ライフサイエンスコーパス: secretor

1 y (P < .001 for each variable, compared with secretors).

2 ting and therefore filamented bacteria (high secretors).

3 ic E. coli isolates compared with cells from secretors.

4 l P[8]/P[4] rotavirus infected children were secretors.

5 R that prepares cells to become professional secretors.

6 pectrum to saliva samples of all A, B, and O secretors.

7 GII.4 norovirus exclusively infected secretors.

8 effector programs, but remained stable IL-17 secretors.

9 competent cytotoxic effectors and IFN-gamma secretors.

10 frequencies of cross-reactive IL-4 and IL-2 secretors.

11 Of the 23 secretors, 16 (70%) were infected with norovirus, 13 (57

12 ildren of European or African ancestry to be secretors (96% vs 74%; P < .001).

13 The presence of histo-blood group antigens (secretor, ABO, and Lewis type) was determined in saliva.

14 Secretor and Lewis, but not A or B antigens, were presen

15 Forty healthy adults (23 secretors and 17 nonsecretors of HBGAs) were challenged

16 ells are capable of acting as both IFN-gamma secretors and cytotoxic T lymphocyte (CTL) effectors; ho

17 ive status, including those with A, B, and O secretors and Lewis positive blood types, were sensitive

18 robability of death after bacteremia between secretors and nonsecretors (p = .02).

19 HMO concentrations from women classified as secretors and nonsecretors, a phenotype that can be iden

20 , were sensitive to the virus, while the non-secretors and the Lewis negative individual were not.

21 fferent histo-blood types, defined by Lewis, secretor, and ABO types.

22 he GI.7 strain bound to H- and A-type, Lewis secretor, and Lewis nonsecretor families of HBGAs, allow

23 arious types 1 and 2 HBGAs, including Lewis, secretor, and nonsecretor antigens, distributing on the

24 ree patterns (VA387, NV, and MOH) recognized secretors, and 1 pattern (VA207) recognized Lewis-positi

25 (a+ b-) (nonsecretor) rather than Le(a- b+) (secretor) blood type.

26 Secretors comprised all 155 cases and 21 asymptomatic in

27 -Q elicited IL-4 and IL-2, but not IFN-gamma secretors cross-reactive with PLP-139-151.

28 s that do not secrete IL-9, as purified IL-9 secretors demonstrate the same loss of IL-9 in subsequen

29 mained elevated through day 180, and was not secretor dependent.

30 ions is determined by genetically controlled secretor-dependent expression of histo-blood group antig

31 re potent and biologically relevant cytokine secretors during stress-mediated hematopoiesis.

32 This "social insulation" protects secretors from competition with nonsecretors of the same

33 uals with a functional FUT2 gene are termed "secretors." FUT2 polymorphisms may influence viral bindi

34 viduals have a functional copy of the FUT2 ("secretor") gene required for gut HBGA expression; these

35 ABO non-secretor genotypes for two ancestry-specific FUT2 SNPs s

36 (n=843) expressing the combined MBL2 5' LYQA secretor haplotype (CGTCGG) and 3' haplotype (CGGGT) was

37 Inclusion of the combined MBL2 LYQA secretor haplotype improved prediction models for PMI ba

38 The combined MBL2 LYQA secretor haplotype in whites was also an independent pre

39 The combined MBL2 LYQA secretor haplotype is a novel independent predictor of P

40 Moreover, the combined MBL2 LYQA secretor haplotype was an independent predictor of PMI i

41 ntraoperative variables to determine if MBL2 secretor haplotypes are independent predictors of PMI in

42 We found that 5' secretor haplotypes known to correlate with moderate and

43 Within the MBL2 gene are seven 5' "secretor" haplotypes that code for altered serum MBL lev

44 P genotypes of human RVs interacts with the secretor histo-blood group antigens (HBGAs).

45 exchanger 2 (AE2), the principal bicarbonate secretor in the human biliary tree, is down-regulated in

46 certain Mm non-producing mutants to act as 'secretors' in cosynthesis with other 'convertor' mutants

47 enhanced functionality (i.e., multicytokine secretors, including IL-2; enhanced CD137 and CD107a exp

48 ]/P[4] rotaviruses bound saliva samples from secretor individuals.

49 ain structure of a 2004 variant with ABH and secretor Lewis HBGAs and compared it with the previously

50 hat all P[8]-infected children (n = 22) were secretor Lewis positive.

51 d to be nonsusceptible on the basis of being secretor negative.

52 rates of non-GII.4 infections were found in secretor-negative children (relative risk, 0.56; P = .02

53 on-GII.4 infections were more often found in secretor-negative children.

54 tion, cases of NoV infection associated with secretor-negative individuals are reported.

55 Neither Secretor nor Lewis status distinguished between transmit

56 tzii A2-165 and Clostridium hathewayi, a low secretor of IL-10, on the Th1-driven inflammatory respon

57 thcare-acquired infections and is a prolific secretor of proteins, including three chitinases (ChiA,

58 ells (pDCs) have been identified as a potent secretor of the type I interferons (IFNs) in response to

59 y in a cell line (UM-SCC-1) which is an avid secretor of this collagenase.

60 only as a permeability barrier but also as a secretor of urinary proteins that can play physiological

61 only 2 (5%) of 44 consistent or intermittent secretors of acid had ratios in this range (P<.001).

62 ing tumour was a prolactinoma; three ectopic secretors of ACTH (two bronchial and one thymic carcinoi

63 resenting cells for T cell activation and as secretors of antigen-specific antibodies.

64 0 aa not linked to a signal peptide are poor secretors of IL-16 and show little if any resistance to

65 Filamentous fungi are native secretors of lignocellulolytic enzymes and are used as p

66 tional CD4(+) effector T cells identified as secretors of prototypical cytokines IFNgamma, IL4, IL9,

67 transplant recipients studied who were high secretors of S-HLA-I postoperatively carried HLA-A24 or

68 n subjects with HLA-A23 or HLA-A24 were high secretors of S-HLA-I.

69 -SCC-1 and MDA-TU-138) characterized as avid secretors of the plasminogen activator.

70 whereas strain MOH binds to HBGAs of A and B secretors only.

71 ikely than norovirus-negative controls to be secretors (P < .001) in a logistic regression model adju

72 The relationship between ABO-Le secretor phenotype and susceptibility to recurrent idiop

73 This allele determines the secretor phenotype in which blood group antigens are fou

74 ltransferase gene (FUT2) responsible for the secretor phenotype is required for susceptibility to Nor

75 um P[8]/P[4]-specific IgG and host Lewis and secretor phenotypes has been found among 206 studied ser

76 atic patients showed that individuals with a secretor positive status, including those with A, B, and

77 ximately 1320 genomic equivalents [gEq]) for secretor-positive blood group O or A persons and 7.0 (ap

78 RV strains (n = 27) infected only Lewis- and secretor-positive children (27/27; P < .0001), but no Le

79 II, genotype 4 (GII.4) infections were among secretor-positive children (P < .001), but higher rates

80 GII.4 infections were uniquely detected in secretor-positive children, while non-GII.4 infections w

81 norovirus strains infected various types of secretor-positive individuals (types A, B, and O).

82 Among 18 infected secretor-positive individuals, blocking titers peaked by

83 targeting of new variants to Lewis-positive, secretor-positive individuals.

84 Only secretor-positive participants maintained high avidity b

85 ons and 7.0 (approximately 2800 gEq) for all secretor-positive persons.

86 Although secretor-positive status is strongly correlated with NoV

87 The 3 secretor-recognizing patterns were defined as A/B (MOH),

88 Infection occurred in secretors regardless of ABO blood group.

89 ls and increased ratios of IFN-gamma to IL-4 secretors responsive to PLP-139-151.

90 Fifty-four women were secretors (Se+), and 6 were nonsecretors (Se-).

91 EC and determined that nonsecretors (but not secretors) selectively express two extended globoseries

92 lyses assessed the preventive association of secretor status against severe rotavirus gastroenteritis

93 Salivary DNA was collected to determine secretor status and genetic ancestry.

94 d whether an association exists between FUT2 secretor status and laboratory-confirmed rotavirus infec

95 Secretor status determined the susceptibility to norovir

96 A genetic polymorphism affecting FUT2 secretor status in approximately one-quarter of humans o

97 A24 or HLA-A29 resulted in the observed high secretor status in liver transplant recipients after tra

98 tibility to some noroviruses depends on FUT2 secretor status, but the population impact of this assoc

99 specimens were tested for rotavirus and for secretor status.

100 sociation of infection and disease with FUT2 secretor status.

101 wis-positive children, irrespective of their secretor status.

102 were marginally influenced by their mother's secretor status.

103 cosyltransferase that determines blood group secretor status.

104 infection was not dependent upon blood group secretor status.

105 Secretor statuses were found to correlate with the risk

106 nvironment, however, our model predicts that secretor strains of any one species will be surrounded b

107 expression; these individuals are known as "secretors." Susceptibility to some noroviruses depends o

108 igh proportion of nonsecreting bacteria (low secretors) than from populations with a high proportion

109 CA11 gene appears to be located between the secretor type alpha(1,2)-fucosyltransferase gene cluster

110 or substrate specificity resembles the human Secretor-type alpha1,2- FTase.

111 We found that secretors were 9.9 times (95% confidence interval [CI],

112 Secretors were also 26.6 times more susceptible to infec

113 IgA secretors were prominent in the early AFC response to in

114 Strain VA387 binds to HBGAs of A, B, and O secretors, whereas strain MOH binds to HBGAs of A and B

115 Twenty percent of Caucasians are 'non-secretors' who do not express ABO antigens in saliva as

116 s Pseudomonas aeruginosa, a prolific protein secretor with the potential to produce seven different s

117 d by FUT2), an intermediate rate (30%) among secretors with non-blood group O, and the highest rate (

118 od group O, and the highest rate (51%) among secretors with O blood group.