ライフサイエンスコーパス: event

1 ric oxygen on the Earth (the Great Oxidation Event).

2 ind the reasons for this unusual replacement event.

3 cated chromosome ends as a single elongation event.

4 ting the downstream sequelae of this primary event.

5 the folding occurs after the initial binding event.

6 ents had a serious treatment-related adverse event.

7 ssion in mouse NK cells is a late activation event.

8 h associated adverse cardiovascular and limb events.

9 ic retinopathy, with no unanticipated safety events.

10 iation and termination are inherently random events.

11 viding evidence of interspecies transmission events.

12 te time cutoff for reporting of reintubation events.

13 ervention was high and there were no adverse events.

14 be recovered by prevention of cardiovascular events.

15 e how rainfall in the region responds to D-O events.

16 risk of complicated appendicitis and adverse events.

17 tcomes included major adverse cardiovascular events.

18 effects on loge(CAC+1) and incident coronary events.

19 le shapes, through stereotyped morphogenetic events.

20 is not a simple continuation of gastrulation events.

21 ant to understand underlying early molecular events.

22 The main safety measure was adverse events.

23 the Common Terminology Criteria for Adverse Events.

24 practices can prevent ventilator-associated events.

25 flow, antibiotic use, or nonserious adverse events.

26 ath, sudden death, and other cardiac adverse events.

27 se events or discontinuations due to adverse events.

28 e even a feature of Phanerozoic ocean anoxic events.

29 the risk for mortality, stroke, and cardiac events.

30 ase the prevalence of cardiovascular disease events.

31 84.8% of sediment loss across all high wind events.

32 atelet therapy, and long-term cardiovascular events.

33 vity that influences several mRNA processing events.

34 ugh discrete, single-electron transfer (SET) events.

35 ore conducive for intrafacility transmission events.

36 n complex that mediates downstream signaling events.

37 respectively, in a chain of self-reinforcing events.

38 aneous and inhibits Ca(2+)-triggered release events.

39 among participants who experienced an ASCVD event (0.390; 95% CI, 0.312-0.467 vs 0.08; 95% CI -0.001

40 orted low rates of death and serious adverse events (0% to 1.25%) in nontransported patients after su

41 %), anastomotic leakage (15.9%), and cardiac events (13.5%).

42 outcomes were treatment failure and adverse events 14 days after diagnosis.

43 vors were hospitalized for a cerebrovascular event-40% higher than expected (SHR=1.4, 95% confidence

44 Ninety percent survived the event, 68% with return of spontaneous circulation and 22

45 f 3096 acute cerebral or peripheral vascular events, 748 (24.2%) were AF-related.

46 In grafts surviving at least 90 days, early events (acute rejection [AR] and delayed graft function

47 r-voxilaprevir therapy because of an adverse event (AE).

48 Safety measures included adverse events (AEs), clinical laboratory tests, vital signs, el

49 or vitreous detachment being a common ocular event affecting most individuals in an aging population,

50 c experienced an extremely anomalous warming event after an extraordinary increase in air temperature

51 reatment failure was a relatively infrequent event after I-125 brachytherapy in our series.

52 factors in primary cells or during the early events after SIV infection and suggest that the level of

53 accurate reclassification of risk for ASCVD events among these individuals.

54 primary outcome was the incidence of adverse events among vaccine and placebo recipients throughout t

55 Receptor signaling relays on intracellular events amplified by secondary and tertiary messenger mol

56 The Kaplan-Meier time-to-event analyses showed that OCT detected progression earl

57 A time-to-event analysis was performed to examine the occurrence o

58 ,7-cyclooctatetraenyl via a single-collision event and opens up a versatile, unconventional path to a

59 erstanding and prediction of El Nino/La Nina events and also may be applied in the investigation of o

60 in early childhood exposure to unpredictable events and environments.

61 pulation dynamics after multiple disturbance events and for management of river flows and fire regime

62 deficiency syndrome (AIDS)-related (NLR-NAR) events and mortality in a cohort of human immunodeficien

63 c imaging, is associated with cardiovascular events and predisposes to the development of clinically

64 region scanned, type, dose, related adverse events and route of administration of sedatives as well

65 gic asthma that acts upstream of proallergic events and suggest that targeting this molecule could be

66 The homogeneity of these severe weather events and their association with the ocean temperatures

67 Aging is a biologically universal event, and yet the key events that drive aging are still

68 s or TIAs, 42 myocardial infarctions, 156 HF events, and 38 cardiovascular deaths occurred.

69 s unclear why such independent amplification events, and associated receptor overexpression, would be

70 ve of others, when imagining future and past events, and during mind wandering.

71 rature of seawater with more extreme thermal events, and frequent rainfalls in some coastal regions.

72 tereotypical sequential pattern during ictal events, and that these stereotypical patterns were repro

73 Treatment-related adverse events (any grade) prompted treatment discontinuation in

74 Two of the three events are contemporaneous with large-magnitude paleoear

75 Colonization events are crucibles for rapid evolution, but it is not

76 xact timing of and relationships among these events are debated because of poor age constraints and c

77 Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impa

78 Prevention strategies for medication-related events are reviewed by medication use process node (pres

79 Time-lapse imaging reveals that branching events are synchronized across distant locations within

80 Even if events are under recorded, this measure could provide an

81 ATATE uptake in patients with recent carotid events, assessed inter- and intraobserver variability of

82 ents died from non-treatment-related adverse events associated with death, and one patient died from

83 ines of the binding pocket of HCAII, binding events associated with enthalpically favorable rearrange

84 h FLNC reads, including a large number of AS events associated with rhizome systems.

85 However, the adverse events associated with smoking limit its clinical signif

86 ferences in risk of systemic serious adverse events between these two anti-VEGF drugs; i.e., relative

87 uce the risk of major adverse cardiovascular events, but did reduce the incidence of diabetes.

88 do not necessarily represent inter-dependent events, but MafB is broadly involved in both the process

89 26 (39%) of 44 patients had grade 3 adverse events, but no grade 4 events were reported.

90 of patients with at least 1 skeletal-related event by disease type, pain as assessed by the Brief Pai

91 % (P=0.033) and major adverse cardiovascular events by 25% (P=0.037) during the initial trial phase a

92 TRIX-Access (Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implement

93 scores the potential predictability of these events by two-to-three weeks, which offers hope in mitig

94 Our findings indicate that congruent events can trigger an accelerated onset of neural encodi

95 ry objectives included evaluation of adverse events, changes in sexual quality of life using the Canc

96 e larger fluctuations in archaeal cell cycle events contribute to cell size variability and control.

97 a product of both alpha- and gamma-cleavage events, could also induce TrkB phosphorylation.

98 een shown to be predictive of cardiovascular events (CVEs) in patients who are at high cardiovascular

99 nts experienced intrahospital cardiovascular events (CVEs) including 281 (23.8%) with heart failure,

100 disease were followed until their first CHF event, death, last follow-up date, or December 31, 2011.

101 The overall rate of serious adverse events did not differ between treatment groups, although

102 ed to TASC, the proportion of cardiovascular events did not markedly decrease over the last two decad

103 tified 26 ancient and more recent polyploidy events distributed throughout Caryophyllales.

104 ied into point stresses, where a temperature event during a sensitive stage drives a reduction in yie

105 is used to detect ligand binding as blocking events during DNA unzipping, allowing determination of l

106 a 50-min movie, then verbally described the events during functional MRI, producing unguided detaile

107 Adverse events (eg, lethargy, diarrhoea, rash, and nausea) impro

108 There were no adverse events either immediately or at 2-week follow-up.

109 rarchal severity to derive a total score for events encountered during the entire follow-up experienc

110 multaneously, enabling the reconstruction of events exhibiting remarkable complexity.

111 Nine patients died from adverse events; five of these deaths were judged to be related t

112 This event followed the suspected introduction of ZIKV in Bra

113 Finally, to dissect early and late events following interspecific hybridization, we examine

114 face in contact with a cavity, a fundamental event for all subsequent development.

115 ctivation of the STAT3 pathway, an essential event for uncontrolled cellular proliferation and transf

116 osis in relation to multiple differentiation events for bipolar cells (BCs) in the zebrafish retina u

117 viruses must antagonize antiviral signaling events for survival.

118 (89% +/- 3% vs 90% +/- 4%; Plog-rank = .64), event-free survival (EFS; 87% +/- 3% vs 89% +/- 4%; Plog

119 emission with incomplete recovery), inferior event-free survival as well as overall survival in both

120 BG led to lower rates of 5-year survival and event-free survival than on-pump CABG.

121 report a record of 54 detected annihilation events from a single release of the trapped anti-atoms a

122 followed-up for medically certified cardiac events from January 1994 to December 2014.

123 disease and subsequent injury after ischemic events, fundamental knowledge in these areas lag behind

124 4sU-RNA-seq to identify aberrant DNA-binding events genome wide and ectopic transcriptional consequen

125 p in atmospheric oxygen, the Great Oxidation Event (GOE), began in the early Paleoproterozoic in asso

126 es, 55-76 yr; apnea-hypopnea index, 0.2-96.6 events/h) were evaluated by magnetic resonance imaging.

127 12 patients reported serious adverse events; haemolysis and pyrexia were the most common (eac

128 Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders.

129 known and it is likely that N-Src signalling events have been misattributed to C-Src because they can

130 Our results suggest that chance events have played important and possibly opposing roles

131 sk of death, hospitalization, thromboembolic events, heart failure (HF), and AF progression.

132 96 to 8.78) for major adverse cardiovascular events, hospitalizations, and vascular access thrombosis

133 ations) a lower risk of major cardiovascular events; however, they also had lower ischemic risk.

134 mainly relies on the declaration of adverse events, identification of their predictors, self-assessm

135 y breast tumors, confirming many of the exon events identified in the TCGA cohort.

136 cells within the vascular wall is a critical event in chronic inflammatory processes, such as atheros

137 chanical ventilation is viewed as an adverse event in ICUs.

138 4 Cygni, showing a rapid synchrotron cooling event in its 2015 outburst, we present a precise 461 +/-

139 The first cellular differentiation event in mouse development leads to the formation of the

140 The most common serious adverse event in the active surveillance group was myocardial in

141 rmation to aggressive lymphoma is a critical event in the clinical course of follicular lymphoma (FL)

142 s taken during two rainfall and one snowmelt event in two watersheds with contrasting levels of urban

143 Stochastic events in a single ion channel system can be measured us

144 g-term aspirin use, the changes of molecular events in AM but not IM may be an important factor in th

145 ntly at centromeres during G1, mediate early events in centromere establishment at an ectopic chromos

146 independently associated with cardiovascular events in coronary artery disease (CAD) patients and red

147 complexes and transcription-repair coupling events in genes throughout the genome.

148 Dramatic events in human prehistory, such as the spread of agricu

149 t BRAF-inactivating mutations are initiating events in lung oncogenesis.

150 s is more efficacious than targeting private events in reducing the tumor burden.

151 We recorded adverse events in ten (34%) of 29 patients given twice-weekly re

152 the formation and storage of memories about events in the environment that predict the availability

153 macrophages, predicts future cardiovascular events in the general population.

154 ng, for the increased risk of neurocognitive events in the ongoing outcome studies and post-marketing

155 nding the mechanisms by which immune-related events in the periphery can influence brain processes is

156 d multiple sub-populations and recombination events in these diverse mixtures.

157 Acute CHD events included myocardial infarctions (MIs; nonfatal an

158 s (range, 3.2-10.1 years), 1203 incident CVD events, including 916 coronary heart disease cases, were

159 in an increased number of abortive infection events, including bursting of ITs and a reduction in the

160 nising, responding to and disclosing adverse events, including errors and near misses.

161 integration of semantic information with the event input.

162 otein levels, and the risk of cardiovascular events involving 102837 participants from 14 cohort or c

163 Local endocytic events involving receptors for axon guidance cues play a

164 tion, two further interspecies recombination events involving the S gene were identified, suggesting

165 This event is then followed by the dynamic formation of filam

166 We show that targeting truncal events is more efficacious than targeting private events

167 sk of all-cause mortality and cardiovascular events is no higher than in healthy nondonors.

168 eclining monsoon, the number of extreme rain events is on the rise over central India.

169 Whether it prevents cardiovascular events is uncertain.

170 ifficult because the initiation of endocytic events is unpredictable.

171 onnections between the apoptotic cascade and events leading to extrusion are not fully understood.

172 These events likely underpin the improvement in oocyte quality

173 verexpressed in the absence of known genetic events linked to cetuximab resistance.

174 ed the occurrence of a major adverse cardiac event (MACE) assessed as the composite of cardiac death,

175 1 and T2MI, and major adverse cardiovascular events (MACE, a composite of all-cause death, nonfatal m

176 NHE inhibitors on the risk of cardiovascular events may be enhanced when heart failure and glucose in

177 How these events may influence one another is only partly known.

178 Frequency of adverse events, mostly mild self-limited joint and back pain, di

179 patient died from treatment-related adverse events (myositis in addition to grade 3 thyroiditis, gra

180 Two (1%) of 166 patients had serious adverse events; neither were considered related to study drug tr

181 key intermediaries between peripheral immune events, neuronal processing, and potentially cognition.

182 A primary end-point event occurred in 68 of 1012 patients (6.7%) in the iFR

183 ixaban, 12886 patients), 4770 major bleeding events occurred during 447037 person-quarters with NOAC

184 In this study, extreme rainfall and snowfall events occurred during a 3-year field experiment, allowi

185 Major adverse cardiac events occurred in 1.1% and 4.2% of everolimus-treated a

186 -hospital major adverse cardiac and cerebral events occurred in 2.0% in fTRA and 2.9% in TFA (P=0.40)

187 Minor adverse events occurred in 22% of patients in the control group

188 Drug-related serious adverse events occurred in 28 (38%) of 74 patients.

189 nly grade 1 (mild) local or systemic adverse events occurred in both groups.

190 tment groups, although some specific adverse events occurred more often in the intensive group.

191 We report a "polyclonal" autoimmune event occurring in the airways of prednisone-dependent a

192 Serious adverse events occurring in more than two patients included alan

193 pared with rat claustrum are consistent with events occurring in population subsets rather than the f

194 or tracing the source of contamination in an event of a B. canis outbreak.

195 3), and this is hypothesized to be a driving event of DIPG oncogenesis.

196 enrollment and at 6 months (or prior, in the event of early treatment failure).

197 iral RNA-Gag interactions are the nucleation event of infectious virion assembly, ensuring that one R

198 h a conformational change in BTN3A1 is a key event of pAg sensing that ultimately leads to T cell act

199 The most common adverse events of grade 3 or higher during treatment were neutro

200 Adverse events of grade 3 or higher were reported in 87% of the

201 The most common adverse events of grade 3 or worse severity were anaemia (38 [19

202 quitin-proteasome systems regulate the major events of meiotic prophase in mouse.

203 In the presence of tRNA, blocking events of single-channel currents through the pore forme

204 ate the influence of a major biomass burning event on the light absorption properties of atmospheric

205 For 1 event, opposite polarity leaders were observed to accele

206 VF progression was reached if either the event or trend analysis reached significance.

207 mary outcome was a composite of long-term CV events or death, which was assessed via national health

208 There were no serious adverse events or discontinuations due to adverse events.

209 ant differences in local or systemic adverse events or laboratory abnormalities between the PfSPZ Vac

210 ce or new breast cancer, intolerable adverse events, or consent withdrawal occurred.

211 hreefold increase in widespread extreme rain events over central India during 1950-2015.

212 mportant for reducing the risk of future CHF events, particularly among HIV and hepatitis C infected

213 natomy is associated with increased ischemic events, particularly within the first year after PCI.

214 ngly, we showed that the number of infection events per cell during cell-free HIV-1 infection follows

215 mean (SD) SMR was 0.46 (1.06) vs 0.50 (1.50) events per year in the every 4 weeks vs every 12 weeks g

216 bidity rate (mean number of skeletal-related events per year), and, in a subset of 553 patients, supp

217 show that the occurrence of extreme rainfall events, primarily in the break phase of an LF-ISO cycle,

218 n recruited APC and TC may occur as an early event promoting allergic airway inflammation.

219 moted tolerance of chromosome missegregation events, propagation of aneuploidy, and genetic heterogen

220 Rate of adverse events, quality of life, and patient satisfaction were n

221 Major adverse cardiac and cardiovascular event rate at 30 days was low (4%) and occurred in 1 pat

222 5% confidence interval for the difference in event rates fell within the prespecified noninferiority

223 s excellent prognostic information, with low event rates in patients with normal myocardial perfusion

224 1007 (6.1%) in the FFR group (difference in event rates, 0.7 percentage points; 95% confidence inter

225 tients in the stent group (2-year cumulative event rates, 3.5% vs. 0.9%; hazard ratio, 3.87; 95% CI,

226 Recurrent MI, CHD events (recurrent MI or a coronary revascularization pro

227 y subjects with Parkinson's disease using an event-related functional MRI (fMRI) experiment design.

228 ion of T2MI on its incidence, treatment, and event-related mortality, thereby addressing an important

229 In the present study, event-related potential (ERP) and behavioral measures we

230 (sympathetic adrenal medullary system), EEG event-related potentials (nociceptive cortical activity)

231 Mechanisms that orchestrate these events remain poorly understood.

232 The Food and Drug Administration Adverse Event Reporting System (FAERS) remains the primary sourc

233 clathrin waves, but not individual endocytic events, requires feedback from downstream factors, inclu

234 or placebo (32 of 255 [12.5%]); all adverse events resolved without sequelae.

235 s (VSMCs) phenotypic switch, one of the main events responsible for bare metal in-stent restenosis af

236 have emerged from a recent gene duplication event resulting from the ongoing diversification of sHsp

237 Ancestral reconstruction of transmission events reveals that intraspecific PLVA transmission has

238 reate a hub around which nighttime signaling events revolve, including inactivation of KaiA and recip

239 We performed a discrete event simulation to forecast patient characteristics and

240 The smaller event sizes in bat claustrum compared with rat claustrum

241 tion using a new database of individual rain events spanning the contiguous United States.

242 <0.0001), and risk of cardiovascular disease events (standardised hazard ratio 1.59, 95% CI 1.27-1.98

243 ual outcome of the first versus second NAION events (standardized mean differences of visual acuity 0

244 tably (suppressed agonist Emax) in signaling events such as guanosine 5'-3-O-(thio)triphosphate bindi

245 Apoplastic events such as monolignol oxidation and lignin polymeriz

246 MRS2365 (5'-diphosphates) in some signaling events, such as extracellular signal-regulated kinase 1/

247 Frost is an important episodic event that damages plant tissues through the formation o

248 sure in connection with an abnormal cortical event that underlies a neurological disorder.

249 een the abundance of insight gained into the events that constitute the metastatic cascade and the pa

250 iologically universal event, and yet the key events that drive aging are still poorly understood.

251 ity-related complications, but the molecular events that initiate and propagate such inflammation rem

252 Finally, the initiating events that lead to gene body methylation are discussed

253 re initiated by loss-of-heterozygosity (LOH) events that lead to the replacement of single, functiona

254 The most common serious adverse events that occurred through week 24 were anaemia (10 [5

255 hat principal cell discharges dominate ictal events, the ictal sequences were predominantly composed

256 To properly resolve transmission events, these processes need to be taken into account.

257 studies in which rates of immediate adverse events to GBCAs were reported.

258 However, explicitly linking predation events to individual behaviour under natural conditions

259 trial (Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients).

260 ded clinical outcomes (major adverse cardiac events), use of healthcare resources, and impact on heal

261 greatest risk to experience an extreme cold event varied among years.

262 ase 3 trials), the most common local adverse events versus placebo within the first 14 days were arm

263 e annualized mortality rate after a bleeding event was 21.5 (95% CI, 15.4-29.1) per 100 person-years.

264 A severe critical event was defined as the occurrence of respiratory, card

265 increase in disability near the time of the event was greater for stroke (0.88 points on the disabil

266 The mean follow-up period for incident events was 12.5 years, from the year 15 computed tomogra

267 ho discontinued treatment because of adverse events was low (range, 0%-1%).

268 cations of interest and second breast cancer events was observed when surveillance was removed from o

269 Incidence of adverse events was similar for alirocumab versus control, except

270 Incidence of adverse events was similar in all groups (43 [88%] of 49 in the

271 The number of adverse events was similar regardless of immunisation status.

272 -frequency hearing loss, an expected adverse event, was documented in all participants.

273 d supplementation on clinical cardiovascular events, we update prior recommendations for patients wit

274 The most common serious adverse events were anaemia (eight [4%]), upper gastrointestinal

275 Serious adverse events were experienced by 35 (18%) patients in the olap

276 Treatment-related adverse events were generally grade 1 or 2 in severity.

277 Adverse events were generally mild (</= grade 2), with diarrhea

278 The most common adverse events were infective pulmonary exacerbations, cough, in

279 The most common isatuximab-related adverse events were infusion-associated reactions (IARs) (56%),

280 Data on adverse events were limited, but suggested an increased risk of

281 These events were linked to a decrease in the macrophage capac

282 Adverse events were more frequent with clindamycin (58 of 265 [2

283 thout airflow obstruction, acute respiratory events were not associated with additional FEV1 decline.

284 In this small study, no safety events were noted, but no safety conclusions can be draw

285 ewer grade 3 and 4 treatment-related adverse events were observed in patients on nivolumab (14% v 34%

286 Adverse events were rarely reported.

287 No severe adverse events were recorded.

288 Serious adverse events were reported in 56 (58%) eltrombopag-treated pat

289 s had grade 3 adverse events, but no grade 4 events were reported.

290 The binding events were studied by monitoring cyclic voltammetry sig

291 st frequently observed grade 3 and 4 adverse events were transaminase increases (40% alanine aminotra

292 Such a disruption induces a cascade of events which impacts glycan biosynthesis through Hexosam

293 Extreme summer temperature events - which are expected to occur with increasing fre

294 Safety was assessed on the basis of adverse events, which were graded according to the Common Termin

295 the synthesis of a protein to ensure that an event will occur at a precise time, while minimizing dev

296 Interventions that target these events will interrupt tuberculosis transmission and acce

297 analysis to detect individual vesicle fusion events with approximately 27 nm localization precision a

298 There was no increase in vascular occlusive events with tranexamic acid, with no heterogeneity by si

299 1.16] in the 10-14 d period following an SSO event, with positive ORs for all age groups and for thre

300 college and above], previous cardiovascular events [yes or no], current smoker [yes or no], and diab