ライフサイエンスコーパス: retinal ischemia

1 ogenesis of diabetic retinopathy, can induce retinal ischemia.

2 on, panretinal photocoagulation, or both for retinal ischemia.

3 9 consecutive patients with MVL secondary to retinal ischemia.

4 cranial nerves and subsequently cerebral and retinal ischemia.

5 retinal neovascularization due to extensive retinal ischemia.

6 ffusivity alone in murine optic nerves after retinal ischemia.

7 protein attenuated Wnt signaling induced by retinal ischemia.

8 , plays a role in neuronal cell death during retinal ischemia.

9 clinically in diseases such as glaucoma and retinal ischemia.

10 RGCs) in animal models of glaucoma and acute retinal ischemia.

11 the occurrence of large contiguous areas of retinal ischemia.

12 n to be involved in the adaptive response to retinal ischemia.

13 e were subjected to 30 minutes of unilateral retinal ischemia.

14 upregulated and may be neuroprotective after retinal ischemia.

15 wn to play a role in cell death in transient retinal ischemia.

16 inal blood flow regulation in patients after retinal ischemia.

17 A and mRNA expression profiles in context of retinal ischemia.

18 expressed and have distinct functions after retinal ischemia.

19 Twenty-four hours after retinal ischemia, A and B waves of vehicle-treated anima

20 athways may prove useful in the treatment of retinal ischemia, a leading cause of vision loss and bli

21 expression with steroids, or alleviation of retinal ischemia, a major stimulus for VEGF expression,

22 Rats were subjected to retinal ischemia after IPC, or retinas were rendered isc

23 romotes the fibrovascular reaction in murine retinal ischemia after laser injury.

24 rimonidine, in animal models of glaucoma and retinal ischemia and in glaucoma patients.

25 tion of retinal ganglion cell (RGC) axons in retinal ischemia and in inducible and hereditary preclin

26 In pathologic settings including retinal ischemia and malignant tumors, robust angiogenes

27 can contribute to capillary obliteration and retinal ischemia and may be a practical target for early

28 was used to evaluate the effects of pHBSP on retinal ischemia and neovascularization (1-30 mug/kg pHB

29 th a selective loss of retinal neurons after retinal ischemia and possibly in glaucoma.

30 The model of retinal ischemia and reperfusion will be a useful tool f

31 fusion and eventual obliteration can lead to retinal ischemia and sight-threatening neovascularizatio

32 index terms: "retinal artery occlusion" OR "retinal ischemia" AND "thrombolysis" OR "fibrinolysis" O

33 stlaminar optic nerve 4 days following acute retinal ischemia, and 3 weeks following the chronic elev

34 Inflammation-mediated leukostasis, retinal ischemia, and neovascularization and their contr

35 The mechanisms of retinal ischemia are not fully understood, however.

36 In a subsequent experiment, total retinal ischemia, as measured by a cessation of electror

37 wth factor (VEGF) levels are correlated with retinal ischemia-associated intraocular neovascularizati

38 d a similar sensitivity to hyperoxia-induced retinal ischemia at P12.

39 Rats were subjected to retinal ischemia by elevation of intraocular pressure.

40 1 were measured in response to RHP and after retinal ischemia by immunoblot analysis and immunohistoc

41 Retinal ischemia can cause vision-threatening pathologic

42 Rats were subjected to 30 or 45 minutes of retinal ischemia followed by reperfusion for up to 48 ho

43 male Lewis albino rats was raised to create retinal ischemia for 1 hour.

44 Retinal ischemia for 5 minutes constituted the precondit

45 (NV) is a sight-threatening complication of retinal ischemia in diabetes, retinal vein occlusion, an

46 sitivity and to correlate with midperipheral retinal ischemia in diabetic subjects.

47 increased intraocular pressure (IOP) and/or retinal ischemia in glaucoma and leads to impairment of

48 outcome of high intraocular pressure-induced retinal ischemia in rats.

49 in the angiogenic response to oxygen-induced retinal ischemia in transgenic mice overexpressing PKC b

50 and immunolocalization analyses showed that retinal ischemia increased expression of the NAD(P)H oxi

51 ion of retinal arterioles was examined after retinal ischemia induced by elevated intraocular pressur

52 dies of rhEPO in a model of transient global retinal ischemia induced by raising intraocular pressure

53 cts at the synaptic level in a model of mild retinal ischemia induced by temporary middle cerebral ar

54 Retinal ischemia-induced upregulation of vascular endoth

55 Because retinal ischemia is a common cause of vision loss, we so

56 Because retinal ischemia is known to increase intracellular aden

57 layed cell death that occurs after transient retinal ischemia is, in part, apoptotic.

58 Mild retinal ischemia led to a significantly higher percentag

59 Diabetic retinal ischemia may be caused, in part, by the adhesion

60 ce protein (gfp+) and subjected to our adult retinal ischemia model.

61 nfirmed in Matrigel plug, wound healing, and retinal ischemia models in vivo.

62 l artery obstruction (n = 2), and peripheral retinal ischemia (n = 2).

63 tration of rhEPO before or immediately after retinal ischemia not only reduced histopathological dama

64 Varying degrees of cardiac involvement and retinal ischemia occurred, with TMA evident on kidney bi

65 At 3 and 7 days after retinal ischemia, optic nerves were removed for CAP meas

66 ed 24 hours earlier with either 5 minutes of retinal ischemia or by exposing conscious animals to hyp

67 Retinal ischemia or IPC was produced in anesthetized Spr

68 de disruption was correlated with peripheral retinal ischemia (P = .025).

69 with chronic vascular arrest and peripheral retinal ischemia persisting beyond standard screening ti

70 Vascular insufficiency and retinal ischemia precede many proliferative retinopathie

71 ut had no measurable effect on the extent of retinal ischemia, preretinal neovascularization, or neur

72 In proliferative diabetic retinopathy (PDR), retinal ischemia promotes neovascularization (NV), which

73 ression plays a neuroprotective role against retinal ischemia reperfusion injury due to decreasing of

74 Using a retinal ischemia reperfusion injury model in mice, we ob

75 Retinal ischemia-reperfusion (IR) injury causes irrevers

76 Retinal ischemia-reperfusion after transient elevated IO

77 he expression of EDG receptors in a model of retinal ischemia-reperfusion injury and also tested LXR-

78 lpha and its receptor in an in vivo model of retinal ischemia-reperfusion injury by investigating its

79 lear layer (INL) was noted in a rat model of retinal ischemia-reperfusion injury by transient elevate

80 ns, and retinal ganglion cells (RGCs) in rat retinal ischemia-reperfusion injury in vivo.

81 The etiology of retinal ischemia-reperfusion injury is orchestrated by c

82 study was conducted to examine the effect of retinal ischemia-reperfusion injury on protein tyrosine

83 Retinal ischemia-reperfusion injury was performed on p55

84 e function was evaluated in a mouse model of retinal ischemia-reperfusion injury.

85 play an important role in neuroprotection in retinal ischemia-reperfusion injury.

86 Streptozotocin-induced diabetes and retinal ischemia-reperfusion models were used in in vivo

87 ystemically or directly into the vitreous of retinal ischemia-reperfusion-injured adult nonobese diab

88 d two models of Bmal1(fx/fx);Tek-Cre mice, a retinal ischemia/reperfusion model and a neointimal hype

89 etabolism has an influence on the outcome of retinal ischemia/reperfusion.

90 Retinal ischemia resulted in significant, duration-depen

91 The pathogenesis of retinal ischemia results from a series of events involvi

92 radial diffusivity was seen at 3 days after retinal ischemia, suggesting axonal injury without myeli

93 A brief period of noninjurious retinal ischemia, termed preconditioning, has been docum

94 In response to the ensuing retinal ischemia, there was consistent preretinal neovas

95 pillaries, lesions that produce irreversible retinal ischemia through their inability to support bloo

96 lts were then applied to an in vivo model of retinal ischemia to determine whether CoCl(2) upregulate

97 aded MnCl(2) was also conducted in eyes with retinal ischemia, to evaluate whether the enhancements r

98 nction of mouse optic nerves after transient retinal ischemia using in vitro electrophysiologic recor

99 Unilateral retinal ischemia was created in Long-Evans and Sprague-D

100 Retinal ischemia was induced 24 hours after either IPC o

101 -1 (50 mg/kg) or vehicle, and then transient retinal ischemia was induced by acute IOP elevation.

102 Retinal ischemia was induced by raising the intraocular

103 Retinal ischemia was induced by transiently raising the

104 Retinal ischemia was induced for 0, 5, 30, 60, 75, or 90

105 Retinal ischemia was induced in 7- to 8-week-old female

106 Retinal ischemia was induced in rats by acutely increasi

107 multilineage reconstitution was established, retinal ischemia was induced to promote neovascularizati

108 e hematopoietic engraftment was established, retinal ischemia was induced to promote neovascularizati

109 Transient retinal ischemia was induced using a high intraocular pr

110 Retinal ischemia was produced for 60 minutes in anesthet

111 Retinal ischemia was produced for 60 minutes in ketamine

112 Retinal ischemia was produced in Lewis rats by increasin

113 tinal neovascularization in animal models of retinal ischemia, we tested whether IGF-I could act as a

114 escein transit time, and the presence of any retinal ischemia were associated with a higher incidence

115 Up-regulation of NOS2 and COX2 after retinal ischemia were blunted in CD40(-/-) mice.

116 egulation of proinflammatory molecules after retinal ischemia were dependent on CD40 expression in th

117 Similar amounts of posterior retinal ischemia were observed in all mice at both PND-1

118 this period of long-term tolerance (LTT) to retinal ischemia were sustained increases in retinal lev

119 nisotropy (RA) progressively decreased after retinal ischemia when compared with that of the controls

120 ed nerves also progressively decreased after retinal ischemia, which correlated with the reduced RA (

121 raphy allowed determination of the extent of retinal ischemia, which was treated with laser photocoag

122 ctive strategy for preventing oxygen-induced retinal ischemia without provoking retinal neovasculariz