ライフサイエンスコーパス: endonuclease V

1 operty that distinguishes it from Thermotoga endonuclease V.

2 r reveals a novel 3'-exonuclease activity in endonuclease V.

3 g reveals a novel 3'-exonuclease activity in endonuclease V.

4 , or xanthine in a similar manner to E. coli endonuclease V.

5 a homologue of the bacteriophage T4-encoded endonuclease V.

6 lobutane pyrimidine dimer-specific enzyme T4 endonuclease V.

7 cis-syn dimer-specific cleavage with T4 denV endonuclease V.

8 DNA required for specific recognition by T4 endonuclease V.

9 onucleosomes and substantial reduction of T4 endonuclease V accessibility to cyclobutane pyrimidine d

10 Binding analysis indicates that Salmonella endonuclease V achieves tight binding to deoxyuridine-co

11 human alkyltransferase, suggesting that the endonuclease V activity may also repair a promutagenic l

12 her the deficiency nor the overproduction of endonuclease V affected the growth of the single-strande

13 ll-known inosine-dependent endonuclease, Tma endonuclease V also exhibits inosine-dependent 3'-exonuc

14 ysis using 3'-labeled DNA indicates that Tma endonuclease V also possesses non-specific 5'-exonucleas

15 Endonuclease V, an enzyme known for its enzymatic activi

16 omology between the PIWI domain of Ago-2 and endonuclease V and identified potential active-site amin

17 ically inhibits cleavage at the cs CTD by T4 endonuclease V and photoreversal by UV photolyase.

18 found in many DNA repair enzymes such as T4 endonuclease V and uracil DNA glycosylase.

19 indicates that the active site of Salmonella endonuclease V can accommodate pyrimidine-containing mis

20 , E89, D110, and H214 in Thermotoga maritima endonuclease V catalysis.

21 generated by deoxyuridine incorporation and endonuclease V cleavage.

22 The bacterial DNA repair enzyme, T4 endonuclease V, delivered intracellularly, increases the

23 cally compromised mutants (E23Q and E23D) of endonuclease V demonstrate altered affinities for the py

24 Endonuclease V (deoxyinosine 3' endonuclease), the produ

25 ylguanine-DNA alkyltransferase (AGT) with an endonuclease V domain.

26 Endonuclease V, encoded by the nfi gene, initiates remov

27 Endonuclease V (endo V) recognizes a broad range of aber

28 Endonuclease V (endo V) recognizes and cleaves deoxyinos

29 T4 Endonuclease V (EndoV) is a base excision repair enzyme

30 Endonuclease V (EndoV) is a ubiquitous protein present i

31 Endonuclease V (EndoV) is an enzyme with specificity for

32 ation scanning method that sequentially used endonuclease V (EndoV) to nick at mismatches and DNA lig

33 Salmonella endonuclease V exhibits limited turnover on cleavage of

34 Within the endonuclease V family, the substrate specificities are d

35 ndonuclease to 3'-exonuclease mode switch by endonuclease V for removal of deaminated base lesions du

36 Under optimal cleavage conditions, endonuclease V forms two stable complexes with DNA conta

37 Endonuclease V from bacteriophage T4, is a cis-syn pyrim

38 Endonuclease V from Escherichia coli has a wide substrat

39 totypical enzyme studied for this pathway is endonuclease V from the bacteriophage T4 (T4 bacteriopha

40 A thermostable endonuclease V from the hyperthermophilic bacterium Ther

41 ed deamination lesion cleavage activities of endonuclease V from the macrophage-residing pathogen, Sa

42 Unlike endonuclease V from Thermotoga maritima, Salmonella endo

43 the endonuclease and exonuclease activity in endonuclease V from Thermotoga maritima.

44 Disruption of the endonuclease V gene, nfi, rescues the HAP sensitivity di

45 A lethality is suppressed by inactivation of endonuclease V (gpnfi) specific for DNA-hypoxanthines/xa

46 oxyuridine-specific endonuclease activity of endonuclease V has a divalent metal requirement similar

47 These results suggest that endonuclease V has a significant role in the repair of d

48 Endonuclease V has been combined with a high-fidelity DN

49 replication, the T[c,s]T was detected by T4 endonuclease V in about one-half (46 +/- 9%) of the clos

50 T4 endonuclease V-incised DNA was processed in the same way

51 Our results suggest that endonuclease V incision of DNA containing HAP leads to i

52 rations greater than those determined for T4 endonuclease V, indicating a possibly stronger electrost

53 by the pyrimidine dimer-specific enzyme, T4 endonuclease V, indicating that complete replication of

54 Endonuclease V initiates repair of deaminated base damag

55 The enzyme endonuclease V initiates repair of deaminated DNA bases

56 Endonuclease V is a deoxyinosine 3'-endonuclease which i

57 T4 endonuclease V is a glycosylase/apurinic (AP) lyase that

58 Endonuclease V is a pyrimidine dimer-specific DNA glycos

59 Endonuclease V is an enzyme that initiates a conserved D

60 Endonuclease V is an enzyme that initiates a conserved D

61 recognition and strand nicking mechanism of endonuclease V is presented.

62 Endonuclease V is specific for single-stranded DNA or fo

63 th other enzymes known to use base flipping, endonuclease V is unique in that it moves the base oppos

64 guing possibility that there may be other T4 endonuclease V-like enzymes with specificity toward othe

65 e notion that two metal ions are involved in endonuclease V-mediated catalysis.

66 or removal of deaminated base lesions during endonuclease V-mediated repair.

67 An nfi (endonuclease V) mutant and a recA mutant were selectivel

68 An nfi (endonuclease V) mutant was grown anaerobically with nitr

69 s generated when replication forks encounter endonuclease V-nicked DNA.

70 Endonuclease V nicks damaged DNA at the second phosphodi

71 tructure, provide a detailed architecture of endonuclease V-nontarget DNA interactions.

72 Endonuclease V obtained from Thermotoga maritima prefere

73 ining the activity of endonuclease IV and T4 endonuclease V on highly purified and UVA-irradiated pUC

74 y purified native and synthetic DNA using T4 endonuclease V, photolyase, and anti-CPD antibodies stro

75 binding site for the dimer-specific T4 denV endonuclease V repair enzyme by chemical and enzymatic f

76 air, initiated by uracil-DNA glycosylase and endonuclease V, respectively.

77 e find that only approximately 60% of the T4 endonuclease V-sensitive sites, which are commonly count

78 Wild type T4 endonuclease V shows an 8-fold decreased affinity for a

79 imers, are also revealed using the enzyme T4 endonuclease V (T4 endo V).

80 se (Fpg), endonuclease III (endo III) and T4-endonuclease V (T4-endo V) to characterize DNA lesions.

81 Liposomes containing T4 endonuclease V (T4N5) were applied to the site of UV exp

82 ogs and catalytically inactive mutants of T4 endonuclease V, this study investigates the discrete ste

83 A metal ion enhances the binding of endonuclease V to double-stranded and single-stranded ox

84 e conserved positions of Thermotoga maritima endonuclease V to identify amino acid residues involved

85 tifs of the thermostable Thermotoga maritima endonuclease V to probe for residues that affect DNA-pro

86 The binding of endonuclease V to this duplex was analyzed by gel mobili

87 ophoresis separation of UV-irradiated and T4 Endonuclease V treated plasmids.

88 ion of the supercoiled plasmid assay with T4 Endonuclease V treatment of irradiated plasmids and AFM

89 inosine- and mismatch-specific activities of endonuclease V was found to have different divalent meta

90 Recently, the first sequence homolog of T4 endonuclease V was identified from chlorella virus Param

91 eas liposomes containing heat-inactivated T4 endonuclease V were ineffective.

92 ine keratinocytes in vitro with liposomal T4 endonuclease V, which accelerates the repair of cyclobut

93 stic nature in the active site of Salmonella endonuclease V, which allows the enzyme to enfold both p

94 ystal structure of a catalytically deficient endonuclease V with pyrimidine dimer-containing DNA, fou

95 ed pyrimidine dimer-specific glycosylase, T4 endonuclease V, with its substrate DNA.