ライフサイエンスコーパス: sad

1 Finally, of the 24 sad mutants analysed in this study, only three had defec

2 g the following: mental health conditions; a sad or depressed mood; substance abuse problems; medical

3 ng while they alternated between recalling a sad, ruminative thought about their loved one (grief sta

4 ("Al") Gilman, M.D., Ph.D., represents a sad signpost for an era spanning over 40 years in molecu

5 rent common facial expressions: the smile, a sad expression and an expression of horror, and three co

6 The wild-type allele, sad-1(+), encodes a putative RNA-directed RNA polymerase

7 feeling confused (43% vs. 22%, p = .004) and sad (46% vs. 31%, p = .04) and less likely to report bei

8 (happy, surprise, fear, disgust, anger, and sad) using the same facial movements by virtue of their

9 bidirectional frontotemporal connections and sad faces modulating unidirectional fusiform-orbitofront

10 Expression of dib and sad continues to be localized in this endocrine compartm

11 Unlike dib and sad, shd is not expressed in the ring gland but is expre

12 When cells are transfected with both dib and sad, they metabolize the [3H]ketotriol to [3H]E in high

13 ched videos depicting cocaine, gambling, and sad scenarios to investigate the neural correlates of cr

14 isation severity consisted in both happy and sad conditions of the anterior ventral precuneus (BA7),

15 esented with facial expressions of happy and sad emotion at three intensity levels (0%-50%-100%) in a

16 erior cingulate difference between happy and sad emotion regulation.

17 ective connectivity in response to happy and sad face emotions, despite normal activations within eac

18 changes in amygdalar responses to happy and sad faces and improved processing of positive stimuli du

19 The opposite was observed for happy and sad faces, where greater thalamic and midfrontal activat

20 We created second-order faces with happy and sad facial expressions specified solely by local directi

21 position, I discuss the effects of happy and sad moods on discourse and sentence comprehension.

22 and we compare people with induced happy and sad moods.

23 nts, gambling videos in PG participants, and sad videos in control participants.

24 encoding an RNA-directed RNA polymerase, and sad-2, encoding a protein that controls the perinuclear

25 nted infrequently as attentional targets and sad and neutral pictures as novel distractors.

26 On each treatment, brain responses to angry, sad, and neutral faces were measured with functional mag

27 , tired, short of breath, restless, anxious, sad, hungry, scared, thirsty, confused).

28 subjects more frequently perceived faces as sad.

29 g with posterior cingulate gyrus (PCC, BA23, sad condition) and anteromedial thalamus (happy conditio

30 In every medical specialty bad, sad, and difficult information must be given to patients

31 of two marker genes for lipid biosynthesis (sad and ear) occurred at a bud length of 2-3 mm, and the

32 mporal brain network, whereas mood congruent sad information was associated with less network modulat

33 are designated surface attachment defective (sad ).

34 which we term surface attachment defective (sad).

35 The resulting substrate adhesion-deficient (sad) mutants grew in plastic dishes without attaching to

36 hree members of the stearoyl-ACP desaturase (sad) gene family by Northern blotting, in situ hybridiza

37 d anterior (p(FWE) = 0.041) cingulate during sad face emotion processing.

38 and reduced top-down cortical control during sad emotion processing.

39 tivity in left inferior frontal gyrus during sad face inhibition, demonstrating bipolar trait effects

40 Inactivation of either sad-1 or sad-2 suppresses MSUD.

41 y in response to emotionally valenced faces (sad, fearful, angry, happy, neutral) following a negativ

42 pants inhibited the response to happy faces, sad faces, or letters.

43 they viewed a two-by-two matrix of fearful, sad, happy, and neutral facial expressions before they w

44 ociated with increases in reports of feeling sad (P < .001) or angry (P = .01).

45 Fathers also reported feeling sad, hurt, or angry when providers were nonchalant and i

46 Only 22/131 (16%) fathers reported feeling sad, hurt, or angry.

47 ideotapes designed to elicit happy feelings, sad feelings, or the desire to use cocaine.

48 m caspase inhibitor Z-Val-Ala-Asp (ome)-FMK (sad) was given, and cardiac function was determined in i

49 ation time and longer mean fixation time for sad faces predicted higher depressive symptom scores.

50 A functional sad-2(+) gene is necessary for SAD-1 localization, but t

51 maximal expression of the lipid marker genes sad, ear, acp and cyb5 was at the 3-5 mm bud stages, wit

52 me of the research on the impact that giving sad, bad, and difficult news has on doctors and patients

53 to 5 target emotions: angry, anxious, happy, sad, and neutral.

54 tially in the four target conditions (happy, sad, angry and fearful) along the dimension of threat-re

55 uring implicit processing of emerging happy, sad, fearful and angry faces and shapes.

56 ects viewed images designed to induce happy, sad, and neutral emotional states.

57 ciated with correct identification of happy, sad, angry and fearful faces.

58 ented mild and extreme intensities of happy, sad, angry, fearful, disgusted, and neutral faces, balan

59 d with neutral faces (event related): happy, sad, anger, and fear.

60 d comparison among neural response to happy, sad, and neutral words, in the context of these words as

61 In sad-1 mutant animals presynaptic vesicle clusters in sen

62 Sensory axons fail to terminate in sad-1 mutants, whereas overexpression of SAD-1 causes se

63 groups had a greater response to inhibiting sad faces in emotion processing and regulation regions,

64 al states: happy, tender, afraid, irritated, sad, and no emotion.

65 g masked happy faces but decreased to masked sad faces in the experimental versus control group follo

66 reater amygdala responses than HCs to masked sad faces, whereas HCs showed greater amygdala responses

67 While viewing both masked-sad and masked-happy faces relative to masked-neutral fa

68 wed distinct hemodynamic responses to masked-sad and masked-happy faces in neural circuits known to s

69 r BOLD responses than the controls to masked-sad versus masked-happy faces in the hippocampus, amygda

70 d the impact of experimentally induced mood (sad, neutral) on plasma IL-18 and relationships with con

71 Moreover, sad vocalizations modulated the activity of brain region

72 angry vs. neutral and angry vs. sad but not sad vs. neutral faces.

73 emotional responses to stimuli that were not sad.

74 Two classes of sad mutants were analysed: (i) mutants defective in flag

75 The expression of sad and dib is concentrated within the individual segmen

76 We found that increasing intensity of sad facial expression was associated with enhanced activ

77 n also resulted in higher arousal ratings of sad stimuli.

78 s of sociability and enhanced recognition of sad facial expressions.

79 Transcripts of sad-1(+) can be detected during the sexual phase in a ho

80 th BD performed worse than those with MDD on sad emotion regulation but normal on happy emotion regul

81 Inactivation of either sad-1 or sad-2 suppresses MSUD.

82 ubjective responses to the happy (P =.56) or sad (P =.81) videotapes.

83 tapes but not in patients watching happy or sad tapes or in healthy subjects under any condition.

84 ideotaped scenarios with gambling, happy, or sad content.

85 l neural response to emotional, particularly sad, distractors in the lateral orbitofrontal cortex.

86 the amygdala toward face stimuli portraying sad expressions that is evident even when such stimuli a

87 red for MSUD have been described previously: sad-1 (suppressor of ascus dominance), encoding an RNA-d

88 ated a second gene involved in this process, sad-2.

89 ence than in late childhood while processing sad and happy versus neutral faces.

90 Patients with MDD regulated sad and happy emotions poorly compared with those with B

91 those seen in disembodied (dib) and shadow (sad) mutants, two other genes of the Halloween class tha

92 yonic lethals, disembodied (dib) and shadow (sad), code for mitochondrial cytochromes P450 that media

93 onal MRI as they viewed face stimuli showing sad, happy or neutral face expressions, presented using

94 sicle proteins to dendrites, suggesting that sad-1 affects axonal-dendritic polarity as well as synap

95 rugator and depressor anguli oris during the sad look and the frontalis and mentalis during the horro

96 rugator and depressor anguli oris during the sad look, the frontalis and mentalis during the horror l

97 mood on a visual analog scale following the sad mood induction procedure (MIP).

98 Critical care professionals know the sad reality behind the statistical scarcity of organ sup

99 activity were observed during viewing of the sad and happy scenarios, they were distinct from those c

100 Molecular analysis of the sad mutants revealed that the ClpP protein (a component

101 Amygdala hyper-reactivity to sad emotion is involved in a specific non-response to a

102 hether the amygdala has a neural response to sad and/or angry facial expressions.

103 d activity in parietal cortex in response to sad faces but no differences in brain activity in a prio

104 Aberrant amygdala activation in response to sad facial emotions is specific to the depressed state a

105 neural substrates which mediate responses to sad and angry expressions.

106 assessment predicted increased responses to sad faces in amygdala, hippocampal, parietal, and orbita

107 abolished the abnormal amygdala responses to sad faces in currently depressed patients but did not al

108 essing biases occur in amygdala responses to sad faces presented below the level of conscious awarene

109 sed bilateral amygdala responses specific to sad faces relative to healthy comparison subjects and no

110 tients showed elevated responses specific to sad targets in rostral anterior cingulate extending to a

111 sponse to attentional targets rather than to sad distractors.

112 The bias toward sad faces also was evident in rMDD participants relative

113 eers were studied before and after transient sad mood challenge.

114 Compared with viewing sad and amusing films, the episodes were associated with

115 In healthy volunteers, sad faces modulated bi-directional connections between a

116 MDD and BD differed with regard to happy vs sad emotion regulation (t = 4.19; P < .001; Cohen d = 1.

117 n processing angry vs. neutral and angry vs. sad but not sad vs. neutral faces.

118 e active in healthy subjects when they watch sad tapes than when they watch happy tapes, suggesting a

119 elicited under standard conditions (watching sad and amusing emotional films, being startled); and (i

120 ormal in cocaine-dependent subjects watching sad tapes, suggesting more general affective dysregulati

121 he web at http://abagyan.scripps.edu/lab/web/sad/show.cgi or by using MySQL, and is also available to

122 When sad (CYP315A1) is transfected into Drosophila S2 cells,

123 ctivity while regulating happy compared with sad emotions.

124 with the birth of your child?" and "Are you sad, hurt or angry today about something personnel did i