ライフサイエンスコーパス: olfaction

1 -gated channels are essential for vision and olfaction.

2 he latency of initial transduction events in olfaction.

3 elemental perceptual feature of odors in rat olfaction.

4 pid gains in our understanding of Drosophila olfaction.

5 ating the independence of this behavior from olfaction.

6 velopment of fins, tail, ear, eye, brain and olfaction.

7 humans, suggesting an indispensible role in olfaction.

8 owerful model system for studying vertebrate olfaction.

9 s, the most salient sensations are taste and olfaction.

10 urons are the primary sensory organelles for olfaction.

11 the nose, plays an important role in rodent olfaction.

12 to operate on principles inspired by canine olfaction.

13 rmine if these mice have similar deficits in olfaction.

14 mination and cortical pattern recognition in olfaction.

15 knowledge regarding why the disease impacts olfaction.

16 ey play roles in higher functions other than olfaction.

17 including autonomic dysfunction and impaired olfaction.

18 in the antennae and so could be involved in olfaction.

19 d molecular mechanisms that drive rhythms in olfaction.

20 , is one of the key factors in understanding olfaction.

21 role of UBR3 in sensory pathways, including olfaction.

22 but the principle of SAT is still debated in olfaction.

23 we present the direct observation of SAT in olfaction.

24 bulb (OB) of mice mediates daily changes in olfaction.

25 ng a central mechanism for sensory gating in olfaction.

26 ral to the mouth, associated with retronasal olfaction.

27 nderutilized, yet critical, animal model for olfaction.

28 diate diverse signaling processes, including olfaction.

29 on on the highly salient sensory modality of olfaction.

30 known, limiting mechanistic understanding of olfaction.

31 orco mutations should significantly impact olfaction.

32 cesses, including, as recently demonstrated, olfaction.

33 ng lipid metabolism, leukocyte migration and olfaction.

34 n differently affect appetite parameters and olfaction.

35 mechanism and functional logic for mammalian olfaction.

36 a and genes related to diet, metabolism, and olfaction.

37 larger integrated system of ortho-retronasal olfaction.

38 tum feeding, food reward (snack points), and olfaction.

39 nd changes that are consistent with enhanced olfaction.

40 shapes principal neuron activity to regulate olfaction.

41 ment newly offered up by vision, hearing and olfaction.

42 delayed or absent puberty and dysfunctional olfaction.

43 ng 2 questions: (1) What does AR do to human olfaction?

44 Sniffing serves olfaction [13, 14], while whisking synchronized to sniff

45 al cavity carried by the inhaled air, making olfaction a sense where animals can control the frequenc

46 e or dementia with Lewy bodies had decreased olfaction, a lesser chronotropic response to tilt, and a

47 have addressed these issues with C. elegans olfaction, a simple innate behavior mediated by sexually

48 In olfaction, a single sniff is sufficient for fine odor di

49 Here we propose that, in olfaction, a small and relatively stable set comprised o

50 In olfaction, a stereotyped map is evident in the first sen

51 Effects of ambient air pollution exposure on olfaction: a review.

52 Our findings indicate that olfaction affects adult physiology and aging in Drosophi

53 re from existing methodologies in artificial olfaction, allows the recognition module to better mitig

54 ofessionals under two conditions: orthonasal olfaction alone and global tasting.

55 Olfaction also enables stimulus categorization and gener

56 inal projections onto regions concerned with olfaction and audition.

57 genes with roles in sex steroid metabolism, olfaction and drug response.

58 Similar olfaction and electroolfactogram defects were found in o

59 Here, we report defective olfaction and electroolfactogram responses in AQP4-null

60 Olfaction and gustation play critical roles in the life

61 In particular olfaction and hearing may have played an important role

62 ity, bone remodeling, synaptic transmission, olfaction and hearing.

63 ers sharing overlapping features of impaired olfaction and hypogonadism.

64 ucosa, a site where the complex functions of olfaction and immunity need to be orchestrated.

65 s probably driven by increased resolution in olfaction and improvements in tactile sensitivity (from

66 s and fluid, to sensory inputs involved with olfaction and photoreception.

67 siological function of Hedgehog signaling in olfaction and provide an important evolutionary link bet

68 strong evidence for temporal integration in olfaction and puts a constraint on models of olfactory p

69 le in regulating many behaviors that rely on olfaction and recently there has been great effort in de

70 dministration, followed by the assessment of olfaction and reward-driven snack intake in the absence

71 indicate that certain conditions that impact olfaction and sexual development, such as Kallmann syndr

72 , neurological screening reveals deficits in olfaction and social dominance.

73 Here, we show a combined effect of olfaction and social hierarchy on micturition patterns i

74 Olfaction and some forms of taste (including bitter) are

75 lutionary novelties for beak development and olfaction and specifically for homeostasis-related genes

76 redefine the role of sorption properties in olfaction and suggest that the peripheral olfactory syst

77 transmitters as well as the senses of sight, olfaction and taste.

78 fy and locate their mates, primarily through olfaction and taste.

79 ovide an important evolutionary link between olfaction and the requirement of a ciliary compartment f

80 odel to evaluate the specific role of MCs in olfaction and to test the restorative function of transp

81 Although olfaction and vision contribute to food detection, the g

82 lad over wild hosts, and whether the role of olfaction and vision in response to cues from host plant

83 Examples abound from sensory systems like olfaction and vision.

84 s changes in some brain areas concerned with olfaction and voice perception consistent with sexual id

85 severe bladder/bowel dysfunction, preserved olfaction, and a cardiac chronotropic response upon tilt

86 he interactions between taste and retronasal olfaction, and a paradigm for enhancing liking of natura

87 antidepressant fluoxetine (FLX) on behavior, olfaction, and adult neurogenesis in the dentate gyrus (

88 evalent among genes associated with defense, olfaction, and among genes downstream of the Drosophila

89 mily, widely studied in insect gustation and olfaction, and are implicated in host-seeking by insect

90 al physiological roles in phototransduction, olfaction, and cardiac pace making.

91 an thus be used to better understand natural olfaction, and it also suggests ways to improve artifici

92 via coding changes is dominated by immunity, olfaction, and male reproduction.

93 th these wide clines include cell signaling, olfaction, and pheromone response.

94 es in biological processes including vision, olfaction, and skin pigmentation.

95 blebee chemoreception towards gustation from olfaction, and striking differences in microRNAs, potent

96 for sensory processes, e.g., photoreception, olfaction, and taste.

97 g sequences of genes critical for cognition, olfaction, and thermotolerance, consistent with the obse

98 physically and/or chemically interfere with olfaction, and thus maintains the olfactory acuity of th

99 ys of non-specific biosensors for artificial olfaction applications.

100 Disorders of olfaction are among the first clinical signs of neurodeg

101 Thus, key components of olfaction are expressed in the renal distal nephron and

102 nd suggest that impacts of neonicotinoids on olfaction are greater than their effects on rewarding me

103 Ortho- and retronasal olfaction are particularly crucial to flavor because the

104 rliest hypothesis of the role of sniffing in olfaction arises from the fact that odorants with differ

105 neurons that have been implicated in normal olfaction as well as in Parkinson's disease.

106 ence of correlated transformations affecting olfaction as well as mastication, head movement, and ven

107 We examine interactions between taste and olfaction as well as psychophysical measurement limitati

108 odorant mixtures, "whiteness" may emerge in olfaction as well.

109 derives not from empirical studies of human olfaction but from a famous 19th-century anatomist's hyp

110 It locates its human hosts primarily through olfaction, but little is known about the molecular basis

111 R) superfamily is best known for its role in olfaction, but virtually nothing is known about a clade

112 the limits of temporal resolution in insect olfaction by delivering high frequency odor pulses and m

113 factory epithelium and are thought to affect olfaction by enzymatic conversion of odorant molecules.

114 Electronic olfaction can be successfully used in the analysis of ed

115 Impaired olfaction can predate clinical PD in men by at least 4 y

116 interneurons, GH298 and krasavietz, leads to olfaction changes toward attraction or repulsion, while

117 In olfaction, changes in the concentration of a given odor

118 s, autonomic and psychiatric manifestations, olfaction, color vision, sleep parameters, and neurocogn

119 ine minerality scores only in the orthonasal olfaction condition, samples from the left being more mi

120 Understanding the molecular basis of insect olfaction could facilitate the development of interventi

121 As such, olfaction could have great potential as an early biomark

122 Galpha(olf) plays a role in olfaction, coupling D1 and A2a receptors to adenylyl cyc

123 roxyurea (HU) treatment results in a loss of olfaction-dependent increase in yaw optomotor fidelity.

124 Olfaction depends on the differential activation of olfa

125 Olfaction depends on the selectivity and sensitivity of

126 virtue of the potentially important role of olfaction during neocortical evolution.

127 pecies that primarily use other senses (e.g. olfaction, echolocation), and suppression was strongest

128 However, mechanisms underlying olfaction-emotion interaction remain unclear, especially

129 To help understand how olfaction evolves in Caenorhabditis and to examine patte

130 nt odor molecules; gene families involved in olfaction exhibit high diversity in different animal phy

131 s, suggesting functionality of SiOBPs beyond olfaction Expression patterns of SiOBP subgroups also sh

132 Male flies deficient for olfaction failed to perform the locomotion-dependent son

133 sory neurons (OSNs), which are essential for olfaction (Figure 1).

134 Many species are critically dependent on olfaction for survival.

135 Recent studies of locust olfaction found that the responses of individual second

136 Although olfaction has a significant role in determining food fla

137 In contrast, research in olfaction has focused almost exclusively on how the nerv

138 Olfaction has often been described as a 'synthetic' sens

139 Functional imaging studies of olfaction have consistently reported odorant-induced act

140 n and metabolism, as well as those affecting olfaction, have reduced gene expression in Drosophila se

141 Vision, olfaction, hearing, and balance are mediated by receptor

142 s and the endosseous labyrinth suggests that olfaction, hearing, and equilibrium were well-developed

143 as key biological sensors in vision, taste, olfaction, hearing, and touch.

144 hich include contributions to vision, taste, olfaction, hearing, touch, and thermo- and osmosensation

145 Despite their importance in olfaction, how most Olfr mRNAs are regulated remains une

146 euronal stimulus selectivity in systems like olfaction, however, which lack a simple two-dimensional

147 neurons has facilitated our understanding of olfaction; however, many other AL neurons remain unident

148 lty, sweet, sour, bitter, umami), retronasal olfaction (i.e. smelling through the mouth), and somatos

149 under positive selection and are involved in olfaction, immune response, development, locomotion, and

150 wide variety of biological processes such as olfaction, immunity, and gene regulation.

151 faction in larvae to semiaquatic or airborne olfaction in adults requires anatomical, cellular, and m

152 gene family is absent from S. maritima, and olfaction in air is likely effected by expansion of othe

153 Behavioral analysis showed greatly impaired olfaction in AQP4-null mice, with latency times of 17 +/

154 and examined a novel intervention to improve olfaction in ESRD.

155 We therefore investigated olfaction in human subjects from families with congenita

156 We found severe defects in olfaction in individuals with CHD7 mutations and CHARGE,

157 The transition from aquatic olfaction in larvae to semiaquatic or airborne olfaction

158 lar and organizational strategies underlying olfaction in mice.

159 and recognition of conspecifics that rely on olfaction in most species.

160 Olfaction in moths is one of the most impressive example

161 Olfaction in particular depends strongly on active sensi

162 rogress has been made in the field of insect olfaction in recent years.

163 Olfaction in rodents provides an excellent modality for

164 erceptual boundaries through evolution, from olfaction in rodents to visual memory in humans.

165 ystem scaling in vertebrates, the primacy of olfaction in spatial navigation, even in visual speciali

166 lecular and cellular mechanisms underpinning olfaction in teleosts and mammals are similar despite 43

167 t does not seem to reflect the importance of olfaction in the biology of the Atlantic salmon.

168 l variation and indicate the significance of olfaction in the regulation of reproductive decline duri

169 significance of this feedback mechanism for olfaction in vivo, we genetically mutated serine(1076) o

170 s thought to play several important roles in olfaction, including maintaining the sparseness of respo

171 We find that major components of olfaction, including olfactory receptors (ORs), olfactor

172 d visceral/autonomic information, taste, and olfaction influence behavioral responses mediated by the

173 itional, action-based perspective focuses on olfaction instead of on vision and is descriptive (descr

174 Here, we test the hypothesis that taste and olfaction interact in the nucleus of the solitary tract

175 emotional disorders, as exaggerated emotion-olfaction interaction in negative mood states turns inno

176 Peripheral events in olfaction involve odorant binding proteins (OBPs) whose

177 Olfaction is a key insect adaptation to a wide range of

178 Artificial olfaction is a potential tool for noninvasive chemical m

179 ponents of odorant mixtures, suggesting that olfaction is a synthetic sense in which mixtures are per

180 Olfaction is a vitally important sense for all animals.

181 The target article's emphasis on olfaction is a welcome reminder of the multimodal nature

182 Olfaction is an integral part of feeding providing predi

183 Phylogenetically the most ancient sense, olfaction is characterized by a unique intimacy with the

184 Olfaction is considered a distance sense; hence, aquatic

185 Retronasal olfaction is crucial for the perception of food flavor i

186 Olfaction is crucial for the reproductive success of par

187 s in Chd7 deficient mice, suggesting reduced olfaction is due to a dysfunctional olfactory epithelium

188 Olfaction is generally assumed to be critical for surviv

189 An intriguing question in the field of olfaction is how animals distinguish among structurally

190 Because olfaction is linked with ingestive behavior to guide foo

191 Olfaction is mediated by the binding of odorant molecule

192 nformation inherent in the olfactory signal, olfaction is more involved in interpreting space and tim

193 Whether olfaction is most suitable as a model system to study co

194 If instead the primary function of olfaction is navigation, i.e., predicting odorant distri

195 derive from assuming the primary function of olfaction is odorant discrimination and acuity.

196 The role of insulin pathways in olfaction is of significant interest with the widespread

197 Although olfaction is often compromised by such factors as head t

198 completely overlooked, despite the fact that olfaction is one of the first sensory modalities to deve

199 Olfaction is one of the most crucial senses for vertebra

200 nitive and memory functions, but its role in olfaction is poorly understood.

201 taxa with short nonfeeding adults, in which olfaction is redundant.

202 Olfaction is required at birth for survival; however, li

203 the most fundamental tenets in the field of olfaction is that each olfactory receptor neuron (ORN) e

204 The current consensus model in mammalian olfaction is that the detection of millions of odorants

205 For many insects, including mosquitoes, olfaction is the dominant modality regulating their beha

206 considered a distance sense; hence, aquatic olfaction is thought to be mediated only by molecules di

207 Olfaction is thought to play an important role in the ho

208 It is well established that Drosophila olfaction is under circadian control, yet the mechanisms

209 g ability but it is unknown what the role of olfaction is when birds navigate freely without their se

210 A fundamental question in olfaction is which odorant receptors (ORs) are activated

211 In olfaction, just a few studies have addressed the issue o

212 ed roles in a variety of functions including olfaction, learning and mood regulation.

213 The results imply that olfaction, like all other sensory modalities, requires a

214 espite the critical role of granule cells in olfaction, little is known about how sensory input recru

215 receptors (GPCRs), as well as the canonical olfaction machinery (Golf and AC3) in the smooth muscle

216 , spatial orientation, memory retrieval, and olfaction may explain some of the common disturbances in

217 s in defining the basic mechanisms of insect olfaction may lead to means of disrupting host-seeking a

218 In addition, the unique percepts of olfaction may organize odorant information in a parallel

219 nd suggest that the poor reputation of human olfaction may reflect, in part, behavioral demands rathe

220 Thus, olfaction may serve as a useful biomarker to both follow

221 C. elegans TRPV channels function in olfaction, mechanosensation, osmosensation, and activity

222 Finally, we show that olfaction mediates the efficient recognition of yeast as

223 anding our knowledge of the role of Kv1.3 in olfaction, metabolism, and axon targeting.

224 Here, we show that olfaction modulates reproductive timing and senescence t

225 ses were confirmed to result from retronasal olfaction: monitoring respiration revealed that exhalati

226 ur findings identify a role for the TAARs in olfaction, namely, in the high-sensitivity detection of

227 In olfaction, new behavioural evidence in rodents has provi

228 ic hypogonadotropic hypogonadism with normal olfaction (nIHH).

229 pid scramblases and ion channels involved in olfaction, nociception, and blood coagulation.

230 We investigated olfaction-nutrition associations in these participants a

231 rstanding of olfactory impairment and of the olfaction-nutrition axis in patients with kidney disease

232 a) and non-motor symptoms (eg, cognition and olfaction) of LRRK2-associated PD were more benign than

233 We propose that, in addition to its role in olfaction, Olfr78 acts as a hypoxia sensor in the breath

234 The dependence of olfaction on inhalation also allows for profound modulat

235 the basis for the perceptual differences in olfaction or whether disease-specific or other entities,

236 iminish learned fear, anxiety-like behavior, olfaction, or nonaversive learning.

237 ng in the Azores indicated a crucial role of olfaction over the open ocean, but left open the questio

238 ns (OBPs) are thought to involve in insects' olfaction perception.

239 s, communication at a distance by vision and olfaction, photosymbiosis, chemosymbiosis, suspension fe

240 important for transepithelial ion transport, olfaction, phototransduction, smooth muscle contraction,

241 nd physiology suggests that ortho-retronasal olfaction played a critical role at three stages of mamm

242 In insects, olfaction plays a crucial role in many behavioral contex

243 Olfaction plays a dominant role in the mate-finding and

244 nted odors in at-sea trials, suggesting that olfaction plays a role in natural foraging behavior.

245 nhaling air through the nostrils, suggesting olfaction plays an important role in aquatic foraging.

246 therefore organized the crowd-sourced DREAM Olfaction Prediction Challenge.

247 The presence of SAT in olfaction provides strong evidence for temporal integrat

248 iated genomic regions are highly enriched in olfaction-related genes, indicating a role of nuclear or

249 overall there is relaxed constraint on human olfaction relative to chimpanzee, species-specific senso

250 ate, their physiological functions in insect olfaction remain largely controversial in comparison to

251 et its effects on olfactory neurogenesis and olfaction remain unknown.

252 of spatial integration of neural activity in olfaction remains unclear.

253 Nonetheless, its role in olfaction remains unclear.

254 r, much of the systems-level organization of olfaction remains unexplored.

255 However, the cerebellar role in olfaction remains unknown.

256 the influence of taste (gustation) on odor (olfaction) remains essentially unknown.

257 iple measures of social interactions, social olfaction, repetitive behaviors, anxiety-related behavio

258 Olfaction requires both ligands for signaling and sensor

259 criminate odors in one breath, and mammalian olfaction research has thus focused on the first breath.

260 Drosophila, an important model organism for olfaction research.

261 Comparison of rodent, insect and nematode olfaction reveals surprising differences and unexpected

262 ients had reduced CSF amyloid Ass1-42, lower olfaction scores, higher depression scores and increased

263 d 10 distinct communication behaviours, with olfaction, scraping, and cheek rubbing the most frequent

264 In olfaction, sensory input activity is initially processed

265 und in brain regions known to be involved in olfaction, somatic motor control, fluid homeostasis, ing

266 r of the five major sensory systems (vision, olfaction, somatosensation, and audition) are thought to

267 n pangolins, reflecting their well-developed olfaction system.

268 iety of systems, including vision, audition, olfaction, taste and electric sense.

269 tionnaires, quantitative sensory testing and olfaction testing during the in-clinic phase of the stud

270 Olfaction testing using the Sniffin'T test did not demon

271 e of clinical PD and dementia at the time of olfaction testing.

272 vor is produced by the integration of taste, olfaction, texture, and temperature, currently thought t

273 lts establish AQP4 as a novel determinant of olfaction, the deficiency of which probably impairs extr

274 In olfaction, the main question is whether habituation work

275 bility of genomic and genetic tools to study olfaction-the sense of smell-has brought important new i

276 pment was driven in part by ortho-retronasal olfaction; the bauplan for neocortex had higher-level as

277 In both gustation and olfaction, these differences were driven primarily by tr

278 including locomotion, aversive learning and olfaction through at least four different 5-HT receptors

279 s in the nasal mucus, and they contribute to olfaction through various mechanisms.

280 ing a complete switch of calyx modality from olfaction to vision.

281 reat functional diversity including roles in olfaction, transportation, and prostaglandin synthesis i

282 e, it is widely held that mammals cannot use olfaction underwater because it is impossible for them t

283 behaviour provides a mechanism for mammalian olfaction underwater.

284 re contains contradictory claims that insect olfaction uses cAMP, cGMP, or IP3 as second messengers;

285 ion/translation, metabolism, detoxification, olfaction, vision, cuticle regulation, and immunity, and

286 of inputs from different sensory modalities (olfaction, vision, thermosensation), we conclude that th

287 ulu-Asia Aging Study cohort members METHODS: Olfaction was assessed from 1991 to 1996 in 2,267 men in

288 Olfaction was assessed in affected subjects and Lewy bod

289 Olfaction was tested for all subjects in upright and 6 d

290 ive biochemistry and molecular mechanisms of olfaction, we have developed a mammalian expression syst

291 the relationship between gene expression and olfaction, we have performed cohort comparisons of anten

292 ons, relative-reinforcing value of food, and olfaction were measured at days 1 and 4.

293 ls to smell others' mouths and determine via olfaction what foods their conspecifics had chosen.

294 cilia, the essential signaling platform for olfaction, which alters the uniformity of responses in p

295 st to mammalian chemosensation or Drosophila olfaction, which are initiated by receptors composed of

296 ate disparate modalities, such as vision and olfaction, which are neither related by spatiotemporal s

297 Olfaction, which is an important physiological function

298 ce and worms leads to profound impairment in olfaction, while similar mutations in the fly show more

299 ve seen significant advances in the study of olfaction, with particular emphasis on elucidating the m

300 trasonic vocalizations, but displayed normal olfaction, working and reference memory, motor abilities