ライフサイエンスコーパス: damage-associated molecular pattern

1 le of a cancer/testis antigen that is a also damage-associated molecular pattern.

2 s that senses PtdSer on apoptotic cells as a damage-associated molecular pattern.

3 ecule that promotes airway inflammation as a damage-associated molecular pattern.

4 flammation and is therefore referred to as a damage-associated molecular pattern.

5 acrophages stimulated with Wt or Cot/tpl2 KO damage-associated molecular patterns.

6 lammation and innate immunity, in particular damage-associated molecular patterns.

7 platforms that form upon sensing microbe- or damage-associated molecular patterns.

8 nction as sensors of endogenous or exogenous damage-associated molecular patterns.

9 f pathogen-associated molecular patterns and damage-associated molecular patterns.

10 pathogen-associated molecular patterns, and damage-associated molecular patterns.

11 rom dying cells may also engage with TLRs as damage-associated molecular patterns.

12 eath trigger inflammation through release of damage-associated molecular patterns.

13 les such as granular enzymes, cytokines, and damage-associated molecular patterns.

14 artner of distinct receptors of microbe- and damage-associated molecular patterns.

15 33 might function as an alarmin triggered by damage-associated molecular patterns.

16 ffectors, such as cytokines, chemokines, and damage-associated molecular patterns.

17 istic biomarkers of mitochondrial damage and damage-associated molecular patterns.

18 early inflammatory responses to pathogen and damage-associated molecular patterns.

19 kers as important signals of sepsis, whereas damage-associated molecular patterns, a class of inflamm

20 For example, damage-associated molecular patterns activate an inflamm

21 luding calgranulin A (S100a8), an endogenous damage-associated molecular pattern and TLR4 agonist.

22 avenger receptor of the Ig family that binds damage-associated molecular patterns and advanced glycat

23 The lipoproteins acquire features of damage-associated molecular patterns and trigger first a

24 (i.e., presence of circulating pathogen- and damage-associated molecular patterns), and their implica

25 isms by which different modes of cell death, damage-associated molecular patterns, and specific cell

26 ological signals induced by pathogen- and/or damage-associated molecular patterns are essential for a

27 unt for the chronic autoimmune response when damage-associated molecular patterns are released after

28 Cytosolic pathogen- and damage-associated molecular patterns are sensed by patte

29 The data suggest a paradigm of damage-associated molecular pattern-based signaling wher

30 ed molecular pattern-based signaling whereby damage-associated molecular pattern binding integrins co

31 ognition of microbe, pathogen-associated and damage-associated molecular patterns by cytosolic sensor

32 e release of inflammatory mediators, such as damage-associated molecular patterns, by dying cells was

33 c anticancer treatment, tumor-derived DAMPs (damage-associated molecular patterns) can be sensed by i

34 ptors and, when challenged with pathogen- or damage-associated molecular patterns, can deliver cell-a

35 in-like lectin-G (Siglec-G) by noninfectious damage-associated molecular patterns controls innate imm

36 n pneumonia and increased levels of the mito-damage-associated molecular pattern (DAMP) cardiolipin c

37 vely during cell death; it is the prototypic damage-associated molecular pattern (DAMP) molecule and

38 ld-inducible RNA-binding protein (CIRP) is a damage-associated molecular pattern (DAMP) molecule whic

39 age through the recognition of extracellular damage-associated molecular pattern (DAMP) molecules.

40 ages stimulated by injury-induced release of damage-associated molecular pattern (DAMP) molecules.

41 Downstream damage-associated molecular pattern (DAMP) pathway activ

42 Activation of damage-associated molecular pattern (DAMP) receptors and

43 trast-enhanced MRI, resulted in an immediate damage-associated molecular pattern (DAMP) response incl

44 d, Brennan et al report that a noninfectious damage-associated molecular pattern (DAMP), heparan sulf

45 Uric acid is a damage-associated molecular pattern (DAMP), released fro

46 ile "danger signals" that are constituted by damage-associated molecular patterns (DAMP).

47 sociated immunostimulatory endogenous danger/damage associated molecular patterns (DAMPs) and a reduc

48 role of the inflammasome from one of sensing damage associated molecular patterns (DAMPs) to sensing

49 rly, cellular injury can release endogenous 'damage'-associated molecular patterns (DAMPs) that activ

50 Mitochondrial DNA damage-associated molecular patterns (DAMPs) accumulate

51 n-associated molecular patterns (PAMPs), and damage-associated molecular patterns (DAMPs) activate fa

52 eds are carried out through the detection of damage-associated molecular patterns (DAMPs) and a respo

53 the cell content and subsequent exposure of damage-associated molecular patterns (DAMPs) and cytokin

54 ammasome activation in response to metabolic damage-associated molecular patterns (DAMPs) and discuss

55 ring infection, certain S100 proteins act as damage-associated molecular patterns (DAMPs) and interac

56 Damage-associated molecular patterns (DAMPs) are conside

57 Damage-associated molecular patterns (DAMPs) are critica

58 Damage-associated molecular patterns (DAMPs) are molecul

59 Damage-associated molecular patterns (DAMPs) are release

60 Although endogenous RNAs acting as damage-associated molecular patterns (DAMPs) for pattern

61 crotic cell death with subsequent release of damage-associated molecular patterns (DAMPs) is a charac

62 ng TLR4-dependent cytokine storm mediated by damage-associated molecular patterns (DAMPs) like HMGB1.

63 om dead and dying cells can be recognized as damage-associated molecular patterns (DAMPs) or pattern-

64 sociated molecular patterns (PAMPs/MAMPs) or damage-associated molecular patterns (DAMPs) recognized

65 TLR binding to damage-associated molecular patterns (DAMPs) released by

66 LR4 (Ahmad et al., 2014) and ligands such as damage-associated molecular patterns (DAMPs) released fr

67 We propose that inflammatogenic damage-associated molecular patterns (DAMPs) released in

68 ctivated in response to structurally diverse damage-associated molecular patterns (DAMPs) such as ext

69 The concept of damage-associated molecular patterns (DAMPs) was propose

70 cluding death of neural cells and release of damage-associated molecular patterns (DAMPs), and progre

71 Endogenous danger signals, or damage-associated molecular patterns (DAMPs), are genera

72 Signals of tissue necrosis, damage-associated molecular patterns (DAMPs), cause infl

73 ry molecules released by dying cells, termed damage-associated molecular patterns (DAMPs), have been

74 two, which involves recognition of PAMPs or damage-associated molecular patterns (DAMPs), such as ur

75 In SI, endogenous damage-associated molecular patterns (DAMPS), which are

76 endogenous signals referred to as danger- or damage-associated molecular patterns (DAMPs), which are

77 o-IL-1beta to a mature form is stimulated by damage-associated molecular patterns (DAMPs).

78 cognition of markers of tissue injury termed damage-associated molecular patterns (DAMPs).

79 alerted to cell death by molecules known as damage-associated molecular patterns (DAMPs).

80 , a CREB inducer and sensor for host-derived damage-associated molecular patterns (DAMPs).

81 th by necroptosis, accompanied by release of damage-associated molecular patterns (DAMPs).

82 activated by TLR ligands, IL4, TGFbeta, and damage-associated molecular patterns (DAMPS).

83 ndritic cells and macrophages in response to damage-associated molecular patterns (DAMPs).

84 vate plant innate immunity by functioning as damage-associated molecular patterns (DAMPs).

85 endogenous triggers of this process are the damage-associated molecular patterns (DAMPs).

86 gen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs).

87 e also been implicated in the recognition of damage-associated molecular patterns (DAMPs).

88 f immunostimulatory molecules referred to as damage-associated molecular patterns (DAMPs).

89 s can be considered to represent "danger (or damage)-associated molecular patterns" (DAMPs).

90 reas others bind endogenous plant compounds (damage-associated molecular patterns, DAMPs) such as pep

91 s emit immunostimulatory signals (so-called "damage-associated molecular patterns," DAMPs), as they d

92 ndogenous molecules released by dying cells (damage-associated molecular patterns; DAMPs) activate ce

93 similar signaling pathways are activated by damage-associated molecular patterns, epigenetic plastic

94 chondrial perturbations, which function as a damage-associated molecular pattern, exacerbate NLRP3 in

95 CIH-induced release of damage-associated molecular patterns from injured CNS ce

96 Intraperitoneal injection of damage-associated molecular patterns from necrotic hepat

97 Transcriptional hyper-activation of damage-associated molecular pattern genes occurs followi

98 Pathogen-associated molecular patterns and damage-associated molecular patterns have been found to

99 or blood transfusion releases the endogenous damage-associated molecular pattern, hemoglobin (Hb), in

100 ellular energy source, ATP can also act as a damage-associated molecular pattern in both animals and

101 onnections include responses to pathogen and damage-associated molecular patterns including alarmins

102 -associated molecular patterns as well as by damage-associated molecular patterns, including microRNA

103 Both pathogen- and tissue damage-associated molecular patterns induce inflammation

104 This is associated with increased damage-associated molecular patterns, innate cytokine re

105 e airway microbiome, antimicrobial proteins, damage-associated molecular patterns, innate lymphoid ce

106 t enhancing mitochondrial resilience against damage-associated molecular patterns may play a pivotal

107 haracterize the pathophysiologic response to damage-associated molecular pattern mediated organ injur

108 n HMGB1 is released from cells and acts as a damage-associated molecular pattern molecule during many

109 The damage-associated molecular pattern molecule high-mobili

110 Thus, CIRP is a damage-associated molecular pattern molecule that promot

111 lucidated the mechanism by which the nuclear-damage-associated molecular pattern molecule, high-mobil

112 aim was to investigate the role of IL-33, a damage-associated molecular pattern molecule, in adenovi

113 associated nuclear protein and extracellular damage-associated molecular pattern molecule, is a criti

114 EDA(+) isoform of fibronectin (EDA(+)Fn), a damage-associated molecular pattern molecule, which prom

115 show that reactive astrocytes can release a damage-associated molecular-pattern molecule called high

116 In contrast, damage-associated molecular pattern molecules (DAMPs) ar

117 mediates the cellular response to a range of damage-associated molecular pattern molecules (DAMPs) in

118 oids and a neutralizing antibody targeted at Damage-Associated Molecular Pattern molecules (DAMPs) su

119 e inflammatory response upon engagement with damage-associated molecular pattern molecules (DAMPs) su

120 extracellular compartment where they act as damage-associated molecular pattern molecules (or alarmi

121 ty group box-1 and S100A9, both of which are damage-associated molecular pattern molecules and are kn

122 y of RAGE is dictated by the accumulation of damage-associated molecular pattern molecules at sites o

123 either by bacterial lipopolysaccharide or by damage-associated molecular pattern molecules released f

124 ermore, it has been ascribed to the group of damage-associated molecular pattern molecules that promo

125 g, perturbations in calcium homeostasis, and damage-associated molecular pattern molecules, among oth

126 genous ligands from damaged cells, so-called damage-associated molecular pattern molecules, can activ

127 ) is a pattern recognition receptor for many damage-associated molecular pattern molecules.

128 he local inflammatory milieu by pathogen- or damage-associated molecular pattern, molecules, and acti

129 stem is primarily initiated by pathogen- and damage-associated molecular patterns on cellular surface

130 be triggered by endogenous mediators, called damage associated molecular patterns or alarmins.

131 Innate immune receptors for pathogen- and damage-associated molecular patterns (PAMPs and DAMPs) o

132 Molecules containing damage-associated molecular patterns play an important r

133 The damage-associated molecular pattern protein HMGB1 has be

134 ng evidence that S100B acts as a cytokine or damage-associated molecular pattern protein not only in

135 Neuroinflammation is sterile, as damage-associated molecular patterns rather than microbi

136 to pathogen-associated molecular pattern and damage-associated molecular pattern recognition by the i

137 eceptors for sensing microbial molecules and damage-associated molecular patterns released from host

138 se microbe-associated molecular patterns and damage-associated molecular patterns represent a conserv

139 echanism of cross-talk between pathogen- and damage-associated molecular pattern-sensing pathways, wh

140 During infection, the release of damage-associated molecular patterns, so-called "alarmin

141 EI11 expression is controlled by PME-related damage-associated molecular patterns, such as oligogalac

142 triphosphate (ATP) is released and acts as a damage-associated molecular pattern that activates innat

143 ty group B1 (HMGB1) is a recently identified damage-associated molecular pattern that is released dur

144 nment generates versikine, a novel bioactive damage-associated molecular pattern that may facilitate

145 e is detected by TLR3 and that self-RNA is a damage-associated molecular pattern that serves as an en

146 dies reveal that melanocyte stress generates damage-associated molecular patterns that activate innat

147 terile inflammation), necrotic cells release damage-associated molecular patterns that bind to Toll-l

148 , necrotic, or apoptotic hepatocytes release damage-associated molecular patterns that initiate steri

149 However, upon stimulation with damage-associated molecular patterns, the activation of

150 ular triggers such as pathogen-associated or damage-associated molecular patterns, the NLRP1 inflamma

151 rs (TLRs), sense and respond to pathogen- or damage-associated molecular patterns, their communicatio

152 mune cells or necrotic tissues and acts as a damage-associated molecular pattern to activate Toll-lik

153 cellularly released, galectin-3 can act as a damage-associated molecular pattern to facilitate early

154 ve microbe-associated molecular patterns and damage-associated molecular patterns to activate innate

155 ciated molecular patterns and cell-intrinsic damage-associated molecular patterns to contextualize th

156 ansduction not only during MTI but also upon damage-associated molecular pattern-triggered immunity,

157 erapy, intestinal commensal bacteria and the damage-associated molecular pattern uric acid contribute

158 One of these damage-associated molecular patterns, uric acid, is incr

159 The alarmins S100A8 and S100A9 are damage-associated molecular patterns, which play a pivot

160 rtant oxidation-derived Th2 immunomodulatory damage-associated molecular pattern with potentially imp