ライフサイエンスコーパス: psoriasin

1 able for determining physiological levels of psoriasin.

2 Overexpression of S100A7 (psoriasin), a small calcium-binding protein, has been as

3 S100A7/psoriasin, a member of the epidermal differentiation com

4 To date, the exact physiological function of psoriasin abundant in many human cell types remains uncl

5 Urinary psoriasin and beta-defensin antimicrobial peptide levels

6 noma in situ) mammary epithelial cells, that psoriasin and several other genes implicated in psoriasi

7 Psoriasin and several other tightly linked 1q21 genes we

8 , human beta-defensin-3, cathelicidin LL-37, psoriasin) and cytokines (TSLP, IL-25, IL-32, IL-33) wer

9 The hS100A7 (psoriasin) and S100A15 reside in a chromosomal cluster o

10 a setting in which the angiogenic effects of psoriasin are most important.

11 Analysis of synthetic psoriasin by size exclusion chromatography showed that t

12 plification of 121-bp sequence colinear with psoriasin cDNA, as did genomic DNA from hybrid cell line

13 on and TSLP expression (P = 0.02) as well as psoriasin expression (P = 0.016).

14 Correlating with this, high psoriasin expression in human IBC is associated with inc

15 onfluent conditions dramatically up-regulate psoriasin expression in MCF10A mammary epithelial cells.

16 Psoriasin expression is associated with poor prognostic

17 This hypothesis may explain why psoriasin expression is highest in high-grade and/or est

18 , we show that down-regulation of endogenous psoriasin expression via stable short hairpin RNAs in a

19 nsight into regulatory pathways that control psoriasin expression, we developed polyclonal and monocl

20 labelling and demonstrated quantification of psoriasin from 250 pg ml(-1) to 10 ng ml(-1)-a concentra

21 S100A7 (psoriasin), functions as a transglutaminase substrate/co

22 The psoriasin gene was present on a 380-kb yeast artificial

23 isms that may account for elevated levels of psoriasin in DCIS.

24 al putative functions have been proposed for psoriasin in various disease types, but none of these ca

25 y be responsible for increased expression of psoriasin in vitro and in vivo.

26 nalysis indicated that the alpha-helicity of psoriasin increases by more than 20% in the presence of

27 immune response with increased expression of psoriasin, interleukin-1beta, tumor necrosis factor alph

28 Psoriasin is an abundant low molecular weight protein in

29 analysis of breast carcinomas confirmed that psoriasin is frequently overexpressed in estrogen recept

30 S100A7 (psoriasin) is an important member of this family that is

31 Human S100A7 (psoriasin) is overexpressed in inflammatory diseases.

32 S100A7, also called psoriasin, is a member of the S100 multigene family that

33 killing by ZnCl(2) is comparable to that of psoriasin isolated from its natural source.

34 spectively, observed in cells with decreased psoriasin levels compared with controls.

35 Based on these results, we propose that psoriasin may play a role in breast tumor progression by

36 chromosomal band 1q21, we hypothesized that psoriasin might also map to this region.

37 angiogenesis and worse clinical outcome, and psoriasin mRNA levels are coordinately regulated with VE

38 ally synthesized the N-terminally acetylated psoriasin of 100 amino acid residues using solid phase p

39 ta6 subunit cytoplasmic tail and report that psoriasin (Psor) (S100A7) bound preferentially to the re

40 ort by Schroder and colleagues suggests that psoriasin, purified from human stratum corneum extracts,

41 Psoriasin (S100A7) is expressed in several epithelial ma

42 normal T-cell expressed and secreted)], and psoriasin (S100A7) more significantly than Vit-D.

43 Psoriasin (S100A7) was identifi;ed as a gene highly expr

44 Human psoriasin (S100A7), a member of the S100 family of calci

45 of a label-free immunosensor for the protein psoriasin (S100A7), which is associated with a number of

46 ynthetic access to large quantities of human psoriasin should facilitate studies of its biological fu

47 f highly pure and correctly folded synthetic psoriasin was obtained from a single synthesis on a 0.25

48 Antibodies to psoriasin were immobilised onto screen-printed carbon el