ライフサイエンスコーパス: pathological mechanism

1 mation and provides new insights for the nGD pathological mechanism.

2 e and pseudo-hypoxia has been suggested as a pathological mechanism.

3 was activated in mutant mice, identifying a pathological mechanism.

4 determination, and our understanding of its pathological mechanism.

5 e results provide insight into its potential pathological mechanism.

6 rden of subclinical infections and elucidate pathological mechanisms.

7 iated MG may be different in etiological and pathological mechanisms.

8 NA level have all been suggested as possible pathological mechanisms.

9 ential hypertension results from a mosaic of pathological mechanisms.

10 s reflecting the heterogeneity of underlying pathological mechanisms.

11 nd dementia, and to both shared and distinct pathological mechanisms.

12 ttle is known about its involvement in other pathological mechanisms.

13 al signs and is likely caused by an array of pathological mechanisms.

14 nstrumental for the further understanding of pathological mechanisms.

15 t understanding of HTT function and the main pathological mechanisms.

16 nical p38 pathway regulated SMC apoptosis, a pathological mechanism also governed by Kruppel-like fac

17 a significant clinical problem; however, its pathological mechanism and effective treatments remain e

18 Pathological mechanisms and potential treatments for ON

19 condary tauopathy, neither the cause nor the pathological mechanisms and repercussions are understood

20 may advance our understanding of underlying pathological mechanisms and the complex relationship bet

21 The pathological mechanisms and the related immunological pa

22 ersus microscopy in PSP may reflect distinct pathological mechanisms, and elucidation of these proces

23 hole exome sequencing results, insights into pathological mechanisms, and possible therapies will hin

24 diverging function of each isoform and what pathological mechanisms are activated upon their loss re

25 of neonatal morbidity and mortality, but its pathological mechanisms are largely unknown.

26 s and its position in the gene, two possible pathological mechanisms are proposed: (1) the protein ma

27 ve impairment but the responsible underlying pathological mechanisms are unknown.

28 ry of Abeta will allow speedy delineation of pathological mechanisms associated with specific neurode

29 This study describes a new molecular pathological mechanism by which a silent mutation inhibi

30 The pathological mechanism by which Abeta causes neuronal dy

31 cases, have been described recently, but the pathological mechanism by which causal mutations result

32 ce has allowed investigators to evaluate the pathological mechanisms by which different genes influen

33 As yet, the pathological mechanisms connecting mutant Rab7 protein e

34 ement of resurgent currents may constitute a pathological mechanism contributing to sensory neuron hy

35 Connecting diseases with similar pathological mechanisms could inspire novel strategies o

36 The exact pathological mechanisms determining disease onset and pr

37 evaluated for their potential in determining pathological mechanisms, elucidating therapeutic health

38 r cells, these observations suggest a likely pathological mechanism for IMPDH1-mediated hereditary bl

39 eceptor target for GRK2 and represents a new pathological mechanism for this kinase in the failing he

40 eptides has been considered one of the major pathological mechanisms for Alzheimer disease.

41 interest in using EM in understanding novel pathological mechanisms for different subtypes of asthma

42 Aging and oxidative stress are two prominent pathological mechanisms for Parkinson's disease (PD) tha

43 he infectious triggers and immunological and pathological mechanisms has advanced substantially in th

44 Although the pathological mechanisms have not been definitively eluci

45 lity to EBV infection, though the underlying pathological mechanisms have not yet been identified.

46 c Ca(2+)-permeable membrane pores is a major pathological mechanism in AD and introduce TIRF imaging

47 cytotoxic, potentially representing a novel pathological mechanism in AD which may be further exacer

48 mation has been increasingly implicated as a pathological mechanism in dementia and demonstration tha

49 nded polyglutamine is thought to be a common pathological mechanism in HD and other glutamine repeat

50 ecies production has emerged as an important pathological mechanism in myocardial ischemia/reperfusio

51 indicating that intravascular hemolysis is a pathological mechanism in several human diseases, includ

52 These diseases have many pathological mechanisms in common, and there may be rela

53 implicate dysregulation in these pathways as pathological mechanisms in HD.

54 ered SC lipid metabolism are thus underlying pathological mechanisms in mitochondria-related peripher

55 To study novel pathological mechanisms in neuronopathic Gaucher disease

56 use infection model presents new findings on pathological mechanisms in the colon.

57 the regulation of LD turnover and potential pathological mechanisms in Troyer syndrome.

58 stem may be compensatory, rather than purely pathological, mechanisms in certain contexts.

59 These pathological mechanisms interfere with vessel patency th

60 including HSP70 and HSP90, key regulators of pathological mechanisms involved in diabetes complicatio

61 The pathological mechanisms involved in ocular VACV infectio

62 ese results open avenues for deciphering the pathological mechanisms involved in pigmentation disease

63 These pigments are implicated in pathological mechanisms involved in several vision-threa

64 These pigments are implicated in pathological mechanisms involved in some vision-threaten

65 s (after expression of myogenin) or that the pathological mechanisms involved in these neoplasms also

66 ing developed in an effort to understand the pathological mechanisms involved.

67 llectively, these findings delineate a novel pathological mechanism involving aberrant APP processing

68 tures and data presented here suggest that a pathological mechanism involving abnormal cholesterol tr

69 s information might shed light on underlying pathological mechanisms involving inflammation and could

70 y that arises and despite many theories, the pathological mechanism is not fully understood.

71 ata, we propose oxidative stress as a common pathological mechanism leading to PVI impairment in schi

72 in DS/AD and sporadic AD brains, converging pathological mechanisms leading to chronic oxidative str

73 Mitotic perturbations can contribute to pathological mechanisms leading to cortical malformation

74 Pathological mechanisms occurring in this disease have n

75 ation approved agent to treat the underlying pathological mechanism of chronic dry eye, has demonstra

76 on may therefore provide a model for a novel pathological mechanism of Duchenne muscular dystrophy an

77 The pathological mechanism of IBMPFD is not clear and there

78 eakpoint has prognostic utility and that the pathological mechanism of mapping to an R-band cannot be

79 afish model of what is potentially the novel pathological mechanism of muscle attachment failure in D

80 rophic lateral sclerosis (ALS); however, the pathological mechanism of PFN1 in this fatal disease is

81 his study provided critical insight into the pathological mechanism of psychological suboptimal healt

82 ACE1, treatments that address the underlying pathological mechanisms of AD are still lacking.

83 the lung, which is not only relevant to the pathological mechanisms of ARDS, but might also represen

84 primate disease models for understanding the pathological mechanisms of brain disorders and for devel

85 and DCs may collaborate with T cells in the pathological mechanisms of coronary arteritis.

86 uch regulatory systems may contribute to the pathological mechanisms of degenerative motor neuron dis

87 atment of symptoms but also on targeting the pathological mechanisms of disease, ideally before sympt

88 r future investigations of physiological and pathological mechanisms of exosome biogenesis, protein t

89 Understanding the pathological mechanisms of fibrosis in the kidney and ot

90 l identifies a novel strategy to explore the pathological mechanisms of HSAN1.

91 individual patient and provide insight into pathological mechanisms of human disease.

92 which to test competing hypotheses regarding pathological mechanisms of inflammation in NEC, suggest

93 t of the cilium and provide insight into the pathological mechanisms of LCA and related ciliopathies.

94 The pathological mechanisms of LST were as follows: (1) sten

95 The classification and pathological mechanisms of many central nervous system i

96 contrast the underlying disease networks and pathological mechanisms of monogenic as opposed to compl

97 Hepatic metabolomic studies yielded multiple pathological mechanisms of NAFLD.

98 ts ErbB receptors has been implicated in the pathological mechanisms of schizophrenia, loss of Nrg1 m

99 AD) improves distorted cardiac geometry, the pathological mechanisms of the "reverse remodeling" of t

100 eptibility/resistance to MD and defining the pathological mechanisms of the disease gives us a much g

101 fers many new avenues for investigation into pathological mechanisms of the disease, with implication

102 These studies may shed light on the pathological mechanisms of these diseases, with implicat

103 ients with DNO, which supports the different pathological mechanisms of these diseases.

104 Recent advances in our understanding of the pathological mechanisms of thrombotic thrombocytopenic p

105 odulators simultaneously addressing multiple pathological mechanisms or overcoming pathway robustness

106 Regardless of the underlying pathological mechanisms oxidative stress seems to be pre

107 ular disease, most causes share an important pathological mechanism: oxidative stress.

108 he biochemical, cellular, physiological, and pathological mechanisms regulated by PREPL.

109 subsequent renal failure, but the underlying pathological mechanisms remain elusive.

110 henne muscular dystrophy (DMD); however, the pathological mechanisms remain largely unknown.

111 sease, remodeling, and heart failure but the pathological mechanisms remain obscure.

112 nge is related to cell swelling, the precise pathological mechanism remains elusive.

113 endosomal/lysosomal pathways, but the exact pathological mechanism remains poorly understood.

114 risk factor for dementia, but the associated pathological mechanisms remains unclear.

115 r in Huntington's disease (HD), one putative pathological mechanism reported to play a prominent role

116 an cerebral cortex development, and that the pathological mechanism resulting from the mutations we d

117 I, there is an urgent need to understand the pathological mechanism(s) involved on a neurobiological,

118 cause dilated cardiomyopathy through unknown pathological mechanism(s).

119 Very little is known about the pathological mechanisms that are involved, and the infor

120 in translating the human genetic findings to pathological mechanisms that are translatable back to th

121 A better understanding of the pathological mechanisms that drive neurodegeneration in

122 h stable IHD does not address the underlying pathological mechanisms that lead to the progression of

123 ing may be attributable to a reversal of the pathological mechanisms that occur in remodeling or the

124 fatty acids (PUFAs) could target some of the pathological mechanisms that underlie damage after SCI.

125 The pathological mechanisms that underlie T helper type 2 ce

126 e results further demonstrate that different pathological mechanisms underlie PCP-induced neuronal da

127 We hypothesized that the pathological mechanism underlying SAP-IFN-gamma cardiomy

128 Vascular response is an essential pathological mechanism underlying various inflammatory d

129 in the esophagus, as well as in elucidating pathological mechanisms underlying BA and CA.

130 diate link between overnutrition and certain pathological mechanisms underlying cardiovascular diseas

131 n measurements can be used to understand the pathological mechanisms underlying disease processes.

132 Identification of the pathological mechanisms underlying GBA-associated parkin

133 The pathological mechanisms underlying neurological deficits

134 In order to identify pathological mechanisms underlying NPC and uncover poten

135 networks to give a novel perspective on the pathological mechanisms underlying Parkinson's disease d

136 Specific pathological mechanisms underlying symptoms have not yet

137 The pathological mechanisms underlying these toxicities are

138 Pathological mechanisms underlying ventricular enlargeme

139 hus, tau mutations cause FTDP-17 by multiple pathological mechanisms, which may explain the phenotypi

140 anding the complexity of complement-mediated pathological mechanisms will aid in the development of a