ライフサイエンスコーパス: fission yeast

1 pt4 in controlling elongation in budding and fission yeast.

2 nesis functions of Cdc14/Flp1 in budding and fission yeast.

3 recent experiments on histone methylation in fission yeast.

4 sure proper splicing of certain pre-mRNAs in fission yeast.

5 ce a robust anti-stress cellular response in fission yeast.

6 tromeres cluster at the spindle pole body in fission yeast.

7 dscapes of the distantly related budding and fission yeast.

8 nd is a key determinant of cohesive sites in fission yeast.

9 stinct action of its GEFs, Gef1 and Scd1, in fission yeast.

10 reminiscent of natural polarity patterns in fission yeast.

11 novel protein, Rng10, during cytokinesis in fission yeast.

12 iations mediated by condensin and cohesin in fission yeast.

13 nd its relationship with the Rho-GAP Rga7 in fission yeast.

14 increased gamete death after IR is innate to fission yeast.

15 se, is essential for acetyl-CoA synthesis in fission yeast.

16 Rgf3 is an essential GEF for Rho1 GTPase in fission yeast.

17 n-mediated actin assembly for cytokinesis in fission yeast.

18 spindle disassembly in the closed mitosis of fission yeast.

19 o coordinate mitotic progression and exit in fission yeast.

20 acterize the transcriptome in the meiosis of fission yeast.

21 and constriction of the contractile ring in fission yeast.

22 report how cell growth domains are shaped in fission yeast.

23 ion to isolate variants that support life in fission yeast.

24 t are anticorrelated at the two cell tips in fission yeast.

25 hase and mitotic chromosomal organization in fission yeast.

26 es Rho4 GTPase as a Rho GEF for septation in fission yeast.

27 y is a hallmark of aneuploidy in budding and fission yeast.

28 tics tools used to study protein function in fission yeast.

29 on and unlocks the CRISPR toolset for use in fission yeast.

30 RNAs), suggesting that dsRNAs form widely in fission yeast.

31 n in regulating DSB repair pathway choice in fission yeast.

32 ion and influences cell cycle progression in fission yeast.

33 ption of an lncRNA governs drug tolerance in fission yeast.

34 in RNAi-directed heterochromatin assembly in fission yeast.

35 ded for uptake of extracellular phosphate in fission yeast.

36 e isoform level in the sexual development of fission yeast.

37 ic tubule elongation and vesicle scission in fission yeast.

38 physical mechanism for typical conditions in fission yeast.

39 subunit and, thereby, controls exocytosis in fission yeast.

40 function of PS in the rod-shaped, polarized fission yeast.

41 ner similar to what has been demonstrated in fission yeast.

42 are coordinated to maintain lipid balance in fission yeast.

43 3 act in parallel to inhibit TOR function in fission yeast.

44 ut are conspicuously absent from budding and fission yeasts.

45 se transcript landscapes between budding and fission yeasts.

46 which are absent or divergent in budding or fission yeasts.

47 In the closed mitosis of fission yeast, a microtubule-associated protein complex,

48 of this complexity, it is surprising that in fission yeast, a minimal Cdk network consisting of a sin

49 t during quiescence, the unicellular haploid fission yeast accumulates mutations as a linear function

50 Three 'killer genes' in one species of fission yeast act selfishly and keep it reproductively i

51 The fission yeast actin cytoskeleton is an ideal, simplified

52 Here, we develop a strategy for loading the fission yeast Ago1 with a single-stranded sRNA guide, wh

53 Whereas in fission yeast all kinetochores relaxed to a similar leng

54 ivity and resistance conferring mutations in fission yeast, along with biochemical assays with recomb

55 Fission yeast AMPK catalytic subunit Ssp2 is phosphoryla

56 A similar response can be observed in fission yeast and bacteria.

57 and regulatory basis of energy metabolism in fission yeast and beyond, and it pinpoints weaknesses of

58 ere spatially organized by eisosomes in both fission yeast and budding yeast cells.

59 -based systems analysis of CDK substrates in fission yeast and demonstrate that the phosphorylation o

60 We purified both fission yeast and human Aip1 and investigated their bioc

61 fic manner in Schizosaccharomyces pombe Both fission yeast and human Sde2 are translated as inactive

62 Fission yeast and mammalian Rif1 proteins have also been

63 irth of synthetic centromeres in budding and fission yeast and mammals.

64 s with sensitivity to DNA-damaging agents in fission yeast and reduced viability in human cells.

65 led previously undetected origin clusters in fission yeast and shows that in human cells replication

66 r target recognition in the TORC2 complex in fission yeast and the mTORC2 complex in mammals.

67 ed up to the length of entire chromosomes in fission yeast and up to 12 Mb fragments in human cells.

68 studies of Cdc42 polarization in budding and fission yeasts and demonstrate that models describing sy

69 confidence SUMO-modified target proteins in fission yeast, and a robust method for future analyses o

70 pe in mammals, spindle pole body dynamics in fission yeast, and surveillance of defective nuclear por

71 nderstand the mechanism of cytokinesis using fission yeast as a favorable model system.

72 Using fission yeast as a model, we report here that DBAN delay

73 oles of GR in cellular stress response using fission yeast as a model.We surprisingly discovered mark

74 motes epigenetic stability of centromeres in fission yeast, at least in part via recruitment of the C

75 ere we present a mechanism for aneuploidy in fission yeast based on spindle pole microtubule defocusi

76 found previously that upon disruption of the fission yeast bouquet, centrosomes failed to insert into

77 ve species-specific network rewiring between fission yeast, budding yeast, and human.

78 rtholog) are required for both activities in fission yeast but whether they are genetically separable

79 points contributes to kinetochore capture in fission yeast, but the relative contributions of dynamic

80 daptor Nro1 regulate the hypoxic response in fission yeast by controlling activity of the sterol regu

81 We report here that Rga6 is another fission yeast Cdc42 GAP which shares some functions with

82 only GAP described as negative regulator of fission yeast Cdc42.

83 Using fission yeast cell cycle as an example, we uncovered tha

84 g the stability, speed and robustness of the fission yeast cell cycle oscillations.

85 equentiality, as observed in the budding and fission yeast cell- cycle.

86 In further investigations of the budding and fission yeast cell-cycle, we identify two generic dynami

87 opy (FPALM), we probed this question in live fission yeast cells at unprecedented resolution.

88 s required for oxidative stress responses in fission yeast cells by promoting transcription initiatio

89 Here, we show that fission yeast cells carrying a mutation in the DNA-bindi

90 We show that fission yeast cells deficient in ER-PM contacts exhibit

91 Cytokinesis in fission yeast cells depends on conventional myosin-II (M

92 We study cell polarization when fission yeast cells exit starvation.

93 inuous replication of hundreds of individual fission yeast cells for over seventy-five generations.

94 Rod-shaped fission yeast cells grow in a highly polarized manner, a

95 Using fission yeast cells lacking the debranching enzyme Dbr1,

96 erresolution localization microscopy of live fission yeast cells to improve the spatial resolution to

97 Fission yeast cells use Arp2/3 complex and formin to ass

98 In this issue, Dudin et al. image mating fission yeast cells with unprecedented spatiotemporal re

99 In fission yeast cells, a microtubule-dependent network has

100 which distributes homogeneously in wild-type fission yeast cells, can be made to concentrate at cell

101 In fission yeast cells, the formin Fus1, which nucleates li

102 okinesis nodes and contractile rings in live fission yeast cells.

103 Here, we employ the well-studied fission yeast centromere [13-16] to investigate the func

104 ton and cytoskeleton (LINC) complex connects fission yeast centromeres and the centrosome, across the

105 to contribute to heterochromatin assembly at fission yeast centromeres.

106 lectable kanMX reporter gene embedded within fission yeast centromeric heterochromatin.

107 g genome-wide methods, here we show that the fission yeast CID-protein Seb1 is essential for terminat

108 Here, we show that fission yeast Cki3 (a casein kinase 1gamma homolog) is a

109 In this work, we use fission yeast co-expression networks before and after ex

110 tute cohesin loading onto DNA using purified fission yeast cohesin and its loader complex, Mis4(Scc2)

111 Using biochemical analysis of fission-yeast cohesin, we find that a similar series of

112 PomBase provides a central hub for the fission yeast community, supporting both exploratory and

113 similar structures appear to be conserved in fission yeast, computational modeling and analysis of hi

114 The fission yeast contractile ring has been proposed to asse

115 Using in vitro reconstitution of fission yeast contractile ring precursor nodes containin

116 ly analyse the requirements of the different fission yeast cyclins for meiotic cell cycle progression

117 ivered by myosin-V on linear actin cables in fission yeast cytokinesis.

118 in turn modulates active Rho1 levels during fission yeast cytokinesis.

119 In fission yeast, cytokinesis involves the type II myosins

120 icient contractile ring assembly in vivo.The fission yeast cytokinetic ring assembles by Search-Captu

121 rchers, to support community curation in the fission yeast database, PomBase.

122 a GFP-based protein reporter and screened a fission yeast deletion collection using flow cytometry.

123 l to analyze these results, we conclude that fission yeast does not age and that cellular aging and r

124 The related SHREC complex in fission yeast drives transcriptional gene silencing in h

125 The fission yeast Dsc E3 ligase is a Golgi-localized complex

126 In the absence of mga2, fission yeast exhibited growth defects under both normox

127 hat during transcriptional activation of the fission yeast fbp1 gene, binding of Rst2 (a critical C2H

128 In fission yeast, force balance is restored when both kines

129 d facultative heterochromatin islands in the fission yeast genome and found that RNA elimination mach

130 The fission yeast genome, which contains numerous short intr

131 Micro-C XL maps of budding and fission yeast genomes capture both short-range chromosom

132 In fission yeast, glucose starvation triggers lncRNA transc

133 Fission yeast GTase binds the Spt5 CTD at a separate doc

134 Fission yeast has a single H3K9 methyltransferase, Clr4,

135 The anaphase B spindle in fission yeast has a slender morphology and must elongate

136 Using the fission yeast, here, we track G0-associated chromatin an

137 ith each other in vitro, and at least in the fission yeast, heterologous Oxs1 and Pap1-homologues can

138 In fission yeast, histone H3 lysine 9 (H3K9) is methylated

139 Erh1, the fission yeast homolog of Enhancer of rudimentary, is imp

140 Here, we identify Fft3, a fission yeast homolog of the mammalian SMARCAD1 SNF2 chr

141 of the SMN.Gemin2 complexes from humans and fission yeast (hSMN.Gemin2 and ySMN.Gemin2).

142 d mitogen activated protein kinase (MAPK) in fission yeast, inhibits TORC2-dependent Gad8 phosphoryla

143 Here we show that in fission yeast, introducing the K9M mutation into one of

144 t early divergence from a common ancestor in fission yeast involved important changes in the mechanis

145 Like budding yeast, fission yeast is an important and popular model organism

146 is type of non-canonical fork convergence in fission yeast is prone to trigger deletions between repe

147 hods also show that the number of patches in fission yeast is proportional to cell length and that th

148 Mer2, identified so far only in budding and fission yeasts, is in fact evolutionarily conserved from

149 However, in fission yeast it has been shown that a single CDK comple

150 s effective in predicting the DNA content of fission yeast, it is likely to have a broad application

151 JMJ24 functionally resembles the fission yeast JmjC protein Epe1.

152 hanism underlying nuclear congression during fission yeast karyogamy upon mating of haploid cells.

153 for the bidirectional motility mechanism of fission yeast kinesin-5 and provide insight into the fun

154 s, we studied the effects of deletion of the fission yeast kinesin-8 proteins Klp5 and Klp6 on chromo

155 Fission yeast lacking Aip1 are viable and assemble cytok

156 In fission yeast lacking Nup132 (Sc/HuNUP133), Ulp1 is delo

157 fork blockage at a site-specific barrier in fission yeast, leading to a restarted fork within approx

158 Here, we describe a multiplexed fission yeast lifespan micro-dissector (multFYLM) and an

159 Myo51, a class V myosin in fission yeast, localizes to and assists in the assembly

160 Here, we show that insertion of the fission yeast LTR retrotransposon Tf1 is guided by the D

161 rminant of chromosome segregation defects in fission yeast may be microtubule dynamic defects.

162 In fission yeast, Mcp5 is the anchor protein of dynein and

163 In fission yeast, medial division is controlled through neg

164 In fission yeast, meiosis-specific transcripts are selectiv

165 In contrast, distinct pathways activate fission yeast Mga2 and Sre1.

166 n telomere dispersion and disjunction during fission yeast mitosis.

167 chromosome territories are organized in the fission yeast model organism.

168 We analyze a fission yeast mutant that is unable to complete S phase

169 we analyzed the poly(A)(+) transcriptomes of fission yeast mutants that lack each of the four inessen

170 , we discovered that the myosin I protein in fission yeast, Myo1, which is required for organization

171 r previous work suggested, however, that the fission yeast myosin-V (Myo52p) is a nonprocessive motor

172 In fission yeast, nitrogen stress results in sustained prol

173 ysical model of kinetochore capture in small fission-yeast nuclei using hybrid Brownian dynamics/kine

174 the degradation pathways for Sdj1-L169P, the fission yeast orthologue of the disease-causing DJ-1 L16

175 suggests a mechanistic conservation between fission yeast PAF1 repressing AGO1/small interfering RNA

176 hat the greatwall-endosulfine (Ppk18-Igo1 in fission yeast) pathway couples the nutritional environme

177 The fission yeast plasma membrane is highly compartmentalize

178 Besides the Cdk7 ortholog Mcs6, fission yeast possesses a second CAK, Csk1.

179 ing yeast profilin ScPFY fails to complement fission yeast profilin SpPRF temperature-sensitive mutan

180 A new study in fission yeasts promotes the notion that transient polari

181 Here, we identify the fission yeast protein Sdj1 as the orthologue of DJ-1 and

182 To isolate ring mechanisms, we studied fission yeast protoplasts, in which constriction occurs

183 As a model for cellular energy regulation, fission yeast provides an attractive and complementary s

184 This analysis of H3-G34R mutant fission yeast provides mechanistic insight into how G34R

185 parts list of genes important for meiosis in fission yeast, providing a valuable resource to advance

186 Fission yeast Rec12 (Spo11 homolog) initiates meiotic re

187 ed Mst2 histone acetyltransferase complex in fission yeast regulates histone turnover at heterochroma

188 Here, we identify new fission yeast regulatory lncRNAs that are targeted, at t

189 The growth of fission yeast relies on the polymerization of actin fila

190 Unlike S. pombe, two other fission yeasts rely on hyperstabilization of the U6 snRN

191 viding a brief description of the origins of fission yeast research, and illustrating some genetic an

192 in inhibitors Sml1p and Spd1p in budding and fission yeast, respectively.

193 y, a superresolution microscopy study of the fission yeast ring revealed that myosins and formins tha

194 Thus, the fission yeast ring sets its own tension, but other proce

195 e a coarse-grained mathematical model of the fission yeast ring to explore essential consequences of

196 In fission yeast, RNAi machinery and RNA elimination factor

197 Using a genome-wide approach in the fission yeast S. pombe, we have found that Dcr1, but not

198 We examine the function of Swi1 and Swi3, fission yeast's primary FPC components, to elucidate how

199 The fission yeast scaffold molecule Sid4 anchors the septum

200 oes not position the cytokinetic ring in the fission yeast Schizosaccharomyces japonicus, unlike its

201 nce, RNAi, are broadly conserved between the fission yeast Schizosaccharomyces pombe and humans.

202 Fission yeast Schizosaccharomyces pombe are rod-shaped c

203 Here we use the fission yeast Schizosaccharomyces pombe as a model to in

204 cts of turgor pressure on endocytosis in the fission yeast Schizosaccharomyces pombe by time-lapse im

205 In rod-shaped fission yeast Schizosaccharomyces pombe cells, division

206 ant and popular model organism; however, the fission yeast Schizosaccharomyces pombe community curren

207 quest to understand the morphogenesis of the fission yeast Schizosaccharomyces pombe drove us to inve

208 This also occurs in Smc5/6 hypomorphs in the fission yeast Schizosaccharomyces pombe following genoto

209 ean laboratories in the 1940s and 1950s, the fission yeast Schizosaccharomyces pombe has grown to bec

210 The fission yeast Schizosaccharomyces pombe has six Rho GTPa

211 Studies in fission yeast Schizosaccharomyces pombe have provided th

212 Here, using Clr4, the fission yeast Schizosaccharomyces pombe homologue of mam

213 e oxygen-responsive lipid homeostasis in the fission yeast Schizosaccharomyces pombe in a manner anal

214 The fission yeast Schizosaccharomyces pombe is an important

215 The fission yeast Schizosaccharomyces pombe is an important

216 Heterochromatin in the fission yeast Schizosaccharomyces pombe is clustered at

217 We recently showed that drug tolerance in fission yeast Schizosaccharomyces pombe is controlled by

218 re we present evidence that cell size in the fission yeast Schizosaccharomyces pombe is regulated by

219 how that inhibition of Arp2/3 complex in the fission yeast Schizosaccharomyces pombe not only deplete

220 The two PKC orthologs Pck1 and Pck2 in the fission yeast Schizosaccharomyces pombe operate in a red

221 Fission yeast Schizosaccharomyces pombe P and M cells, w

222 In the fission yeast Schizosaccharomyces pombe proteins that co

223 ory element-binding proteins (SREBPs) in the fission yeast Schizosaccharomyces pombe regulate lipid h

224 ted OSPW was significantly less toxic to the fission yeast Schizosaccharomyces pombe than unstimulate

225 viously described a mutant, pat1-as2, of the fission yeast Schizosaccharomyces pombe that undergoes s

226 sue we performed ribosome profiling with the fission yeast Schizosaccharomyces pombe under conditions

227 The fission yeast Schizosaccharomyces pombe undergoes "close

228 In the fission yeast Schizosaccharomyces pombe, active Cdc42 an

229 Recent findings show that in the fission yeast Schizosaccharomyces pombe, cleavage furrow

230 In the fission yeast Schizosaccharomyces pombe, conserved prote

231 During mitosis in fission yeast Schizosaccharomyces pombe, cytoplasmic mic

232 Here we show that, in the fission yeast Schizosaccharomyces pombe, ectopically ind

233 In both mammalian PtK1 cells and in the fission yeast Schizosaccharomyces pombe, kinetochores sh

234 In the fission yeast Schizosaccharomyces pombe, the CaMKK-like

235 In the fission yeast Schizosaccharomyces pombe, the multi-BRCT

236 In the fission yeast Schizosaccharomyces pombe, the protein kin

237 In the fission yeast Schizosaccharomyces pombe, the SREBP-2 hom

238 The single family member expressed in the fission yeast Schizosaccharomyces pombe, Zfs1, promotes

239 study mitotic chromosome condensation in the fission yeast Schizosaccharomyces pombe.

240 motion of direct repeat recombination in the fission yeast Schizosaccharomyces pombe.

241 w mitotic transcription factor, Sak1, in the fission yeast Schizosaccharomyces pombe.

242 l conditions including osmotic stress in the fission yeast Schizosaccharomyces pombe.

243 is essential for telomere maintenance in the fission yeast Schizosaccharomyces pombe.

244 distinct from that found specifically in the fission yeast Schizosaccharomyces pombe.

245 transcriptional histone modifications in the fission yeast Schizosaccharomyces pombe.

246 dding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe.

247 rgely independent of Set1C and H3K4me in the fission yeast Schizosaccharomyces pombe.

248 for induction of synchronous meiosis in the fission yeast Schizosaccharomyces pombe.

249 f meiotic drive genes on chromosome 3 of the fission yeasts Schizosaccharomyces kambucha and S. pombe

250 NE management strategies between the related fission yeasts Schizosaccharomyces pombe and Schizosacch

251 e plasticity of division site positioning in fission yeasts Schizosaccharomyces pombe and Schizosacch

252 he most dramatic shift in gene expression in fission yeast (Schizosaccharomyces pombe), and this resp

253 lyze RNA-seq data from 116 transcriptomes in fission yeast (Schizosaccharomyces pombe), covering mult

254 atalog of genes important for meiosis in the fission yeast, Schizosaccharomyces pombe Our genome-wide

255 Meiotic chromosome movements in the fission yeast, Schizosaccharomyces pombe, depend on astr

256 In fission yeast, Schizosaccharomyces pombe, interactions b

257 In fission yeast, Scm3sp and the Mis18 complex, composed of

258 Similar to the human shelterin, fission yeast shelterin is composed of telomeric sequenc

259 Elimination of the fission yeast shelterin subunit Ccq1 causes progressive

260 In fission yeast, shelterin is comprised of five proteins.

261 In contrast, previous work with budding and fission yeast showed that some outer kinetochore protein

262 ypotheses, yielding additional evidence that fission yeast siRNA-Argonaute silencing complexes are re

263 inding mutant shows a reduced association of fission yeast SMC5/6 with chromatin.

264 putative chromatin remodeling subunit of the fission yeast Snf2/histone deacetylase (HDAC) repressor

265 The fission yeast specific chaperone Rng3 was thus not requi

266 Proteolytic release of fission yeast SREBPs from the membrane in response to lo

267 genic suppressors of a temperature-sensitive fission yeast strain mutated in the exocyst subunit Sec3

268 Here we show that the fission yeast stress-activated protein kinase Sty1, a ho

269 coupled with mass spectrometry, to identify fission yeast SUMO conjugates.

270 Therefore, knowledge from the budding and fission yeast systems illuminates highly conserved molec

271 In fission yeast, Tel1(ATM)/Rad3(ATR)-mediated phosphorylat

272 In fission yeast, telomerase is recruited through an intera

273 p1, an uncharacterized NAP family protein in fission yeast that antagonizes CENP-A loading at both ce

274 sight into the role of H3-G34R, we generated fission yeast that express only the mutant histone H3.

275 We show in fission yeast that, at low Cdc20 concentrations, Cdc20(M

276 In fission yeast, the conserved telomeric shelterin complex

277 In fission yeast, the kinesin-14 Pkl1 binds the gamma-tubul

278 In fission yeast, the Rpa1-D223Y mutation provokes telomere

279 In fission yeast, the ste11 gene encodes the master regulat

280 Here we address these questions in fission yeast through proteome-wide analyses of SUMO mod

281 Here we show that Tts1, the fission yeast TMEM33 protein that was previously implica

282 , showing tetrameric Mis18 is conserved from fission yeast to humans.

283 We screened deletion libraries of fission yeast to identify over 200 genes required for re

284 ools to track and count endocytic patches in fission yeast to increase the quality of the data extrac

285 Here, we use fission yeast to investigate how phosphatase activity pa

286 and FPALM superresolution microscopy of live fission yeast to investigate the structures and assembly

287 From fission yeast to mammals, heterochromatin assembly at DN

288 In fission yeast, TORC2 is dispensable for proliferation un

289 In fission yeast, TORC2 is dispensable for proliferation un

290 Here, we report the crystal structure of the fission yeast Tpz1(475-508)-Poz1-Rap1(467-496) complex t

291 The Schizosaccharomyces pombe fission yeast Tup family corepressors Tup11 and Tup12 (T

292 mic bundling is important for cytokinesis in fission yeast, we created the less dynamic bundling muta

293 Here using fission yeast, we identify Fun30(Fft3) as a chromatin re

294 Using fission yeast, we report the first genome-wide analysis

295 To characterize R-loops in fission yeast, we used the S9.6 antibody-based DRIPc-seq

296 l1p, the main eisosome BAR-domain protein in fission yeast, we visualized whole eisosomes and, after

297 ibe a functional fluorescent Cdc42 allele in fission yeast, which demonstrates Cdc42 dynamics and pol

298 cytokinesis arrest in the erg11-1 mutant of fission yeast, which has a partial defect in the biosynt

299 rding the human gene homologs in budding and fission yeast, worm, fly, fish, mouse, and rat on a sing

300 antified the localization pattern of Mcp5 in fission yeast zygotes and show by perturbation of phosph