ライフサイエンスコーパス: conservative

1 ting mixture toxicity, while CA was the most conservative.

2 bcellular locations and their evolution more conservative.

3 gests that the reported estimates are likely conservative.

4 y adapt their behavior to be either hasty or conservative.

5 ver to the pertuzumab group and is therefore conservative.

6 NS evolution appears to have been remarkably conservative.

7 cal-specific approach are reasonable, albeit conservative.

8 stic and Bayes logistic (BL) regressions are conservative.

9 h fluid-liberal strategy versus 50% in fluid-conservative.

10 (FL) regression performs well or is slightly conservative.

11 As an upper limit, the estimate is conservative.

12 2% of comparisons), but that were often more conservative (63%-76% of comparisons) and had lower unce

13 We have demonstrated the importance of conservative adjustment of q-value, particularly in the

14 We proposed a statistical method for the conservative adjustment of q-value.

15 for the most deadly cancers, and that a less conservative alpha may be necessary.

16 ution of peptide residues p2C and p5M to the conservative alpha-aminobutyric acid and norleucine, res

17 gh the switches between the codons result in conservative amino acid substitutions.

18 However, even in our most conservative analysis we find a fraction of more than 0.

19 In particular, to allow conservative and effective use of antibiotics clinical s

20 n, though computationally trivial, is overly conservative and fails to account for linkage disequilib

21 n 8 mm Hg experienced similar mortality with conservative and liberal fluid management (18% vs 18%; p

22 ence into evaluation and treatment, initiate conservative and medical therapy, and refer to specialis

23 ressures by computing %GC-corrected rates of conservative and radical nonsynonymous nucleotide substi

24 ideology by detailing conditions under which conservatives and liberals are better suited to engage i

25 climate change, so that across these studies conservatives and liberals were nearly equally likely to

26 /wide excision with partial skin resection ("conservative") and 38 underwent resection of all or near

27 could result from fundamental differences in conservatives' and liberals' temporal focus.

28 Conservatives appear more skeptical about climate change

29 In the conservative approach (restricted to using variants with

30 ors should be taken into account, but a more conservative approach can be considered initially in som

31 rom our own experience and the literature, a conservative approach seems appropriate for providing PE

32 omized clinical trial evidence and support a conservative approach to PDA management.

33 e recent analyses have suggested that a more conservative approach to the management of DCIS without

34 l acuity was not compromised so we planned a conservative approach with close observation.

35 Intraorbital haematoma can be managed by conservative approach without any intervention if it doe

36 ly available human data sets, we show that a conservative approach, using stringent filtering is requ

37 d long-term prognosis with the adoption of a conservative approach.

38 resolution often produce misassemblies, and conservative approaches lead to unnecessary fragmentatio

39 Reasonable conservatives are in short supply and will not arrive to

40 Thus, conservatives are not only more likely to use stereotype

41 , we rely on this notion to demonstrate that conservatives are positively affected by past- but not b

42 ted hazard ratio for 90-day mortality in the conservative arm was 0.77 (95% CI, 0.40-1.50; P = 0.44)

43 and FA, the IA-predicted effects seem to be conservative as antagonism between the two stressors was

44 r work, we also calculated the loss with the conservative assumption that the contribution to product

45 Under the conservative assumption that the response of soil carbon

46 Under conservative assumptions about household income, our mod

47 Sensitivity analyses based on less conservative assumptions led to much higher estimates.

48 Even with conservative assumptions regarding the productive popula

49 each unit of C gain, and increasingly water-conservative at high ca , when photosystems are saturate

50 motion, we suggest the existence of a rapid conservative athermal mechanism, by which the arrested e

51 with increases in ICERs (up to 4.2-fold) in conservative base-case analysis.

52 cated that concentration addition provided a conservative basis for predicting ELS effects for the mi

53 Here I apply an extremely conservative Bayesian method to estimate the number of r

54 yptophan substitution (Y162W) appeared to be conservative, because the mutant protein retained a high

55 ing maternal effects (i.e., diversifying and conservative bet-hedging), are expected to evolve in res

56 ific domains they cite in discussing an anti-conservative bias raise issues that merit closer examina

57 , 202 participants) and were unresponsive to conservative care.

58 ments are more likely to be deleterious than conservative changes.

59 Conservative climate change projections indicate a 30-40

60 ted with methylation at age 7 or 17 (using a conservative correction for multiple testing of P < 1.03

61 A conservative cost-benefit analysis of EpxDialysis demons

62 Compared to the more conservative DBD of NRs, sequences of LBD were less cons

63 gency" signal that changes between hasty and conservative decision policies.

64 A conservative definition of a QFT-Plus-positive result yi

65 iated cells without proliferation, meeting a conservative definition of direct transdifferentiation.

66 if both TB1 and TB2 tested positive, using a conservative definition.

67 studies of novel combinations should employ conservative designs that incorporate pharmacodynamics/b

68 .8%, hence providing some support for a more conservative diagnostic approach.

69 tical homogeneity for psychology depend upon conservatives disclosing their political identity.

70 per-binding organic ligands showed a linear, conservative distribution with increasing salinity, illu

71 Telomeric MiDAS is a conservative DNA synthesis process, potentially mediated

72 n and reduced GFR in patients with diabetes, conservative dose selection and adjustment of antihyperg

73 This suggests that multiple mechanisms of conservative DSB repair may contribute to tumor suppress

74 ive species operate within the constraint of conservative ecological niches, or if niche shifts occur

75 decoctions had a higher functionalizing and conservative effect.

76 It opens up a promising avenue to convince conservatives effectively of the need to address climate

77 Here we confirm the conservative energy exchange between the electromagnetic

78 etal approach in risk evaluations may not be conservative enough for metal mixtures.

79 In 2010, the most conservative estimate of economic welfare losses due to

80 A conservative estimate of the annual costs of atopic derm

81 The conservative estimate of the minimum global VN volume is

82 ecadal timescales in this system, based on a conservative estimate of the rate at which seagrass can

83 These findings imply a conservative estimate of the size of the prokaryotic gen

84 A conservative estimate places a lower limit of 345 +/- 70

85 Our study, although a conservative estimate, suggests that by late century, fo

86 ese WM-containing regions may result in more conservative estimates of actual change.

87 hough this mobile monitoring method produces conservative estimates of leak rates and leak counts, it

88 With conservative estimates of relative target molecule abund

89 Given conservative estimates regarding DNA transcription rates

90 Our conservative estimates suggest that GBS is a leading con

91 a nonparametric method and has accurate and conservative estimation of FDR profile.

92 ference-of-means estimator, and we provide a conservative estimator of the asymptotic variance, which

93 Conservative fluid management decreases mortality for ac

94 a multicenter randomized controlled trial of conservative fluid management in acute respiratory distr

95 In acute respiratory distress syndrome, conservative fluid management increases ventilator-free

96 ute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulte

97 FACTT Lite is an alternative to FACTT Conservative for fluid management in Acute Respiratory D

98 the Bonferroni and FDR are exceedingly over-conservative for rare variants association studies.

99 rametric statistical methods are shown to be conservative for voxelwise inference and invalid for clu

100 xplicitly modeled by Newtonian dynamics of a conservative force field plus two asymmetrical dissipati

101 or transmit through each other, are found in conservative, fully integrable systems.

102 Plant species with resource-conservative functional traits (low specific leaf area,

103 mm Hg [interquartile range, 88-116]) vs the conservative group (median Pao2, 87 mm Hg [interquartile

104 We found that 26.5% of patients in the conservative group needed appendectomy within 1 year, re

105 The radical group (vs the conservative group) more often had multifocal disease (8

106 lobin saturation (Spo2) between 94% and 98% (conservative group) or, according to standard ICU practi

107 An evolutionarily conservative group, benthic foraminifera often comprise

108 % in the laparoscopy group versus 50% in the conservative group, P = 0.002.

109 laparoscopy group versus 5 days (3-8) in the conservative group, P = 0.105.

110 roscopy group and in 4 (13%) patients in the conservative group.

111 e-specific survival (DSS) for radical versus conservative groups was 86% versus 46% (P < 0.01), respe

112 ce and distant metastasis for radical versus conservative groups were 23% versus 76% (P < 0.01) and 1

113 This finding suggests that conservative guidelines regarding the maximum caffeine i

114 Only states with a conservative H-cluster geometry featuring a muCO ligand

115 calculated toxicity thresholds may be overly conservative (here by >100-fold) with respect to natural

116 trand exchange protein in yeast required for conservative HR.

117 Second, we report that more conservative hypoxia regimens, such as continuous normob

118 l, 0.05-0.92; P = .009) than those receiving conservative/immunosuppressive therapy.

119 C export to riverine systems, in a way to be conservative in a mass balance.

120 ution volume ratiohigh = 1.20) that are more conservative in defining Pittsburgh compound-B positron

121 Sperm characters are very conservative in some groups (Heteroptera, Odonata) but h

122 Second, clustroids of conservative in-clade clusters are organized into seed g

123 n distributions predicted by the model for a conservative (inert) tracer.

124 more clearly define conditions under which a conservative interpretation can be used to minimize nonr

125 A conservative interpretation of QFT-Plus eliminated nearl

126 Recently, autophagy, a highly conservative intracellular recycling system, has shown t

127 Conservative intravenous fluid administration and antibi

128 (MI), and rehospitalization compared with a conservative invasive approach in acute coronary syndrom

129 Moreover, the most conservative ion, chloride, increased >500% in shrinking

130 Near-chemostatic relationships between conservative ions and discharge implied that groundwater

131 To provide a conservative landscape of transcripts differentially exp

132 -corrected significance level is known to be conservative, leading to insufficient statistical power

133 demonstrated that DNA synthesis during HR is conservative, less processive, and more mutagenic than r

134 Relative to conservatives, liberals more frequently used positive em

135 in a highly admixed rural population with a conservative lifestyle.

136 ion is highly admixed and has a cohesive and conservative lifestyle.

137 otherapy combined with high-intensity versus conservative LT for primary mUCB.

138 r in the high-intensity LT group than in the conservative LT group (14.92 [interquartile range, 9.82

139 elivered to the bladder were included in the conservative LT group.

140 tients with mUCB received high-intensity and conservative LT, respectively.

141 with mUCB treated with high-intensity versus conservative LT.

142 patients who received high-intensity versus conservative LT.

143 om extensive agriculture to intensive, water-conservative maize cultivation that was motivated by a d

144 compared with endoscopic treatment (65%) and conservative management (97%) (adjusted odds ratio, 24.9

145 The patient elected for conservative management and at 3-month follow-up her sym

146 ients with cancer who do not respond to more conservative management and who continue to experience d

147 ervatively and ideally in combination with a conservative management approach for low-risk disease.

148 rhinosinusitis not controlled by appropriate conservative management for 4 months, and difficult-to-t

149 ite successful sinus surgery and appropriate conservative management for at least 1 year.

150 es-particularly when combined with increased conservative management for low-risk cases-is uncertain.

151 NH) is a common benign liver tumor for which conservative management is indicated.

152 e sensitivity analyses, suggestive that more conservative management of abnormal preoperative interna

153 On the basis of the retrospective studies, conservative management of appendiceal abscess is recomm

154 As such, clinicians have tended toward conservative management strategies; however, the benefit

155 prognosis are older age, cancer etiology and conservative management.

156 s when underlying pathology is identified or conservative measures are ineffective.

157 s been a paradigm shift in the management by conservative measures, especially, when surgery is not u

158 eyes with recurrent tumor can be salvaged by conservative methods.

159 Conservative minimum ice volume estimates show that waxi

160 stablished compound heterozygosity for a non-conservative missense change affecting a key residue par

161 than 20 cases when untreated or treated with conservative modalities.

162 illion people needing but not receiving RRT; conservative model) and Africa (432,000 people; conserva

163 servative model) and Africa (432,000 people; conservative model).

164 hysiologically inactive even with relatively conservative modifications, highlighting the importance

165 ns that may be considered oversimplistic and conservative; most notably the unit refill rate.

166 interquartile range 13%-88%), which is above conservative MRSE estimates.

167 Even conservative mutagenesis at these sites (E692D/R701K/T70

168 monitor HR-mediated gene conversion and non-conservative mutation events.

169 e a substrate-bound, occluded state, and non-conservative mutation of Tyr130 reduces the stability of

170 After characterizing the size or charge conservative mutations Arg-126-Gln, Asp-49-Asn, and Arg-

171 tocurrents generated from ChR2 proteins with conservative mutations at these positions demonstrated t

172 incidence of radical mutations compared with conservative mutations in elderly subjects' vaccine resp

173 r binding pocket identification, assisted by conservative mutations in the pocket, we engineered a no

174 %] women) received conventional (n = 218) or conservative (n = 216) oxygen therapy and were included

175 tainty will be reduced by incorporating this conservative nature of the morphological response to E-[

176 d diffusion more strongly within liberal and conservative networks, and less between them.

177 ith TMJDs should be an important part of the conservative, noninvasive care of individuals diagnosed

178 The effects of conservative, nonionizable substitutions of the TL histi

179 Unlike other non-conservative nonlinear arrangements where self-trapped s

180 ed" into abbreviated laparotomy using "rapid conservative operative techniques." Subsequent "explorat

181 ncer, breast conservation surgery (BCS) is a conservative option for women and involves removing the

182 These methods are conservative or generate many false-positive results, pa

183 These choices become more conservative over time.

184 nopy evapotranspiration (ET) was reasonably 'conservative' over the studied LAI range 0.5-7.0 m(2) m(

185 Twenty-five patients in the conservative oxygen therapy group (11.6%) and 44 in the

186 Occurrences were lower in the conservative oxygen therapy group for new shock episode

187 Conservative oxygen therapy is aimed at the prevention o

188 clinical outcomes, but the causal impact of conservative oxygenation is still to be determined.

189 Our study supports the feasibility of a conservative oxygenation strategy in patients receiving

190 24 hours were randomly allocated to either a conservative oxygenation strategy with target oxygen sat

191 cal outcomes of a two-step implementation of conservative oxygenation targets in the ICU.

192 Stepwise implementation of conservative oxygenation targets was feasible, effective

193 e and after stepwise implementation study of conservative oxygenation targets, between July 2011 and

194 We used a conservative p value of less than 0.01 to indicate stati

195 amino-terminus of a carrier protein and even conservative peptide amino acid substitutions resulted i

196 ce levels, the glider adopts an increasingly conservative policy as turbulence levels increase, quant

197 f metagenomics (e.g. biodiversity analyses), conservative pooled assembly is advantageous for annotat

198 Objective: To assess whether a conservative protocol for oxygen supplementation could i

199 ICU length of stay of 72 hours or longer, a conservative protocol for oxygen therapy vs conventional

200 Current evidence recommends a conservative (provisional) approach when treating the si

201 Conservative reanalyses under consideration of potential

202 These estimates are conservative; removal by clams in Connecticut, oysters a

203 t7 C2A domains arise in part from apparently conservative residue substitutions, showing how striking

204 each amino acid residue for alanine or more conservative residues, glutamine or asparagine, in the G

205 political divide that separated liberal and conservative respondents' attitudes toward and behavior

206 f treatment (aortic valve replacement versus conservative), rest GLS <|9|% (hazard ratio, 2.18; P=0.0

207 etwork, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balan

208 oncordance <22%), while CBA methods provided conservative results but required large sample sizes for

209 ylobacter, Cryptosporidium, and rotavirus as conservative risk proxies for infections via bacteria, p

210 turally diverse leaf networks, we found that conservative rules described the progression of hydrauli

211 ations and negative publicity by embracing a conservative/safe approach-seemingly ignoring research o

212 change scenarios, we predict under the least conservative scenario (+3.7 degrees C) that 25% of cactu

213 ombined as independent risk factors and in a conservative scenario in which we assumed full overlap o

214 In the conservative scenario, about 4.5% (626 900 new cases) of

215 8 participants, of whom 2,392 remained after conservative screening for previous depressive symptoms.

216 suitable for pH measurements in seawater and conservative seawater-derived brines at salinities (S) b

217 Nature uses a limited, conservative set of amino acids to synthesize proteins.

218 t mendelian randomization methods and a more conservative set of instruments.

219 Both liberals and conservatives show partisan bias that often worsens with

220 our results suggest that MoGsk1, as a highly conservative signal modulator, dictates growth, conidiat

221 stantial (8.3 +/- 0.8 per cent from our most conservative simulation), variable linear polarization o

222 We show that this is likely due to the conservative species definition rather than to any ecolo

223 rategy, with higher defense in more resource-conservative species, although there is little support f

224 ng it, and wrongly projects the U.S. liberal-conservative spectrum to the whole field of social psych

225 rts have suggested more personalized or more conservative strategies to improve benefit-risk tradeoff

226 g or less experienced lower mortality with a conservative strategy (17% vs 36%; p = 0.005).

227 ts with desmoid-type fibromatosis, the EpSSG conservative strategy did not compromise outcomes and co

228 Among the variants identified, one conservative substitution (F45betaY) was most prevalent.

229 substitution had no significant effect, non-conservative substitution of either residue (D43C or T47

230 tial interaction with an aspartate/histidine conservative substitution on the BC loop of BET bromodom

231 mutagenesis throughout the protein involving conservative substitutions of hydrophobic residues, key

232 mechanism of enzyme inhibition at the highly conservative substrate-recognition pocket.

233 worse survival outcomes compared with breast conservative surgery (BCS) (adjusted hazard ratio [adjHR

234 urce-acquisitive syndromes to slow, resource-conservative syndromes.

235 nd decay of modulationally unstable waves in conservative systems.

236 living fossils", supposedly slowly evolving, conservative taxa, with a long fossil record back to the

237 Conservatives tend to focus more on the past than do lib

238 fitting latent variable, yielding robust and conservative tests.

239 A conservative therapeutic approach was preferred and the

240 Acupuncture is a minimally-invasive and conservative therapeutic option, and while rooted in a c

241 Fluid-conservative therapy has also increased ventilator-free

242 ther facility, and she did not to respond to conservative therapy.

243 predict spontaneous remission, thus favoring conservative therapy.

244 change their glide plane only by a slow, non-conservative, thermally activated motion, we suggest the

245 However, RIS subjects showed, at a less conservative threshold, lower diffusivities than RRMS pa

246 Rice morphological development is conservative to carbon acquisition.

247 DNA does not follow the same dynamics as the conservative tracer and necessitates a more stochastic f

248 uifer is complex and does not correlate with conservative tracer transport.

249 s characterized on the basis of the bromide (conservative tracer) breakthrough time at the port.

250 ure the residence time of eDNA compared to a conservative tracer, and we model the transport of eDNA

251 The depth profiles of As and SO4 and the conservative tracers Cl/Br, delta(18)O, and delta(2)H sh

252 receive effective CPAP therapy (n = 151) or conservative treatment (n = 156) for 3 months.

253 d to either laparoscopic surgery (n = 30) or conservative treatment (n = 30).

254 issue Sarcoma Study Group (EpSSG) proposed a conservative treatment algorithm-consisting of an initia

255 could increase the likelihood of successful conservative treatment and hence reduce the need for sur

256 se of matched adolescent controls undergoing conservative treatment and of adult controls undergoing

257 dren includes ultrasonographic follow-up and conservative treatment and rarely requires surgical inte

258 All of the cases failed to respond to conservative treatment and were successfully managed wit

259 ongoing debate on the merits of surgical and conservative treatment for acute appendicitis.

260 Clinical Question: Does local conservative treatment for cervical intraepithelial neop

261 High recurrence rates of 50-80% with conservative treatment in some sub-types warrants radica

262 The ICTUS (Invasive Versus Conservative Treatment in Unstable Coronary Syndromes) t

263 While conservative treatment is recommended in asymptomatic ca

264 effectiveness and safety of surgical versus conservative treatment of acute appendicitis.

265 al meniscectomy (APM) offers no benefit over conservative treatment of patients with a degenerative m

266 , which varies from immediate orchiectomy to conservative treatment resulting in testicle atrophy.

267 Moreover, disease resolution with conservative treatment strengthens the approach to limit

268 Conservative treatment was associated with an acceptable

269 Conservative treatment was planned but both of them succ

270 ions and fewer additional interventions than conservative treatment with comparable hospital stay.

271 (CTO PCI), and 154 patients were assigned to conservative treatment without PCI of the CTO (no CTO PC

272 men about treatment options, in particular, conservative treatment, might help mitigate long-term re

273 he bolus, the patient was submitted to a new conservative treatment, the "Nitro-Push Blind Technique"

274 In those not responding to conservative treatment, the approach needs to be tailore

275 e rate of up to 30% has been found following conservative treatment.

276 demonstrated rapid clinical improvement with conservative treatment.

277 mptoms, and daytime sleepiness compared with conservative treatment.

278 ith substantial faecal incontinence for whom conservative treatments (such as dietary changes and pel

279 lytic therapy for CRAO is warranted and that conservative treatments are futile and may be harmful.

280 Long-term benefits of conservative treatments in adolescents are known to be m

281 lumbar disk degeneration and unresponsive to conservative treatments into 2 groups.

282 and children, and are more likely to suggest conservative treatments such as occlusion and minus lens

283 : Compared with D1 lymphadenectomy (the most conservative type of lymph node dissection), D2 lymphade

284 The remaining part, coming from either non-conservative (unique) or rapidly evolving proteins, from

285 en age groups, with adolescents showing more conservative updating.

286 me learning model, but adolescents show more conservative updating.

287 We observe high pattern quality, conservative usage of reagents, micrometer precision of

288 ent utilisation of each material and enables conservative use of hard-to-obtain materials.

289 this work we test this result with much more conservative variants in which individual Tyr residues i

290 entage time spent with SpO2 less than 88% in conservative versus liberal arm was 1% versus 0.3% (P =

291 age time spent with SpO2 greater than 98% in conservative versus liberal arm was 4% versus 22% (P < 0

292 0.26 [0.25-0.28] vs. 0.36 [0.34-0.39) in the conservative versus liberal oxygenation arm were signifi

293 our experience and focused on the impact of conservative versus radical resections.

294 viewpoints with little evidence, promotes a conservative viewpoint without defining it, and wrongly

295 In the present research, we found that conservatives were also more likely to negatively evalua

296 n control the type I error rate and is a bit conservative when compared to the permutation method.

297 ermore, the derived P-values are known to be conservative when sample size is small, especially for t

298 ction for multiple tests, which often is too conservative when the number of markers is extremely lar

299 fluid-liberal strategy versus 18% with fluid-conservative, whereas mortality in subphenotype 2 was 40

300 f the synthetic yeast genome Sc2.0 is highly conservative with respect to gene content, the deletion