ライフサイエンスコーパス: secretion

1 hormone and monoamine storage and regulated secretion.

2 knockdown abolished glucose-induced insulin secretion.

3 ion and gasdermin D-dependent interleukin-18 secretion.

4 meostasis resulting from an enhanced insulin secretion.

5 trol the viral infection involving IFN-gamma secretion.

6 istently inhibits insulin concentrations and secretion.

7 yRa x fasting insulin) x first-phase insulin secretion.

8 ase-containing exosomes and stimulates their secretion.

9 te and alterations in adiponectin and leptin secretion.

10 el, leading to reduced airway surface liquid secretion.

11 1 mRNA levels, but BBS4 also modulates FSTL1 secretion.

12 of muscarinic M3 receptor-stimulated insulin secretion.

13 echanism of P-CAB inhibition of gastric acid secretion.

14 ked glucose intolerance with reduced insulin secretion.

15 irulent M. marinum strain with reduced ESX-1 secretion.

16 ects in both insulin sensitivity and insulin secretion.

17 at PFAS alter glucose metabolism and insulin secretion.

18 beta-cell apoptosis and insufficient insulin secretion.

19 onsible for the galectin-3-mediated cytokine secretion.

20 potently silence gene expression and protein secretion.

21 n B resulted in decreased OA uptake and VLDL secretion.

22 roducing cells known to impair gonadotrophin secretion.

23 eptor site on SecA are essential for protein secretion.

24 ent and increased glucose-stimulated insulin secretion.

25 creatic beta-cells that impair fetal insulin secretion.

26 hibited GHRH-, but not ghrelin-stimulated GH-secretion.

27 due to defects in glucose-stimulated insulin secretion.

28 well as SNAP-23 and SNAP-29 completes cargo secretion.

29 in increased Th17 polarization and cytokine secretion.

30 EMO expression, NFkappaB activation, and IL6 secretion.

31 pected to produce adverse effects on insulin secretion.

32 interferon genes (STING)-dependent cytokine secretion.

33 d active gamma-glutamyltranspeptidase enzyme secretion.

34 nergetics control glucose-stimulated insulin secretion.

35 , where it mediates phosphatidylcholine (PC) secretion.

36 e of IGSF1 as regulator of pituitary hormone secretion.

37 NLRP3-mediated interleukin-1beta (IL-1beta) secretion.

38 e is an O-acyltransferase that regulates Wnt secretion.

39 creased insulin content and impaired insulin secretion.

40 LRP3 inflammasome-mediated interleukin-1beta secretion.

41 ciated with gonadotropin biosynthesis and/or secretion.

42 use parietal cells induced constitutive acid secretion.

43 ion of the substrates of this machine before secretion.

44 had detectable ZIKV RNA in saliva or vaginal secretions.

45 t least one oral pathogen in their prostatic secretions.

46 espectively; P = 0.9) or first-phase insulin secretion (-21 +/- 212 compared with 24 +/- 184 mU/L, re

47 e major protein-biogenic pathway for protein secretion across the cytoplasmic membrane or insertion o

48 M after their synthesis in the cytoplasm and secretion across the inner membrane.

49 Coupled with suppression of aldosterone secretion, activation of NCC helps to retain potassium b

50 mponent of the T1SS system abrogated type VI secretion activity under nutrient-limited conditions, in

51 ted to the plasma membrane, whereas their PC secretion activity was dramatically decreased.

52 murine asthma, mediating both AHR and mucus secretion after HDM exposure.

53 and IgE levels, and increased IL-4 and IL-13 secretion after MCT/EW challenge.

54 tors, SAR405 and VPS34-IN1, induced abnormal secretion and affected thrombus growth at arterial shear

55 ial dysfunction, and reduced type 1 collagen secretion and alkaline phosphatase activity.

56 , the NLRC3 CARD alone could dampen IL-1beta secretion and ASC speck formation induced by NALP3 mutan

57 with small differences in markers of insulin secretion and beta-cell function.

58 alpha that are critical for assembly-induced secretion and biological activity of IL-12 versus misfol

59 creases basal and glucose-stimulated insulin secretion and Ca(2+) uptake in the presence of glibencla

60 ted-macrophages showed reduction in IL-1beta secretion and caspase-1 activation.

61 isrupt the Golgi apparatus, interfering with secretion and compromising intestinal antimicrobial defe

62 neous injection of HC-HA/PTX3 preserved tear secretion and conjunctival goblet cell density and mitig

63 f LDB1 in mature beta cells impaired insulin secretion and glucose homeostasis.

64 , and that it cannot be given to induce such secretion and growth.

65 osolic Ca(2+) negatively regulates adipokine secretion and have uncovered an evolutionarily conserved

66 ted the importance of apolipoproteins in HCV secretion and infectivity, leading to the notion that HC

67 entially create an imbalance between insulin secretion and insulin-stimulated glucose utilization in

68 pendent increases of alpha and dense-granule secretion and integrin alphaIIbbeta3 activation, and agg

69 pression that was dependent on autocrine ATX secretion and LPA signaling.

70 ucose-stimulated Ca(2+) dynamics and insulin secretion and recapitulated the pattern of improved proi

71 e of similar bacterial DNA in both prostatic secretion and subgingival dental plaque from the same in

72 In CF-HBEC, TGF-beta increased KL secretion and upregulated FGF receptor (FGFR) 1.

73 Therefore, we studied B cell cytokine secretion and/or Ab production across obesity models.

74 entrations have been attributed to increased secretion and/or decreased insulin clearance by liver or

75 d high levels of bacterial shedding in nasal secretions and was temporally correlated with, and depen

76 a key role in membrane trafficking, vesicle secretion, and endocytosis.

77 ulation of antiapoptotic molecules, cytokine secretion, and enhanced effector function.

78 gy expenditure, insulin sensitivity, insulin secretion, and glucose tolerance.

79 mpaired glucose tolerance, defective insulin secretion, and increased apoptosis when a combined high-

80 il recruitment, interleukin-1beta [IL-1beta] secretion, and lactate dehydrogenase release) compared t

81 rongly inhibited B cell activation, cytokine secretion, and proliferation.

82 used to evaluate barrier function, cytokine secretion, and protein expression under basal conditions

83 inhibited T cell proliferation, blocked IL-2 secretion, and rendered T cells unresponsive to further

84 uscle contraction, airway and exocrine gland secretion, and rhythmic movements of the gastrointestina

85 se a reduction of insulin sensitivity and/or secretion (anti-incretin effect) to defend against hyper

86 or collagen-induced platelet aggregation and secretion are increased in TRAF3 knockout mice.

87 ng regulators of glucose sensing and hormone secretion, are differentially expressed in these cell ty

88 cA-RH7777 cells resulted in an increased TAG secretion as compared with cells co-expressing cathepsin

89 port a role for this gene product in protein secretion as well as in pili formation.

90 cose tolerance, cAMP production, and insulin secretion as well as protection against diabetes.

91 s (PBMCs) by intracellular staining and dual-secretion assay.

92 ly associated with lower first-phase insulin secretion but has no evidence for an effect on type 2 di

93 s by GDH in the L cell may explain why GLP-1 secretion, but not that of insulin, is activated by thes

94 Asn-168, Asn-538, and Asn-745 reduced rhDAO secretion by 13, 71, and 32%, respectively.

95 though glucose is known to stimulate insulin secretion by beta cells, whether it directly engages nut

96 ets, since Ex-4 treatment stimulated insulin secretion by both juvenile and adult human beta cells.

97 We aim to increase insulin secretion by developing strategies that work through mec

98 s a hub molecule during collagen folding and secretion by directing other molecules to reach their ta

99 however, their effects on secondary exosome secretion by distal organs have not been explored.

100 (HR) expression were detected by qPCR and HA secretion by enzymatic immunoassay.

101 Regulation of glucagon secretion by factors secreted by neighbouring beta- and

102 and TGF-beta1 significantly reduce cytokine secretion by ILC2s.

103 thermore, we show that BM components require secretion by migrating macrophages (hemocytes) during th

104 of rapamycin's inhibitory effect on IL-1beta secretion by the IL-1 receptor antagonist anakinra in ph

105 ence of native AVR3a is cleaved off prior to secretion by the pathogen and the N terminus of the matu

106 L) in combination also greatly stimulate TNF secretion (by 4,500-fold).

107 erarchical trafficking regulation in protein secretion channels.

108 ferential effects of male and female gonadal secretions (commonly referred to as sex hormones), which

109 slow gastric emptying and alter gut hormone secretion compared with a control but have no suppressiv

110 ered the proteomic profiles of airway apical secretions compared to cigarette-exposed HBECs.

111 Recent studies have characterized secretion components and mechanisms of type VII secretio

112 rapamycin (mTOR) kinase, promotes glutamate secretion, cystine uptake, and incorporation into glutat

113 We found that glucose-induced insulin secretion declined by 50% in rats housed at 5 degrees C

114 al activity, 24-h glycemia, and 24-h insulin secretion did not differ between intervention days.

115 ase (PD) and include disruption of melatonin secretion, disturbances of glucose, insulin resistance a

116 ded head-of-bed elevation, use of subglottic secretion drainage endotracheal tubes, oral care, chlorh

117 mportance of PKR, TRIF, and TBK1 in cytokine secretion during L. pneumophila infection of macrophages

118 okine (macrophage inflammatory protein 1beta secretion) effector responses.

119 also inhibited Ca(2+) concentration, hormone secretion/expression and proliferation.

120 um liver tests, bile flow, biliary bile salt secretion, fecal bile salt loss, and expression of major

121 of Vascular Endothelial Growth Factor (VEGF) secretion for this pathway of hypoxia-mediated self-rene

122 Silencing of Rab5 shifts receptor-triggered secretion from a compound to a full exocytosis mode, in

123 The recovery of regulated glucagon secretion from alpha-cells in small pseudoislets depends

124 re associated with reduced pituitary hormone secretion from AtT-20 cells.

125 rthermore, the TsSP-induced reduction of TNF secretion from DCs is reversed by receptor antagonists f

126 lpha-mediated gamma-aminobutyric acid (GABA) secretion from muscle.

127 825 did not affect pro-inflammatory cytokine secretion from other ROCK-positive cell types, corrobora

128 rol glucagon-like adipokinetic hormone (AKH) secretion from specialized neuroendocrine cells.

129 nflammatory mechanism demonstrated that IL-6 secretion from synovial fibroblasts was induced by chond

130 re of cultured neurons to fetal plasma or to secretions from the placenta or from model trophoblast b

131 biosynthesis and glucose-stimulated insulin secretion (GSIS) in a PKA-dependent manner and prevented

132 ghrelin inhibits glucose-stimulated insulin secretion (GSIS), the effect of obestatin on GSIS is unc

133 rtly by enhancing glucose-stimulated insulin secretion (GSIS).

134 The role of CTD phosphorylation in virion secretion, if any, has remained unclear.

135 down impaired IL-1beta-induced IL-6 and IL-8 secretion in cultured HGF and HPLF.

136 re likely to contribute to defective insulin secretion in human carriers of PAX6 mutations.

137 uced pyroptosis and proinflammatory cytokine secretion in macrophages.

138 doses of BPA significantly impaired insulin secretion in male but not female F1 and F2 offspring.

139 CMPF inhibits insulin secretion in mouse and human islets in vitro and in vivo

140 is necessary for glucose-stimulated insulin secretion in mouse and human islets.

141 l pathway as an important mechanism for mHtt secretion in mouse neuroblastoma and striatal cell lines

142 These findings suggest that insulin secretion in pancreatic cells is regulated by Ca(2+) and

143 ctional effects on parathyroid hormone (PTH) secretion in parathyroid neoplasms.

144 retion components and mechanisms of type VII secretion in pathogenic and environmental bacteria.

145 in human diarrheas, (R)-BPO-27 blocked fluid secretion in primary cultures of enteroids from human sm

146 ma, p < 0.05) and reduced leukocyte cytokine secretion in response to lipopolysaccharide stimulation.

147 ith a caspase 1 inhibitor decreased IL-1beta secretion in response to oxLDL ICs.

148 novel signaling pathway contributing to IL-8 secretion in the CF bronchial epithelium with KL functio

149 crystallin in astrocytes to decrease exosome secretion in the HD brains, contributing to non-cell-aut

150 cient to depolarize the cell and evoke GLP-1 secretion in the model, suggesting a crucial role for SG

151 ot distinguish loss of function from loss of secretion in these assays.

152 y, let-7 and miR-148 antagonism modified PTH secretion in vivo and in vitro, implying roles for these

153 ers similar stress responses (corticosterone secretion) in brood bystanders.

154 NEMO-mediated regulation of NFkappaB and IL6 secretion, increased phosphorylation of STAT3 on Ser727,

155 stance, synergistically with lowered insulin secretion, increases serum glucose levels, which stimula

156 beta-cell function measured with the insulin secretion/insulin sensitivity (disposition) index increa

157 Reported as a cancer biomarker, AMF secretion into body fluids might be closely related to m

158 ntegrity, morphology, phenotype and cytokine secretion into storage buffer.

159 -terminal signal peptide that mediates APOL1 secretion into the circulation.

160 ing, we monitored stimulus-coupled glandular secretion into the flytrap.

161 lecular chaperones to promote expressed SrtA secretion into the medium at high levels.

162 onstrate that increased EGFL7 expression and secretion is an autocrine mechanism supporting growth of

163 Normal renin synthesis and secretion is important for the maintenance of juxtaglome

164 actin recovers at the synapse and no further secretion is observed.

165 that minimizing the driving force for Cl(-) secretion is the main requirement for secreting 140 mm H

166 ing mechanisms are unknown, massive cytokine secretion is thought to be involved.

167 The role of mature domains in targeting and secretion is unclear.

168 Analysis of secretion kinetics identified a first phase (0-2 min) me

169 his organization underlies disturbed insulin secretion kinetics in T2D.

170 ting amino acid catabolism, as were cytokine secretion levels and regulatory T cell numbers.

171 lex (TraC and TraG) with homology to type IV secretion-like systems.

172 tion required for the assembly of the entire secretion machine.

173 epletion of goblet cell metaplasia and mucus secretion markers after HDM exposure.

174 Heterogeneity in LEP expression and secretion may influence the reparative proficiency of AP

175 ns, suggesting that increased endogenous OXT secretion may underlie this improvement.

176 ogeneity may be associated with the original secretion mechanism of a particular growth factor.

177 lone did increase beta cell mass and insulin secretion moderately.

178 ation of this effector, termed Tne2 (Type VI secretion NADase effector family 2), demonstrates that i

179 Furthermore, reduced cytokine secretion observed at high Ag density for both TCRs and

180 In alphaRaptorKO mice, impaired glucagon secretion occurred in response to different secretagogue

181 ted over time in addition to increased urine secretion of 8-oxo-deoxyguanosine.

182 n Ussing chambers and measured transcellular secretion of [(14)C]oxalate.

183 henomena are due, in part, to the deployment/secretion of a "decoy flare," for example, anomalous can

184 We further show that 4-PBA triggers the secretion of a KDEL-tagged luminal resident, implying th

185 lar replicative cycle of T. gondii including secretion of adhesins, motility, invasion, and egress.

186 mpounds that prime microbial pattern-induced secretion of antimicrobial furanocoumarins (phytoalexins

187 As a result, normal production and secretion of appetite control hormones, PYY, alpha-MSH,

188 dings imply a role for the RxLR motif in the secretion of AVR3a by the pathogen, rather than a direct

189 ved, blue light filters reduce light-induced secretion of bFGF and VEGF to near normal levels.

190 th in vivo and in vitro, as characterized by secretion of both proinflammatory and anti-inflammatory

191 urb protein folding, assembly or polarity of secretion of C1QTNF5 and, importantly, all appear to des

192 g by MSC was found to be mediated in part by secretion of cathelicidin and was significantly increase

193 The altered bile salt pool stimulated robust secretion of cholesterol into the intestinal lumen via t

194 als are a major endocrine site of production/secretion of constitutive pepcan-12, as shown by its mar

195 pathway that can be targeted to inhibit the secretion of cytokines by modulating either CXCR4 or CXC

196 une activation associated with a large local secretion of cytokines.

197 riptomic signature suggesting expression and secretion of extracellular proteins, while mature RRCs e

198 e mechanisms that mediate the unconventional secretion of FABP4.

199 Blocking of FDC secretion of IFN-alpha restored B cell tolerance and red

200 phase of TLR signaling and the TLR-dependent secretion of IL-10 (controlled by IRAKs 1 and 2) was onl

201 n armored CAR T cell capable of constitutive secretion of IL-12, and delineate the mechanisms via whi

202 rm cytotrophoblast cells, with a predominant secretion of IL-1beta and IL-6, a result confirmed in hu

203 The secretion of IL-1beta requires a unique protease, caspas

204 ecifically released by DCs, even when T cell secretion of IL-2 is intact.

205 of Vgamma9/Vdelta2 T cells promoted mucosal secretion of IL-22 and ICOSL/TNF-alpha-dependent release

206 anti-inflammatory IL-10, and stimulated the secretion of IL-6.

207 immune system to maintain homeostasis is the secretion of immunoglobulins (Igs) across epithelial bar

208 rd an inflammatory phenotype, with increased secretion of inflammatory cytokines as well as chemokine

209 y HOCl treatment was demonstrated by reduced secretion of inflammatory cytokines in affected skin tis

210 ereas knockdown of Irf5 blunted CB1R-induced secretion of inflammatory cytokines without affecting CC

211 PPARgamma/RXRalpha that inhibits expression/secretion of inflammatory cytokines.

212 It enhances the secretion of insulin, but attenuates insulin's metabolic

213 Secretion of interleukin 1beta (IL-1beta), in response t

214 ed epidermal structure, ascribed to aberrant secretion of lamellar bodies, which are essential for ep

215 Thus, failures in the secretion of nonbulky proteins, ER stress, and defective

216 Ga stress induces root secretion of organic acids such as citrate and malate.

217 f pathogenic lymphocyte infiltration and the secretion of pro-inflammatory cytokines are involved in

218 In vitro, these dendrimers reduced the secretion of proinflammatory cytokines from mice and hum

219 ive pathway prevents the correct folding and secretion of proteins that are known to form non-native

220 raves' disease, but not control sera, led to secretion of TG with an increased intrinsic ability to f

221 minent example of bacterial cooperation, the secretion of the peptide siderophore pyoverdine by Pseud

222 mutants promote longevity through increased secretion of the polysaccharide colanic acid (CA), which

223 inflammasome results in caspase-1-dependent secretion of the proinflammatory cytokines IL-1beta and

224 A2 activity in these splenic macrophages and secretion of the resistance-inducing lipid mediator, lys

225 osa as a model system, the authors show that secretion of the siderophore pyoverdine only incurs a fi

226 In vitro secretion of these miRNAs by peripheral blood mononuclea

227 The ECM did not affect the secretion of tissue inhibitors of metalloproteinases-1 o

228 cript and in a cell-based assay impaired the secretion of truncated LGI4 protein.

229 s of new protein, is not caused by decreased secretion of TSP-4, and is mediated by activation of SMA

230 y, leading to the notion that HCV coopts the secretion of very-low-density lipoprotein (VLDL) for its

231 Importantly, secretion of wild-type human SOD1 and the ALS-linked mut

232 elastine prevented the early effect of nasal secretions of AR patients on epithelial integrity.

233 To understand the adhesive secretions of P. shermani, its components were chemicall

234 the MMAR_0039 gene is not required for Esx-1 secretion or virulence.

235 teps such as entry, processing, assembly and secretion, or viral host factors.

236 present in 'pure' versus 'mixed' anal-gland secretions ('paste') of adult meerkats (Suricata suricat

237 us intermedius mediate cell contact- and Esx secretion pathway-dependent growth inhibition of diverse

238 ry autophagy, an autophagy-based alternative secretion pathway.

239 te the effects that clathrin defects have on secretion pathways and plant growth.

240 During exosome secretion, phosphorylated PKM2 serves as a protein kinas

241 that uterine glands and, by inference, their secretions play important roles in blastocyst implantati

242 analog on KATP channel activity and insulin secretion point to participation of the cGMP/PKG and cAM

243 reases NALP3-induced IL-1beta maturation and secretion, pro-caspase-1 cleavage, and speck formation b

244 Inspired by the secretion process and natural cargo delivery functions o

245 uding regulation of insulin biosynthesis and secretion, promotion of satiety, and preservation of bet

246 hydrpxnonenal both assayed by ELISA, insulin secretion quantified using ELISA or radioimmunoassay, an

247 n of TLR4 or SPAK normalizes hyperactive CSF secretion rates and reduces PHH symptoms, as does treatm

248 Adipose tissue RBP4 expression and secretion remained intact in LRKO mice and increased as

249 characterized by airway inflammation, mucus secretion, remodeling and hyperresponsiveness (AHR).

250 dges in IL-12alpha are dispensable for IL-12 secretion, stability, and biological activity.

251 se homeostasis, insulin sensitivity, insulin secretion, steatosis, metabolic inflammation, pancreatic

252 flammasome activation, cell death, and IL-18 secretion, suggesting that restoring mitophagy and inhib

253 ter species produce both a functional type I secretion system (T1SS) and a contact-dependent inhibiti

254 some upon sensing components of the type III secretion system (T3SS) and flagellar apparatus.

255 enic Gram-negative bacteria use the type III secretion system (T3SS) to deliver effector proteins int

256 The type VI secretion system (T6SS) is a contact-dependent bacterial

257 genetic architectures (GA1-3) of the type VI secretion system (T6SS), an effector delivery pathway th

258 These processes depend on type 6 secretion system 1 (T6SS-1), which is required for virul

259 ia an unknown mechanism by bacterial type VI secretion system 5 (T6SS-5), which is an essential virul

260 m and is actively suppressed by the type III secretion system and its effector proteins.

261 The Pseudomonas aeruginosa type III secretion system delivers effector proteins directly int

262 el apparatus, a widespread exopolysaccharide secretion system found in environmental and pathogenic b

263 The Dot/Icm-type IVB secretion system is essential for the biogenesis of the

264 V tag, which can pass through the type three secretion system, allowed visualization and quantificati

265 omplex, IcmSW, for translocation through the secretion system, but its role in pathogenicity has rema

266 ified the mRNA for the regulator of type III secretion system.

267 s components of the virulence-critical ESX-1 secretion system.

268 ane as unfolded amyloid precursors through a secretion system.

269 Type III protein secretion systems have specifically evolved to deliver b

270 d homologs of this toxin are associated with secretion systems in many Gram-negative and Gram-positiv

271 luding membrane transport from which type VI secretion systems were in particular upregulated.

272 the Liberibacter virulence traits, including secretion systems, putative effectors, and lipopolysacch

273 Type II secretion (T2S) is one means by which Gram-negative path

274 is mode of protein export is termed type-III secretion (T3S).

275 Tsc1 deletion results in an increase in CTGF secretion that non-cell autonomously stunts oligodendroc

276 uring pancreatitis maintains VAMP8-dependent secretion, thereby preventing accumulation of activated

277 Reduction of gastric acid secretion therefore appears to promote overgrowth of int

278 osmolarity stimulate thirst and vasopressin secretion through a central osmoreceptor; however, centr

279 ion with sIL-6R promoted VEGF expression and secretion through a transcriptional mechanism involving

280 ype 1 (AT1R), stimulates acute catecholamine secretion through coupling with the transient receptor p

281 oteins and inducing proinflammatory cytokine secretion through protease-activated receptor 2 (PAR2).

282 cardiomyocytes decreased VEGF expression and secretion to levels sufficient to blunt in vitro tube fo

283 Acute hormone secretion triggered by G protein-coupled receptor (GPCR)

284 riggering cellular cytotoxicity and cytokine secretion upon high-affinity interaction with the cognat

285 ncreases in KL, TGF-beta also increased IL-8 secretion via activation of FGFR1 and Smad 3 signaling.

286 s reveals that Drp1 does not control insulin secretion via its effect on proton leak but instead via

287 progesterone inhibits LH surge and pulsatile secretion via its receptor in the ARC and/or AVPV nuclei

288 O2 consumption, and ATP production), insulin secretion was almost completely restored at elevated glu

289 tic properties in vitro cBiTE expression and secretion was detected in supernatants from ICOVIR-15K-c

290 ximately 60%, and glucose-stimulated insulin secretion was eliminated.

291 Finally, CXCL10-increased MMP-9 secretion was inhibited by methylprednisolone and also b

292 Pressure-induced secretion was inhibited by the mechanosensitive ion chan

293 50s genes involved in the biosynthesis of MG secretions, we analyzed by means of qPCR, the expression

294 conceptus aromatase expression and estrogen secretion were decreased, indicating that IL1B2 may be i

295 ctivation/fibrosis, and TGF-beta1 expression/secretion were decreased.

296 ven by increased tumor necrosis factor (TNF) secretion, which leads to activation in turn of c-Jun N-

297 human macrophages exposed to HCV induce CCL5 secretion, which plays a significant role in hepatic inf

298 mportant in ensuring that excessive chloride secretion, with the accompanying loss of fluid, is not n

299 pletion of TANGO1 in HSCs blocked collagen I secretion without affecting other matrix proteins.

300 th necessary and sufficient to cause exosome secretion without affecting the endoplasmic reticulum/Go