ライフサイエンスコーパス: cysteine protease

1 ic inhibitor of calpain, a calcium-dependent cysteine protease.

2 equently exposed the mice to ovalbumin and a cysteine protease.

3 inant Dpi showed inhibitory activity against cysteine protease.

4 ion as novel regulators of the secreted SpeB cysteine protease.

5 ragment was generated by a calcium-dependent cysteine protease.

6 y functioning both as a scaffold protein and cysteine protease.

7 of SERA6 by PfSUB1 converts it to an active cysteine protease.

8 es, including speB, which encodes a secreted cysteine protease.

9 perturbs the active site of this papain-like cysteine protease.

10 ed to be cleaved by cathepsin B, a lysosomal cysteine protease.

11 aragine endopeptidase (AEP), a key endosomal cysteine protease.

12 ational maturation of SpeB, an extracellular cysteine protease.

13 hese results strongly suggest that SpvD is a cysteine protease.

14 D is an inhibitor of lysosomal and secreted cysteine proteases.

15 elucidate novel inhibitors of the falcipain cysteine proteases.

16 ective for cathepsins B and Z, two lysosomal cysteine proteases.

17 yzed possible adjuvant function of exogenous cysteine proteases.

18 posure of cystatin domains for inhibition of cysteine proteases.

19 us enhancing PMC's inhibitory ability toward cysteine proteases.

20 CLD is unable to function as an inhibitor of cysteine proteases.

21 repeating units, each capable of inhibiting cysteine proteases.

22 been exploited as inhibitors for serine and cysteine proteases.

23 hat are crucial to the enzymatic activity of cysteine proteases.

24 blocks delta-secretase but not other related cysteine proteases.

25 covery for other classes of disease-relevant cysteine proteases.

26 was blocked almost completely by inhibiting cysteine proteases.

27 RAMP were rapidly cleaved by released amebic cysteine proteases.

28 cysteine, an arrangement found in productive cysteine proteases.

29 paraginase is degraded by leukemic lysosomal cysteine proteases.

30 rall protein fold reminiscent of other plant cysteine proteases.

31 is activation of calpains-calcium-dependent cysteine proteases.

32 ity of inhibition against calpain over other cysteine proteases.

33 e Y283 is highly conserved among papain-like cysteine proteases.

34 e cytosol upon inhibition of serine, but not cysteine, proteases.

35 nfection, RIP3 is cleaved by the CVB-encoded cysteine protease 3C(pro), which serves to abrogate RIP3

36 wn to contain four domains: an N-terminal, a cysteine protease, a peptidoglycan-binding and an SH3 ba

37 and alters tight junction permeability as Eh cysteine protease A5 (EhCP-A5).

38 ine protease inhibitor but not inhibitors of cysteine proteases, acid proteases, metalloproteases, or

39 In conjunction with the cysteine protease-activatable imaging reporter Prosense

40 d granularity, demonstrating that control of cysteine protease activity by CF is critical for normal

41 In vivo, EspL cysteine protease activity contributes to persistent col

42 with the mature form, demonstrating that the cysteine protease activity critically contributes to the

43 and reveals increased inflammation-regulated cysteine protease activity in atheromata and stent-induc

44 Thus, glucosyltransferase but not cysteine protease activity is critical for TcdB-mediated

45 Mutations specifically disrupting the cysteine protease activity of PEDV nsp5 abrogated NEMO c

46 Mechanistically, the cysteine protease activity of PEDV nsp5 mediates proteol

47 elatively small group of proteins, most with cysteine protease activity that target several key prote

48 Poration does not depend on cysteine protease activity, because protease inhibition

49 We showed that Der p 1, which has cysteine protease activity, cleaves the ectodomain of pe

50 erimental AAA pathogenesis and that enhanced cysteine protease activity, due to the lack of CystC, fa

51 rgely dependent on T. foetus cell-associated cysteine protease activity.

52 This cleavage relies on 3C(pro)'s cysteine protease activity.

53 ella flexneri type III effector protein with cysteine protease activity.

54 Papain, a cysteine protease allergen with inherent adjuvant activi

55 We identified the cysteine protease Amb a 11 as a new major allergen from

56 Cathepsin S is a lysosomal cysteine protease and controls HLA-DR-antigen complex pr

57 s, 7F and E3, that specifically inhibit TcdB cysteine protease and glucosyltransferase activities, re

58 time that toxin autoprocessing occurs after cysteine protease and glucosyltransferase domains transl

59 Der p1 is a cysteine protease and major allergen from the house dust

60 retion of certain toxins, including the SpeB cysteine protease and the streptolysin O (SLO) cytolysin

61 tosis-related pathway and requires endosomal cysteine proteases and an intact fusion peptide.

62 Furthermore, an imbalance between cysteine proteases and antiproteases could be seen, whic

63 ideas for inhibitor design for papain-family cysteine proteases and strategies to progress drug disco

64 s of the N-terminal glucosyltransferase, the cysteine protease, and the C-terminal repeat region can

65 in the gut with the primary proteases being cysteine proteases, and alkaline (8 to 9) in the saliva

66 ts a new clade of previously uncharacterized cysteine proteases, and the dependence of S. aureus on L

67 a member of the papain/cathepsin L family of cysteine proteases, and the major cysteine protease of t

68 Cysteine proteases are an important class of enzymes imp

69 Protein kinase (PK)Cs and calpain cysteine proteases are highly expressed in myocardium.

70 The caspase family of cysteine proteases are highly sought-after drug targets

71 Previous studies revealed that endosomal cysteine proteases are host factors for ebolavirus Zaire

72 efore, the activities of these two lysosomal cysteine proteases are important in host defense against

73 Cysteine proteases are potent triggers of allergic infla

74 The Atg4 cysteine proteases are required for processing Atg8 for

75 Caspases, a family of cysteine proteases, are widely activated in neurons and

76 zation of limited enzymatic digestion with a cysteine protease as compared to the recently published

77 s strongly suggest that the use of endosomal cysteine proteases as host factors for entry is a genera

78 nd provide important insights for the use of cysteine proteases as immunomodulatory agents.

79 ium and support further investigation of the cysteine proteases as virulence factors in vivo and as p

80 mine a nonredundant subset of the serine and cysteine proteases as well as the barnase-barstar and Ra

81 s the biogenesis of SpeB, the major secreted cysteine protease, at a post-translational level, suscep

82 om autophagosomes, both executed by the same cysteine protease ATG4.

83 ruzi encodes two copies of autophagy-related cysteine proteases, Atg4.1 and Atg4.2.

84 LC3 is a substrate of the cysteine protease ATG4B (Autophagin-1), where cleavage g

85 reasing LC3-II availability by silencing the cysteine protease ATG4B or acute trehalose exposure incr

86 Cathepsin B (CTB) is a cysteine protease believed to be an important therapeuti

87 Certain inhibitors of serine and cysteine proteases block egress, indicating a crucial ro

88 Hyperactivation of the calcium-dependent cysteine protease calpain 1 (Cal1) is implicated as a pr

89 Mutations in the non-lysosomal, cysteine protease calpain 3 (CAPN3) result in the diseas

90 species (ROS) emission and activation of the cysteine protease calpain are required for DOX-induced m

91 We show here that the cellular cysteine protease calpain cleaves the 16E1^E4 protein af

92 t functions of a ubiquitous Ca(2+)-dependent cysteine protease, calpain-2, and of the calpain substra

93 Rs are also substrates for the intracellular cysteine proteases, calpain and caspase.

94 e CAPN1 gene, encoding the calcium dependent cysteine protease calpain1 (mu-calpain), was identified.

95 Along with these, up-regulation of the cysteine protease calpains and cleavage of caspase-12 an

96 The catalytic activity of serine and cysteine proteases can be regulated after activation by

97 vation of an intracellular caspase-1/calpain cysteine protease cascade degraded filamin, thereby seve

98 The proinflammatory cysteine protease caspase-1 is autocatalytically activat

99 flammasome assembly is the activation of the cysteine protease caspase-1, which activates the pro-inf

100 of inflammasome complexes that activate the cysteine protease caspase-1.

101 grammed cell death is the aspartate-specific cysteine protease (caspase)-8.

102 Previously, we showed that the cysteine protease cathepsin B (CatB) degrades Abeta, mos

103 The cysteine protease cathepsin B (CTSB) is frequently overe

104 The Trypanosoma brucei cysteine protease cathepsin B (TbCatB), which is involve

105 lly identified the inhibitor-binding site in cysteine protease cathepsin B, a potential drug target a

106 that Xenopus 2F3 cells apically express the cysteine protease cathepsin B, as indicated by two-dimen

107 The cysteine protease cathepsin C (CatC) activates granule-a

108 (PLS) results from mutations that inactivate cysteine protease cathepsin C (CTSC), which processes a

109 nflammatory factors and proteases, including cysteine protease cathepsin K (CTSK).

110 The cysteine protease cathepsin K has been implicated in pat

111 for cardiovascular disease and the lysosomal cysteine protease cathepsin K plays a critical role in c

112 We demonstrate an unprecedented role for the cysteine protease Cathepsin L (CTSL) in the degradation

113 The cysteine protease cathepsin L (CTSL) is often thought to

114 We show that the cysteine protease cathepsin S activates MrgprC11 and evo

115 timicrobial function and did not inhibit the cysteine protease, cathepsin L.

116 quired for optimal activity of the lysosomal cysteine protease, cathepsin S.

117 calpain with high selectivity versus related cysteine protease cathepsins, other proteases, and recep

118 V. dahliae genes encoding a Ca(2+)-dependent cysteine protease (Clp-1) and an isotrichodermin C-15 hy

119 hages with the arginine- and lysine-specific cysteine protease complex (RgpA-Kgp complex), produced b

120 We found that disrupting a VAC-localized cysteine protease compromised VAC digestive function and

121 We have identified a cysteine protease, conserved among bacteria containing t

122 family while providing new insights into how cysteine proteases contribute to itch.

123 14 has classical calpain motifs, including a cysteine protease core.

124 el in which to study RIBEs, and identify the cysteine protease CPR-4, a homologue of human cathepsin

125 Cysteine proteases (CPs) accumulate to high concentratio

126 almonella (S) carrying plasmids encoding the cysteine protease cruzipain (Cz) protects against Trypan

127 tional cleavage of the precursor SlpA by the cysteine protease Cwp84.

128 recombinant enzyme with characteristics of a cysteine protease, demonstrating that SERA5 can bind pep

129 of the Venus flytrap (Dionaea muscipula) are cysteine proteases (dionain-1 to -4).

130 suis, is a cysteine protease distinct from previous characterized s

131 Two domains, X and the papain-like cysteine protease domain (PCP), of HEV ORF1 were identif

132 main for inactivating host Rho GTPases and a cysteine protease domain for the delivery of the effecto

133 The Josephin domain is a conserved cysteine protease domain found in four human deubiquitin

134 Fusion of the most stable cysteine protease domain to the adjacent effector domain

135 in, a Ca(2+)- and Zn(2+)-binding papain-like cysteine protease domain within the nonstructural replic

136 l hexakisphosphate (InsP(6)) by an intrinsic cysteine protease domain, located next to the glucosyltr

137 ve mechanisms to fine-tune the activity of a cysteine protease dubbed RD21 (RESPONSIVE TO DESICCATION

138 he activity of EspL defines a family of T3SS cysteine protease effectors found in a range of bacteria

139 A cysteine protease encoded by enteroviruses cleaves FAK t

140 The papain-like cysteine proteases encoded by the coronavirus (SARS-CoV:

141 ity ligation (ADPL), to serine hydrolase and cysteine protease enzymes enables quantification of diff

142 rly demonstrate that Amb a 11 is a bona fide cysteine protease exhibiting a strong allergenicity.

143 n unusually specific endosomal and lysosomal cysteine protease, expressed at high levels in the PTCs

144 ZmPCP belongs to the cysteine protease family but has no closely related para

145 Our findings further validate the cysteine protease family, and BLMH and cathepsin Z in pa

146 eronyssinus, that belongs to the papain-like cysteine protease family.

147 al significance for these two members of the cysteine protease family.

148 a 11, a new major allergen belonging to the cysteine protease family.

149 of pro-Amb a 11 shows an overall typical C1A cysteine protease fold with a network of molecular inter

150 ike Leishmania predominantly express Clan CA cysteine proteases for key life cycle functions.

151 spases (MCPs) are members of a new family of cysteine proteases found in plants, fungi, and protozoa

152 ivity against the major hemoglobin degrading cysteine protease FP-2.

153 This study provides the first analysis of a cysteine protease from the digestive fluid of a carnivor

154 se Clan CE, which includes distantly related cysteine proteases from eukaryotes, pathogenic bacteria,

155 lo t 1 is characteristic for the pro-form of cysteine proteases from the C1A class.

156 Cathepsin V is a human-specific cysteine protease gene.

157 n system in rice by combining Brassica napus cysteine-protease gene (BnCysP1) with anther-specific P1

158 Calpains, calcium-activated cysteine proteases, have been shown to increase inflamma

159 rity to proteins from the NlpC/P60 family of cysteine proteases, having its secondary structure eleme

160 with putative domains for methyltransferase, cysteine protease, helicase and RNA-dependent RNA polyme

161 present a middle-down approach employing the cysteine protease IdeS under reducing conditions to obta

162 l antifungal, while several others inhibit a cysteine protease implicated in cancer.

163 esiccation 21), a granulin domain-containing cysteine protease implicated in stress responses and def

164 rphyromonas gingivalis, secretes gingipains, cysteine proteases implicated as the main factors in the

165 s protein degradation by a calcium-dependent cysteine protease in response to unsaturated fatty acids

166 n underappreciated role of the SspB and ScpA cysteine proteases in modulating S. aureus biofilm archi

167 article describes a novel role for Giardia's cysteine proteases in pathogenesis and how Giardia's dis

168 Zinc inhibits cysteine proteases, including the apoptotic caspases, le

169 vealed a high structural homology with known cysteine proteases, including the mite Der p 1 allergen.

170 Here we demonstrate that cysteine protease-induced T(H)2 responses occur via 'coo

171 )/Arg(15)) had modest adverse effects on the cysteine protease inhibition but conferred potent activi

172 asome inhibition or off-target serine and/or cysteine protease inhibition remains unresolved.

173 ough proteasome inhibition and not serine or cysteine protease inhibition, likely through positive ch

174 The cysteine protease inhibitor cystatin C is internalized b

175 The cysteine protease inhibitor cystatin C is thought to be

176 In contrast, the cysteine protease inhibitor cystatin C was expressed onl

177 er cell internalization of the extracellular cysteine protease inhibitor cystatin C, 12 variants of t

178 s efficiently inhibited by both the covalent cysteine protease inhibitor E-64 and the reversible sele

179 DeltasigB mutant through the addition of the cysteine protease inhibitor E-64 or by using Staphostati

180 Importantly, the cysteine protease inhibitor E64 prevented mucous degrada

181 ile and ubiquitously-expressed member of the cysteine protease inhibitor family that is present at no

182 Collectively, these results indicate that a cysteine protease inhibitor from bacterial origin could

183 Sialostatin L is an immunosuppressive cysteine protease inhibitor present in the saliva of the

184 The serine/cysteine protease inhibitor SCCA1 (SERPINB3) is upregula

185 structural analysis between the hCLD and the cysteine protease inhibitor stefin A showed why the hCLD

186 lution as well as complexes with the general cysteine protease inhibitor trans-epoxysuccinyl-l-leucyl

187 le abnormalities similar to that seen with a cysteine protease inhibitor, E-64 (I-1).

188 t the helminth immunomodulator AvCystatin, a cysteine protease inhibitor, induces a novel regulatory

189 the cystatin B (CysB) gene, an intracellular cysteine protease inhibitor, lead to this human disease.

190 l-characterized apoplastic effector EPIC1, a cysteine protease inhibitor, was also secreted from haus

191 nd that of its complex with a small-molecule cysteine protease inhibitor.

192 Serine and cysteine protease inhibitors also reduced Alternaria-ind

193 In vitro, cysteine protease inhibitors restored granularity, demon

194 d tolerance of antiherbivory defenses (i.e., cysteine protease inhibitors) expressed in soybean folia

195 1/2), members of the Serpin family of serine/cysteine protease inhibitors, are transcriptionally upre

196 ecific member of the cystatin superfamily of cysteine protease inhibitors, forms amyloid in vitro sug

197 In this study, the roles of rice bran cysteine protease inhibitors, oryzacystatins, were consi

198 ytes and belonging to the cystatin family of cysteine protease inhibitors.

199 one-based triazoles as potential nonpeptidic cysteine protease inhibitors.

200 ream of CTSB, a gene encoding cathepsin B, a cysteine protease involved in keratinocyte homeostasis.

201 a family of intracellular, calcium-dependent cysteine proteases involved in a variety of regulatory p

202 Thus, intracellular cysteine proteases involved in cancer-promoting processe

203 Expression of SpeB, a streptococcal cysteine protease, is critical for this process, as an i

204 A secreted cysteine protease known as streptococcal pyrogenic exoto

205 is required for cleavage by the periplasmic cysteine protease LapG and release of the adhesin from t

206 The cysteine protease legumain plays important functions in

207 TecA and other bacterial homologs bear a cysteine protease-like catalytic triad, which inactivate

208 osome biogenesis requires Autophagy 4 (Atg4) cysteine protease-mediated processing of ubiquitin-like

209 equires a previously unrecognized tripartite cysteine protease motif in EspL (Cys47, His131, Asp153)

210 Consistent with these in vitro results, a cysteine protease noncleavable mutant, TcdB-L543A, delay

211 Cathepsin S (Cat-S) is a lysosomal cysteine protease of antigen-presenting cells that is se

212 previously reported that LapG, a periplasmic cysteine protease of P. fluorescens, cleaves the N termi

213 Rhodesain, a cathepsin L-like cysteine protease of T. brucei rhodesiense, is considere

214 ed the possibility that cruzipain, the major cysteine protease of T. cruzi, is responsible for trunca

215 family of cysteine proteases, and the major cysteine protease of the protozoan Trypanosoma cruzi, th

216 olase (BLMH) and cathepsin Z, which are both cysteine proteases of a papain-like structure.

217 inhibitor of the major secreted cathepsin L cysteine proteases of F. hepatica, FhCL1 and FhCL2, and

218 of transition state inhibitors of serine and cysteine proteases of medical relevance.

219 Calcium-dependent cysteine proteases of the calpain family are modulatory

220 Treatment with cysteine proteases or with human saliva resulted in the

221 scovered three nonpeptidic inhibitors of the cysteine protease papain.

222 nical acquisition and internalization of the cysteine protease papain.

223 netic beads, we demonstrate retrieval of the cysteine protease papain.

224 comparing full length Cal1 with the general cysteine protease papain.

225 ease chymotrypsin but also weakly blocks the cysteine protease papain.

226 rradiated, it releases 1, which inhibits the cysteine proteases papain and cathepsins B, K and L up t

227 A cysteine protease, papain, is a prototypic protease alle

228 Finally, studies with the cysteine protease, papain, suggest that the reduction of

229 In this study using calcium and cysteine protease pathway-specific siRNA libraries, we i

230 cloned, expressed and purified this putative cysteine protease (PCP), which presented autoproteolytic

231 Cysteine proteases play important roles in pathobiology.

232 Papain-like cysteine proteases (PLCPs) are a large class of proteoly

233 increasing body of evidence for papain-like cysteine proteases (PLCPs) being central hubs in plant i

234 E(-/-)) mice to examine directly the role of cysteine protease/protease inhibitor imbalance in AAA fo

235 al extension also encode a sequence-specific cysteine protease, Prp, which carries out this cleavage.

236 Dipeptidyl peptidase I (DPPI) is a cysteine protease required for the activation of neutrop

237 Mutant analysis suggested the role of the cysteine protease RESPONSE TO DROUGHT21A-LIKE1 in beta-o

238 Vacuolar processing enzymes are cysteine proteases responsible for maturation of vacuola

239 c peptide sequence for the inhibition of the cysteine proteases rhodesain of Trypanosoma brucei rhode

240 duced senescence in Arabidopsis, including a cysteine protease (SAG12) and three flavonoid biosynthes

241 We demonstrate further that different cysteine proteases selectively activate specific mouse a

242 to investigate the substrate specificity of cysteine proteases, serine proteases and metalloproteina

243 hase, surface M1 protein cleavage by the GAS cysteine protease SpeB eliminated Fg binding and relieve

244 Cysteine protease SpeB is secreted from Streptococcus py

245 found that elimination of production of the cysteine protease SpeB was not necessary for emergence o

246 d necrotizing fasciitis, secretes the potent cysteine protease SpeB.

247 t of the chromosomally encoded streptococcal cysteine protease (speB) in the MGAS5005 Deltasrv backgr

248 Streptococcal cysteine protease (SpeB), the major secreted protease pr

249 unds were screened against two other related cysteine proteases (SpeB and papain).

250 s that specifically target the extracellular cysteine proteases SspB and ScpA (called Staphopains).

251 Plant metacaspases (MCPs), a family of cysteine proteases structurally related to caspases, hav

252 obes that specifically target three distinct cysteine protease subfamilies: aleurain-like proteases,

253 Cysteine proteases such as caspases play important roles

254 sub-micromolar inhibition activities against cysteine proteases such as papain and calpain as well as

255 uickly in the lungs of naive mice exposed to cysteine proteases, such as bromelain and papain, as a m

256 etected members of the transglutaminase-like cysteine protease superfamily, and all possess a non-can

257 omal activity via inhibition of trypanosomal cysteine proteases, TbCatB and rhodesain, through alkyla

258 Caspase-1 is a cysteine protease that can be activated by both endogeno

259 Cathepsin L (Cat L) is a cysteine protease that can proteolytically activate CCAA

260 opeptidase (AEP) or legumain, is a lysosomal cysteine protease that cleaves both amyloid precursor pr

261 n of the gene encoding cathepsin S (Ctss), a cysteine protease that cleaves invariant chains and prod

262 n this dysfunction of cathepsin S (Cat-S), a cysteine protease that degrades elastic fibers and activ

263 ffector domain (MCFVv) is an autoproteolytic cysteine protease that induces rounding of various cell

264 ogenic exotoxin B (SpeB) is an extracellular cysteine protease that is a critical virulence factor ma

265 Cathepsin S (Ctss) is a cysteine protease that is actively secreted in areas of

266 M4 was found to interact with cathepsin C, a cysteine protease that plays an important role in bacter

267 AvrPphB is a cysteine protease that specifically targets a subfamily

268 mediated by activated cathepsin B (CatB), a cysteine protease that translocates to the cell surface

269 ic dyad that is characteristic of C11-family cysteine proteases that are conserved in multiple pathog

270 ular activity of calpains, calcium-activated cysteine proteases that are known to contribute to cell

271 Because there are dozens of cysteine proteases that are posttranslationally regulate

272 Ovarian tumour deubiquitinases are cysteine proteases that cleave polyubiquitin chains in v

273 entified cathepsins L and Z as the lysosomal cysteine proteases that digest polyQ proteins and peptid

274 Der p 1 and Der f 1 are cysteine proteases that elicit IgE responses in 80% of m

275 Calpains are calcium-regulated cysteine proteases that have been implicated in the regu

276 Caspases are aspartate-directed cysteine proteases that have numerous cellular targets.

277 p a family of Ca(2+)-dependent intracellular cysteine proteases that include ubiquitously expressed m

278 Calpains are calcium-dependent neutral cysteine proteases that modulate cellular function and h

279 Caspases are cysteine proteases that play essential roles in apoptosi

280 Caspases are cysteine proteases that regulate embryonic development,

281 The MJD family of DUBs consists of four cysteine proteases that share a catalytic "Josephin" dom

282 d the hypothesis that activation of specific cysteine proteases, the caspases, during C. trachomatis

283 theses for the exclusive binding of FhKT1 to cysteine proteases, the importance of the Leu(15) in anc

284 Using selective inhibitors of either PKG or cysteine proteases to separately inhibit the sequential

285 rt a model in which GP cleavage by endosomal cysteine proteases unmasks the binding site for NPC1, an

286 f deubiquitinases, called ubiquitin-specific cysteine proteases (USPs).

287 prolines and that actin-related proteins and cysteine proteases were highly enriched in the group.

288 Finally, T. foetus cysteine proteases were identified as enabling cytopathi

289 ns, which are calcium-dependent nonlysosomal cysteine proteases, were activated upon ATP stimulation

290 y levels of these enzymes, in particular the cysteine proteases, were increased in a rot mutant.

291 also activates calpain, a calcium-dependent cysteine protease, which has been shown to play a critic

292 s dependent on the autoactivation of a toxin cysteine protease, which is promoted by the allosteric c

293 iquitin-like conjugation system and the ATG4 cysteine proteases, which are implicated in the formatio

294 alpain-1 and calpain-2, are Ca(+2)-dependent cysteine proteases, which have been associated with nume

295 Calpains are calcium-dependent intracellular cysteine proteases, which include ubiquitously expressed

296 C-cleavage, is mediated by the activity of a cysteine protease whose activity is independent from tha

297 Legumain is a lysosomal cysteine protease whose biological function remains poor

298 Separase is a cysteine protease with a crucial role in the dissolution

299 ubstrate for cathepsin H (CtsH), a lysosomal cysteine protease with a strong aminopeptidase activity.

300 that plant MCPs are arginine/lysine-specific cysteine proteases with caspase-like processing activiti