1 one of three Cys and two Ser residues of the prepeptide.

2 st-translational modification of the mutacin prepeptide.

3 tional modification during maturation of the prepeptide.

4 cause they lack the first exon, encoding the prepeptide, and follow a translation stop in the C6.1A g

5  lividans of both the wild-type berninamycin prepeptide (BerA) and also a T3A mutant generates macroc

6                                 The complete prepeptide consists of 53 amino acids, including the 26

7 he enzyme, however, does cleave the released prepeptide from precitrate synthase.

8 ncing has revealed several other phosphatase-prepeptide gene pairs in B. subtilis, suggesting that th

9                           We have introduced prepeptide gene variants into a knockout strain to condu

10 verts the C-terminal 14 residues of a 52-mer prepeptide into a related set of eight variants of the t

11                                          The prepeptide is removed by a signal peptidase, and the pro

12 al of an N-terminal leader sequence from the prepeptide LctA and export of the mature lantibiotic.

13 acticin 481 is synthesized on ribosomes as a prepeptide (LctA) and posttranslationally modified to it

14             The gene encoding the mutacin II prepeptide, mutA, was subsequently cloned and sequenced.

15  The mRNA is predicted to be translated to a prepeptide of 138 amino acids in length and processed to

16 e producing microbes, the genes encoding the prepeptide open reading frames are flanked in biosynthet

17 translational modifications on 50-60-residue prepeptide precursors that trim away the N-terminal lead

18 ed in the dehydration and cyclization of the prepeptide, several putative transporter and regulatory

19                                          The prepeptide showed similarity to the lantibiotics lactici

20 ter maturation and secretion) proteins whose prepeptide substrates share a conserved double-glycine t

21 i permitted identification of a thiostrepton prepeptide, TsrA, and involvement of TsrA in thiostrepto