ライフサイエンスコーパス: dorsal horn neuron

1 (i.e., calbindin-immunoreactive neurons and dorsal horn neurons).

2 afferent terminals vs inhibitory synapses on dorsal horn neurons).

3 e of central sensitization (hyperactivity of dorsal horn neurons).

4 ons preferentially target certain classes of dorsal horn neuron.

5 the spinal cord and oxidative DNA damage in dorsal horn neurons.

6 rents and increased neuronal excitability in dorsal horn neurons.

7 internalization of micro-opioid receptors in dorsal horn neurons.

8 ownstream of mGlu5 activation in spinal cord dorsal horn neurons.

9 on of Kv4.2-containing potassium channels in dorsal horn neurons.

10 dly attenuated hyperresponsiveness of lumbar dorsal horn neurons.

11 drive from the primary afferent fibres onto dorsal horn neurons.

12 cated that NR1 is colocalized with mGluR5 in dorsal horn neurons.

13 in ERK phosphorylation (pERK) in superficial dorsal horn neurons.

14 CREB-mediated transcriptional regulation in dorsal horn neurons.

15 ectively together induce pERK in superficial dorsal horn neurons.

16 ent the activation of extrasynaptic MOR-1 in dorsal horn neurons.

17 ntiation of excitatory inputs to some of the dorsal horn neurons.

18 nce excitatory transmission onto spinal cord dorsal horn neurons.

19 ive fibers may terminate onto NK1-expressing dorsal horn neurons.

20 alpha8 protein was localized only in sensory dorsal horn neurons.

21 ry sensory neurons and intrinsic spinal cord dorsal horn neurons.

22 regulation of glutamate release onto spinal dorsal horn neurons.

23 ed with prodynorphin and NK-1 in superficial dorsal horn neurons.

24 the bilateral receptive fields for selective dorsal horn neurons.

25 tween kainate receptors expressed by DRG and dorsal horn neurons.

26 tion of group I mGluRs with activated ERK in dorsal horn neurons.

27 eceptor-mediated EPSCs in cultures of spinal dorsal horn neurons.

28 ls evoked by primary afferent stimulation in dorsal horn neurons.

29 no effect on excitatory transmission between dorsal horn neurons.

30 larizing shift in GABA reversal potential of dorsal horn neurons.

31 lasticity via modulation of ERK signaling in dorsal horn neurons.

32 mulation of the tibial nerve activated these dorsal horn neurons.

33 ons were now immunoreactive as well as a few dorsal horn neurons.

34 ited at the Q/R site both in motoneurons and dorsal horn neurons.

35 tly more vulnerable to AMPA and kainate than dorsal horn neurons.

36 nd to compare these properties with those of dorsal horn neurons.

37 SP-induced NK-1 receptor internalization in dorsal horn neurons.

38 effector genes, again in primary sensory and dorsal horn neurons.

39 it activity were examined for 68 superficial dorsal horn neurons.

40 messages are mediated by glutamate action on dorsal horn neurons.

41 e in determining response characteristics of dorsal horn neurons.

42 Ca(2+) release-activated Ca(2+) channels in dorsal horn neurons.

43 e, we demonstrate that SOCs are expressed in dorsal horn neurons.

44 ion of SOCs produced an excitatory action in dorsal horn neurons.

45 lutamatergic input from primary afferents to dorsal horn neurons.

46 stent hyperexcitability of these superficial dorsal horn neurons.

47 activity-dependent Fos expression in spinal dorsal horn neurons.

48 mbined with markers of primary afferents and dorsal horn neurons.

49 be coexpressed in postsynaptic densities in dorsal horn neurons.

50 ine-mediated currents (E(glycine)) in spinal dorsal horn neurons.

51 to the regulation of glutamatergic input to dorsal horn neurons.

52 types inhibits synaptic glutamate release to dorsal horn neurons.

53 hins are present in different populations of dorsal horn neurons.

54 signal-regulated kinase (ERK) in superficial dorsal horn neurons.

55 AMPAR Ca(2+) permeability at the synapses in dorsal horn neurons.

56 ergic action and transmission in superficial dorsal horn neurons.

57 t icilin modulates the mechanosensitivity of dorsal horn neurones.

58 potentiation of glycinergic input to spinal dorsal horn neurones.

59 We conclude that MOR-expressing dorsal horn neurons (1) are not essential for determinin

60 (1) partial loss of lamina II MOR-expressing dorsal horn neurons, (2) no effect on MOR-expressing dor

61 d excitatory synaptic transmission in spinal dorsal horn neurons, a mechanism by which NMU stimulates

62 In spinal cord dorsal horn neurons, A-type currents are modulated by ex

63 w a loss of a subpopulation of glutamatergic dorsal horn neurons, abnormal sensory afferent innervati

64 after peripheral nerve injury, second-order dorsal horn neurons abnormally express Na(v)1.3, which (

65 rat: the visceromotor reflex (vmr) and L6-S1 dorsal horn neuron activity (ABRUPT and SUSTAINED neuron

66 ulation of rat ACC depressed the spinal cord dorsal horn neuron activity in response to noxious stimu

67 nal Fos expression, and colonic afferent and dorsal horn neuron activity were apparent by 1 week and

68 fect is through the modulation of the spinal dorsal horn neuron activity.

69 Fifty-two of 53 dorsal horn neurons affected by CPSA stimulation were ex

70 zation, increased sensitivity in spinal cord dorsal horn neurons after injuries, plays an essential r

71 of N-methyl-d-aspartate (NMDA) receptors in dorsal horn neurons after intradermal injection of capsa

72 and phosphorylation of CaMK II in rat spinal dorsal horn neurons after noxious stimulation by intrade

73 ein translation, was activated in rat spinal dorsal horn neurons after repeated intrathecal morphine

74 stribution in primary afferent terminals and dorsal horn neurons allows for multiple, circuit-specifi

75 at ATP induces ROS production in spinal cord dorsal horn neurons, an effect eliminated by ROS scaveng

76 chanical and thermal hypersensitivity of rat dorsal horn neurones and enhanced perceptual responses o

77 measured as augmented evoked activity of rat dorsal horn neurones and increased perceptual responses

78 hecal injection of GDNF activated rat lumbar dorsal horn neurones and inhibited intrathecal SP-induce

79 ury (SCI) can result in hyperexcitability of dorsal horn neurons and central neuropathic pain.

80 ously shown to be expressed in glutamatergic dorsal horn neurons and critical for dorsal horn develop

81 We investigated the role of spinal dorsal horn neurons and descending circuitry in plastici

82 , ERK-mediated modulation of excitability in dorsal horn neurons and ERK-dependent forms of pain hype

83 2 mediates the majority of A-type current in dorsal horn neurons and is a critical site for modulatio

84 lular signal-regulated kinase) activation in dorsal horn neurons and its contribution to central sens

85 reveal that a novel SOC signal is present in dorsal horn neurons and may play an important role in pa

86 lted in a decrease in hyperresponsiveness of dorsal horn neurons and partial restoration of behaviora

87 Recordings of synaptic currents in dorsal horn neurons and population synaptic potentials i

88 rotein (CREB) phosphorylation in superficial dorsal horn neurons and produced heat hyperalgesia after

89 consequence of superoxide build-up in spinal dorsal horn neurons and SOD-2 is a major determinant.

90 differentiation and migration of superficial dorsal horn neurons and subsequent ingrowth of cutaneous

91 at the B2 kinin receptor is expressed in rat dorsal horn neurons and that bradykinin, a B2-specific a

92 orn development, is expressed in nociceptive dorsal horn neurons and that its deletion results in the

93 rtate (NMDA)-induced activity in spinal cord dorsal horn neurons and that this enhancement is importa

94 ly sufficient for noxious heat activation of dorsal horn neurons and that, despite their polymodal pr

95 8 act upstream from Erk activation in spinal dorsal horn neurons and the calcium-AC1/AC8-dependent Er

96 o determine the changes in synaptic input to dorsal horn neurons and the GABAB)receptor function in s

97 a(+) channel within second-order spinal cord dorsal horn neurons and third-order thalamic neurons alo

98 es between the KA receptors expressed by rat dorsal horn neurons and those expressed by the primary a

99 ) contributes to the responsiveness of these dorsal horn neurons and to pain-related behaviors.

100 g in the primary sensory neurons, the spinal dorsal horn neurons, and astrocytes.

101 reduced hyperexcitability of multireceptive dorsal horn neurons, and attenuated mechanical allodynia

102 protein, reduced the hyperresponsiveness of dorsal horn neurons, and attenuated pain-related behavio

103 zed by bilateral hyperexcitability of lumbar dorsal horn neurons, and behavioral signs of central pai

104 us stimuli activate overlapping ensembles of dorsal horn neurons, and that stimulus type and intensit

105 hreshold neurons, but not wide dynamic-range dorsal horn neurons, and why it may not be effective in

106 m-chloride cotransporter KCC2 in spinal cord dorsal horn neurons are a major contributor to the centr

107 The P2X receptors on acutely dissociated dorsal horn neurons are nondesensitizing, insensitive to

108 strongly suggest that NR1 subunits in spinal dorsal horn neurons are phosphorylated following CAP inj

109 nd physiological properties of glutamatergic dorsal horn neurons are poorly characterized despite the

110 erentiation and migration of the superficial dorsal horn neurons are regulated by the LIM homeobox ge

111 n of Nav1.3 protein and hyperexcitability in dorsal horn neurons as well as pain-related behaviors re

112 that cholinergic boutons are presynaptic to dorsal horn neurons as well as to the terminals of senso

113 eripheral terminals of the nociceptor and in dorsal horn neurons, as well as later transcription-depe

114 Classification of dorsal horn neurons based on cell activity responses to

115 cient to evoke action potentials in neonatal dorsal horn neurons but was accompanied by a block of EP

116 mouse has abundant expression in superficial dorsal horn neurons, but not in the DRG.

117 the SSC will inhibit the activity of spinal dorsal horn neurons by activating the descending inhibit

118 n results in the specific loss of excitatory dorsal horn neurons by apoptosis, without any effect on

119 Preventing nerve injury-induced apoptosis of dorsal horn neurons by blocking caspase activity maintai

120 Activity induced in dorsal horn neurons by ionophoresing various mGluR subgr

121 can trigger activation of silent synapses in dorsal horn neurons by recruiting AMPA receptors.

122 ion of hyperexcitability of nociceptive deep dorsal horn neurons by TNF-alpha largely depends on the

123 Extracellular recording has shown that dorsal horn neurons can have an inhibitory surround outs

124 pain behavior reflecting hypersensitivity of dorsal horn neurons (central sensitization).

125 ts in a change in the excitability of spinal dorsal horn neurons, central sensitization, and the beha

126 ion of synaptically coupled DRG cells in DRG-dorsal horn neuron cocultures.

127 g from single wide dynamic range-type spinal dorsal horn neurons confirmed the descending nociceptive

128 Importantly, wide dynamic-range dorsal horn neurons continued to faithfully encode A-noc

129 spared nerve injury, the cumulative loss of dorsal horn neurons, determined by stereological analysi

130 fect of footshock on responses of 283 spinal dorsal horn neurons (DHNs) to urinary bladder distension

131 on induces synaptic GluR2 internalization in dorsal horn neurons during the maintenance of CFA-evoked

132 erlapping synaptic mechanisms in superficial dorsal horn neurons either by increasing excitatory syna

133 of evoked NMDAR-EPSCs and NMDAR currents of dorsal horn neurons elicited by puff NMDA application.

134 density in motoneurons to the level found in dorsal horn neurons eliminated selective motoneuron vuln

135 To characterize the subtypes of dorsal horn neurons engaged by dopamine signaling in the

136 s increases in spinal cord tissue and spinal dorsal horn neurons, especially in STT cells, after inje

137 study was made of the inhibitory effects on dorsal horn neurones evoked by chemical stimulation at i

138 excitatory postsynaptic currents (EPSCs) of dorsal horn neurons evoked by dorsal root stimulation in

139 excitatory postsynaptic currents (EPSCs) of dorsal horn neurons evoked by dorsal root stimulation.

140 ponses of superficial and deep lumbar spinal dorsal horn neurons evoked by mechanical and heat stimul

141 In addition, kainate suppressed EPSCs in dorsal horn neurons evoked by stimulation of synapticall

142 c excitatory postsynaptic currents of spinal dorsal horn neurons evoked from the dorsal root.

143 50 and 100 microg) on the responses of deep dorsal horn neurones, evoked by peripheral electrical st

144 receptors (GlyRs) play a role in control of dorsal horn neuron excitability, their relative contribu

145 at least two different populations of spinal dorsal horn neurons exist which encode for a stimulus of

146 e flexion reflex EMG activity and individual dorsal horn neuron firing properties, from excitation to

147 ordings were made from individual convergent dorsal horn neurones following electrical and natural (m

148 hanges in response properties of nociceptive dorsal horn neurons following implantation of fibrosarco

149 cluded that the inhibition of multireceptive dorsal horn neurones from GiA is dynamically activated b

150 ssed, prevents a significant portion of deep dorsal horn neurons from becoming sensitized to C-fiber

151 iation of glycine-activated current in mouse dorsal horn neurons from spinal cord slices.

152 Here we show that in spinal dorsal horn neurons >80% of mGluR5 is intracellular, of

153 in embryonic dorsal root ganglion (DRG) and dorsal horn neurons, has a role in the development of se

154 elta- and C-fibre evoked responses of spinal dorsal horn neurones in a dose related manner.

155 reshold) and 37 Class 2 (wide dynamic range) dorsal horn neurones in laminae II-VI of the lower lumba

156 Whole-cell recordings of dorsal horn neurones in postnatal rat slices revealed th

157 mediated post-discharge responses of spinal dorsal horn neurones in spinal nerve ligated rats is rep

158 on, we performed intracellular recordings of dorsal horn neurones in spinal slices from adult mice.

159 upon the electrophysiological properties of dorsal horn neurones in the adult spinal cord via intera

160 SP) were tested on a sample (n = 50) of deep dorsal horn neurones in the isolated and hemisected youn

161 es on the electrophysiological properties of dorsal horn neurones in the rat adult spinal cord.

162 nflammatory concentrations, activated spinal dorsal horn neurons in a dose-dependent manner, as measu

163 vestigate if these mediators activate spinal dorsal horn neurons in a manner consistent with itch.

164 erent (CPSA) fibers were determined on C1-C3 dorsal horn neurons in anaesthetized rats.

165 In rats, dorsal horn neurons in C1-C2 segments receive phrenic in

166 s thought to have a role in sensitization of dorsal horn neurons in certain pain states, and a recent

167 s been shown to be synaptically localized on dorsal horn neurons in culture and expressed by dorsal h

168 eceptors in the control of synaptic input to dorsal horn neurons in diabetes remains poorly understoo

169 preparations and patch-clamp recordings from dorsal horn neurons in lamina V of the rat spinal cord,

170 dynamic range (WDR) and high threshold (HT) dorsal horn neurons in mice with tumor-evoked hyperalges

171 predominantly attenuates GABAergic inputs to dorsal horn neurons in mice, an action that is opposite

172 tivation of non-NMDA receptors in the spinal dorsal horn neurons in neuropathic pain conditions.

173 ary sensory neurons and nociceptive input to dorsal horn neurons in neuropathic pain.

174 nal cord mu-opioid receptor (MOR)-expressing dorsal horn neurons in nociception and morphine analgesi

175 tsynaptic currents (EPSCs) were performed on dorsal horn neurons in rat spinal cord slices.

176 significantly potentiate glycine currents in dorsal horn neurons in rat spinal cord slices.

177 thresholds of lamina IV-V wide dynamic-range dorsal horn neurons in response to both A- and C-nocicep

178 show that mGluR1 and mGluR5 are activated in dorsal horn neurons in response to peripheral inflammati

179 protein kinases are activated in spinal cord dorsal horn neurons in response to stimulation of nocice

180 sal horn neurons in culture and expressed by dorsal horn neurons in situ.

181 synaptic excitatory postsynaptic currents of dorsal horn neurons in SNL rats.

182 patch-clamp recordings from rat superficial dorsal horn neurons in spinal cord slices at postnatal d

183 Finally, in recordings from dorsal horn neurons in spinal slices, kainate and ATPA w

184 of physiologically characterized superficial dorsal horn neurons in the barbiturate-anesthetized cat

185 lamp recordings were performed on visualized dorsal horn neurons in the lamina II in the spinal cord

186 rd, therefore, produce inhibitory effects on dorsal horn neurons in the lumbar spinal cord that recei

187 compare activity of the same single, spinal dorsal horn neurons in the physiologically intact, awake

188 pain transmission by measuring activation of dorsal horn neurons in the spinal cord in response to no

189 m between some primary sensory afferents and dorsal horn neurons in the spinal cord.

190 ronal-restricted precursor cells that become dorsal horn neurons in the superficial laminae.

191 WDR, but not HT, nociceptive dorsal horn neurons in tumor-bearing mice exhibited sens

192 amplitude of miniature EPSCs in superficial dorsal horn neurons in vitro.

193 study examines the functional connections of dorsal horn neurons in young and adult rats that have un

194 een shown that systemic morphine can inhibit dorsal horn neurons independent of the descending system

195 The differing effects of ice and icilin on dorsal horn neurones indicate different mechanisms of ac

196 -regulated kinase in superficial spinal cord dorsal horn neurons, indicative of central sensitization

197 hat neurotransmitter release from inhibitory dorsal horn neurons is affected by activation of presyna

198 known as to whether synaptic input to spinal dorsal horn neurons is altered in diabetic neuropathy.

199 d that responsiveness of multireceptive (MR) dorsal horn neurons is dramatically increased at 28 days

200 n processed in individual wide dynamic-range dorsal horn neurons is modulated by prostanergic descend

201 We examined three different populations of dorsal horn neurons; lamina I NK1R+ neurons, including p

202 P) recordings were obtained from spinal cord dorsal horn neurons (laminae I-IV) in a rat transverse s

203 brane depolarization in the majority of deep dorsal horn neurons (laminas III-VI; 83 of 139 cells), b

204 abeled only about 5% of the normal number of dorsal horn neurons, mainly in lamina IV, below the leve

205 urokinin 1 (NK1) receptor expressing (NK1R+) dorsal horn neurons, many of which are projection neuron

206 okinin 1 (NK1) receptor expressing (NK1R(+)) dorsal horn neurons, many of which are projection neuron

207 s, whereas widespread PV immunoreactivity in dorsal horn neurons marks the attainment of a mature pat

208 s between primary afferent fibres and spinal dorsal horn neurons may be inefficient or silent.

209 lutamatergic input from primary afferents to dorsal horn neurons may contribute to synaptic plasticit

210 s of normal function in parvalbumin positive dorsal horn neurons may result in the development of tac

211 fibers and the spinal cord, activate Erk in dorsal horn neurons of both adult rat and mouse spinal c

212 Spinal L6-S2 dorsal horn neurons of cervical spinal cord-transected,

213 PSCs and the frequency of miniature EPSCs in dorsal horn neurons of FK506-treated rats.

214 Whole-cell patch clamp recordings from dorsal horn neurons of neonatal rat spinal cord slices w

215 ular recordings from mechanonociceptive deep dorsal horn neurons of normal rats in vivo, we found tha

216 rents (EPSCs) were recorded from superficial dorsal horn neurons of spinal slices taken from young ad

217 we made extracellular recordings from lumbar dorsal horn neurons of the mouse in response to graded t

218 e) MAP (mitogen-activated protein) kinase in dorsal horn neurons of the spinal cord by peripheral nox

219 Hyperactivity of spinal dorsal horn neurons plays an important role in the devel

220 radykinin, by activating multiple kinases in dorsal horn neurons, potentiates glutamatergic synaptic

221 d, as nothing is known about how superficial dorsal horn neurons process sensory input from muscle ve

222 c afferents actively modulates thoracolumbar dorsal horn neuron processing of the same colonic stimul

223 er suggest that some lumbosacral superficial dorsal horn neurons project to the upper cervical dorsal

224 Many of these second-order dorsal horn neurons project to third-order neurons in th

225 of the serotonin receptor 2A (5-HT(2A)R) in dorsal horn neurons promotes spinal hyperexcitation and

226 Following neonatal carrageenan inflammation, dorsal horn neuron properties and receptive field sizes

227 s co-released with GABA from some inhibitory dorsal horn neurons raising the possibility that ATP cou

228 region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input f

229 ptive area for monosynaptic projections from dorsal horn neurons receiving sensory afferent inputs.

230 Enlarged dorsal horn neuron receptive field sizes provide a physi

231 rons and excitatory synaptic transmission in dorsal horn neurons, reduced meningeal blood flow, reduc

232 These findings demonstrate that some dorsal horn neurons release opioids when they fire at hi

233 lecular identity and function in spinal cord dorsal horn neurons remain elusive.

234 Since many PPD-expressing dorsal horn neurons respond to noxious stimulation, this

235 ere sensitive to both kainate and ATPA, most dorsal horn neurons responded only to kainate.

236 nd, and at times, opposite effects on spinal dorsal horn neuron responses to non-noxious and noxious

237 -type currents and increases excitability of dorsal horn neurons, resulting in enhanced sensitivity t

238 Dorsal horn neurons showed PRV-IR by 4.5 days.

239 Dorsal horn neurons showing excitatory responses to colo

240 ranscriptional changes in superficial spinal dorsal horn neurons (SSDHN) are essential in the develop

241 - to threefold higher in motoneurons than in dorsal horn neurons, suggesting a higher density of func

242 to enhance the frequency of EPSCs in spinal dorsal horn neurons, suggesting an increased excitatory

243 in vivo potentiates glycinergic synapses on dorsal horn neurons, suggesting that GlyR LTP is trigger

244 lutamatergic synaptic transmission in 59% of dorsal horn neurons tested, and this effect was blocked

245 ive abundance of GluR2 varied more widely in dorsal horn neurons than in motoneurons, but the mean va

246 properties of NMDA receptor channels in rat dorsal horn neurones that receive sensory inputs from an

247 l coding and central sensitization of deeper dorsal horn neurons that are important for both pain sen

248 iniature excitatory postsynaptic currents in dorsal horn neurons that could be blocked by gabapentin.

249 on cause a caspase-dependent degeneration of dorsal horn neurons that is slow in onset and persists f

250 e activity of second-order trigeminovascular dorsal horn neurons that receive peripheral input from t

251 her ablation procedure reduced the number of dorsal horn neurons that responded to noxious cold.

252 to an increase in the excitability of spinal dorsal horn neurons that results from, and far outlasts

253 We report that CCL21 is upregulated in dorsal horn neurons, that tissue levels are increased in

254 atS from microglia, which liberates FKN from dorsal horn neurons, thereby contributing to the amplifi

255 reduces the glutamatergic synaptic input to dorsal horn neurons through GABA(B) receptors.

256 NO enhances inhibitory glycinergic input to dorsal horn neurons through sGC-cGMP-protein kinase G.

257 shown to be restricted to a small subset of dorsal horn neurons, thus identifying a potential bioche

258 long-term activation of spinal cord glia and dorsal horn neurons, thus resulting in central sensitiza

259 nist, ketanserin, on the evoked responses of dorsal horn neurones to electrical, mechanical and therm

260 e sites were tested against the responses of dorsal horn neurones to noxious and innocuous stimuli ap

261 study, the responses of single lamina III-V dorsal horn neurons to an innocuous A beta fibre brush s

262 ted the excitatory response of thoracolumbar dorsal horn neurons to colorectal distention (CRD) and d

263 this study, the response of the spinal cord dorsal horn neurons to graded heat stimuli were characte

264 t inhibition of the responses of spinal cord dorsal horn neurons to higher intensity mechanical stimu

265 t inhibition of the responses of spinal cord dorsal horn neurons to higher intensity mechanical stimu

266 s, responses of primary afferents and spinal dorsal horn neurons to mechanical and thermal stimuli we

267 The response of the spinal cord dorsal horn neurons to mechanical stimuli are classified

268 In tests of responses of spinal dorsal horn neurons to mechanical stimuli, the group mea

269 subsets of primary afferents and superficial dorsal horn neurons to reduce both primary afferent sens

270 The prolonged responses of superficial dorsal horn neurons to SLIGRL-NH(2) and 5-HT suggest a r

271 o determine the responses of the spinal cord dorsal horn neurons to stimulation of the primary somato

272 ibution of plasticity in primary sensory and dorsal horn neurons to the pathogenesis of pain, identif

273 In tests of responses of spinal dorsal horn neurons to thermal stimuli, intraplantar adm

274 excitatory and inhibitory synaptic inputs to dorsal horn neurons using whole-cell recordings in rat s

275 ory synaptic inputs to mouse lamina I spinal dorsal horn neurons, using laser scanning photostimulati

276 acid (NMDA) receptor hyperactivity in spinal dorsal horn neurons via inhibition of the extracellular

277 urrents elicited by puff NMDA application to dorsal horn neurons was also significantly greater in FK

278 odulation of inhibitory transmission between dorsal horn neurons was preserved in cells from either G

279 y of spontaneous and miniature EPSCs in most dorsal horn neurons was profoundly increased in FK506-tr

280 In contrast, nNOS staining in dorsal horn neurons was unaltered by these manipulations

281 and patch-clamp recordings from spinal cord dorsal horn neurons, we examined excitatory and inhibito

282 m-sap) to selectively destroy MOR-expressing dorsal horn neurons, we sought to determine the role of

283 KN immunoreactivity and mRNA are confined to dorsal horn neurons, we suggest that under neuropathic c

284 underlying this sensitization of superficial dorsal horn neurons, we undertook a genome-wide microarr

285 s of electrically evoked responses of spinal dorsal horn neurones were made in halothane anaesthetise

286 d CREB in both ipsilateral and contralateral dorsal horn neurons were dramatically reduced in antisen

287 Dorsal horn neurons were found to be synaptically driven

288 Spinal motoneurons and dorsal horn neurons were isolated from embryonic rats an

289 Thirty-four wide dynamic range spinal dorsal horn neurons were recorded in response to graded

290 Dorsal horn neurons were recorded in the rat thoracolumb

291 Thirty-two wide dynamic range spinal dorsal horn neurons were recorded, in response to graded

292 es 1 (AC1) and 8 (AC8), activation of Erk in dorsal horn neurons were significantly reduced or blocke

293 n in KA receptor-mediated current density in dorsal horn neurons, whereas GluR5 deletion caused no ch

294 le internalization of SP receptors (SPRs) in dorsal horn neurons, which may provide a pharmacological

295 n of prodynorphin and neurokinin-1 (NK-1) in dorsal horn neurons, which was suppressed by intrathecal

296 le-unit recordings were made from L4-L5 deep dorsal horn neurons (wide dynamic range and nociceptive

297 B(2) receptors are coexpressed in dorsal horn neurons with protein kinase A (PKA) and the

298 Dorsal horn neurons with stronger C-nociceptor input wer

299 e cluster were depressed in both ventral and dorsal horn neurons within 24 h after injury, followed b

300 that altering the activity of MOR-expressing dorsal horn neurons would be antinociceptive and of inte