ライフサイエンスコーパス: pathomechanism

1 and ciliary body edema may play role in the pathomechanism.

2 o psoriasis rather than any knowledge of its pathomechanism.

3 s in these regions that might be relevant to pathomechanism.

4 of these transcripts will most likely inform pathomechanism.

5 otrophic and can interact with more than one pathomechanism.

6 e of FLUX-reacting T cells in the underlying pathomechanism.

7 neovascular ("wet") AMD, suggesting a common pathomechanism.

8 firm our findings and explore the underlying pathomechanism.

9 n in mice through different gain of function pathomechanisms.

10 eases and how these structures contribute to pathomechanisms.

11 levance of PI in CSU and we discuss possible pathomechanisms.

12 ient treatment modality interfering with GPP pathomechanisms.

13 and postictal arrhythmias suggest different pathomechanisms.

14 epresent different genetic and environmental pathomechanisms.

15 erosis, which both involve macrophage-driven pathomechanisms.

16 ferent fibrotic diseases also have different pathomechanisms.

17 tic uremic syndrome (aHUS) in the underlying pathomechanisms.

18 cellular phenotype and suggesting different pathomechanisms.

19 dentifying its causes, eliciting factors and pathomechanisms.

20 essive forms of OI suggests common molecular pathomechanisms.

21 This study reveals a novel pathomechanism affecting muscle regeneration and mainten

22 se in turn have the potential to both inform pathomechanism and assist in the rational molecular clas

23 genesis is an important clue to decipher the pathomechanism and develop efficient therapies.

24 There is a marked heterogeneity of the pathomechanism and development of hereditary angioedema

25 ma oscillation may have implications for the pathomechanism and treatment of cognitive impairment in

26 mal model that can be used to define disease pathomechanisms and biologically important domains withi

27 ed by discussions of the anatomy, underlying pathomechanisms and clinical significance of individual

28 monstrate that astrocytes are central in VWM pathomechanisms and constitute potential therapeutic tar

29 To explore pathomechanisms and develop new preclinical treatment ap

30 el 4 (BSL-4) facility, little is known about pathomechanisms and host interactions.

31 to regenerated human tissue can thus dissect pathomechanisms and identify targets that reverse diseas

32 improve the understanding of the underlying pathomechanisms and identify the optimal dosing for the

33 developments concerning the potential viral pathomechanisms and involvement of viruses in Sjogren's

34 These findings provide insight into pathomechanisms and may have therapeutic relevance for t

35 Localising these pathomechanisms and processes within and across differen

36 However, their underlying pathomechanisms and regulation of RAN translation remain

37 The presented concept elucidates diverse pathomechanisms and risks of malignancies in patients wi

38 nges in autism spectrum disorder may clarify pathomechanisms and thereby help identify targets for dr

39 Rodent models are useful to dissect pathomechanisms and to develop treatment strategies.

40 , it is possible that pore leak represents a pathomechanism applicable to many channel diseases.

41 Its cause and pathomechanism are not fully known.

42 n individuals develop MDH and the underlying pathomechanism are unclear.

43 lasia, although their cellular and molecular pathomechanisms are not precisely known.

44 The key underlying pathomechanisms are unclear.

45 fore, a pressing need to identify innovative pathomechanism-based effective therapies for this condit

46 Neuroinflammation is implicated as a pathomechanism, but the upstream mechanisms driving glio

47 s are the key initial events of the cellular pathomechanisms by carrying out a detailed developmental

48 s are the key initial events of the cellular pathomechanisms by carrying out a detailed developmental

49 The understanding of the pathomechanisms by which these mutations produce phenoty

50 The underlying pathomechanisms can affect numerous pathways involved in

51 ue cytokine production suggests that several pathomechanisms can modulate the expression of the immun

52 hat they group into three distinct molecular pathomechanisms: class 1 ATF6 mutants show impaired ER-t

53 -contraction coupling, providing a potential pathomechanism contributing to myopathies.

54 d loci with disease and to shed light on the pathomechanisms contributing to FTD.

55 e regulation has made it possible to unravel pathomechanisms, enabling the design of new therapeutic

56 cal thinning constitutes a relevant cortical pathomechanism for altered cognitive activation in schiz

57 ansion, and malapposition comprises the main pathomechanism for both early and late BVS thrombosis, s

58 ting pore current have been established as a pathomechanism for hypokalaemic periodic paralysis.

59 eta-induced apoptosis in podocytes and a new pathomechanism for podocyte depletion in progressive glo

60 The pathomechanism for pycnodysostosis has been largely unkn

61 The pathomechanism for the myotonic dystrophies is not well

62 Although the underlying pathomechanisms for differential GA progression remain u

63 By understanding distinct pathomechanisms, for example, the role of IL-1, novel en

64 t of segmental aortic stiffening as an early pathomechanism generating aortic wall stress and trigger

65 A new pathomechanism has recently been identified in a group o

66 The underlying pathomechanisms have not been fully understood and we re

67 3-sulfate (CSO(4)) in the epidermis but the pathomechanism how elevated epidermal CSO(4) causes icht

68 The pathomechanisms, however, are poorly understood.

69 ted podocyte phenotype and suggests a common pathomechanism in collapsing FSGS, whether idiopathic or

70 Endothelial dysfunction is a central pathomechanism in diabetes-associated complications.

71 rotein interactions, and represents a common pathomechanism in HCM.

72 The key pathomechanism in humans with persistent speech comprehe

73 lar ion and fluid secretion may constitute a pathomechanism in lung edema and aimed to identify under

74 of microRNA target sites might be a relevant pathomechanism in Mendelian disorders.

75 -beta-induced podocyte apoptosis is an early pathomechanism in mice developing focal-segmental glomer

76 together, our results provide a novel common pathomechanism in multiple polyglutamine diseases that i

77 tosis of lung epithelial cells is a relevant pathomechanism in the development of hemorrhage-induced

78 lasts, further supporting a loss-of-function pathomechanism in this disease.

79 ans, and suggest a possible gene-environment pathomechanism in this disease.

80 d approach furthers the understanding of the pathomechanisms in ADHD and may advance treatment strate

81 ildren with AD and to investigate underlying pathomechanisms in atopic skin.

82 VB) and to characterize the mutation-related pathomechanisms in familial SND+AVB.

83 the potential of ECV to differentiate among pathomechanisms in HFpEF.

84 ality and balance, suggesting convergence of pathomechanisms in microsatellite expansion disorders an

85 ification has furthered the understanding of pathomechanisms in steroid-resistant nephrotic syndrome

86 Its etiology and pathomechanism is largely unknown, but misrouting of the

87 with a pronounced seasonal pattern, but the pathomechanism is not understood.

88 Among the proposed pathomechanisms is coronary vasospasm.

89 A more complete understanding of underlying pathomechanisms is leading to new treatments, which will

90 It is unclear whether similar or different pathomechanisms lead to these distinct clinical presenta

91 To elucidate the pathomechanism leading to obstructive vascular disease i

92 ly and provide a basis for understanding the pathomechanisms leading from mutations in the COL7A1 gen

93 A deeper understanding of the pathomechanisms leading to stress-related psychiatric di

94 A synopsis of pathomechanisms, novel differential diagnoses, and advan

95 lammatory signaling pathways involved in the pathomechanism of ALD.

96 great interest in further understanding the pathomechanism of ASPD.

97 interaction is an essential component of the pathomechanism of bipolar disorder.

98 The pathomechanism of bronchiolitis obliterans remains uncle

99 The role of the venous environment in the pathomechanism of CCMs remains unclear.

100 phrotic syndrome, and ROS formation may be a pathomechanism of COQ2-nephropathy.

101 ggest involvement of Th17 lymphocytes in the pathomechanism of disc degeneration.

102 The pathomechanism of DM1 is driven by accumulation of toxic

103 apse maturation represent a likely molecular pathomechanism of epilepsy and mental retardation in hum

104 US in cultured cells, and their roles in the pathomechanism of fALS remain obscure.

105 lying genetic lesion, offer insight into the pathomechanism of FCD.

106 yperexcitability of GABAergic neurons as the pathomechanism of FHM type 3.

107 et of pathogenic mutations is an alternative pathomechanism of FUS-related fALS diseases.

108 mannose-binding lectin-lectin pathway in the pathomechanism of HAE-C1-INH.

109 nt stimulatory effects on fibroblasts as the pathomechanism of hedgehog signaling in cGVHD.

110 suggests a role for activated T cells in the pathomechanism of liver damage.

111 f FLUX-reacting cytotoxic lymphocytes in the pathomechanism of liver injury and to dissect the involv

112 d a role for cytotoxic CD8(+) T cells in the pathomechanism of liver injury caused by FLUX.

113 Although the pathomechanism of NTG is still unknown, previous studies

114 ch is potentially valuable for understanding pathomechanism of PDM.

115 structural abnormalities are related to the pathomechanism of PDM.

116 Damage to podocytes is a central pathomechanism of proteinuric kidney disease.

117 A question has arisen regarding the pathomechanism of PXE, particularly the "metabolic" vers

118 A question has arisen regarding the pathomechanism of PXE, particularly the "metabolic" vers

119 thepsin K function provides insight into the pathomechanism of pycnodysostosis and may provide new dr

120 Moreover, to investigate the pathomechanism of RA by identifying correlations between

121 entifies cellular and matrix elements of the pathomechanism of SED.

122 fected by T. cruzi and provide a clue to the pathomechanism of sustained inflammation in Chagas disea

123 r acidic conditions might be relevant to the pathomechanism of the Asn-21 --> Ile mutation in heredit

124 P mutations failed to adequately explain the pathomechanism of the disease.

125 is a valuable resource in understanding the pathomechanism of the disease.

126 o C1-INH deficiency to better understand the pathomechanism of the evolution, course, and complete re

127 The pathomechanism of the mineralization is still obscure.

128 opathy in A/J(dys-/-) and BLAJ mice, but the pathomechanism of the myopathy is not understood.

129 gic children will outgrow their allergy, the pathomechanism of the natural development of tolerance r

130 Whereas the pathomechanism of the secondary mitochondrial dysfunctio

131 ect in mitochondrial translation defines the pathomechanism of their clinical disease.

132 epilepsy with centrotemporal spikes, and the pathomechanism of these epilepsies may be based on haplo

133 To investigate the pathomechanism of this disease, we generated and phenoty

134 nce to a systemic involvement of H2O2 in the pathomechanism of vitiligo.

135 similarities and differences of two distinct pathomechanisms of arterial calcifications: intimal asso

136 h CD, monitoring treatment, and studying the pathomechanisms of CD and development of preventive and

137 that may lead to better understanding of the pathomechanisms of chronic GvHD.

138 provide a new model with which to study the pathomechanisms of CKD.

139 g these processes is crucial for elucidating pathomechanisms of connective tissue disorders character

140 insight into specific uremia- and PD-induced pathomechanisms of CVD.

141 f the signalling pathways at the NMJ and the pathomechanisms of DOK7 CMSs.

142 eveloped to advance our understanding of the pathomechanisms of genodermatoses.

143 d to greater understanding of the underlying pathomechanisms of giant cell arteritis.

144 erplay between these proteins is part of the pathomechanisms of MLC.

145 However, relevant pathomechanisms of nephrotic syndrome have not been stud

146 s functions in mammals and help to elucidate pathomechanisms of neurological abnormalities in muscula

147 framework to consolidate seemingly distinct pathomechanisms of progression of glomerular and tubuloi

148 derived free radicals play a central role in pathomechanisms of reperfusion injury after organ transp

149 Here, we investigate pathomechanisms of sensory hair cell death and suggest a

150 nding mouse models, provide insight into the pathomechanisms of soft tissue mineralization and point

151 erstanding neural mechanisms involved in the pathomechanisms of specific affective disorders.

152 ncer and address the clinical phenotypes and pathomechanisms of specific neurotoxic chemotherapeutic

153 ported and have been implicated as potential pathomechanisms of Sudden Unexpected Death in Epilepsy (

154 aggerated CD4(+)Tem response fits within the pathomechanisms of T1D and how the effector memory can b

155 Currently, the cellular and molecular pathomechanisms of the DES mutations leading to this dis

156 factors that make uncovering of the precise pathomechanisms of these acquired disorders exceedingly

157 This model will help further discover the pathomechanisms of this devastating disease.

158 is caused by mutated TIA1 through a dominant pathomechanism probably involving altered stress granule

159 osphate, and the findings suggest a unifying pathomechanism relating to reduced inorganic pyrophospha

160 nt is not available, and many details of the pathomechanism remain unclear.

161 levance for outcome and survival, underlying pathomechanisms remain inadequately understood.

162 Here, we analyzed the pathomechanisms responsible for growth alterations in tr

163 The pathomechanism(s) by which mutant Cx26 hemichannels pert

164 sosomal homeostasis, illuminates a potential pathomechanism that is relevant to the role of AP-5 in n

165 H reveals novel insights into the integrated pathomechanisms that distinguish pathological versus phy

166 diseases has increased our understanding of pathomechanisms that is relevant to common neurological

167 ation have been proposed as putative primary pathomechanisms that may underlie progression of renal d

168 characterized by complex genetic traits and pathomechanisms that translate into clinical heterogenei

169 olled investigation exploring the underlying pathomechanisms through the assessment of disease onset

170 cascade that is essential for the underlying pathomechanism, thus expanding the list of potential fut

171 ntial for hemostasis, but it is also a major pathomechanism underlying ischemic injury.

172 ylation has become a focus of attention as a pathomechanism underlying severe congenital muscular dys

173 odels in this study can be used to elucidate pathomechanisms underlying chemotherapy-induced polyneur

174 However, pathomechanisms underlying EFE formation are still scarc

175 ibuted to our understanding of the molecular pathomechanisms underlying muscle degeneration.

176 of genetic modifiers to unravel the cellular pathomechanisms underlying SMA and the power of combinat

177 The pathomechanisms underlying the development of cutaneous

178 The pathomechanisms underlying very late stent thrombosis (V

179 To further elucidate pathomechanisms, we examined whether heart-specific Dsg2

180 Expression of markers relevant for these pathomechanisms were analysed in biopsies of sIBM, polym

181 al occlusion by aggregated NETs emerges as a pathomechanism with relevance in a plethora of inflammat

182 r allogeneic antigens; however, they share a pathomechanism with the activation of cytotoxic T lympho