ライフサイエンスコーパス: histologic

1 increased vascular permeability, and induced histologic ALI in naive mice.

2 er infection, and inflammatory responses and histologic alterations were analyzed.

3 Results Histologic alterations were detected in 44% (11 of 25) o

4 Molecular, cellular, and histologic analyses demonstrated a close alignment betwe

5 Histologic analyses of four matrix proteins-collagen I a

6 In histologic analyses of gastric resection specimens from

7 e determined using metabolic chambers and by histologic analyses of liver tissues.

8 MPO protein and activity measurements and histologic analyses were performed.

9 Electron microscopy, histologic analyses, and immunoblotting were used to det

10 Immune response was tested by histologic analyses.

11 sults from serology tests, and findings from histologic analyses.

12 gree of fibrofatty myocardial replacement at histologic analysis (r = -0.75, P = .017).

13 as subsequently measured ex vivo by means of histologic analysis and hydroxyproline assay.

14 Similarly, histologic analysis demonstrated no difference in collag

15 Histologic analysis demonstrated that lesion location wa

16 Histologic analysis of adult male brains identified a si

17 l mice (P < 0.001), in good correlation with histologic analysis of apoptosis (CC3, r = 0.842, and TU

18 grades and changes in hepatic steatosis when histologic analysis of biopsies is used as a reference.

19 f UCNPs@mSiO2, cellular live/dead assay, and histologic analysis of main organs of treated mice, reve

20 Histologic analysis of the allograft biopsy specimen is

21 After histologic analysis of the bone marrow biopsy specimen,

22 Histologic analysis showed absent to low-grade inflammat

23 mutations across regions that were found via histologic analysis to be high grade and normal.

24 mucosal erosions, with lichenoid features on histologic analysis were a distinct finding seen with an

25 Samples for histologic analysis were obtained from selected cores.

26 raphy, caliper measurements, flow cytometry, histologic analysis, and immunohistochemical analysis.

27 ested for strength testing, microCT imaging, histologic analysis, and multifrequency scanning probe m

28 At histologic analysis, the small islands of increased atte

29 SD OCT, then processing for high-resolution histologic analysis.

30 as measured by micro-computed tomography and histologic analysis.

31 sifications were compared with findings from histologic analysis.

32 with the degree of fibrofatty replacement at histologic analysis.

33 omputed tomography (micro-CT) assessment and histologic analysis.

34 ty of LA fibrofatty myocardial remodeling at histologic analysis.

35 Histologic and behavioral outcomes were measured in 202

36 neous disease with considerable variation in histologic and biological features.

37 tained the Dnajb1-Prkaca gene fusion and had histologic and cytologic features of human FL-HCCs: larg

38 ween males and females in a murine model via histologic and expression analyses.

39 nvasive HCC characterization on the imaging, histologic and genomics levels.

40 re imaged radiographically and processed for histologic and histobacteriologic analyses.

41 Histologic and histochemical features of FGN overlap wit

42 ovine) in breast lesions with correlation to histologic and immunohistochemical characteristics.

43 n appropriate diagnostic term when clinical, histologic and laboratory findings do not allow for spec

44 Histologic and mechanical measurements were made in C57B

45 roscopic, intraductal papillary lesions with histologic and molecular features of human IPMNs.

46 of triple-negative disease, focusing on the histologic and molecular features of the low-grade lesio

47 Only limited data exist describing the histologic and noncardiomyocyte function of human myocar

48 our analysis was inability to cross-tabulate histologic and serologic findings.

49 ucosal injury, latiglutenase did not improve histologic and symptom scores when compared with placebo

50 All groups had significant improvements in histologic and symptom scores.

51 yte populations by using flow cytometry, and histologic and ultrastructural analysis of patient tissu

52 ficity of DOTA-alendronate and elucidate the histologic and ultrastructural characteristics of the mi

53 tities with marked genetic, transcriptional, histologic, and clinical differences, with neoplasms in

54 s in mice with growth patterns and biologic, histologic, and genetic features similar to human HB tum

55 e provided new insights into the pathologic, histologic, and genomic characterization of specific tum

56 cells were characterized in flow cytometric, histologic, and immunohistochemical analyses as well as

57 After adjusting for clinical, histologic, and immunologic characteristics and treatmen

58 as well as acral nevi (n = 24) for clinical, histologic, and molecular features.

59 n inflammation was evaluated at morphologic, histologic, and molecular levels.

60 hanical testing (unconfined compression) and histologic assessment (Mankin score) served as the refer

61 Histologic assessment demonstrated neointimal hyperplasi

62 ate spatial learning and memory, followed by histologic assessment of amyloid burden and biochemical

63 lines, including additional semiquantitative histologic assessment of intrarenal polyomavirus replica

64 d the temporal pattern of the development of histologic atherosclerosis, inflammation with (18)F-FDG,

65 lts were retrospectively evaluated against a histologic, bacteriologic, and clinical standard.

66 of other glomerular diseases, and no unique histologic biomarkers for diagnosing FGN have been ident

67 mic studies have been reported for the major histologic brain tumor entities diagnosed in children, i

68 n evolution of different stages, 4 terms and histologic candidates were proposed: complete RPE and ou

69 rum creatinine level, albuminuria, and renal histologic changes (mesangial expansion, tubular injury,

70 yed protective phenotypes in joint swelling, histologic changes in inflammation, and cytokine product

71 function and nephrosclerosis-age-associated histologic changes in the kidneys.

72 ssociated with time-dependent mechanical and histologic changes of the healing tendon in a transected

73 Histologic changes, including Herovici collagen staining

74 classification of definitive PVN that groups histologic changes, reflects clinical presentation, and

75 nosis and after treatment for clinical data, histologic characteristics (allograft biopsy specimen),

76 luding body mass index, comorbidities, tumor histologic characteristics and grade, RENAL nephrometry

77 s using multimodal imaging and to review the histologic characteristics of cuticular drusen.

78 oss-sectional study designed to evaluate the histologic characteristics of graft injury in the presen

79 or and should be investigated to improve the histologic classification of pediatric ACTs.

80 Regardless of histologic classification, outcomes with deceased donor

81 islet transplant model, which enables direct histologic comparison of early engraftment immunobiology

82 Histologic comparison of the pretreatment and posttreatm

83 Laboratory imaging and histologic comparison, and retrospective, observational

84 Histologic confirmation of thymopoiesis was seen in 7 of

85 the LN compared with that in the blood pool; histologic confirmation was not available.

86 Histologic correlates for SD OCT signatures in DPED, est

87 We sought histologic correlates for spectral-domain (SD) optical c

88 ion, or epithelial injury, despite the close histologic correlation of each with CKD.

89 Treatment was well tolerated, and 100% histologic cure was achieved in 9 of 9 assessable animal

90 Further studies are needed to focus on histologic data around periapical microbiota to establis

91 ht into how SRH can deliver rapid diagnostic histologic data that could inform the surgical managemen

92 Topological data analysis of clinical and histologic data was performed to derive clusters, and th

93 es: Epidemiologic, genetic, dermoscopic, and histologic data were evaluated according to an RCM morph

94 within the past year, were missing baseline histologic data, or had no intestinal metaplasia.

95 s as well as in tuberculous lesions from our histologic database.

96 bpn1+/A17 mice, Pabpn1+/Delta mice have mild histologic defects, shorter poly(A) tails, and evidence

97 ; however, volume did not correlate with the histologic degree of LA fibrofatty replacement (r = -0.3

98 , and virtually complete follow-up; however, histologic details were missing for a proportion of exci

99 mmation in the esophagus for which a precise histologic diagnosis cannot be established.

100 and Onclarity results for HPV detection and histologic diagnosis of controls (less than cervical int

101 y and has good clinical accuracy compared to histologic diagnosis, with less cross-reactivity with un

102 senchymal malignancies exhibiting remarkable histologic diversity.

103 We evaluated the behavior-related and histologic effects of P4 and the expression of tumor nec

104 Blinded semiquantitative histologic evaluation of renal biopsies showed better pr

105 Histologic evaluation revealed that VACV infection and r

106 d-enhanced MR imaging ex vivo and subsequent histologic evaluation.

107 nternal control specimens, with clinical and histologic evaluations performed as part of a multicente

108 of the authors, this study offers the first histologic evidence demonstrating no significant differe

109 the subjects with CRC (10%) had tumors with histologic evidence for mismatch repair deficiency.

110 eveloped airway hyper-responsiveness and had histologic evidence of airway inflammation (asthma).

111 response to detection of kidney dysfunction, histologic evidence of allograft damage, or infection.

112 ration and less albuminuria, as well as less histologic evidence of glomerular injury and kidney fibr

113 Histologic evidence of intestinal disease was observed i

114 patients with symptomatic celiac disease and histologic evidence of significant duodenal mucosal inju

115 sis of celiac disease based on serologic and histologic evidence requires patients to be on gluten-co

116 cted to express oxytocin receptors, based on histologic evidence, and including core regions of the b

117 s are asymptomatic and PNI is often found on histologic examination (incidental PNI [IPNI]).

118 ea was similar with cardiac CEST imaging and histologic examination (R(2) = 0.89).

119 Histologic examination and wound culture from initial pr

120 Histologic examination confirmed complete liquefaction o

121 Histologic examination was performed at the conclusion o

122 ss sections obtained with CT angiography and histologic examination were matched.

123 Findings from histologic examination were used as the standard of refe

124 tation signal were measured with MR imaging, histologic examination, and cavitation receivers, respec

125 tissue was evaluated with vital staining and histologic examination.

126 y micro-computed tomography and confirmed by histologic examination.

127 as seen on SD OCT correlated to RPE cells on histologic examination.

128 ighted MR imaging and percentage necrosis at histologic examination.

129 ructures, warranting meticulous clinical and histologic examinations for this subset of patients.

130 this possibility by demonstrating consistent histologic expression of SSTR1, 2a, 4, and 5 in VHL-HBs.

131 Renal histologic expression of the podocyte-specific protein,

132 with a positive surgical margin) or T3 (with histologic extension beyond the prostatic capsule), no n

133 Discarding donated kidneys on the basis of histologic factors may be inappropriate and merits furth

134 Histologic features (steatosis, inflammation, and fibros

135 ical cohort of DPED eyes, and comparisons of histologic features between neovascular PED and DPED res

136 Histologic features include hyperplastic bone consisting

137 Changes in these histologic features indicate lung disease.

138 udy of small samples of complex tissues with histologic features of approximately 400 mum or more, in

139 ium which allows for real-time prediction of histologic features of colorectal polyps.

140 We studied the clinical, radiologic, and histologic features of HIV-related ischemic stroke to ga

141 nterstitial active inflammation are the main histologic features of renal allograft biopsy specimens.

142 tion of three BOT samples presenting unusual histologic features that could be associated with the de

143 Histologic features were centrally scored according to B

144 rrelations between liver shear stiffness and histologic features were higher at high frequencies than

145 Histologic features were nonspecific.

146 Other histologic features were similar between the samples stu

147 gression analysis to assess the weighting of histologic features with the diagnosis.

148 transition status, carcinoma in situ scores, histologic features, and survival.

149 fferent entities based on clinical behavior, histologic features, and/or by biological properties.

150 d (2) related the plasma BA profile to liver histologic features, disease activity, and fibrosis.

151 Tumor size, histologic features, nuclear and cytoplasmic BAP1 immuno

152 on their high penetrance, short latency, and histologic fidelity, these models of papillary and clear

153 unt by comparing in vivo results and ex vivo histologic findings and (b) assess reader variability.

154 assessed at diagnostic US with biopsy-proven histologic findings and BI-RADS 3 masses stable at 12 mo

155 ormed during esophagogastroduodenoscopy, but histologic findings at hematoxylin-eosin staining were n

156 based on demographic data and endoscopic and histologic findings at the time of index endoscopy.

157 There was also no significant difference in histologic findings between the 2 experimental groups (

158 Histologic findings confirmed cell rejection in C57BL/6J

159 men; 4 women; mean [SD] age, 33 [15] years), histologic findings confirmed standardization of interve

160 Histologic findings demonstrated objective thickening of

161 tible demographic, clinical, endoscopic, and histologic findings establish the diagnosis.

162 t was calculated to determine agreement with histologic findings for each B-mode US, sonoelastographi

163 Histologic findings from the polyps were also collected

164 We characterized the prognostic value of histologic findings in DKD for time to ESRD in native ki

165 = .22), histologic scores (relative risk for histologic findings in patients who consumed oats, 0.24;

166 Positive rates and histologic findings of initial and repeat screening were

167 Our findings suggest that histologic findings on postreperfusion biopsy associate

168 Endoscopic and histologic findings were evaluated with a validated grad

169 estimated diameter, >/=1 cm; or with villous histologic findings, high-grade dysplasia, or cancer) du

170 g outcomes, we evaluated the significance of histologic findings, read by experienced renal pathologi

171 early, precisely, and in high agreement with histologic findings.

172 nificant difference in the presence of other histologic findings.

173 es of bias and linearity relative to ex vivo histologic findings.

174 size, location, and morphologic appearance; histologic findings; and presence or absence of contrast

175 ation and fibrosis of lungs were assessed by histologic, flow cytometric, and quantitative PCR analys

176 ring, a data-driven statistical approach, on histologic, genetic, and clinical data and data regardin

177 LPAR inhibition also reduced histologic glomerular injury; decreased the expression o

178 ere compared with prognostic factors such as histologic grade (G1, G2, or G3, for low-grade [well dif

179 On multivariable analysis, histologic grade (hazard ratio [HR], 1.98; 95% CI, 1.56-

180 (urea AUC) that correlated with TRAMP tumor histologic grade.

181 rative on MRI exhibited stage I infiltrative histologic growth patterns; of the remaining 6 that were

182 Eosinophilic infiltration has long been a histologic hallmark of bullous pemphigoid (BP), a subepi

183 astoma is a pediatric tumor characterized by histologic heterogeneity, and accounts for 15% of child

184 investigators to manage large collections of histologic images and integrate them with clinical and g

185 aging technique that provides intraoperative histologic images of fresh, unprocessed surgical specime

186 41 min) after injection were correlated with histologic, imaging, and clinical findings.

187 ntestinal barrier integrity were assessed by histologic, immunohistochemical, quantitative reverse tr

188 iximab demonstrated significant clinical and histologic improvement 3 d after the initiation of thera

189 imulator, P7C3-A20, prevented behavioral and histologic indicators of peripheral neuropathy, stimulat

190 thritis models clinical (joint swelling) and histologic indices of inflammatory activity were signifi

191 rns of metastatic UM corresponded to stage I histologic infiltrative growth in the sinusoidal spaces,

192 growth patterns corresponded to stage II/III histologic infiltrative growth that replaced the hepatic

193 hout affecting clinical disease activity and histologic inflammation in 2 models of fibrosis.

194 osis, preserved renal function and decreased histologic injury, oxidative stress, and tubular cell de

195 igher proteinuria but did not correlate with histologic lesions as defined in the Banff classificatio

196 ative PCR, and PCV3 antigen was localized in histologic lesions typical of PDNS in sows by immunohist

197 extent of tissue damage, independent of the histologic lesions, and a risk predictor of kidney allog

198 cribed immune metagene expression values and histologic lymphocyte counts to quantify immune infiltra

199 tubular cell ER stress preceded clinical or histologic manifestations of the corresponding disease.

200 n biopsied mild or moderate DN with positive histologic margins that were clinically observed vs reex

201 ession was tightly associated with increased histologic markers of angiogenesis.

202 tween fluorescently labeled C2Am binding and histologic markers of cell death, including cleaved casp

203 Based on analyses of molecular and histologic markers, we found SPEM developed even in the

204 After the final scans, histologic measures of amyloid-beta (4G8), microglia (io

205 We then developed a quantitative histologic method using SRH images based on rapid image

206 Brains were processed by using standard histologic methods for visualization and examined by flu

207 luating TMJ pathology in mice using standard histologic methods is time consuming, labor intensive, a

208 mbined with close clinical, immunologic, and histologic monitoring.

209 Renal function and histologic morphology were evaluated.

210 e growth that replaced the hepatic lobule or histologic nodular growth in the portal triad that effac

211 ing measurements for hundreds of millions of histologic objects.

212 t and scalable in datasets containing 10(8)+ histologic objects.

213 Histologic observations coupled with ameloblast marker a

214 tissue that surrounded the tumors showed no histologic or biochemical evidence of injury.

215 s or negative shortly before and without any histologic or clinical signs of tumor recurrence.

216 with newly diagnosed breast cancer by using histologic or imaging follow-up as the standard of refer

217 that bortezomib prevents GFR loss, improves histologic or molecular disease features, or reduces DSA

218 Dichotomized histologic outcomes were evaluated using centrally read

219 Owing to their rarity and histologic overlap, accurate diagnosis of sarcomas can b

220 This proposed histologic parameter is an independent and unfavorable p

221 relations between tumor DWI and quantitative histologic parameters (nuclear, cytoplasmic, cellular, s

222 improvement in symptomatic, endoscopic, and histologic parameters using validated outcome instrument

223 alpha did not correlate with histologic parameters, whereas kurtosis showed significa

224 etween relative changes and biomechanical or histologic parameters.

225 The clinical and histologic phenotype, as well as the transcriptome, of i

226 arcinogenesis and risk factor differences by histologic phenotypes and developmental pathways.

227 ed thapsigargin, and by combining metabolic, histologic, physiologic, pharmacologic, thermographic, a

228 In PBC, DR represents a relevant histologic prognostic marker.

229 In patients with EoE, endoscopic or histologic remission can be identified with only modest

230 baseline, and proportion of patients with a histologic response (</=6 eosinophils/high-power field)

231 Of the 23 sarcomas, four (17.4%) showed good histologic response (three of four with >95% granulation

232 is, during therapy, and after therapy with a histologic response and event-free survival in pediatric

233 ne to week 10 were metabolic predictors of a histologic response in OS.

234 in DSQ score was -14.3 vs -7.5 (P = .0096), histologic response rates were 39% vs 3% (P < .0001), an

235 odifying postoperative chemotherapy based on histologic response.

236 0 wk (P = 0.021) were highly predictive of a histologic response.

237 ortant traditional features were age and HRL histologic results (eg, atypical ductal hyperplasia).

238 significant improvement in correlation with histologic results compared with the use of B-mode US al

239 y (US) and compression sonoelastography with histologic results in common flexor tendons of the elbow

240 Intraclass correlation with histologic results was 0.57 for B-mode US, 0.68 for sono

241 Histologic results were grade 1, normal, with parallel f

242 Intraoperative localization and histologic results were the reference standard for calcu

243 Traditional features such as age and HRL histologic results were used in the model, as were text

244 and 41 subjects (43 masses) due to high-risk histologic results.

245 weeks, which were correlated with subsequent histologic results.

246 ats, -0.22; 95% CI, -0.56 to 0.13; P = .22), histologic scores (relative risk for histologic findings

247 Histologic scores of inflammation and site-specific deve

248 apillary erythrocyte congestion and improved histologic scores of tubular injury 4 days after IRI.

249 RE, TE, and liver biopsy analysis (using the histologic scoring system for NAFLD from the Nonalcoholi

250 alue of clinical, biochemical, and all three histologic scoring systems on predicting composite endpo

251 Histologic scoring systems specific for primary sclerosi

252 Histologic scoring was performed using the Nakanuma, Ish

253 A representative histologic section from the central macula of a normal e

254 cular image compared with vessels as seen in histologic section.

255 Whole-slide imaging of histologic sections captures tissue microenvironments an

256 Four serial histologic sections from 90 archival non-small cell lung

257 Histologic sections were used for the morphometric analy

258 d RAM-11 (macrophage) expression on adjacent histologic sections.

259 rocess is ongoing integration of advances in histologic, serologic, and molecular diagnostic techniqu

260 abetes (l50 years) without DN and those with histologic signs of DN.

261 On the microstructural level, the histologic signs of nephrosclerosis (arteriosclerosis/ar

262 Finger skin necrosis and histologic signs of severe chronic allograft vasculopath

263 ges of hematoxylin-eosin-stained whole-mount histologic slices.

264 Gross examination of histologic specimens helped confirm Evans blue (bound to

265 The histologic spectrum of nonalcoholic fatty liver disease

266 Histologic steatosis grade was scored in consensus by a

267 eflective bands observed in the OCT with the histologic structures using human retinal sections and i

268 In biochemical and histologic studies of plasma, liver, muscle, and adipose

269 Initially, histologic studies that link visual field sensitivity to

270 nnecting layers are consistent with previous histologic studies.

271 ess likely to have the superficial spreading histologic subtype (P = 0.01), occurred in older patient

272 ve BRAF mutations or a superficial spreading histologic subtype (P = 0.05) compared with volar acral

273 s not associated with tumor grade (P= 0.98), histologic subtype (P= 0.17), or clinical stage (P= 0.09

274 M) represents the most common and aggressive histologic subtype among malignant astrocytoma and is as

275 susceptibility genes; statistical effect of histologic subtype, age, dysplastic nevi syndrome, and a

276 viewed with regard to age at diagnosis, sex, histologic subtype, and other tumors presented by these

277 increase the likelihood of relapse including histologic subtype, MYC rearrangement, protein expressio

278 The main predictor of outcome was the histologic subtype: EMZL, FL, and MF had a significantly

279 ger OS with eribulin was observed in all LPS histologic subtypes and in all geographic regions evalua

280 er investigated the association according to histologic subtypes and subsites in a large population-b

281 TrkA expression was independent of histologic subtypes but associated with lymph node metas

282 rences in associations between androgens and histologic subtypes of EOC.

283 Studies that included data on multiple histologic subtypes of lymphoma or non-MALT lymphomas (9

284 including regional variation, between NSCLC histologic subtypes.

285 rare tumors composed of several well defined histologic subtypes.

286 e survival (PFS), overall survival (OS), and histologic transformation according to treatment strateg

287 Excluding patients with histologic transformation at diagnosis, the 5-year cumul

288 Histologic transformation occurred in 5 patients (6.0%)

289 reated with ibrutinib has been attributed to histologic transformation or acquired mutations in BTK a

290 iagnosis, the 5-year cumulative incidence of histologic transformation was 2% (95% CI, 87% to 100%).

291 The relationship to histologic tumor extent needs to be further analyzed.

292 papillary thyroid cancer was the most common histologic type (64625 cases), and 2371 deaths from thyr

293 larization selected the clinical parameters: histologic type and clinical T stage, the (18)F-FDG PET-

294 dence and incidence-based mortality rates by histologic type and SEER stage for cases diagnosed durin

295 sk of reoperation is associated with DCIS or histologic type of the IBC.

296 B6 and B12 associations were apparent in all histologic types except adenocarcinoma, which is the typ

297 or CD24 in the nucleus in cells from various histologic types of cancer.

298 These two statistically determined histologic variables formed the basis for the definition

299 ogistic regression, revealed two independent histologic variables to be most significantly associated

300 Subependymomas, a distinct histologic variant, can also be found within the suprate