ライフサイエンスコーパス: retinal photoreceptor

1 ion cells (pRGCs) represent a third class of retinal photoreceptor.

2 t animals indicate a contribution from inner retinal photoreceptors.

3 ing protein family expressed specifically in retinal photoreceptors.

4 ransported, as earlier proposed, from distal retinal photoreceptors.

5 n of the circadian oscillator in the Xenopus retinal photoreceptors.

6 ession of these motors is highly enhanced in retinal photoreceptors.

7 uires neither rods nor cones, the only known retinal photoreceptors.

8 Ogre is required in the presynaptic retinal photoreceptors.

9 by these genes are expressed exclusively in retinal photoreceptors.

10 cleus is entrained to the day/night cycle by retinal photoreceptors.

11 t negative Xenopus CLOCK specifically in the retinal photoreceptors.

12 egment photocurrents of Lampetra fluviatilis retinal photoreceptors.

13 mplexed with GTP/Talpha in mature vertebrate retinal photoreceptors.

14 alized rhabdomeral membranes from Drosophila retinal photoreceptors.

15 the regulation of cGMP phosphodiesterase in retinal photoreceptors.

16 rons, including hippocampal mossy fibres and retinal photoreceptors.

17 tantially protected from light damage to the retinal photoreceptors.

18 here is a slowly progressive degeneration of retinal photoreceptors.

19 t mammals is thought be mediated entirely by retinal photoreceptors.

20 t/dark cycle is mediated exclusively through retinal photoreceptors.

21 dness result from the dysfunction or loss of retinal photoreceptors.

22 y, distribution, and spectral sensitivity of retinal photoreceptors.

23 s essential for the survival and function of retinal photoreceptors.

24 ted in inflammatory pathologic conditions in retinal photoreceptors.

25 vative bound to rhodopsin and cone opsins of retinal photoreceptors.

26 y sighted subjects can be supported by inner retinal photoreceptors.

27 disease characterized by progressive loss of retinal photoreceptors.

28 mately lead to blindness due to the death of retinal photoreceptors.

29 belief that rods and cones are the exclusive retinal photoreceptors.

30 the inner segment and synaptic terminals of retinal photoreceptors.

31 tenuated the detrimental influence of SNP to retinal photoreceptors.

32 viding cells and to the connecting cilium of retinal photoreceptors.

33 is crucial for the function and survival of retinal photoreceptors.

34 rriers targeted to the rod outer segments of retinal photoreceptors.

35 Crocin protects retinal photoreceptors against light-induced cell death.

36 In retinal photoreceptors, amplification by the phototransd

37 y stereocilia of inner ear hair cells and to retinal photoreceptor and pigmented epithelium cells.

38 gamma) binding protein, highly expressed in retinal photoreceptor and pineal cells, yet whose physio

39 Mice with a 1.8-kb IRBP promoter develop retinal photoreceptor and pineal tumors.

40 transporter has been described in vertebrate retinal photoreceptors and bipolar cells, the molecular

41 els are crucial for synaptic transmission in retinal photoreceptors and bipolar neurons.

42 wide differences in DNA methylation between retinal photoreceptors and brain neurons.

43 o lead to the loss of temporal resolution in retinal photoreceptors and deficient synaptic transmissi

44 Da) matrix protein expressed specifically in retinal photoreceptors and developing cochlear hair cell

45 is required for the long-term maintenance of retinal photoreceptors and for the development of cochle

46 Both SMC1 and SMC3 localized to the cilia of retinal photoreceptors and Madin-Darby canine kidney cel

47 mfort and dazzling glare depend on different retinal photoreceptors and nociceptive brain pathways in

48 Specialized sensory cilia such as retinal photoreceptors and olfactory cilia use diverse i

49 yclic nucleotide-gated (CNG) ion channels of retinal photoreceptors and olfactory neurons are multime

50 tics of light-evoked responses in vertebrate retinal photoreceptors and ON-bipolar cells.

51 involved in differentiation and survival of retinal photoreceptors and photoentrainment of circadian

52 n protein that is expressed predominantly in retinal photoreceptors and pinealocytes.

53 ecoverin expressed in tumor cells may damage retinal photoreceptors and play a role in the pathogenes

54 the retina, is driven synaptically, because retinal photoreceptors and second-order cells tonically

55 Synaptic transmission between retinal photoreceptors and second-order neurones is cont

56 nerating the electrical response to light in retinal photoreceptors and to odorants in olfactory rece

57 The confocal IOS predominantly results from retinal photoreceptors, and can be used to map localized

58 ve is the light-induced hyperpolarization of retinal photoreceptors, and the b-wave is the depolariza

59 prCAD is expressed only in retinal photoreceptors, and the prCAD protein is localiz

60 at following an intraocular injection of SNP retinal photoreceptors are affected.

61 Retinal photoreceptors are highly metabolic and their en

62 fects of drusen on the synaptic machinery of retinal photoreceptors are investigated.

63 Retinal photoreceptors are susceptible to mitochondrial

64 The photoresponse in retinal photoreceptors begins when a molecule of rhodops

65 When applied to retinal photoreceptors, bicarbonate enhanced the circula

66 visually driven signals as they flow through retinal photoreceptor, bipolar, and ganglion cells.

67 -ATPase ("flippase") located in membranes of retinal photoreceptors, brain cells, and testis, where i

68 gene fusion expressed high levels of FGF2 in retinal photoreceptors but developed no retinal neovascu

69 cked the membranous stacks characteristic of retinal photoreceptors but were ciliated and contained n

70 es are being developed to bypass degenerated retinal photoreceptors by directly activating retinal ne

71 5 to inner ear hair cell stereocilia, and to retinal photoreceptors by immunocytochemistry.

72 dition to rods and cones, mammals have inner retinal photoreceptors called intrinsically photosensiti

73 sion of beta-galactosidase (beta gal) on the retinal photoreceptor cell arrestin promoter, in conjunc

74 Circadian shedding of retinal photoreceptor cell discs with subsequent phagocy

75 Mouse retinal photoreceptor cell generation and morphogenesis

76 maintain the blood-retinal barrier, sustain retinal photoreceptor cell health and function, and may

77 Retinal pigment epithelial and retinal photoreceptor cell lines were treated with TP de

78 esis and cohesion of stereocilia bundles and retinal photoreceptor cell maintenance or function.

79 ramide metabolism plays an important role in retinal photoreceptor cell survival and apoptosis.

80 th transgenic mice that expressed betagal in retinal photoreceptor cells (arrbetagal mice).

81 Several proteins found in retinal photoreceptor cells (guanylate cyclase activatin

82 Melatonin is synthesized in retinal photoreceptor cells and acts as a neuromodulator

83 ns-retinal triggers phototransduction in the retinal photoreceptor cells and causes ultimately the se

84 gene promoter are hypomethylated in DNA from retinal photoreceptor cells and pineal gland compared to

85 sorders characterized by degeneration of the retinal photoreceptor cells and progressive loss of visi

86 of Hmgb1 at the protein level occurs in rat retinal photoreceptor cells and to a lesser extent in bi

87 Retinal photoreceptor cells are particularly vulnerable

88 vertebrates is triggered when light strikes retinal photoreceptor cells causing photoisomerization o

89 In vivo, AANAT activity in chicken retinal photoreceptor cells exhibits a circadian rhythm

90 c factors (NTFs) are effective in protecting retinal photoreceptor cells from the damaging effects of

91 ses selective irreversible apoptotic loss of retinal photoreceptor cells in vivo.

92 ngly, an eye with restored cornea, iris, and retinal photoreceptor cells is formed when a surface fis

93 era) visual system contains three classes of retinal photoreceptor cells that are maximally sensitive

94 is a canonical G protein-mediated cascade of retinal photoreceptor cells that transforms photons into

95 links photoactivation of visual pigments in retinal photoreceptor cells to a change in their membran

96 LEDGF enhanced survival of retinal photoreceptor cells under serum starvation and h

97 ects of LEDGF on survival of embryonic chick retinal photoreceptor cells under serum starvation and h

98 hed transgenic mice expressing human E2F1 in retinal photoreceptor cells under the regulation of the

99 pression pattern of LEDGF in embryonic chick retinal photoreceptor cells was investigated with protei

100 vels were both high in the inner segments of retinal photoreceptor cells where energy-demanding activ

101 Melatonin receptors are expressed in retinal photoreceptor cells, and this study was undertak

102 showed that both GCAP genes are expressed in retinal photoreceptor cells, but GCAP2 was nearly undete

103 oA are used as alternative Nmt substrates in retinal photoreceptor cells, even though they do not exh

104 ythmically expressed in the cytoplasm of the retinal photoreceptor cells, the only other described ve

105 Notably, expression is not observed in retinal photoreceptor cells, the opsin-containing cells

106 urnin is rhythmically transcribed in Xenopus retinal photoreceptor cells, which contain endogenous ci

107 r responsible for the capture of a photon in retinal photoreceptor cells.

108 ransduction in olfactory sensory neurons and retinal photoreceptor cells.

109 rtant during phototransduction in vertebrate retinal photoreceptor cells.

110 laevis its mRNA is specifically expressed in retinal photoreceptor cells.

111 -sensitive regulator of phototransduction in retinal photoreceptor cells.

112 MD) leads to dysfunction and degeneration of retinal photoreceptor cells.

113 to adaptation to background illumination in retinal photoreceptor cells.

114 pe voltage-gated Ca(2+) channels (Cav1.4) in retinal photoreceptor cells.

115 te and continuously supply 11-cis-retinal to retinal photoreceptor cells.

116 ion and proper development of hair cells and retinal photoreceptor cells.

117 ndition characterized by progressive loss of retinal photoreceptor cells.

118 n nuclear receptor expressed specifically by retinal photoreceptor cells.

119 such asymmetry in any bird and suggests that retinal photoreceptor composition should be assessed dur

120 While luminance adaptation can begin at the retinal photoreceptors, contrast adaptation has been sho

121 In retinal photoreceptors, coupling plays important roles i

122 right light can cause visual dysfunction and retinal photoreceptor damage in humans and experimental

123 activation of this gene in zebrafish induced retinal photoreceptor defects that were rescued by human

124 ammatory response was associated with marked retinal photoreceptor degeneration and massive neuronal

125 is pigmentosa comprises a group of inherited retinal photoreceptor degenerations that lead to progres

126 eptor gene, NR2E3, cause a disorder of human retinal photoreceptor development characterized by hyper

127 progenitor cell marker, in the biogenesis of retinal photoreceptor disk arrays.

128 ayer morphology, large areas of RPE atrophy, retinal photoreceptor dysfunction, and microglial cell a

129 Retinal photoreceptors entrain the circadian system to t

130 These novel retinal photoreceptors express the photopigment melanops

131 onses to Arm signaling that specify distinct retinal photoreceptor fates.

132 mon causes of blindness involve the death of retinal photoreceptors, followed by progressive inner re

133 ead throughout the CNS and is observed among retinal photoreceptors from essentially all vertebrates.

134 functional cell monolayer that separates the retinal photoreceptors from the choroid, are prevalent i

135 -expressing ipRGCs, showing that these inner retinal photoreceptors function as retinal irradiance de

136 In retinal photoreceptors, highly polarized organization of

137 dimension to an essential role for LPCAT1 in retinal photoreceptor homeostasis.

138 sed on the differential color sensitivity of retinal photoreceptors, however the developmental progra

139 Retinal photoreceptors in Cep290(ko/ko) mice lack connec

140 E) performs specialized functions to support retinal photoreceptors, including regeneration of the vi

141 ory light avoidance behavior in mice lacking retinal photoreceptors, indicating reconstitution of lig

142 age formation, the light that is detected by retinal photoreceptors influences subcortical functions,

143 al photoreceptors (rods and cones) and inner retinal photoreceptors (intrinsically photosensitive ret

144 The cGMP-specific phosphodiesterase (PDE) of retinal photoreceptors is a central regulatory enzyme in

145 n vivo, the circadian clock localized in the retinal photoreceptors is necessary for its rhythmicity.

146 nes constitute approximately 1% of adult rat retinal photoreceptors, it was estimated that the relati

147 In retinal photoreceptors, L-VGCCs are responsible for neur

148 SNP caused an increase in the number of retinal photoreceptors labeled for DNA breakdown by the

149 o have potential for success but only if the retinal photoreceptor layer is intact, as in the early-d

150 pically, patients lose vision when the outer retinal photoreceptor layer is lost, and so the therapeu

151 ian rhythm of melatonin synthesis in Xenopus retinal photoreceptor layers is driven by rhythmic chang

152 in the circadian system in cultured Xenopus retinal photoreceptor layers.

153 eins of the EF-hand superfamily that inhibit retinal photoreceptor membrane guanylyl cyclase (retGC)

154 ,5'-monophosphate phosphodiesterase (PDE) in retinal photoreceptors, must be deactivated for the ligh

155 ion is achieved by comparing the inputs from retinal photoreceptor neurons that differ in their wavel

156 In contrast, neither RH5-expressing retinal photoreceptors nor RH2-expressing ocellar photor

157 ning electron microscopy to characterize the retinal photoreceptors of spine-bellied (Lapemis curtus)

158 A circadian clock is located in the retinal photoreceptors of the African clawed frog Xenopu

159 degeneration of cerebellar Purkinje neurons, retinal photoreceptors, olfactory bulb mitral neurons, a

160 Visual transduction in retinal photoreceptors operates through a dynamic interp

161 These results indicate that a rhythm of retinal photoreceptor outer segment disk shedding exists

162 acts access to the confined space within the retinal photoreceptor outer segment signaling compartmen

163 (TLRs) in the innate immune response causes retinal photoreceptor oxidative stress and mitochondrial

164 sion, when mutated can result in an isolated retinal photoreceptor phenotype.

165 Retinal photoreceptor phosphodiesterase (PDE6) is unique

166 In vertebrate retinal photoreceptors, photoisomerization of opsin-boun

167 study was undertaken to investigate whether retinal photoreceptor (PR) cells lacking MTs are more su

168 Circadian oscillators in retinal photoreceptors provide a mechanism that allows p

169 Despite the loss of all known retinal photoreceptors, rd/rd cl mice showed normal supp

170 Timely termination of the light response in retinal photoreceptors requires rapid inactivation of th

171 In retinal photoreceptors, RGS9.Gbeta5 is bound to the memb

172 Both outer retinal photoreceptors (rods and cones) and inner retina

173 on within the protein-coding region of a new retinal photoreceptor-specific gene, ELOVL4, in all affe

174 acterize transgenic protein localization and retinal photoreceptor structure and function.

175 Gap junctions in retinal photoreceptors suppress voltage noise and facili

176 Transplantation of fetal retinal photoreceptor suspensions into the subretinal sp

177 ion cells (ipRGCs) comprise a third class of retinal photoreceptors that are known to mediate physiol

178 Light produces a graded hyperpolarization in retinal photoreceptors that decreases their release of s

179 In mammals, pineal function is influenced by retinal photoreceptors that project to the suprachiasmat

180 In vertebrate retinal photoreceptors, the absorption of light by rhodo

181 the intrinsic ability of regenerating adult retinal photoreceptors to reconstitute properly differen

182 The outer segments of vertebrate retinal photoreceptors undergo periodic shedding of memb

183 Retinal photoreceptors use the heterotrimeric G protein

184 In retinal photoreceptors, vectorial transport of cargo is

185 al visual structures by receiving input from retinal photoreceptors via bipolar and amacrine cells.

186 to supply 11-cis-retinal from the RPE to the retinal photoreceptors was accompanied by a massive accu

187 To stimulate different retinal photoreceptors, we used a 1-second 640-nm flash

188 In retinal photoreceptors where rootlets appear particularl

189 Rac1 is expressed abundantly in mammalian retinal photoreceptors, where it is activated in respons

190 observations, we show here that adult mouse retinal photoreceptors, which are terminally differentia

191 occur through either extraretinal (brain) or retinal photoreceptors, which mediate sensitivity to blu

192 ataract removal, we have found evidence that retinal photoreceptors will swiftly realign towards the