ライフサイエンスコーパス: glycolytic pathway

1 oglycerate mutase (PGAM)-B, an enzyme of the glycolytic pathway.

2 loning and shown to encode an enolase in the glycolytic pathway.

3 the muscle and enhanced the activity of the glycolytic pathway.

4 resence of pharmacological inhibition of the glycolytic pathway.

5 lent metals play a role in regulation of the glycolytic pathway.

6 th a multilocus response to selection in the glycolytic pathway.

7 A clone coded for aldolase, an enzyme of the glycolytic pathway.

8 crease the levels of enzymes involved in the glycolytic pathway.

9 protein, which plays a critical role in the glycolytic pathway.

10 ng competitive inhibitor of an enzyme in the glycolytic pathway.

11 component of the gluconeogenic branch of the glycolytic pathway.

12 ctions with YPK and in the regulation of the glycolytic pathway.

13 ated for by appropriate up-regulation of the glycolytic pathway.

14 portant role in cells that require an active glycolytic pathway.

15 K2), one of the rate-limiting enzymes of the glycolytic pathway.

16 sphofructokinase, an important enzyme in the glycolytic pathway.

17 ed the glutaminolytic pathway instead of the glycolytic pathway.

18 an enzyme normally designed to terminate the glycolytic pathway.

19 on that diverts serine biosynthesis from the glycolytic pathway.

20 in glucose uptake and metabolism through the glycolytic pathway.

21 the canonical Embden-Meyerhoff-Parnass (EMP) glycolytic pathway.

22 APDH) is a ubiquitous enzyme involved in the glycolytic pathway.

23 (NAD(+)) pool for continuous fueling of the glycolytic pathway.

24 splays enzymatic activities intrinsic to the glycolytic pathway.

25 or several glycolytic enzymes throughout the glycolytic pathway.

26 sphate (G6P), which is the first step in the glycolytic pathway.

27 le and enhanced pyruvate shunting toward the glycolytic pathway.

28 th associated increased glucose flux through glycolytic pathway.

29 used Adh(A) to recycle NADH generated in the glycolytic pathway.

30 o be a mechanism for compartmentation of the glycolytic pathway.

31 ATP generation in the terminal stage of the glycolytic pathway.

32 e between the utilization of respiratory and glycolytic pathways.

33 gy conversion away from oxidative and toward glycolytic pathways.

34 catalytic activity of two key enzymes in the glycolytic pathway, 6-phosphofructokinase and pyruvate k

35 hat the members of this lineage use in their glycolytic pathway a GAPDH species with properties and a

36 rains whose growth depended on two nonnative glycolytic pathways: a complete glycolysis from the rela

37 ium lactate, which bypasses the block in the glycolytic pathway, abolished the anticonvulsant activit

38 Loss of BT3172 reduces glycolytic pathway activity in vitro and in vivo.

39 of carbon flux through the gluconeogenic and glycolytic pathways, also stimulated glucose-6-phosphata

40 important transcriptional activators of the glycolytic pathway and contribute to the Warburg effect

41 ypoxia, including increased flux through the glycolytic pathway and decreased flux through the tricar

42 However,Mtbalso maintains a functional glycolytic pathway and its role in the cellular metaboli

43 xisomes that uniquely contain enzymes of the glycolytic pathway and other parts of intermediary metab

44 ch have come to compartmentalize most of the glycolytic pathway and play a role in developmental sign

45 Malignant cancer cells use the glycolytic pathway and require MCTs to efflux lactate th

46 nfluences metabolism via upregulation of the glycolytic pathway and suppression of mitochondrial resp

47 an enhanced flux of glucose through both the glycolytic pathway and the hexose monophosphate shunt.

48 changes in the level of intermediates in the glycolytic pathway and the ratios of ATP/ADP and NAD(P)H

49 e-grown cells that are unique to the unusual glycolytic pathway and three in peptide-grown cells that

50 We introduce modifications in glycolytic pathways and the Calvin Benson cycle to incre

51 as supported by silencing other genes in the glycolytic pathway, and confirmed by observation of a si

52 DENV activates the glycolytic pathway, and inhibition of glycolysis signifi

53 1) We are still missing key enzymes from the glycolytic pathway, and the conjecture is that this is d

54 port chain, in which adjacent enzymes in the glycolytic pathway are assembled to permit efficient flu

55 surprising discovery that components of the glycolytic pathway are enriched on the apoptotic cell su

56 ycerol, which interfaces with the glycosomal glycolytic pathway, are also toxic during PEX14 RNAi.

57 rrelation plots between metabolites from the glycolytic pathway, as well as with the observed ATP/ADP

58 PGM plays a central role in the glycolytic pathway at the branch point leading to glycog

59 hysical basis for plasma membrane-associated glycolytic pathway been established.

60 cells maintain largely normal fluxes through glycolytic pathways, but the entire output of these path

61 colysis, catalyses the committed step of the glycolytic pathway by converting fructose-6-phosphate to

62 This discovery reveals that the glycolytic pathway can bypass the formation of 3-phospho

63 The glycolytic pathway, comprising aldehyde dehydrogenase (A

64 ic isoenzymes by any alternative, functional glycolytic pathway configuration.

65 further show that prokaryotes use different glycolytic pathways depending on their energy supply.

66 hese included putative genes involved in the glycolytic pathway, DNA, RNA, and protein metabolism, an

67 tion of oxygen tension, Hb conformation, and glycolytic pathway dominance.

68 Pharmacologically inhibiting the glycolytic pathway dramatically reduced DENV RNA synthes

69 e (YPK) is regulated by intermediates of the glycolytic pathway [e.g., phosphoenolpyruvate (PEP), fru

70 ate shuttle and/or the distal portion of the glycolytic pathway, either of which can lead to producti

71 s a protein that is highly homologous to the glycolytic pathway enzyme, Pgm.

72 fructose-1,6-bisphosphate aldolases (FBPA), glycolytic pathway enzymes, exhibit no amino acid sequen

73 ression of cancerous cells by enabling their glycolytic pathways even under severe hypoxic conditions

74 the increased dependence of cancer cells on glycolytic pathway for ATP generation provides a biochem

75 en microenvironment and actively utilize the glycolytic pathway for ATP generation.

76 linal variation is common for enzymes in the glycolytic pathway for Drosophila melanogaster and is ge

77 Most of these species rely on the glycolytic pathway for energy production, with the one e

78 their increased reliance on the inefficient glycolytic pathway for energy production.

79 r-Doudoroff pathway rather than the standard glycolytic pathway for glucose catabolism, and anaplerot

80 Targeting the glycolytic pathway for the treatment of hematological ma

81 is asaccharolytic because it lacks an active glycolytic pathway for the use of sugars as a carbon sou

82 e 2-epimerase (NanE) belongs to a convergent glycolytic pathway for utilization of the three amino su

83 inhibited HIF-1alpha, showed upregulation of glycolytic pathway genes, glucose transporter 1-4 (Glut1

84 rgeting down-regulated expression of several glycolytic pathway genes, with a corresponding decrease

85 The genes encoding three enzymes of the glycolytic pathway have been identified and sequenced co

86 ing allostery or key regulatory nodes in the glycolytic pathway impacted the size of the outer segmen

87 st localization of the upstream steps of the glycolytic pathway in Chlamydomonas.

88 ext by 'predicting' the intermediates in the glycolytic pathway in Escherichia coli.

89 s gives clear insight into this exchange for glycolytic pathway in human red blood cell, including th

90 The importance of the glycolytic pathway in invasion and plaque formation was

91 on and functional levels and a switch to the glycolytic pathway in mphis, while IL-4-treated mphis ut

92 demonstrate the cell autonomous role of the glycolytic pathway in outer segment maintenance and prov

93 Up-regulation of the anaerobic glycolytic pathway in the muscle of fast-growing fish wa

94 specifically produced by a compartmentalized glycolytic pathway in the principal piece of the flagell

95 abundant components and extensive study, the glycolytic pathway in the yeast Saccharomyces cerevisiae

96 erences in flux through the lower end of the glycolytic pathway in this stage.

97 ct between the histidine decarboxylation and glycolytic pathways in acid stress survival.

98 several species--controls the gluconeogenic/glycolytic pathways in liver in response to fasting sign

99 y and decreased allosteric regulation by the glycolytic pathway intermediate fructose 1,6-bisphosphat

100 spontaneous formation of methylglyoxal from glycolytic pathway intermediates.

101 The glycolytic pathway is a potential therapeutic target to

102 We report that the glycolytic pathway is actively regulated during the diff

103 Regulation of the glycolytic pathway is considered to be primarily achieve

104 functional evidence that the ATP-generating glycolytic pathway is directly coupled to the ATP-hydrol

105 esults imply that metabolic flux through the glycolytic pathway is reduced in diabetes.

106 eoxy-d-glucose, indicating that a functional glycolytic pathway is required for this protective effec

107 r, previous studies indicated that an active glycolytic pathway is required to achieve normal sperm f

108 the Entner-Doudoroff and the DeLey-Doudoroff glycolytic pathways is described.

109 rotein abundance for carbon assimilatory and glycolytic pathways leading to fatty acid synthesis in r

110 replenished through the very ATP-inefficient glycolytic pathway; macrocyclic polyamines appear to be

111 s identity as a key regulatory enzyme in the glycolytic pathway, namely phosphofructokinase-M (PFK-M)

112 creased and 20 decreased) clustered into the glycolytic pathway, nucleotide sugars, intermediates of

113 Enzymes in the glycolytic pathway of mammalian sperm are modified exten

114 e activity for reconstitution of the defunct glycolytic pathway of the bacterial auxotroph.

115 somerase (GPI), the first two enzymes of the glycolytic pathway of the diplomonads Giardia intestinal

116 The glycolytic pathway of these organisms resides within the

117 -1-phosphate, which then feed into the novel glycolytic pathway of this organism.

118 studies demonstrate that HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint f

119 ting increase in abundance of enzymes in the glycolytic pathway (pentose phosphate and pyruvate metab

120 Thus, telomerase activity controls the glycolytic pathway, potentially altering the energy stat

121 n in these bacteria limits conversion of the glycolytic pathway product phosphoenolpyruvate to the tr

122 t the method can detect intermediates of the glycolytic pathway, quantify their rate of formation, an

123 ive genes encode for critical enzymes in the glycolytic pathway, revealing how CD44 could be a gateke

124 al biochemical networks, including microbial glycolytic pathways, signal transduction pathways and re

125 TP and higher utilization of glucose via the glycolytic pathway than ECV304 cells.

126 lation of PGAM1 and may provide an alternate glycolytic pathway that decouples adenosine triphosphate

127 tabolic processes within the cells, both the glycolytic pathway that produces ATP and the cellular pr

128 tionalization in this organism of an unusual glycolytic pathway that was previously thought not to co

129 ncapable of performing the first step of the glycolytic pathway, the phosphorylation of glucose.

130 larly diverse, including several alternative glycolytic pathways, the most common of which is the Ent

131 e expression of hexokinase-ll (HK-II) in the glycolytic pathway through elevated c-MYC.

132 ts demonstrate that Rho GTPases regulate the glycolytic pathway through Pak and suggest a link betwee

133 ve traditionally been thought to rely on the glycolytic pathway to generate ATP, recent studies sugge

134 dvance our understanding of how to block the glycolytic pathway to inhibit tumor progression by using

135 se experiments suggest that DENV induces the glycolytic pathway to support efficient viral replicatio

136 responsible for localizing components of the glycolytic pathway to the fibrous sheath and that this l

137 To assess enzyme-specific control in the glycolytic pathway, we used P-element excision-derived m

138 sole enzyme linking hexosamine systems with glycolytic pathways, we propose that it provides a sourc

139 th a highly efficient pyrophosphate-mediated glycolytic pathway, which under oxygen limitation partic

140 This enzyme equips the glycolytic pathway with a special steering function for

141 phoenolpyruvate utilization and connects the glycolytic pathway with the TCA cycle, restored CFA to r