ライフサイエンスコーパス: retina

1 essing amacrine cells (VG3-ACs) in the mouse retina.

2 ge related macular degeneration, AMD) in the retina.

3 -dihydroxyphenylacetic acid (DOPAC) in mouse retina.

4 sustained alpha ganglion cells in the mouse retina.

5 stinct set of feature detectors in the mouse retina.

6 ne telodendria in adult and larval zebrafish retina.

7 ritic stratification of neurons in the inner retina.

8 eliably measure DA turnover in the mammalian retina.

9 ible for long-range coherent activity in the retina.

10 ter towards the dorso-temporal region of the retina.

11 is predominantly expressed in the brain and retina.

12 equal double cones compared with the ventral retina.

13 ecordings from 62 ON-OFF DSGCs in the rabbit retina.

14 or their spatial distribution throughout the retina.

15 tina and highest densities in the peripheral retina.

16 visual cortex while visually stimulating the retina.

17 gment epithelium (RPE) to support the neural retina.

18 ion of vasomotor response in the nondiabetic retina.

19 to ganglion cell connection in the mammalian retina.

20 endritic branches in both dorsal and ventral retina.

21 activated CD4(+) T cells that infiltrate the retina.

22 d synaptic markers in fetal human and Macaca retina.

23 in adult rabbits while preserving the inner retina.

24 structural and functional alterations of the retina.

25 nglion cells extend dendrites into the outer retina.

26 nsive study of K2P channel expression in the retina.

27 ossibly mispositioning of cone nuclei in the retina.

28 one photoreceptor mosaic in the living human retina.

29 reporter mouse peaked in the mid-peripheral retina.

30 ow non-uniform distribution across the mouse retina.

31 ed to the apical side and is taken up by the retina.

32 it-level encoding of motion direction in the retina.

33 s to process visual information in the inner retina.

34 organism to study the function of EYS in the retina.

35 somata and arborize in various levels of the retina.

36 the neuronal and vascular components of the retina.

37 ss in the eye occurring entirely outside the retina.

38 nd cell body, and increased apoptosis in the retina.

39 Visual processing starts in the retina.

40 erent cell types and subcellular location of retina.

41 n reducing the amount of VEGF present in the retina.

42 port between photoreceptors and cells in the retina.

43 A1) was the only chromophore detected in the retina.

44 en implicated in impaired development of the retina.

45 ear the fovea) to 1,000 microm in peripheral retina.

46 opment in the fovea compared with peripheral retina.

47 photothermal signal from the melanin in the retina.

48 and co-localizes with S-opsin in the ventral retina.

49 ants derived from different quadrants of the retina.

50 of features available simultaneously on the retina.

51 ates to the apical side to nourish the outer retina.

52 spanning the inner two layers of the rabbit retina.

53 " condition but one that involves the entire retina.

54 t immediately associated with the stomatopod retina.

55 s been shown to start at later stages in the retina.

56 f visual impairment that affects the central retina.

57 rcuit-level neuronal plasticity in the adult retina.

58 re also detected in the RPE of healthy human retina.

59 s in the peripheral nervous system (PNS) and retina.

60 testinal organoids (HIOs), colon mucosa, and retina.

61 nsmission via Gbetagamma in tiger salamander retinas.

62 Stargardt disease and is evidenced in human retinas.

63 increased ERp29 and calreticulin in diabetic retinas.

64 l ganglion cell (RGC) fate in the developing retina?

65 We conclude that RDH10 is not the dominant retina 11-cis-RDH, leaving its primary function in the r

66 ; OCT angiography of the 6 x 6-mm perifoveal retina; 30 degrees and 12 degrees central visual fields;

67 -selective ganglion cells (ooDSGCs) in mouse retina acquire their bistratified dendrites, in which re

68 Zebrafish spontaneously regenerate the retina after injury.

69 We described 3 types of folds in the retina and a crease in the outer retina associated with

70 fection, antigen-specific T cells access the retina and autoimmune uveitis ensues.

71 markable feature of human vision is that the retina and brain have evolved circuitry to extract usefu

72 eostasis and ultimately cell survival in the retina and brain.

73 acterized by a vertical stalk that spans the retina and branches in each retinal layer.

74 in the iris in cases 1, 3, and 4; the neural retina and choroid in case 1; and in the optic nerve in

75 gets and surrounding tissues (such as neural retina and choroid).

76 se 2C promote neovascularization in both the retina and choroid, which suggests that inhibition of th

77 ates, nonuniform opsin expression across the retina and coexpression in single cones creates a mostly

78 , freely moving mice and at the level of the retina and dorsal lateral geniculate nucleus (dLGN).

79 primate visual system, where neurons in the retina and dorsal lateral geniculate nucleus of the thal

80 raphy with very low densities in the central retina and highest densities in the peripheral retina.

81 erent developmental time points in the mouse retina and identified five types of ORDs originating fro

82 lliculus (SC) receives direct input from the retina and integrates it with information about sound, t

83 e specific neural circuits that begin in the retina and mediate this important behaviour remain uncle

84 lta retinal ganglion cells in the guinea pig retina and monitored synaptic currents that were evoked

85 plantation revealed unexpected damage to the retina and optic nerve in chemically burned eyes.

86 iverse range of pathological features in the retina and other organs.

87 characteristics of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) involving

88 rized tissue with associated traction on the retina and sometimes hemorrhage.

89 sfunction, and angiogenesis, its role in the retina and the factors that regulate its actions are not

90 etinal pigment epithelium, outer part of the retina and the optic nerve head within 24-hours, in both

91 factors can have long-lasting effects on the retina and the optic nerve.

92 The interface between the neural retina and the retinal pigment epithelium (RPE) is criti

93 ags that are distributed in gradients in the retina and the tectum.

94 RGCs) are the sole projecting neurons of the retina and their axons form the optic nerve.

95 2 deletion, PKM1 is upregulated in the outer retina and there is increased expression of genes involv

96 trol distribution of drugs from blood to the retina and thereby influence drug efficacy and toxicity.

97 nd sub-cellular localization of IFT43 in the retina and transiently transfected cells was examined by

98 g glaucoma-associated protein changes in the retina and vitreous humour.

99 athogenic variants in genes expressed in the retina and/or brain and consistent with the pattern of i

100 biallelic RPE65 mutations, sufficient viable retina, and ability to perform standardised multi-lumina

101 ntered the cells of the conjunctiva, cornea, retina, and sclera after subconjunctival delivery.

102 ed eye tissues from the conjunctiva, cornea, retina, and sclera were performed to determine the distr

103 ed in AII amacrine cells in the mature mouse retina, and which conjointly identify this retinal cell

104 l Zeiss Meditec) and the modified Heidelberg Retina Angiograph (Heidelberg Engineering) (HRA) at 0.98

105 rees eccentricity with a modified Heidelberg Retina Angiograph HRA2 (scan angle, 3 degrees ).

106 and RPE changes were seen in the peripheral retina, anterior to the vortex veins, in 21.8% of eyes.

107 e systemic circulation (basolateral) and the retina (apical).

108 t regenerated neurons of the adult zebrafish retina are capable of restoring complex morphologies and

109 The centrifugal IOC terminals in the retina are exclusively divergent, resembling the termina

110 The in vivo use of the retina as a surrogate to evaluate brain injury following

111 The retina as an extension of the diencephalon accessible to

112 SH1 and USH2 proteins in the cochlea and the retina as well as the disease mechanisms underlying USH1

113 olds in the retina and a crease in the outer retina associated with papilledema owing to idiopathic i

114 ants of Houston, Houston, Texas; New England Retina Associates, Guilford, Connecticut; Elman Retina G

115 In mouse (ret)Arl13b(-/-) central retina at postnatal day 6 (P6) and older, outer segments

116 Eyes with retinitis involving >/=25% of the retina at presentation detached at nearly 12 times the r

117 yzed for percent of areas of avascular/total retina (AVA) and of intravitreal neovascular/total retin

118 ycoprotein (ABCB1) is expressed at the blood-retina barrier (BRB), where it may control distribution

119 ar antigens are sequestered behind the blood-retina barrier and the ocular environment protects ocula

120 n the retina, endothelial cells form a blood-retina barrier by virtue of tight junctions and low tran

121 The outer blood-retina barrier is established through the coordinated te

122 Treatment-naive eyes enrolled in the Fight Retina Blindness!

123 the red, green, and blue (RGB) cones in the retina, but not in other retinal cell types.

124 t LXA4 and LXB4 are synthesized in the inner retina, but their levels are reduced following injury.

125 e types of thorny ganglion cells in marmoset retina can be identified with antibodies against calreti

126 from January 1 to June 30, 2016, at medical retina clinics at the Singapore National Eye Center amon

127 ose-escalating study done at four outpatient retina clinics in the USA.

128 gments, were significantly lower in diabetic retinas compared to those in controls, suggesting a reti

129 performed in a clinical/surgical setting at Retina Consultants of Houston and Houston Methodist Hosp

130 n Eye Institute, Houston Methodist Hospital, Retina Consultants of Houston, Houston, Texas; New Engla

131 nd one female retina revealed that the human retina contains 7283 +/- 237 melanopsin-ir (0.63-0.75% o

132 esions," the OCT showed a cleft in the outer retina, creating an apical and basal separation of retin

133 In the retina, delay in up-regulation of key photoreceptor gene

134 st that IOP alters multiple functions in the retina depending on the adaptational state.

135 of 2 to 4 distinct vascular plexuses in the retina, depending on location relative to the optic disc

136 t in mouse and rat, and the structure of the retina differs substantially between humans and Drosophi

137 Fluorescence microscopy of wild-type mouse retina disclosed a strong DNM1L expression in the gangli

138 Furthermore, ERG traces from regenerated retinas displayed waveforms matching those of controls,

139 The toxicity to the retina does not seem to be significantly worse in the OA

140 In the vertebrate retina, dopamine is synthesized and released by a specia

141 alized individual rod bipolar cells in mouse retina during postnatal development and quantified the n

142 -AAV2 demonstrated deeper penetration in the retina, efficiently reaching the inner nuclear and outer

143 o the size, speed, and type of motion on the retina, enabling them to occupy different niches in stim

144 In the retina, endothelial cells form a blood-retina barrier by

145 had no effect on the ex-vivo isolated mouse retina ERG where the RPE is not attached to the isolated

146 Like other dichromats, the mouse retina expresses a short-wavelength (S) and a medium-wav

147 The retina extracts visual features for transmission to the

148 In nondiabetic retina, focal stimulation of a pericyte produced a robus

149 trans-retinol (all-trans-ROL)) in the neural retina following a photobleach and 5-fold lower retinyl

150 , teleost fish functionally regenerate their retina following injury, and Muller glia (MG) are the so

151 ersists in restoring visual responses to the retina for almost 1 month after a single intraocular inj

152 ertebrates, it is required not only for lens/retina formation but also for the development of the CNS

153 RGCs and polyaxonal amacrine cells in mouse retina forms the synaptic mechanism responsible for long

154 inhibition prevents progenitor cells of the retina from exiting the cell cycle and differentiating.

155 pochs in the transcriptome dynamics of human retina from fetal day (D) 52 to 136.

156 e novo that protect the fovea of the primate retina from oxidative stress and light damage.

157 Retinas from NIX-deficient mice displayed increased mito

158 somotor response were diminished in diabetic retinas from streptozotocin-treated mice.

159 In the retina, FZD4 and the ligand NDP are critical mediators o

160 ina Associates, Guilford, Connecticut; Elman Retina Group, Baltimore, Maryland; and Retina Research I

161 mental sequence of plexiform layers in human retina has been characterized, the molecular steps of sy

162 The adult mammalian retina has little capacity for regeneration.

163 In contrast, mouse retina has only two opsins, S-opsin and M-opsin, but no

164 system, which projects from the brain to the retina, has been intensively studied in several Neognath

165 emically, cone ERG(absent) RPGRIP1 (ins/ins) retinas have extensive L/M-opsin mislocalization, lack C

166 r glia, the most abundant glia of vertebrate retina, have an elaborate morphology characterized by a

167 In the ventral retina, however, the threshold intensity for M-cone-driv

168 acy results of the Retina Implant Alpha AMS (Retina Implant AG, Reutlingen, Germany) for partial rest

169 o report the initial efficacy results of the Retina Implant Alpha AMS (Retina Implant AG, Reutlingen,

170 on cycle reformats the flow impinging on the retina in a way that initiates coarse-to-fine processing

171 quantify the microstructural changes of the retina in CZS and compare these changes with those of co

172 lliculus (SC) receives visual input from the retina in its superficial layers (sSC) and induces eye/h

173 with thinning of the GCL + IPL sector of the retina in the eyes of patients with MS, particularly tho

174 inal tubulations in degenerated, nonatrophic retina in the majority (69%) of patients.

175 of anesthesia on DA and DOPAC levels in the retina in vivo and find that basal dark-adapted concentr

176 umulation of iron-rich ferritin in the outer retina in-vivo and retinal-pigment-epithelial (RPE) cell

177 k in the radial and tangential planes of the retina, in development and adulthood.

178 reocilia and for melanosome transport in the retina, in line with the phenotypic outcomes observed in

179 ABSTRACT: ON and OFF pathways in the retina include functional pairs of neurons that, at firs

180 e important features reminiscent of a mature retina, including exuberant outgrowth of outer segment-l

181 Brn3b single- and Dlx1/Dlx2 double-knockout retinas, including near total RGC loss with a marked inc

182 c trees of outer stratifying cells cover the retina independent of soma location.

183 In the retina, individual dendritic sectors of a starburst amac

184 increasing antioxidant enzymes activities of retina induced by HFD.

185 degeneration of photoreceptors in the adult retina, interneurons, including bipolar cells, exhibit a

186 hird type of photoreceptors in the mammalian retina, intrinsically photosensitive retinal ganglion ce

187 Given that the retina is a brain-derived tissue, it may provide a nonin

188 ngiogenesis.Pathological angiogenesis in the retina is a major cause of blindness.

189 he view that inhibition of TR locally in the retina is a therapeutic strategy for retinal degeneratio

190 Widespread gene transfer to the retina is challenging as it requires vector systems to o

191 e it is known that the number of ORDs in the retina is developmentally regulated, little is known abo

192 e) and the internal limiting membrane of the retina is essential to understanding the cause of rhegma

193 ent vision loss, and once 25% or more of the retina is involved the risk of RD and visual loss increa

194 me of neuronal organization in the mammalian retina is the segregation of ON and OFF pathways in the

195 li and regulate vascular permeability in the retina is unknown.

196 (AVA) and of intravitreal neovascular/total retina (IVNV).

197 d gamma oscillations with a peak at 60 Hz in retina, lateral geniculate, and primary visual cortex of

198 clature system that is consistent with human retina layer designations to standardize murine OCT, whi

199 mediating lateral inhibition in the central retina, likely horizontal cells, establish functional co

200 We further found that in the dorsal retina, M-cones and melanopsin contribute to dark-adapte

201 ld amacrine cells span large segments of the retina, making them uniquely equipped to normalize and o

202 or cone photopigment within the neurosensory retina may contribute to their favorable course.

203 ding that glucose enters mouse and zebrafish retinas mostly through photoreceptors support a conceptu

204 In the developing retina, multipotent neural progenitors undergo unidirect

205 elevated in response to hyperglycemia in the retina of diabetic rodents.

206 In the retina of DM/hypoxic C57BL/6 mice, abnormal a-wave and b

207 sible to infer some of the properties of the retina of early vertebrate progenitors by comparing lamp

208 idual, spectrally typed cones in the central retina of human observers using adaptive optics.

209 Less VEGF staining was observed within the retina of the eyes treated with ranibizumab when compare

210 I amacrine-->RGC synaptic connections in the retina of the guinea pig (Cavia porcellus) by recording

211 to chronic degenerative changes in the outer retina of these mice.

212 bility, as well as increased levels of CD in retinas of diabetic mice.

213 tional-related proteins were observed in the retinas of diabetic rats, which were significantly chang

214 but decreased antioxidant gene expression in retinas of hyperhomocysteinemic mice.

215 Retinas of mice fed a high fat/sucrose diet also exhibit

216 ic glycolysis and anabolic metabolism in the retinas of mice.

217 In the retinas of streptozotocin-induced diabetic mice, retinal

218 lotting were significantly down-regulated in retinas of STZ-rats and in human diabetic retinas (postm

219 antioxidant and anti-inflammatory effects in retinas of the treated rats, as shown by up-regulation o

220 avitated lamellar separation of neurosensory retina on spectral-domain optical coherence tomography (

221 One eye with detached retina on ultrasound did not actually have a retinal det

222 ut DR showed a thicker choroid and a thinner retina, particularly in inner layers, after 1 year of fo

223 in retinas of STZ-rats and in human diabetic retinas (postmortem) compared with their respective cont

224 Standard models of stimulus encoding in the retina postulate that image presentations activate neuro

225 autopsied eye were conducted at a community retina practice at a university laboratory.

226 here the RPE is not attached to the isolated retina preparation.

227 The two primary axes of the retina project independently onto the tectum using diffe

228 In this report, we investigated the retina-protective effect of chrysophanol, an active comp

229 ptic to the ON sustained alpha cell of mouse retina provide currents with a higher signal-to-noise po

230 s diagnosed with primary DLBCL of the eye or retina (PVRL) or the eyelid, conjunctiva, choroid, cilia

231 In the retina, Rbpr2 loss resulted in shorter photoreceptor out

232 Images were read remotely by a trained retina reader and a glaucoma specialist.

233 The retina reattached during first 4 weeks of follow-up with

234 ts diagnosed with PEVAC were identified at 4 retina referral centers worldwide and underwent complete

235 ed ARL13b expression in the (ret)Arl13b(-/-) retina rescued ciliogenesis.

236 Elman Retina Group, Baltimore, Maryland; and Retina Research Institute of Texas, Abilene).

237 GS, and angio-OCT scans of the peripapillary retina revealed a dense microvascular network.

238 tal cell counts from one male and one female retina revealed that the human retina contains 7283 +/-

239 OFF responses to light, but not in wild-type retinas, revealing selectivity for RGCs that have lost p

240 In the mammalian retina, rod photoreceptors form selective contacts with

241 sources and allows for an examination of the retina's early morphologic changes that are not generall

242 For instance, to quantify the retina's performance, one must consider not only the inf

243 Detection of abnormal flow in the outer retina served as candidate CNV with OCTA.

244 herapy with >1 year follow-up at an academic retina service were included.

245 Surgery (ASCRS) and the American Society of Retina Specialists (ASRS) formed a joint task force to d

246 untarily reported to the American Society of Retina Specialists Research and Safety in Therapeutics (

247 Panel of retina specialists, image reading center experts, retina

248 A panel of retina specialists.

249 to target the Nrl gene, encoding for Neural retina-specific leucine zipper protein, a rod fate deter

250 In primate and human retina such classification has so far, not been applied.

251 ased rhodopsin aggregation in the P23H-1 rat retina, suggesting enhanced P23H misfolding and aggregat

252 Muller glia pERK expression in the detached retina, suggesting that Muller survival pathways might u

253 ignificantly higher in the cone-degeneration retinas, suggesting locally elevated TR signaling.

254 tivity patterns were restored in regenerated retinas, suggesting that regenerated BPs recover accurat

255 wever, that these cells remain in the ageing retina suggests the potential for functional restoration

256 In the adult retina, telodendria are twice as abundant and branch alm

257 pithecus verreauxi indicate a less "diurnal" retina than found in other diurnal primates.

258 notype was found in the Dlx1/Dlx2/Brn3b-null retinas than was predicted by combining features of the

259 c immunocytochemistry, we show in the rabbit retina that bright-light-induced activation of dopamine

260 The fovea is a specialized region of the retina that dominates the visual perception of primates

261 from the retinal vasculature into the inner retina that replenishes the local myeloid cell populatio

262 only a fraction of diseased cells, yielding retinas that are a mosaic of treated and untreated rods,

263 localized to the ganglion cell layer of the retina, the cell type most affected by glaucoma.

264 ree differentially growing compartments: the retina, the ciliary margin (CM), and the retinal pigment

265 ed on the central rod-free region of primate retina, the fovea, to specifically investigate the devel

266 masomes in fully differentiated cells in the retina, the removal of the damaged and dysfunctional mit

267 and functional properties in parallel, from retina through primary visual cortex.

268 ay and regulate the flow of information from retina to cortex.

269 re emphasize the peculiar sensitivity of the retina to perturbations of this pathway, which is highli

270 ns along the visual pathway, from within the retina to the brain.

271 ation of endogenous microglia from the inner retina to the RPE layer, followed by (2) subsequent mono

272 ess corneal imaging by a LS-IVCM (Heidelberg Retina Tomograph 3 with Rostock Cornea Module; Heidelber

273 mpleted within 3 d, and we present data from retinas treated with laser-induced choroidal neovascular

274 cis-RDH, leaving its primary function in the retina unknown.

275 ed JN expression and functional roles in the retina using fluorescence histochemistry, confocal micro

276 nts for bipolar cells (BCs) in the zebrafish retina using in vivo imaging.

277 DH10 is not required for the function of the retina visual cycle.

278 linics between November 2012 and March 2015 (Retina-Vitreous Associates Medical Group, Beverly Hills,

279 In WT retinas, VPA treatment increased histone H3 acetylation.

280 Histological structure of the retina was examined using Hematoxylin and eosin staining

281 dark adaptation both in vivo and in isolated retina was unaffected, indicating that RDH10 is not requ

282 Additionally, in the larval retina, we investigated rod telodendria and UV cone telo

283 Using large-scale recordings in the rat retina, we show that a homogeneous population of fast OF

284 00 bipolar cell axon terminals in the intact retina, we show that bipolar cell functional diversity i

285 Cs) in rod differentiation in neonatal mouse retinas, we used a pharmacological approach that showed

286 Infections of the retina were detected in all mice, and infection of CNS v

287 Vertical cryosections of human retinas were immunostained with antibodies specific for

288 hrough the retinal pigment epithelium to the retina where photoreceptors convert it to lactate.

289 NF-kappaB and Nrf2 signaling pathways in the retina which may contribute to ameliorating retinal dama

290 erall cone density was greater in the dorsal retina which was also characterized by a larger proporti

291 eptor found in the rod outer segments in the retina, which triggers a visual response under dim light

292 Although imaging of the living retina with adaptive optics scanning light ophthalmoscop

293 es, and are reduced twofold in mutant larval retina with few UV cones.

294 cells, unlike neurons, are spread across the retina with homogenous density, and their arbor sizes ch

295 the ellipsoid zone, thinning of the central retina with increased backscatter, and severe structural

296 ectrode recordings in the peripheral primate retina with single-electrode and several types of multi-

297 UV cone telodendria in mutant and transgenic retinas with altered complements of cone types.

298 by which hPSCs can be differentiated into 3D retinas with at least some important features reminiscen

299 pression of IRX1 and ADAMTS16 in human fetal retina, with IRX1 preferentially expressed in fetal macu

300 P channels are widely expressed in the mouse retina, with variations in expression detected at differ