ライフサイエンスコーパス: most likely

1 ugh during which fadeout of transmission was most likely.

2 However, this error minimization is most likely a by-product of the primordial code expansio

3 catalysis of periplasmic transaminations is most likely a general tool for specific biosynthetic pat

4 Although endogenous estrogen is most likely a mediator of the observed functional differ

5 haped by an extensive genome duplication or, most likely, a whole-genome duplication (WGD), which is

6 structural integrity and that they therefore most likely act through a mechanism other than HI.

7 ab35 as a novel regulator of WPB exocytosis, most likely acting through the downstream effectors ACAP

8 to proteolysis, and an extended form, which most likely allows for effective receptor binding.

9 Our observations identified those mutations most likely amenable to pharmacological rescue in the af

10 and phylogenetic distance, antagonism being most likely among closely related species.

11 Here we find that the central TAM most likely are elevated by a non-thermal, flexural cant

12 opulation of human melanopsin-ir RGCs, which most likely are involved in different functions.

13 arbon oceans on Titan probably represent the most likely areas to find extraterrestrial life.

14 served coherence of these quasi-bound states most likely arises from phase- and frequency-synchronize

15 iffer for G4 disruption and dsDNA unwinding, most likely arising from differences in the rate-limitin

16 trong diagnostic evidence that this outbreak most likely arose from unvaccinated or under-vaccinated

17 ater, its binding leads to mRNA destruction, most likely as a consequence of translational repression

18 rphology and capacity of autonomous selfing, most likely as a way to reduce the probability of inters

19 of AnkB-Paris is indispensable for function; most likely as an ER retention motif that enables anchor

20 ne in mice decreased the liver levels of RE, most likely as the result of a gradual disappearance of

21 are clinically relevant peanut allergens and most likely associated with severe allergic symptoms.

22 Diarrhoea is most likely attributable to reduced expression of absorp

23 owever, this same processing technique could most likely be applied to any low photon-number image ir

24 perdeuterated acetone is observed, which can most likely be attributed to the exchange of a methyl gr

25 aloforms through trihaloacetyl compounds can most likely be extended to other ecosystems with organic

26 1.0 or greater identified patients at risk, most likely because of elevated PA pressures.

27 HOBTB2 was more abundant than the wild-type, most likely because of impaired degradation in the prote

28 metastases < 1.0 cm were (18)F-FET-negative, most likely because of scanner resolution and partial-vo

29 hyperplasia with bladder outlet obstruction, most likely because of stromal expansion.

30 nt mutants emerged in vitro but not in vivo, most likely because resistant mutations affected bacteri

31 SQE2, alpha-onocerin production was boosted, most likely because the epoxidases produce higher amount

32 equirement for CDK6 but not CDK4 expression, most likely because, in these cells, CDK6 was predominan

33 cules (88%) were immobile, with the molecule most likely being physisorbed or trapped; the remainder

34 cording assays, we found that an RNA aptamer most likely binds to the receptor's regulatory site and

35 uced production of proinflammatory cytokines most likely by activation of the adenosine A2a receptor.

36 ariant has been evolutionarily advantageous, most likely by augmenting resistance to malaria.

37 cally inhibited elongation of Abeta fibrils, most likely by binding to the ends of growing fibrils.

38 D substitution disrupted catalytic activity, most likely by causing an electrostatic perturbation at

39 genesis of PA14 during burn wound infection, most likely by contributing to PA14 survival in the bloo

40 ates both the ImAHP and IsAHP in OT neurons, most likely by controlling Ca(2+) entry through voltage-

41 ting NBs play a role in infection processes, most likely by enabling pathogens to outcompete commensa

42 hibited CXCR4 phosphorylation and signaling, most likely by functioning as a nonspecific CXCR4 antago

43 solvent of high dielectric constants (DMF), most likely by photoinduced electron transfer.

44 rotect mice from severe influenza infection, most likely by reducing TLR4-dependent cytokine storm me

45 duced cell death in YAMC cells and organoids-most likely by sequestering and degrading cIAP1.

46 ocyte integrity under pathologic conditions, most likely by suppression of TRPC channels.

47 ceptor ciliogenesis and retinal development, most likely by trafficking cilia and outer-segment prote

48 lic acids with molecular weight (MW) 216 Da (most likely C10H16O5) and MW 214 Da (C10H14O5) was confi

49 Although added sugars most likely can be safely consumed in low amounts as par

50 redominant cell type expressing ANO1 and the most likely candidate for SW generation.

51 The most likely candidate for the mechanism seems to be the

52 i-C genome conformation data and reports the most likely candidate genes.

53 nts to enamides, allowing us to identify the most likely catalytic cycle of the reaction.

54 We conclude that the most likely catalytic mechanism begins with abstraction

55 lable genome-analysis tools, and outputs the most likely causal DNA changes.

56 The most likely causal variant identified was a novel missen

57 ns and modeling at the site suggest that the most likely cause of the decrease in MS is the transform

58 e conclude that infertility in these mice is most likely caused by a functionally impaired BTB.

59 al (product of glutathione and MG), which is most likely caused by S-nitrosylation of aldose reductas

60 The absence of the other two decorations is most likely caused by the downregulation of phoPQ and pm

61 The results showed that the H7N8 LPAI virus most likely circulated among diving ducks in the Mississ

62 We found that the H7N8 LPAI virus most likely circulated among diving ducks in the Mississ

63 To examine the most likely conformation of the Met(20) loop during the

64 ion markers in the duct luminal cells, which most likely contribute to keratotic plug formation.

65 gate the aspects of mining operations, which most likely contribute.

66 aptive immunity by depletion of CD4 Th cells most likely contributes to loss of immune control of LTB

67 boundary subdomains between petal primordia, most likely contributing to formation of congenitally fu

68 er beetles), that had an earlier gymnosperm (most likely cycad) host association, later transitioning

69 ted by tricarboxylic acid cycle metabolites (most likely depending on the amino-terminal region aroun

70 idest diversity and may indeed represent the most likely descendants of the populations responsible f

71 iastereoselective total synthesis of the two most likely diastereomeric candidates for the structure

72 hypothesis significance tests and select the most likely differentially abundant proteins with a corr

73 ly available data shows these candidate SNPs most likely do not have biochemical function; only 13% o

74 , with this process being independent of and most likely downstream of arm-cohesin dissociation.

75 eas population studies suggest the opposite, most likely due to confounding by UV exposure.

76 d in misregulation of defense-related genes, most likely due to decreased H3K9 acetylation levels at

77 ently entirely by overcoming these defences, most likely due to elevated oxidative stress resistance.

78 maining uncleared savannas of South America, most likely due to fire suppression and land fragmentati

79 an alternative in vivo reconstitution path, most likely due to greater protein oligomerization from

80 and 7q- developed myelodysplastic syndrome, most likely due to haploinsufficiency of related 7q21.2

81 potentially resulting in improved survival, most likely due to increased mitochondrial respiratory c

82 This benefit is most likely due to inhibited corrosion as a result of su

83 evidence of fine-scale genetic structuring, most likely due to limited seed dispersal, but the overa

84 lity (HR: 3.0; 95% CI: 0.7, 12.4), which was most likely due to low power.

85 nd ILC2 responses were observed in the lungs most likely due to oxidative stress caused by neonatal h

86 tal distribution and uptake of the Zn forms, most likely due to rapid dissolution of the ZnO NPs.

87 ity in women from industrialized settings is most likely due to reverse causation: Poverty reduces ag

88 The use of hamsters has declined, however, most likely due to the dearth of genetic tools available

89 e many mechanisms to aid in protein folding, most likely due to the need for most chaperones to bind

90 lt is 8-15% lower than pure sodium chloride, most likely due to the presence of hydrates.

91 The observed effect is most likely due to the release of TF-bearing EVs of diff

92 ainted meat in cold meat products, which was most likely due to the serving temperature on the one ha

93 ion) using trisodium citrate as draw solute, most likely due to the unique swelling behavior of the p

94 temporal phases of dispersal, both of which most likely emanated from the Near East.

95 howed that the ancestor of all ST8 S. aureus most likely emerged in Central Europe in the mid-19th ce

96 The most likely etiology was determined by review of the ent

97 As plants grown in sunlight would most likely experience concomitant elevations in UV-B an

98 in hatcheries has often been invoked as the most likely explanation for reduced fitness, and most st

99 Based on our analysis, the mathematically most likely explanation for the renewed growth in atmosp

100 rature-sensitive (ts) phenotype, providing a most likely explanation for the stronger attenuation obs

101 The most likely explanation for this finding is the persiste

102 The most likely explanation is that omega-3 PUFAs lack effic

103 The expert panel concluded that (a) the most likely explanation of available evidence from outbr

104 malities including microcephaly, and (b) the most likely explanation of available evidence from outbr

105 The most likely explanation of this finding is that local em

106 endothelial growth factor treatment are the most likely explanations.

107 Hence, the dependency of gbM on a CMT most likely extends to all angiosperms and possibly gymn

108 s with diabetes living in tropical countries most likely face increased risks of common and health-ca

109 bservations, we hypothesize that trastuzumab most likely fails in the treatment of brain metastases o

110 ental results indicate that NiHi defects are most likely formed and these defects do not introduce de

111 onsistent with influxes of non-local people, most likely from northern Eurasia and the Pontic Steppe.

112 This upregulation stems most likely from reduced oxytocin expression in hypothal

113 h is consistent with multiple introductions, most likely from the northern states of Brazil, and with

114 absorption by its FAD chromophore, which is most likely fully oxidized (FADox) in the dark state and

115 oritization approach revealed rs10995 as the most likely functional single-nucleotide polymorphism, a

116 We also identified the most likely functional SNPs at each locus.

117 murine LRT and we provide evidence that PlrS most likely functions via the putative cognate response

118 circulating primary HIV-1 strains, a vaccine most likely has to induce broadly neutralizing antibodie

119 istic model to assign mapping results to the most-likely IDs, (iii) comprehensive ribosomal RNA filte

120 ed global flexibility of the Val-213 variant most likely improve its local availability and reduce th

121 nd reliable signal of early flooding stress, most likely in tight interaction with the other gases.

122 nt foraminifera in carbonate production will most likely increase in future decades.

123 modeling revealed that Cd removal processes most likely increased in magnitude substantially between

124 t the lifetimes of CPA in the atmosphere are most likely independent from the aqueous-phase pH.

125 decreased during atDCS compared with stDCS, most likely indicating augmented efficiency in brain net

126 innate immune activators and that the miRNAs most likely induce cytokine production and leukocyte mig

127 n of the functions of these transcripts will most likely inform pathomechanism.

128 G121 RNA signals through TLR13; however, the most likely intracellular receptor in human subjects is

129 e is unknown, suggesting that other loci are most likely involved.

130 alent bond, the second C-H functionalization most likely involves Ru-O coordinate bond.

131 that Spanish teosinte is of admixed origin, most likely involving Zea mays ssp. mexicana as one pare

132 FL-AE crystal structure reveals Na(+) as the most likely ion present in the solved structures, and pu

133 The cause of ice expansion is uncertain, but most likely it is related to increased atmospheric tempe

134 Most likely, KIO3 caused glutenin oxidation within each

135 at the sensory photoreceptor ribbon synapses most likely lack RIM1 and predominantly express RIM2 var

136 ent toward the center of the pore region and most likely lead to disturbance of the gating mechanism.

137 mbia which suggests that the attack rate was most likely less than 50%; and 32.4% (95% CI: 2.5-94.2%)

138 a topic of discussion and interest, with the most likely levels of least resistance being the interdi

139 We find that [Formula: see text] increases (most likely linearly) with magnetic field H and saturate

140 entation, or some combination of the two and most likely made the species even more susceptible to la

141 ved tumor targeting (biodistribution) as the most likely mechanism of AR160 therapeutic superiority o

142 The most likely mechanism of inheritance was concluded to be

143 The most likely mechanisms for these reactions are charge-re

144 e parental differentially methylated regions most likely mediate the remodeling of methylation and tr

145 The binding of these elements is most likely mediated by fast-acting long-term potentiati

146 This phenotype was most likely mediated by the robust and swift upregulatio

147 tension is SKN-1 dependent, with a mechanism most likely mimicking calorie restriction.

148 eiotropic effects in the mutated library are most likely minimized because only one gene was mutated

149 dominance with incomplete penetrance is the most likely mode of inheritance.

150 ration behavior together with accurate mass, most likely molecular formula, as well as MS/MS as requi

151 imated clonality of mutations determined the most likely MSI target genes to be the aminoadipate-semi

152 s, suggesting that, while these proteins are most likely nitrate/nitrite antiporters, they can also a

153 -length peripherin-2/rds, partitioning would most likely occur at a bilayer interfacial region, poten

154 in of this highly deviant chloroplast genome most likely occurred before the emergence of the Cladoph

155 olic Naa60 anchoring to the Golgi apparatus, most likely occurring post-translationally and specifica

156 d television consumption, after sex, was the most likely of these predictors to contribute to variati

157 This growth pattern is most likely oriented by a polarity field, highlighted by

158 Micromagnetic simulations suggest that the most likely origin is an unintentional shape anisotropy.

159 V-6B in many carriers with European ancestry most likely originated from ancient integration events i

160 r M. elongata - M. cysteinexigens symbiosis, most likely over 350 million years ago and concomitant w

161 ents to interpret BCID results, identify the most likely pathogen, and then choose therapy based on t

162 Haplotyping infers the most likely phase of observed genotypes conditional on c

163 ee-dimensional particle-hole channel EEI the most likely physical source.

164 che modeling indicated that changing climate most likely played a role in the decline of the Sumatran

165 Here, cyclin C-Cdk8 phosphorylation of Med13 most likely primes the phosphodegron for destruction.

166 ficantly reduced in affected fibroblasts and most likely produces a truncated protein (p.Val351Glyfs(

167 Nurses are the most likely professional group to provide self-managemen

168 Genetic analysis revealed that CDK-8 most likely promotes I4 neurogenesis by inhibiting the C

169 n of syngas on rhodium(111), we identify the most likely reaction mechanism.

170 Based on safety and activity, the most likely recommended phase 2 dosing is 5.4 or 6.4 mg/

171 o heart failure in chronic mountain sickness most likely reduces fitness.

172 maturation pattern and extended brain growth most likely reflect Neandertal physiology and ontogeneti

173 the carbonate record after 3.1 ka therefore most likely reflect the historical variation in hydrothe

174 Most likely reflecting the current level of completeness

175 ations of PAHs increased from south to north most likely related to a combination of coal-eroding bed

176 in into the medium just after fertilization, most likely related to the blocks to polyspermy.

177 Toxicity is most likely related to the concentration in structure, w

178 substrates compared with native proteins is most likely related to the reduced accessibility of the

179 ata, our approach revealed subjects that are most likely related, but had previously passed standard

180 ( 75.1-74.4 Ma), we argue that the two forms most likely represent a single anagenetic lineage.

181 Paucigranulocytic asthma most likely represents a "benign" asthma phenotype, rela

182 Thus AMD most likely represents an endophenotype with differing u

183 Passive immunotherapy against HIV-1 will most likely require broadly neutralizing antibodies (bnA

184 diminished motor activity of this mutant is most likely responsible for impaired hearing in the shak

185 oss the proteome and identification of those most likely responsible for the functional consequences

186 onins, flavonoids, and terpenoids, which are most likely responsible for their biological activity.

187 cidence in universal test and treat clusters most likely resulted from poor linkage to care.

188 The fourth variant in the SYTANLAAF motif most likely results in reduced permeability.

189 1,236 archaeal gene families to identify the most likely root for the tree.

190 We used the most likely scenarios to explore drivers of TB incidence

191 inating from and hosted by wild animals, are most likely shaped by commensalism related to human acti

192 ween cell infection and viral production, is most likely short ( approximately 4 h), the median withi

193 lead-rich crystal termination planes are the most likely sites for electron trapping and thus nanomet

194 We suggest that the most likely source candidates are mega-ultralow-velocity

195 oupled nitrification of newly fixed N is the most likely source of nitrogen oxides supporting nitrous

196 nfections with high parasite numbers are the most likely source of resistance emergence, so effective

197 The most likely space-time clusters of malaria incidence for

198 mate Bayesian computation suggested that the most likely speciation scenario explaining this pattern

199 aptured in a well-defined active-like state, most likely stabilized by the crystal lattice.

200 Hydrogen bonding at the indole amine most likely stabilizes the radical-like state.

201 he sigma receptor lead to oxidative species (most likely superoxide) that in turn oxidize VMAT2.

202 he dominant folded structure at high salt is most likely the antiparallel stacked-X structure.

203 nds and seasonally inundated floodplains are most likely the controlling sources of atmospheric metha

204 a mixture of conformations, one of which is most likely the open-X structure which has unpaired base

205 The deep ocean is most likely the primary source of the radiocarbon-deplet

206 onditions, this methane is not a remnant but most likely the result of ongoing leakage from the reser

207 binds a quaternary polysaccharide structure, most likely the triple helix adopted by polymerized beta

208 tack, presumably by a cephalopod; these were most likely, the top predators of the Ordovician.

209 nduced shift from cognitive to habit memory, most likely through altered crosstalk between the hippoc

210 id systems within the NAc to support reward, most likely through augmenting DA release.

211 rleukin (IL)-6 (0.3-fold of control, p<0.1); most likely through enhancing glutathione peroxidase (GP

212 NS1) of WNV antagonizes IFN-beta production, most likely through suppression of retinoic acid-inducib

213 correctly allocates cells into the autopod, most likely through the control of cell-surface properti

214 is effector is localized to the LCV membrane most likely through the ER-retention motif.

215 mple clinical method to identify individuals most likely to accrue the largest benefit from continued

216 es, namely that the small molecules that are most likely to accumulate contain an amine, are amphiphi

217 ents with severe eosinophilic asthma who are most likely to achieve clinically significant reductions

218 ansmission, prioritizing those interventions most likely to achieve population-level impact.

219 Shelf life of the studied shrimp was most likely to be 8days, and there were positive linear

220 glucose exposure, as in T2D, were considered most likely to be a consequence of hyperglycemia.

221 Understanding which species and habitats are most likely to be affected is critical for adaptive mana

222 systems in prediction of the majority phase most likely to be found.

223 tion strategy to identify which findings are most likely to be genuine, and hence worthy of further s

224 otype; cells with an oxidative phenotype are most likely to be inhibited by the mandelalides.

225 nd this gene regulatory function of ADARs is most likely to be of high biological importance beyond t

226 xpertise regarding articles we believed were most likely to be of high clinical and scientific import

227 th AD with generalized distribution were the most likely to be patch tested (OR, 4.68; 95% CI, 3.50-6

228 luate which hydrolysis reaction pathways are most likely to be relevant for organic chemicals found i

229 s measure and report those outcomes that are most likely to be relevant to users of their research.

230 The 3-ring PAHs were most likely to be taken up by maize roots whereas 2- and

231 100 M. tuberculosis strains either least or most likely to be transmitted after controlling for host

232 Interventions most likely to be used if provided were similarly ranked

233 etles able to colonize live tree tissues are most likely to become invasive pests.

234 allow the therapy to be targeted to patients most likely to benefit and not experience serious advers

235 veloping methods for targeting LTFU patients most likely to benefit can make this practice more effic

236 Baseline biomarkers can identify subjects most likely to benefit from adjunctive therapy with omal

237 and ready to make behavioral changes may be most likely to benefit from behavioral counseling.

238 l improve identification of patients who are most likely to benefit from drug treatment to prevent fr

239 Our findings could help identify patients most likely to benefit from IMiDs and suggest direct Trx

240 surement of which can help identify patients most likely to benefit from inhaled corticosteroids and

241 (ICH) expansion and may mark those patients most likely to benefit from intensive blood pressure (BP

242 iomarkers that predict subgroups of patients most likely to benefit from omalizumab.

243 Future RCTs tailored for those most likely to benefit from RIPC warrants further invest

244 needed to aid with the selection of patients most likely to benefit from stress testing after PCI.

245 roposed scoring system may identify patients most likely to benefit from surgery.

246 demonstrated utility in identifying patients most likely to benefit from targeted anti-interleukin an

247 eful for identifying the individuals who are most likely to benefit from targeted neurostimulation th

248 n, further evidence on the types of patients most likely to benefit from the use of ezetimibe in addi

249 y enabling identification of patient subsets most likely to benefit from therapies predicated on mani

250 u hybridisation (FISH) can identify patients most likely to benefit from these drugs combined with ch

251 O2 pathway analysis could identify patients most likely to benefit from treating a specific defect;

252 dentify the functional traits of individuals most likely to benefit from treatment.

253 to enrich the study population with patients most likely to benefit, based on predicted patient respo

254 se programmes and to identify those patients most likely to benefit.

255 nd how to identify those patient populations most likely to benefit.

256 uberculosis control interventions for people most likely to benefit.

257 e coverage for their use in patients who are most likely to benefit.

258 iven that spouses were among the individuals most likely to complete donation.

259 alizumab to facilitate selection of patients most likely to derive the greatest clinical benefit from

260 y shared the larvae type that their mate was most likely to desire and also increased the quantity of

261 assessed for their ability to identify those most likely to develop or die from lung cancer.

262 ts with pneumonia + acute kidney injury were most likely to die or reach major adverse kidney events.

263 e used to discern which type of mechanism is most likely to drive lateral root patterning.

264 conditions based on the prey and body states most likely to end in successful capture.

265 This is most likely to ensure sustained high-level donor chimeri

266 However, to our knowledge, the patients most likely to experience a significant response to ther

267 ive of outcome and can identify the patients most likely to experience spontaneous resolution.

268 yped features of neuronal circuits are those most likely to explain the remarkable capacity of the br

269 45 of CcmH and Cys-34 of apocytochrome c are most likely to form this mixed disulfide bond, which is

270 Finally, Euro-American isolates are most likely to have a wild-type PZase and escape molecul

271 ve appointment waiting times of 2-3 days the most likely to have patients who serially miss appointme

272 Hospitalizations were most likely to include guideline-adherent antibiotics fo

273 leep, a period when these abnormalities were most likely to interfere with memory consolidation.

274 mical volatiles emitted by bacteria that are most likely to mediate bacterial or plant responses to B

275 model can identify vector control strategies most likely to minimise the spread of insecticide resist

276 Infant deaths due to external causes were most likely to occur between 2 and 7 months of age.

277 ibution patterns when the passage of ECEs is most likely to occur from 2012 to 2016 using passive aco

278 ntly change axonal conduction properties are most likely to occur over timescales of days to weeks.

279 edicts that abrupt biodiversity declines are most likely to occur when habitat availability is reduce

280 ocessing are strikingly altered by attention most likely to optimally achieve the behavioral goal.

281 n algorithm to predict the types of N-glycan most likely to predominate at all the putative N-glycosy

282 ast likely to receive a transplant, patients most likely to receive a transplant were more likely to

283 ores, especially at the intraspecific level, most likely to reduce exposure to parasitism.

284 re further assessment and which patients are most likely to require treatment of their VWD.

285 ecular subtype may help select MIBC patients most likely to respond to Her2 targeted therapy.

286 , aneuploidy may thus help identify patients most likely to respond to immunotherapy.

287 rger cohort of patients might identify those most likely to respond to this chemoimmunotherapeutic re

288 cer cells could be used to identify patients most likely to respond to treatment.

289 bers for which drug discovery efforts may be most likely to succeed.

290 Patients with arrests in public were most likely to survive if they received both bystander-i

291 hat is difficult to cross-contaminate and is most likely to survive.

292 d uses network flow algorithms to select the most likely transcripts.

293 These ranks are used to predict the most likely transformation route when more than one stru

294 s a specialized MHC class I molecule, and is most likely transported to the cell surface only when su

295 anotransduction [5], and/or proteolysis [6], most likely under the control of transcriptional program

296 amic causal modeling to demonstrate that the most likely underlying neural network consisted of a pul

297 ndeed derived from the external environment, most likely via a conversion catalyzed by one or more 17

298 tween cognitive and habitual memory systems, most likely via altered amygdala orchestration of these

299 that atypical E2Fs act as tumor suppressors, most likely via transcriptional repression of cell cycle

300 established human cell lines to FeLV-B, the most likely zoonotic variant.