ライフサイエンスコーパス: gene insertion

1 iliated Hib or to a mutant containing a hifE gene insertion.

2 insertion sequence elements or phage-related gene insertions.

3 egregation of mutations, edits, and targeted gene insertions.

4 us), whereas sorghum received two additional gene insertions after its divergence from a common ances

5 The rate of gene insertion and deletion is sufficiently high in thes

6 ci we find ancestral alleles, which lack the gene insertions and exhibit high levels of nucleotide po

7 nces, an apparent plasmid hot spot for toxin gene insertion, and that two IS1151-related sequences ar

8 The results suggest that the RSV F and G gene insertions are stable in the PIV5 genome.

9 site, were demonstrated to generate precise gene insertions as well as indel mutations at the target

10 /Cas9 knockin system allows highly efficient gene insertion at the pH11 locus of up to 54% using drug

11 y-directed and homology-independent targeted gene insertion at the ZFN-specified locus.

12 us (AAV) donor vectors enables site-specific gene insertion by homology-directed genome editing.

13 support this by showing that single-stranded gene insertion cassettes are recombinogenic and that the

14 ave rise to sorghum and maize acquired a two-gene insertion (containing the adh locus), whereas sorgh

15 tween homeologous regions with only a single gene insertion/deletion and local tandem duplications di

16 his study tested the hypothesis that the ACE gene insertion/deletion polymorphism associates with AF

17 The angiotensin-converting enzyme (ACE) gene insertion/deletion polymorphism influences ACE acti

18 ACE gene insertion/deletion polymorphism was determined by p

19 n Escherichia coli by use of a plasmid-based gene insertion/deletion system.

20 s including not only rearrangements but also gene insertions, deletions and duplications.

21 (MLEs) of the new model reveal fast rates of gene insertions/deletions on recent branches, suggesting

22 irus-based vectors include gene replacement, gene insertion, epitope presentation, use of virus contr

23 reduction n AC activity, confirming that the gene insertion event disrupted AC activity and ceramide

24 ctivated by a discrete, approximately 4.7 kb gene insertion event that disrupted the 3' end of the BR

25 lines was characterized in terms of foreign gene insertion, expression of spinach SPS, production of

26 f site-specific nucleases yielded consistent gene insertion frequencies of 2-3%, similar to tradition

27 rrier proteins can be attributed to a single gene insertion in Acyl Carrier Protein4 (At4g25050).

28 E system offers rapid, efficient and precise gene insertion in ESC and iPSC and is particularly well

29 estigate whether TnsA-D proteins can mediate gene insertion into comparably conserved sites in eukary

30 safety considerations regarding transposase gene insertions into host genomes have rarely been addre

31 Thus, Cas9-mediated suicide-gene insertion may be a viable genotype-specific cancer

32 However, the function of the foreign gene insertion may need to be considered when designing

33 eport, we evaluated the spectrum of protease gene insertion mutations in patient isolates and analyze

34 evealed two mutations in the epsilon-subunit gene: insertion of a thymine after epsilon nucleotide 11

35 simultaneous expression of multiple foreign genes, insertion of noncoding/antisense sequences, and s

36 We studied the association between the ACE gene insertion or deletion polymorphism and changes in b

37 would enable higher efficiencies of precise gene insertion or replacement, we screened the Cpf1 nucl

38 T cells by T cell subset selection, suicide gene insertion or selective allodepletion, and the adopt

39 the frequency of genomic rearrangements and gene insertions or deletions was relatively low.

40 hibition might result from pgk-neor cassette gene insertion rather than enhancer deletion.

41 exhibiting targeted mutagenesis or targeted gene insertion, respectively.

42 This gene insertion results in the synthesis of an exon 3-del

43 system by using gene replacement rather than gene insertion technology.

44 s direct selection for gene replacements and gene insertions that can facilitate this process.

45 g the possibility to couple tmIgE with other gene insertions that might enhance the antitumor effect,

46 ibe ObLiGaRe, a new method for site-specific gene insertions that uses the efficient NHEJ pathway and

47 An H gene insertion vector has been generated from the Edmons

48 2006 for their capability to induce targeted gene insertion via homology directed repair.

49 We found that VSVs with a double gene insertion were significantly more attenuated than V