ライフサイエンスコーパス: coronary occlusion

1 geted at the underlying disease (e.g., acute coronary occlusion).

2 and angina pectoris during the same 1-minute coronary occlusion.

3 extent of myocardial necrosis consequent to coronary occlusion.

4 lead to larger infarcts caused by persistent coronary occlusion.

5 ection of the onset of ischemia during acute coronary occlusion.

6 endent determinant of infarct size following coronary occlusion.

7 pate in the arrhythmogenic response to acute coronary occlusion.

8 ise healthy men even in the absence of acute coronary occlusion.

9 ired with 13N-ammonia at baseline and during coronary occlusion.

10 as was sudden death due to acute thrombotic coronary occlusion.

11 ct ultimate infarct size (IS) at the time of coronary occlusion.

12 cur during reperfusion of a limited-duration coronary occlusion.

13 different stenoses using ATP, adenosine, and coronary occlusion.

14 l axis, as observed with proximal circumflex coronary occlusion.

15 dogs undergoing an AIP 201 injection during coronary occlusion.

16 single left heart injection performed during coronary occlusion.

17 es isolated from hearts subjected to chronic coronary occlusion.

18 perfusion in dogs with chronic single-vessel coronary occlusion.

19 0 micrograms/kg) 10 minutes before the first coronary occlusion.

20 ersibly injured myocardium after 24 hours of coronary occlusion.

21 in the jeopardized zone, and the duration of coronary occlusion.

22 LO) myocardial phagocytes after experimental coronary occlusion.

23 etector computed tomography during the index coronary occlusion.

24 primary outcome was the finding of a recent coronary occlusion.

25 rgoing angioplasty balloon-induced transient coronary occlusion.

26 asurement is modestly predictive of a recent coronary occlusion.

27 rotic coronary plaque, resulting in subtotal coronary occlusion.

28 e independent predictive factors of a recent coronary occlusion.

29 the optimum cutoff for identifying a recent coronary occlusion.

30 e a sensitive/specific marker for thrombotic coronary occlusion.

31 Src (p-cSrc) post-MI using a canine model of coronary occlusion.

32 etector computed tomography during the index coronary occlusion.

33 diomyopathy (I/RC) arising from daily, brief coronary occlusion.

34 ague-Dawley rats were subjected to permanent coronary occlusion.

35 dministered at the time of reperfusion after coronary occlusion.

36 al infarction in a porcine model of complete coronary occlusion.

37 (PDGF)-AB decreases myocardial injury after coronary occlusion.

38 h STEMI and mapped the location of the acute coronary occlusion.

39 restoration of cardiac function after acute coronary occlusion.

40 ors are involved, then the benefits of brief coronary occlusion (1) should be manifested systemically

41 In protocol 1, dogs received 10 minutes of coronary occlusion + 10 minutes of reflow or a comparabl

42 clusion was preceded by brief I/R (10-minute coronary occlusion/10-minute reperfusion) versus 20-minu

43 On repetitive coronary occlusion, 14 of 25 neurons demonstrated tachyp

44 us pigs underwent a sequence of ten 2-minute coronary occlusion/2-minute reperfusion cycles and then

45 Four weeks after coronary occlusion, 36 rats were randomized to IGF-1 (3

46 te PC (one, three, or six cycles of 4-minute coronary occlusion [4'O]/4-minute reperfusion [4'R]; fou

47 otocol consisting of three days of six 4-min coronary occlusion/4-min reperfusion cycles.

48 tioned 24 h earlier with six cycles of 4-min coronary occlusion/4-min reperfusion exhibited a signifi

49 schemic PC (induced with six cycles of 4-min coronary occlusion/4-min reperfusion), immunoprecipitati

50 A sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles (ischemic

51 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

52 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

53 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

54 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

55 were subjected to ischemic PC (six 4-minute coronary occlusion/4-minute reperfusion cycles) and, 24

56 its were subjected to a sequence of 4-minute coronary occlusion/4-minute reperfusion cycles, myocardi

57 In mice preconditioned with six 4-minute coronary occlusion/4-minute reperfusion cycles, we found

58 A sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles, which el

59 cious rabbits underwent 6 cycles of 4-minute coronary occlusion/4-minute reperfusion.

60 e preconditioned with six cycles of 4-minute coronary occlusion/4-minute reperfusion.

61 Ischemic PC (six cycles of 4-min coronary occlusions/4-min reperfusions) resulted in a ra

62 Female rats underwent a 90-minute coronary occlusion; 4 hours after reperfusion, they rece

63 ized rabbits received 5 minutes of transient coronary occlusion, 5 minutes of transient bilateral car

64 trend <0.001) but not reaching the level of coronary occlusion (6.35+/-2.26).

65 usly in anesthetized, open-chest dogs before coronary occlusion (90 minutes) and reperfusion (120 min

66 In conscious swine subjected to a sustained coronary occlusion, a PC protocol that induces powerful

67 During the first 5 to 15 min of coronary occlusion, a slight decrease in the concentrati

68 t administration of 99mTc-tetrofosmin during coronary occlusion accurately delineates the flow hetero

69 ion units (TPUs) and pH were measured before coronary occlusion, after occlusion, and after direct ex

70 en A3tg mice were subjected to 30 minutes of coronary occlusion and 24 hours of reperfusion, infarct

71 arct size in mice subjected to 30 minutes of coronary occlusion and 24 hours of reperfusion.

72 Conscious rabbits underwent a 30-minute coronary occlusion and 3 days of reperfusion.

73 ated rabbits (group I) underwent a 30-minute coronary occlusion and 3 days of reperfusion.

74 CaCl2 or saline before undergoing 1 hour of coronary occlusion and 4 hours of reperfusion (protocol

75 dence that ischemic PC (6 cycles of 4-minute coronary occlusion and 4-minute reperfusion) induces sel

76 mongrel dogs were subjected to 15 minutes of coronary occlusion and 5 hours of reperfusion.

77 to microsphere-determined blood flow during coronary occlusion and at tracer injection.

78 e stimuli, that afferent spinal responses to coronary occlusion and bradykinin are different.

79 e surviving portion of the wall 8 days after coronary occlusion and cardiac failure in rats.

80 We used a porcine model of chronic coronary occlusion and collateral development to evaluat

81 during this period of time, after prolonged coronary occlusion and complete reflow, the rate of myoc

82 raphy/magnetic resonance imaging after acute coronary occlusion and interventional reperfusion.

83 of perfusion abnormalities that occur during coronary occlusion and may facilitate estimation of the

84 howing contrast enhancement on 3D MCE during coronary occlusion and postmortem risk volume (y = 1.2x

85 ntrast echocardiography were measured during coronary occlusion and reflow, using fundamental and har

86 rovascular and myocardial injury well beyond coronary occlusion and reflow.

87 The perfusion defect sizes during coronary occlusion and reperfusion also correlated close

88 finity (DuPont) at baseline and during brief coronary occlusion and reperfusion and were analyzed wit

89 Ischaemic preconditioning with brief coronary occlusion and reperfusion before a sustained pe

90 F deficiency were observed in vivo following coronary occlusion and reperfusion in Mif-/- mice.

91 ium where inflammation was induced by either coronary occlusion and reperfusion or tumor necrosis fac

92 the clinical scenario in which intermittent coronary occlusion and reperfusion superimposed on a cri

93 Three hours of coronary occlusion and reperfusion were each produced in

94 meters provide estimates of RA and IA during coronary occlusion and reperfusion.

95 risk area (RA) and infarct area (IA) during coronary occlusion and reperfusion.

96 deduced that myocardial infarction is due to coronary occlusion and that subsequent death needs no ot

97 However, a 5-min coronary occlusion and the resulting ischemia do not alt

98 ld be produced in a porcine model of chronic coronary occlusion and to assess whether the adaptations

99 in L-NA-treated rabbits the sequence of six coronary occlusions and reperfusions performed on day 1

100 assessed for myocardial perfusion deficits, coronary occlusion, and abnormal myocardial wall motion.

101 fluorescent microspheres at baseline, during coronary occlusion, and at 5, 30, 90, and 180 min during

102 hyperemia, the size of the risk area during coronary occlusion, and the extent of myocardial salvage

103 hyperemia, the size of the risk area during coronary occlusion, and the extent of myocardial salvage

104 baseline; at reperfusion after 15 minutes of coronary occlusion; and at 30 minutes, 60 minutes, and 1

105 unded by acute reperfusion after a period of coronary occlusion are active areas of research.

106 ent necrosis could be identified early after coronary occlusion as having the lowest microvascular fl

107 In the sham or anti-VEGF groups, coronary occlusion at the end of the protocol induced ma

108 as injected before a brief (6 min) period of coronary occlusion at the following times: 15 min (n = 2

109 Thus, rats were subjected to a 90-min coronary occlusion; at 4 h after reperfusion, CSCs were

110 artially restored the neuronal activation to coronary occlusion but not to bradykinin.

111 ents cardiac dysfunction and ischemia due to coronary occlusion by tightening the link between cardia

112 nfarct size was assessed at 24 h after acute coronary occlusion by triphenyltetrazolium chloride (TTC

113 aration of proteins from hearts subjected to coronary occlusion by two-dimensional electrophoresis an

114 decreases in coronary flow or repeated brief coronary occlusions can be followed by proportionate rev

115 te study of LV remodeling, after a 60-minute coronary occlusion, cardiac magnetic resonance imaging r

116 In pigs, coronary occlusion caused a 59 +/- 26% decrease in PCIR

117 Chronic coronary occlusion (CCO) impairs endothelial function of

118 After prolonged coronary occlusion, contrast-enhanced MRI identifies myo

119 The presence of a concomitant chronic total coronary occlusion (CTO) and a large collateral contribu

120 nificant coronary disease have chronic total coronary occlusion (CTO), which is associated with long-

121 functional in the RI group because complete coronary occlusion did not induce any untoward effects o

122 In 31 open-chest dogs with acute coronary occlusion, dipyridamole (approximately 0.56 mg/

123 on period (baseline 2) and a during a second coronary occlusion during bypass anastomosis (occlusion

124 aemic postconditioning uses repetitive brief coronary occlusion during early reperfusion of myocardia

125 scious pigs underwent a sequence of 10 2-min coronary occlusions, each separated by 2 min of reperfus

126 ing), rabbits were subjected to six 4-minute coronary occlusions, each separated by 4-minute reperfus

127 he size of the infarcts produced by a 30-min coronary occlusion followed by 24 h of reperfusion was r

128 in rats was produced by using 30 minutes of coronary occlusion followed by 24 hours reperfusion.

129 on), conscious rabbits underwent a 30-minute coronary occlusion followed by 3 days of reperfusion.

130 Conscious rabbits underwent a 30-minute coronary occlusion followed by 3 days of reperfusion.

131 tion), rabbits were subjected to a 30-minute coronary occlusion followed by 3 days of reperfusion.

132 groups of pigs were subjected to a 40-minute coronary occlusion followed by 3 days of reperfusion.

133 mL/kg QW7437 in 14 dogs who underwent 3-hour coronary occlusion followed by 3-hour reperfusion.

134 Rats underwent a 90-minute coronary occlusion followed by 35 days of reperfusion.

135 istration of SDF-1alpha before 30 minutes of coronary occlusion followed by 4 hours of reperfusion de

136 rdial infarction was produced by a 30-minute coronary occlusion followed by 4 hours of reperfusion.

137 low coronary flow (protocol 1) and transient coronary occlusion followed by reflow (protocol 2).

138 Wild-type (WT) mice underwent a 30-minute coronary occlusion followed by reperfusion and received

139 open-chest dogs, which then underwent 2 h of coronary occlusion followed by reperfusion through the s

140 Fisher rats were subjected to 60 minutes of coronary occlusion followed by reperfusion.

141 anesthetized dogs underwent 3 to 6 hours of coronary occlusion followed by reperfusion.

142 Pigs underwent a 90-minute coronary occlusion followed by reperfusion.

143 nd MCP-1-null mice underwent daily 15-minute coronary occlusions followed by reperfusion.

144 nt 90 or 180 min of left anterior descending coronary occlusion, followed by 180 min of reperfusion.

145 90-min closed-chest left anterior descending coronary occlusion, followed by reflow.

146 derwent a 90-minute left anterior descending coronary occlusion, followed by reperfusion.

147 were assessed serially in dogs subjected to coronary occlusion for 45 min, 90 min, or permanently.

148 Total coronary occlusion frequently occurs in the absence of a

149 ed to collect data before, during, and after coronary occlusion from which percent systolic shortenin

150 r example, at matched ESVs before and during coronary occlusion, FRP was -1.1+/-1.1 (+/-SD) mm Hg bef

151 39 patients with successful angioplasty of a coronary occlusion (Group 1) and compared the frequency

152 ollBF were measured in 18 dogs: at 6 h after coronary occlusion (Group 1, n = 6), and during 40 micro

153 oronary occlusion or after 10 min of a fixed coronary occlusion (Group 3).

154 Thus, a series of ten 2-minute coronary occlusions had a profound (approximately 80%) e

155 ral development after experimentally induced coronary occlusion; however, methods of bFGF delivery th

156 Multiple, short, regional coronary occlusions immediately after prolonged myocardi

157 3DE was performed before and 3 hours after coronary occlusion in 16 dogs.

158 and maintenance of function during complete coronary occlusion in 3 groups of animals: sham (receive

159 ared with the hyperemic response of complete coronary occlusion in 6 canines.

160 n system to detect ST-segment elevation from coronary occlusion in a porcine model of ST-segment elev

161 ent shifts associated with acute or subacute coronary occlusion in a porcine model.

162 rdiac troponin I can help to detect a recent coronary occlusion in out-of-hospital cardiac arrest.

163 GSTP gene also increased infarct size after coronary occlusion in situ.

164 Mechanisms of coronary occlusion in ST-elevation acute coronary syndro

165 of ischemia/reperfusion in a model of brief coronary occlusion in which no necrosis or inflammatory

166 r dysfunction was created by repetitive left coronary occlusions in 7 pigs (7 healthy pigs also inclu

167 ium-regulatory genes (after repetitive total coronary occlusions in swine) have given rise to the hyp

168 termine early predictive factors of a recent coronary occlusion (including cardiac troponin I) and th

169 It has been shown that repeated brief coronary occlusions increase myocardial resistance towar

170 Early metoprolol administration during acute coronary occlusion increases myocardial salvage.

171 d in conscious pigs that a sequence of brief coronary occlusions induces severe myocardial stunning,

172 However, treatment of acute coronary occlusion inevitably results in ischemia-reperf

173 stered to isolated hearts before a 30-minute coronary occlusion, infarct size (15.6 +/- 2.0% of the r

174 Acute coronary occlusion is a serious manifestation of coronar

175 uroprotections through cooling rapidity when coronary occlusion is complicated by cardiac arrest.

176 Acute coronary occlusion is the leading cause of death in the

177 Acute coronary occlusions leading to ST-segment elevation myoc

178 Acute coronary occlusions leading to STEMI tend to cluster in

179 that preserving the original ECM early after coronary occlusion lessens ventricular remodeling.

180 nt of microvascular obstruction during acute coronary occlusion may determine the eventual magnitude

181 This raises the question that repeated coronary occlusions may also result in tachyphylaxis, th

182 We hypothesized that in the setting of coronary occlusion, MCE should identify RA as a perfusio

183 e MRI scans followed by either 60 minutes of coronary occlusion (MI group, n=15) or thoracotomy witho

184 In a transient coronary occlusion model, perfusion defect size using th

185 ental analysis with the use of larger animal coronary occlusion models should help determine the futu

186 endent LCx arterioles isolated after chronic coronary occlusion, most likely because of effects on ec

187 transverse aortic constriction or permanent coronary occlusion (myocardial infarction [MI]).

188 After 60-min coronary occlusion, myocardial pH fell from 7.43 +/- 14

189 volume and pressure overload during an acute coronary occlusion (n = 10).

190 flow for 2 h (n = 8) or repeated 2-min total coronary occlusions (n = 6).

191 (n=11), coronary artery stenoses (n=2), and coronary occlusions (n=2).

192 us rabbits underwent a sequence of six 4-min coronary occlusion (O)/4-min reperfusion (R) cycles for

193 les at baseline (baseline 1), during a 5-min coronary occlusion (occlusion 1), after a 5-min reperfus

194 A coronary occlusion of a branch of the left anterior desc

195 of 53 mongrel dogs in an open chest model of coronary occlusion of various durations followed by repe

196 fter 10 min (Group 1) or 60 (Group 2) min of coronary occlusion or after 10 min of a fixed coronary o

197 Permanent coronary occlusion or high-dose steroid therapy signific

198 recorded during 60 s of anterior descending coronary occlusion or local epicardial application of br

199 nfarction without reperfusion (chronic 7-day coronary occlusion) or receiving post-I/R high-dose ster

200 early after reperfusion following prolonged coronary occlusion overestimates the degree of viability

201 e versus 0.2+/-1.2 mm Hg after 10 minutes of coronary occlusion (P<.05).

202 vs. 0.93 +/- 0.41 mm Hg.ml(-1) during acute coronary occlusion [p < 0.05] and 7.9 +/- 3.1 m.s(-2) be

203 .s(-2) before vs. 4.4 +/- 1.0 m.s(-2) during coronary occlusion [p < 0.05], respectively).

204 (LV) structure and function after permanent coronary occlusion (PCO) and the potential involvement o

205 d in an ambulatory porcine model, with acute coronary occlusion precipitated by stent thrombosis.

206 Coronary occlusion produced stunning of the anterolatera

207 To examine whether reversible coronary occlusion produces sustained changes in regiona

208 5,199 (3 mg/kg i.v.) before brief antecedent coronary occlusion (protocol 3).

209 est dogs were subjected to a 10-minute acute coronary occlusion (proximal left anterior descending co

210 its have demonstrated that a series of brief coronary occlusions renders the heart relatively resista

211 Coronary occlusion-reperfusion (20 min each) sequences w

212 ium (Mg) reduces free radicals after a brief coronary occlusion-reperfusion sequence.

213 r repetitive ischemia differs in response to coronary occlusion-reperfusion versus supply-demand isch

214 hmias similar to those observed during acute coronary occlusion/reperfusion in intact hearts.

215 rdioprotection, insofar as brief episodes of coronary occlusion/reperfusion preceding (ischemic preco

216 inhibition (GPI) on microvascular flow after coronary occlusion/reperfusion using quantitative myocar

217 nts undergoing CABG and from pigs undergoing coronary occlusion/reperfusion without (sham) and with R

218 ular flow and reduces the infarct area after coronary occlusion/reperfusion, independent of epicardia

219 One month after coronary occlusion/reperfusion, rats received an intraco

220 hyperenhancement of myocardium subjected to coronary occlusion/reperfusion.

221 sion) or placebo (PLA) before 60/180 minutes coronary occlusion/reperfusion.

222 Acute coronary occlusion results in a rapid decrease in forces

223 ultrasonography, which confirmed thrombotic coronary occlusion/ruptured plaque.

224 kg) was infused 5 minutes after the onset of coronary occlusion (sCR1), 10 received HB-CPB only (HB-C

225 about symptoms that they might have during a coronary occlusion, steps that they should take, the imp

226 other cytokine combinations, at the time of coronary occlusion suppressed acute myocardial cell deat

227 three days and four to eight weeks following coronary occlusion; terminal values averaged 24 +/- 3% o

228 Four days after permanent coronary occlusion, the rates of myofibroblast (smooth m

229 On the polar maps recorded during coronary occlusion, the size of perfusion defects was me

230 After 10 minutes of acute coronary occlusion, there was an upward shift of the FRP

231 MCE can be used immediately after coronary occlusion to define ultimate IS by measuring th

232 We used a rat model of transient coronary occlusion to determine the stability of the per

233 ythmias (VAs) were subjected to percutaneous coronary occlusion to induce myocardial infarction.

234 reinstituted by increasing the number of PC coronary occlusions to 25.

235 d a spatial map of the distribution of acute coronary occlusions to test our hypothesis that plaque r

236 fluid (MIF) from dogs undergoing repetitive coronary occlusions under control conditions or during a

237 Fourteen animals underwent 40 min of coronary occlusion using a closed-chest technique.

238 e subjected to gradually developing regional coronary occlusion using an ameroid occluder placed arou

239 on was 4.1%, conversion to surgery was 0.6%, coronary occlusion was 0.8%, and new pacemaker insertion

240 , improvement in carotid patency after brief coronary occlusion was corroborated in anesthetized dogs

241 size in a model of acute infarction in which coronary occlusion was followed by prolonged reperfusion

242 An acute coronary occlusion was found in 11% of patients in group

243 stance from the ostium, the risk of an acute coronary occlusion was significantly decreased by 13% in

244 SPECT defect during coronary occlusion was similar to that obtained during p

245 of scar, but infarct size at 10 weeks after coronary occlusion was still smaller (by 50%) in Cx43(+/

246 When the second sequence of coronary occlusions was performed 6 hours after the firs

247 However, the benefits of brief coronary occlusion were abrogated by the A(2)/A(1) antag

248 ion starting 30 s after release of the index coronary occlusion were added in the presence or absence

249 ST-segment shift, associated with thrombotic coronary occlusion, were 100% and 100%, respectively.

250 lateral development in dogs with progressive coronary occlusion when given during the period of natur

251 ification of these high-risk zones for acute coronary occlusions will lead to future advances in vuln

252 Coronary occlusion with and without subsequent revascula

253 dult dogs underwent left anterior descending coronary occlusion with or without reperfusion.

254 and reperfusion before a sustained period of coronary occlusion with reperfusion delays infarct devel

255 ions in regional function: dobutamine, 5-min coronary occlusion with reperfusion up to 1 h, followed

256 Early identification of coronary occlusion with ST-segment elevation could profo

257 Group 1 dogs (n=15) underwent coronary occlusion without reperfusion, whereas group 2

258 We tested the hypothesis that acute coronary occlusion would result in loss of forces that c

259 id not alter the hemodynamic response to the coronary occlusion, yet it prevented VF in 10 of 11 anim

260 nosine for both CFR and FFR; and 3) complete coronary occlusion yielded a better hyperemic response t