ライフサイエンスコーパス: retinal pigment epithelial cell

1 lytic cleavage before internalization by the retinal pigment epithelial cell.

2 modulate the proliferative potential of the retinal pigment epithelial cell.

3 onset degeneration of rod photoreceptors and retinal pigment epithelial cells.

4 reased SCD mRNA expression in cultured human retinal pigment epithelial cells.

5 d2 phosphorylation in TGF-beta-treated human retinal pigment epithelial cells.

6 of the vascular complex, surrounded by FasL+ retinal pigment epithelial cells.

7 rrogate support functions usually adopted by retinal pigment epithelial cells.

8 y for cell-to-cell spread in polarized human retinal pigment epithelial cells.

9 ome posterior retinal blood vessels and some retinal pigment epithelial cells.

10 tor-5 also stimulated proliferation of human retinal pigment epithelial cells.

11 ory concentration (IC(5)(0)) of 20 mug/mL in retinal pigment epithelial cells.

12 angiogenesis and a cytoprotective agent for retinal pigment epithelial cells.

13 cessing, and reduced cathepsin D activity in retinal pigment epithelial cells.

14 ured retinal capillary endothelial cells and retinal pigment epithelial cells.

15 ORF45 tegument protein were tested in human retinal pigment epithelial cells.

16 ffects of increased iron on the functions of retinal pigment epithelial cells.

17 al pericytes, retinal endothelial cells, and retinal pigment epithelial cells.

18 m (pCRP) upregulates IL-8 and CCL2 levels in retinal pigment epithelial cells.

19 ious uveitis and that IL-22 can affect human retinal pigment epithelial cells.

20 ar cell types, human trabecular meshwork and retinal pigment epithelial cells.

21 -226, human leukemia cells, HL-60, and human retinal pigmented epithelial cells.

22 of blood vessels surrounded by proliferated retinal pigmented epithelial cells.

23 cule isolated from mammalian endothelial and retinal pigmented epithelial cells.

24 s and forms fewer atypical fibers with human retinal pigmented epithelial cells.

25 erferon-gamma, to increase CFH expression in retinal pigmented epithelial cells.

26 Over time, the Mreg(-/-) mouse retinal pigment epithelial cells accumulate the lipofusc

27 ctivation had a moderate effect on enhancing retinal pigmented epithelial cell adhesion and migration

28 Using spontaneously immortalized human retinal pigment epithelial cells (adult retinal pigment

29 The MFAO-2s protect human neuroblastoma and retinal pigmented epithelial cells against hydroxyl radi

30 Retinal pigment epithelial cells and cells in the inner

31 isolated a novel, high Mr protein from human retinal pigment epithelial cells and endothelial cells b

32 telomerase-negative normal human cell types, retinal pigment epithelial cells and foreskin fibroblast

33 +)AT and 4F2hc or b(0,+)AT and rBAT in human retinal pigment epithelial cells and in COS-1 cells.

34 poptotic debris by monocytes/macrophages and retinal pigment epithelial cells and is capable of produ

35 ound to be required for viral replication in retinal pigment epithelial cells and microvascular endot

36 lial cells, whereas AdV5-GFP transduced only retinal pigment epithelial cells and occasional photorec

37 ) and pigment changes indicative of reactive retinal pigment epithelial cells and photoreceptor degen

38 The RPE65 protein is located in the retinal pigment epithelial cells and plays an important

39 fibrovascular, retrolental tissue containing retinal pigment epithelial cells and remnants of the hya

40 talloproteinase (MMP) inhibitory activity in retinal pigment epithelial cells and resulted in increas

41 d from rod outer segment-challenged, control retinal pigment epithelial cells and zif-268, AP-1, AP-2

42 rase (LRAT), an enzyme present mainly in the retinal pigmented epithelial cells and liver, converts a

43 In 2 wk, we generated both retinal pigmented epithelial cells and self-forming neur

44 luated in Muller cells (rMCs), primary mouse retinal pigment epithelial cells, and astrocytes.

45 to individual cells, such as photoreceptors, retinal pigment epithelial cells, and blood cells in the

46 d bone morphogenetic protein-4 expression in retinal pigment epithelial cells, and both bone morphoge

47 various cell lines including hepatoma cells, retinal pigment epithelial cells, and keratinocytes as w

48 sed in three cell types: dermal fibroblasts, retinal pigment epithelial cells, and vascular endotheli

49 We disrupted CETN2 in human retinal pigmented epithelial cells, and despite having i

50 lines, including lung and skin fibroblasts, retinal pigmented epithelial cells, and endometrial stro

51 specifically localized to renal medulla and retinal pigmented epithelial cells, and it was prominent

52 Retinal pigment epithelial cells appear to demonstrate a

53 ular lipofuscin granules isolated from human retinal pigment epithelial cells are examined by using s

54 inoid lipofuscin pigments that accumulate in retinal pigment epithelial cells are implicated in the e

55 proton beam radiation, retinal ganglion and retinal pigment epithelial cells are preserved while cho

56 Our results indicate that retinal pigment epithelial cells are the initial site of

57 angiogenic factor IL-1beta strongly, whereas retinal pigment epithelial cells are the main source of

58 y cultured epithelial cells, such as ARPE-19 retinal pigmented epithelial cells, are poorly infected

59 Retinal pigment epithelial cells (ARPE-19 and B6-RPE07)

60 Human retinal pigment epithelial cells (ARPE-19) and rat neuro

61 stress on the ability of immortalized human retinal pigment epithelial cells (ARPE-19) to regulate c

62 Formation of lipid rafts in cultured human retinal pigment epithelial cells (ARPE-19) was studied b

63 Human retinal pigment epithelial cells (ARPE-19) were cultured

64 Retinal pigment epithelial cells (ARPE-19) were cultured

65 glion cells (RGC-5), and serum-starved human retinal pigment epithelial cells (ARPE-19) were exposed

66 ynonenal, and peroxynitrite) for human adult retinal pigment epithelial cells (ARPE-19) were quantifi

67 haracterized NORPEG, a novel gene from human retinal pigment epithelial cells (ARPE-19), in which its

68 VR in the experimental model, and from human retinal pigment epithelial cells (ARPE-19).

69 (alphaB) is exported out of the adult human retinal pigment epithelial cells (ARPE19) packaged in ex

70 The bis-retinoid pigments that accumulate in retinal pigment epithelial cells as lipofuscin are assoc

71 r senescence in normal human fibroblasts and retinal pigment epithelial cells, as ectopic expression

72 ic towards human primary blood leukocytes or retinal pigment epithelial cells at effective concentrat

73 can act as an oxidative stressor leading to retinal pigment epithelial cell atrophy.

74 tends the life span of human fibroblasts and retinal pigment epithelial cells beyond senescence witho

75 rowth of bovine retinal pericytes (BRPs) and retinal pigment epithelial cells (BRPECs) were evaluated

76 ells, macrophages, choroidal fibroblasts and retinal pigment epithelial cells, but also on the expres

77 We show that tenascin-C is anti-adhesive for retinal pigmented epithelial cells, but after integrin a

78 we show that IL-22 can affect primary human retinal pigment epithelial cells by decreasing total tis

79 whether manipulation of integrin function in retinal pigment epithelial cells can restore their adhes

80 lso tested against the noncancerous ARPE-19 (retinal pigment epithelial cells) cell line, in order to

81 d in Royal College of Surgeons-p+ dystrophic retinal pigment epithelial cells challenged with rod out

82 alpha1beta1 localizes to the basal aspect of retinal pigment epithelial cells colocalizing with the b

83 Ectopic expression of ngn2 in nonneural, retinal pigment epithelial cell culture triggered de nov

84 Retinal pigment epithelial cell cultures prepared from R

85 ven the key role of oxidative stress-induced retinal pigment epithelial cell death and secondary phot

86 the virus uses two different routes to enter retinal pigmented epithelial cells, depending on the cel

87 Retinal pigment epithelial cells did not stain for iNOS.

88 rapidly and transiently increased in normal retinal pigment epithelial cells during rod outer segmen

89 roles in the stimulation of fibroblasts and retinal pigment epithelial cells during the formation of

90 espread drusen deposition is associated with retinal pigmented epithelial cell dysfunction and degene

91 ic ath5 expression in cultures of non-neural retinal pigment epithelial cells elicited transdifferent

92 eptide loaded nanotube were non-cytotoxic to retinal pigment epithelial cells even at a concentration

93 MREG-deficient human and mouse retinal pigment epithelial cells exhibit diminished acti

94 Human retinal pigment epithelial cells exposed to superoxide o

95 Cloned retinal pigment epithelial cells expressed the IGF-1 tra

96 Evaluation of retinal pigment epithelial cell extracts derived from E-

97 that OCRL localizes to the primary cilium of retinal pigment epithelial cells, fibroblasts and kidney

98 LEDGF1-326 also increased retinal pigment epithelial cell FluoSphere uptake to 140

99 , or thrombospondin and incubated with human retinal pigment epithelial cells for 3 hours.

100 Retinal pigment epithelial cells from normal and RCS rat

101 It has been shown that allografts of retinal pigment epithelial cells from normal perinatal r

102 Retinal pigment epithelial cell heights were measured on

103 ional importance of alpha1beta1 integrin for retinal pigment epithelial cell homeostasis and retinal

104 Glucose consumption of HRECs, human retinal pigment epithelial cells (HRPEs), and human Mull

105 lion cells, Muller cells, photoreceptors and retinal pigment epithelial cells in a spatial arrangemen

106 ecreases senescence-associated phenotypes in retinal pigment epithelial cells in culture.

107 the phagocytosis and lysosomal functions of retinal pigment epithelial cells in the aged RPE/choroid

108 ar (geographic) atrophy frequently occurs in retinal pigment epithelial cells in the human disease, a

109 Reoxygenation of human retinal pigment epithelial cells in vitro and ocular rep

110 rates paracrine biological activity in human retinal pigment epithelial cells in vitro.

111 sults show that B(e)P is a toxicant to human retinal pigment epithelial cells in vitro.

112 s of approximately 40% of the animals and in retinal pigmented epithelial cells in 4 animals.

113 Retinal pigmented epithelial cells in the eye produce re

114 eased intracellular iron on the functions of retinal pigment epithelial cells, in vitro ARPE-19 cells

115 is not significantly activated by hypoxia in retinal pigment epithelial cells, indicating that ERK5 r

116 rion assembly compartments in differentiated retinal pigment epithelial cells, infected AmEpCs made d

117 The role of AMPK in retinal pigment epithelial cell inflammatory response is

118 Our results suggest that manipulation of retinal pigment epithelial cell integrins through integr

119 ototoxic doses of light with NACA maintained retinal pigment epithelial cell integrity and prevented

120 N) was detected in the conditioned medium of retinal pigment epithelial cells, interphotoreceptor mat

121 lar degeneration, and transplantation of new retinal pigment epithelial cells is an attractive strate

122 Integrity of retinal pigment epithelial cells is necessary for photor

123 Thus, SCD expression in retinal pigment epithelial cells is regulated by retinoi

124 Retinal pigment epithelial cells isolated from dystrophi

125 Thus, in retinal pigment epithelial cell layers, rapamycin decrea

126 ocalized to the ganglion, inner nuclear, and retinal pigment epithelial cell layers.

127 amino acid phenylalanine (Phe) between human retinal pigment epithelial cell line (ARPE-19) and tachy

128 scular endothelial growth factor (VEGF) in a retinal pigment epithelial cell line (ARPE-19) and to de

129 proximal tubular cell line (TEC) and a human retinal pigment epithelial cell line (ARPE-19).

130 Knockdown of Tgifs in a human retinal pigment epithelial cell line also increased EVI5

131 stine-glutamate transporter xc- in the human retinal pigment epithelial cell line ARPE-19 and in reti

132 cludin expression was inhibited in the human retinal pigment epithelial cell line ARPE-19 by siRNA.

133 apability of differentiation in vitro of the retinal pigment epithelial cell line ARPE-19 has been pr

134 glutamate transporter (x(c)(-)) in the human retinal pigment epithelial cell line ARPE-19, clone the

135 We next used the human retinal pigment epithelial cell line RPE-1 as a model sy

136 After introducing a retinal pigment epithelial cell line to the subretinal s

137 amined in the present study, using the human retinal pigment epithelial cell line, ARPE-19.

138 n class III myosin, MYO3A, from retina and a retinal pigment epithelial cell line.

139 ually to cysteine and expressed in the human retinal pigment epithelial cell line.

140 Confluent cultures of a human retinal pigmented epithelial cell line (ARPE-19) were de

141 s) up-regulate the expression of VEGF in the retinal-pigmented epithelial cell line ARPE-19.

142 o address this question we established human retinal pigment epithelial cell lines expressing wild ty

143 Menkes mRNAs in mouse and human retinas and retinal pigment epithelial cell lines.

144 o an understanding of the adverse effects of retinal pigment epithelial cell lipofuscin.

145 Retinal pigment epithelial cell malfunction is a causati

146 dition, in the skate but not the rat retina, retinal pigment epithelial cells may be an alternative s

147 Thus, FasL expressed on retinal pigment epithelial cells may control the growth

148 Phagocytosis of extracellular matrix by retinal pigment epithelial cells may represent a novel m

149 gocytes were blood-borne macrophages and not retinal pigment epithelial cells nor Muller glia.

150 nsport of N5-methyltetrahydrofolate in human retinal pigment epithelial cells occurs exclusively thro

151 fluorescent materials, called lipofuscin, in retinal pigment epithelial cells of the aging retina is

152 embranes (BMs) serve as attachment sites for retinal pigment epithelial cells on Bruch's membrane and

153 Human retinal pigment epithelial cells play a pivotal role in

154 Subconfluent retinal pigment epithelial cells preferentially phagocyt

155 al membranes of CMV-infected polarized human retinal pigment epithelial cells propagated on permeable

156 transformations in photoreceptor (RDH12) and retinal pigment epithelial cells (RDH11).

157 thelial cell line as well as human and mouse retinal pigment epithelial cells resulted in killing of

158 MYC(N) protein levels, and inducing MYCN in retinal pigmented epithelial cells resulted in CHK1 phos

159 Microarray measurements in retinal pigment epithelial cells revealed 36 genes regul

160 r genes caused replication defects in rhesus retinal pigment epithelial cells: Rh01 (an HCMV TRL1 ort

161 The results suggest that in retinal pigment epithelial cells, rod outer segment-spec

162 The retinal pigment epithelial cell (RPE cell) layer protect

163 flammatory activity, it also participates in retinal pigment epithelial cell (RPE) mediated activatio

164 (iPSC), and differentiated these cells into retinal pigment epithelial cells (RPE) to study the mech

165 ctrooculogram light peak (LP), lipofuscin in retinal pigment epithelial cells (RPE), and fluid- and d

166 t epithelium; and primary cultures of bovine retinal pigment epithelial cells (RPE), pericytes (RPC),

167 lateral plasma membrane protein expressed in retinal pigment epithelial cells (RPE).

168 initiator of blue-light-induced apoptosis in retinal pigment epithelial cells (RPE).

169 rocess involving photoreceptors and adjacent retinal pigment epithelial cells (RPE).

170 rough a complex set of reactions in adjacent retinal pigment epithelial cells (RPE).

171 ucose in microvascular endothelial cells and retinal pigment epithelial cells (RPE).

172 essing human skin fibroblasts (BJ-hTERT) and retinal pigment epithelial cells (RPE-hTERT) retain norm

173 expression in mouse retinal cells and human retinal pigmented epithelial cells (RPE) through STAT1-m

174 retinopathy and that smooth muscle cells and retinal pigment epithelial cells secrete HGF in the eye.

175 phogenetic protein-4 may interact to promote retinal pigment epithelial cell senescence and that bone

176 persistent mild oxidative stress can induce retinal pigment epithelial cell senescence through p53-p

177 Retinal pigment epithelial cell signals also changed dra

178 the copolymers were shown to be non-toxic to retinal pigment epithelial cells, studies of drug releas

179 n the culture supernatants of astrocytes and retinal pigment epithelial cells support the CD8 autorea

180 esponses via VEGF receptors expressed on the retinal pigment epithelial cells that drive this disease

181 l cells were induced to undergo apoptosis by retinal pigment epithelial cells through a Fas-FasL inte

182 n activation greatly enhanced the ability of retinal pigment epithelial cells to adhere to tenascin-r

183 Our finding that ngn2 can instruct nonneural retinal pigment epithelial cells to differentiate toward

184 ld be effective in improving the efficacy of retinal pigment epithelial cell transplantation in wet a

185 fects the secretion of angiogenic factors by retinal pigmented epithelial cells under normoxic, hypox

186 how that alphaB is secreted from human adult retinal pigment epithelial cells via microvesicles (exos

187 LEDGF1-326 increased human retinal pigment epithelial cell viability from 48.3 +/-

188 dystrophic Royal College of Surgeons-p+ rat retinal pigment epithelial cells was studied in primary

189 Notably, using polarized adult retinal pigment epithelial cells, we show that the secre

190 Human retinal pigment epithelial cells were cultured on an imp

191 ARPE-19 retinal pigment epithelial cells were depleted of their

192 Human retinal pigment epithelial cells were transfected in vit

193 Human retinal pigment epithelial cells were treated with vario

194 Retinal pigment epithelial cells were visible in patient

195 trally but not in regions with scotomas, and retinal pigment epithelial cells were visible in regions

196 iling dataset obtained on differentiation of retinal pigment epithelial cells where 399 proteins were

197 reactions in photoreceptors and in adjacent retinal pigment epithelial cells where all-trans-retinol

198 inner segments and to the apical surface of retinal pigment epithelial cells where it might be invol

199 neuronal cells, and Muller cells as well as retinal pigment epithelial cells, whereas AdV5-GFP trans

200 escent lipofuscin pigment A2E accumulates in retinal pigment epithelial cells with age and is particu

201 tofluorescent lipofuscin that accumulates in retinal pigment epithelial cells with age may contribute

202 autofluorescent pigments that accumulate in retinal pigment epithelial cells with aging and in some

203 is of A2E, a fluorophore that accumulates in retinal pigment epithelial cells with aging and in some

204 In vitro treatments of human retinal pigment epithelial cells with CEP-dipeptide or C

205 tion were observed in human liver, lens, and retinal pigment epithelial cells with increasing concent

206 c glycolysis, increased after stimulation of retinal pigment epithelial cells with LPS or poly(I:C),

207 Treatment of human retinal pigment epithelial cells with NACA protected aga

208 hypothesis, we altered the GSSG:GSH ratio in retinal pigment epithelial cells with the thiol-specific

209 Alternatively, we find that transduction of retinal pigmented epithelial cells with alpha9 integrin,

210 th muscle actin (SMA) expression in adjacent retinal pigment epithelial cells, with subsequent format