ライフサイエンスコーパス: protective effect

1 tion (0.01-2.5 g per day) and high BMI had a protective effect.

2 ograms might remove this helminth-associated protective effect.

3 ion of calcineurin, which likely confers the protective effect.

4 K increased autophagy and exhibited strongly protective effect.

5 exercise explained a small proportion of the protective effect.

6 wide CI that includes a clinically important protective effect.

7 etion of Tregs from the graft abrogated this protective effect.

8 during viral-induced encephalitis may have a protective effect.

9 as treatment with warfarin appears to have a protective effect.

10 Unexpectedly, FXII has a protective effect.

11 in the extract were identified to exert cyto-protective effect.

12 nd minerals in nuts may confer this observed protective effect.

13 found to be the mechanism underpinning this protective effect.

14 nate repair receptor; IRR), and exert tissue protective effects.

15 at Ape1 is indispensable for GAPDH-dependent protective effects.

16 nnosidase activity was dispensable for these protective effects.

17 unctional activation of the ETB receptor has protective effects.

18 n, as IFNgamma-deficient mice do not exhibit protective effects.

19 ts from different genotypes of acai showed a protective effect (13-62%) on SH-SY5Y cells insulted by

20 a circulation have demonstrated a consistent protective effect against a variety of adverse birth out

21 Topical use of B. lactis HN019 promotes a protective effect against alveolar bone loss and CTALs a

22 xon of ANK3 and has a strong and significant protective effect against bipolar disorder (odds ratio =

23 This protective effect against bone loss disappeared when onl

24 Physical activity has a protective effect against cardiovascular disease (CVD) i

25 diet-induced liver injury and abolished the protective effect against cholesterol lipotoxicity in So

26 tes by transgenic overexpression of sEH, the protective effect against CNV was lost.

27 s from CSC-treated uninfected cells showed a protective effect against cytotoxicity and viral replica

28 xposure was associated with a dose-dependent protective effect against death or neurodevelopmental im

29 insulin signaling and its deletion exerts a protective effect against diet-induced obesity.

30 otein hydrolysates (fraction <10kDa) exerted protective effect against free-radical induced cytotoxic

31 n of the extent to which the immune system's protective effect against one herpes simplex virus type

32 Puerariae Lobatae Radix (PLR) exerts cyto-protective effect against oxidative stress due to its hi

33 trate that the production of PGE2 provides a protective effect against the antiviral effector mechani

34 control mice, whereas control BM cells had a protective effect against the development of disease, wh

35 and demonstrated a statistically significant protective effect against the development of hospital ac

36 ed risk of incident MS, while SAT may have a protective effect against the incidence of individual MS

37 (HIF) beta in the VHL-deficient CC-RCC had a protective effect against Y-27632 treatment, mimicking V

38 all gaseous molecule that exhibits promising protective effects against a variety of physiological an

39 s in mice and humans suggested that GHRD has protective effects against age-related diseases, includi

40 Bacterial taxa with protective effects against development of CDI were ident

41 like macrophages in fibrotic liver exert the protective effects against lethal insults through confer

42 enz and Sephin1) have been proposed to exert protective effects against misfolding by interfering wit

43 tivity in APP mice; and that SS31 may confer protective effects against mitochondrial and synaptic to

44 ives which prolong food storage due to their protective effects against oxidative degradation of food

45 ants contained in these seasonings may exert protective effects against oxidative stress along the ga

46 city, was unexpectedly found to exert marked protective effects against photoreceptor degeneration.

47 ther proteasome inhibitors have similar bone-protective effects against radiation damage.

48 OxPAPC-induced EC barrier enhancement or the protective effects against thrombin-induced EC permeabil

49 ubsequent antitumour immunity also generated protective effects against tumour-cell populations that

50 Spore viability was measured for protective effect and bioassay test was performed on the

51 s a systemic miR-100 replacement therapy had protective effects and attenuated atherogenesis, resulti

52 the present study, we describe the potential protective effects and mechanisms of myricitrin (Myr) on

53 We aim to evaluate the protective effects and the possible mechanism of methazo

54 The protective effects are lost in CMA-deficient cells, sugg

55 uals without T2D, providing support that the protective effects are mediated by reductions in IGF2 is

56 tudies are required to determine if the same protective effects are observed in combination with othe

57 The protective effect associated with epigenetic mechanisms,

58 There was no additional protective effect associated with taking the highest dos

59 obial-derived Neu5Gc might contribute to the protective effects associated with the farm environment.

60 Here we demonstrate that this protective effect associates with decreased proliferatio

61 ponses in children and may have a clinically protective effect at the population level.

62 in early DN, miR-146a upregulation exerts a protective effect by downregulating target inflammation-

63 ced by LPS, whereas FruArg accounted for the protective effect by reversing expression levels of 55%

64 These data suggest that histamine exerts protective effects by modulating cardiac fibrosis and re

65 d from the iPSC-derived cardiomyocytes exert protective effects by transferring the endogenous molecu

66 We found that SAL mimicked NAP's protective effects, by preventing axonal transport disru

67 This protective effect correlated well with the substantial i

68 Surprisingly, this protective effect could also be induced by a nicotinic r

69 cell activation can abrogate any potentially protective effects delivered by vaccination or promote a

70 naling in IECs results in a number of tissue-protective effects during inflammation; however, a ratio

71 These results demonstrate the onset of protective effects earlier than previously determined, p

72 bits long-lasting anti-inflammatory and lung-protective effects even after single administration in v

73 antagonist increased mortality, indicating a protective effect for estrogen receptor signaling in mic

74 timated effect implied that AGTR1 may have a protective effect for hypertension.

75 of encephalitis and suggests that IL-1 has a protective effect for the development of MAV-1-induced e

76 A protective effect from death by the transfusion was foun

77 roteasomal degradation of Nrf2, has a strong protective effect in a preclinical model of cSCC.

78 ithout immunosuppression and established its protective effect in autoimmune diseases.

79 s, magnesium sulphate treatment had a strong protective effect in both the overall analysis (RR 0.68,

80 x1), an antioxidant enzyme, in flow-mediated protective effect in endothelial cells.

81 Octreotide exerts a protective effect in hepatic ischemia-reperfusion (HIR)

82 vatives were identified that possess greater protective effect in human induced pluripotent stem cell

83 extracts exerts an immune modulatory hepato-protective effect in NASH model.

84 However, we did not observe a similar protective effect in SIV-infected African monkeys coinfe

85 but not wild-type (WT) SMNDelta7, provides a protective effect in SMA model mice and human motor neur

86 n skeletal muscle of old mice or provide any protective effect in the context of muscle aging.

87 in homozygous individuals, whereas it has a protective effect in the heterozygous state.

88 atening diarrhea, and may even have a slight protective effect in this regard, but it is a major cont

89 s, such as docosahexaenoic acid, have tissue protective effects in acute inflammation.

90 IL-27 exerts protective effects in autoimmune diseases like experimen

91 ies show that PDE5 inhibitors (PDE5is) exert protective effects in DN improving perivascular inflamma

92 eloped to enable antiinflammatory and tissue protective effects in inflammatory pathologies of the gu

93 to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia

94 antidiabetic drug that exerts cardiovascular protective effects in patients with diabetes.

95 and clinical data have suggested their organ-protective effects in patients with ischemia and reperfu

96 r of fibrosis and is the first to show FAP's protective effects in the lung.

97 bility of neutralizing antibodies to mediate protective effects in vivo is undetermined.

98 lization for the ability of bnAbs to mediate protective effects in vivo, however, is undetermined.

99 These protective effects involved modulation of NF-kappaB acti

100 This protective effect is restricted to the molecular interac

101 ures at the basis of the R61T-ApoE4 mutant's protective effect is still missing.

102 Similar strong protective effects may be present in the immediate postp

103 Pale skin color showed a protective effect (men: -21.0%Delta; women: -28.5%Delta)

104 Helium and xenon show organ protective effects mostly in small animal ischemia reper

105 Furthermore, similar antiviral and protective effects occur by inducing the expression of h

106 The majority of this protective effect occurred at low levels of exercise and

107 SNP rs193053835 showed the most significant protective effect (Odds Ratio (OR) = 0.62, 95% confidenc

108 to steroid treatment shows a trend toward a protective effect (odds ratio, 0.16; 95% CI, 0.0-1.3; P

109 be associated with the disorder and for the protective effect of 22q11.2 duplication.

110 In confirmatory animal studies, the protective effect of [Nle(4), D-Phe(7)]-alpha-melanocyte

111 Demethylation of DNA abrogated the protective effect of AC whereas remethylation of AC DNA

112 is study adds to the limited evidence of the protective effect of adherence to a Mediterranean dietar

113 in any locus across the genome) indicated a protective effect of adiponectin that was attenuated to

114 ar endothelial growth factor strengthens the protective effect of amniotic fluid stem cells in a rena

115 ntal and epidemiological research suggests a protective effect of angiotensin II receptor blockers.

116 ging time was prolonged from 12 to 36 h, the protective effect of antioxidants became more obvious.

117 corroborated in renal IRI, where the tissue protective effect of aPC was likewise dependent on Nlrp3

118 y active Nlrp3(A350V) mutation abolished the protective effect of aPC, demonstrating that Nlrp3 suppr

119 We found a protective effect of ART initiation on mortality, as wel

120 ' collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye d

121 d systematic reviews show some evidence of a protective effect of breastfeeding against primary denti

122 dextrin or cholesterol oxidase abolished the protective effect of C4BP on IAPP cytotoxicity of INS-1

123 In a stratified analysis, the protective effect of CaD on fracture risk was observed i

124 These data demonstrate a protective effect of carbamylcholine on VFT that depends

125 In this report, we investigated the retina-protective effect of chrysophanol, an active component o

126 mization assumptions, our findings suggest a protective effect of CRP and a risk-increasing effect of

127 cking down COX2 expression did not alter the protective effect of DETA-NO on cell survival.

128 rable course in pCIS and POMS and supports a protective effect of early DMD treatment in preventing M

129 In contrast, the potentially positive protective effect of early influenza virus infection lat

130 Results showed a protective effect of EBOTAb given post-exposurally, with

131 This study assesses how the protective effect of education changes under IMF program

132 ant forms of EphB2, we demonstrate that this protective effect of EphB2 depends on its PDZ-binding mo

133 Notably, the protective effect of etifoxine was abolished in mice dep

134 Our results demonstrate the protective effect of exercise on neurovascular damage in

135 atic review and meta-analysis quantified the protective effect of facemasks and respirators against r

136 complement activation, which may explain the protective effect of FHR-1 deficiency in age-related mac

137 regnancy are sufficient to explain the known protective effect of full-term pregnancy in early adulth

138 ummary, our findings suggest a neurovascular protective effect of GHRH analogs during the early stage

139 Most of the immunologic assays confirmed a protective effect of H. pylori.

140 The protective effect of Hdac1 ablation was detected also in

141 Mechanistic studies in mice have linked the protective effect of helminths on autoimmunity to the su

142 No protective effect of higher-dose NOACs in preventing all

143 ovide a mechanistic basis for the dominantly protective effect of HLA in autoimmune disease, whereby

144 ering of arthritis, completely abrogated the protective effect of IFN-alpha.

145 in vitro We therefore hypothesized that the protective effect of IFN-gamma against F. tularensisin v

146 atest HIV RNA level had little impact on the protective effect of immediate cART on infection-related

147 lciparum CelTOS (PfCelTOS), we evaluated the protective effect of in vivo immune responses elicited b

148 Our findings demonstrate a protective effect of increased neuronal uptake of glucos

149 t of the EP4 receptor in mice attenuated the protective effect of intravenous OxPAPC administration i

150 induction plays a key role in mediating the protective effect of laminar blood flow and suggest that

151 guided aortic procedures and highlights the protective effect of leg shielding.

152 The new discoveries regarding the protective effect of lithium against AKI in rodents call

153 observational studies provided evidence of a protective effect of masks (OR = 0.13; 95% CI: 0.03-0.62

154 domized controlled trials (RCTs) indicated a protective effect of masks and respirators against clini

155 Taken together, our results suggest that the protective effect of MCPT4 against GBS dissemination and

156 terial from an untreated mouse abolished the protective effect of microbiota depletion upon renal I/R

157 thrombosis compared to WT mice indicating a protective effect of miR-223 deficiency.

158 tochondrial dysfunction, suggesting that the protective effect of miR-7 is partly exerted through pro

159 We also assessed the protective effect of MR antagonism in IR-induced AKI in

160 This assay allowed detection of the protective effect of NR on small nerve structures in liv

161 he performance of graphene oxide (GO) in the protective effect of olive oil on Bacillus thuringiensis

162 tegic biological barriers, where it exerts a protective effect of paramount importance.

163 our findings reveal that programs reduce the protective effect of parental education on child health,

164 presence of IMF conditionality decreases the protective effect of parents' education on child malnour

165 We also show the marked protective effect of PD-L1 expression on HCV-infected he

166 In addition, we also observed a protective effect of PD-L1-Fc on the placenta by reversi

167 An updated analysis of the short-term protective effect of pertussis vaccines limited to formu

168 Strong epidemiologic evidence documents the protective effect of physical activity on breast cancer

169 quired to confirm and further characterize a protective effect of physical activity on the onset and/

170 completely abolished the blood-brain barrier protective effect of regulatory T cells in vitro.

171 risk following divorce or widowhood, and the protective effect of remarriage against subsequent AUD,

172 FN subversion by RV and reveal an unexpected protective effect of RV infection on endotoxin-mediated

173 e chick embryo, supporting the idea that the protective effect of sildenafil on fetal growth reported

174 Ifng (Sphk2(-/-)Ifng(-/-) mice) blocked the protective effect of SphK2 deficiency in fibrosis.

175 To assess whether the protective effect of statins on the risk of glaucoma var

176 To overcome this, we investigated the protective effect of tauroursodeoxycholic acid (TUDCA),

177 Results verified the protective effect of the Cdh23(c.753G) allele, which pre

178 pathway of CYP142A1, while CIU revealed the protective effect of the heme group on the structure of

179 The mechanisms underlying the protective effect of the ImmunoCloak treatment was evalu

180 The majority of studies show a protective effect of these noble gases on ischemia reper

181 ng an independent data set, we demonstrate a protective effect of this variant against risk of conver

182 Given the protective effect of this variant, PPP4R3A should be fur

183 The protective effect of TPO against the primary oxidation o

184 However, combo treatment abrogated the protective effect of transient BAFFR-Fc monotherapy.

185 The protective effect of TSO was lost in immunosuppressed ra

186 We compared the protective effect of two UV protectant; GO and olive oil

187 We found a strong protective effect of vaccination on preterm birth (relat

188 In further stratified models, the protective effect of younger maternal age in Mexican Ame

189 In subgroup analyses, the protective effect of younger maternal age was observed o

190 e purpose of our study was to understand the protective effects of a partial reduction of dynamin-rel

191 ng the abrogation of AdipoR1 in vitro, these protective effects of adiponectin were abolished.

192 Here, we investigated the protective effects of aminophylline on HDAC2 expression

193 These findings indicated that the protective effects of BAY against Abeta-induced memory d

194 in-3 protein, plays an important role in the protective effects of calpain inhibition for the treatme

195 Overall, the protective effects of CD47 blockade were greater in the

196 ated from CpG-treated mice recapitulated the protective effects of CpG when administered before aller

197 ion of intestinal microbiota, reversed these protective effects of CSA13.

198 han in premenopausal women, perhaps owing to protective effects of estrogens.

199 of autophagic flux is also essential for the protective effects of exendin-4.

200 indicate that autophagy is essential for the protective effects of exercise in the heart.

201 AhR deficiency abolished the protective effects of gammadelta T cells after adoptive

202 nd identify PYK2 as a crucial target for the protective effects of H2S under conditions of oxidative

203 these results mechanistically elucidate the protective effects of HBM and P.

204 Here, we investigated the antiviral protective effects of heat-killed LAB strain Lactobacill

205 Transcriptome analyses showed that the protective effects of high fiber and acetate were accomp

206 n who have had hysterectomies may negate the protective effects of hysterectomy on EOC, creating the

207 The protective effects of marriage on risk for alcohol use d

208 Silencing of NRF2 using siRNA diminished the protective effects of melatonin, while the membrane mela

209 )C]-Metformin and PET/MRI, we found that the protective effects of metformin were OCT1/2 independent

210 thout the 3'-UTR significantly abolished the protective effects of miR-7 against MPP(+)-induced cytot

211 ent inhibitors of Hsp70 function ablated the protective effects of NAC, suggesting that NAC may help

212 l-cysteine and d-cysteine both mimicked the protective effects of NAC, whereas the thiol-lacking mol

213 lutathione depletion failed to attenuate the protective effects of NAC.

214 to the reverse epidemiology hypotheses, the protective effects of obesity were less in patients with

215 barrier enhancement phase and suppressed the protective effects of OxPAPC against more sustained EC b

216 However, the mechanism(s) underlying the protective effects of PARP1 inhibition in colitis and th

217 EP4 mediated barrier-protective effects of PGA2 by activating Rap1/Rac1 GTPas

218 Moreover, the protective effects of podocyte Shp2 deficiency were asso

219 The protective effects of rapamycin are associated with decr

220 e purpose of our study was to understand the protective effects of reduced expression of dynamin-rela

221 Subgroup analyses identified more pronounced protective effects of residential density among individu

222 However, BBB protective effects of Slit2 following SBI has not been e

223 STHdh (Q111) cell model, we investigated the protective effects of small molecule probes having diver

224 After 6-month storage, protective effects of some additives (palm sugar, erythr

225 Persistent and protective effects of SPI diets on OVX-induced bone loss

226 Our findings do not corroborate observed protective effects of testosterone on cognitive function

227 ese data provide a mechanistic basis for the protective effects of the antibody in vitro and in vivo,

228 be one of many elements contributing to the protective effects of the human microbiome.

229 ve of our study was to better understand the protective effects of the mitochondria-targeted tetra-pe

230 The protective effects of this activating receptor therefore

231 These protective effects of TRPV4 channel inhibition were attr

232 Protective effects of UV-B radiation against nonmelanoma

233 Overall, our results demonstrate the protective effects of vitamin D supplementation in block

234 Given the apparently protective effects of VitD and the deleterious associati

235 ton, a 5-LOX inhibitor with VPC reversed the protective effects of VPC against neuroinflammation.

236 as 2 mo, suggesting that GRP78 could exert a protective effect on acinar cells under stress, as durin

237 Autophagy has a protective effect on acute liver injury.

238 0 units per km(2), residential density had a protective effect on adiposity and was associated with l

239 ; 95% CI, 0.9-1.18), yet a tendency toward a protective effect on cardiac death was observed (RR, 0.7

240 FK866 exhibits a protective effect on D-galactosamine (GaIN)/lipopolysacc

241 diabetes, a higher BMI appeared to confer a protective effect on DR, while higher WHR was associated

242 A protective effect on increased suicidal risk was found f

243 For a more profound examination of this protective effect on joint cells, we pursued studies wit

244 gested that higher protein intake may have a protective effect on lumbar spine (LS) bone mineral dens

245 N: Appropriate therapy was associated with a protective effect on mortality among patients with BSIs

246 Furthermore, Rac1 inhibition had a direct, protective effect on podocyte barrier function.

247 bility variants in PLCE1 and ATP2B1 confer a protective effect on risk of developing anthracycline-re

248 -regulated mitoIK, ATP, conferring diazoxide protective effect on T3-treated hESC-VCMs.

249 ropose a mechanism by which Psb28 exerts its protective effect on the RC47 intermediate.

250 Statins have been suggested to have a protective effect on venous thromboembolism (which inclu

251 APOE epsilon2/epsilon3 genotype conferred a protective effect on women (OR, 0.51; 95% CI, 0.43-0.61)

252 rial function in alpha-cells exerts potently protective effects on beta-cells, preserving beta-cell v

253 PQQ supplementation has persistent long-term protective effects on developmental programming of hepat

254 Adiponectin had, however, some protective effects on ovarian function.

255 Treatment with PD-L1-Fc posed protective effects on pre-eclamptic models, indicating t

256 tage renal tubular HIF-2alpha activation has protective effects on renal fibrosis and the resultant r

257 It was found that antioxidants had protective effects on the oocytes in terms of nuclear ma

258 naling involves central pathways with direct protective effects on the perinatal brain.

259 In vivo, Parkin has significant protective effects on the survival and function of nigra

260 r conditioning paradigm, early-life FGF2 has protective effects only in resilient animals.

261 ansfer experiment showed that this arthritis-protective effect operated during the priming of T cells

262 The protective effect persisted after 12 months of avoiding

263 This renal protective effect persisted despite the presence of unde

264 ily dosage or type of statin and whether any protective effect persists after accounting for baseline

265 Importantly, these protective effects produced by XMJ were abolished by eNO

266 of T6SS effector proteins that mediate this protective effect remain poorly defined.

267 However, the underlying mechanisms of this protective effect remain unclear.

268 nt for DN, but the mechanisms underlying the protective effect remain unknown.

269 ences in gene expression that modulate these protective effects remain largely unknown.

270 This protective effect remained after adjusting for demograph

271 CpG DNA (CpG) from bacteria reproduces these protective effects, suggesting a major contribution of C

272 dosages or types of statin confer a greater protective effect than others.

273 rotective influence of MSH2, producing a net protective effect that promotes immune diversification w

274 Statins may exert cardiovascular protective effects that are independent of LDL-cholester

275 side of the operating room may likewise have protective effects that decrease the risk of respiratory

276 ependent, while also revealing an additional protective effect through elevating elastin synthesis.

277 esults identify that miR146a exerts a kidney protective effect through negative regulation of acute i

278 Studies suggest that NGB exerts protective effects to neuronal cells and is implicated i

279 BK seems to permit the protective effects triggered by cinaciguat, riociguat, a

280 The mechanism underlying this apparent protective effect warrants further study.

281 addition to improved energy metabolism, this protective effect was associated with an attenuation of

282 This protective effect was associated with decreased muscle i

283 This protective effect was further promoted by increasing the

284 e against rejection-related graft loss, this protective effect was lost among recipients with persist

285 The protective effect was lost in Gpbar1(-/-) mice.

286 The protective effect was more pronounced for PB than LC-DG

287 A protective effect was observed for the fetal NOG1 SNP on

288 mum recovery of isoflavonoids with high cyto-protective effect was optimised by response surface meth

289 This protective effect was strongest for exposure to antigens

290 ute pneumonia was confirmed in vivo when the protective effect was suppressed by treating glutathione

291 Furthermore, this protective effect was suppressed when antioxidant defens

292 These protective effects were abolished in mice with endotheli

293 Structural and functional protective effects were found for an acute model of ligh

294 genes in both the duodenum and lung, and its protective effects were lost in both Ifnar1(-/-) and ger

295 xtracellular LPS binding capability, and the protective effects were not related to HDL pool size in

296 with systemic corticosteroids revealed that protective effects were seen in participants with baseli

297 in the case of whole body fat, for which the protective effects were stronger in men.

298 geting TSG-6 after CNS injury to promote its protective effects while reducing the inhibitory propert

299 ciated with cardiotoxicity risk conferring a protective effect with a 64% (95% CI: 0.18-0.76, P = 0.0

300 amine withdrawal resulted in a 5- to 10-fold protective effect with chemotherapy treatment.