ライフサイエンスコーパス: safe

1 s into two categories of less safe and least safe.

2 immune-stimulation of pathogens, while being safe.

3 rocessing and digestion process, and totally safe.

4 TATION: PfSPZ Vaccine was well tolerated and safe.

5 Transendocardial CD133(+) cell therapy was safe.

6 i-CD47, blood parameters remained normal and safe.

7 ection and antiviral use, and appeared to be safe.

8 ion of unsafe abortion and WHO guidelines on safe abortion to categorise abortions as safe or unsafe

9 in developing countries, to ensure access to safe abortion.

10 procedure to be safe, it is unclear whether safe adaptation of this approach from open colectomy (OC

11 An estimated 5 billion people lack access to safe, affordable surgical care and anesthesia when neede

12 Notably, CHCl3 is a convenient and safe alternation of CO gas, provides milder reaction con

13 the outcomes of this operation, making it a safe alternative to orthotopic liver transplantation for

14 bed sono-membrane rupture therapy could be a safe alternative to the currently used high-energy tissu

15 iability in the NMBA panels used to identify safe alternatives.

16 , busulfan, and melphalan is a comparatively safe and active regimen for ASCT in patients with refrac

17 bal guidelines provided to countries for the safe and appropriate disposal of tOPV.

18 Peanut EPIT administration was safe and associated with a modest treatment response aft

19 CD30.CAR-Ts are safe and can lead to clinical responses in patients with

20 eatment with a recombinant food allergen was safe and clinically effective, as determined by using st

21 ith the use of iOCT can be performed in more safe and controlled manner and has to be considered to r

22 ata, so is uncertain, but it provides cheap, safe and direct evidence relating to pandemic emergence,

23 for LHON at low and medium doses seems to be safe and does not damage the temporal retinal nerve fibe

24 me-day discharge (SDD) after appendectomy is safe and does not result in higher-than-expected hospita

25 Photoantimicrobial therapy is safe and easy to implement and, unlike conventional agen

26 A standard rapid desensitization protocol is safe and effective across a broad spectrum of patients,

27 ns urgent medical need for a vaccine that is safe and effective against all four dengue virus serotyp

28 Melody TPVR in Contegra conduits is safe and effective and can be performed in a wide range

29 eeks after standard influenza vaccination is safe and effective and induces an increased antibody res

30 s, we provide evidence that the treatment is safe and effective and, based on absence of peripheral i

31 sults demonstrate the potential of DMDD as a safe and effective antitumor agent in the treatment of l

32 This safe and effective approach expands treatment options an

33 these vaccine vector platforms may present a safe and effective approach to prevent alphavirus-induce

34 We sought to ascertain whether BVS are as safe and effective as drug-eluting stents within 2 years

35 The herein described THV is safe and effective at 30 days with low mortality, signif

36 at the rLS/AMPV-C F&G recombinant virus is a safe and effective bivalent vaccine candidate and that t

37 e for addressing the challenge of developing safe and effective cancer screening tests.

38 ivity to PARP inhibition and could provide a safe and effective combination strategy to selectively t

39 ivery (the so-called artificial pancreas) is safe and effective compared with standard subcutaneous i

40 ise regularly, including glucose targets for safe and effective exercise, and nutritional and insulin

41 er this class of potential therapies will be safe and effective for individuals with retinal diseases

42 The described regimen appears to be safe and effective for patients after renal transplant a

43 nd grazoprevir, with or without ribavirin is safe and effective for patients with HCV genotype 1 or 4

44 Conclusion In-bore 3-T MR-guided biopsy is safe and effective for prostate cancer diagnosis when st

45 ansplantation (HCT) has now been shown to be safe and effective for selected HIV-infected patients wi

46 that advanced practice providers can render safe and effective ICU care.

47 ve BP lowering in patients with acute ICH is safe and effective in improving clinical outcomes.

48 ncomitance with chemotherapy was shown to be safe and effective in influencing remission of aggressiv

49 ies have suggested that stem-cell therapy is safe and effective in patients with liver cirrhosis, but

50 agonists of apelin receptor were shown to be safe and effective in reducing tumour expansion and leng

51 Inpatient penicillin allergy testing is safe and effective in ruling out penicillin allergy.

52 Allo-HSCT is safe and effective in young adult patients with severe P

53 ggest a novel approach to the development of safe and effective live attenuated vaccines directed aga

54 suggests that abortifacients may be good for safe and effective metastatic chemoprevention targeting

55 This inexpensive pig eye model provides a safe and effective microsurgical training model and allo

56 Developing safe and effective nanosystems to deliver active and the

57 FN-gamma signaling in keratinocytes could be safe and effective new treatments, and skin expression o

58 PRETATION: Dual lead thalamic DBS might be a safe and effective option for improving severe, refracto

59 nclusion Conventional and partial UFE may be safe and effective outpatient procedures for women with

60 protein corona, aiding in the development of safe and effective particle-based therapies.

61 in the CLEAR III study and IVF represents a safe and effective strategy to hasten clot resolution th

62 usion:(90)Y radioembolization can serve as a safe and effective treatment for advanced-stage HCC pati

63 The evidence reviewed supports DMEK as a safe and effective treatment for endothelial failure.

64 gene to hematopoietic stem cells have led to safe and effective treatments for several PIDs, includin

65 Research is needed to develop safe and effective treatments, a preventive or therapeut

66 ytherapy (67.5-81 Gy at tumor apex) provides safe and effective tumor control for juxtapapillary chor

67 Designing a safe and effective vaccine requires significant caution

68 igh case fatality, and the availability of a safe and effective vaccine, urgent consideration is need

69 V) epidemic has created an urgent need for a safe and effective vaccine.

70 The development of a safe and effective ZIKV vaccine is therefore an urgent g

71 human clinical trials have proven ASOs both safe and effective.

72 nce initiated, both medications were equally safe and effective.

73 defect with the AMPLATZER Septal Occluder is safe and effective.

74 aphragm pacing with a temporary catheter was safe and effectively contributed to ventilation in conju

75 Thus, here we demonstrate safe and efficacious in vivo catalytic activity of a Pd

76 t computerized cognitive training (CCT) is a safe and efficacious intervention for cognition in older

77 promising RSV vaccine candidate.IMPORTANCE A safe and efficacious respiratory syncytial virus (RSV) v

78 Creation of a safe and efficacious vaccine against Ebola virus (EBOV)

79 to hypofractionated radiotherapy seems to be safe and efficacious without impairing quality of life f

80 Safe and efficient delivery of messenger RNAs for protei

81 The greatest challenge is the safe and efficient delivery of the CRISPR-Cas9 genome-ed

82 Endovascular management of SMAA proved to be safe and efficient.

83 INTERPRETATION: The eSHC is safe and feasible for management of patients with chlamy

84 hat intraoperative fluorescence imaging is a safe and feasible method to assess anastomotic perfusion

85 sonance imaging (86%-89% sensitivity) (where safe and feasible), the Hammersmith Infant Neurological

86 y scan with oral and intravenous contrast is safe and feasible, whereas performance of esophageal end

87 ssion with the intent to cure) appears to be safe and has become the preferred approach for men with

88 or without ribavirin, for 16 or 24 weeks was safe and highly effective in participants with HCV infec

89 tein is replaced with EBOV GP (rVSV-EBOV) is safe and highly efficacious.

90 NA coding for antigens have been shown to be safe and immunogenic in preclinical models.

91 Thus far, it has proven to be safe and immunogenic, but it is expected that a more pot

92 e adults aged 50-65 years and found it to be safe and immunogenic.

93 tuberculosis patients have been found to be safe and improve lung immunity.

94 this study, HIV self-testing appeared to be safe and increased recent and repeat HIV testing among F

95 unsafe abortions into two categories of less safe and least safe.

96 VIT proved to be safe and no fatalities were recorded in the studies incl

97 hat NLS has potential for development into a safe and potent alternative therapy for prostate cancer

98 Artificial muscles hold promise for safe and powerful actuation for myriad common machines a

99 and to determine if it can be provided in a safe and practical manner to allow in-hospital human the

100 rozoite vaccine that has been reported to be safe and protective against P falciparum controlled huma

101 from local intestinal immunity, has yielded safe and protective orally administered cholera vaccines

102 Sofosbuvir-velpatasvir for 12 weeks was safe and provided high rates of SVR12 in patients coinfe

103 nd anatomy that precludes the possibility of safe and radical resection.

104 een weeks of diet and moderate exercise were safe and reduced BW and portal pressure in overweight/ob

105 TING-activating nanovaccine offers a simple, safe and robust strategy in boosting anti-tumour immunit

106 A safe and scalable synthesis of diaryliodonium triflates

107 or the patient, reliability of connectivity, safe and secure data transmission, and economic feasibil

108 ugs targeting the terminase complex could be safe and selective.

109 ironment that they had previously learned as safe and showed that increased theta- and gamma-oscillat

110 ach of IVF plus LD treatment is feasible and safe and significantly reduces rates of permanent shunt

111 nderused in daily practice, although it is a safe and simple procedure which can provide valuable cli

112 These results suggest that Lip-NLCs are a safe and simply prepared all-in-one platform for deliver

113 ctivity, detail a synthesis process yielding safe and stable compounds, and visualize how these nanom

114 immune and non-immune-mediated reactions was safe and successful in improving the uptake of first-lin

115 are prime candidates for the development of safe and sustainable energy storage systems.

116 can effectively induce immune activation at safe and tolerable clinical doses.

117 ed REP with efficient bioavailability may be safe and useful for dietary supplementation in MHD patie

118 treous injection of AAV2-sFLT01 seemed to be safe and well tolerated at all doses.

119 MVC-containing regimens were safe and well tolerated compared with TDF + FTC; this st

120 on of multipotent adult progenitor cells was safe and well tolerated in patients with acute ischaemic

121 INTERPRETATION: PF-00547659 was safe and well tolerated in this patient population, and

122 of radiotherapy alone should be considered a safe and well tolerated treatment for malignant dysphagi

123 emtricitabine, and tenofovir alafenamide was safe and well tolerated with better gastrointestinal tol

124 d all study injections, which were generally safe and well tolerated, with more immediate, but transi

125 h placebo, accelerated GE, and was generally safe and well tolerated.

126 es that a single infusion of elamipretide is safe and well tolerated.

127 Both vaccines were safe and well tolerated.

128 Maraviroc-containing PrEP regimens were safe and well-tolerated compared with TDF-FTC in U.S. wo

129 using solvent-assisted flavour evaporation (SAFE) and were mildly concentrated; extracts were subseq

130 Sufficient, safe, and continuously available water services are impo

131 lusion The use of banked VSTs is a feasible, safe, and effective approach to treat severe and drug-re

132 e met to make engineered T cells a reliable, safe, and effective platform that can be deployed agains

133 response to rituximab induction is feasible, safe, and effective.

134 llergy vaccines should be easily applicable, safe, and efficacious.

135 The THI provides a convenient, reliable, safe, and inexpensive means for tracking the thermal his

136 n USMI with MBKDR is clinically feasible and safe, and KDR-targeted USMI signal matches well with KDR

137 autoregulation-guided method is beneficial, safe, and most practical.

138 An effective, safe, and oral treatment for CL is required.

139 Both treatments were safe, and patients preferred the sublingual route of adm

140 roviral therapy (ART), now highly effective, safe, and simple.

141 Conclusion ACE is a feasible, safe, and well-tolerated treatment for patients with HCC

142 This safe antibacterial dye induces cell death and apoptosis

143 gative publicity by embracing a conservative/safe approach-seemingly ignoring research on economic/en

144 These findings suggest that selinexor is safe as a monotherapy in patients with relapsed or refra

145 iptin plus basal insulin is as effective and safe as, and a convenient alternative to, the labour-int

146 INTERPRETATION: Olesoxime was safe at the doses studied, for the duration of the trial

147 mean scores for the statement, "I would feel safe being treated here as a patient," were associated w

148 ng pregnancy for women with HIV results in a safe birthing trajectory, one not likely to jeopardize t

149 f delivering virulence factors together, are safe both in vitro and in vivo, and can elicit functiona

150 nts and continued for 24 days, appears to be safe but did not improve survival without BPD at 36 week

151 sient inhibition of apoptosis can serve as a safe but efficient alternative to improve the outcome of

152 DA+DCB treatment was effective and safe, but the study was not powered to show significant

153 TCEP was safe, captured embolic debris in 99% of patients, and di

154 ims to classify these drugs into harmful and safe categories using knowledge gained from chemoinforma

155 s of unknown pregnancy class into harmful or safe categories, focusing on two distinct outcomes: feta

156 featuring a decision between a gamble and a safe (certain) option on every trial.

157 coops, controlling animal movement, creating safe child spaces, improving veterinary care, and hygien

158 tients and mothers rated fewer situations as safe compared to male patients and fathers.

159 Conclusion IRE offers safe, complete ablation of HCC tumors in patients with c

160 When the CS-S was presented in the safe context, rats entered a long-lasting, anxiety-like

161 y are expected to provide an efficacious and safe CRISPR/Cas9 antimicrobial, broadly applicable to St

162 he contingencies for a threatening (CS+) and safe (CS-) stimulus reverse, in a prototypical disorder

163 d safety substudy showed both regimens to be safe, deliverable, and tolerable.

164 lidity of the cotton rat model itself and to safe development of nonlive RSV vaccines for seronegativ

165 sing allergic immune responses and achieving safe dietary reintroduction.

166 ion that involved the air puff than for the 'safe' direction.

167 oglobin concentration strongly discriminated safe discharge in the development cohort (C statistic 0.

168 modelling was used to identify predictors of safe discharge, defined as the absence of rebleeding, bl

169 oids was to determine the most effective and safe dose.

170 Effective and safe doses of opiate painkillers, like morphine, can be

171 gentamicin in clinical trials has shown that safe doses of this drug produce weak and variable readth

172 have reported MCL violations to the national Safe Drinking Water Information System (SDWIS).

173 Access to safe drinking water is a human right, crucial to combat

174 ty is a requirement for the development of a safe drug, and it is a critical property for chemical pr

175 vascular-targeted photodynamic therapy is a safe, effective treatment for low-risk, localised prosta

176 assessment to guide the optimum diffusion of safe, effective, and cost-effective health-care services

177 ccines might or might not succeed in raising safe, effective, and durable protection against human Zi

178 formation through gene transfer vectors in a safe, effective, and economical manner.

179 ions for oversight bodies that would support safe, effective, and ethical use of ketamine in depressi

180 whereby quality was defined as testing being safe, effective, patient-centered, timely, equitable, an

181 nting a promising choice for sustainable and safe energy storage.

182 new IFN-free regimens, highly effective and safe even in those historically considered "difficult to

183 acidic pH and cis-diols (such as mannitol, a safe FDA approved drug for diuresis) through particle si

184 industry to assist consumers with selecting safe foods for consumption.

185 l for developing novel strategies to deliver safe foods with appealing organoleptic attributes.

186 ed that a 370-MBq injection of (18)F-FAZA is safe for clinical use, similar to other widely used PET

187 tantial low-risk subset of patients possibly safe for early discharge without stress testing, a strat

188 The sorghum silages were found to be safe for feed consumption, since the ergot alkaloids and

189 e contaminants to ensure that groundwater is safe for human consumption and agricultural usage.

190 and cleaning methods must be acceptable and safe for intermittent catheter users.

191 INTERPRETATION: TKI de-escalation is safe for most patients with excellent responses to TKI t

192 travitreal corticosteroids are effective and safe for the management of ME associated with BRVO; howe

193 stion: Which interventions are effective and safe for treating female pattern hair loss (FPHL)?

194 cental barrier to enter fetal tissues and is safe for use in pregnant mice.

195 ing growth factor-beta (TGF-beta) signals in safe-guarding specific Treg cell functions.

196 derstanding the subtleties is the key to the safe handling and separations of the highly radioactive

197 The safe handling of category A infectious substances is a u

198 Continuous flow synthesis enables the safe handling of diazoalkanes at elevated temperatures,

199 teins, piRNAs, and slicer products, allowing safe handover of the intermediate.

200 1) efficient targeted transgene insertion at safe harbour loci (Rosa26 and AAVS1); (2) biallelic knoc

201 rovides impetus for further development of a safe, highly effective, and broad-spectrum RBD-based sub

202 l long-terminal-repeat enhancers have proven safe; however, transgene expression from cellular promot

203 Persistent Leishmania were not found in "safe" immunoprivileged cell types, instead residing in m

204 hy, including revascularization deferral, is safe in ACS.

205 effects in multiple animal models and to be safe in both animals and humans.

206 nistered primaquine dose would be relatively safe in G6PDd.

207 ation of warfarin treatment after PVI is not safe in high-risk patients, especially those who have pr

208 icin, which have recently been determined as safe in humans, could be administered as short courses t

209 muciniphila grown on the synthetic medium is safe in humans.

210 and SOF plus daclatasvir was efficacious and safe in LT, KT, and DLK transplant recipients; ribavirin

211 IVC was safe in patients and showed the possibility to prolong p

212 R-based deferral to medical treatment was as safe in patients with ACS as in patients with non-ACS (m

213 are recommended for post-LT patients are not safe in patients with severe renal impairment and patien

214 MT using a rationally derived stool donor is safe in recurrent HE compared to SOC alone.

215 Fondaparinux is effective and safe in suspected acute HIT; no HIT-specific complicatio

216 ltaG-CHIKV, VSVDeltaG-H5N1, and VLV were all safe in the adult mouse brain, as were VSVDeltaG viruses

217 ce many areas of research, and effective and safe in vivo mRNA delivery could fundamentally transform

218 In the present work a fast, reliable and safe Ion Exchange Chromatography-Pulsed Amperometry Dete

219 ective trials have found the procedure to be safe, it is unclear whether safe adaptation of this appr

220 in relation to GH risk in the Consortium on Safe Labor/Air Quality and Reproductive Health Study (Un

221 mended for virus inactivation and subsequent safe laboratory testing.

222 The LUNG SAFE (Large Observational Study to Understand the Global

223 h global access to sanitation is increasing, safe management of fecal waste is a rapidly growing chal

224 e potential of this "generally recognized as safe" material with minimal, low-energy bioprocessing, t

225 tin-secreting microbes may offer a novel and safe means of managing cholesterol metabolism and diet i

226 The advantages of SAFE measurement are discussed.

227 ay absorptiometry instruments now permit the safe measurement of BMD during pregnancy.We evaluated ma

228 aneous absorption and fluorescence emission (SAFE) measurement using a single commercial spectrofluor

229 serve as a degron, but rather provide a fail-safe mechanism that expands the range of RQC-degradable

230 U clinicians with evidence-based guidance on safe medication use practices for the critically ill.

231 PTBS with uncovered SEMS is an effective and safe method for palliative treatment of MBO.

232 toric IOL implantation is a predictable and safe method for the correction of high corneal astigmati

233 SAFE-MILND (NCT01500304) is a multicenter, phase I/II cl

234 ral-1 (NS1) protein from a clinically proven safe, Modified Vaccinia Ankara (MVA) vector, thus averti

235 Therefore, the development of a stable and safe next generation vaccine against the AMPV disease is

236 This emerging modality converts safe, non-ionizing light to ultrasound waves, enabling a

237 The safe, non-viral delivery of CRISPR/Cas components would

238 Ultrasound is a valuable, safe, nonionizing, cost effective, widely available, and

239 iodides from nuclear waste is important for safe nuclear energy usage, but remains a significant cha

240 (SEI) is demonstrated for the efficient and safe operation of a lithium metal anode.

241 on safe abortion to categorise abortions as safe or unsafe and to further divide unsafe abortions in

242 strointestinal bleeding who are suitable for safe outpatient management, which has important economic

243 s LCRs and Ca transient decay to insure fail-safe pacemaker cell operation within a wide range of rat

244 Safe patient handling behaviors and lift use were examin

245 In bivariate analysis, high safe patient handling behaviors were associated with sho

246 In multivariable logistic regression, high safe patient handling behaviors were significantly assoc

247 These data open the avenue for a safe pharmacological treatment that may prevent the neur

248 itis pseudoaneurysm is a relatively easy and safe procedure, and it can be considered as an alternati

249 water ((2)H2O) is a label commonly used for safe quantitative measurement of deuterium enrichment in

250 a quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction technique was adapted to deve

251 2 levels of critically ill patients within a safe range, as we do with other physiologic variables.

252 Angio-OCT is a safe, rapid imaging technique that could shed light on t

253 igatran with FEIBA 50 combination could be a safe remedy to avoid the deaths in clinics.

254 h Policies and Practices Study's Healthy and Safe School Environment questionnaire were analyzed.

255 A safe, simple, effective, and pan-genotypic regimen to tr

256 y to generalize fear from a threatening to a safe situation.

257 mainstay of risk reduction continues to be a safe sleep environment, as most infants who die suddenly

258 the adjusted analyses, mothers receiving the safe sleep mobile health intervention had higher prevale

259 ns separately and combined to promote infant safe sleep practices compared with control interventions

260 maternal self-reported adherence to 4 infant safe sleep practices of sleep position (supine), sleep l

261 this problem by repositioning effective and safe small-molecule drugs from other fields of medicine

262 o inhibit problematic Li dendrites and build safe solid Li-metal batteries.

263 ial analysis of fractionated eluates by SRM (SAFE-SRM), to plasma from cancer patients and discovered

264 lar lactate measurements can be a sensitive, safe, stable, and easy-to-implement research tool for me

265 able liquid offering one way of ensuring its safe storage and transportation before use.

266 ecisions are made is critical to achieving a safe strategy for imparting progressive responsibility.

267 ectors, control of invasive species, and the safe study of emerging biotechnology applications.

268 The Safe Surgery 2015 South Carolina program was designed to

269 uired for closing the hyo-laryngeal area for safe swallowing.

270 coordinated signaling pathways ensure a fail-safe system to prepare the oocyte for fertilization and

271 The safe-targeting guides allow for proper control of toxici

272 ng non-functional, non-genic regions (termed safe-targeting guides), in addition to non-targeting con

273 challenges of maintaining serum levels in a safe therapeutic range (1-3muM).

274 Vaccines and treatments should be safe to be used in pregnancy.

275 oducts are free from allergens and therefore safe to consume or have simply not undergone a risk asse

276 Probiotic bacteria are generally regarded as safe to consume, are bile-resistant and can plausibly be

277 vapor pressure and are therefore considered safe to handle.

278 The polymeric particles were safe to rat pulmonary arterial smooth muscle cell and to

279 GBCAs have shown efficacy and are safe to use with most patients; however, some GBCAs have

280 Here we report successful and safe transplantation of porcine islets with a bioartific

281 ses, has demonstrated to be an effective and safe treatment in LAR, increasing immunological toleranc

282 tion with hydrogel coils is an effective and safe treatment method for cerebral aneurysms, although i

283 ycemia, rendering GLP-1 analogs a useful and safe treatment modality in type 2 diabetes.

284 LDV/SOF without RBV is an effective and safe treatment option for patients with HCV genotype 4 i

285 tween participants in defining situations as safe, uncertain, or risky, but female patients and mothe

286 man, phase I clinical trial demonstrates the safe use and clinical potential of (68)Ga-NOTA-AE105 as

287 However, the correct, opportune, and safe use of rituximab for this indication remains to be

288 inicians must understand the appropriate and safe use of vaccines in patients with immunodeficiency.

289 rVSV) was shown to be a highly effective and safe vector for the delivery of foreign immunogens for v

290 LUNG SAFE was done during 4 consecutive weeks in winter, 2014

291 ater supply and redirect attention to ensure safe water among affected households.

292 s highlighted four main barriers to ensuring safe water for residents currently relying on private we

293 ntamination reduction via improved access to safe water or educational campaigns are also analyzed.

294 r provides a new, potentially effective, and safe way of generating reliable data in allergy multicen

295 and pegylated interferon alfa-2a therapy is safe, well tolerated, and establishes functional control

296 GSK2330672 treatment for 14 days was safe with no serious adverse events reported.

297 The RF technique is simple and safe, with results equivalent to the PF technique.

298 Safe work practices are important to reduce risk of inju

299 onal safety practices and culture to promote safe work practices for patient handling injury preventi

300 Response categories are green (I feel safe), yellow (I feel uncertain), or red (I feel everyth