ライフサイエンスコーパス: saccadic

1 These saccadic abnormalities related to DN involvement but wer

2 The saccadic abnormalities related to DN involvement were in

3 pects of oculomotion and delineates specific saccadic abnormalities that could be used to detect the

4 brain, both for perceptual decisions and for saccadic actions during visual search.

5 a sophisticated deployment of eye movements (saccadic actions) to gather information to subserve perc

6 oscillatory activity in the hippocampus and saccadic activity in monkeys performing a recognition me

7 e essential for memory, is modulated by this saccadic activity, but the relationship between visual e

8 ction of stimulus-driven activity, increased saccadic activity, or enhanced representation of the opp

9 We observed that (1) saccadic adaptation can be induced by modifying target o

10 aze recalibration, similar to the well-known saccadic adaptation effect [9-11].

11 Such saccadic adaptation is usually induced by systematically

12 These results demonstrate that saccadic adaptation occurs even when the stimulus is alr

13 nguish between these alternatives, we used a saccadic adaptation paradigm to dissociate the location

14 In a typical short-term saccadic adaptation protocol, the target moves intrasacc

15 We used a miniaturized version of saccadic adaptation, an experimental procedure by which

16 from studies of vestibulo-ocular reflex and saccadic adaptation, we conclude that the plasticity at

17 sus monkeys during both backward and forward saccadic adaptation.

18 e remapped during either forward or backward saccadic adaptation.

19 m is considered to be critically involved in saccadic adaptation.

20 that cerebellar excitability is critical for saccadic adaptation.

21 ement active competition for attentional and saccadic allocation, but such suppressive interactions h

22 ipants were shorter in duration, and smaller saccadic amplitudes were observed only for the RP partic

23 found these were differentially accessed by saccadic and optokinetic inputs.

24 Both saccadic and perceptual report reaction times changed in

25 lds of the visual mechanisms responsible for saccadic and perceptual responses during the same visual

26 es of LIP neurons in two subjects with their saccadic behavior and three estimates of stimulus value.

27 put, and use these changing beliefs to guide saccadic behavior in ways consistent with principles of

28 ts to that of macaques, and found that their saccadic behavior is comparable across a number of sacca

29 on saccadic function, the quality of reading saccadic behavior is maintained with good reading abilit

30 In contrast, saccadic behavior when reading (forward and regressive s

31 otor nerves or nuclei, vertical supranuclear saccadic centres, and convergence neurons.

32 ntal eye field (FEF) of monkeys performing a saccadic choice task and simulated the effects using a p

33 transformation of motion information into a saccadic choice.

34 that, contrary to expectations, during rapid saccadic choices perceptual information may directly mod

35 ver, the computational principles underlying saccadic choices remain poorly understood.

36 neurons further revealed that the brainstem saccadic circuitry controls these minute disconjugate sh

37 The proposed saccadic circuitry establishes a complete model of sacca

38 This saccadic continuum extended to nonrestrictive, ecologica

39 model of oculomotor behavior can explain the saccadic continuum from exploration to fixation, for ima

40 rker panel (neuropsychological, stop signal, saccadic control, and auditory stimulation paradigms) ch

41 untermanding stimuli, such as those in large saccadic countermanding tasks: they cancel an upcoming m

42 dback, this information was provided by each saccadic decision threshold, which represented the total

43 By fitting an accumulator model of saccadic decision-making, we show that the inhibitory ef

44 However, saccadic decisions are often studied in isolation, which

45 fine-grained temporal analysis of human peri-saccadic detection performance in an attention task, we

46 Under more natural conditions, trans-saccadic displacement detection is as good as in fixatio

47 We used a novel saccadic distraction task to quantify the speed and accu

48 ce for CD in primates comes largely from the saccadic double-step task, which requires participants t

49 salience and value information influence the saccadic end point within an object, but with different

50 porally dissociate the visual epoch from the saccadic epoch through a delay epoch, and used the local

51 to control for the direct effects of TDCS on saccadic execution.

52 The primary endpoint was horizontal saccadic eye movement (HSEM) velocity, based on its corr

53 Using the saccadic eye movement as a probe, we provide results tha

54 perficial SC, suggesting a novel pathway for saccadic eye movement choice.

55 hat SC buildup neuronal activity signals the saccadic eye movement decision.

56 ave shown that binocular coordination during saccadic eye movement is affected in humans with large s

57 Every saccadic eye movement that we make changes the image of

58 rom baseline to months 12 and 24 in vertical saccadic eye movement velocity as determined by the peak

59 ficant between-group differences in vertical saccadic eye movement velocity or in the other neurologi

60 inaccurately represent eye position during a saccadic eye movement, and to be too slow to support a r

61 (TMS) to any part of the human head during a saccadic eye movement, the ongoing eye velocity was redu

62 osition of gaze, the hand, and the goal of a saccadic eye movement.

63 targets even when they are not the goal of a saccadic eye movement.

64 Saccadic eye movements "bring" eccentric targets to the

65 olation by performing combined recordings of saccadic eye movements and fast event-related fMRI durin

66 We consider saccadic eye movements and hypothesize that duration of

67 nts, beyond its traditional roles in guiding saccadic eye movements and localizing attention.

68 This study predicts that saccadic eye movements and normal head movements after v

69 implicated as a salience map for control of saccadic eye movements and visual attention.

70 here sensorimotor transformations leading to saccadic eye movements are implemented in the brain, les

71 The frequency of these saccadic eye movements belies the complexity underlying

72 elp gate the transition between fixation and saccadic eye movements by monosynaptically suppressing a

73 nt contributions to our understanding of how saccadic eye movements can be rapidly inhibited, changed

74 When saccadic eye movements consistently fail to land on the

75 Saccadic eye movements direct the high-resolution foveae

76 Saccadic eye movements facilitate rapid and efficient ex

77 Participants were asked to make saccadic eye movements for different monetary rewards, w

78 This study examines the consequences of saccadic eye movements for the internal representation o

79 participants to make two visually triggered saccadic eye movements in brief succession.

80 and execution of visually guided manual and saccadic eye movements in macaque monkeys.

81 A key structure for directing saccadic eye movements is the superior colliculus (SC).

82 l stimuli in the contralateral field and for saccadic eye movements made to those stimuli.

83 However, the amplitude of saccadic eye movements made to visual targets can be sys

84 This study aims to determine whether the saccadic eye movements of people with glaucoma differ fr

85 Saccadic eye movements play a central role in primate vi

86 Saccadic eye movements provide a valuable model to study

87 Adaptation of saccadic eye movements provides an excellent motor learn

88 During visual exploration, saccadic eye movements scan the scene for objects of int

89 Our studies show mice make saccadic eye movements spontaneously and in response to

90 he monkeys to occasionally withhold planned, saccadic eye movements to a visual target.

91 Animals can make saccadic eye movements to intercept a moving object at t

92 s and other animals with foveate vision make saccadic eye movements to prioritize the visual analysis

93 We understand the world by making saccadic eye movements to various objects.

94 Humans perform saccadic eye movements two to three times per second.

95 ll amplitude, nasally directed (ipsiversive) saccadic eye movements were evoked by microstimulation i

96 r to the anterior frontal sulcus, from which saccadic eye movements were evoked with electrical stimu

97 ked by SC stimulation as well as spontaneous saccadic eye movements were larger in the dark-reared mi

98 Saccadic eye movements were measured using infra-red ocu

99 ectrical microstimulation to the SC, so that saccadic eye movements were not evoked.

100 icant increase in the probability of evoking saccadic eye movements when low current electrical stimu

101 to recall the sequence and reproduce it with saccadic eye movements when presented with an array of o

102 We explore the visual world through saccadic eye movements, but saccades also present a chal

103 erience the visual world through a series of saccadic eye movements, each one shifting our gaze to br

104 holds are elevated before, during, and after saccadic eye movements, is an important mechanism for ma

105 In monkeys deciding between alternative saccadic eye movements, lateral intraparietal (LIP) neur

106 During saccadic eye movements, the job of the nervous system is

107 s may not be directly involved in triggering saccadic eye movements, they are nonetheless highly sacc

108 During the preparation of saccadic eye movements, visual attention is confined to

109 tes learning of image statistics and directs saccadic eye movements, we propose that the acquisition

110 We examined whether the preparation of saccadic eye movements, when behaviorally dissociated fr

111 esponse field (RF) stimuli are targeted with saccadic eye movements.

112 t of the BG-brainstem projection controlling saccadic eye movements.

113 explore the visual world through the use of saccadic eye movements.

114 ial functions, such as spatial attention and saccadic eye movements.

115 retina and serially sample visual scenes by saccadic eye movements.

116 visuospatial attention may be linked through saccadic eye movements.

117 atable behavioral deficits in the metrics of saccadic eye movements.

118 of visual targets flashed around the time of saccadic eye movements.

119 flects the planning of behaviorally relevant saccadic eye movements.

120 brain forms decisions comes from studies of saccadic eye movements.

121 of structures involved in the programming of saccadic eye movements.

122 nd specifying the amplitude and direction of saccadic eye movements.

123 ons that are directly involved in triggering saccadic eye movements.

124 of spatial attention, even in the absence of saccadic eye movements.

125 o not see the visual motion generated by our saccadic eye movements.

126 in the transformation of visual signals into saccadic eye movements.

127 r on object recognition) to the precision of saccadic eye movements.

128 a V4 of nonhuman primates trained to execute saccadic eye movements.

129 onkeys that is triggered by the execution of saccadic eye movements.

130 ld as stable, although we constantly perform saccadic eye movements?

131 Here, human participants used saccadic-eye and hand-pointing movements to report recog

132 at fatigue can affect the characteristics of saccadic (fast ballistic) eye movements in nonsurgical s

133 is; psychomotor functioning (using the Wayne Saccadic Fixator (WSF)); and adverse events.

134 Environment and dual-task impacted on saccadic frequency especially for PD.

135 For both groups, saccadic frequency increased when approaching a turn com

136 Increased saccadic frequency was related to poorer attention, cogn

137 Visual sampling (saccadic frequency) and gait were measured concurrently

138 Despite the limitations on saccadic function, the quality of reading saccadic behav

139 during nonadaptation sessions did not affect saccadic gain, velocity, or duration, demonstrating that

140 oculomotor profile (e.g. exacerbation of the saccadic gap/overlap effect, preserved saccadic velocity

141 and 26 healthy control subjects completed a saccadic Go/No-Go task with a head-mounted infrared sacc

142 is not contingent on prior selection of the saccadic goal by visually driven FEF responses.

143 Avian saccadic head/eye movements have been shown to vary cons

144 ovement testing, family members demonstrated saccadic hypometria, reduced steady-state pursuit gain,

145 These results support the hypothesis that saccadic indices reflect graded changes in fatigue.

146 Blinks effectively remove saccadic inhibition and prematurely trigger impending sa

147 ere we show that a behavioral effect called "saccadic inhibition" (1) is predicted by existing comple

148 us FEF alpha-band power predicted successful saccadic inhibition.

149 their retinotopic location in time for post-saccadic input, validating dynamic predictive coding the

150 lly generally were most persistent following saccadic input, whereas cells located rostrally were mos

151 During normal saccadic inspection of natural images, the receptive fie

152 frequently interrupted by microsaccades and saccadic intrusions (SI).

153 mpted fixation; fixational eye movements and saccadic intrusions (SIs) continuously change the positi

154 with posterior cortical atrophy showed large saccadic intrusions whose frequency correlated significa

155 Older subjects had significantly increased saccadic latencies (at all locations; P < 0.05), decreas

156 such as Huntington disease produce increased saccadic latencies and impaired suppression of saccades

157 Saccadic latencies are influenced by what occurred durin

158 The model decomposes saccadic latencies into parameters for the decision proc

159 We used a saccadometer to measure the saccadic latencies of 9 DBS patients (1) preoperatively,

160 The ALS group also showed reduced saccadic latencies that correlated with increased activa

161 s underlying disinhibition, using horizontal saccadic latencies that obviate the impact of limb slown

162 plans a saccade knock out a subpopulation of saccadic latencies that would otherwise occur, producing

163 Mean saccadic latencies were similar between all three groups

164 Saccadic latency and accuracy are related to visual thre

165 related to visual threshold, suggesting that saccadic latency and accuracy could be useful as perimet

166 Good reliability of saccadic latency and percentage of errors in both antisa

167 Since this saccadic latency can be rapidly and objectively measured

168 Saccadic latency increased as stimulus size decreased in

169 stimulator is turned on, but in the case of saccadic latency the pattern is different: surgery produ

170 we evaluated for group-level differences in saccadic latency, accuracy, and visual threshold at each

171 han or equal to 10% in all six EOMS even for saccadic loading rates.

172 sponses to predicted stimuli at the new post-saccadic location in V1.

173 ant signal for saccadic system and its trans-saccadic manipulation entails considerable changes at mu

174 y was to evaluate test-retest reliability of saccadic measures in prediagnostic carriers of the HD ge

175 complex interplay between visual and central saccadic mechanisms during reading.

176 ced by time-on-duty (~24 hours) might affect saccadic metrics in surgical residents.

177 Saccadic mislocalization, by contrast, is robust and res

178 s were distinct from the neurons' visual and saccadic modulations and from signals of expected reward

179 Therefore, a TMS pulse centrally perturbs saccadic motor commands, which are monitored possibly vi

180 humans, flies generate both smooth and rapid saccadic movements to stabilize their gaze.

181 timulus relevant information; and (2) that a saccadic neural marker for a saccade target stimulus cou

182 Here we show how premotor saccadic neurons control these small fixational eye move

183 pendence we quantify and its link with trans-saccadic object perception instead suggest that feature

184 t converts time-varying retinal signals into saccadic oculomotor commands.

185 y at saccadic onset and an enhancement after saccadic offset.

186 the retina that is generated by a saccade as saccadic omission [1]: the visual stimulus generated by

187 results show that a stimulus that undergoes saccadic omission can nevertheless generate a shape cont

188 In the laboratory, saccadic omission is often studied by investigating sacc

189 the motion created by our own eye movements-saccadic omission.

190 uce a suppression of contrast sensitivity at saccadic onset and an enhancement after saccadic offset.

191 it is crucial that saccadic suppression and saccadic onset be temporally synchronous.

192 sion was measured between -50 and 50 ms from saccadic onset.

193 d throughout the oculomotor integrator after saccadic or optokinetic stimulation.

194 Practice on peri-saccadic orientation discrimination led to long-lasting

195 We describe a new familial disorder--'micro-saccadic oscillations and limb tremor (microSOLT)'--in a

196 ernal inhibition (in this case glycinergic), saccadic oscillations and limb tremor were reproduced.

197 OLT)'--in a mother and daughter who had tiny saccadic oscillations of the eyes and tremor of the hand

198 We also explored associations between saccadic outcomes and clinical measures.

199 me (8), INO (20), one and half syndrome (3), saccadic palsy (28), and smooth pursuit palsy (46).

200 The saccadic palsy either improved during the early part of

201 Vergence may also enable gaze shifts in saccadic palsy.

202 te the contribution of other areas, abnormal saccadic parameters were compared with global and region

203 ion between motivation level and rewards for saccadic peak velocity (F2,18=5.153, p=0.049), with the

204 ts on medication demonstrated an increase in saccadic peak velocity as reward magnitude increased (an

205 nergic drugs, both in pupillary response and saccadic peak velocity response to reward.

206 group exhibiting less reward sensitivity in saccadic peak velocity.

207 red if this could also be the case with peri-saccadic perception.

208 atrophy, and highlights multiple aspects of saccadic performance which distinguish posterior cortica

209 and typical Alzheimer's disease were seen in saccadic performance.

210 In a saccadic planning task, we observed that distinct behavi

211 al information may directly modulate ongoing saccadic plans, and this process is not contingent on pr

212 ate that crowding, spatial localization, and saccadic precision show clear dissociations, indicative

213 Therefore, pre-saccadic predictions update their retinotopic location i

214 The results show that saccadic preparation and visual sensitivity oscillations

215 The results show that saccadic preparation and visual sensitivity oscillations

216 Spatial attention and saccadic processing therefore co-ordinate well to ensure

217 Other saccadic properties varied as function of image size as

218 s, whereas Wilson disease is associated with saccadic pursuits, increased antisaccade latencies and d

219 Saccadic rates during exploration are higher than those

220 s in SC activity to concomitant increases in saccadic reaction time (SRT).

221 Primary outcome measures included average saccadic reaction time in a visually guided saccade proc

222 but overlapping with target onset shortened saccadic reaction times (RTs) for ipsiversive (to the st

223 n cell types, including signals that predict saccadic reaction times and CS-dependent changes in syst

224 ive control and sustained attention, reduced saccadic reaction times, and reduced latencies to diseng

225 in 8Av (close to FEF) shortened or prolonged saccadic reaction times, depending on the task-instructe

226 ioral effect of microsaccadic suppression on saccadic reaction times, even for continuously presented

227 onal weighting of saccade targets as well as saccadic reaction times.

228 enous cue was biased towards the cue for the saccadic response mode only, suggesting that the degree

229 Saccadic response speeds were used to estimate the param

230 ayesian model fitted to individual trialwise saccadic response speeds.

231 indexed motivation level using pupillary and saccadic response to monetary incentives, allowing rewar

232 th the time needed to initiate the voluntary saccadic response, changed steadily as training progress

233 human visual system in the absence of overt saccadic responses (including in V1).

234 We show that visual and pre-saccadic responses of frontal eye field (FEF) neurons ar

235 nterpret the reduced FEF activity and slower saccadic responses to reflect inhibitory influences on t

236 dity varied in time and the targets required saccadic responses.

237 tivated during inhibition of both manual and saccadic responses.

238 However, saccadic sampling has largely been explored in paradigms

239 logic eye oscillations while allowing normal saccadic shifts of gaze.

240 ll known that the medial cerebellum controls saccadic speed and accuracy.

241 to be related to the problem of maintaining saccadic stability.

242 the action of special mechanisms conferring saccadic stability.

243 on experiment: the Wheeless task, in which a saccadic stimulus is followed after a short delay by a s

244 components when they commit errors during a saccadic stop-signal task.

245 ted by the eye movements, it is crucial that saccadic suppression and saccadic onset be temporally sy

246 ide a quantitative description of behavioral saccadic suppression and thereby allow a more focused se

247 The brain might accomplish saccadic suppression by reducing the gain of visual resp

248 t the most parsimonious mechanism underlying saccadic suppression is a stimulus-independent reduction

249 This saccadic suppression is thought to be a mechanism for ma

250 jects remain stable or move, which is called saccadic suppression of displacement (SSD).

251 lacement thresholds usually observed in the "saccadic suppression of displacement" paradigm are a res

252 We suggest that saccadic suppression originates from efficient sensorimo

253 ual stability requires that a mechanism like saccadic suppression removes perisaccadic stimuli from v

254 This pattern of results suggests that saccadic suppression shares some of the circuitry respon

255 These results suggest that saccadic suppression shares the brain circuits responsib

256 Strong saccadic suppression was measured between -50 and 50 ms

257 Saccadic suppression, a behavioral phenomenon in which p

258 ion cells, like temporal-frequency doubling, saccadic suppression, and contrast adaptation.

259 es in attention, visual image stability, and saccadic suppression, but in contrast to feedforward pat

260 modulations found in the SC: they exhibited saccadic suppression, the inhibition of activity at the

261 One clear case is saccadic suppression, the reduced visibility around the

262 c omission is often studied by investigating saccadic suppression, the reduction in visual sensitivit

263 e answer in part is a brain mechanism called saccadic suppression, which reduces the responses of vis

264 This laboratory phenomenon--behavioral saccadic suppression--is thought to underlie the everyda

265 between three mechanisms that could underlie saccadic suppression.

266 s suggest that size is a relevant signal for saccadic system and its trans-saccadic manipulation enta

267 uss the "predictive" properties of the visuo-saccadic system and the nature of this location where th

268 olliculus (SC), but they also disinhibit the saccadic system by removing the potent inhibition of pon

269 We removed downstream inhibition on the saccadic system using the trigeminal blink reflex, trigg

270 ystem designed to move the eyes rapidly, the saccadic system, may play a role.

271 us to translate the interpretations from the saccadic systems to the limb movement system.

272 pression was absent when the features of the saccadic target matched the features preferred by indivi

273 ediated frontal eye field activity increased saccadic target selection but the D2 receptor manipulati

274 key's ability to adapt saccade size to intra-saccadic target steps that produced a consistent saccade

275 ision formation emerged from studies where a saccadic target was always stimulating the RF during dec

276 cause compression of visual space around the saccadic target, and also a compression of time, both ph

277 orientation of both the RF stimulus and the saccadic target.

278 n of saccades depends on the features of the saccadic target.

279 control area massively converge towards the saccadic target.

280 saccades and less about the features of the saccadic target.

281 the briefly presented stimulus closer to the saccadic target.

282 orizontal saccades at will to two stationary saccadic targets separated by 20 degrees .

283 Time to reach saccadic targets was significantly associated with parie

284 ubject by their performance in a simple step saccadic task, which identifies the two free parameters

285 Despite using currents well above saccadic thresholds of the directly adjacent Frontal Eye

286 e another; (4) the FM subsystem superimposes saccadic turns upon smooth pursuit; and (5) the two syst

287 preted as indicating that LIP neurons encode saccadic value and that they mediate value-based decisio

288 traparietal cortex encode a relative form of saccadic value, explicitly dependent on the values of th

289 rd temporal discount function and changes in saccadic velocity and duration.

290 Time-on-duty decreased saccadic velocity and increased subjective fatigue but d

291 These findings demonstrate that saccadic velocity and pupil diameter are affected by rew

292 Saccadic velocity and pupil modulation by reward were us

293 voluntary control, a fatigue index based on saccadic velocity has the potential to provide an accura

294 Our data show, for the first time, that saccadic velocity is a reliable indicator of the subject

295 Because saccadic velocity is not under voluntary control, a fati

296 f the saccadic gap/overlap effect, preserved saccadic velocity) reflects weak input from degraded occ

297 We found that in humans, saccadic vigor, assessed using velocity as a function of

298 al system has adapted to compensate for peri-saccadic vision changes.

299 Peri-saccadic vision is also characterized by a mislocalizati

300 mmonly viewed as obligatory elements of peri-saccadic vision.