ライフサイエンスコーパス: like a

1 hysically to infinite-range (a = 0), Coulomb-like (a = 1), monopole-dipole (a = 2) and dipole-dipole

2 We find that ultrathin ZnO behaves like a 2D semiconductor, in which charge carriers electr

3 PDI is a-b-b'-x-a', wherein the thioredoxin-like a and a' domains mediate disulfide bond shuffling a

4 in the identical genomic regions of GhMYB25-like A and GhMYB25-like D, which were encoded by cotton

5 C (PKC) together with a modified bryostatin-like A- and B-ring region, were synthesized and evaluate

6 The cochlea behaves like a bank of band-pass filters, segregating informatio

7 -doped CaZnOS is a single-domain ferromagnet like a bar magnet, and find the probable cause for the f

8 ce of a localized electronic state that acts like a barrier for exciton diffusion across the grain bo

9 al bond can be protonated and thus functions like a base.

10 The subependymal zone--like a beating heart--continuously sends new cells to di

11 alphabeta-Tubulin behaves like a bent spring, resisting straightening until forced

12 10 might serve as a structural subunit, much like a beta subunit of heteromeric nAChRs, providing onl

13 tuent into a direct activator that functions like a BH3-only protein.

14 en model quorum sensing in a dense community like a biofilm, which reveals a novel benefit to quorum

15 how these pressures shaped a bird that flies like a bird into one that flies like a fly.

16 h as the support vector machine often appear like a black box not only because the procedures are com

17 CR accommodated frequent mutations by acting like a blanket over the hypervariable epitope, thereby p

18 hydrophobic pocket, into which Met51 fastens like a bolt, and a groove of basic residues on either si

19 The chimera behaved like a bona fide Kir channel displaying an absolute requ

20 alanine residue (A6) in the atypical Walker-like A box of AaTadZ was converted to lysine, the mutant

21 ition 6 (K6) present in the canonical Walker-like A box.

22 TadZ proteins are predicted to have a Walker-like A box.

23 gems.org/gems/fselector and can be installed like a breeze via the command gem install fselector.

24 eraction within the wild type, where it acts like a bridge between two neighboring basic residues.

25 er-layer water of the hydration shell behave like a bulk and relaxes in hundreds of femtoseconds.

26 as receptors, in which alpha-latrotoxin acts like a Ca(2+) ionophore, and (2) a Ca(2+)-independent me

27 e demonstrate that recombinant CML37 behaves like a Ca(2+) sensor in vitro and, in Arabidopsis, AtCML

28 Like a canonical GluRS, GluRS1 aminoacylates tRNA(Glu1)

29 tone-DNA intermediate does not supercoil DNA like a canonical nucleosome, but has a nucleosome-like a

30 bservations argue that Mlh1-Mlh3 may not act like a canonical, RuvC-like Holliday junction resolvase

31 toma tigrinum showed that the ribbon behaves like a capacitor, charging with vesicles in light and di

32 have a detectable influence on outcome, much like a care bundle strategy.

33 nein's interaction with microtubules behaves like a catch bond.

34 Constructing a discrete model like a cellular automaton is a powerful method for under

35 a conspicuous microtubule organizing center like a centrosome.

36 Bi4O4Cu1.7Se2.7Cl0.3 behaves like a charge-balanced semiconductor with a narrow band

37 s only along the flow direction, propagating like a chemical wave.

38 hat the olfactory sensory epithelium can act like a chromatograph, separating odorants based on their

39 ntosa GTPase regulator-interacting protein-1 like), a ciliary gene mutated in Meckel-Gruber (MKS) and

40 ) is appealing for such purposes because it, like a class of ostensibly related paradigms such as bin

41 ly depolarizes the motorneurons, acting much like a classical neurotransmitter.

42 ction for their own comments that they would like a clear description of the method of use and dose a

43 50 bind to the C terminus of importin alpha5 like a "clip," stabilizing the closed conformation of AR

44 Thus, Lis1 operates like a "clutch" that prevents dynein's ATPase domain fro

45 xperiments with laccases and other catalysts like a Co(salen) type catalyst and PdCl(2) clearly demon

46 embly, the external scaffolding protein acts like a coat protein, self-associating into large aberran

47 downwardly extendible, conceptual framework--like a compass and map--for describing and exploring in

48 have identified a protein complex that acts like a compass needle to guide magnetic orientation in a

49 brain cells signal heading direction, rather like a compass.

50 r1+2xMn2O7 (x = 0.38) can essentially behave like a complete half metal.

51 CHD behaves like a complex genetic trait in most instances.

52 Thus, geminin acts both like a component of the FGF4 signal transduction pathway

53 e constant, allowing the film to behave more like a continuum material and be visually unobservable.

54 ll, this mechanosensory system is structured like a control system characterized by mechanochemical f

55 Like a conventional computer, it can use its memory to r

56 Hrt1 functions like a conventional RING E3, with its N terminus recruit

57 ost genes with surrounding genetic elements, like a convergently overlapped gene and associated trans

58 meridional overturning circulation operates like a conveyor belt, transporting cold waters equatorwa

59 interactions, the cytoplasmic space is more like a crowded party in a house full of furniture than a

60 ogy of the as-formed Si-GR composites looked like a crumpled paper ball and the average size of the c

61 embers of the Arabidopsis cellulose synthase-like A (CSLA) family have previously been shown to synth

62 rated that members of the cellulose synthase-like A (CslA) family of glycosyltransferases from Arabid

63 encoded by members of the cellulose synthase-like A (CSLA) gene family.

64 hological transformation in which they fold, like a cup, onto themselves and in so doing take a large

65 Thus, overall, HAO is seen to act like a cytochrome c nitrite reductase, which catalyzes t

66 NARFL (nuclear prelamin A recognition factor-like), a cytosolic protein that plays a role in the cyto

67 living cells from inanimate components seem like a daunting task.

68 form a coherent Fermi liquid but instead act like a dense array of elastic impurities, interacting in

69 h signalling and cell cycle progression acts like a developmental clock, providing a delimited window

70 from higher brain inputs activating the MLR like a dimmer switch.

71 tune' and sometimes report that music sounds like a 'din' or 'banging'.

72 its destination, suggesting that ARL-8 acts like a dispersant to prevent premature synaptic assembly

73 cific truncation events, either from GhMYB25-like A DNA site or from GhMYB25-like D DNA site, were de

74 sign principle and making the device "sniff" like a dog.

75 in that binds to the epidermal growth factor-like-A domain of the low density lipoprotein receptor (L

76 The innate immune system is like a double-edged sword: it is absolutely required for

77 -propeller with a central pore and is shaped like a doughnut.

78 submembraneous network of actomyosin, braced like a drum.

79 ustrates that the cytosolic domain is shaped like a dumbbell and that the receiver domain is flexible

80 function and suggest that INAD behaves more like a dynamic machine rather than a passive scaffold, r

81 Much like a factory, the endoplasmic reticulum (ER) assembles

82 tion rather than cooperative tasks, behaving like a facultative social parasite.

83 e-third that of the Sun was observed to look like a fading pair-instability supernova.

84 utrinos radiate to space from Earth, shining like a faint antineutrino star.

85 s the active part of configuration that acts like a far-field radiative thermal diode.

86 In a report reading like a fascinating detective story, Vincent and colleagu

87 can respond and be aligned to magnetic field like a ferromagnetic material.

88 Why doesn't the world look like a film recorded on a shaky camera?

89 y the hydrophobic carbonaceous matrix acting like a filter favoring the release into water of carboxy

90 ons projecting from the globular domain of M like a finger and thumb.

91 untwist and clamp tightly around the ligand like a finger-trap toy.

92 s, suggesting that the mechanism of Nhp6A is like a flexible hinge more than that of HMGB2(Box A).

93 The collective can sometimes flow like a fluid or jam and rigidify like a solid.

94 nerate a signal with an inverse Stokes shift like a fluorescent dye, but with a narrower emission.

95 d that flies like a bird into one that flies like a fly.

96 ticipant to believe that other people do not like a food affects food liking evaluations.

97 tion that is based on pairwise interactions, like a force field.

98 unctionalized substrates containing moieties like a free phenol, indole and pyridine.

99 consistent with that of a regulatory protein like a G-protein-coupled receptor rather than a transpor

100 xtended functionality of Asp-168, which acts like a gatekeeper by altering the width of the heme cavi

101 As a consequence, this channel acts like a "ghost" of the limit cycle destroyed in the criti

102 suggesting that the GIRK1 subunit functions like a GIRK4 subunit with Na(+) permanently bound.

103 in stabilization of cell structures, and lp5-like, a glycine rich protein putatively related to cell

104 H3 looks like a glycosyltransferase, a family of enzymes that tra

105 question its role in fibrogenesis, it seems like a good time for debate.

106 Like a growing number of rapidly developing countries, I

107 ne-adapted A/H1N1 viruses evolved from avian-like A/H1N1 ancestors in similar ways, as might be expec

108 contains two iron atoms, but does not behave like a hemerythrin.

109 Like a HFD, ex vivo treatment of intestinal organoid cul

110 nning along the back of the protein that act like a hinge during domain motion.

111 We demonstrate that HbI functions like a homodimeric mechanical device, such as pliers or

112 Like a homologous protein cloned from radish (Raphanus s

113 Finally, lactate appears to act like a hormone that modifies the expression of various p

114 human and a surrogate constructed to behave like a human.

115 However, like a hydrogen bond, the cation-pi interaction exhibits

116 cytoplasmic catalytic domain of DesK behaves like a kinase at low temperature and like a phosphatase

117 AVR1-like (A-L), a close homolog of AVR1, also acts as a viru

118 Administration of Sativex-like (a laboratory preparation comprising equal amounts

119 pendent effects, making their interplay more like a language within the chromatin signaling pathway t

120 Clostridium thermocellum (Cth) Hen1, shaped like a left hand, grabs the flexible insertion module of

121 ich is not a specific substrate for XPD but, like a lesion, inhibits CT.

122 ive site entrance, while another domain acts like a lid, opening and closing access to the hydrophobi

123 9-loop that prefers to cover the active site like a lid.

124 melanoma survival and proliferation, acting like a lineage survival oncogene.

125 embrane reservoir; then the membrane behaves like a lipid bilayer with a comparable stretching modulu

126 e find that Ag nanoparticles can be deformed like a liquid droplet but remain highly crystalline in t

127 is impacted by a sphere, its surface deforms like a liquid yet it preserves a circular crater like a

128 hose structures are topologically disordered like a liquid, but nevertheless retain short-range struc

129 symmetric sites, and using a probe that acts like a local noise.

130 e curve and hypothesize that the SCN behaves like a lock-in amplifier to entrain to the light edges o

131 This distribution behaves like a lognormal distribution around the centre, and lik

132 The N-terminal coiled-coil region works like a long-range lever to precisely direct tRNA 3' end

133 Patients who have a specific history like a long-term drug treatment or a palpable tumour sho

134 igand behaved, regardless of ligand density, like a low density, high affinity ligand in all these pa

135 iple molecular subtypes, including two basal-like, a luminal, a claudin-low, and a subtype unique to

136 the promoter, the polymerase simply behaves like a machine, quickly "reading the gene." However, ove

137 The mutated residue acts like a mechanochemical coupling element--it transmits ch

138 The proposed methodology, like a meta-analysis approach, may begin to lay a possib

139 esistivity is low (0.36-0.49 muOmegam) and - like a metal - drops linearly with decreasing temperatur

140 is a semiconductor, we show that it behaves like a metallic conductor would under photocathodic H(2)

141 us with a splash cup fruiting body appearing like a miniature bird's nest of 'eggs' or peridioles tha

142 "switch region", as well as with alpha2-heme like a molecular "sticky tape" with the last 3-4 carbon

143 ly different polarities and to self-assemble like a molecular amphiphile.

144 t that the silver cluster-DNA conjugate acts like a molecular beacon but is distinguished because the

145 DgrA) of Bacillus subtilis inhibits motility like a molecular clutch that disengages MotA.

146 dicate that a synthetic nanopore can be used like a molecular gate to discriminate between the second

147 Poleta acts like a 'molecular splint' to stabilize damaged DNA in a

148 As a result, the ebvIL-10 dimer functions like a monomer at low IL-10R1 levels, which prevents eff

149 As phi29 DNAP synthesizes DNA and functions like a motor to pull a single-stranded template through

150 noglobulin isotype of unknown function, acts like a mucosal antibody.

151 jects trained for 8 weeks on a CL game that, like a musical instrument, challenged them to monitor su

152 Like a mutant encoding truncated vhs, the RNase(-) virus

153 ert unless they are heated or held together--like a nano-contact glue.

154 nd acoustically subwavelength layer behaving like a nearly-reflectionless surface with arbitrary wave

155 ombined with global increased stiffness, act like a "needle in a ball of yarn", enhancing the ability

156 competitive inhibition by L-methionine, much like a negative feedback loop.

157 on is shown to be induced by the QES, acting like a negative internal pressure, which drives the crys

158 spikes of Cdk1 activation, to one that acts like a negative-feedback-only oscillator, with a shorter

159 and manipulate complex data structures, but, like a neural network, it can learn to do so from data.

160 hich form the esophageal hiatus are arranged like a "noose" around the esophagus.

161 e encoding MyBP-HL (myosin-binding protein-H like), a novel member of the myosin-binding protein fami

162 n contrast, the tel1-DeltaC mutation behaved like a null mutation, conferring defects in both DNA dam

163 Like a number of neuropeptides, galanin can alter neural

164 Therefore, we propose that, like a number of other human diseases, AI appears to be

165 owing a caesium atom that behaves chemically like a p-block element under these conditions.

166 hat the hummingbird tongue does not function like a pair of tiny, static tubes drawing up floral nect

167 It is useful because it behaves like a partial agonist.

168 1 in a conserved docking mode, and thus acts like a pattern recognition receptor.

169 tical for PCP-signaling - Dsh(Y473F) behaves like a PCP-specific allele; and (3) defects associated w

170 ver time, the weight of attention has swung, like a pendulum, between these 2 related foci.

171 ps of related sequences are in some respects like a periodic table for biology, allowing us to unders

172 to capture and force substrates out of cells like a peristaltic pump.

173 behaves like a kinase at low temperature and like a phosphatase at high temperature.

174 Thus, the shortest dyad basically acts like a photoacid.

175 hat the lateral helix of subunit L functions like a piston, but rather, they suggest that conformatio

176 the remarkable ability to use their nucleus like a piston, switching from low- to high-pressure prot

177 onality (that is, whether the sample is more like a point, a strand or an extended structure such as

178 nd the dynamics of ubiquitin to be even more like a polycrystalline material in which the alpha-helix

179 onsist of material deposited on the surface, like a polymer brush, or variation in a fluid's refracti

180 ApoL1 has been hypothesized to function like a pore-forming colicin and has been reported to hav

181 MTs, the cytoplasm-filled astral MTs behave like a porous medium, with its permeability decreasing w

182 etric), we found that dedifferentiation acts like a positive selective force in the stem cell populat

183 ange in balance converts a circuit that acts like a positive-plus-negative feedback oscillator, with

184 whereby individual advancement comes to seem like a possibility.

185 In cell culture, the V124W mutant behaved like a potent AEf: expression of HBV carrying the V124W

186 ognormal distribution around the centre, and like a power law distribution in the tails.

187 h a target mRNA to form a tertiary structure like a pre-tRNA and recruit intracellular ribonuclease P

188 This work, like a previous study examining TktA (12), shows that un

189 This conopeptide, like a previously characterized peptide in the same fami

190 create a multiscale comparative "map" that, like a principal-components representation, captures the

191 Critically, this positive belief behaves like a probabilistic prior, i.e. its influence reduces w

192 hibitor imatinib polarized TAMs to become M2-like, a process which involved TAM interaction with apop

193 ated but isolated from other subgraphs, much like a "processing" system.

194 ate was inactive, the diester (2cPE) behaves like a prodrug and is converted into the active species

195 imulating the neighboring MyoD gene but more like a promyogenic lncRNA that acts directly or indirect

196 rea of the opposite sliding surfaces and act like a protective film to prevent direct contact and sei

197 rred enzyme for quantification of the avenin-like A proteins, the B-, D- and gamma-hordeins, chymotry

198 icosahedral [Cu8S12]16- clusters that behave like a pseudo-octahedral unit in the bonding pattern and

199 Ebp2 thus acts like a pseudosubstrate that directly recruits Fbw7 to nu

200 Protein tyrosine phosphatase-like A (PTPLa) has been implicated in skeletal myogenesi

201 l cytoplasmic Ca(2+)-H+ exchange (cCHX) acts like a 'pump' without a membrane and may be operational

202 Like a quantum computer designed for a particular class

203 Accordingly, cells behave like a rad53 loss-of-function mutant and show reduced NH

204 Thus, like a radio, human primary auditory cortex is able to t

205 copolymer is shown to be and to behave more like a random coil homopolymer, after passing through a

206 Phosphorylation makes the CTD more like a random coil leaving open the question of how Src

207 In contrast, the GRE2 promoter operates like a rapid off/on switch in response to increasing osm

208 Few examples capture the imagination like a rapid strike from a venomous snake.

209 t the priority map combines bottom-up inputs like a rapid visual response with an array of top-down s

210 Like a rapidly expanding tumor mass, obese adipose tissu

211 t mechanism for amplification that functions like a ratchet: Sound-evoked forces, acting on the basil

212 studies have revealed that BSco behaves more like a redox protein than a metallochaperone.

213 Moreover, like a reduction of ASIC1a, the number of spine synapses

214 These results demonstrate that MeCP2 behaves like a repressor even in the absence of methylation.

215 H(2) oxidation activity; thus, O(2) behaves like a reversible inhibitor rather than an agent that ef

216 APE profile that human experts agree 'looks' like a riboSNitch.

217 -1 genome and to mRNA sequences with a HIV-1-like, A-rich nucleotide composition.

218 r, like other hexameric helicases, is shaped like a ring with two tiers, an N-tier ring composed of t

219 /organs in simple yet fundamental geometries like a ring, a sheet of tissues, and a Y-shaped, bifurca

220 Adapting to perturbations driven by a device like a robot or a treadmill leads to only partial genera

221 Most materials shrink laterally like a rubber band when stretched, so their Poisson's ra

222 l response with an array of top-down signals like a saccade plan.

223 mplicating involvement of additional factors like a scaffolding molecule.

224 ly and behaves structurally and functionally like a scaled version of the branching networks in the l

225 We find that the diode behaves like a Schottky junction and that changes in electron tr

226 does not bore its way through the mucus gel like a screw through a cork as has previously been sugge

227 distilled as well as natural water resources like a sea, lake, and river.

228 ld be discernible by modelling the transport like a semiconductor with a transport edge and a transpo

229 doped semiconductor below 50 K and acts more like a semimetal at higher temperatures.

230 Though nonhuman animals lack anything like a set of grammatical structures in their natural vo

231 artyl protease shown to be capable of acting like a sheddase, similar to members of the rhomboid fami

232 m this prediction and show that the PCM acts like a sieve.

233 opose that this live attenuated vaccine acts like a silent natural infection in priming or boosting h

234 form a reactive intermediate, which behaves like a silver-bound aryl cation or 1,2-carbene-silver ca

235 n's wavelength indicate that this structure--like a similar corrugation previously identified in the

236 ing that, if neuronal variability is Poisson-like, a simple linear combination of population activity

237 tars, often making them look from a distance like a single star.

238 ed from the circulation by renal filtration, like a small molecule, due to their high aspect ratio.

239 by traversing the plasma membrane directly, like a small-molecule prodrug.

240 rom each other has 60 vertices and is shaped like a soccer ball.

241 etimes flow like a fluid or jam and rigidify like a solid.

242 a liquid yet it preserves a circular crater like a solid.

243 nts and a non-swimming self-bending behavior like a somersault, which is quite different from the pre

244 ace can range from a targeted list of genes, like a specific pathway, all the way to an ensemble of g

245 We propose that CFA/I pili behave like a spring to maintain attachment to the gut lining d

246 gement such that the RFX5(N) dimer is shaped like a staple.

247 ree-dimensional metallosupramolecules shaped like a Star of David were synthesized by the self-assemb

248 We show how the toxin acts like a straightjacket on the ligand-binding domain (LBD)

249 eriments, the molecular-motor myosin behaves like a strain sensor, exhibiting different functional re

250 far as our eyes are concerned, light behaves like a stream of particles.

251 vide evidence that Mlh1-Mlh3 does not behave like a structure-specific endonuclease but forms polymer

252 52 of the prodomain occupies the active site like a substrate for peptide synthesis.

253 Ebp2 binds to Fbw7 like a substrate, and this is mediated by an Ebp2 degron

254 nism whereby the anchoring protein functions like a subunit of Ca(V)1.2-LQT8 channels that stabilizes

255 m genome-wide association studies might seem like a sudden development.

256 It is, therefore, acting like a surfactant capable of forming hydrogen bonds with

257 GO can act like a surfactant, as measured by its ability to adsorb

258 nipulate surface tension and, as such, acted like a surfactant.

259 Here we show that Start behaves like a switch due to systems-level feedback in the regul

260 that the Drosophila mushroom body functions like a switchboard in which neuromodulation reroutes the

261 Like a thermostat that controls both heating and cooling

262 "Evolution behaves like a tinkerer".

263 transparent during the microemulsification, like a titration.

264 hat, according to linear elasticity, behaves like a topological mechanical insulator whose zero-energ

265 hodopsin can bind its agonist in equilibrium like a traditional GPCR, provide evidence that an active

266 Multiple helicase molecules can align like a train on the DNA track.

267 Our results show the motor system can behave like a trajectory controller but only if a "desired traj

268 dence that the human motor system can behave like a trajectory controller, and return the limb to its

269 ormational duality that enables it to behave like a transmission switch, with helix disruption decrea

270 rocess or a particular stimulus of interest, like a treatment or virus infection.

271 Within neuroengineering, BMI is like a tree that opens its branches into many traditiona

272 We arrived at a module which binds the knob like a trimeric clamp.

273 This TLS not only acts like a tRNA to drive aminoacylation of the viral genomic

274 we postulate that normal ABL1 kinase behaves like a tumor suppressor and therapeutic target in leukem

275 Our data suggest that ICMT behaves like a tumor suppressor in PDA because it is required fo

276 sophila tumor necrosis factor (TNF), behaves like a tumor suppressor that eliminates oncogenic cells

277 t TCF-4 is Wnt-promoting, whereas TCF-1 acts like a tumor suppressor.

278 Our results suggest that Dnmt3a may act like a tumor-suppressor gene in lung tumor progression a

279 The protein complex functions like a turbine; the proton flow drives the rotation of t

280 Our results show that MYPT1(1-98) behaves like a two-domain protein in solution.

281 MD2 binds the nucleoside-binding pocket like a two-pronged plug inserting into a socket.

282 an interesting model because of its very RNA-like A-type duplex conformation and because activated 3'

283 omplex of its prodomain and catalytic domain like a typical protein convertase, but it does not devel

284 motor skill, such as a tennis stroke, feels like a unitary experience, researchers who study motor c

285 ature is the axon initial segment which acts like a valve to tightly regulate the flux of molecules b

286 that a high risk vascularized cornea behaves like a vascularized solid organ transplant.

287 is located between two lobes and which acts like a Venus flytrap.

288 outinely used techniques to study hydration, like a very simple spectrum, single point calibration, a

289 understanding of why memory does not operate like a video recording.

290 esearch showing that memory does not operate like a video recording.

291 In this distinct state, tantalum flows like a viscous fluid while retaining its crystal lattice

292 nterface demonstrated that the biofilm flows like a viscous liquid under high flow velocities applied

293 on in which UL50 clamps onto helices of UL53 like a vise.

294 aneously in a tissue region, NO can act more like a volume transmitter to influence, and perhaps coor

295 ance occurs and the tri-layer structure acts like a wide-angle antireflection coating achieved by des

296 osaic, in the absence of activator, performs like a wild-type AGPase that is partially activated with

297 est possible algorithm identifies an object (like a word) in noise, its threshold is independent of h

298 Thus, an object, just like a word, can play the role of a symbol that stands f

299 and back and forth, in a manner that appears like a "worship".

300 mum spacing can interlock with multiple TLR9 like a zipper, leading to multivalent electrostatic inte