ライフサイエンスコーパス: cyst fluid

1 NF-alpha accumulates to high levels in ADPKD cyst fluid.

2 has been isolated and identified within the cyst fluid.

3 growth factors present in human ADPKD liver cyst fluid.

4 could be identified in the patients' ovarian cyst fluids.

5 issues as well as in premalignant pancreatic cyst fluids.

6 e of radiographic septations or preoperative cyst fluid analysis (carcinoembryonic antigen, amylase,

7 imaging includes endoscopic ultrasound with cyst fluid analysis and cytology to confirm the type of

8 lastic pancreatic cysts; however, a detailed cyst fluid analysis for protein and genetic markers may

9 radiographic studies, endoscopic evaluation, cyst fluid analysis, and novel molecular diagnostics, ma

10 or were monitored with endoscopic US-guided cyst fluid analysis, cytologic analysis, and follow-up i

11 was performed of MCP-1 in urine, serum, and cyst fluid and MCP-1 production by mural epithelial cell

12 We purified human ZAG from breast cyst fluid and serum and produced a panel of anti-ZAG mo

13 Protein profiles of cyst fluid and serum were similar.

14 eomic profiling was performed on peritumoral cyst fluid and serum.

15 The presence of IL13 in cyst fluid and the overexpression of IL4/13 receptor cha

16 egulator (CFTR) participates in secretion of cyst fluid, and the mammalian target of rapamycin (mTOR)

17 Cyst fluid AREG levels are significantly higher in cance

18 The cellular content of pancreatic cyst fluid aspirate is often suboptimal for analysis, bu

19 ry or endoscopic ultrasonography (US)-guided cyst fluid aspiration and biopsy were included.

20 ade, and gliomatosis peritonei, but not with cyst fluid aspiration/spillage, tumor enucleation, nodal

21 ility of amphiregulin (AREG) as a pancreatic cyst fluid biomarker to differentiate non-mucinous, beni

22 ted mass spectrometry analysis of just three cyst fluid biomarkers provides highly accurate identific

23 cyst walls are responsible for secreting the cyst fluid, but the mechanism through which this secreti

24 d that ATP is released in vitro and into the cyst fluid by cystic epithelial cells in concentrations

25 study to evaluate AREG levels in pancreatic cyst fluid by ELISA from 33 patients with a histological

26 ecificity, and when used in combination with cyst fluid CA 19-9 gave a sensitivity of 87% at 86% spec

27 These biomarkers performed better than cyst fluid carcinoembryonic antigen (37%/80% sensitivity

28 ably with the accuracy of standard analyses: cyst fluid carcinoembryonic antigen (61%; 95% CI, 46% to

29 Although cyst fluid carcinoembryonic antigen is a very good marke

30 Biliary cyst fluid caused a dose-dependent induction of eNOS mes

31 lysis of the tumor markers demonstrated that cyst fluid CEA (optimal cutoff of 192 ng/mL) demonstrate

32 Of tested markers, cyst fluid CEA is the most accurate test available for t

33 These results show that bile and biliary cyst fluid contain high concentrations of ET-1 that are

34 Control bile and biliary cyst fluid contained concentrations of ET-1 25- to 42-fo

35 A subset of cyst fluids contained as much as 0.5 to 10 microM ATP, d

36 The results of EUS imaging, cyst fluid cytology, and cyst fluid tumor markers (CEA,

37 osorbent assay analysis of human ADPKD liver cyst fluid detected epithelial neutrophil attractant 78,

38 be induced by TNF-alpha, which is present in cyst fluid during cyst development.

39 Cyst fluid from patients with SCA (n = 15), non main-duc

40 thermore, we found that EPO is detectable in cyst fluid from S-HB (n = 14), while absent in CSF (n =

41 In a search for modulators of cAMP synthesis cyst fluids from 18 patients with autosomal dominant or

42 "Flash-frozen" cyst fluids from ADPKD cysts, harvested from multiple do

43 DNA mutations and proteins within pancreatic cyst fluid have identified potential biomarkers to aid w

44 echanisms by which SMYD2 might be induced by cyst fluid IL-6 and TNF-alpha in ADPKD kidneys.

45 Biliary cyst fluid increases eNOS expression and activity in an

46 87 different cyst fluid proteins, including cyst fluid inflammatory markers (CFIMs), as possible sur

47 We have shown previously shown that IL13 in cyst fluid leads to aberrant activation of STAT6 via the

48 sults suggest that the genetic evaluation of cyst fluids might be able to inform the management of th

49 Cyst fluid mucin glycoproteins and cytokines may identif

50 higher than in serum or urine were found in cyst fluids obtained from nephrectomy specimens (range,

51 -deficient murine kidneys and accumulated in cyst fluid of human ADPKD kidneys.

52 proteins significantly overexpressed in the cyst fluid of patients with mucinous cysts were CEA (med

53 In contrast, no mutations were found in the cyst fluids of 18 patients with benign tumors or non-neo

54 or-specific mutations were detectable in the cyst fluids of 19 of 23 (83%) borderline tumors, 10 of 1

55 In this study differential cyst fluid protein expression was observed between SCA a

56 assay was performed to evaluate 87 different cyst fluid proteins, including cyst fluid inflammatory m

57 ycosylation variants on specific proteins in cyst fluid samples could serve as biomarkers to aid in t

58 Methods Cyst fluid samples obtained by routine endoscopic ultras

59 All five cyst fluid samples were negative.

60 Fifty-three cyst fluid samples were obtained from patients with muci

61 Among the cyst fluid samples, the median (IQR) AREG levels for non

62 oteins implicated in pancreatic neoplasia in cyst fluid samples.

63 gy of an Smac-mimetic and TNF-alpha in renal cyst fluid, that attenuates cyst development, providing

64 lts of EUS imaging, cyst fluid cytology, and cyst fluid tumor markers (CEA, CA 72-4, CA 125, CA 19-9,

65 Mean cyst fluid vascular endothelial growth factor concentrat

66 te detrimentally to the gradual expansion of cyst fluid volume that is a hallmark of ADPKD.

67 f the sodium/potassium (Na+/K+) ratio in the cyst fluid was less than 3, or type II if the Na+/K+ rat

68 End-stage ADPKD renal tissue extracts and cyst fluids were assayed for time-dependent, chymostatin