ライフサイエンスコーパス: metallo

1 The use of Turbo Grignard generated the metallo-2-pyridyl intermediate more reliably than alkyll

2 artic, ~19% (44/233) cysteine, ~40% (93/233) metallo, ~28.3% (66/233) serine and ~6.4% (15/233) threo

3 , ~8% (12/150) are cysteine, ~58.7% (88/150) metallo, 30% (45/150) serine and ~3.3% (5/150) are threo

4 cribes the fabrication of electropolymerized Metallo 4', 4'', 4''', 4'''' tetra-amine phthalocyanine

5 to add further insight into the chemistry of metallo-Abeta, which may assist better understanding of

6 itors, including aspartic (HIV protease) and metallo (ACE and thermolysin) proteases.

7 The metallo-activated complexes of all of these compounds we

8 lyze two genetically essential P. falciparum metallo-aminopeptidases (MAPs), PfA-M1 and Pf-LAP.

9 M1 family metallo-aminopeptidases fulfill a wide range of critical

10 a parasite Plasmodium falciparum employs two metallo-aminopeptidases, PfA-M1 and PfA-M17, which are e

11 es may reflect an evolutionary adaptation of metallo and nonmetallo KDO8PS's to the cellular concentr

12 Both APs were sensitive to both metallo and sulfhydryl type inhibitors.

13 nclude homologs of beta-1,3-glucanases (16), metallo- and aspartyl proteases (13), glycerophosphodies

14 ctronic similarities and differences between metallo- and organic OPEs can be understood largely on t

15 Key similarities between the metallo- and organic OPEs that bear on materials-related

16 dothelial cells in the presence of the major metallo- and serine protease systems that modified peric

17 ry cells through connective tissues involves metallo- and serine types of cell surface proteases.

18 Examples of serine, cysteine, aspartic, metallo- and threonine proteinases linked to animal prog

19 chemistry related areas: molecular switches, metallo-assemblies and sensors.

20 urther solution studies demonstrate that the metallo-base pair is compatible with Z- or B-DNA conform

21 crystal structure of a duplex containing the metallo-base pair.

22 nally high kinetic stabilities of T-Hg(II)-T metallo-base pairs (half-lives = 0.3-1.3 h) perturbed dy

23 wo tandem cGMP-binding sites downstream of a metallo beta-lactamase domain, a superfamily that includ

24 Metallo beta-lactamase enzymes confer antibiotic resista

25 yme active site provides a binding model for metallo beta-lactamase inhibition with utility for futur

26 hibit L2 (serine beta-lactamase) but not L1 (metallo beta-lactamase) from the extensively drug resist

27 Metallo beta-lactamases (MbetaL) are enzymes naturally e

28 It appears that the metallo beta-lactamases bind their substrates by establi

29 tly discovered inhibitors of serine and some metallo beta-lactamases.

30 ored K. pneumoniae carbapenemase (56.1%), 54 metallo-beta-lactamase (40.9%), and four both (3.0%).

31 umoniae carbapenemase (blaKPC) and New Delhi metallo-beta-lactamase (blaNDM) genes.

32 IMP-1 metallo-beta-lactamase (class B) is a plasmid-borne zinc

33 The Etest metallo-beta-lactamase (Etest MBL) strips consisted of a

34 ch X-ray absorption spectroscopy of a dizinc metallo-beta-lactamase (MbetaL) reaction intermediate.

35 hETHE1 is a mono-iron binding member of the metallo-beta-lactamase (MBL) fold superfamily.

36 ontaining a motif related to the prokaryotic metallo-beta-lactamase (MBL) fold.

37 olate had VIM-2 and IMP-18, and 7 carried no metallo-beta-lactamase (MBL) gene.

38 Metallo-beta-lactamase (MBL) inhibitors can restore the

39 The metallo-beta-lactamase (MBL) is a candidate protein fami

40 atened by the emergence and global spread of metallo-beta-lactamase (MBL) mediated resistance, specif

41 Metallo-beta-lactamase (MBL)-producing CRE have recently

42 robacteriaceae (CRE) producing the New Delhi metallo-beta-lactamase (NDM) are rare in the United Stat

43 New Delhi metallo-beta-lactamase (NDM) represents a serious challe

44 The New Delhi metallo-beta-lactamase (NDM-1) is involved in the emergi

45 region) and the catalytic efficiency of the metallo-beta-lactamase (the motions are damped out when

46 apenemase (KPC), and Verona integron-encoded metallo-beta-lactamase (VIM) were the most common carbap

47 nically relevant MBL Verona integron-encoded metallo-beta-lactamase (VIM-2).

48 the recently described antibiotic-resistant metallo-beta-lactamase 1 Klebsiella pneumoniae.

49 Metallo-beta-lactamase activity is thought to be polyphy

50 istronic operon (blhA-orfY), which encodes a metallo-beta-lactamase and a coenzyme A-disulfide reduct

51 re, mechanism, and biochemical properties of metallo-beta-lactamase Bla2 from Bacillus anthracis, the

52 information available on early stage dizinc metallo-beta-lactamase catalysis.

53 c features of the catalytic action of dizinc metallo-beta-lactamase CcrA from Bacteroides fragilis.

54 In an effort to probe Co(II) binding to metallo-beta-lactamase CcrA, EPR, EXAFS, and (1)H NMR st

55 cturally and mechanistically very similar to metallo-beta-lactamase CcrA.

56 a-lactamases and less so against the class B metallo-beta-lactamase CcrA.

57 a-lactamases and less so against the class B metallo-beta-lactamase CcrA.

58 CPSF-73 and CPSF-100 contain two domains, a metallo-beta-lactamase domain and a novel beta-CASP (nam

59 odes a protein containing a highly conserved metallo-beta-lactamase domain, within which our swip-10

60 l library of thiols/disulfides with the BcII metallo-beta-lactamase enabled the rapid identification

61 se RNase J, a member of the widely occurring metallo-beta-lactamase enzyme family.

62 opening (AHL lactonases) are members of the metallo-beta-lactamase enzyme superfamily and rely on a

63 o beta-lactam antibiotics can be mediated by metallo-beta-lactamase enzymes (MBLs).

64 Metallo-beta-lactamase enzymes are encoded on highly tra

65 Inactivation of beta-lactam antibiotics by metallo-beta-lactamase enzymes is a well-recognized path

66 Bacteria use metallo-beta-lactamase enzymes to hydrolyse lactam rings

67 vii) delta genomes encode multiple copies of metallo-beta-lactamase enzymes; (viii) a host of secreti

68 ssay, the boronic acid synergy test, and the metallo-beta-lactamase Etest, had specificities of >90%

69 The diverse members of the metallo-beta-lactamase family are a growing clinical thr

70 at similar or identical endonucleases of the metallo-beta-lactamase family generate the 3' ends of po

71 Pso2/Snm1 is a member of the beta-CASP metallo-beta-lactamase family of proteins that include t

72 tRNase Z, a member of the metallo-beta-lactamase family, endonucleolytically remov

73 e class of these enzymes is a zinc-dependent metallo-beta-lactamase for which there are no clinically

74 ne and tryptophan side chain dynamics of the metallo-beta-lactamase from B. fragilis have been examin

75 nem- and cephamycin-resistant dinuclear zinc metallo-beta-lactamase from Bacteroides fragilis and its

76 The L1 metallo-beta-lactamase from Stenotrophomonas maltophilia

77 ve, estimating a lower bound of evidence for metallo-beta-lactamase functionality but not an upper bo

78 , given that ancestral proteins may have had metallo-beta-lactamase functionality with variation in s

79 of these models conform to our criteria for metallo-beta-lactamase functionality, suggesting that th

80 hat the integration site disrupts a putative metallo-beta-lactamase gene with a 21.3 kb deletion enco

81 , and bla(B/C) confirmed the presence of the metallo-beta-lactamase genes.

82 and metal substituted Bacillus cereus (BcII) metallo-beta-lactamase have been investigated.

83 lts give the first structural information on metallo-beta-lactamase ImiS and suggest that the second

84 dy of a spin-labeled variant of the class B2 metallo-beta-lactamase ImiS identified movement of a com

85 The metallo-beta-lactamase IMP-1 catalyzes the hydrolysis of

86 nterobacteriaceae strain harboring the NDM-1 metallo-beta-lactamase in a pediatric patient in the Uni

87 ted with the nonoutbreak spread of New Delhi metallo-beta-lactamase in diverse Enterobacteriaceae spe

88 The designed metallo-beta-lactamase is functional in the Escherichia

89 an effort to further probe metal binding to metallo-beta-lactamase L1 (mbetal L1), Cu- (Cu-L1) and N

90 Metallo-beta-lactamase L1 from Stenotrophomonas maltophi

91 effort to probe whether the metal content of metallo-beta-lactamase L1 is affected by metal ion bioav

92 residues 152-164), a site-directed mutant of metallo-beta-lactamase L1 was engineered that contained

93 he structure of the reaction intermediate of metallo-beta-lactamase L1 when reacted with nitrocefin a

94 ort to probe the role of the Zn(II) sites in metallo-beta-lactamase L1, mononuclear metal ion contain

95 s with the preparation of Co(II)-substituted metallo-beta-lactamase L1, two strategies were undertake

96 characterize the roles of each metal ion in metallo-beta-lactamase NDM-1, heterodimetallic analogues

97 In an effort to biochemically characterize metallo-beta-lactamase NDM-1, we cloned, overexpressed,

98 e an acceptable diagnostic reagent to detect metallo-beta-lactamase phenotypes in the clinical microb

99 Artemis is a member of the metallo-beta-lactamase protein family of nucleases.

100 ARTEMIS is a member of the metallo-beta-lactamase protein family.

101 e highest-resolution structural data for any metallo-beta-lactamase reported to date.

102 Metallo-beta-lactamase screening tests were positive, PC

103 This marks the first preparation of a metallo-beta-lactamase selectively substituted with a pa

104 ng Escherichia coli cells carrying New Delhi metallo-beta-lactamase subclass 1 (NDM-1) can be monitor

105 Escherichia coli cells expressing New Delhi metallo-beta-lactamase subclass 1 (NDM-1), an emerging a

106 These enzymes are members of the metallo-beta-lactamase superfamily and contain two zinc

107 ts subunit 11 (IntS11), which belongs to the metallo-beta-lactamase superfamily and is a paralog of C

108 ese AHL lactonases have been assigned to the metallo-beta-lactamase superfamily of proteins, which in

109 se of their relation to other enzymes in the metallo-beta-lactamase superfamily.

110 which are metalloproteins that belong to the metallo-beta-lactamase superfamily.

111 CphA is a Zn(2+)-dependent metallo-beta-lactamase that efficiently hydrolyzes only

112 Insidious coproduction of metallo-beta-lactamase with KPC-type carbapenemase has i

113 superfamilies, including the amidohydrolase, metallo-beta-lactamase, and enolase superfamilies.

114 effort to probe the structure of a group Bb metallo-beta-lactamase, Co(II)-substituted ImiS was prep

115 Here we report an artificial metallo-beta-lactamase, constructed via the self-assembl

116 mase domain and a novel beta-CASP (named for metallo-beta-lactamase, CPSF, Artemis, Snm1, Pso2) domai

117 to understand the reaction mechanism of a B2 metallo-beta-lactamase, steady-state and pre-steady-stat

118 M), the gene encoding the emerging New Delhi metallo-beta-lactamase, using label-free electrochemical

119 iotic resistance factor called the New Delhi metallo-beta-lactamase-1 (NDM-1) has been found to confe

120 mediated resistance, specifically New Delhi metallo-beta-lactamase-1 (NDM-1).

121 New Delhi metallo-beta-lactamase-1 was found in almost every conti

122 y drug-resistant E. coli harboring New Delhi metallo-beta-lactamase-1.

123 hat the ancestor was unlikely to have been a metallo-beta-lactamase.

124 15 coproducing an AmpC and 11 coproducing a metallo-beta-lactamase.

125 ecially with isolates coproducing an AmpC or metallo-beta-lactamase.

126 lysis by the Stenotrophomonas maltophilia L1 metallo-beta-lactamase.

127 ESBL in 90.1% of isolates that coproduced a metallo-beta-lactamase.

128 SNM1B/Apollo is a member of metallo-beta-lactamase/betaCASP family of nucleases and

129 shared sequence homology with beta-lactamase/metallo-beta-lactamases (enzymes that provide resistance

130 preparation of a set of clinically relevant metallo-beta-lactamases (i.e., NDM-1 (New Delhi MBL), IM

131 -A, and SME type), 40 isolates that produced metallo-beta-lactamases (including NDM-1, GIM-1, SPM-1,

132 Metallo-beta-lactamases (MbetaLs) are the main mechanism

133 Metallo-beta-lactamases (mbetals) confer broad-spectrum

134 ria pose a major health threat by expressing metallo-beta-lactamases (MbetaLs), enzymes able to hydro

135 (ESBL), KPC- and OXA-type carbapenemases and metallo-beta-lactamases (MBL).

136 Metallo-beta-lactamases (MBLs) are a growing threat to t

137 Although transmissible metallo-beta-lactamases (MBLs) are a serious threat to b

138 Metallo-beta-lactamases (MBLs) are particularly problema

139 Metallo-beta-lactamases (MBLs) efficiently hydrolyze and

140 Metallo-beta-lactamases (MBLs) hydrolyze almost all beta

141 Development of metallo-beta-lactamases (MBLs) inhibitors has proven cha

142 tance to beta-lactam antibiotics mediated by metallo-beta-lactamases (MBLs) is a growing problem.

143 The acquisition of metallo-beta-lactamases (MBLs) such as NDM-1 is a princi

144 reaction mechanism to be offered for the B2 metallo-beta-lactamases and demonstrate that the mono- a

145 ass of monocyclic beta-lactams are stable to metallo-beta-lactamases and have excellent P. aeruginosa

146 the determinants of substrate specificity in metallo-beta-lactamases and the design of potentially cl

147 nies of the Subclass B1 + B2 and Subclass B3 metallo-beta-lactamases and their homologs show that the

148 bacteria that produce extended-spectrum- and metallo-beta-lactamases are being discovered at an alarm

149 Metallo-beta-lactamases are native zinc enzymes that cat

150 Metallo-beta-lactamases are responsible for conferring a

151 ient formats were developed for detection of metallo-beta-lactamases based on the reduction of imipen

152 Metallo-beta-lactamases catalyze the hydrolysis of most

153 Metallo-beta-lactamases challenge antimicrobial therapie

154 The metallo-beta-lactamases constitute Class B in the Ambler

155 The Ambler Class B metallo-beta-lactamases fall into two distinct phylogene

156 t for the broad substrate specificity of the metallo-beta-lactamases from Bacteroides fragilis and ot

157 Recently however, metallo-beta-lactamases have originated in Asia.

158 cific detection of carbapenemases, including metallo-beta-lactamases in active bacterial pathogens.

159 Reduced holomycin also strongly inhibits metallo-beta-lactamases in vitro, major contributors to

160 A structural feature shared by the metallo-beta-lactamases is a flexible loop of amino acid

161 a kinetic mechanism similar to that used by metallo-beta-lactamases L1 and CcrA, in which a reactive

162 ism of hydrolysis of nitrocefin by binuclear metallo-beta-lactamases may be atypical and that cleavag

163 the binding of substrates and inhibitors to metallo-beta-lactamases may involve binding to the organ

164 Furthermore, in contrast to metallo-beta-lactamases or Klebsiella pneumoniae carbape

165 additional support to the proposal that the metallo-beta-lactamases should be divided into two disti

166 However, avibactam does not inactivate metallo-beta-lactamases such as New Delhi metallo-beta-l

167 nding site is very similar to those of other metallo-beta-lactamases that belong to the B1 subclass.

168 now report KPC serine carbapenemases and the metallo-beta-lactamases VIM, IMP, and NDM-1, even though

169 nhibitors effective against both serine- and metallo-beta-lactamases, and which could also have antim

170 we reconstructed a sample of 98 MRCAs of the metallo-beta-lactamases, each based on a different tree

171 EDTA was found to be a better inhibitor of metallo-beta-lactamases, especially for anaerobes.

172 ibiotics are recognized by dizinc-containing metallo-beta-lactamases.

173 esign of novel inhibitors of NDM-1 and other metallo-beta-lactamases.

174 -1 is similar in structure to other class B1 metallo-beta-lactamases.

175 carbapenemases, and the VIM, IMP, and NDM-1 metallo-beta-lactamases.

176 ith rate constants slower than those of most metallo-beta-lactamases.

177 the same mandate exists for the detection of metallo-beta-lactamases.

178 te metallo-beta-lactamases such as New Delhi metallo-beta-lactamases.

179 New Delhi metallo-beta-lactmase-1 (NDM-1) has recently emerged as

180 A novel metallo-bioadhesive to be used as tissue sealant in mini

181 Our work provides new evidence into the metallo-biology of PD and opens new lines of research as

182 oped into the planes of borophenes to create metallo-borophenes, opening vast opportunities to design

183 emases in Enterobacteriaceae, while OXA- and metallo- carbapenemases are of growing importance in Aci

184 bly detected isolates with KPC and most with metallo-carbapenemases.

185 The metallo carbenoid derived from the D/A diazo group is pr

186 f a large subunit that harbors a NiFe(CN)2CO metallo-center and a small subunit with three iron-sulfu

187 that acts on amyloid by perturbing amyloid's metallo-chemistry, and Clioquinol treatment has been sho

188 es (UV-vis and fluorescence spectra) of the (metallo)chlorin-like chromophores that possess slightly

189 flavodoxin essential for assembly of the RNR metallo-cofactor) have been identified and characterized

190 beta contains the metallo-cofactor, essential for the initiation of the re

191 ed to self-assemble to form a three stranded metallo-coiled coil, Ln(III)(MB1)3.

192 Here we present outcomes for the metallo-complex Cu(II)(atsm) tested for therapeutic effi

193 Here we report the novel use of a metallo-complex, desferrioxamine-gallium (DFO-Ga) that t

194 hree members of the metallocarboxypeptidase (metallo-CP) family that had not been described in the li

195 Pd3L2 metallo-cryptophane cages with cyclotriveratrylene-type

196 specific members of the protein phosphatase metallo-dependent (PPM/PP2C) family and is independent o

197 Both dihydroorotases are members of the metallo-dependent hydrolase superfamily, whose members h

198 Here we report the crystal structure of a metallo-dependent or class II FBP aldolase from an extre

199 en the individual porphyrin systems, and the metallo derivatives also displayed significant variation

200 ap resonators, and, more recently, metallic, metallo-dielectric and plasmonic resonators.

201 Compact metallo-dielectric hybrid clusters with subwavelength di

202 ve metamaterial properties of thin, periodic metallo-dielectric multilayers by exploiting a broadband

203 Further, we identified the metallo-endopeptidase CpaA, which has been shown previou

204 ibP), proposed to encode a lysostaphin-like, metallo-endopeptidase that is exported to the periplasm

205 substrate binding pocket conserved in active metallo-endopeptidases has been adapted to control PG hy

206 rally and/or biochemically characterized are metallo-endopeptidases that cleave cross-links in the pe

207 tructures resemble lysozyme-like enzymes and metallo-endopeptidases, respectively.

208 Enone hydrometalation produces metallo-enolates en route to aldol and Michael cycloredu

209 group; (2) [3+n]-cycloadditions (n = 1-5) by metallo-enolcarbenes formed by catalytic dinitrogen extr

210 +1]-cycloaddition of catalytically generated metallo-enolcarbenes was successfully extended to reacti

211 of biomimetic complexes for the modeling of metallo-enzyme active sites is a fruitful strategy for o

212 hich spin-state is key, including catalysis, metallo-enzyme modeling studies, and host-guest chemistr

213 IP5 2-K from Arabidopsis thaliana is a zinc metallo-enzyme, including two separated lobes (the N- an

214 onal and aberrant hole-transfer reactions in metallo-enzymes.

215 molecular dynamics simulations of the dizinc metallo form indicates that the dinuclear metal cluster

216 difference in DNA affinity for the different metallo forms of Fur.

217 monoxide, aldehydes, and olefins to produce metallo formyl, alpha-hydroxyalkyl, and alkyl complexes,

218 activity and regioselectivity of (endohedral metallo)fullerenes have in the past decade been shown to

219 e on interactions of diastereomerically pure metallo-helical 'flexicate' complexes, bimetallic triple

220 ates the potential of utilizing well-defined metallo-helical complexes for cancer chemotherapy.

221 lutarate, and acetate to a C(3)(v) symmetric metallo-host (1) are characterized in terms of the bindi

222 ne) complex affords the first supramolecular metallo-hydrogelator that not only self assembles in wat

223 or the first time the identification of five metallo-intramembrane cleaving proteases in Anabaena var

224 Unlike Class-I KDO8P synthases, the Class II metallo-KDO8P synthases containing Zn2+, Cd2+, Cu2+, and

225 metallo KDO8PS from Escherichia coli and the metallo KDO8PS from Aquifex aeolicus are the best charac

226 rovided by beta-lactamases belonging to both metallo (MBL)- and serine (SBL)-beta-lactamase subfamili

227 s the catalyst, tandem 1,3-acyloxy migration/metallo-Nazarov cyclization/1,6-enyne addition/Cope rear

228 ng a more rapid tandem 1,3-acyloxy migration/metallo-Nazarov cyclization/[4 + 2]-cyclization pathway

229 ement and control the emergent properties of metallo-OPE materials.

230 of an orthogonal mid-pi/pi*-gap d orbital in metallo-OPEs.

231 tions and oxygenations in the absence of any metallo- or organic cofactor.

232 Photoredox catalysts are metallo- or organo-compounds capable of absorbing visibl

233 e inhibitors (PMSF, Pefabloc SC), but not by metallo- or thiol-protease inhibitors.

234 This opens up a new field of metallo-organic antifreeze protein mimetics and provides

235 In addition, metallo-organic catalysts are inherently susceptible to

236 Unlike metallo-organic catalysts, polyoxometalate anions are ox

237 eral of my group's research contributions in metallo-organic chemistry over the past 40 years.

238 plexes were employed to construct brominated metallo-organic intermediates, followed by a Suzuki coup

239 were prepared based on the careful design of metallo-organic ligands (MOLs).

240 py-Ru(2+) -tpy was employed to construct two metallo-organic ligands for the assembly of G2 and G3 Si

241 The metallo-organic ligands L(A) and L(B) with multiple free

242 nder equilibrium control, numerous nanoscale metallo-organic particles with potentially useful proper

243 With clusters deposited via metallo-organic Pt or PtRu(5) complexes, previous experi

244 and ferrous ions, Fet3p can be considered a metallo-oxidase and appears to play an essential role in

245 n-transfer-mediated enone reduction produces metallo-oxy-pi-allyls en route to [2 + 2] cycloadducts a

246 These enzymes constitute an unusual pair of metallo-oxygenases that remain fully active after a meta

247 This method was applied to several metallo Pcs.

248 were not hydrolyzed by serine, aspartic, or metallo peptidases.

249 igestion (cysteine-, aspartic-, serine-, and metallo-peptidases), cell, protein and lipid binding inc

250 sc-PLD) is a member of the diverse family of metallo-phosphodiesterase/phosphatase enzymes that also

251 The protein consists of a core binuclear metallo-phosphoesterase fold (exemplified by bacteriopha

252 Metallo-photoredox catalysis has redefined the available

253 olecular beacon (MB) probe consisting of two metallo-phthalocyanine (Pc) fluorophores that use near-I

254 ther environments and by the eminent role of metallo-phthalocyanines in synthetic materials, the cont

255 Zr6-polyoxo-cluster and uniformly embedded (metallo)porphyrin centers endow CPM-99 with highly desir

256 series of zirconium polyphenolate-decorated-(metallo)porphyrin metal-organic frameworks (MOFs), ZrPP-

257 As highlighted by the functionality of metallo-porphyrins in biological or other environments a

258 terobimetallic organic catalysts compared to metallo-porphyrins.

259 ficiently inhibit anthrax lethal factor (LF) metallo-protease.

260 e presence of aspartic, cysteine, serine and metallo proteases.

261 ariety of serine-, cysteine-, carboxyl-, and metallo-proteases, including trypsin, chymotrypsin, peps

262 stic classes-serine, cysteine, aspartyl, and metallo-proteases-and develop a discriminatory scoring f

263 hibitors of chymotrypsin-like, cysteine-, or metallo-proteases.

264 Mutations in the metallo-protein Cu/Zn-superoxide dismutase (SOD1) cause

265 n health and disease: decorin and the Matrix Metallo-Proteinase (MMP) collagenase.

266 serine proteinase, cysteine proteinase, and metallo-proteinase families.

267 s, serine proteinases, aspartic proteinases, metallo proteinases, and aggressive proteinase mixtures,

268 decreased expression of PD-L1 and of matrix metallo-proteinases (MMPs) and CD-10 in those cells.

269 during morphogenesis, the function of matrix metallo-proteinases (MMPs) and their inhibitors, the tis

270 complex (bio)molecular structures including metallo-proteins like myoglobin.

271 In metallo-proteins, characterization of the folding pathwa

272 ytic properties of single-atom catalysts and metallo-proteins, we exploit the potential of metal-orga

273 Of the several metallo-QDO enzymes examined for nitroxygenase activity

274 The metallo-radical catalyzed indene synthesis in this paper

275 The imine acts as a simple modular metallo-reactive fluorophore.

276 The combination of light- and metallo-responsiveness in the same polymer provides the

277 milies, C56 and C64 (cysteine), M20 and M23 (metallo), S24 and S28 (serine) as revealed by a lack of

278 ixed (Section 6), desymmetrized (Section 7), metallo (Section 8), and N-heterocyclic linkers (Section

279 The classical strategy for modeling metallo-sites relies on the synthesis of metal complexes

280 New Delhi metallo-ss-lactamase (NDM) has emerged worldwide in clin

281 in catalysis, this implies that the various metallo-substituted enzymes are capable of some level of

282 report the first X-ray crystal structures of metallo-substituted HDAC8, Co(2+)-HDAC8, D101L Co(2+)-HD

283 constructed on adamantane, three discrete 3D metallo-supramolecular architectures were assembled, i.e

284 s investigated for the first time exploiting metallo-supramolecular chemistry.

285 This metallo-supramolecular functionality allowed direct visu

286 ave achieved formation of stimuli-responsive metallo-supramolecular gels.

287 The self-assembly of irregular metallo-supramolecular hexagons and parallelograms has b

288 me, this new topology has been combined with metallo-supramolecular interactions to construct novel c

289 A particular fascinating class of metallo-supramolecular molecules are hollow coordination

290 Facile construction of metallo-supramolecular poly(3-hexylthiophene) (P3HT)-blo

291 les with Zn(2+) ion to form a highly soluble metallo-supramolecular polymer 1 with M(n) approximately

292 Such metallo-supramolecular polymers potentially offer the fu

293 e report, herein, the preparation of gellike metallo-supramolecular polymers prepared from a monomer

294 The resulting metallo-supramolecular structure explored by scanning tu

295 stituting the metal-coordinating cysteine of metallo synthases with the corresponding asparagine of n

296 several fields, provide an elegant route to metallo-tetrapyrrole systems often elusive to convention

297 The first generation (G1) metallo-triangles were directly obtained by reacting a b

298 onal supramolecular architectures, so-called metallo-triangles, were assembled from terpyridine (tpy)

299 h Zn(II) or Cd(II) to obtain high-generation metallo-triangular architectures in nearly quantitative

300 hydrophobic effect, which we define as the "metallo-zipper."