ライフサイエンスコーパス: phosphocholine

1 and POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine).

2 ol (e.g., glutathione, acetate, betaine, and phosphocholine).

3 olipid 1-palmitoyl-2-arachidonoyl-sn-glycero-phosphocholine.

4 lar vesicles of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine.

5 lower concentrations of choline, betaine and phosphocholine.

6 zed a new CRP mutant incapable of binding to phosphocholine.

7 d because of an increase of free choline and phosphocholine.

8 esicles (LUVs) of 1,2-dilauroyl-sn-glycero-3-phosphocholine.

9 osphodimethylethanolamine (pDME) and pDME to phosphocholine.

10 hydrolysis of CDP-choline to produce CMP and phosphocholine.

11 ysteine, methionine, and choline, as well as phosphocholines.

12 embly of stable 1,2-diphytanoyl-sn-glycero-3-phosphocholine 1,2-diphytanoyl-sn-glycero-3-phosphocholi

13 hospholipid [1,2-dihexadecanoyl-sn-glycero-3-phosphocholine, 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'

14 d of POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosph

15 into DMPC/DHPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine/1,2-dihexanoyl-sn-glycero-3-phosphoc holi

16 D-reconstituted 1,2-dimyristoyl-sn-glycero-3-phosphocholine/1,2-dimyristoyl-sn-glycero-3-phospho- (1'

17 nsisting of 1:1 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycero-3-phosphochol ine

18 n GUVs composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine/1,2-palmitoyl-sn-glycero-3-phosphocholin

19 coli in mixed 1,2-diheptanoyl-sn-glycerol-3-phosphocholine/1-myristoyl-2-hydroxy-sn-glycero-3-p hosp

20 y hydrated 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/1-palmitoyl-2-oleoyl-sn-glycero- 3-phosph

21 s, 14 amino acids, 9 lysophosphocholines, 72 phosphocholines, 10 sphingomyelins and sum of hexoses) a

22 the tear lipocalin-bearing fractions showed phosphocholines (104 ng/mL).

23 spholipid 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-PC), previously proposed to re

24 sphocholine, (iii) 1,2-dioleoyl-sn-glycero-3-phosphocholine/30 mol% cholesterol, (iv) 1,2-dierucoyl-s

25 ocholine, and (v) 1,2-dierucoyl-sn-glycero-3-phosphocholine/30 mol% cholesterol.

26 p methylation of phosphoethanolamine to form phosphocholine, a critical step in the synthesis of phos

27 rs prepared using 1,2-dilauroyl-sn-glycero-3-phosphocholine, a lipid with 12 carbon acyl chains, yiel

28 structure of human alk-SMase in complex with phosphocholine, a reaction product.

29 excitations in 1,2-dipalmitoyl-sn-glycero-3-phosphocholine above and below the main transition tempe

30 s successively to their substrate to produce phosphocholine, an important precursor for phospholipid

31 mimics of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine and 1,2-dipalmitoyl-sn-glycero-3-phosphoc

32 oxy-3-methoxy) cinnamoyl-2-acyl-sn-glycero-3-phosphocholine and 1-(4-hydroxy-3,5-dimethoxy) cinnamoyl

33 se) converts the lipid sphingomyelin (SM) to phosphocholine and ceramide and has optimum activity at

34 nts than into standard liposomes composed of phosphocholine and cholesterol using passive incubation.

35 ASD pup livers, with lower concentrations of phosphocholine and glycerophosphocholine in liver and hi

36 cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine and incorporating Na3[1-(2'-B10H9)-2-NH3B

37 We demonstrated previously that phosphocholine and phosphocholine-modified macromolecule

38 as saturated and polyunsaturated lipids with phosphocholine and phosphoethanolamine headgroups.

39 ratios of DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) and POPC (1-palmitoyl-2-oleoyl-sn-glycer

40 cholesterol, (iv) 1,2-dierucoyl-sn-glycero-3-phosphocholine, and (v) 1,2-dierucoyl-sn-glycero-3-phosp

41 umor xenograft mouse model, suppressed tumor phosphocholine, and diminished activating phosphorylatio

42 ch as 1-palmitoyl-2-oxovaleroyl-sn-glycero-3-phosphocholine, and of various lysophosphatidylcholines

43 tion in a natural antibody, B-1 responses to phosphocholine, and selective T-dependent impairment of

44 -Ficoll, production of natural antibodies to phosphocholine, and survival after intranasal pneumococc

45 [1-palmitoyl-2-(5-oxo-valeroyl)-sn-glycero-3-phosphocholine], and 1-palmitoyl-2-glutaroyl-sn-glycero-

46 functionality of polyclonal human IgG to the phosphocholine antigen was determined and showed that Ig

47 , and two zinc ions and one reaction product phosphocholine are identified in a histidine-rich active

48 n) in water with 1,2-dihexanoyl-sn-glycero-3-phosphocholine as detergent.

49 r analog CLR1404, 18-(p-iodophenyl)octadecyl phosphocholine, as a scaffold for tumor-targeted radioth

50 ating samples of 1,2-distearoyl-sn-glycero-3-phosphocholine at 60 degrees C for 24-72 h yielded an in

51 to that found in tears, we did not identify phosphocholines between m/z 490 and 540 in any of the ge

52 in (alm) pore in a 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayer at 313 K indicates that approxima

53 y hydrated 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayer environment.

54 compound through a 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayer is determined by molecular dynami

55 d show that in the 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayer, charged residues of the protein

56 versely, in the 1,2-dimyristoyl-sn-glycero-3-phosphocholine bilayer, the overall hydrophobic-hydrophi

57 ions results on the interaction of NaCl with phosphocholine bilayers have to be reconsidered and revi

58 f GA dimers from 1,2-distearoyl-sn-glycero-3-phosphocholine bilayers were significantly different for

59 c membranes and 1,2-dimyristoyl-sn-glycero-3-phosphocholine bilayers, whereas M2(22-46) has minimal e

60 into suspended 1,2-diphytanoyl-sn-glycero-3-phosphocholine bilayers, while simultaneously recording

61 supported DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) bilayers, deposited via the Langmuir-Blo

62 al divergence leading to the alteration of a phosphocholine binding pocket found in the staphylococca

63 were reversible at pH 7.0, for example, the phosphocholine-binding activity of CRP, which was reduce

64 We conclude that the phosphocholine-binding pocket on CRP is necessary for CR

65 hat Phe(66), Thr(76), and Glu(81) formed the phosphocholine-binding pocket, we constructed a CRP muta

66 ne-3-pentanoyl)-1-hexadec anoyl-sn-glycero-3-phosphocholine (BODIPY C(5)-HPC), and an organic salt, 1

67 Mutant CRP did not bind to phosphocholine, C-polysaccharide, or pneumococci.

68 es only the lipid class via formation of the phosphocholine cation.

69 Based on the structure of CRP-phosphocholine complexes, which showed that Phe(66), Thr

70 increased breast-milk choline, betaine, and phosphocholine concentrations and increased plasma choli

71 ange flux, the alkaline Pi-pool, and glycero-phosphocholine concentrations between the groups.

72 Because CRP binds to phosphocholine-containing substances and subsequently ac

73 line (DPPC) and 1,2-dilinoleoyl-sn-glycero-3-phosphocholine [corrected].

74 CTP:phosphocholine cytidylyltransferase (CCT) interconverts

75 CTP:phosphocholine cytidylyltransferase (CCT), an amphitropi

76 C synthesis, PEMT and cytidine triphosphate: phosphocholine cytidylyltransferase (PCT), S-adenosylmet

77 conserved prokaryotic choline kinase and CTP:phosphocholine cytidylyltransferase activities with a 1,

78 he CDP-choline pathway for PC synthesis, CTP:phosphocholine cytidylyltransferase alpha (CCTalpha) is

79 The reversible association of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha) wit

80 mTORC1 promoted TAG secretion by regulating phosphocholine cytidylyltransferase alpha (CCTalpha), th

81 N-methyltransferase and hepatic-specific CTP:phosphocholine cytidylyltransferase alpha.

82 way for PC biosynthesis was catalyzed by CTP:phosphocholine cytidylyltransferase.

83 pah1 pah2 is suppressed by disruption of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE1 (CCT1), which encod

84 line (DC22:1PC) or 1,2-dioleoyl-sn-glycero-3-phosphocholine (DC18:1PC) lipid vesicles using a fluores

85 nge of gA between 1,2-dierucoyl-sn-glycero-3-phosphocholine (DC22:1PC) or 1,2-dioleoyl-sn-glycero-3-p

86 e were identified in the presence of dodecyl phosphocholine detergent micelles.

87 th rhodopsin in 1,2-diheptanoyl-sn-glycero-3-phosphocholine (DHPC) micelles is investigated by soluti

88 oline (DMPC) and 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC) self-assemble to form thermo-respo

89 oline (DMPC) and 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC), with [DMPC]/[DHPC] = 2.5, in 10%

90 In 1,2-dilauroyl-sn-glycero-3-phosphocholine (diC(12:0)PC) liposomes, the post-adsorpt

91 multibilayers of 1,2-dilauroyl-sn-glycero-3-phosphocholine (dilauroylphosphatidylcholine, DLPC) are

92 n the phospholipids dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and 1,2-dihexanoyl-sn-glycero-3-ph

93 preparation of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and 1,2-dihexanoyl-sn-glycero-3-ph

94 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and its mixtures with different am

95 uid crystalline 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and POPC/POPS 3:1 liposomes retain

96 tterionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) are investigated as constructs for

97 showed that in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) bilayers, the first equivalent of

98 ing kinetics in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes, suggesting that lateral

99 phospholipids (1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phos

100 gle bilayers of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)/1,2-dipalmitoyl-sn-glycero-3-phosp

101 ine (DPPC), and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC:DSPC).

102 man (liposomes of 1,2-dimyristoyl-sn-glycero-phosphocholine, DMPC) and the bacterial (liposomes of 1,

103 In stark contrast to choline, phosphocholine does not evoke ion current responses in X

104 composed of either 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) (fluid at room temperature) or 1,2

105 d lipid bilayer of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) containing 4 mol % biotinylated-ca

106 n efficiently bind 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) in nonpolar solvents.

107 TB) to a GM1-doped 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) lipid bilayer were investigated by

108 of an FDA-approved 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) lipid monomer.

109 scale, fluid-phase 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes contacting a titanium di

110 y of miR-630 using 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) nanoliposomes resulted in increase

111 cles membranes made of dioleoyl-sn-glycero-3-phosphocholine (DOPC) or 1-palmitoyl-2-oleoyl-sn-glycero

112 by spreading giant 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) vesicles on porous anodic aluminum

113 sed of zwitterionic 1,2-dioleoyl-sn-glyero-3-phosphocholine (DOPC), as well as DOPC vesicles, were us

114 ut not the control 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), binds directly to S6K and causes

115 ure SM/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), focusing on the importance of the

116 pids investigated, 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)-based proteoliposomes were found t

117 choline (POPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).

118 es in a bilayer of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).

119 holine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/1,2-dihexadecanoyl-sn-glycero-3-ph

120 lamellar vesicles [1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/1,2-dipalmitoyl-sn-glycero-3-phosp

121 ry lipid mixtures (1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC):DSPC, DOPC:1,2-dipalmitoyl-sn-glyc

122 -phosphocholine 1,2-diphytanoyl-sn-glycero-3-phosphocholine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-pho

123 temperature) or 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) (gel at room temperature) with a r

124 layer made from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1,2-dilinoleoyl-sn-glycero-3-p

125 ary mixtures of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and asialo-(GA1), disialo-(GD1b) a

126 cholesterol and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in the liquid-ordered (l(o)) and l

127 rtitioning into 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) lipid vesicles as a function of so

128 ffer, gel-phase 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) liposomes verified that the LSPR m

129 oline (DOPC)/1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) membranes.

130 having either a 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) or mixed-DPPC/cardiolipin membrane

131 ocholine (DMPC)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) phospholipid mixtures using quartz

132 omposed of pure 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) was measured and compared to trans

133 intensities of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dipalmitoyl-sn-glycero-3-phos

134 OPC):DSPC, DOPC:1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and 1,2-dimyristoyl-sn-glycero-3-

135 choline (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and 1-palmitoyl-2-oleoyl-sn-glyce

136 nd subsequently 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC).

137 rs derived from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC).

138 ocholine (DOPC)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)], we report a dramatic influence o

139 o phospholipids, 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-dipalmitoyl-sn-glycero-3-p

140 ted phospholipid 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), mixed with varying amounts of the

141 rically prepared 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC):1,2-distearoyl(d70)-sn-glycero-3-p

142 line (DSPC):1,2-distearoyl(d70)-sn-glycero-3-phosphocholine (DSPC-d(70)) lipid bilayer arrays.

143 palmitoyl-2-[(14)C]arachidonoyl-sn-glycero-3-phosphocholine during incubations with wild-type heart m

144 1-O-Alkyl-2-carboxymethyl-sn-glycero-3-phosphocholine (Edelfosine) like other short-chained pho

145 he structure we show that NetB does not bind phosphocholine efficiently but instead interacts directl

146 oline, 1-palmitoyl-2-azelaoyl-sn-glydecero-3-phosphocholine, efficiently opposes the miscibility tran

147 SM) hydrolyzes sphingomyelin to ceramide and phosphocholine, essential components of myelin in neuron

148 3,5-dimethoxy) cinnamoyl-2-acyl-sn-glycero-3-phosphocholine exhibited excellent antioxidant activity

149 -methoxy) cinnamoyl-2-palmitoyl-sn-glycero-3-phosphocholine exhibited good antibacterial activity aga

150 droxy-3-methoxy) benzoyl-2-acyl-sn-glycero-3-phosphocholine exhibited good antifungal activity agains

151 imethoxy) cinnamoyl-2-palmitoyl-sn-glycero-3-phosphocholine exhibited good antioxidant activity with

152 methylation of phosphoethanolamine (pEA) to phosphocholine for membrane biogenesis.

153 fPMT methylates phosphoethanolamine (pEA) to phosphocholine for use in membrane biogenesis.

154 Its production involves the transfer of phosphocholine from phosphatidylcholine onto ceramide, a

155 LA2 and ENPP6 may act in concert to generate phosphocholine from the matrix vesicle membrane during s

156 n of S-adenosylmethionine, betaine, choline, phosphocholine, glyceophosphocholine, cystathionine, cys

157 se mice had lower concentrations of choline, phosphocholine, glycerophosphocholine, phosphatidylcholi

158 ntified were choline, glycerophosphocholine, phosphocholine, glycine betaine, N-methylproline, prolin

159 Glycero-3-phosphocholine (GPC), the product of the complete deacyl

160 ng compounds (ie, glycerophosphocholine plus phosphocholine (GPC+PC)) in bipolar disorder using in vi

161 tosyl residues in glycosphingolipids and the phosphocholine group in phospholipids.

162 olysis of sphingomyelin (SM) to ceramide and phosphocholine, have been found in the mitochondria of y

163 ored the effects of reducing the size of the phosphocholine headgroup (removing one, two, or three me

164 se results indicate that PC acyl editing and phosphocholine headgroup exchange between PC and diacylg

165 ith an HC surfactant carrying a zwitterionic phosphocholine headgroup gives rise to two coexisting mi

166 , accommodation of ceramide under the larger phosphocholine headgroup of SM could contribute to their

167 h as m/z 184, which is characteristic of the phosphocholine headgroup, were then used to confirm the

168 A small-molecule inhibitor of pCRP (1,6-bis(phosphocholine)-hexane), which blocks the pCRP-microvesi

169 tic target, we stabilized pCRP using 1,6-bis(phosphocholine)-hexane, which prevented dissociation in

170 Preincubation of these oocytes with phosphocholine, however, attenuated choline-induced ion

171 -cell mimic), (ii) 1,2-dioleoyl-sn-glycero-3-phosphocholine, (iii) 1,2-dioleoyl-sn-glycero-3-phosphoc

172 The major metabolites of 11C-choline were phosphocholine in HCC and betaine and choline in the sur

173 sphocholine and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine in the liquid-ordered (lo) and liquid-dis

174 y, reduced the steady-state concentration of phosphocholine in transformed cells, and selectively sup

175 ation with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, in bilayers with equal acyl chain order.

176 1-palmitoyl-2-(5'-oxovaleroyl)-sn-glycero-3-phosphocholine, in the lungs.

177 cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine, incorporating K[nido-7-CH3(CH2)15-7,8-C2

178 A structure in complex with phosphocholine indicates that the protein recognizes thi

179 mpounds exhibit a dose-dependent decrease of phosphocholine, inhibition of cell growth, and induction

180 In this study, we demonstrate that phosphocholine inhibits ion-channel function of ATP rece

181 ol% alpha-tocopherol in 1-palmitoyl-2-oleoyl-phosphocholine inhibits leakage of phenol red dye from l

182 Zwitterionic inverse-phosphocholine (iPC) lipids contain headgroups with an i

183 es, the low binding affinity between CRP and phosphocholine is exploited in a "low-sensitive" sandwic

184 many cancers, and the product of the enzyme, phosphocholine, is also increased in tumor cells.

185 factor (PAF [1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine]) is a phospholipid mediator released fro

186 ant lipid-related alterations were increased phosphocholine levels (increased 70% in endometrial canc

187 atment with the Akt inhibitor MK2206 reduced phosphocholine levels in MDA-MB-468 cells.

188 In a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine lipid bilayer and a plasma membrane envir

189 w, using supported 1,2-dioleoyl-sn-glycero-3-phosphocholine lipid bilayers in different saline soluti

190 serts into 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine lipid bilayers with an apparent pK(a) of

191 in was dispersed in diphytanoyl-sn-glycero-3-phosphocholine lipid bilayers, and the spectra and an ex

192 er carbonyl stretching vibration in hydrated phosphocholine lipid bilayers, we are able to measure a

193 erted into 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine lipid nanodiscs and the kinetics of activ

194 In this study, inverse phosphocholine lipids (CP) are used, directly exposing t

195 el membranes of 1,2-dimyristoyl-sn-glycero-3-phosphocholine lipids at pH > pHagg, we found that membr

196 article was to identify by mass spectrometry phosphocholine lipids in stimulated human tears and dete

197 onstituted into 1,2-dimyristoyl-sn-glycero-3-phosphocholine liposomes by (31)P MAS NMR.

198 hilic regions of 1,2-distearoyl-sn-glycero-3-phosphocholine liposomes.

199 ry with the aid of 1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes.

200 rionic diC12:0PC (1,2-dilauroyl-sn-glycero-3-phosphocholine) liposomes and negatively charged 80:20 d

201 ic) than in 1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine (LLPC, zwitterionic) micelles.

202 induced ion current changes, suggesting that phosphocholine may act as a silent agonist.

203 n an all-atom DOPC (1,2-dioleoylsn-glycero-3-phosphocholine) membrane-water environment.

204 -supported 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine membranes doped with different phosphoino

205 c membranes but mostly beta-sheet in neutral phosphocholine membranes.

206 tion structure of huntingtin 1-17 in dodecyl phosphocholine micelles and the topology of its helical

207 Rp were conducted in the presence of dodecyl phosphocholine micelles to solvate the membrane anchor o

208 protein hemagglutinin HA2, bound to dodecyl phosphocholine micelles, was recently shown to adopt a s

209 that acetylcholine, choline, phosphocholine, phosphocholine-modified LPS from Haemophilus influenzae,

210 onstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhib

211 Of note, we identify receptors for phosphocholine-modified macromolecules that are synthesi

212 odified LPS from Haemophilus influenzae, and phosphocholine-modified protein efficiently inhibit ATP-

213 nction of CRP requires the binding of CRP to phosphocholine moieties present in pneumococcal cell wal

214 ogical pH, is for substances bearing exposed phosphocholine moieties.

215 rectly mediates the covalent attachment of a phosphocholine moiety to Rab1.

216 aviour of DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) multilamellar vesicles.

217 inds to zwitterionic detergents that contain phosphocholine or phosphatidylcholine head groups and ph

218 ized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine [Ox-PAPC]) and proinflammatory cytokines

219 ized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (OxPAPC) and its derivatives were identif

220 ized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine [OxPAPC]) promote endothelial cell (EC) b

221 s of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC) oxidation that contain cyclopenthe

222 C isomers, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (PC(16:0/18:1)) and 1-oleoyl-2-palmitoyl-

223 18:1)) and 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine (PC(18:1/16:0)), were subjected to this i

224 oncentration- and time-dependent decrease in phosphocholine (PC) and total choline (tCho) levels (P <

225 phore featuring spatially separated urea and phosphocholine (PC) groups forms a macrocyclic "head-to-

226 The HDAC inhibitors LAQ824 and SAHA increase phosphocholine (PC) levels in human colon cancer cells a

227 Zwitterionic phosphocholine (PC) lipids are highly biocompatible, rep

228 h an inverted charge orientation relative to phosphocholine (PC) lipids.

229 line-binding domain that anchors PspA to the phosphocholine (PC) moieties on the pneumococcal surface

230 s from Lip to yield diacylglycerol (DAG) and phosphocholine (PC) products, leading to the decompositi

231 , a decreased glycerophosphocholine (GPC) to phosphocholine (PC) ratio was reported in breast, ovaria

232 rolysis of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (PC), a zwitterionic lipid.

233 sicle were made with varying compositions of phosphocholine (PC), phosphoethanolamine (PE), cholester

234 naling pathway and resulted in a decrease in phosphocholine (PC), total choline (tCho) and lactate le

235 Phosphocholine (PC)-containing OxPL (OxPC) present on pl

236 d as 1-hexadecyl-2-octadecenoyl-sn-glycero-3-phosphocholine [PC(16:0e/18:1)] using tandem mass spectr

237 nds to cells and molecules that have exposed phosphocholine (PCh) groups.

238 The involvement of the phosphocholine (PCh)-binding property of CRP in its anti

239 Phosphocholine (pCho) is a precursor for phosphatidylcho

240 oyl-2-(5,6-epoxyisoprostane E2)-sn-glycero-3-phosphocholine, PEIPC, a proinflammatory molecule that a

241 PC) and 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine (PGPC), are two major oxidation products

242 rticle, we show that acetylcholine, choline, phosphocholine, phosphocholine-modified LPS from Haemoph

243 anionic (phosphoinositol) and zwitterionic (phosphocholine, phosphoethanolamine) head groups, doubly

244 ng to produce Pi PHOSPHO1 is a dual-specific phosphocholine/phosphoethanolamine phosphatase enriched

245 y the transfer of the phosphoethanolamine or phosphocholine polar head group, respectively, to the di

246 1-palmitoyl-2-(9'-oxononanoyl)-sn-glycero-3-phosphocholine (PONPC), is of major interest as they pla

247 spholipids 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dioleoyl-sn-glycero-3-phos

248 omposed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-palmitoyl-2-oleoyl-sn-glycer

249 tration of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and pressure (Pi) before adsorptio

250 trix lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and the MI-MII equilibrium measure

251 spholipid, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) incorporating two molecules of apo

252 (HAs) with 1-palmitoyl-2-oleoyl-Sn-glycero-3-phosphocholine (POPC) large unilamellar vesicle (LUV) mo

253 nd neutral 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) liposomes.

254 ly bind to 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes, whereas Cl(-) ions stay

255 ructure of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes.

256 ospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) the two-state model was found to b

257 DPPC), and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)), and the average GM1 and choleste

258 (DOPC) or 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), by irradiating methylene blue pre

259 onic lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), the negatively charged 1-palmitoy

260 the ApoA1-1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)-based particles are disk shaped wi

261 osition of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)-containing PDs at neutral pH diffe

262 dylserine (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)/1-palmitoyl-2-oleoyl-sn-glycero-3-

263 1-palmitoyl-2-(5'-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) and 1-palmitoyl-2-(9'-oxononanoyl

264 , 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) and 1-palmitoyl-2-glutaroyl-sn-gl

265 f 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) or 1-palmitoyl-2-glutaroyl-sn-gly

266 ermine that SMase and its enzymatic product, phosphocholine, prevent Th2-mediated increases in alpha

267 on structures of PfPMT with pEA (substrate), phosphocholine (product), sinefungin (inhibitor), and bo

268 c tissues at 12 min after injection; in HCC, phosphocholine rapidly converted to phosphatidylcholine

269 CD36 in reducing inflammation induced by the phosphocholine residues of pneumococcal lipoteichoic aci

270 A modifications with D-alanyl, glycosyl, and phosphocholine residues will be discussed along with the

271 te that S. pneumoniae binds to cells via its phosphocholine residues, and suggest a role for CD36 in

272 ith S-adenosylhomocysteine and either pEA or phosphocholine reveal how mutation of Asp-128 disrupts a

273 e of PsaA in complex with both galactose and phosphocholine reveals separate receptor binding sites t

274 The product of choline kinase-alpha, phosphocholine, serves as an essential metabolic reservo

275 ry lipid mixtures (1,2-dioleoyl-sn-glycero-3-phosphocholine/sphingomyelin/cholesterol) into liquid-di

276 We used phosphocholine spin labels on the lipid headgroup and di

277 trations of the alkaline Pi-pool and glycero-phosphocholine, suggesting the possibility of using high

278 d 18:0) on 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine-supported lipid bilayers.

279 However, when bound to a phosphocholine surface Nogo-66 adopts a unique, stable f

280 ethanolamine, glucose, lactate, myoinositol, phosphocholine, sylloinositol, and valine showed statist

281 )ben zyl]oxy]carbonyl]nonanoyl]-sn-glycero-3-phosphocholine, the association of PMCA to actin produce

282 atch produced by a 1,2-dioleoyl-sn-glycero-3-phosphocholine thicker bilayer could be a structural fou

283 )ben zyl]oxy]carbonyl]nonanoyl]-sn-glycero-3-phosphocholine to the protein.

284 This phosphocholine transferase activity used CDP-choline as

285 VPC) or 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine, two oxidized phospholipids (oxPLs) that

286 nal channel domain that mediated glucose and phosphocholine uptake across the outer membrane in an M.

287 ate functional nanopores in DIBs composed of phosphocholine using the protein alpha-hemolysin (alphaH

288 a-barrel) and two different detergent types (phosphocholines versus an alkyl sugar) with respect to p

289 ipid domains in 1,2-dimyristoyl-sn-glycero-3-phosphocholine vesicles is observed to occur in as fast

290 maller than the 1,2-dimyristoyl-sn-glycero-3-phosphocholine vesicles.

291 gest that Caenorhabditis elegans synthesizes phosphocholine via two S-adenosylmethionine (AdoMet)-dep

292 In bicellar systems comprising 14-C phosphocholines, we observe that protein-lipid interacti

293 to the pneumococcal polysaccharide component phosphocholine were significantly lower in A181E-heteroz

294 Ten other monoisotopic phosphocholines were found in tears.

295 e], and 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine, were identified in the extracted lipid p

296 lipid in eukaryotic cells, into ceramide and phosphocholine, which are then utilized by Mtb as carbon

297 idylcholine found in MV membranes to produce phosphocholine, which PHOSPHO1 can hydrolyze to liberate

298 here are no other reports on interactions of phosphocholine with nAChR.

299 ontaining either a carbonate or zwitterionic phosphocholine within the polymer backbone.

300 ning POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine) yielded an equilibrium dissociation cons