ライフサイエンスコーパス: intrathecally

1 cacy than AAV2, 5, 6, 8, and 9 when injected intrathecally.

2 t AM630, administered either systemically or intrathecally.

3 s (MM-ODNs) for PKCepsilon were administered intrathecally.

4 esia was blocked by minocycline and SB203580 intrathecally.

5 nociception was eliminated by CTAP injected intrathecally.

6 ord were stained by sodium selenite injected intrathecally.

7 ant presence of anti-B. burgdorferi antibody intrathecally.

8 of 0.027 microg in the rat when administered intrathecally.

9 ACEA-1021 intraperitoneally (1-60 mg/kg), or intrathecally (1-40 micrograms/mouse), and tested for an

10 ine, BNI) opioid receptors were administered intrathecally 10 min before each of two EA treatments at

11 (ODN) to the cloned rat KOR was administered intrathecally (12.5 microg, twice daily for 4 d) to spec

12 es to determine the relative contribution of intrathecally activated and peripheral LGI1-specific B c

13 Intrathecally administered 8d significantly reduced pain

14 he effect of intrathecally administered [D-Ala2,N-Me-Phe4,Gly5-ol]-en

15 press such pain, we evaluated the effects of intrathecally administered A(2A)R agonists on neuropathi

16 Antinociceptive synergy between intrathecally administered alpha(2)AR and opioid agonist

17 agents (alcohol, phenol, botulinum toxin A), intrathecally administered drugs (baclofen), and surgery

18 he cerebrospinal fluid (CSF), while allowing intrathecally administered drugs free passage out of tha

19 o effect on abrupt or sustained neurons, but intrathecally administered fedotozine inhibited the evok

20 We also show that intrathecally administered GDNF increases the amplitudes

21 ia when it was coinjected with TNFalpha, but intrathecally administered SB- 366791 attenuated bilater

22 Intrathecally administered U50488H had no effect on abru

23 rified NgR(310)ecto-Fc protein was delivered intrathecally after midthoracic dorsal over-hemisection.

24 ive to spinal GABA levels, GABA was injected intrathecally after nerve injury and sensory behaviors w

25 when compounds 1 and 5a,b were administered intrathecally, all produced analgesia in the tail-flick

26 w describes recent insights into the fate of intrathecally and epidurally administered opioids.

27 horylation in spinal microglia when injected intrathecally and in the BV-2 microglial cell line when

28 ecruited from the blood, have been activated intrathecally and leave the CNS after performing effecto

29 d U50488H were administered intravenously or intrathecally, and antagonists were used.

30 cluster also blocked the analgesic effect of intrathecally applied bovine adrenal medulla peptide 8-2

31 ntify underlying E2 signaling mechanisms, we intrathecally applied BSA-conjugated E2 over the spinal

32 anisms regulating analgesic effectiveness of intrathecally applied EM2 also pertain to endogenous EM2

33 strates that AQP4-specific Ig is synthesized intrathecally at disease onset and directly contributes

34 altered only modestly by morphine delivered intrathecally at spinal cord segment S1-S2.

35 All drugs were administered intrathecally at the L(6)-S(1) segmental level of spinal

36 Treatment was initiated intrathecally at the time of injury or 3 days after inju

37 modified stereotaxic frame and then injected intrathecally, at the level of the cisterna magna, with

38 when chelerythrine chloride was administered intrathecally before CAP injection.

39 ptor antagonist (NBQX, 20 nmol) was injected intrathecally before low-pH injections.

40 8 microg kg(-1), 12 microl) was administered intrathecally (C4) to anaesthetized, vagotomized and ven

41 An intrathecally delivered antisense oligonucleotide that a

42 Intrathecally delivered chondroitinase ABC (C'ase) impro

43 arabine administered either intravenously or intrathecally does not improve the prognosis of HIV-infe

44 bitors of PKCbetaII, PKCdelta, and PKC given intrathecally dose-dependently attenuated paclitaxel-ind

45 This intrathecally evoked release of spinal PGE(2) was dimini

46 uction in the DRG, whereas administering BH4 intrathecally exacerbated pain.

47 ntagonist, at doses of 0.001 and 0.003 nmol, intrathecally (i.t.) blocked the hyperalgesia induced by

48 oc-D-fluoromethylketone (BDFMK) administered intrathecally (i.t.) in a reversible spinal cord ischemi

49 When administered intrathecally (i.t.) to the lumbar spinal cord, GSK18925

50 Administration of A-134974 intrathecally (i.t.) was more potent (ED(50)=10 nmol) in

51 iven into the rostral-ventral medulla (RVM), intrathecally (i.th.) or simultaneously into both the RV

52 directly to the spinal cord (10 or 25 microg intrathecally [i.t.] in 5 microl saline) induced pupilla

53 During studies in which drugs were delivered intrathecally in a volume sufficiently large to distribu

54 ma (horseradish peroxidase) was administered intrathecally in cats, which were then subjected to mode

55 nal cord, we have synthesized and evaluated (intrathecally in mice) a series of bivalent ligands (KDN

56 the SP(1-7) antagonist, D-SP(1-7), injected intrathecally in mice, on two nociceptive assays that ar

57 is that neuroactive metabolites are produced intrathecally in neuropsychiatric lupus erythematosus.

58 B receptor antagonist CGP 35348 was injected intrathecally in rats pretreated 24 min earlier with 1 o

59 ors (emetine or cycloheximide) were injected intrathecally in the cervical spinal cord of anesthetize

60 pb triggered potent scratching when injected intrathecally in wild-type and Nppb(-/-) mice, showing t

61 Rats intrathecally infused with IL-6 developed progressive we

62 Intrathecally-infused antibodies exhibited size-dependen

63 tihyperalgesic action, which was mimicked by intrathecally injected AM 404.

64 HSV carrying PDGF siRNA was established and intrathecally injected into the cavum subarachnoidale of

65 al hyperalgesia (von Frey fibres) induced by intrathecally injected NMDA in mice were inhibited by th

66 the importance of PIP(2) in nociception, we intrathecally injected PIP(2) into mice.

67 t-Marie-Tooth Disease (CMT1X), was delivered intrathecally into adult Gjb1-null mice, a genetically a

68 ivered chronically via fibroblasts implanted intrathecally into neonatal rats, can facilitate synapti

69 with more advanced disease were transplanted intrathecally (IT).

70 Liposomal cytarabine 50 mg was given intrathecally on days 2 and 15 of hyper-CVAD and day 10

71 ttenuated hypersensitivity when administered intrathecally or into the hindpaw.

72 show that proteasome inhibitors administered intrathecally or subcutaneously prevented the developmen

73 that administration of the neurotrophin NT-3 intrathecally or to the proximal stump can prevent axoto

74 are known to alter nociception when injected intrathecally or when released in response to capsaicin.

75 tients compared with 60% of patients treated intrathecally (P = .3).

76 esis inhibitor Cycloheximide (CXM) or saline intrathecally prior to, or immediately after, nonconting

77 However, C5a applied intrathecally produces a dose-dependent, slow-onset cold

78 plantation of lentivirus-loaded biomaterials intrathecally provides the opportunity to induce the exp

79 imals, 7-NI (1-100 micrograms), administered intrathecally, strongly inhibited the NMDA receptor medi

80 Increased amounts of intrathecally synthesized IgG and oligoclonal bands have

81 For example, the intrathecally synthesized oligoclonal bands (OGBs) in di

82 For example, the intrathecally synthesized oligoclonal bands in diseases

83 (intracerebroventricularly) or spinal cord (intrathecally) than when given systemically (intravenous

84 provide evidence that the drugs administered intrathecally to either enlargement do not spread to the

85 ur hypothesis by administering HUP-A i.p. or intrathecally to female Sprague-Dawley rats (200-235 g b

86 oligodeoxynucleotide (ODN) was administered intrathecally to L5 spinal nerve injured rats to reduce

87 When injected intrathecally to mice, CGRP8-37-cholestanol inhibited no

88 gliosarcoma cells, 125IUdR was administered intrathecally to rats as: (a) a single injection (500 mi

89 We delivered recombinant sialidase intrathecally to rats following a spinal cord contusive

90 ha 2C-adrenergic receptors were administered intrathecally to reduce the expression of these receptor

91 f adrenal medullary tissue were transplanted intrathecally to relieve intractable cancer pain, patien

92 tor terminals, but also when it is presented intrathecally to the central terminals in the spinal cor

93 Neutralizing IL-10 antibodies administered intrathecally transiently abolished the effect of ATL313

94 This study provides evidence that intrathecally transplanted NPCs interfere with the CNS-r

95 ole (a positive GT activity regulator) given intrathecally twice a day for postoperative days 1-4.

96 a GR antisense oligonucleotide administered intrathecally twice daily for postoperative days 1-6.

97 y of icilin applied topically to the paws or intrathecally was tested in rats after spinal nerve liga

98 n that any opioid administered epidurally or intrathecally will produce analgesia by a selective spin

99 zin-5-ylamino]ethyl)ph enol)] coadministered intrathecally with ATL313 abolished the action of ATL313

100 paw were measured in rats that were injected intrathecally with either an NMDA (MK-801) or an NK-1 (L

101 Animals were injected intrathecally with either Na(v)1.8 antisense or mismatch

102 DRG) of rhesus macaques that were inoculated intrathecally with live B. burgdorferi and either treate

103 ntisense oligodeoxynucleotide coadministered intrathecally with morphine prevented the upregulation o