ライフサイエンスコーパス: phosphatidate phosphatase

1 degradation was conserved for human lipin 1 phosphatidate phosphatase.

2 This was accompanied by a reduction in phosphatidate phosphatase 1 (PAP1) activity.

3 Saccharomyces cerevisiae membrane-associated phosphatidate phosphatase (3-sn-phosphatidate phosphohyd

4 was performed to determine the mechanism of phosphatidate phosphatase activation by anionic phosphol

5 biosynthesis of triacylglycerol through its phosphatidate phosphatase activity and also acts as a tr

6 positively charged sphingoid base, inhibited phosphatidate phosphatase activity and antagonized the a

7 Lipin proteins have phosphatidate phosphatase activity and catalyze the form

8 genase-like domains of Pah1 are required for phosphatidate phosphatase activity and the in vivo funct

9 ese results suggested that the activation of phosphatidate phosphatase activity by anionic phospholip

10 growth phase-mediated inductions of PAH1 and phosphatidate phosphatase activity do not correlate with

11 also abrogates the nuclear translocation and phosphatidate phosphatase activity of lipin-1.

12 Anionic phospholipids activated phosphatidate phosphatase activity whereas zwitterionic

13 se A, which cause a significant reduction in phosphatidate phosphatase activity, the phosphorylation

14 tase resulted in the stimulation (6-fold) of phosphatidate phosphatase activity.

15 f Pah1 regulate its subcellular location and phosphatidate phosphatase activity.

16 ane expansion, which occurs in cells lacking phosphatidate phosphatase activity.

17 nositol were mixed competitive activators of phosphatidate phosphatase activity.

18 Loss of phosphatidate phosphatase also resulted in the derepress

19 mation of diacylglycerol by the PAH1-encoded phosphatidate phosphatase and by channeling diacylglycer

20 PAH1-encoded phosphatidate phosphatase catalyzes the penultimate step

21 his enzyme, in conjunction with PAH1-encoded phosphatidate phosphatase, controls the levels of phosph

22 neither a substrate nor an inhibitor of pure phosphatidate phosphatase from S. cerevisiae.

23 Lipin-1 is a phosphatidate phosphatase in glycerolipid biosynthesis a

24 Pah1 phosphatidate phosphatase in Saccharomyces cerevisiae ca

25 Pah1 is the phosphatidate phosphatase in the yeast Saccharomyces cer

26 Yeast PAH1-encoded phosphatidate phosphatase is the enzyme responsible for

27 al loss-of-function mutation in the gene for phosphatidate phosphatase Lpin1 and a truncation mutatio

28 The dependence of phosphatidate phosphatase on phosphatidate was cooperati

29 reviously that the activity of the conserved phosphatidate phosphatase Pah1p/Smp2p regulates nuclear

30 Phosphatidate phosphatase (PAP) catalyzes the dephosphor

31 The Saccharomyces cerevisiae PAH1-encoded phosphatidate phosphatase (PAP) catalyzes the penultimat

32 Lipin-1 functions as a phosphatidate phosphatase (PAP) enzyme in the glycerol 3

33 The three lipin phosphatidate phosphatase (PAP) enzymes catalyze a step

34 The family of three lipin proteins act as phosphatidate phosphatase (PAP) enzymes required for gly

35 re evolutionarily conserved Mg(2+)-dependent phosphatidate phosphatase (PAP) enzymes with essential r

36 -1, lipin-2, and lipin-3) are Mg2+-dependent phosphatidate phosphatase (PAP) enzymes, which catalyze

37 Pah1p, which functions as phosphatidate phosphatase (PAP) in the yeast Saccharomyc

38 Early work indicates a role of the phosphatidate phosphatase (PAP) in this metabolism; the

39 Phosphatidate phosphatase (PAP) plays diverse roles in l

40 Yeast App1p is a phosphatidate phosphatase (PAP) that associates with end

41 The PAH1-encoded phosphatidate phosphatase (PAP), which catalyzes the com

42 myces cerevisiae PAH1-encoded Mg2+-dependent phosphatidate phosphatase (PAP1, 3-sn-phosphatidate phos

43 This result confirmed the role phosphatidate phosphatase plays in phosphatidylcholine s

44 doplasmic reticulum membrane to catalyze the phosphatidate phosphatase reaction.

45 Yeast Pah1p is the phosphatidate phosphatase that catalyzes the penultimate

46 Lipins are phosphatidate phosphatases that generate diacylglycerol

47 Lipins are evolutionarily conserved phosphatidate phosphatases that perform key functions in

48 ingle lipin homolog in yeast, Smp2, exhibits phosphatidate phosphatase type-1 (PAP1) activity, which

49 e showed that the expression of PAH1-encoded phosphatidate phosphatase was induced by zinc deficiency

50 including phosphatidylinositol synthase and phosphatidate phosphatase, were not affected in the cki1

51 Saccharomyces cerevisiae Pah1 phosphatidate phosphatase, which catalyzes the conversio

52 PAH1-encoded phosphatidate phosphatase, which catalyzes the dephospho

53 In Saccharomyces cerevisiae, Pah1 phosphatidate phosphatase, which catalyzes the dephospho

54 The yeast Pah1p phosphatidate phosphatase, which catalyzes the penultima