ライフサイエンスコーパス: orf

1 otein encoded by KSHV open reading frame 65 (orf 65) to develop a diagnostic enzyme-linked immunosorb

2 pletion of the protein encoded by 44 TetO(7)-orf strains resulted in mislocalized GFP-Nic96.

3 om a doxycycline-regulated promoter (TetO(7)-orf).

4 The orf-A (orf-2) gene of feline immunodeficiency virus (FIV) is a

5 ert (1810 bp) revealed a 256-amino-acid (aa) orf.

6 ther regions of the viral genome (orf 72 and orf 75) was uniformly negative for all MM and control sa

7 Bovine papular stomatitis virus (BPSV) and orf virus (ORFV), members of the genus Parapoxvirus of t

8 Both isp and orf are highly conserved among strains of GAS, as shown

9 evealed two small downstream genes, parB and orf-84, of which only parB was found to be essential for

10 (pCMVJS21DeltaGP) in which the gag, pol (and orf-x) coding sequences were deleted also gave transform

11 (pathogenicity island-encoded proteins) and orf, in addition to sopB.

12 e coding for the enzyme was identified to be orf 225 or nfi (endonuclease five).

13 ull length-mouse XPC cDNA contains a 2703 bp orf which encodes a polypeptide containing 900 amino aci

14 sitive, at about the limit of detection, but orf 26 sequence was also amplified from 11 of 25 (44%) h

15 ong HIV-infected gay men without KS (5/16 by orf 65 ELISA, 10/33 by IFA), HIV-uninfected STD clinic a

16 and Ugandan HIV-uninfected controls (6/17 by orf 65 ELISA, 9/17 by IFA).

17 dine-sensitive promoter upstream of the carA-orf-carB-greA operon.

18 open reading frames, a previously described orf and a new locus, isp (immunogenic secreted protein),

19 When the entire orf* gene was sequenced, it was found to encode a protei

20 the atypical open reading frames (ORFans) F-orf and M-orf, respectively inside F and M mtDNAs, which

21 Open reading frame (orf) 72 encodes a D type cyclin (kcyc) that can elicit p

22 which an unusually large open reading frame (orf) of 5005 amino acids can be deduced.

23 A fragment containing an open reading frame (orf), that we refer to as the radA gene, for each of the

24 e linker to generate one open reading frame (orf).

25 ll retroviral integrase open reading frames (orf), despite the divergence in the primary sequences.

26 In addition, virions derived from orf-A mutant proviruses expressed reduced infectivity fo

27 to known recombination and repair functions, orf partially suppressed the UV sensitivity of ruvAB and

28 The modBC gene comprised a fused orf including components corresponding to modB and modC

29 (LNA) which is the product of the viral gene orf 73.

30 acid match with a partially sequenced gene (orf*) of R. leguminosarum.

31 tion from other regions of the viral genome (orf 72 and orf 75) was uniformly negative for all MM and

32 Three open reading frames were identified: orf, whose function is unknown; divIVA; and isoleucyl tR

33 these mutants were determined (base 3546 in orf 4 for strain 281.25 and base 4402 in orf 5 for strai

34 in orf 4 for strain 281.25 and base 4402 in orf 5 for strain 276.4), and the effects of these mutati

35 Deletions and point mutations in orf-A imposed a small effect or no effect on FIV long-te

36 hese data support the identification of KSHV orf 73 as the gene encoding the dominant immunogenic com

37 sera from KS patients reacted with the KSHV orf 65 protein and 84/103 (81.5%) reacted with KSHV late

38 cal open reading frames (ORFans) F-orf and M-orf, respectively inside F and M mtDNAs, which are hypot

39 ed and diverged atp8 gene evolved into the M-orf associated with the paternal transmission route in H

40 conditions, suggesting that neither isp nor orf is involved in the Mga regulatory circuit.

41 Here, the novel orf virus (ORFV)-encoded protein ORFV002 was shown to in

42 his case, this is the first reported case of orf virus infection in a skin graft harvest.

43 The dominant immunogenic region of orf 65 is within the carboxyterminal 80 aminoacids, a re

44 Among these, however, only orf 73, when expressed in heterologous mammalian cell sy

45 The parapoxvirus orf virus (ORFV) is a pathogen of sheep and goats that h

46 1 integrase is functional in the SNV gag-pol orf with a lower transduction efficiency, utilizing homo

47 However, an alternate ORF in pol (orf-x) might be a candidate for a transforming gene.

48 Finally, seroreactivity with recombinant orf 73 protein exactly paralleled reactivity with classi

49 cells sustaining a deletion of prgU, a small orf located immediately downstream of prgB on pCF10.

50 second gene in an operon with a second small orf, which we have termed sspN.

51 related Epstein-Barr virus, suggesting that orf 65 is a KSHV specific antigen.

52 The orf gene of bacteriophage lambda, fused to a promoter, w

53 The orf-A (orf-2) gene of feline immunodeficiency virus (FIV

54 The orf-I gene of human T-cell leukemia type 1 (HTLV-1) enco

55 for HHV-8 sequence using PCR to amplify the orf 26 (KS330) sequence, as initially reported.

56 thermore, extracts from cells expressing the orf 73 protein product specifically blocked the binding

57 aphy analysis of quinones extracted from the orf-complemented cells independently confirmed the resto

58 s (2/63) had KSHV specific antibodies in the orf 65 assay whereas none of these sera reacted with lat

59 he introduction of the menA product into the orf-complemented menA mutant.

60 Antibody reactivity to the orf 65 protein (ELISA) and to latent antigen(s) (IFA) wa

61 f a mutated version of pCMVJS21 in which the orf-x protein was terminated by two stop codons also gav

62 DNA sequence analysis grouped this orf virus isolate among isolates from India.

63 Thus, orf-x was eliminated as the candidate transforming gene.

64 Compared to orf, the recA803 allele had only small effects on recF,

65 Antibodies to latent antigen(s) or to orf 65 encoded capsid protein will not detect all cases

66 C, the bio gene cluster, and an unidentified orf.

67 nd 4/150 with latent antigen; US, 6/117 with orf 65 and 0/117 with latent antigen).

68 blood donors by either assay (UK, 3/174 with orf 65 and 4/150 with latent antigen; US, 6/117 with orf

69 in supernatants from cells transfected with orf-A mutant proviruses was severely restricted but was

70 Deletions within orf-A severely restricted FIV replication in feline peri

71 n-frame deletions and point mutations within orf-A were constructed and tested for replication in fel