiovascular dysfunction is highly comorbid with mood disorders, such as anxiety and depres

292 Depression, a condition commonly comorbid with multiple sclerosis (MS), is associated mor

293 he mPFC-specific cognitive deficits that are comorbid with neuropathic pain.SIGNIFICANCE STATEMENT Th

294 y disorder (ADHD) has been often found to be comorbid with other disorders, including anxiety, depres

295 imaging, we compared human infants with PCE comorbid with other drugs (such as nicotine, alcohol, ma

296 irror movements phenotypes, a phenotype also comorbid with PD.

297 ld traumatic brain injury, which is commonly comorbid with PTSD.

298 tting violent acts, particularly if they are comorbid with substance misuse.

299 bsessive compulsive disorder (OCD) are often comorbid with the overlap based on compulsive behaviors.

300 der (MDD) and nicotine dependence are highly comorbid, with studies showing that ~50% of individuals