ライフサイエンスコーパス: long-term

1 reproductive endocrine system that persisted long-term.

2 d human tumour explants were allowed to grow long-term (14-35 days) and phenotypic features of perfus

3 To evaluate the long-term (24-month) efficacy and safety of ranibizumab

4 To determine whether a long-term (3-yr) maintenance program after PR preserves

5 -scale biosand filters (BSFs) and assess the long-term (9 month) efficacy for particulate and Escheri

6 Long-term AAS use appears to be associated with myocardi

7 major public health threat, including in the long-term acute care hospital (LTACH) setting.

8 In a multisite cohort of long-term acute respiratory distress syndrome survivors,

9 CSK9 inhibitors may impede access and reduce long-term adherence.

10 ts short in vivo half-life is an obstacle to long-term administration.

11 enology than above-average temperatures, the long-term advance in phenology was reduced.

12 n and behavioral tests showed no significant long-term adverse effects on sciatic nerve functions.

13 gnancy complication which has short-term and long-term adverse health ramifications for both women an

14 atment cancer care, including monitoring for long-term and late effects, and concerns regarding the e

15 D but not IAA altered the actin structure in long-term and short-term assays.

16 ory deaths in 2010 that were attributable to long-term annual O3 exposure based on the updated relati

17 nent surfaces may have an edge in creating a long-term antibacterial environment.

18 We are unable to comment on long-term antibody sensitisation effects.

19 blood of aviremic HIV-1-infected patients on long-term antiretroviral therapy, and their frequency in

20 Long-term aspirin use was not associated with cancer-spe

21 In patients with long-term aspirin use, the changes of molecular events i

22 accounting for them had little effect on the long-term association between SBP and mitral regurgitati

23 , this is the first study to investigate the long-term association of antioxidant supplement use and

24 in a neuronal mRNA pool during an olfactory long-term associative memory (LTAM) in Caenorhabditis el

25 We investigated the effects of long-term average climate [i.e. 35-year mean annual clim

26 ether 1 semen sample could represent a man's long-term average values in epidemiologic studies.

27 ntral nervous system (CNS) inflammation with long-term behavioral and cognitive alterations.

28 ble pulsing behavior, allowing us to perform long-term behavioral tracking.

29 this requires additional information on the long-term benefits (e.g., life-years gained and mortalit

30 tanding of the interactions, both short- and long-term, between CS and SS firing.

31 In long-term bioluminescence recordings, GABAA receptor blo

32 n how net and gross carbon fluxes affect the long-term carbon isotope mass balance, and may lead to r

33 eta-blockers, dual antiplatelet therapy, and long-term cardiovascular events.

34 cile incidence and risk factors in acute and long-term care.

35 59 Dutch nursing home wards for long-term care.

36 change to the CS-US time interval results in long-term changes in cortico-striatal synaptic efficacy

37 duced by PAR1 activation leads to short- and long-term changes in excitatory synaptic transmission.

38 but exhibited normal responses to subsequent long-term chitooctaose treatment, such as gene expressio

39 d Rhadinovirus protein that is necessary for long-term chronic infection by these viruses.

40 e result of adaptive changes acquired during long-term circulation of avian-origin IAVs in mammals.IM

41 lonized water reservoirs may be required for long-term clearance.

42 ng will have normal coronary arteries and no long-term clinical events.

43 We evaluated long-term clinical features, longitudinal immunoreconsti

44 resence of obesity have potential short- and long-term clinical implications.

45 Further study is needed to assess safety and long-term clinical outcome.

46 ently restructured to ensure that short- and long-term clinical outcomes continue to improve.

47 somatosensory cortex somatotopy can predict long-term clinical outcomes for carpal tunnel syndrome.

48 Further research is needed on procedural and long-term clinical outcomes.

49 Our study underscores the need for long-term clinical trials in adolescents with at least 5

50 extensive neural damage, often resulting in long-term cognitive impairments.

51 carcinoma is an exceptional and poorly known long-term complication after pancreaticoduodenectomy.

52 r therapy is associated with both short- and long-term complications.

53 Living with a long-term condition such as sickle cell disease during a

54 Research on the long-term consequences emphasises that, for many patient

55 ly-life stress is known to alter health, its long-term consequences on mortality remain largely unkno

56 The analyses used long-term, continuous electrocorticography from nine sub

57 short in duration, and usually detected with long-term, continuous monitoring.

58 weeks (WCWs) have been used to assess asthma long-term control but have never been validated for AD.

59 roviral roll-out programs remain a threat to long-term control of the HIV-AIDS epidemic in low- and m

60 elogenous leukemia (CML) may be relevant for long-term control or cure of CML.

61 hyroidism could improve outcomes and produce long-term cost savings.

62 al antibody responses, involved in providing long-term cross-protection against H3N2 influenza virus

63 Our data demonstrates that extensive long-term culture-induced MSC aging impaired their osteo

64 The primary outcome was a composite of long-term CV events or death, which was assessed via nat

65 on, excellent rate performance, and superior long-term cycling stability over 200 cycles at a high cu

66 tative genetic framework to individual-based long-term data for a wild rodent population and show tha

67 Analysis of long-term data revealed abrupt and synchronous changes i

68 ver time at half (50%) of the locations with long-term data, the vast majority of which (74%) were in

69 cings, such as tectonics, sea-level fall and long-term decline in greenhouse gas concentrations durin

70 d, elevated CO2 and temperature will lead to long-term declines in the amount of carbon stored in agr

71 of growth dependent on the assumed extent of long-term decoupling.

72 ement (PROM) tools is recommended to capture long-term degree of health outcomes.

73 learn with very little data, and (c) bridge long-term dependencies between actions and rewards.

74 role for this pathway in activity-dependent long-term depression (LTD) at hippocampal Schaffer colla

75 requency stimulation-induced NMDAR-dependent long-term depression (LTD).

76 previous reports implicating SRF and MEF2 in long-term depression (required for Dc-ODP), and CREB in

77 ion of cerebellar output mediated in-part by long-term depression of parallel fiber-Purkinje cell syn

78 y in neurons in response to the induction of long-term depression.

79 mpal neurons abolishes NMDA-induced chemical long-term depression.

80 Owing to a long-term development of reducing the sizes of devices,

81 s can be tackled in the short term, and what long-term directions are envisioned.

82 than 800,000 people annually, while creating long-term disability in millions more.

83 to current TK inhibitors, and in most cases, long-term disease-free survival may only be achievable w

84 Former smokers with long-term e-cigarette-only or NRT-only use may obtain ro

85 These long-term effects are usually ascribed to low fitness co

86 aphic cycle of trees, efforts to predict the long-term effects of a changing climate on tropical fore

87 persons with previous TB disease may reflect long-term effects of antibiotic TB treatment on the micr

88 However, the long-term effects of liraglutide on renal outcomes in pa

89 to ecological processes that demonstrate the long-term effects of soil contamination.

90 bsence of clear evidence in support of their long-term efficacy is leading many patients who could be

91 f daily drug treatment may be sufficient for long-term efficacy.

92 ldlife, livestock and humans world-wide, but long-term empirical datasets describing this condition a

93 (>34-mmol) difference in sodium intake with long-term estimations.

94 Long term evaluation of the electrode was found to be st

95 scalar, such as fitness, that would describe long-term evolutionary outcomes.

96 erein primary human healthy liver cells form long-term expanding organoids that retain liver tissue f

97 d old pools will likely differ and alter the long-term fate of soil C, but these separate pools, whic

98 Also, long-term follow-up of patients with TTP is crucial to i

99 Conclusion With an 83% 8-year OS rate, long-term follow-up of the FOLL05 trial confirms the fav

100 remained significantly increased, even after long-term follow-up of up to 20 years.

101 emic safety signals were observed during the long-term follow-up period.

102 We used data from the Gulf Long-term Follow-up Study, a cohort of workers and volun

103 Long-term follow-up was included in the third protocol a

104 A minority of patients developed cysts at long-term follow-up, 1 of whom had permanent neurologica

105 tion, stroke, or repeat revascularization at long-term follow-up.

106 cal prognostic factors related to IBTR using long-term follow-up.

107 y of wind power, suggesting that advances in long-term forecasting could be exploited to markedly imp

108 tential to improve the therapeutic ratio and long-term function for these patients.

109 than 95% in many centres but improvement of long-term function remains a challenge.

110 the expression of gene programs required for long-term functional and structural plasticity changes.

111 on regulates HSC fate and how it affects the long-term functionality of HSCs and the blood system as

112 emissions from waste treatment plants, (iv) long-term gaseous and liquid emissions from landfills, (

113 logistical requirements and implications for long-term graft patency.

114 e printed black phosphorus is stable against long-term (> 30 days) oxidation.

115 es, incidence of hepatic encephalopathy, and long-term (>3 months) need for paracentesis after TIPS p

116 teract with genetic risk to produce negative long-term health consequences such as neurodegenerative

117 ity and morbidity rate and adversely affects long-term health outcomes.

118 ldren is associated with poor short-term and long-term health outcomes; however, the frequency of AKI

119 tus (SES) can have negative consequences for long-term health.

120 t al. report the unexpected observation that long-term high salt intake did not increase water consum

121 th-care goals has great potential to improve long-term HIV treatment outcomes.

122 cell-intrinsic manner to mount an effective long-term humoral immune response following immunization

123 ously established Drosophila heart model for long-term hypoxia exposure, we found that hypoxia caused

124 regulating the lifespan of Drosophila during long-term hypoxia.

125 significant structural changes in boutons in long-term imaging experiments.

126 ffer from low potency, inability to generate long-term immune memory and decreased activities against

127 s and to diagnose and identify correlates of long-term immunity.

128 ificant chronic kidney disease and requiring long-term immunosuppressive treatment.

129 ssive lytic gene expression but did not have long term impact on monocyte identity regarding their di

130 Nevertheless, studies that document their long-term impact are scarce.

131 t common congenital infection that can cause long-term impairment (LTI).

132 x of awake adult mice and is associated with long-term improvement of tone-discrimination abilities.

133 ck of non-specific sensor fouling may enable long-term in situ sensor array operation in low resource

134 Long-term increased lithium exposure in drinking water m

135 onsidered to be an inevitable consequence of long-term inflammation in patients who did not respond t

136 We also summarize our long-term institutional experience, in which postshunt b

137 , pDCs upregulate neuropilin-1 to enable the long term interactions of pDCs with Treg cells, thereby

138 outcomes of irrigated systems at large, this long-term irrigated study provides valuable empirical ev

139 ects of TRPV1-mediated hypothermia by DHC on long-term ischemic stroke injury and functional outcome.

140 We tested the bone status of long-term KTR using all 3 techniques.

141 ted with culture, genome sequences of eleven long-term laboratory-adapted parasite strains were exami

142 We evaluated the responses of AM fungi in a long-term leaf litter addition and removal experiment in

143 (+) T cells) from donor mice with HF induced long-term left ventricular dysfunction, fibrosis, and hy

144 nducible expression of OCT4 (iOCT4) supports long-term LIF-independent self-renewal of ES cells cultu

145 ia) and proposes that resources continue for long-term maintenance in resource-poor countries of AFP

146 ating prescription opioid dependence, and is long-term maintenance of opioid agonist treatment associ

147 The role of marginal populations for the long-term maintenance of species' genetic diversity and

148 h induced by UV light exposure that requires long-term management because a small proportion of the d

149 cularly because these patients often require long-term medical care.

150 Vector-induced short- and long-term Mef2c upregulation in mouse prefrontal project

151 ced memory reactivation during sleep renders long-term memories of negative experiences more negative

152 gy switch in the mushroom body that controls long-term memory encoding.

153 mission of food preference (STFP), mice form long-term memory of food odors presented by a social par

154 hought to be a critical mechanism supporting long-term memory stabilization.

155 ck into working memory during retrieval from long-term memory.

156 schema congruence has a strong influence on long-term memory.

157 ring remains important for the prevention of long-term microvascular complications in adults with typ

158 In the current study, we used long-term mobile sleep monitoring and functional neuroim

159 e-STI testing services require long-term monitoring and evaluation.

160 erals it does not provide a simple proxy for long-term monitoring of biodegradation of hydrocarbons i

161 been suggested to be a biological marker of long-term morbidity and mortality; however, few studies

162 ensory-predominant with pain and can lead to long-term morbidity in survivors.

163 ut surgical outcomes and impact on short and long-term morbidity rates are yet to be determined.

164 erative complications, short-term morbidity, long-term morbidity, short-term mortality, and long-term

165 The long-term mortality among patients with undiagnosed diab

166 We found an increased long-term mortality in individuals with wet AMD treated

167 Long-term mortality in the propensity score-matched popu

168 g, is associated with substantial short- and long-term mortality.

169 ng-term morbidity, short-term mortality, and long-term mortality.

170 chronic dialysis, hospital readmission, and long-term mortality.

171 We studied the modularity in long-term motor memories in the context of locomotor ada

172 Our model allowed the long-term multisite recording from pure axonal branches

173 lpine areas, it is crucial to identify their long-term natural trends, ecological thresholds, and res

174 A long-term net CO2 uptake of >200 g CO2 m(-2) yr(-1) is r

175 Childhood CSE is associated with substantial long-term neurological morbidity, but primarily in those

176 ocus, including firefly luciferase, to allow long-term, non-invasive imaging of Hmox1 expression, and

177 Prevalence of long-term opioid therapy among patients with polyneuropa

178 d functional status among patients receiving long-term opioid therapy.

179 ients with polyneuropathy who were receiving long-term opioids had multiple functional status markers

180 Few long-term or controlled studies of bariatric surgery hav

181 aim of the present study was to analyze very long-term outcome after MV repair and replacement for de

182 We assess long-term outcome and prognosis factors for vascular com

183 were extended with additional treatment and long-term outcome data.

184 Infected children with a better long-term outcome had higher numbers of B cells at birth

185 s and quantifies PR and CR as surrogates for long-term outcome in MGN.

186 hese noncardiac complications may affect the long-term outcome in these patients and what modifiable

187 nical value of this marker as a predictor of long-term outcome merit further evaluation.

188 sed or treated at our institution to analyze long-term outcome, response to treatment, and incidence

189 graft loss, and a major barrier to improving long-term outcomes after intestinal transplantation.

190 ion and its association with in-hospital and long-term outcomes among patients with decompensated HFp

191 The results suggest that good long-term outcomes can be achieved using aflibercept for

192 at 6-month outcomes may be useful to predict long-term outcomes in CAF procedures with or without add

193 Therefore, we investigated the negative long-term outcomes of cancer-bereaved sons' and daughter

194 To compare the safety and long-term outcomes of MAG vs LITA+SVG among overall and

195 5766 participants in a prospective study of long-term outcomes of pediatric patients with IBD (NCT00

196 This meta-analysis aimed to compare the long-term outcomes with both devices.

197 ffolds have the potential to further improve long-term outcomes, they have not yet achieved results e

198 lar obstruction present at baseline on these long-term outcomes.

199 vide complementary prognostic information on long-term outcomes.

200 of previous COPD admissions, previous use of long-term oxygen, age, and BMI.

201 determine whether cell sheets generated with long-term passaged (P10) aging human mesenchymal stromal

202 We discuss causes and functions of short and long-term patterns of specialization for bumblebee colon

203 d trafficking of CAR T cells to and impaired long-term persistence at the tumor site, as well as the

204 volution and translational regulation to the long-term persistence of generalist parasitism.

205 To prevent photo-toxicity and to allow for long-term photo-stimulation without causing cellular dam

206 fiber-Purkinje cell synapse and induction of long-term plasticity (LTP) in M1, leading to transient o

207 We examined the long-term population dynamics of the invasive common was

208 Our results suggest that long-term population size and cost of complexity drive t

209 tment option, but its success depends on the long-term potential for reduced chromium precipitates to

210 rs in the environment and landfills can be a long-term, (potentially) substantial source of PFOS.

211 tly reduced and the resulting suppression of long term potentiation (LTP) by Abeta oligomers was prev

212 odic memory, and synaptic changes induced by long-term potentiation (LTP) are thought to underlie mem

213 ors (betaARs) enhances both the induction of long-term potentiation (LTP) in hippocampal CA1 pyramida

214 hannels completely suppressed development of long-term potentiation (LTP) in the CA1-subiculum, but n

215 Long-term potentiation (LTP) in the rat hippocampus is t

216 models demonstrated exaggerated hippocampal long-term potentiation (LTP), consistent with deficits i

217 ngth by facilitating an anti-Hebbian form of long-term potentiation (LTP).

218 epression (required for Dc-ODP), and CREB in long-term potentiation (required for Pc-ODP).SIGNIFICANC

219 Synaptic plasticity (e.g., long-term potentiation [LTP]) is considered the cellular

220 and concomitantly rescues their hippocampal long-term potentiation deficit.

221 ted mGlu5 receptor-dependent facilitation of long-term potentiation in the IL-PFC.

222 showed reduced initiation and maintenance of long-term potentiation of glutamatergic synapses.

223 lteration of synaptic strength necessary for long-term potentiation, learning, and memory.

224 avage, ameliorates synapse loss and augments long-term potentiation, resulting in protection of memor

225 Best Practice Advice 9: Long-term PPI users should not routinely screen or monit

226 sh oil might have prophylactic potential for long-term prevention of asthma in offspring.

227 To compare improvement in long-term prognostication of incident CHD and ASCVD usin

228 break and related microcephaly clusters as a long-term program of work.

229 d B (PiB) positron emission tomography after long-term prospective follow-up.

230 earch on vaccine approaches that can provide long-term protection against dengue virus infection is n

231 Thus, failure to establish long-term protective Ab titers against S. aureus was not

232 n human sarcomas was evaluated by short- and long-term rapamycin treatment in sarcoma cell lines.

233 phically separated, multifocal tumors and/or long-term recurrent tumors are seeded from different clo

234 received sacubitril/valsartan had a greater long-term reduction in HbA1c than those receiving enalap

235 matic changes, in which sky-islands acted as long-term refuges and cradles of genetic diversity.

236 With the extreme sensitivity of AMS, the long-term release and retention of the actinides was inv

237 capacity, biocompatibility, scalability, and long-term reliability.

238 pment of innovative treatment strategies for long-term repair and regeneration of injured or diseased

239 scular disease, we examined the influence of long-term residential transportation noise exposure and

240 term can be either positive or negative, but long term responses will be negative for all populations

241 fferential epigenetic marking may facilitate long-term retention of duplicate genes.

242 nt of microalbuminuria and macroalbuminuria, long-term risk factors for renal and cardiovascular dise

243 lipid homeostasis, but its relevance to the long-term risk of developing metabolic disorders is unkn

244 We evaluated the long-term risk of SMNs in a well-characterized cohort of

245 ing studies have investigated short- but not long-term risk.

246 his study will provide more insight into the long-term safety and efficacy of bariatric embolization.

247 No new or long-term safety concerns were identified.

248 ollow-up studies are needed to establish the long-term safety of these strategies.

249 ostly than MR cholangiopancreatography, with long-term savings of $1870 and $2068 versus noncontrast

250 ed by short-term solar UV irradiation, and a long-term skin carcinogenesis study showed that deletion

251 anges of transient species expanded over the long-term, slowly increasing their regional retention an

252 However, long-term sports participation may be associated with ad

253 e CA2/CA3a is crucial for the persistence of long-term SRM.SIGNIFICANCE STATEMENT Oxytocin receptors

254 Long-term SSRI treatment may delay progression from MCI

255 The remarkable analytical parameters and long term stability of both the sensors could be envisio

256 chemical properties, in-vivo performance and long term stability under electrical stimulation of a ne

257 ectivity among multi-competitive components, long-term stability during the detection of NA may open

258 s with high energy and high power densities, long-term stability, safety and low cost.

259 Further, the sensor exhibited long-term stability, which could be due to the strong me

260 devices to operate with high efficiency and long-term stability.

261 lls in tolerant recipients may contribute to long-term stable graft acceptance.

262 effects on regeneration dynamics play out in long-term stand dynamics.

263 All of the reagents are stable during long-term storage and can be prepared in advance.

264 r, there are environmental concerns with the long-term storage and implications of a leak from a carb

265 Additional studies of long-term surgeon trainer proficiency, community-specifi

266 ica, yet few facilities are able to maintain long-term surveillance.

267 In the current era, with long-term survival after systemic treatment, there is a

268 confers an energetic disadvantage to PCs for long-term survival and antibody production.

269 n of transcriptional mechanisms that support long-term survival and differentiation of repair cells w

270 the transcriptional mechanisms that control long-term survival and phenotype of repair cells have no

271 peat revascularization and an improvement in long-term survival and should be considered more frequen

272 Long-term survival data are lacking, and prognostic fact

273 is steadily increasing, but the knowledge on long-term survival in this group is scarce.

274 re-resection for both patient selection and long-term survival is not known.

275 erica, is caused by Borrelia burgdorferi The long-term survival of B. burgdorferi spirochetes in the

276 of a caspase-independent cell death and the long-term survival of FA-treated cells.

277 iated with lower operative mortality, better long-term survival, and fewer valve-related complication

278 ansplantation may offer their best chance at long-term survival.

279 abnormalities that are associated with poor long-term survival.

280 tying and bile reflux are common concerns in long-term survivors after Whipple surgery.

281 l therapies were enumerated and described in long-term survivors.

282 raised interest in accessing the quality of long-term survivorship.

283 granule cell activity.SIGNIFICANCE STATEMENT Long-term synaptic plasticity is a fundamental property

284 d how appropriate spike patterns could drive long-term synaptic plasticity remained unknown.

285 amine receptor (D1R) expression, and ensures long-term synaptic plasticity.

286 ation of photosynthetic rates constrains the long-term temperature dependence of GPP, and highlights

287 of these symbiotic associations and, in the long term, their usefulness in agricultural settings.

288 of therapy, and patient participation in the long-term therapeutic strategy.

289 aft acceptance without significant short- or long-term toxicity.

290 Still, to date the long-term trajectories of social impairment in psychotic

291 These results indicate that long term transgene expression consistency and T-DNA ins

292 s can predict 2-month culture conversion and long-term treatment outcome.

293 (grade 0, 1, or 2) demonstrated a favorable long-term treatment response in 87% of patients (complet

294 Continuation of omalizumab after long-term treatment results in continued benefit, as evi

295 it is unclear if this net decline reflects a long-term trend.

296 Long-term trends in excess risk of death and cardiovascu

297 SCD is mostly reliant upon opioids; however, long-term use of opioids is associated with multiple sid

298 o functional status markers were improved by long-term use of opioids.

299 ing fetal exposure to drugs and xenobiotics, long-term use of these medications may affect fetal drug

300 Long-term variations in the earthquake recurrence interv